locus-tag	class	description
GSR62_RS00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
GSR62_RS00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
GSR62_RS00015	ENOG410848D	S4 domain protein YaaA
GSR62_RS00020	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
GSR62_RS00025	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GSR62_RS00030	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GSR62_RS00035	ENOG4108RYK	Nad-dependent epimerase dehydratase
GSR62_RS00040	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
GSR62_RS00045	ENOG4108UUM	single-stranded DNA-binding protein
GSR62_RS00080	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
GSR62_RS00085	ENOG4105CDU	Replicative dna helicase
GSR62_RS00090	ENOG4105CAQ	asparagine synthetase
GSR62_RS00100	ENOG4105CFH	Aspartokinase
GSR62_RS00105	ENOG4105D98	threonine synthase
GSR62_RS00110	ENOG4105D6E	homoserine dehydrogenase
GSR62_RS00120	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
GSR62_RS00140	ENOG4107TTW	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
GSR62_RS00150	ENOG4108N2Y	auxin Efflux
GSR62_RS00155	ENOG4105CFN	oxalyl-CoA decarboxylase
GSR62_RS00160	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
GSR62_RS00175	ENOG4105C6T	cysteine synthase
GSR62_RS00180	ENOG4105C7N	Xanthine uracil vitamin C permease
GSR62_RS00195	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
GSR62_RS00200	ENOG4107QJZ	Glycosyl transferase, family 2
GSR62_RS00205	ENOG4105C6N	Formate acetyltransferase
GSR62_RS00210	ENOG4105F1A	Pyruvate formate-lyase
GSR62_RS00225	ENOG4108S4H	thioesterase Superfamily protein
GSR62_RS00270	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GSR62_RS00275	ENOG4105BZU	Histidine kinase
GSR62_RS00290	ENOG4105Q2H	domain protein
GSR62_RS00295	ENOG4105C0H	protease
GSR62_RS00300	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
GSR62_RS00315	ENOG4105PY6	Phenolic acid decarboxylase
GSR62_RS00385	ENOG4105ZMH	deoxynucleoside kinase
GSR62_RS00405	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
GSR62_RS00410	ENOG4105E5Q	amino acid AbC transporter
GSR62_RS00420	ENOG4105CM2	brancheD-chain amino acid aminotransferase
GSR62_RS00440	ENOG4105WPN	DNA integration recombination invertion protein
GSR62_RS00485	ENOG4105VUC	UPF0237 protein
GSR62_RS00490	ENOG4105CAG	UPF0210 protein
GSR62_RS00495	ENOG4105E98	transcriptional regulator DeoR family
GSR62_RS00500	ENOG4105DE4	1-phosphofructokinase
GSR62_RS00505	ENOG4105DM4	PTS System
GSR62_RS00535	ENOG4105CKK	Glycosyl transferase, family 2
GSR62_RS00550	ENOG4105D5D	udp-galactopyranose mutase
GSR62_RS00560	ENOG4105GH9	galactofuranosyltransferase
GSR62_RS00565	ENOG4105GH9	galactofuranosyltransferase
GSR62_RS00575	ENOG4107XU6	Glycosyl transferase (Group 1
GSR62_RS00585	ENOG4105D3Q	Sugar transferase
GSR62_RS00600	ENOG4105C59	p-type ATPase
GSR62_RS00605	ENOG4108RCR	degv family
GSR62_RS00630	ENOG4105HTX	biosynthesis protein
GSR62_RS00635	ENOG4107YJ4	chain length determinant protein
GSR62_RS00640	ENOG4108RB3	Capsular polysaccharide biosynthesis protein
GSR62_RS00645	ENOG4108KMV	Glycosyl transferase (Group 1
GSR62_RS00660	ENOG4108KMV	Glycosyl transferase (Group 1
GSR62_RS00690	ENOG4105D3Q	Sugar transferase
GSR62_RS00695	ENOG4105EAB	amino acid AbC transporter
GSR62_RS00700	ENOG4105CDA	abc transporter atp-binding protein
GSR62_RS00705	ENOG4105DRP	amino acid AbC transporter
GSR62_RS00720	ENOG4105DFD	Na H antiporter
GSR62_RS00725	ENOG4107TS3	membrane protein, TerC
GSR62_RS00735	ENOG4105K63	Thioredoxin
GSR62_RS00745	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
GSR62_RS00770	ENOG4106ISY	Putative cell wall binding repeat
GSR62_RS00785	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
GSR62_RS00790	ENOG4105C3S	Mate efflux family protein
GSR62_RS00795	ENOG4105EVU	fructokinase
GSR62_RS00810	ENOG4105WMR	Protein CrcB homolog
GSR62_RS00815	ENOG41084I6	Protein CrcB homolog
GSR62_RS00820	ENOG4108TZY	GntR Family Transcriptional Regulator
GSR62_RS00830	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
GSR62_RS00835	ENOG4107QHE	Choloylglycine hydrolase
GSR62_RS00840	ENOG4105GYP	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity)
GSR62_RS00855	ENOG4105CUB	amino acid
GSR62_RS00860	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
GSR62_RS00865	ENOG4105N80	Ferric uptake regulator, Fur family
GSR62_RS00890	ENOG4107R7I	amino acid
GSR62_RS00895	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
GSR62_RS00905	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
GSR62_RS00910	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GSR62_RS00920	ENOG4108JQ7	(ABC) transporter
GSR62_RS00930	ENOG4105C7N	Xanthine uracil vitamin C permease
GSR62_RS00935	ENOG4105CK1	PTS System
GSR62_RS00945	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
GSR62_RS00950	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
GSR62_RS00955	ENOG4108DBC	nitroreductase
GSR62_RS00970	ENOG4105BZU	Histidine kinase
GSR62_RS00980	ENOG4105ECB	domain protein
GSR62_RS00995	ENOG4108IUX	(ABC) transporter
GSR62_RS01035	ENOG4105CK1	PTS System
GSR62_RS01040	ENOG4105VZJ	PTS System
GSR62_RS01045	ENOG4105VCP	PTS System
GSR62_RS01055	ENOG4105CS2	ec 3.2.1.21
GSR62_RS01060	ENOG4107QTZ	amino acid
GSR62_RS01075	ENOG4108YBP	pseudouridine synthase
GSR62_RS01080	ENOG4107RPQ	ABC transporter
GSR62_RS01090	ENOG410605W	Major Facilitator
GSR62_RS01095	ENOG4108KGH	TRANSCRIPTIONal
GSR62_RS01130	ENOG4107FQX	Alpha-acetolactate decarboxylase
GSR62_RS01135	ENOG4108IQI	permease
GSR62_RS01140	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
GSR62_RS01145	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
GSR62_RS01245	ENOG4105K63	Thioredoxin
GSR62_RS01250	ENOG4105C3M	thioredoxin reductase
GSR62_RS01260	ENOG4105CMQ	Chloride channel
GSR62_RS01265	ENOG4105DJB	Major Facilitator Superfamily
GSR62_RS01275	ENOG4108IPT	Naphthoate synthase
GSR62_RS01285	ENOG4105CG3	alpha amylase, catalytic region
GSR62_RS01290	ENOG4107414	GntR family transcriptional regulator
GSR62_RS01295	ENOG4105C5Y	PTS System
GSR62_RS01300	ENOG4107RBJ	symporter
GSR62_RS01305	ENOG4105CQ4	Transcriptional regulator
GSR62_RS01330	ENOG41090PH	Protease synthase and sporulation negative regulatory protein pai 1
GSR62_RS01335	ENOG4108U05	Transcriptional regulator
GSR62_RS01340	ENOG410667J	hydrolase
GSR62_RS01350	ENOG4105C59	p-type ATPase
GSR62_RS01365	ENOG4108EKI	Dehydrogenase
GSR62_RS01380	ENOG4105D2M	Aldolase
GSR62_RS01385	ENOG4105FDP	GntR family transcriptional regulator
GSR62_RS01400	ENOG4108EQA	pts system
GSR62_RS01405	ENOG4105ETZ	PTS System
GSR62_RS01410	ENOG4105F3R	pts system mannose fructose sorbose family iid
GSR62_RS01420	ENOG4105E70	isomerase
GSR62_RS01425	ENOG4105CE4	GlcNAc 6-P deacetylase
GSR62_RS01445	ENOG4105CS2	ec 3.2.1.21
GSR62_RS01450	ENOG4105C5Y	PTS System
GSR62_RS01455	ENOG4105CID	antiterminator
GSR62_RS01465	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
GSR62_RS01510	ENOG4105DWK	Membrane
GSR62_RS01530	ENOG4105M2Z	protein tyrosine serine phosphatase
GSR62_RS01535	ENOG4105NAE	bifunctional deaminase-reductase domain protein
GSR62_RS01540	ENOG4105I3N	Conserved Protein
GSR62_RS01545	ENOG4105CV8	reductase
GSR62_RS01550	ENOG4107YDN	peptide deformylase
GSR62_RS01575	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
GSR62_RS01580	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
GSR62_RS01585	ENOG4108JA2	transcriptioN-repair coupling factor
GSR62_RS01595	ENOG41082I2	s4 domain protein
GSR62_RS01605	ENOG41060GV	RNA binding s1 domain protein
GSR62_RS01610	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
GSR62_RS01615	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
GSR62_RS01625	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
GSR62_RS01630	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
GSR62_RS01635	ENOG4105CRK	lysyL-tRNA synthetase
GSR62_RS01680	ENOG4105DUX	Transporter
GSR62_RS01695	ENOG4105II7	pyrroline-5-carboxylate reductase
GSR62_RS01700	ENOG4105CE4	GlcNAc 6-P deacetylase
GSR62_RS01705	ENOG4105FDP	GntR family transcriptional regulator
GSR62_RS01715	ENOG4105DU0	nucleoside hydrolase
GSR62_RS01725	ENOG4105DAP	Nicotinate phosphoribosyltransferase
GSR62_RS01730	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
GSR62_RS01735	ENOG4105C9U	ATP-dependent DNA helicase RecQ
GSR62_RS01745	ENOG410906U	SprT-like
GSR62_RS01755	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
GSR62_RS01760	ENOG41068JE	domain protein
GSR62_RS01765	ENOG4108KGH	TRANSCRIPTIONal
GSR62_RS01775	ENOG4108K79	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
GSR62_RS01785	ENOG4105E66	phosphoriboisomerase A
GSR62_RS01795	ENOG4107Z0P	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
GSR62_RS01805	ENOG4105CTP	PilT protein domain protein
GSR62_RS01810	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
GSR62_RS01815	ENOG4105C8N	cysteinyl-tRNA synthetase
GSR62_RS01820	ENOG4105KEB	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GSR62_RS01825	ENOG4105C2N	RNA methyltransferase TrmH family group 3
GSR62_RS01870	ENOG4108Z6X	(sortase) family
GSR62_RS01875	ENOG4107FTN	50S ribosomal protein L33
GSR62_RS01885	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
GSR62_RS01895	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
GSR62_RS01900	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
GSR62_RS01910	ENOG4105D7V	transposase
GSR62_RS01915	ENOG4105MZU	cell filamentation protein
GSR62_RS01920	ENOG4108VZM	50s ribosomal protein L10
GSR62_RS01925	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
GSR62_RS01930	ENOG4105CHF	Glutathione S-transferase
GSR62_RS01935	ENOG4105FF5	Membrane
GSR62_RS01945	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
GSR62_RS01950	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
GSR62_RS01955	ENOG4105MTF	NrdI protein
GSR62_RS01960	ENOG4105WAZ	(Glutaredoxin-like protein) NrdH
GSR62_RS01970	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
GSR62_RS01980	ENOG4105C5N	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
GSR62_RS01985	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
GSR62_RS01995	ENOG4105C5H	ABC transporter
GSR62_RS02000	ENOG4105S7A	ErfK ybiS ycfS ynhG family protein
GSR62_RS02005	ENOG4105S7A	ErfK ybiS ycfS ynhG family protein
GSR62_RS02010	ENOG4105DZW	Dipeptidase
GSR62_RS02020	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
GSR62_RS02025	ENOG4108UMI	ABC transporter, permease
GSR62_RS02030	ENOG4105D01	(LipO)protein
GSR62_RS02035	ENOG4105C37	(CBS) domain
GSR62_RS02045	ENOG4105CFI	type iii restriction protein res subunit
GSR62_RS02050	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
GSR62_RS02075	ENOG4105CBD	Diacylglycerol kinase
GSR62_RS02080	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
GSR62_RS02085	ENOG4107R37	Glutamate dehydrogenase
GSR62_RS02095	ENOG41080BT	SNARE associated Golgi
GSR62_RS02115	ENOG4105C88	aminopeptidase
GSR62_RS02120	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
GSR62_RS02140	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
GSR62_RS02145	ENOG41068JE	domain protein
GSR62_RS02150	ENOG4107U9T	Pfam:Ribonuclease_BN
GSR62_RS02155	ENOG410902V	Modulates RecA activity (By similarity)
GSR62_RS02160	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
GSR62_RS02165	ENOG4105EVI	UPF0374 protein
GSR62_RS02170	ENOG4105C02	permease
GSR62_RS02175	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
GSR62_RS02180	ENOG4105WH5	Teichoic acid glycosylation protein
GSR62_RS02190	ENOG4105C37	(CBS) domain
GSR62_RS02195	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
GSR62_RS02210	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
GSR62_RS02220	ENOG4105KRI	phosphocarrier protein (HPr
GSR62_RS02225	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
GSR62_RS02230	ENOG4105BZF	Glycosyl transferase (Group 1
GSR62_RS02235	ENOG4105W2C	Glycosyl transferase
GSR62_RS02250	ENOG4105E0M	Sulfatase
GSR62_RS02330	ENOG4105HMI	Membrane
GSR62_RS02335	ENOG4105CE1	Ferrous iron transport protein b
GSR62_RS02350	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
GSR62_RS02365	ENOG410667J	hydrolase
GSR62_RS02370	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
GSR62_RS02375	ENOG4108IJ2	phosphate acetyltransferase
GSR62_RS02380	ENOG4105K8N	protein family UPF0079, ATPase
GSR62_RS02385	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
GSR62_RS02390	ENOG4105CGK	Exodeoxyribonuclease III
GSR62_RS02395	ENOG4105D4A	Cell wall formation (By similarity)
GSR62_RS02410	ENOG4107U5W	ybbr family
GSR62_RS02415	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
GSR62_RS02425	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
GSR62_RS02430	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
GSR62_RS02435	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
GSR62_RS02440	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
GSR62_RS02455	ENOG4105CVA	phosphate
GSR62_RS02460	ENOG4105C8U	phosphate abc transporter
GSR62_RS02465	ENOG4105E2Z	phosphate ABC transporter (Permease
GSR62_RS02470	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
GSR62_RS02475	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
GSR62_RS02480	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
GSR62_RS02485	ENOG4105D2N	Aldolase
GSR62_RS02495	ENOG4108UT2	hemolysin iii
GSR62_RS02500	ENOG4107YCR	Transcriptional regulator, ARSR family
GSR62_RS02505	ENOG4108JJB	ABC transporter
GSR62_RS02510	ENOG4105C7J	ABC transporter, permease
GSR62_RS02525	ENOG4105E0M	Sulfatase
GSR62_RS02530	ENOG4105CSC	Glucose uptake protein
GSR62_RS02535	ENOG4107QYV	phosphohexose isomerase
GSR62_RS02545	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
GSR62_RS02555	ENOG4105D8X	mechanosensitive ion channel
GSR62_RS02570	ENOG4105DC7	peptidase M24
GSR62_RS02575	ENOG4105ETE	Transcriptional regulator (LacI family
GSR62_RS02585	ENOG4105CDY	transcriptional regulatory protein
GSR62_RS02600	ENOG4105D7Q	type ii secretion system
GSR62_RS02635	ENOG4105C85	amino acid
GSR62_RS02640	ENOG4105MMD	transcriptional regulator
GSR62_RS02645	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
GSR62_RS02655	ENOG4105DQR	SNARE associated Golgi
GSR62_RS02660	ENOG4105CAY	ferredoxin--nadp reductase
GSR62_RS02795	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
GSR62_RS02805	ENOG4105C8T	Leucyl-tRNA synthetase
GSR62_RS02810	ENOG4105C85	amino acid
GSR62_RS02825	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
GSR62_RS02830	ENOG4107QSE	Dipeptidase
GSR62_RS02865	ENOG4105CUB	amino acid
GSR62_RS02875	ENOG4107YZX	Universal stress protein
GSR62_RS02885	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
GSR62_RS02890	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
GSR62_RS02895	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
GSR62_RS02900	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
GSR62_RS02905	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
GSR62_RS02910	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
GSR62_RS02925	ENOG4105CNT	hydrolase family 2
GSR62_RS02930	ENOG4107RBJ	symporter
GSR62_RS02935	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
GSR62_RS02940	ENOG4105CQ4	Transcriptional regulator
GSR62_RS02945	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
GSR62_RS02950	ENOG4105CKN	UDP-glucose-hexose-1-phosphate uridylyltransferase
GSR62_RS02955	ENOG4105DME	alpha-galactosidase
GSR62_RS02965	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
GSR62_RS02975	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
GSR62_RS02985	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
GSR62_RS02990	ENOG4105CHR	reductase
GSR62_RS02995	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
GSR62_RS03005	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
GSR62_RS03010	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
GSR62_RS03015	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
GSR62_RS03025	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
GSR62_RS03030	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
GSR62_RS03035	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
GSR62_RS03040	ENOG4105SFS	phosphoesterase RecJ domain protein
GSR62_RS03045	ENOG4105C1J	atp-dependent rna helicase
GSR62_RS03050	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
GSR62_RS03055	ENOG4105VBH	UPF0297 protein
GSR62_RS03060	ENOG4108Z08	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
GSR62_RS03065	ENOG4105VPH	UPF0473 protein
GSR62_RS03080	ENOG4105C98	muts2 protein
GSR62_RS03085	ENOG4105K63	Thioredoxin
GSR62_RS03095	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
GSR62_RS03100	ENOG4105M59	Phosphodiesterase, mj0936 family
GSR62_RS03120	ENOG4107SC7	Inner membrane transporter yjeM
GSR62_RS03130	ENOG4105E5Q	amino acid AbC transporter
GSR62_RS03135	ENOG4105CDA	abc transporter atp-binding protein
GSR62_RS03145	ENOG4105C6X	Major Facilitator
GSR62_RS03165	ENOG4105DG6	mannose-6-phosphate isomerase
GSR62_RS03170	ENOG4105F1K	Glutamine amidotransferase
GSR62_RS03175	ENOG4105DMS	mur ligase
GSR62_RS03180	ENOG4107104	thymidine kinase
GSR62_RS03185	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
GSR62_RS03190	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
GSR62_RS03195	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
GSR62_RS03200	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
GSR62_RS03205	ENOG4107RFS	it plays a direct role in the translocation of protons across the membrane (By similarity)
GSR62_RS03210	ENOG4105WS6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
GSR62_RS03215	ENOG4107ZFM	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
GSR62_RS03220	ENOG4107YZM	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
GSR62_RS03225	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
GSR62_RS03230	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
GSR62_RS03240	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
GSR62_RS03250	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
GSR62_RS03255	ENOG4105DFF	Rod shape-determining protein mreb
GSR62_RS03260	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
GSR62_RS03275	ENOG41080E8	Transcriptional regulator, Spx MgsR family
GSR62_RS03290	ENOG4105JRK	feS assembly protein SufD
GSR62_RS03295	ENOG4105C9B	Cysteine desulfurase
GSR62_RS03300	ENOG4108UNV	SUF system FeS assembly protein, NifU family
GSR62_RS03305	ENOG4105DIW	FeS assembly protein SUFB
GSR62_RS03335	ENOG4105E5D	amino acid
GSR62_RS03350	ENOG4105CPF	Cell wall formation (By similarity)
GSR62_RS03360	ENOG4108R3E	Dna-3-methyladenine glycosylase i
GSR62_RS03365	ENOG4107YZX	Universal stress protein
GSR62_RS03375	ENOG4105D1H	recombination factor protein RarA
GSR62_RS03380	ENOG4105D9M	gamma-glutamylcysteine synthetase
GSR62_RS03390	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
GSR62_RS03400	ENOG4107BJW	polysaccharide deacetylase
GSR62_RS03415	ENOG4105DGY	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization (By similarity)
GSR62_RS03420	ENOG4105C3J	Cysteine desulfurase
GSR62_RS03425	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
GSR62_RS03430	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
GSR62_RS03435	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
GSR62_RS03445	ENOG4105W5Q	DNA repair protein (RadC
GSR62_RS03455	ENOG4105DFF	Rod shape-determining protein mreb
GSR62_RS03470	ENOG4107YDG	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
GSR62_RS03475	ENOG4107QMS	site-determining protein
GSR62_RS03480	ENOG4105E5Q	amino acid AbC transporter
GSR62_RS03485	ENOG4105CDA	abc transporter atp-binding protein
GSR62_RS03490	ENOG4105E89	ABC transporter
GSR62_RS03495	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
GSR62_RS03515	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
GSR62_RS03525	ENOG4105CJN	penicillin-binding protein
GSR62_RS03530	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
GSR62_RS03535	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
GSR62_RS03540	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
GSR62_RS03560	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
GSR62_RS03570	ENOG4105DBK	s4 domain protein
GSR62_RS03580	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
GSR62_RS03595	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
GSR62_RS03600	ENOG4105C3J	Cysteine desulfurase
GSR62_RS03610	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
GSR62_RS03615	ENOG4105CVJ	phosphoglycerate mutase
GSR62_RS03625	ENOG4105C7H	Helicase, RecD TraA family
GSR62_RS03630	ENOG4105CBD	Diacylglycerol kinase
GSR62_RS03650	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
GSR62_RS03665	ENOG4105ECY	inositol monophosphatase
GSR62_RS03670	ENOG4105CI3	gtp-binding protein typa
GSR62_RS03675	ENOG4105ZPI	UPF0358 protein
GSR62_RS03680	ENOG4105CNI	cell division protein FtsW
GSR62_RS03685	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
GSR62_RS03695	ENOG4105WUC	UPF0298 protein
GSR62_RS03700	ENOG4106H78	methyltransferase
GSR62_RS03705	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
GSR62_RS03715	ENOG4105KQC	Competence protein
GSR62_RS03720	ENOG4108UK2	deaminase
GSR62_RS03725	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
GSR62_RS03730	ENOG4105TQK	DNA polymerase iii, delta' subunit
GSR62_RS03735	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
GSR62_RS03740	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
GSR62_RS03755	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
GSR62_RS03760	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
GSR62_RS03765	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
GSR62_RS03770	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
GSR62_RS03775	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GSR62_RS03780	ENOG4105GR3	Histidine kinase
GSR62_RS03785	ENOG4107XQC	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins (By similarity)
GSR62_RS03790	ENOG410855V	Acylphosphatase
GSR62_RS03800	ENOG4105F99	Hydroxymethylglutaryl-CoA synthase
GSR62_RS03825	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
GSR62_RS03840	ENOG4108UZ3	Transporter
GSR62_RS03855	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
GSR62_RS03860	ENOG4105VJV	50s ribosomal protein L35
GSR62_RS03865	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
GSR62_RS03870	ENOG4108WJV	had superfamily (subfamily IIIa) phosphatase
GSR62_RS03875	ENOG4105CQW	ribosome biogenesis GTPase YqeH
GSR62_RS03885	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
GSR62_RS03890	ENOG4108WF2	Metal Dependent Phosphohydrolase
GSR62_RS03900	ENOG4108D32	Methyltransferase
GSR62_RS03905	ENOG4105CDE	UPF0348 protein
GSR62_RS03915	ENOG41067VY	50S ribosomal protein L32
GSR62_RS03920	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
GSR62_RS03930	ENOG4105E5Q	amino acid AbC transporter
GSR62_RS03935	ENOG4105CDA	abc transporter atp-binding protein
GSR62_RS03940	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
GSR62_RS03945	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GSR62_RS03950	ENOG4105EXC	Acyl-transferase
GSR62_RS03960	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
GSR62_RS03965	ENOG4108IXY	short-chain dehydrogenase reductase
GSR62_RS03975	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
GSR62_RS03980	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
GSR62_RS03985	ENOG4107ZYR	domain protein
GSR62_RS03995	ENOG4108IQD	Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp (By similarity)
GSR62_RS04000	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
GSR62_RS04005	ENOG4105X96	Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Activated D-alanyl-Dcp donates its D-alanyl substituent to membrane-associated LTA (By similarity)
GSR62_RS04010	ENOG4108M4D	D-alanyl-lipoteichoic acid biosynthesis protein DltD
GSR62_RS04020	ENOG4107RF6	penicillin-binding protein
GSR62_RS04025	ENOG4105WDJ	50S ribosomal protein L33
GSR62_RS04030	ENOG4107ZXI	Rhomboid family
GSR62_RS04040	ENOG4105DKQ	ROK family
GSR62_RS04065	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
GSR62_RS04070	ENOG4105CXI	aluminum resistance protein
GSR62_RS04075	ENOG4105KV4	Transcriptional regulator
GSR62_RS04080	ENOG4105C5F	glutamine synthetase
GSR62_RS04100	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
GSR62_RS04105	ENOG4105ZAD	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
GSR62_RS04110	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
GSR62_RS04115	ENOG4105C25	Primosomal protein n'
GSR62_RS04120	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
GSR62_RS04125	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
GSR62_RS04130	ENOG4108ZF3	Phosphatase
GSR62_RS04135	ENOG4105D9P	serine threonine protein kinase
GSR62_RS04160	ENOG4105VB9	50S ribosomal protein l28
GSR62_RS04165	ENOG4108ZAA	Alkaline-shock protein
GSR62_RS04170	ENOG4105DP4	dak2 domain fusion protein ylov
GSR62_RS04175	ENOG4105CB5	ATP-dependent DNA helicase recG
GSR62_RS04180	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
GSR62_RS04185	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
GSR62_RS04190	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
GSR62_RS04195	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
GSR62_RS04200	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
GSR62_RS04205	ENOG4105VBN	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein (By similarity)
GSR62_RS04210	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GSR62_RS04215	ENOG4105K5M	30s ribosomal protein S16
GSR62_RS04220	ENOG4105VB6	UPF0109 protein
GSR62_RS04230	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
GSR62_RS04235	ENOG4107TCE	N-acetyltransferase
GSR62_RS04240	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
GSR62_RS04300	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
GSR62_RS04305	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
GSR62_RS04315	ENOG4105DBI	uridine monophosphokinase
GSR62_RS04340	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
GSR62_RS04345	ENOG4107TVK	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
GSR62_RS04355	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
GSR62_RS04360	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
GSR62_RS04370	ENOG4108RWN	rrna methyltransferase
GSR62_RS04380	ENOG4105DC7	peptidase M24
GSR62_RS04385	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
GSR62_RS04390	ENOG4108ZSR	alkaline shock protein
GSR62_RS04395	ENOG4105M7K	Involved in the transcription termination process (By similarity)
GSR62_RS04400	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
GSR62_RS04405	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
GSR62_RS04410	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
GSR62_RS04420	ENOG4105DX0	Hemolysin A
GSR62_RS04425	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
GSR62_RS04430	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
GSR62_RS04435	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
GSR62_RS04440	ENOG4105VPS	UPF0291 protein
GSR62_RS04445	ENOG4105VXM	UPF0154 protein
GSR62_RS04450	ENOG4105F6E	Acyl-transferase
GSR62_RS04455	ENOG41060K3	Methyltransferase
GSR62_RS04460	ENOG4105VC4	domain protein
GSR62_RS04465	ENOG4105C5I	Dehydrogenase
GSR62_RS04470	ENOG4105CE9	30S ribosomal protein S2
GSR62_RS04475	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
GSR62_RS04485	ENOG4105QNR	S1 RNA binding domain protein
GSR62_RS04490	ENOG4105I3K	Ferric uptake regulator, Fur family
GSR62_RS04505	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
GSR62_RS04510	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
GSR62_RS04515	ENOG4105FE9	pseudouridine synthase
GSR62_RS04520	ENOG4108SAX	Membrane
GSR62_RS04525	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
GSR62_RS04530	ENOG4105T7X	
GSR62_RS04535	ENOG4105C9U	ATP-dependent DNA helicase RecQ
GSR62_RS04545	ENOG4105CAT	Cytidine monophosphate kinase
GSR62_RS04550	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
GSR62_RS04555	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
GSR62_RS04565	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
GSR62_RS04570	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
GSR62_RS04595	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
GSR62_RS04600	ENOG41068YB	TPR repeat-containing protein
GSR62_RS04610	ENOG4108JYZ	YitT family
GSR62_RS04620	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
GSR62_RS04625	ENOG4105C5H	ABC transporter
GSR62_RS04630	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
GSR62_RS04635	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
GSR62_RS04645	ENOG41090WU	lipolytic protein G-D-S-L family
GSR62_RS04675	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
GSR62_RS04680	ENOG4105C79	DNA protecting protein DprA
GSR62_RS04685	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
GSR62_RS04690	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
GSR62_RS04695	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GSR62_RS04700	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
GSR62_RS04705	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
GSR62_RS04715	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
GSR62_RS04725	ENOG4105CUR	5'-nucleotidase, lipoprotein e(p4) family
GSR62_RS04740	ENOG4105C3F	Signal peptidase i
GSR62_RS04750	ENOG4105EPR	degv family
GSR62_RS04755	ENOG4105F23	Fibronectin-binding protein
GSR62_RS04760	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GSR62_RS04765	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GSR62_RS04815	ENOG4105CHM	Aminotransferase
GSR62_RS04820	ENOG4105VKD	bioY protein
GSR62_RS04830	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
GSR62_RS04835	ENOG4105DND	Transcriptional regulator
GSR62_RS04840	ENOG4108KGH	TRANSCRIPTIONal
GSR62_RS04845	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
GSR62_RS04850	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
GSR62_RS04855	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
GSR62_RS04860	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
GSR62_RS04865	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
GSR62_RS04870	ENOG4105CD3	dihydroorotase
GSR62_RS04875	ENOG4105CXT	aspartate transcarbamylase
GSR62_RS04885	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
GSR62_RS04890	ENOG4105C34	Pseudouridine synthase
GSR62_RS04895	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
GSR62_RS04900	ENOG4105CKU	formyltetrahydrofolate synthetase
GSR62_RS04910	ENOG4105VND	Ribonuclease
GSR62_RS04915	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
GSR62_RS04925	ENOG4105XWG	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation (By similarity)
GSR62_RS04930	ENOG4108UKS	UPF0398 protein
GSR62_RS04935	ENOG4108UI2	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation (By similarity)
GSR62_RS04940	ENOG4105BZ4	penicillin-binding protein
GSR62_RS04950	ENOG4105CSM	endonuclease III
GSR62_RS04960	ENOG4105C5S	asparaginyl-tRNA synthetase
GSR62_RS04965	ENOG4105CHM	Aminotransferase
GSR62_RS04975	ENOG4105DVT	helicase
GSR62_RS04995	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
GSR62_RS05015	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
GSR62_RS05025	ENOG4105VG1	fes assembly suf system protein
GSR62_RS05030	ENOG4108MXZ	Esterase
GSR62_RS05035	ENOG4108KP7	hydrolase
GSR62_RS05040	ENOG41069HH	4-oxalocrotonate tautomerase
GSR62_RS05045	ENOG4105DZW	Dipeptidase
GSR62_RS05065	ENOG4105YPM	F pilin acetylation protein TraX
GSR62_RS05075	ENOG4105C19	ABC transporter
GSR62_RS05080	ENOG4105EWM	Histidine kinase
GSR62_RS05085	ENOG4105CJZ	response regulator
GSR62_RS05095	ENOG4105CA9	Pyruvate kinase
GSR62_RS05100	ENOG4105CTQ	phosphohexokinase
GSR62_RS05105	ENOG4105C0B	DNA polymerase III (alpha subunit)
GSR62_RS05115	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
GSR62_RS05120	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
GSR62_RS05125	ENOG4105EGD	dinuclear metal center protein, YbgI family
GSR62_RS05135	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GSR62_RS05140	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
GSR62_RS05145	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
GSR62_RS05150	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
GSR62_RS05155	ENOG4108SAY	Involved in DNA repair and RecF pathway recombination (By similarity)
GSR62_RS05160	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
GSR62_RS05165	ENOG4107YR5	Diacylglycerol kinase
GSR62_RS05170	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
GSR62_RS05175	ENOG4105C9A	Phoh family
GSR62_RS05180	ENOG4105KTH	gatB Yqey
GSR62_RS05185	ENOG4105VCC	30S ribosomal protein S21
GSR62_RS05190	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
GSR62_RS05195	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
GSR62_RS05200	ENOG4105K64	Glycosyl transferase, family 2
GSR62_RS05210	ENOG4105GH9	galactofuranosyltransferase
GSR62_RS05220	ENOG4105C9M	aspartyl-trna synthetase
GSR62_RS05225	ENOG4105CUT	histidyl-tRNA synthetase
GSR62_RS05230	ENOG4105VTR	Integrase
GSR62_RS05325	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
GSR62_RS05350	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
GSR62_RS05355	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
GSR62_RS05360	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
GSR62_RS05380	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
GSR62_RS05385	ENOG4105CFG	Acts as a chaperone (By similarity)
GSR62_RS05395	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
GSR62_RS05400	ENOG4105DTN	riboflavin biosynthesis protein ribF
GSR62_RS05405	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
GSR62_RS05410	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
GSR62_RS05415	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
GSR62_RS05425	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
GSR62_RS05430	ENOG4105CHV	Transcription elongation factor NusA
GSR62_RS05435	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
GSR62_RS05440	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
GSR62_RS05445	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
GSR62_RS05450	ENOG4105DZP	Membrane-associated zinc metalloprotease
GSR62_RS05455	ENOG4105KNE	Phosphatidate cytidylyltransferase
GSR62_RS05460	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
GSR62_RS05465	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
GSR62_RS05470	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
GSR62_RS05475	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
GSR62_RS05480	ENOG4105K46	50S ribosomal protein l27
GSR62_RS05485	ENOG4105X36	(ribosomal) protein
GSR62_RS05490	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
GSR62_RS05495	ENOG4108V16	CRISPR-associated protein
GSR62_RS05510	ENOG4107SFZ	crispr-associated protein
GSR62_RS05545	ENOG4105HUF	DNA protection during starvation protein
GSR62_RS05575	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
GSR62_RS05585	ENOG4108Z40	Transcriptional regulator
GSR62_RS05600	ENOG4105C22	threonyL-tRNA synthetase
GSR62_RS05615	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
GSR62_RS05620	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
GSR62_RS05625	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
GSR62_RS05630	ENOG4105C2M	dna polymerase I
GSR62_RS05635	ENOG4105HFZ	Membrane
GSR62_RS05655	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
GSR62_RS05660	ENOG4105DFU	Cell wall formation (By similarity)
GSR62_RS05685	ENOG4108VDD	TRNA binding domain protein
GSR62_RS05695	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
GSR62_RS05700	ENOG4108V15	phosphotransferase enzyme family
GSR62_RS05715	ENOG4108UW5	maltose o-acetyltransferase
GSR62_RS05720	ENOG4105K59	histidine triad (HIT) protein
GSR62_RS05730	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
GSR62_RS05745	ENOG4105EQI	Metal Dependent Phosphohydrolase
GSR62_RS05750	ENOG4105WZB	UPF0342 protein
GSR62_RS05755	ENOG4105BZ4	penicillin-binding protein
GSR62_RS05760	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
GSR62_RS05770	ENOG4105C75	arginyL-tRNA synthetase
GSR62_RS05795	ENOG4105DC1	bifunctional purine biosynthesis protein purh
GSR62_RS05805	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
GSR62_RS05810	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
GSR62_RS05815	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
GSR62_RS05820	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
GSR62_RS05825	ENOG4105VR9	phosphoribosylformylglycinamidine synthase
GSR62_RS05850	ENOG4105C83	adenylosuccinate lyase
GSR62_RS05855	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
GSR62_RS05860	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
GSR62_RS05865	ENOG4105DFH	Transport of potassium into the cell (By similarity)
GSR62_RS05870	ENOG4105ZMH	deoxynucleoside kinase
GSR62_RS05875	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
GSR62_RS05880	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
GSR62_RS05885	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
GSR62_RS05895	ENOG4105CHR	reductase
GSR62_RS05910	ENOG4105CNU	cell division protein FtsK
GSR62_RS05920	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
GSR62_RS05935	ENOG4107SJ1	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (By similarity)
GSR62_RS05945	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
GSR62_RS05950	ENOG4106N3A	copper homeostasis protein cutc
GSR62_RS05960	ENOG4105CJW	magnesium transporter
GSR62_RS05965	ENOG4105EMS	pseudouridine synthase
GSR62_RS05970	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
GSR62_RS05995	ENOG4108SQ7	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
GSR62_RS06000	ENOG41090SU	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity)
GSR62_RS06005	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
GSR62_RS06010	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
GSR62_RS06015	ENOG4108UIC	UPF0340 protein
GSR62_RS06020	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
GSR62_RS06025	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
GSR62_RS06030	ENOG4105XZU	Preprotein translocase, subunit SecG
GSR62_RS06040	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
GSR62_RS06045	ENOG4105CP7	Triose-phosphate isomerase
GSR62_RS06050	ENOG4105BZA	Phosphoglycerate kinase
GSR62_RS06055	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
GSR62_RS06065	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GSR62_RS06080	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
GSR62_RS06090	ENOG4105CIE	May be required for sporulation (By similarity)
GSR62_RS06095	ENOG4105CHW	UPF0052 protein
GSR62_RS06100	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
GSR62_RS06105	ENOG4105EJQ	L-serine dehydratase
GSR62_RS06115	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
GSR62_RS06120	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
GSR62_RS06125	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
GSR62_RS06135	ENOG4105C3M	thioredoxin reductase
GSR62_RS06140	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
GSR62_RS06145	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
GSR62_RS06150	ENOG41086DT	Membrane protein of unknown function
GSR62_RS06160	ENOG4105BZU	Histidine kinase
GSR62_RS06165	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
GSR62_RS06175	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
GSR62_RS06180	ENOG4105CAK	Cell division ATP-binding protein ftsE
GSR62_RS06185	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
GSR62_RS06190	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
GSR62_RS06200	ENOG41081UC	Inherit from COG: Competence protein
GSR62_RS06210	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
GSR62_RS06215	ENOG4105ESV	Glycosyl transferase, family 4
GSR62_RS06220	ENOG4105C0X	amino acid
GSR62_RS06225	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
GSR62_RS06230	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
GSR62_RS06235	ENOG4108TYN	CAAX amino terminal protease family protein
GSR62_RS06240	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
GSR62_RS06245	ENOG4105C5H	ABC transporter
GSR62_RS06250	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
GSR62_RS06260	ENOG41072GX	Peptidase M22 Glycoprotease
GSR62_RS06265	ENOG4105HDK	L-asparaginase
GSR62_RS06275	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
GSR62_RS06280	ENOG41063V3	Involved in initiation control of chromosome replication (By similarity)
GSR62_RS06285	ENOG4105FA2	dna polymerase iii
GSR62_RS06290	ENOG4105X0R	protein from nitrogen regulatory protein P-II
GSR62_RS06295	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
GSR62_RS06305	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
GSR62_RS06310	ENOG410816I	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
GSR62_RS06315	ENOG4105C6E	dna polymerase iii
GSR62_RS06325	ENOG4108Z6B	deaminase
GSR62_RS06330	ENOG4107Y49	methyltransferase
GSR62_RS06335	ENOG4105CS2	ec 3.2.1.21
GSR62_RS06340	ENOG4105KWG	Pfam:DUF1696
GSR62_RS06360	ENOG4105EE0	oxidoreductase
GSR62_RS06370	ENOG4108M15	ABC transporter
GSR62_RS06380	ENOG4105ZT7	DNA-entry nuclease
GSR62_RS06385	ENOG4105CU9	asparagine synthetase A
GSR62_RS06395	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
GSR62_RS06400	ENOG4108ZMX	Domain of unknown function (DU1801)
GSR62_RS06435	ENOG4105EHG	Permease protein
GSR62_RS06440	ENOG4105DQ5	transport system permease protein
GSR62_RS06450	ENOG4105E0A	ABC, transporter
GSR62_RS06490	ENOG4105IJJ	transcriptional regulator, crp fnr family
GSR62_RS06495	ENOG4105DZR	Type I site-specific deoxyribonuclease
GSR62_RS06525	ENOG4105CVR	type I restriction-modification system
GSR62_RS06570	ENOG4105C2M	dna polymerase I
GSR62_RS06625	ENOG4105CAR	Terminase, large subunit
GSR62_RS06630	ENOG4105EFC	phage portal protein HK97 family
GSR62_RS06690	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
GSR62_RS06710	ENOG4105D1H	recombination factor protein RarA
GSR62_RS06715	ENOG4105CPQ	Dehydrogenase
GSR62_RS06725	ENOG4105CBD	Diacylglycerol kinase
GSR62_RS06730	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
GSR62_RS06735	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
GSR62_RS06740	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
GSR62_RS06750	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
GSR62_RS06755	ENOG4105C4R	Atp-dependent dna helicase
GSR62_RS06760	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
GSR62_RS06770	ENOG4108UPS	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity)
GSR62_RS06775	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
GSR62_RS06790	ENOG4105C6K	Malic enzyme
GSR62_RS06805	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
GSR62_RS06810	ENOG4107BMA	Transglycosylase associated protein
GSR62_RS06820	ENOG4105VBF	alkaline shock protein
GSR62_RS06850	ENOG41082DI	50s ribosomal protein l31
GSR62_RS06855	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
GSR62_RS06860	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
GSR62_RS06870	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
GSR62_RS06875	ENOG4108Z1Y	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling (By similarity)
GSR62_RS06885	ENOG4105DCI	Phosphohydrolase
GSR62_RS06910	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
GSR62_RS06915	ENOG4105KJF	protein tyrosine phosphatase
GSR62_RS06920	ENOG4105C5H	ABC transporter
GSR62_RS06935	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
GSR62_RS06940	ENOG4105VTR	Integrase
GSR62_RS06945	ENOG4108IMY	Transcriptional regulator
GSR62_RS06995	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
GSR62_RS07000	ENOG4105DFT	pur operon repressor
GSR62_RS07005	ENOG4105CDH	Citrulline--aspartate ligase
GSR62_RS07010	ENOG4105CH7	arginosuccinase
GSR62_RS07015	ENOG4105BZW	Glycerate kinase
GSR62_RS07020	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
GSR62_RS07030	ENOG4105DF9	Lipoate-protein, ligase
GSR62_RS07050	ENOG4107RUY	(E1 component), alpha subunit
GSR62_RS07055	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
GSR62_RS07060	ENOG4105W42	Veg protein
GSR62_RS07065	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
GSR62_RS07075	ENOG4105F8V	Hydrolase, tatD family
GSR62_RS07080	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
GSR62_RS07100	ENOG4105MYU	Immunoglobulin A1 protease
GSR62_RS07105	ENOG4105MYU	Immunoglobulin A1 protease
GSR62_RS07110	ENOG4105MYU	Immunoglobulin A1 protease
GSR62_RS07115	ENOG4105MYU	Immunoglobulin A1 protease
GSR62_RS07150	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
GSR62_RS07155	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
GSR62_RS07160	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
GSR62_RS07170	ENOG4105EEM	helicase
GSR62_RS07225	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
GSR62_RS07230	ENOG4105G5W	regulator Fur family
GSR62_RS07235	ENOG4107K5X	Membrane-bound metal-dependent hydrolase
GSR62_RS07245	ENOG4107RFY	SbcCD D subunit
GSR62_RS07255	ENOG4108YZM	Toxic component of a toxin-antitoxin (TA) module (By similarity)
GSR62_RS07265	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
GSR62_RS07270	ENOG41082V8	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
GSR62_RS07280	ENOG4107QR9	Iron-sulfur cluster binding protein
GSR62_RS07285	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
GSR62_RS07290	ENOG4105CEP	NADH dehydrogenase
GSR62_RS07305	ENOG4108JJ8	(ABC) transporter
GSR62_RS07310	ENOG4108JJ9	ABC, transporter
GSR62_RS07315	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
GSR62_RS07320	ENOG4105C4M	(Ubiquinol oxidase) subunit I
GSR62_RS07335	ENOG4105C1J	atp-dependent rna helicase
GSR62_RS07340	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
GSR62_RS07345	ENOG4105D0M	Protease HtpX homolog
GSR62_RS07350	ENOG4108V0P	LemA family
GSR62_RS07375	ENOG4105BZ1	(ABC) transporter
GSR62_RS07400	ENOG4107EFR	Flavocytochrome c
GSR62_RS07425	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
GSR62_RS07430	ENOG4107T5V	SNARE associated Golgi
GSR62_RS07435	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
GSR62_RS07440	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
GSR62_RS07465	ENOG4105C28	cystathionine
GSR62_RS07470	ENOG4105D7V	transposase
GSR62_RS07480	ENOG4105C6T	cysteine synthase
GSR62_RS07495	ENOG4105E5D	amino acid
GSR62_RS07500	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
GSR62_RS07515	ENOG4108JPW	Aminotransferase
GSR62_RS07520	ENOG4105F27	Major Facilitator
GSR62_RS07525	ENOG4108J5H	Homocysteine s-methyltransferase
GSR62_RS07535	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
GSR62_RS07540	ENOG4105CS2	ec 3.2.1.21
GSR62_RS07545	ENOG4108S3Y	transcriptional regulator
GSR62_RS07550	ENOG4108UJD	30S ribosomal protein S9
GSR62_RS07555	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
GSR62_RS07560	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
GSR62_RS07570	ENOG4108JJB	ABC transporter
GSR62_RS07575	ENOG4108JJB	ABC transporter
GSR62_RS07590	ENOG4107QN2	dihydrolipoyl dehydrogenase
GSR62_RS07605	ENOG4108ZT0	50S ribosomal protein l17
GSR62_RS07610	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GSR62_RS07615	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
GSR62_RS07620	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GSR62_RS07625	ENOG41067V7	50S ribosomal protein L36
GSR62_RS07630	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
GSR62_RS07640	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
GSR62_RS07645	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
GSR62_RS07650	ENOG4105VPB	50S ribosomal protein L30
GSR62_RS07655	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
GSR62_RS07660	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
GSR62_RS07665	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
GSR62_RS07670	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
GSR62_RS07675	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
GSR62_RS07680	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GSR62_RS07685	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
GSR62_RS07690	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
GSR62_RS07695	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
GSR62_RS07700	ENOG41082SA	50s ribosomal protein l29
GSR62_RS07705	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
GSR62_RS07710	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
GSR62_RS07715	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
GSR62_RS07720	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
GSR62_RS07725	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GSR62_RS07730	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
GSR62_RS07735	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
GSR62_RS07740	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
GSR62_RS07760	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
GSR62_RS07765	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
GSR62_RS07770	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
GSR62_RS07785	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GSR62_RS07790	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GSR62_RS07830	ENOG4105EXC	Acyl-transferase
GSR62_RS07920	ENOG4105C5H	ABC transporter
GSR62_RS07930	ENOG4105KHA	Glyoxalase Bleomycin resistance protein (Dioxygenase
GSR62_RS07935	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
GSR62_RS07940	ENOG4105KEX	transcriptional regulator, ctsr
GSR62_RS07960	ENOG4107XDY	Nicotinamide Mononucleotide Transporter
GSR62_RS07990	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
GSR62_RS08005	ENOG4105C6N	Formate acetyltransferase
GSR62_RS08010	ENOG4105N2W	Transcriptional regulator
GSR62_RS08025	ENOG4105CPQ	Dehydrogenase
GSR62_RS08050	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
GSR62_RS08065	ENOG4105VTR	Integrase
GSR62_RS08105	ENOG4105ECI	YeeC-like protein
GSR62_RS08110	ENOG4105F6A	helicase
GSR62_RS08115	ENOG4105D85	methylase
GSR62_RS08120	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
GSR62_RS08125	ENOG4105C87	Aminotransferase class I and II
GSR62_RS08130	ENOG4106F5Q	Membrane
GSR62_RS08135	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
GSR62_RS08145	ENOG4105CMR	udp-glucose 4-epimerase
GSR62_RS08150	ENOG4108TZY	GntR Family Transcriptional Regulator
GSR62_RS08160	ENOG4108JJB	ABC transporter
GSR62_RS08175	ENOG4107QRI	Phosphoketolase
GSR62_RS08180	ENOG4105CVJ	phosphoglycerate mutase
GSR62_RS08190	ENOG4105C59	p-type ATPase
GSR62_RS08205	ENOG4105E2Y	ABC, transporter
GSR62_RS08225	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
GSR62_RS08230	ENOG4105CI1	PTS System
GSR62_RS08235	ENOG4105CI1	PTS System
GSR62_RS08240	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
GSR62_RS08270	ENOG4105CMT	Dihydroxyacetone kinase
GSR62_RS08275	ENOG4105CMT	Dihydroxyacetone kinase
GSR62_RS08280	ENOG4108UTZ	Dihydroxyacetone kinase
GSR62_RS08285	ENOG4105VDH	Dihydroxyacetone kinase
GSR62_RS08290	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
GSR62_RS08295	ENOG4108HMR	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
GSR62_RS08300	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
GSR62_RS08360	ENOG4105M6F	mutator MutT protein
GSR62_RS08385	ENOG4107R0P	L-ribulose-5-phosphate 4-epimerase
GSR62_RS08410	ENOG4105E98	transcriptional regulator DeoR family
GSR62_RS08450	ENOG4105DU0	nucleoside hydrolase
GSR62_RS08455	ENOG4105D9N	nucleoside
GSR62_RS08460	ENOG4107XGZ	Hydrolase
GSR62_RS08500	ENOG4105CSH	Transporter
GSR62_RS08505	ENOG4108UW5	maltose o-acetyltransferase
GSR62_RS08515	ENOG4105U0F	oligosaccharide H symporter, major facilitator superfamily (MFS)
GSR62_RS08520	ENOG4108HKT	sucrose-6-phosphate hydrolase
GSR62_RS08525	ENOG4105ETE	Transcriptional regulator (LacI family
GSR62_RS08555	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
GSR62_RS08560	ENOG4105CS9	pantothenic acid kinase
GSR62_RS08570	ENOG4105EEM	helicase
GSR62_RS08595	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
GSR62_RS08620	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
GSR62_RS08645	ENOG4105C3G	gtp-binding protein
GSR62_RS08650	ENOG4105VDK	protein, conserved in bacteria
GSR62_RS08655	ENOG4105FA0	parb-like partition protein
GSR62_RS08660	ENOG4107QJE	Chromosome Partitioning Protein
GSR62_RS08665	ENOG410636K	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage (By similarity)
GSR62_RS08670	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
GSR62_RS08720	ENOG4108JJB	ABC transporter
GSR62_RS08725	ENOG4105CC5	ABC transporter
GSR62_RS08740	ENOG4108RG0	uracil-dna glycosylase
GSR62_RS08755	ENOG4108IUK	alpha amylase, catalytic
GSR62_RS08765	ENOG4108IUK	alpha amylase, catalytic
GSR62_RS08770	ENOG4105CG3	alpha amylase, catalytic region
GSR62_RS08780	ENOG4105C5Y	PTS System
GSR62_RS08785	ENOG4108HKT	sucrose-6-phosphate hydrolase
GSR62_RS08790	ENOG4105ETE	Transcriptional regulator (LacI family
GSR62_RS08795	ENOG4105C5H	ABC transporter
GSR62_RS08800	ENOG4105BZ1	(ABC) transporter
GSR62_RS08810	ENOG4105CI1	PTS System
GSR62_RS08840	ENOG4105F3R	pts system mannose fructose sorbose family iid
GSR62_RS08845	ENOG4105ETZ	PTS System
GSR62_RS08855	ENOG4108EQA	pts system
GSR62_RS08865	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GSR62_RS08890	ENOG4105EV1	Ribose uptake protein RbsU
GSR62_RS08895	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
GSR62_RS08905	ENOG4105ETE	Transcriptional regulator (LacI family
GSR62_RS08910	ENOG4107RUE	extracellular solute-binding protein family 1
GSR62_RS08915	ENOG4105D38	putrescine abc transporter
GSR62_RS08920	ENOG4105F38	ABC transporter, permease
GSR62_RS08925	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
GSR62_RS08930	ENOG4107V9H	nitrite transporter
GSR62_RS08940	ENOG4105D3R	alkyl hydroperoxide reductase
GSR62_RS08950	ENOG4107S0N	DJ-1 family
GSR62_RS08955	ENOG4107SUZ	Sodium/hydrogen exchanger family
GSR62_RS08960	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
GSR62_RS08965	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
GSR62_RS08970	ENOG4107URF	beta-phospho-glucomutase
GSR62_RS08980	ENOG4105FKQ	transcriptional regulator
GSR62_RS08990	ENOG4105C59	p-type ATPase
GSR62_RS08995	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
GSR62_RS09000	ENOG4105E90	ABC transporter
GSR62_RS09005	ENOG4108IJ8	ABC transporter
GSR62_RS09010	ENOG4105BZ1	(ABC) transporter
GSR62_RS09015	ENOG4105BZ1	(ABC) transporter
GSR62_RS09020	ENOG4107YCR	Transcriptional regulator, ARSR family
GSR62_RS09030	ENOG4108QG2	Membrane
GSR62_RS09055	ENOG4105K7K	Transcriptional regulator
GSR62_RS09105	ENOG4108Q3X	Transcriptional regulator
GSR62_RS09110	ENOG4105F8D	glycoside hydrolase family 4
GSR62_RS09120	ENOG4105K56	Transcriptional regulator
GSR62_RS09135	ENOG4105C9K	Endothelin-converting enzyme 1
GSR62_RS09145	ENOG4105EEQ	Na H antiporter
GSR62_RS09165	ENOG4108UQV	Membrane
GSR62_RS09175	ENOG4105D1Q	UPF0246 protein
GSR62_RS09210	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
GSR62_RS09215	ENOG4108VMM	UPF0756 membrane protein
GSR62_RS09225	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
GSR62_RS09230	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
GSR62_RS09240	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
GSR62_RS09250	ENOG4105CS2	ec 3.2.1.21
GSR62_RS09255	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
GSR62_RS09305	ENOG4105DA5	(ABC) transporter
GSR62_RS09400	ENOG4107EFR	Flavocytochrome c
GSR62_RS09410	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GSR62_RS09415	ENOG4105M7T	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
GSR62_RS09420	ENOG4105VG0	50S ribosomal protein l34