locus-tag	class	description
LLCC_RS00010	COG0358	DNA primase activity
LLCC_RS00115	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LLCC_RS00120	COG0483	inositol monophosphate 1-phosphatase activity
LLCC_RS00125	COG4476	Belongs to the UPF0223 family
LLCC_RS00130	COG1393	Belongs to the ArsC family
LLCC_RS00135	COG4474	Belongs to the UPF0398 family
LLCC_RS00155	COG1705	Flagellar rod assembly protein muramidase FlgJ
LLCC_RS00155	COG1388	LysM domain
LLCC_RS00170	COG3883	PFAM NLP P60 protein
LLCC_RS00170	COG0791	NLP P60 protein
LLCC_RS00175	COG1104	cysteine desulfurase activity
LLCC_RS00205	COG2169	Transcriptional regulator
LLCC_RS00210	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LLCC_RS00220	COG0776	regulation of translation
LLCC_RS00230	COG1472	Belongs to the glycosyl hydrolase 3 family
LLCC_RS00235	COG2755	lipolytic protein G-D-S-L family
LLCC_RS00240	COG1307	EDD domain protein, DegV family
LLCC_RS00245	COG1272	protein, Hemolysin III
LLCC_RS00250	COG0587	DNA-directed DNA polymerase activity
LLCC_RS00265	COG1428	Deoxynucleoside kinase
LLCC_RS00360	COG0504	CTP synthase activity
LLCC_RS00365	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LLCC_RS00375	COG4720	Psort location CytoplasmicMembrane, score
LLCC_RS00380	COG0351	phosphomethylpyrimidine kinase
LLCC_RS00395	COG1316	TRANSCRIPTIONal
LLCC_RS00405	COG0802	atpase or kinase
LLCC_RS00420	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LLCC_RS00425	COG1554	hydrolase, family 65, central catalytic
LLCC_RS00430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LLCC_RS00430	COG1263	PTS System
LLCC_RS00435	COG1263	PTS System
LLCC_RS00435	COG2190	(PTS) system
LLCC_RS00435	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LLCC_RS00440	COG2188	Transcriptional regulator
LLCC_RS00470	COG3842	ATPase activity
LLCC_RS00475	COG1597	lipid kinase activity
LLCC_RS00495	COG2723	6-phospho-beta-galactosidase activity
LLCC_RS00500	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LLCC_RS00510	COG1447	Phosphotransferase system cellobiose-specific component IIA
LLCC_RS00515	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LLCC_RS00520	COG1737	Transcriptional regulator
LLCC_RS00530	COG0513	Belongs to the DEAD box helicase family
LLCC_RS00540	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LLCC_RS00550	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LLCC_RS00555	COG1304	FMN binding
LLCC_RS00570	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LLCC_RS00575	COG1846	Transcriptional regulator
LLCC_RS00605	COG1774	PSP1 C-terminal conserved region
LLCC_RS00610	COG0470	DNA polymerase III
LLCC_RS00620	COG0745	RESPONSE REGULATOR receiver
LLCC_RS00625	COG5002	protein histidine kinase activity
LLCC_RS00630	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LLCC_RS00650	COG0446	pyridine nucleotide-disulphide oxidoreductase
LLCC_RS00655	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LLCC_RS00660	COG3118	belongs to the thioredoxin family
LLCC_RS00670	COG1363	Peptidase, m42
LLCC_RS00675	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LLCC_RS00690	COG0025	NhaP-type Na H and K H
LLCC_RS00695	COG1764	response to oxidative stress
LLCC_RS00710	COG0301	tRNA thio-modification
LLCC_RS00725	COG0583	DNA-binding transcription factor activity
LLCC_RS00735	COG2855	membrane
LLCC_RS00770	COG0833	amino acid
LLCC_RS00780	COG0564	pseudouridine synthase activity
LLCC_RS00790	COG2357	RelA SpoT domain protein
LLCC_RS00820	COG1113	amino acid transport
LLCC_RS00825	COG1113	amino acid transport
LLCC_RS00830	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LLCC_RS00840	COG0367	asparagine synthase
LLCC_RS00850	COG0513	Belongs to the DEAD box helicase family
LLCC_RS00860	COG4608	Belongs to the ABC transporter superfamily
LLCC_RS00865	COG0444	Belongs to the ABC transporter superfamily
LLCC_RS00870	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LLCC_RS00875	COG0601	transmembrane transport
LLCC_RS00890	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LLCC_RS00900	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LLCC_RS00905	COG0768	penicillin binding
LLCC_RS00910	COG3634	alkyl hydroperoxide reductase activity
LLCC_RS00915	COG0450	alkyl hydroperoxide reductase
LLCC_RS00920	COG0588	phosphoglycerate mutase activity
LLCC_RS00925	COG0346	lactoylglutathione lyase activity
LLCC_RS00930	COG1733	regulation of RNA biosynthetic process
LLCC_RS00935	COG0656	L-ascorbic acid biosynthetic process
LLCC_RS00940	COG2814	Major facilitator Superfamily
LLCC_RS00955	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LLCC_RS00960	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LLCC_RS00965	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LLCC_RS00970	COG1120	ATPase activity
LLCC_RS00995	COG2011	ABC-type metal ion transport system permease component
LLCC_RS01005	COG1464	Belongs to the NlpA lipoprotein family
LLCC_RS01015	COG1464	Belongs to the NlpA lipoprotein family
LLCC_RS01025	COG1464	Belongs to the NlpA lipoprotein family
LLCC_RS01030	COG3859	Proton-coupled thiamine transporter YuaJ
LLCC_RS01035	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LLCC_RS01040	COG1268	BioY protein
LLCC_RS01065	COG4443	Transcriptional Coactivator p15 (PC4)
LLCC_RS01070	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LLCC_RS01075	COG1132	(ABC) transporter
LLCC_RS01080	COG1132	(ABC) transporter
LLCC_RS01090	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LLCC_RS01095	COG1846	Transcriptional regulator
LLCC_RS01115	COG0737	Belongs to the 5'-nucleotidase family
LLCC_RS01120	COG3639	organic phosphonate transmembrane transporter activity
LLCC_RS01190	COG0456	acetyltransferase
LLCC_RS01205	COG5503	Protein of unknown function (DUF1447)
LLCC_RS01225	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LLCC_RS01230	COG3091	SprT-like family
LLCC_RS01235	COG2183	response to ionizing radiation
LLCC_RS01240	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LLCC_RS01260	COG0726	polysaccharide deacetylase
LLCC_RS01285	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LLCC_RS01295	COG1122	ATPase activity
LLCC_RS01330	COG1328	CTP reductase activity
LLCC_RS01350	COG1335	isochorismatase
LLCC_RS01370	COG1854	S-ribosylhomocysteine lyase activity
LLCC_RS01375	COG0673	inositol 2-dehydrogenase activity
LLCC_RS01400	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LLCC_RS01405	COG2081	HI0933 family
LLCC_RS01420	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LLCC_RS01435	COG4690	dipeptidase activity
LLCC_RS01440	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LLCC_RS01445	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
LLCC_RS01450	COG1461	Dihydroxyacetone kinase
LLCC_RS01455	COG2376	Dihydroxyacetone kinase
LLCC_RS01460	COG1309	transcriptional regulator
LLCC_RS01465	COG2376	Dihydroxyacetone kinase
LLCC_RS01480	COG0561	phosphatase activity
LLCC_RS01485	COG0828	Belongs to the bacterial ribosomal protein bS21 family
LLCC_RS01490	COG0789	Transcriptional regulator
LLCC_RS01495	COG0477	Major facilitator Superfamily
LLCC_RS01500	COG1309	transcriptional regulator
LLCC_RS01540	COG2226	methyltransferase
LLCC_RS01545	COG0799	negative regulation of ribosome biogenesis
LLCC_RS01555	COG1713	HD superfamily hydrolase involved in NAD metabolism
LLCC_RS01565	COG1534	Rna-binding protein
LLCC_RS01575	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LLCC_RS01585	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LLCC_RS01590	COG0516	GMP reductase activity
LLCC_RS01590	COG0517	IMP dehydrogenase activity
LLCC_RS01620	COG0562	UDP-galactopyranose mutase
LLCC_RS01625	COG0438	transferase activity, transferring glycosyl groups
LLCC_RS01635	COG0438	transferase activity, transferring glycosyl groups
LLCC_RS01640	COG1216	Glycosyl transferase, family 2
LLCC_RS01670	COG1216	Glycosyl transferase, family 2
LLCC_RS01670	COG1442	glycosyl transferase family 8
LLCC_RS01690	COG1215	transferase activity, transferring glycosyl groups
LLCC_RS01705	COG1088	dTDP-glucose 4,6-dehydratase activity
LLCC_RS01725	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LLCC_RS01735	COG0227	Belongs to the bacterial ribosomal protein bL28 family
LLCC_RS01745	COG1461	Dihydroxyacetone kinase
LLCC_RS01780	COG0142	geranyltranstransferase activity
LLCC_RS01795	COG4470	Protein conserved in bacteria
LLCC_RS01800	COG0737	Belongs to the 5'-nucleotidase family
LLCC_RS01805	COG0756	dUTP diphosphatase activity
LLCC_RS01810	COG2723	6-phospho-beta-galactosidase activity
LLCC_RS01825	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LLCC_RS01830	COG3328	transposase activity
LLCC_RS01845	COG0346	lactoylglutathione lyase activity
LLCC_RS01860	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LLCC_RS01885	COG0154	amidase activity
LLCC_RS01895	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
LLCC_RS01900	COG0436	Aminotransferase
LLCC_RS01925	COG1832	CoA-binding protein
LLCC_RS01930	COG2814	Major facilitator Superfamily
LLCC_RS02000	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LLCC_RS02005	COG1309	transcriptional regulator
LLCC_RS02010	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
LLCC_RS02020	COG0300	oxidoreductase activity
LLCC_RS02030	COG3906	Belongs to the UPF0473 family
LLCC_RS02040	COG4472	Bacterial protein of unknown function (DUF965)
LLCC_RS02045	COG1266	CAAX protease self-immunity
LLCC_RS02060	COG4989	oxidoreductase activity
LLCC_RS02065	COG0230	Belongs to the bacterial ribosomal protein bL34 family
LLCC_RS02070	COG1847	R3H domain protein
LLCC_RS02075	COG0706	membrane insertase activity
LLCC_RS02080	COG0594	ribonuclease P activity
LLCC_RS02125	COG2814	Major facilitator Superfamily
LLCC_RS02130	COG2076	Multidrug Resistance protein
LLCC_RS02160	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LLCC_RS02180	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LLCC_RS02185	COG0653	protein targeting
LLCC_RS02190	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LLCC_RS02200	COG0204	Acyl-transferase
LLCC_RS02205	COG0531	amino acid
LLCC_RS02210	COG1011	Hydrolase
LLCC_RS02235	COG0726	polysaccharide deacetylase
LLCC_RS02240	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LLCC_RS02265	COG0488	(ABC) transporter
LLCC_RS02275	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LLCC_RS02280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LLCC_RS02285	COG1475	DNA binding
LLCC_RS02295	COG2217	Heavy metal translocating P-type atpase
LLCC_RS02300	COG0333	Belongs to the bacterial ribosomal protein bL32 family
LLCC_RS02305	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LLCC_RS02310	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LLCC_RS02315	COG0346	lactoylglutathione lyase activity
LLCC_RS02320	COG0400	carboxylic ester hydrolase activity
LLCC_RS02340	COG4221	oxidoreductase activity
LLCC_RS02360	COG1309	transcriptional regulator
LLCC_RS02365	COG4221	oxidoreductase activity
LLCC_RS02385	COG0488	(ABC) transporter
LLCC_RS02405	COG1764	response to oxidative stress
LLCC_RS02410	COG0180	Tryptophanyl-tRNA synthetase
LLCC_RS02430	COG0584	glycerophosphoryl diester phosphodiesterase
LLCC_RS02435	COG0095	Lipoate-protein ligase
LLCC_RS02450	COG0508	dehydrogenase complex catalyzes the overall conversion of
LLCC_RS02465	COG0436	Aminotransferase
LLCC_RS02475	COG3153	acetyltransferase
LLCC_RS02480	COG0659	secondary active sulfate transmembrane transporter activity
LLCC_RS02490	COG0454	-acetyltransferase
LLCC_RS02535	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LLCC_RS02545	COG2213	PTS system mannitol-specific
LLCC_RS02590	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LLCC_RS02595	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
LLCC_RS02600	COG0037	tRNA processing
LLCC_RS02620	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LLCC_RS02625	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LLCC_RS02640	COG0012	GTP binding
LLCC_RS02665	COG0592	DNA-directed DNA polymerase activity
LLCC_RS02670	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LLCC_RS02705	COG1242	4 iron, 4 sulfur cluster binding
LLCC_RS02710	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
LLCC_RS02715	COG4975	Glucose uptake
LLCC_RS02720	COG1686	Belongs to the peptidase S11 family
LLCC_RS02735	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LLCC_RS02740	COG0049	tRNA binding
LLCC_RS02745	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LLCC_RS02770	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LLCC_RS02775	COG0681	Belongs to the peptidase S26 family
LLCC_RS02785	COG1136	(ABC) transporter
LLCC_RS02795	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LLCC_RS02800	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LLCC_RS02860	COG1266	CAAX protease self-immunity
LLCC_RS02880	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LLCC_RS02895	COG2824	Alkylphosphonate utilization operon protein PhnA
LLCC_RS02900	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LLCC_RS02935	COG1187	pseudouridine synthase activity
LLCC_RS02940	COG1309	transcriptional regulator
LLCC_RS02955	COG0589	response to stress
LLCC_RS02960	COG2814	Major facilitator Superfamily
LLCC_RS02965	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LLCC_RS02975	COG0494	nUDIX hydrolase
LLCC_RS02990	COG3942	CHAP domain
LLCC_RS02990	COG3883	PFAM NLP P60 protein
LLCC_RS02995	COG0367	asparagine synthase
LLCC_RS03005	COG1794	racemase activity, acting on amino acids and derivatives
LLCC_RS03020	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
LLCC_RS03025	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LLCC_RS03035	COG0730	response to heat
LLCC_RS03085	COG2255	four-way junction helicase activity
LLCC_RS03090	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LLCC_RS03095	COG0789	Transcriptional regulator
LLCC_RS03100	COG0174	glutamine synthetase
LLCC_RS03125	COG5484	DNA packaging
LLCC_RS03125	COG3728	DNA packaging
LLCC_RS03210	COG0582	viral genome integration into host DNA
LLCC_RS03220	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
LLCC_RS03220	COG1605	Chorismate mutase
LLCC_RS03225	COG1956	GAF domain-containing protein
LLCC_RS03235	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LLCC_RS03240	COG0833	amino acid
LLCC_RS03250	COG0360	Binds together with S18 to 16S ribosomal RNA
LLCC_RS03255	COG0629	single-stranded DNA binding
LLCC_RS03260	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LLCC_RS03265	COG1408	metallophosphoesterase
LLCC_RS03280	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
LLCC_RS03285	COG1070	Carbohydrate kinase
LLCC_RS03330	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LLCC_RS03365	COG0525	valine-tRNA ligase activity
LLCC_RS03375	COG1733	regulation of RNA biosynthetic process
LLCC_RS03385	COG0702	epimerase
LLCC_RS03425	COG2814	Major facilitator Superfamily
LLCC_RS03430	COG0742	ribosomal rna small subunit methyltransferase
LLCC_RS03440	COG3480	Lon protease (S16) C-terminal proteolytic domain
LLCC_RS03465	COG1012	belongs to the aldehyde dehydrogenase family
LLCC_RS03465	COG1454	alcohol dehydrogenase
LLCC_RS03470	COG2706	6-phosphogluconolactonase activity
LLCC_RS03475	COG0052	Belongs to the universal ribosomal protein uS2 family
LLCC_RS03480	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LLCC_RS03530	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LLCC_RS03530	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LLCC_RS03535	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
LLCC_RS03550	COG0438	transferase activity, transferring glycosyl groups
LLCC_RS03560	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LLCC_RS03575	COG1862	Preprotein translocase
LLCC_RS03580	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LLCC_RS03585	COG4589	Belongs to the CDS family
LLCC_RS03590	COG0750	zinc metalloprotease
LLCC_RS03595	COG0442	prolyl-tRNA aminoacylation
LLCC_RS03600	COG0446	pyridine nucleotide-disulphide oxidoreductase
LLCC_RS03610	COG2176	DNA-directed DNA polymerase activity
LLCC_RS03620	COG1459	type II secretion system
LLCC_RS03625	COG4537	Required for transformation and DNA binding
LLCC_RS03650	COG1846	Transcriptional regulator
LLCC_RS03655	COG0803	Belongs to the bacterial solute-binding protein 9 family
LLCC_RS03655	COG3443	Belongs to the bacterial solute-binding protein 9 family
LLCC_RS03660	COG1121	(ABC) transporter
LLCC_RS03665	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LLCC_RS03675	COG0564	pseudouridine synthase activity
LLCC_RS03690	COG2323	membrane
LLCC_RS03695	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LLCC_RS03700	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
LLCC_RS03700	COG2755	lipolytic protein G-D-S-L family
LLCC_RS03705	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LLCC_RS03715	COG0250	Participates in transcription elongation, termination and antitermination
LLCC_RS03720	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LLCC_RS03730	COG1970	mechanosensitive ion channel activity
LLCC_RS03735	COG0051	transcription antitermination factor activity, RNA binding
LLCC_RS03740	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LLCC_RS03755	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LLCC_RS03760	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LLCC_RS03765	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LLCC_RS03770	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LLCC_RS03775	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LLCC_RS03780	COG0255	Belongs to the universal ribosomal protein uL29 family
LLCC_RS03785	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LLCC_RS03790	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LLCC_RS03795	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LLCC_RS03800	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LLCC_RS03805	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LLCC_RS03815	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LLCC_RS03825	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LLCC_RS03830	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LLCC_RS03835	COG1841	ribosomal large subunit assembly
LLCC_RS03840	COG0200	Binds to the 23S rRNA
LLCC_RS03850	COG0563	adenylate kinase activity
LLCC_RS03855	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LLCC_RS03860	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LLCC_RS03865	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LLCC_RS03870	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LLCC_RS03875	COG0202	RNA polymerase activity
LLCC_RS03880	COG0203	ribosomal protein L17
LLCC_RS03895	COG1216	Glycosyl transferase, family 2
LLCC_RS03920	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
LLCC_RS03930	COG1442	glycosyl transferase family 8
LLCC_RS03930	COG1216	Glycosyl transferase, family 2
LLCC_RS03950	COG4956	integral membrane protein (PIN domain superfamily)
LLCC_RS03995	COG1335	isochorismatase
LLCC_RS04010	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LLCC_RS04015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LLCC_RS04035	COG1266	CAAX protease self-immunity
LLCC_RS04050	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LLCC_RS04060	COG3328	transposase activity
LLCC_RS04095	COG3942	CHAP domain
LLCC_RS04095	COG1705	Flagellar rod assembly protein muramidase FlgJ
LLCC_RS04120	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LLCC_RS04130	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LLCC_RS04145	COG2235	arginine
LLCC_RS04150	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LLCC_RS04170	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LLCC_RS04175	COG0531	amino acid
LLCC_RS04195	COG0783	Belongs to the Dps family
LLCC_RS04205	COG1940	carbohydrate kinase activity
LLCC_RS04245	COG1217	gtp-binding protein TYPA
LLCC_RS04255	COG0827	DNA restriction-modification system
LLCC_RS04260	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LLCC_RS04265	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LLCC_RS04290	COG2996	Protein conserved in bacteria
LLCC_RS04295	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LLCC_RS04300	COG4479	Belongs to the UPF0346 family
LLCC_RS04305	COG1131	(ABC) transporter
LLCC_RS04315	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LLCC_RS04320	COG0081	regulation of translation
LLCC_RS04335	COG0537	adenosine 5'-monophosphoramidase activity
LLCC_RS04345	COG1131	(ABC) transporter
LLCC_RS04440	COG3728	DNA packaging
LLCC_RS04440	COG5484	DNA packaging
LLCC_RS04450	COG0500	methyltransferase
LLCC_RS04465	COG0826	peptidase U32
LLCC_RS04480	COG0667	Aldo Keto reductase
LLCC_RS04505	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LLCC_RS04515	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LLCC_RS04530	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LLCC_RS04540	COG2501	S4 domain
LLCC_RS04545	COG0612	Peptidase, M16
LLCC_RS04550	COG0612	Peptidase, M16
LLCC_RS04555	COG1426	Protein conserved in bacteria
LLCC_RS04560	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LLCC_RS04590	COG0537	adenosine 5'-monophosphoramidase activity
LLCC_RS04600	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LLCC_RS04605	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LLCC_RS04610	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LLCC_RS04620	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LLCC_RS04680	COG3397	chitin binding
LLCC_RS04685	COG3469	chitinase activity
LLCC_RS04700	COG3479	Phenolic acid decarboxylase
LLCC_RS04710	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LLCC_RS04710	COG0072	phenylalanine-tRNA ligase activity
LLCC_RS04720	COG1388	LysM domain
LLCC_RS04720	COG3584	3D domain protein
LLCC_RS04725	COG1162	GTPase activity
LLCC_RS04750	COG3481	metal-dependent phosphohydrolase, HD sub domain
LLCC_RS04780	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
LLCC_RS04790	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LLCC_RS04805	COG1914	H( )-stimulated, divalent metal cation uptake system
LLCC_RS04820	COG2860	membrane
LLCC_RS04880	COG0191	fructose-bisphosphate aldolase activity
LLCC_RS04885	COG3942	CHAP domain
LLCC_RS04885	COG1705	Flagellar rod assembly protein muramidase FlgJ
LLCC_RS04905	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
LLCC_RS04905	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
LLCC_RS04910	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LLCC_RS04920	COG0363	glucosamine-6-phosphate deaminase activity
LLCC_RS04930	COG0194	GDP metabolic process
LLCC_RS04940	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LLCC_RS04970	COG2261	transglycosylase associated protein
LLCC_RS05110	COG0463	Glycosyl transferase, family 2
LLCC_RS05120	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LLCC_RS05120	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LLCC_RS05125	COG0631	protein serine/threonine phosphatase activity
LLCC_RS05130	COG0515	serine threonine protein kinase
LLCC_RS05130	COG2815	serine threonine protein kinase
LLCC_RS05135	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LLCC_RS05140	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LLCC_RS05150	COG0494	nUDIX hydrolase
LLCC_RS05160	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LLCC_RS05200	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LLCC_RS05215	COG1307	EDD domain protein, DegV family
LLCC_RS05220	COG0849	cell division
LLCC_RS05225	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LLCC_RS05230	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LLCC_RS05235	COG1799	cell septum assembly
LLCC_RS05245	COG2302	S4 RNA-binding domain
LLCC_RS05250	COG3599	regulation of cell shape
LLCC_RS05255	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LLCC_RS05270	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LLCC_RS05280	COG1104	cysteine desulfurase activity
LLCC_RS05285	COG0589	response to stress
LLCC_RS05290	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LLCC_RS05310	COG1045	serine acetyltransferase
LLCC_RS05325	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
LLCC_RS05360	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LLCC_RS05365	COG0291	Belongs to the bacterial ribosomal protein bL35 family
LLCC_RS05370	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LLCC_RS05375	COG0444	Belongs to the ABC transporter superfamily
LLCC_RS05390	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LLCC_RS05405	COG1199	ATP-dependent helicase activity
LLCC_RS05405	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LLCC_RS05415	COG0436	Aminotransferase
LLCC_RS05445	COG1564	THIamine pyrophosphokinase
LLCC_RS05455	COG1113	amino acid transport
LLCC_RS05460	COG2827	Endonuclease containing a URI domain
LLCC_RS05470	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LLCC_RS05475	COG1573	uracil-dna glycosylase
LLCC_RS05505	COG0628	permease
LLCC_RS05510	COG1253	flavin adenine dinucleotide binding
LLCC_RS05515	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LLCC_RS05520	COG1227	inorganic diphosphatase activity
LLCC_RS05530	COG2195	Cleaves the N-terminal amino acid of tripeptides
LLCC_RS05550	COG0514	ATP-dependent DNA helicase (RecQ)
LLCC_RS05570	COG2244	polysaccharide biosynthetic process
LLCC_RS05590	COG1396	sequence-specific DNA binding
LLCC_RS05615	COG0765	amino acid transport
LLCC_RS05620	COG1126	abc transporter atp-binding protein
LLCC_RS05625	COG4862	establishment of competence for transformation
LLCC_RS05630	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LLCC_RS05640	COG0719	Fe-S assembly protein
LLCC_RS05645	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LLCC_RS05660	COG0719	Fe-S assembly protein
LLCC_RS05665	COG4842	Belongs to the WXG100 family
LLCC_RS05690	COG1268	BioY protein
LLCC_RS05705	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LLCC_RS05725	COG4152	abc transporter atp-binding protein
LLCC_RS05765	COG0356	it plays a direct role in the translocation of protons across the membrane
LLCC_RS05770	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LLCC_RS05780	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LLCC_RS05790	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LLCC_RS05825	COG1126	abc transporter atp-binding protein
LLCC_RS05830	COG0765	amino acid transport
LLCC_RS05855	COG4493	Belongs to the UPF0637 family
LLCC_RS05875	COG1136	(ABC) transporter
LLCC_RS05880	COG0577	efflux transmembrane transporter activity
LLCC_RS05895	COG0745	RESPONSE REGULATOR receiver
LLCC_RS05905	COG0287	Prephenate dehydrogenase
LLCC_RS05920	COG0077	Prephenate dehydratase
LLCC_RS05925	COG0406	alpha-ribazole phosphatase activity
LLCC_RS05930	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LLCC_RS05935	COG0268	Binds directly to 16S ribosomal RNA
LLCC_RS05945	COG1597	lipid kinase activity
LLCC_RS05955	COG1396	sequence-specific DNA binding
LLCC_RS06035	COG0670	Belongs to the BI1 family
LLCC_RS06040	COG1556	Lactate utilization protein
LLCC_RS06050	COG0247	lactate metabolic process
LLCC_RS06055	COG0561	phosphatase activity
LLCC_RS06060	COG2252	PERMEase
LLCC_RS06085	COG4122	O-methyltransferase activity
LLCC_RS06090	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LLCC_RS06115	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LLCC_RS06130	COG0573	inorganic phosphate transmembrane transporter activity
LLCC_RS06135	COG0581	inorganic phosphate transmembrane transporter activity
LLCC_RS06140	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LLCC_RS06145	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LLCC_RS06150	COG0704	Plays a role in the regulation of phosphate uptake
LLCC_RS06175	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LLCC_RS06195	COG3716	PTS system mannose fructose sorbose family IID component
LLCC_RS06200	COG3715	PTS system
LLCC_RS06250	COG1609	Transcriptional regulator
LLCC_RS06255	COG0745	RESPONSE REGULATOR receiver
LLCC_RS06260	COG5002	protein histidine kinase activity
LLCC_RS06275	COG2723	6-phospho-beta-galactosidase activity
LLCC_RS06325	COG0741	lytic transglycosylase activity
LLCC_RS06340	COG0572	uridine kinase
LLCC_RS06345	COG0280	phosphate acetyltransferase
LLCC_RS06355	COG0561	phosphatase activity
LLCC_RS06360	COG1674	ftsk spoiiie
LLCC_RS06370	COG1466	dna polymerase III delta subunit
LLCC_RS06375	COG3599	regulation of cell shape
LLCC_RS06385	COG0116	Belongs to the methyltransferase superfamily
LLCC_RS06395	COG0006	proline dipeptidase activity
LLCC_RS06400	COG1609	Transcriptional regulator
LLCC_RS06410	COG1286	toxin biosynthetic process
LLCC_RS06420	COG3118	belongs to the thioredoxin family
LLCC_RS06440	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LLCC_RS06445	COG1609	Transcriptional regulator
LLCC_RS06455	COG1869	D-ribose catabolic process
LLCC_RS06470	COG1879	ABC-type sugar transport system periplasmic component
LLCC_RS06480	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LLCC_RS06495	COG3561	AntA/AntB antirepressor
LLCC_RS06525	COG4712	double-strand break repair protein
LLCC_RS06590	COG0756	dUTP diphosphatase activity
LLCC_RS06615	COG3328	transposase activity
LLCC_RS06750	COG0741	lytic transglycosylase activity
LLCC_RS06750	COG1388	LysM domain
LLCC_RS06795	COG0477	Major facilitator Superfamily
LLCC_RS06800	COG1802	Transcriptional regulator
LLCC_RS06810	COG1312	Catalyzes the dehydration of D-mannonate
LLCC_RS06835	COG0800	Aldolase
LLCC_RS06840	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LLCC_RS06870	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LLCC_RS06885	COG1285	pathogenesis
LLCC_RS06900	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LLCC_RS06940	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LLCC_RS06945	COG1230	cation diffusion facilitator family transporter
LLCC_RS06975	COG0505	Belongs to the CarA family
LLCC_RS07015	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LLCC_RS07025	COG3328	transposase activity
LLCC_RS07035	COG1705	Flagellar rod assembly protein muramidase FlgJ
LLCC_RS07035	COG3942	CHAP domain
LLCC_RS07045	COG0254	rRNA binding
LLCC_RS07055	COG0745	RESPONSE REGULATOR receiver
LLCC_RS07060	COG5002	protein histidine kinase activity
LLCC_RS07065	COG0004	ammonium transporteR
LLCC_RS07070	COG0347	Belongs to the P(II) protein family
LLCC_RS07075	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LLCC_RS07080	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LLCC_RS07090	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LLCC_RS07105	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LLCC_RS07115	COG0363	glucosamine-6-phosphate deaminase activity
LLCC_RS07120	COG3425	synthase
LLCC_RS07125	COG0183	Belongs to the thiolase family
LLCC_RS07135	COG0228	four-way junction DNA binding
LLCC_RS07140	COG1837	Belongs to the UPF0109 family
LLCC_RS07160	COG0336	Belongs to the RNA methyltransferase TrmD family
LLCC_RS07170	COG1307	EDD domain protein, DegV family
LLCC_RS07175	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
LLCC_RS07185	COG0617	tRNA 3'-terminal CCA addition
LLCC_RS07190	COG4690	dipeptidase activity
LLCC_RS07200	COG0371	Dehydrogenase
LLCC_RS07210	COG0488	(ABC) transporter
LLCC_RS07220	COG0673	inositol 2-dehydrogenase activity
LLCC_RS07225	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LLCC_RS07230	COG0167	dihydroorotate dehydrogenase activity
LLCC_RS07250	COG1609	Transcriptional regulator
LLCC_RS07255	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LLCC_RS07260	COG0698	ribose 5-phosphate isomerase
LLCC_RS07265	COG2723	6-phospho-beta-galactosidase activity
LLCC_RS07295	COG1846	Transcriptional regulator
LLCC_RS07300	COG0477	Major facilitator Superfamily
LLCC_RS07305	COG4221	oxidoreductase activity
LLCC_RS07315	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LLCC_RS07370	COG0542	response to heat
LLCC_RS07375	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LLCC_RS07380	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LLCC_RS07405	COG0138	bifunctional purine biosynthesis protein purh
LLCC_RS07410	COG1011	Hydrolase
LLCC_RS07425	COG0151	Belongs to the GarS family
LLCC_RS07435	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LLCC_RS07450	COG2115	Belongs to the xylose isomerase family
LLCC_RS07470	COG0519	Catalyzes the synthesis of GMP from XMP
LLCC_RS07470	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LLCC_RS07475	COG4209	transmembrane transport
LLCC_RS07480	COG0395	ABC-type sugar transport system, permease component
LLCC_RS07485	COG1653	transport
LLCC_RS07510	COG1846	Transcriptional regulator
LLCC_RS07515	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LLCC_RS07540	COG0735	belongs to the Fur family
LLCC_RS07565	COG0778	Nitroreductase
LLCC_RS07570	COG3759	membrane
LLCC_RS07575	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LLCC_RS07580	COG0512	Glutamine amidotransferase of anthranilate synthase
LLCC_RS07585	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LLCC_RS07610	COG0134	indole-3-glycerol-phosphate synthase activity
LLCC_RS07615	COG0135	phosphoribosylanthranilate isomerase activity
LLCC_RS07635	COG3711	transcriptional antiterminator
LLCC_RS07640	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LLCC_RS07640	COG1263	PTS System
LLCC_RS07640	COG2190	(PTS) system
LLCC_RS07645	COG2723	6-phospho-beta-galactosidase activity
LLCC_RS07655	COG4175	Glycine betaine
LLCC_RS07655	COG3448	diguanylate cyclase activity
LLCC_RS07690	COG3969	phosphoadenosine phosphosulfate
LLCC_RS07710	COG3223	Belongs to the PsiE family
LLCC_RS07715	COG1072	(Pantothenic acid kinase))
LLCC_RS07720	COG2813	Specifically methylates the guanine in position
LLCC_RS07735	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LLCC_RS07745	COG1744	ABC transporter substrate-binding protein PnrA-like
LLCC_RS07750	COG2188	Transcriptional regulator
LLCC_RS07770	COG0745	RESPONSE REGULATOR receiver
LLCC_RS07775	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
LLCC_RS07830	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LLCC_RS07840	COG0386	Belongs to the glutathione peroxidase family
LLCC_RS07875	COG0582	viral genome integration into host DNA
LLCC_RS07880	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LLCC_RS07940	COG2189	Belongs to the N(4) N(6)-methyltransferase family
LLCC_RS07970	COG0756	dUTP diphosphatase activity
LLCC_RS08040	COG0740	serine-type endopeptidase activity
LLCC_RS08130	COG5263	repeat protein
LLCC_RS08130	COG5632	N-Acetylmuramoyl-L-alanine amidase
LLCC_RS08165	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LLCC_RS08170	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LLCC_RS08175	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LLCC_RS08180	COG1187	pseudouridine synthase activity
LLCC_RS08215	COG1175	transmembrane transport
LLCC_RS08250	COG2188	Transcriptional regulator
LLCC_RS08255	COG2814	Major facilitator Superfamily
LLCC_RS08270	COG0167	dihydroorotate dehydrogenase activity
LLCC_RS08290	COG0142	geranyltranstransferase activity
LLCC_RS08310	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LLCC_RS08320	COG3853	Toxic anion resistance protein (TelA)
LLCC_RS08335	COG0205	6-phosphofructokinase activity
LLCC_RS08340	COG0469	pyruvate kinase activity
LLCC_RS08345	COG0039	L-malate dehydrogenase activity
LLCC_RS08350	COG1079	Belongs to the binding-protein-dependent transport system permease family
LLCC_RS08355	COG4603	Belongs to the binding-protein-dependent transport system permease family
LLCC_RS08360	COG3845	ABC transporter
LLCC_RS08365	COG2226	methyltransferase
LLCC_RS08370	COG1293	RNA-binding protein homologous to eukaryotic snRNP
LLCC_RS08390	COG1393	Belongs to the ArsC family
LLCC_RS08395	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LLCC_RS08400	COG0420	3'-5' exonuclease activity
LLCC_RS08405	COG0419	ATPase involved in DNA repair
LLCC_RS08430	COG0803	Belongs to the bacterial solute-binding protein 9 family
LLCC_RS08455	COG0395	ABC-type sugar transport system, permease component
LLCC_RS08460	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
LLCC_RS08485	COG1349	DNA-binding transcription factor activity
LLCC_RS08540	COG0668	transmembrane transport
LLCC_RS08545	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LLCC_RS08550	COG0110	maltose O-acetyltransferase activity
LLCC_RS08555	COG0067	glutamate synthase
LLCC_RS08555	COG0069	glutamate synthase activity
LLCC_RS08555	COG0070	glutamate synthase
LLCC_RS08560	COG0493	'glutamate synthase
LLCC_RS08570	COG3763	UPF0154 protein
LLCC_RS08580	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LLCC_RS08595	COG4974	Belongs to the 'phage' integrase family
LLCC_RS08605	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LLCC_RS08610	COG1187	pseudouridine synthase activity
LLCC_RS08640	COG1132	(ABC) transporter
LLCC_RS08645	COG1132	(ABC) transporter
LLCC_RS08650	COG3620	sequence-specific DNA binding
LLCC_RS08665	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LLCC_RS08670	COG0222	ribosome binding
LLCC_RS08710	COG0351	phosphomethylpyrimidine kinase
LLCC_RS08725	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LLCC_RS08730	COG1696	Membrane protein involved in D-alanine export
LLCC_RS08735	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LLCC_RS08740	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
LLCC_RS08745	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LLCC_RS08795	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LLCC_RS08815	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LLCC_RS08820	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
LLCC_RS08825	COG2226	methyltransferase
LLCC_RS08830	COG0628	permease
LLCC_RS08840	COG0028	Belongs to the TPP enzyme family
LLCC_RS08845	COG2814	Major facilitator Superfamily
LLCC_RS08850	COG1733	regulation of RNA biosynthetic process
LLCC_RS08865	COG0557	exoribonuclease II activity
LLCC_RS08895	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LLCC_RS08905	COG3231	kanamycin kinase activity
LLCC_RS08910	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LLCC_RS08925	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LLCC_RS08925	COG0140	phosphoribosyl-ATP diphosphatase activity
LLCC_RS08930	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LLCC_RS08935	COG1054	Belongs to the UPF0176 family
LLCC_RS08955	COG0473	3-isopropylmalate dehydrogenase activity
LLCC_RS08980	COG0066	3-isopropylmalate dehydratase activity
LLCC_RS08985	COG1119	ATPase activity
LLCC_RS08995	COG0028	Belongs to the TPP enzyme family
LLCC_RS09000	COG0440	acetolactate synthase activity
LLCC_RS09005	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LLCC_RS09010	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LLCC_RS09015	COG3527	Alpha-acetolactate decarboxylase
LLCC_RS09020	COG0251	oxidation-reduction process
LLCC_RS09025	COG0758	DNA mediated transformation
LLCC_RS09030	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LLCC_RS09080	COG2207	Transcriptional regulator
LLCC_RS09080	COG1917	Cupin 2, conserved barrel domain protein
LLCC_RS09090	COG1177	transmembrane transport
LLCC_RS09095	COG1176	ABC-type spermidine putrescine transport system, permease component I
LLCC_RS09130	COG0285	dihydrofolate synthase activity
LLCC_RS09140	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LLCC_RS09145	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LLCC_RS09145	COG0302	gtp cyclohydrolase
LLCC_RS09170	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LLCC_RS09175	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LLCC_RS09185	COG2233	PERMEase
LLCC_RS09230	COG0647	UMP catabolic process
LLCC_RS09250	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LLCC_RS09280	COG1737	Transcriptional regulator
LLCC_RS09285	COG1263	PTS System
LLCC_RS09285	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LLCC_RS09290	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LLCC_RS09300	COG0039	L-malate dehydrogenase activity
LLCC_RS09305	COG0196	riboflavin kinase activity
LLCC_RS09360	COG1053	succinate dehydrogenase
LLCC_RS09370	COG0519	Catalyzes the synthesis of GMP from XMP
LLCC_RS09380	COG0210	DNA helicase
LLCC_RS09400	COG3764	Sortase (surface protein transpeptidase)
LLCC_RS09440	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
LLCC_RS09450	COG0531	amino acid
LLCC_RS09455	COG0702	epimerase
LLCC_RS09465	COG3527	Alpha-acetolactate decarboxylase
LLCC_RS09470	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LLCC_RS09475	COG3442	glutamine amidotransferase
LLCC_RS09485	COG1136	(ABC) transporter
LLCC_RS09500	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LLCC_RS09510	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LLCC_RS09515	COG0038	chloride channel
LLCC_RS09540	COG0737	Belongs to the 5'-nucleotidase family
LLCC_RS09555	COG1739	Uncharacterized protein family UPF0029
LLCC_RS09575	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LLCC_RS09580	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LLCC_RS09590	COG1702	phosphate starvation-inducible protein PhoH
LLCC_RS09605	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LLCC_RS09615	COG0261	This protein binds to 23S rRNA in the presence of protein L20
LLCC_RS09630	COG1078	dGTPase activity
LLCC_RS09645	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LLCC_RS09650	COG2384	SAM-dependent methyltransferase
LLCC_RS09655	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LLCC_RS09690	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LLCC_RS09700	COG0488	(ABC) transporter
LLCC_RS09705	COG1393	Belongs to the ArsC family
LLCC_RS09730	COG3942	CHAP domain
LLCC_RS09730	COG1388	LysM domain
LLCC_RS09855	COG0756	dUTP diphosphatase activity
LLCC_RS09895	COG2189	Belongs to the N(4) N(6)-methyltransferase family
LLCC_RS09965	COG2003	Belongs to the UPF0758 family
LLCC_RS09970	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LLCC_RS09975	COG0671	phosphoesterase, PA-phosphatase related
LLCC_RS09980	COG5002	protein histidine kinase activity
LLCC_RS09990	COG0745	RESPONSE REGULATOR receiver
LLCC_RS09995	COG0463	Glycosyl transferase, family 2
LLCC_RS10005	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
LLCC_RS10010	COG0564	pseudouridine synthase activity
LLCC_RS10040	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LLCC_RS10040	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LLCC_RS10065	COG2153	protein acetylation
LLCC_RS10070	COG2176	DNA-directed DNA polymerase activity
LLCC_RS10080	COG0187	DNA topoisomerase II activity
LLCC_RS10090	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LLCC_RS10100	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LLCC_RS10105	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LLCC_RS10110	COG2177	Part of the ABC transporter FtsEX involved in
LLCC_RS10115	COG2884	Cell division ATP-binding protein ftsE
LLCC_RS10135	COG2116	formate transmembrane transporter activity
LLCC_RS10155	COG1481	regulation of sporulation
LLCC_RS10160	COG0391	Required for morphogenesis under gluconeogenic growth conditions
LLCC_RS10170	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LLCC_RS10175	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LLCC_RS10225	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LLCC_RS10225	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LLCC_RS10225	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LLCC_RS10230	COG1105	Belongs to the carbohydrate kinase PfkB family
LLCC_RS10235	COG1349	DNA-binding transcription factor activity
LLCC_RS10240	COG1473	amidohydrolase
LLCC_RS10250	COG5617	Psort location CytoplasmicMembrane, score
LLCC_RS10260	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LLCC_RS10280	COG0588	phosphoglycerate mutase activity
LLCC_RS10295	COG3830	Belongs to the UPF0237 family
LLCC_RS10315	COG0557	exoribonuclease II activity
LLCC_RS10325	COG0492	ferredoxin-NADP+ reductase activity
LLCC_RS10335	COG1126	abc transporter atp-binding protein
LLCC_RS10340	COG0765	amino acid transport
LLCC_RS10345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LLCC_RS10360	COG0393	Putative heavy-metal-binding
LLCC_RS10375	COG0813	purine-nucleoside phosphorylase activity
LLCC_RS10390	COG1316	TRANSCRIPTIONal
LLCC_RS10485	COG0187	DNA topoisomerase II activity
LLCC_RS10495	COG2514	catechol 2,3-dioxygenase activity
LLCC_RS10530	COG0488	(ABC) transporter
LLCC_RS10545	COG0772	Belongs to the SEDS family
LLCC_RS10555	COG0539	negative regulation of cytoplasmic translation
LLCC_RS10565	COG2197	response regulator
LLCC_RS10570	COG4585	Histidine kinase
LLCC_RS10635	COG3328	transposase activity
LLCC_RS10645	COG3328	transposase activity
LLCC_RS10670	COG4974	Belongs to the 'phage' integrase family
LLCC_RS10675	COG2151	metal-sulfur cluster biosynthetic enzyme
LLCC_RS10705	COG0589	response to stress
LLCC_RS10725	COG1215	transferase activity, transferring glycosyl groups
LLCC_RS10740	COG4319	ketosteroid isomerase
LLCC_RS10745	COG0335	large ribosomal subunit rRNA binding
LLCC_RS10750	COG2357	RelA SpoT domain protein
LLCC_RS10765	COG0583	DNA-binding transcription factor activity
LLCC_RS10770	COG1136	(ABC) transporter
LLCC_RS10775	COG0577	efflux transmembrane transporter activity
LLCC_RS10785	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LLCC_RS10790	COG0768	penicillin binding
LLCC_RS10800	COG0275	rRNA processing
LLCC_RS10825	COG0497	DNA recombination
LLCC_RS10830	COG1438	arginine binding
LLCC_RS10835	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
LLCC_RS10850	COG1929	Belongs to the glycerate kinase type-1 family
LLCC_RS10865	COG1570	exodeoxyribonuclease VII activity
LLCC_RS10870	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LLCC_RS10875	COG2217	Heavy metal translocating P-type atpase
LLCC_RS10905	COG1174	glycine betaine transport
LLCC_RS10915	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LLCC_RS10930	COG0736	holo-[acyl-carrier-protein] synthase activity
LLCC_RS10980	COG3328	transposase activity
LLCC_RS10985	COG1194	a g-specific adenine glycosylase
LLCC_RS10990	COG0322	excinuclease ABC activity
LLCC_RS10995	COG3201	nicotinamide mononucleotide transporter
LLCC_RS11005	COG5002	protein histidine kinase activity
LLCC_RS11020	COG0539	negative regulation of cytoplasmic translation
LLCC_RS11040	COG2217	Heavy metal translocating P-type atpase
LLCC_RS11045	COG2608	mercury ion transmembrane transporter activity
LLCC_RS11050	COG3682	Transcriptional regulator
LLCC_RS11055	COG1760	l-serine dehydratase
LLCC_RS11060	COG1760	l-serine dehydratase
LLCC_RS11065	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LLCC_RS11095	COG2723	6-phospho-beta-galactosidase activity
LLCC_RS11100	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LLCC_RS11120	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LLCC_RS11125	COG0552	protein localization to endoplasmic reticulum
LLCC_RS11135	COG0561	phosphatase activity
LLCC_RS11140	COG1113	amino acid transport
LLCC_RS11160	COG1368	sulfuric ester hydrolase activity
LLCC_RS11165	COG1196	nuclear chromosome segregation
LLCC_RS11185	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LLCC_RS11200	COG2910	NAD(P)H-binding
LLCC_RS11205	COG4708	membrane
LLCC_RS11215	COG1028	Short-chain dehydrogenase reductase Sdr
LLCC_RS11225	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LLCC_RS11225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LLCC_RS11230	COG0708	Exodeoxyribonuclease III
LLCC_RS11250	COG1349	DNA-binding transcription factor activity
LLCC_RS11255	COG1393	Belongs to the ArsC family
LLCC_RS11260	COG1937	Protein conserved in bacteria
LLCC_RS11265	COG0446	pyridine nucleotide-disulphide oxidoreductase
LLCC_RS11270	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LLCC_RS11275	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LLCC_RS11305	COG0439	Biotin carboxylase
LLCC_RS11320	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LLCC_RS11325	COG1028	Short-chain dehydrogenase reductase Sdr
LLCC_RS11330	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LLCC_RS11335	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LLCC_RS11350	COG3328	transposase activity
LLCC_RS11355	COG1482	cell wall glycoprotein biosynthetic process
LLCC_RS11360	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LLCC_RS11380	COG0195	Participates in both transcription termination and antitermination
LLCC_RS11395	COG1346	cytolysis
LLCC_RS11440	COG1160	GTP binding
LLCC_RS11450	COG0778	Nitroreductase
LLCC_RS11455	COG1484	DNA-dependent DNA replication
LLCC_RS11465	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LLCC_RS11485	COG0305	Participates in initiation and elongation during chromosome replication
LLCC_RS11500	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LLCC_RS11515	COG0527	aspartate kinase activity
LLCC_RS11520	COG2268	Band 7 protein
LLCC_RS11530	COG0561	phosphatase activity
LLCC_RS11535	COG0252	asparaginase activity
LLCC_RS11545	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LLCC_RS11550	COG4109	DRTGG domain
LLCC_RS11560	COG1169	isochorismate synthase
LLCC_RS11570	COG2267	carboxylic ester hydrolase activity
LLCC_RS11575	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LLCC_RS11580	COG0318	PFAM AMP-dependent synthetase and ligase
LLCC_RS11585	COG4948	Mandelate Racemase Muconate Lactonizing
LLCC_RS11595	COG1609	Transcriptional regulator
LLCC_RS11635	COG4209	transmembrane transport
LLCC_RS11660	COG1234	tRNA 3'-trailer cleavage
LLCC_RS11710	COG0586	Pfam SNARE associated Golgi protein
LLCC_RS11735	COG1846	Transcriptional regulator
LLCC_RS11740	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LLCC_RS11745	COG4988	ABC transporter
LLCC_RS11750	COG1294	oxidase, subunit
LLCC_RS11755	COG1271	oxidase subunit
LLCC_RS11760	COG3104	oligopeptide transport
LLCC_RS11790	COG1640	4-alpha-glucanotransferase
LLCC_RS11795	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LLCC_RS11805	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LLCC_RS11810	COG0006	proline dipeptidase activity
LLCC_RS11815	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LLCC_RS11820	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LLCC_RS11830	COG0084	hydrolase, TatD family'
LLCC_RS11835	COG3592	Divergent 4Fe-4S mono-cluster
LLCC_RS11845	COG1114	Component of the transport system for branched-chain amino acids
LLCC_RS11880	COG1393	Belongs to the ArsC family
LLCC_RS11890	COG0740	serine-type endopeptidase activity
LLCC_RS11910	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LLCC_RS11915	COG0772	Belongs to the SEDS family
LLCC_RS11920	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LLCC_RS11925	COG2814	Major facilitator Superfamily
LLCC_RS11930	COG0237	dephospho-CoA kinase activity
LLCC_RS11935	COG1882	Formate acetyltransferase
LLCC_RS11945	COG0318	PFAM AMP-dependent synthetase and ligase
LLCC_RS11955	COG0577	efflux transmembrane transporter activity
LLCC_RS11965	COG0148	phosphopyruvate hydratase activity
LLCC_RS11970	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LLCC_RS11975	COG0542	response to heat
LLCC_RS11995	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LLCC_RS12000	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LLCC_RS12010	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LLCC_RS12015	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LLCC_RS12015	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
LLCC_RS12020	COG0300	oxidoreductase activity
LLCC_RS12035	COG3328	transposase activity
LLCC_RS12090	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LLCC_RS12095	COG4980	gas vesicle protein
LLCC_RS12105	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LLCC_RS12110	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
LLCC_RS12130	COG2246	polysaccharide biosynthetic process
LLCC_RS12140	COG0024	Methionine aminopeptidase
LLCC_RS12165	COG0716	FMN binding
LLCC_RS12175	COG0789	Transcriptional regulator
LLCC_RS12190	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LLCC_RS12195	COG1254	Belongs to the acylphosphatase family
LLCC_RS12200	COG0560	Phosphoserine phosphatase
LLCC_RS12205	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LLCC_RS12215	COG0741	lytic transglycosylase activity
LLCC_RS12225	COG0009	L-threonylcarbamoyladenylate synthase
LLCC_RS12235	COG2890	protein-(glutamine-N5) methyltransferase activity
LLCC_RS12240	COG0778	Nitroreductase
LLCC_RS12260	COG1435	thymidine kinase activity
LLCC_RS12295	COG0456	acetyltransferase
LLCC_RS12305	COG1942	4-Oxalocrotonate Tautomerase
LLCC_RS12315	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LLCC_RS12320	COG4684	Psort location CytoplasmicMembrane, score
LLCC_RS12330	COG0706	membrane insertase activity
LLCC_RS12335	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
LLCC_RS12340	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LLCC_RS12350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LLCC_RS12360	COG0494	nUDIX hydrolase
LLCC_RS12365	COG0242	peptide deformylase activity
LLCC_RS12370	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LLCC_RS12375	COG1959	2 iron, 2 sulfur cluster binding
LLCC_RS12380	COG0542	response to heat
LLCC_RS12475	COG1335	isochorismatase
LLCC_RS12480	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LLCC_RS12560	COG0454	-acetyltransferase
LLCC_RS12595	COG1192	Involved in chromosome partitioning
LLCC_RS12610	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LLCC_RS12675	COG1266	CAAX protease self-immunity
LLCC_RS12760	COG3942	CHAP domain
LLCC_RS12760	COG1705	Flagellar rod assembly protein muramidase FlgJ
LLCC_RS12825	COG3843	relaxase mobilization nuclease domain protein
LLCC_RS12865	COG1192	Involved in chromosome partitioning
LLCC_RS12880	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LLCC_RS12920	COG1278	Cold shock
LLCC_RS13185	COG3942	CHAP domain
LLCC_RS13185	COG1705	Flagellar rod assembly protein muramidase FlgJ
LLCC_RS13225	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LLCC_RS13310	COG2746	aminoglycoside 3-N-acetyltransferase activity
LLCC_RS13335	COG1914	H( )-stimulated, divalent metal cation uptake system
LLCC_RS13420	COG4608	Belongs to the ABC transporter superfamily
LLCC_RS13425	COG0601	transmembrane transport
LLCC_RS13445	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LLCC_RS13485	COG3979	chitinase
LLCC_RS13500	COG1473	amidohydrolase
LLCC_RS13540	COG3843	relaxase mobilization nuclease domain protein
LLCC_RS13565	COG2223	nitrite transmembrane transporter activity
LLCC_RS13580	COG1266	CAAX protease self-immunity
LLCC_RS13630	COG0277	FAD linked oxidase domain protein
LLCC_RS13720	COG0601	transmembrane transport