locus-tag	class	description
JWR96_RS00010	COG2706	6-phosphogluconolactonase activity
JWR96_RS00015	COG0052	Belongs to the universal ribosomal protein uS2 family
JWR96_RS00020	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JWR96_RS00025	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
JWR96_RS00055	COG1609	Transcriptional regulator
JWR96_RS00065	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JWR96_RS00065	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JWR96_RS00070	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
JWR96_RS00085	COG0438	transferase activity, transferring glycosyl groups
JWR96_RS00095	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JWR96_RS00110	COG1862	Preprotein translocase
JWR96_RS00115	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JWR96_RS00120	COG4589	Belongs to the CDS family
JWR96_RS00125	COG0750	zinc metalloprotease
JWR96_RS00130	COG0442	prolyl-tRNA aminoacylation
JWR96_RS00145	COG2176	DNA-directed DNA polymerase activity
JWR96_RS00150	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JWR96_RS00155	COG1459	type II secretion system
JWR96_RS00160	COG4537	Required for transformation and DNA binding
JWR96_RS00185	COG1846	Transcriptional regulator
JWR96_RS00190	COG0803	Belongs to the bacterial solute-binding protein 9 family
JWR96_RS00190	COG3443	Belongs to the bacterial solute-binding protein 9 family
JWR96_RS00200	COG1121	(ABC) transporter
JWR96_RS00205	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JWR96_RS00210	COG0564	pseudouridine synthase activity
JWR96_RS00225	COG2323	membrane
JWR96_RS00230	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JWR96_RS00235	COG2755	lipolytic protein G-D-S-L family
JWR96_RS00235	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
JWR96_RS00240	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JWR96_RS00250	COG0250	Participates in transcription elongation, termination and antitermination
JWR96_RS00255	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
JWR96_RS00265	COG1970	mechanosensitive ion channel activity
JWR96_RS00270	COG0051	transcription antitermination factor activity, RNA binding
JWR96_RS00275	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JWR96_RS00290	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JWR96_RS00295	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JWR96_RS00300	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
JWR96_RS00305	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JWR96_RS00310	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
JWR96_RS00315	COG0255	Belongs to the universal ribosomal protein uL29 family
JWR96_RS00320	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JWR96_RS00325	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JWR96_RS00330	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
JWR96_RS00335	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
JWR96_RS00340	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JWR96_RS00350	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JWR96_RS00355	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JWR96_RS00360	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
JWR96_RS00365	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JWR96_RS00370	COG1841	ribosomal large subunit assembly
JWR96_RS00375	COG0200	Binds to the 23S rRNA
JWR96_RS00385	COG0563	adenylate kinase activity
JWR96_RS00390	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
JWR96_RS00395	COG0257	Belongs to the bacterial ribosomal protein bL36 family
JWR96_RS00400	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JWR96_RS00405	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JWR96_RS00410	COG0202	RNA polymerase activity
JWR96_RS00415	COG0203	ribosomal protein L17
JWR96_RS00430	COG1216	Glycosyl transferase, family 2
JWR96_RS00435	COG1216	Glycosyl transferase, family 2
JWR96_RS00455	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
JWR96_RS00460	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
JWR96_RS00465	COG1442	glycosyl transferase family 8
JWR96_RS00465	COG1216	Glycosyl transferase, family 2
JWR96_RS00480	COG4956	integral membrane protein (PIN domain superfamily)
JWR96_RS00520	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JWR96_RS00525	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JWR96_RS00530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JWR96_RS00535	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
JWR96_RS00550	COG1266	CAAX protease self-immunity
JWR96_RS00575	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JWR96_RS00580	COG0028	Belongs to the TPP enzyme family
JWR96_RS00590	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JWR96_RS00600	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JWR96_RS00615	COG2235	arginine
JWR96_RS00620	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JWR96_RS00625	COG0531	amino acid
JWR96_RS00645	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JWR96_RS00650	COG0531	amino acid
JWR96_RS00670	COG0783	Belongs to the Dps family
JWR96_RS00680	COG1940	carbohydrate kinase activity
JWR96_RS00715	COG1217	gtp-binding protein TYPA
JWR96_RS00725	COG0827	DNA restriction-modification system
JWR96_RS00730	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JWR96_RS00735	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JWR96_RS00760	COG2996	Protein conserved in bacteria
JWR96_RS00765	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JWR96_RS00770	COG4479	Belongs to the UPF0346 family
JWR96_RS00775	COG1131	(ABC) transporter
JWR96_RS00785	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
JWR96_RS00790	COG0081	regulation of translation
JWR96_RS00805	COG0537	adenosine 5'-monophosphoramidase activity
JWR96_RS00810	COG0584	glycerophosphoryl diester phosphodiesterase
JWR96_RS00815	COG1131	(ABC) transporter
JWR96_RS00830	COG0500	methyltransferase
JWR96_RS00845	COG0826	peptidase U32
JWR96_RS00860	COG0667	Aldo Keto reductase
JWR96_RS00880	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JWR96_RS00890	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JWR96_RS00905	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JWR96_RS00910	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JWR96_RS00915	COG2501	S4 domain
JWR96_RS00920	COG0612	Peptidase, M16
JWR96_RS00925	COG0612	Peptidase, M16
JWR96_RS00930	COG1426	Protein conserved in bacteria
JWR96_RS00935	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JWR96_RS00960	COG0124	histidyl-tRNA synthetase
JWR96_RS00965	COG0537	adenosine 5'-monophosphoramidase activity
JWR96_RS00970	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
JWR96_RS00975	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JWR96_RS00980	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JWR96_RS00985	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JWR96_RS00995	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JWR96_RS01015	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JWR96_RS01035	COG3397	chitin binding
JWR96_RS01050	COG3479	Phenolic acid decarboxylase
JWR96_RS01055	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JWR96_RS01060	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JWR96_RS01060	COG0072	phenylalanine-tRNA ligase activity
JWR96_RS01065	COG1388	LysM domain
JWR96_RS01065	COG3584	3D domain protein
JWR96_RS01070	COG1162	GTPase activity
JWR96_RS01095	COG3481	metal-dependent phosphohydrolase, HD sub domain
JWR96_RS01115	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
JWR96_RS01120	COG0626	cystathionine gamma-synthase activity
JWR96_RS01135	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JWR96_RS01160	COG2860	membrane
JWR96_RS01220	COG0191	fructose-bisphosphate aldolase activity
JWR96_RS01225	COG3942	CHAP domain
JWR96_RS01225	COG1705	Flagellar rod assembly protein muramidase FlgJ
JWR96_RS01245	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
JWR96_RS01245	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
JWR96_RS01250	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JWR96_RS01255	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JWR96_RS01260	COG0363	glucosamine-6-phosphate deaminase activity
JWR96_RS01270	COG0194	GDP metabolic process
JWR96_RS01275	COG1758	RNA polymerase activity
JWR96_RS01280	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JWR96_RS01310	COG2261	transglycosylase associated protein
JWR96_RS01330	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JWR96_RS01330	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JWR96_RS01335	COG0631	protein serine/threonine phosphatase activity
JWR96_RS01340	COG2815	serine threonine protein kinase
JWR96_RS01340	COG0515	serine threonine protein kinase
JWR96_RS01345	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
JWR96_RS01350	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JWR96_RS01360	COG0494	nUDIX hydrolase
JWR96_RS01370	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JWR96_RS01395	COG0583	DNA-binding transcription factor activity
JWR96_RS01405	COG0656	L-ascorbic acid biosynthetic process
JWR96_RS01410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JWR96_RS01420	COG1307	EDD domain protein, DegV family
JWR96_RS01425	COG0849	cell division
JWR96_RS01430	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JWR96_RS01435	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
JWR96_RS01440	COG1799	cell septum assembly
JWR96_RS01450	COG2302	S4 RNA-binding domain
JWR96_RS01455	COG3599	regulation of cell shape
JWR96_RS01460	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JWR96_RS01475	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JWR96_RS01485	COG1104	cysteine desulfurase activity
JWR96_RS01490	COG0589	response to stress
JWR96_RS01495	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JWR96_RS01515	COG1045	serine acetyltransferase
JWR96_RS01525	COG0215	cysteine-tRNA ligase activity
JWR96_RS01530	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
JWR96_RS01560	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
JWR96_RS01565	COG0291	Belongs to the bacterial ribosomal protein bL35 family
JWR96_RS01570	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
JWR96_RS01575	COG0444	Belongs to the ABC transporter superfamily
JWR96_RS01580	COG4608	Belongs to the ABC transporter superfamily
JWR96_RS01585	COG0601	transmembrane transport
JWR96_RS01605	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JWR96_RS01605	COG1199	ATP-dependent helicase activity
JWR96_RS01615	COG0436	Aminotransferase
JWR96_RS01625	COG0017	Asparaginyl-tRNA synthetase
JWR96_RS01645	COG1564	THIamine pyrophosphokinase
JWR96_RS01655	COG1113	amino acid transport
JWR96_RS01660	COG2827	Endonuclease containing a URI domain
JWR96_RS01670	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JWR96_RS01675	COG1573	uracil-dna glycosylase
JWR96_RS01695	COG0628	permease
JWR96_RS01700	COG1253	flavin adenine dinucleotide binding
JWR96_RS01705	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JWR96_RS01710	COG1227	inorganic diphosphatase activity
JWR96_RS01720	COG2195	Cleaves the N-terminal amino acid of tripeptides
JWR96_RS01730	COG0514	ATP-dependent DNA helicase (RecQ)
JWR96_RS01735	COG1064	alcohol dehydrogenase
JWR96_RS01745	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JWR96_RS01750	COG2244	polysaccharide biosynthetic process
JWR96_RS01760	COG3590	peptidase
JWR96_RS01765	COG1396	sequence-specific DNA binding
JWR96_RS01775	COG0085	RNA polymerase activity
JWR96_RS01780	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JWR96_RS01785	COG0085	RNA polymerase activity
JWR96_RS01790	COG0765	amino acid transport
JWR96_RS01795	COG1126	abc transporter atp-binding protein
JWR96_RS01800	COG4862	establishment of competence for transformation
JWR96_RS01805	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JWR96_RS01815	COG0719	Fe-S assembly protein
JWR96_RS01820	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JWR96_RS01835	COG0719	Fe-S assembly protein
JWR96_RS01840	COG4842	Belongs to the WXG100 family
JWR96_RS01855	COG4499	WXG100 protein secretion system (Wss), protein YukC
JWR96_RS01860	COG1674	ftsk spoiiie
JWR96_RS01940	COG0183	Belongs to the thiolase family
JWR96_RS01945	COG0318	PFAM AMP-dependent synthetase and ligase
JWR96_RS01950	COG1268	BioY protein
JWR96_RS01965	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
JWR96_RS01985	COG4152	abc transporter atp-binding protein
JWR96_RS01995	COG1596	polysaccharide export
JWR96_RS01995	COG1555	photosystem II stabilization
JWR96_RS02000	COG0658	competence protein
JWR96_RS02000	COG2333	competence protein COMEC
JWR96_RS02015	COG0356	it plays a direct role in the translocation of protons across the membrane
JWR96_RS02020	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JWR96_RS02030	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JWR96_RS02040	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JWR96_RS02060	COG1126	abc transporter atp-binding protein
JWR96_RS02065	COG0765	amino acid transport
JWR96_RS02075	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JWR96_RS02080	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JWR96_RS02090	COG4493	Belongs to the UPF0637 family
JWR96_RS02100	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
JWR96_RS02110	COG1136	(ABC) transporter
JWR96_RS02115	COG0577	efflux transmembrane transporter activity
JWR96_RS02125	COG0745	RESPONSE REGULATOR receiver
JWR96_RS02130	COG5002	protein histidine kinase activity
JWR96_RS02135	COG0287	Prephenate dehydrogenase
JWR96_RS02150	COG0077	Prephenate dehydratase
JWR96_RS02160	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
JWR96_RS02165	COG0268	Binds directly to 16S ribosomal RNA
JWR96_RS02180	COG0670	Belongs to the BI1 family
JWR96_RS02185	COG1556	Lactate utilization protein
JWR96_RS02190	COG1139	Iron-sulfur cluster binding protein
JWR96_RS02195	COG0247	lactate metabolic process
JWR96_RS02200	COG0561	phosphatase activity
JWR96_RS02205	COG2252	PERMEase
JWR96_RS02230	COG4122	O-methyltransferase activity
JWR96_RS02235	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JWR96_RS02260	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
JWR96_RS02275	COG0573	inorganic phosphate transmembrane transporter activity
JWR96_RS02280	COG0581	inorganic phosphate transmembrane transporter activity
JWR96_RS02285	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JWR96_RS02290	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JWR96_RS02295	COG0704	Plays a role in the regulation of phosphate uptake
JWR96_RS02305	COG1619	proteins homologs of microcin C7 resistance protein MccF
JWR96_RS02325	COG1131	(ABC) transporter
JWR96_RS02335	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JWR96_RS02355	COG3716	PTS system mannose fructose sorbose family IID component
JWR96_RS02360	COG3715	PTS system
JWR96_RS02380	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
JWR96_RS02395	COG2197	response regulator
JWR96_RS02400	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JWR96_RS02405	COG0531	amino acid
JWR96_RS02410	COG2957	Belongs to the agmatine deiminase family
JWR96_RS02420	COG1902	pentaerythritol trinitrate reductase activity
JWR96_RS02425	COG0640	Transcriptional regulator
JWR96_RS02485	COG3833	ABC-type maltose transport systems, permease component
JWR96_RS02490	COG1175	transmembrane transport
JWR96_RS02500	COG0366	Alpha amylase catalytic
JWR96_RS02510	COG0366	Alpha amylase catalytic
JWR96_RS02515	COG0110	maltose O-acetyltransferase activity
JWR96_RS02520	COG0366	Alpha amylase catalytic
JWR96_RS02525	COG0366	Alpha amylase catalytic
JWR96_RS02535	COG1609	Transcriptional regulator
JWR96_RS02540	COG0745	RESPONSE REGULATOR receiver
JWR96_RS02545	COG5002	protein histidine kinase activity
JWR96_RS02550	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
JWR96_RS02560	COG2723	6-phospho-beta-galactosidase activity
JWR96_RS02610	COG0741	lytic transglycosylase activity
JWR96_RS02620	COG0673	inositol 2-dehydrogenase activity
JWR96_RS02625	COG0572	uridine kinase
JWR96_RS02630	COG0280	phosphate acetyltransferase
JWR96_RS02640	COG0561	phosphatase activity
JWR96_RS02645	COG1674	ftsk spoiiie
JWR96_RS02655	COG1466	dna polymerase III delta subunit
JWR96_RS02660	COG3599	regulation of cell shape
JWR96_RS02670	COG0116	Belongs to the methyltransferase superfamily
JWR96_RS02680	COG0006	proline dipeptidase activity
JWR96_RS02685	COG1609	Transcriptional regulator
JWR96_RS02690	COG0492	ferredoxin-NADP+ reductase activity
JWR96_RS02695	COG1286	toxin biosynthetic process
JWR96_RS02700	COG1193	negative regulation of DNA recombination
JWR96_RS02705	COG3118	belongs to the thioredoxin family
JWR96_RS02720	COG0710	3-dehydroquinate dehydratase activity
JWR96_RS02725	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JWR96_RS02730	COG1609	Transcriptional regulator
JWR96_RS02735	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JWR96_RS02740	COG1869	D-ribose catabolic process
JWR96_RS02750	COG1172	Belongs to the binding-protein-dependent transport system permease family
JWR96_RS02755	COG1879	ABC-type sugar transport system periplasmic component
JWR96_RS02760	COG0582	viral genome integration into host DNA
JWR96_RS02795	COG3561	AntA/AntB antirepressor
JWR96_RS02840	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JWR96_RS02890	COG0756	dUTP diphosphatase activity
JWR96_RS02940	COG5484	DNA packaging
JWR96_RS02940	COG3728	DNA packaging
JWR96_RS02965	COG2868	ribosomal protein
JWR96_RS03095	COG0477	Major facilitator Superfamily
JWR96_RS03100	COG1802	Transcriptional regulator
JWR96_RS03105	COG0246	Mannitol dehydrogenase
JWR96_RS03110	COG1312	Catalyzes the dehydration of D-mannonate
JWR96_RS03125	COG1904	glucuronate isomerase
JWR96_RS03130	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JWR96_RS03135	COG0800	Aldolase
JWR96_RS03140	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JWR96_RS03170	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JWR96_RS03185	COG1285	pathogenesis
JWR96_RS03200	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JWR96_RS03240	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JWR96_RS03245	COG1230	cation diffusion facilitator family transporter
JWR96_RS03280	COG0505	Belongs to the CarA family
JWR96_RS03310	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JWR96_RS03315	COG1408	metallophosphoesterase
JWR96_RS03320	COG1705	Flagellar rod assembly protein muramidase FlgJ
JWR96_RS03320	COG3942	CHAP domain
JWR96_RS03330	COG0254	rRNA binding
JWR96_RS03340	COG0745	RESPONSE REGULATOR receiver
JWR96_RS03345	COG5002	protein histidine kinase activity
JWR96_RS03350	COG0004	ammonium transporteR
JWR96_RS03355	COG0347	Belongs to the P(II) protein family
JWR96_RS03360	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JWR96_RS03365	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JWR96_RS03375	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JWR96_RS03390	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
JWR96_RS03400	COG0363	glucosamine-6-phosphate deaminase activity
JWR96_RS03405	COG3425	synthase
JWR96_RS03410	COG0183	Belongs to the thiolase family
JWR96_RS03420	COG0228	four-way junction DNA binding
JWR96_RS03425	COG1837	Belongs to the UPF0109 family
JWR96_RS03445	COG0336	Belongs to the RNA methyltransferase TrmD family
JWR96_RS03455	COG1307	EDD domain protein, DegV family
JWR96_RS03460	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JWR96_RS03470	COG0617	tRNA 3'-terminal CCA addition
JWR96_RS03475	COG4690	dipeptidase activity
JWR96_RS03485	COG0371	Dehydrogenase
JWR96_RS03495	COG0488	(ABC) transporter
JWR96_RS03505	COG0673	inositol 2-dehydrogenase activity
JWR96_RS03510	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JWR96_RS03515	COG0167	dihydroorotate dehydrogenase activity
JWR96_RS03530	COG1063	alcohol dehydrogenase
JWR96_RS03545	COG1846	Transcriptional regulator
JWR96_RS03550	COG0477	Major facilitator Superfamily
JWR96_RS03555	COG4221	oxidoreductase activity
JWR96_RS03565	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JWR96_RS03580	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
JWR96_RS03590	COG0047	phosphoribosylformylglycinamidine synthase activity
JWR96_RS03595	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JWR96_RS03625	COG0542	response to heat
JWR96_RS03635	COG3177	Filamentation induced by cAMP protein fic
JWR96_RS03650	COG0732	type I restriction modification DNA specificity domain
JWR96_RS03670	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
JWR96_RS03675	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JWR96_RS03700	COG0138	bifunctional purine biosynthesis protein purh
JWR96_RS03705	COG1011	Hydrolase
JWR96_RS03710	COG2814	Major facilitator Superfamily
JWR96_RS03730	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JWR96_RS03745	COG2115	Belongs to the xylose isomerase family
JWR96_RS03765	COG2211	Major facilitator Superfamily
JWR96_RS03770	COG3507	Belongs to the glycosyl hydrolase 43 family
JWR96_RS03775	COG0656	L-ascorbic acid biosynthetic process
JWR96_RS03790	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
JWR96_RS03810	COG0383	alpha-mannosidase activity
JWR96_RS03815	COG1175	transmembrane transport
JWR96_RS03820	COG0395	ABC-type sugar transport system, permease component
JWR96_RS03825	COG1653	transport
JWR96_RS03835	COG0366	Alpha amylase catalytic
JWR96_RS03850	COG2723	6-phospho-beta-galactosidase activity
JWR96_RS03865	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JWR96_RS03865	COG0519	Catalyzes the synthesis of GMP from XMP
JWR96_RS03870	COG4209	transmembrane transport
JWR96_RS03875	COG0395	ABC-type sugar transport system, permease component
JWR96_RS03910	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
JWR96_RS03915	COG0300	oxidoreductase activity
JWR96_RS03920	COG0789	Transcriptional regulator
JWR96_RS03925	COG0697	spore germination
JWR96_RS03930	COG0735	belongs to the Fur family
JWR96_RS03955	COG0778	Nitroreductase
JWR96_RS03960	COG3759	membrane
JWR96_RS03965	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JWR96_RS03970	COG0512	Glutamine amidotransferase of anthranilate synthase
JWR96_RS03975	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JWR96_RS03980	COG0134	indole-3-glycerol-phosphate synthase activity
JWR96_RS03985	COG0135	phosphoribosylanthranilate isomerase activity
JWR96_RS04005	COG3711	transcriptional antiterminator
JWR96_RS04010	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JWR96_RS04010	COG2190	(PTS) system
JWR96_RS04010	COG1263	PTS System
JWR96_RS04015	COG2723	6-phospho-beta-galactosidase activity
JWR96_RS04025	COG3448	diguanylate cyclase activity
JWR96_RS04025	COG4175	Glycine betaine
JWR96_RS04045	COG3969	phosphoadenosine phosphosulfate
JWR96_RS04050	COG1475	DNA binding
JWR96_RS04070	COG1072	(Pantothenic acid kinase))
JWR96_RS04075	COG2813	Specifically methylates the guanine in position
JWR96_RS04090	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JWR96_RS04100	COG1744	ABC transporter substrate-binding protein PnrA-like
JWR96_RS04105	COG2188	Transcriptional regulator
JWR96_RS04120	COG0745	RESPONSE REGULATOR receiver
JWR96_RS04125	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
JWR96_RS04165	COG0346	lactoylglutathione lyase activity
JWR96_RS04210	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JWR96_RS04215	COG1705	Flagellar rod assembly protein muramidase FlgJ
JWR96_RS04220	COG0386	Belongs to the glutathione peroxidase family
JWR96_RS04225	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JWR96_RS04265	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JWR96_RS04270	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
JWR96_RS04275	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JWR96_RS04280	COG1187	pseudouridine synthase activity
JWR96_RS04315	COG1175	transmembrane transport
JWR96_RS04335	COG2723	6-phospho-beta-galactosidase activity
JWR96_RS04345	COG2814	Major facilitator Superfamily
JWR96_RS04350	COG0543	2 iron, 2 sulfur cluster binding
JWR96_RS04355	COG0167	dihydroorotate dehydrogenase activity
JWR96_RS04370	COG0357	Ribosomal RNA small subunit methyltransferase G
JWR96_RS04395	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
JWR96_RS04405	COG3853	Toxic anion resistance protein (TelA)
JWR96_RS04415	COG0205	6-phosphofructokinase activity
JWR96_RS04420	COG0469	pyruvate kinase activity
JWR96_RS04425	COG0039	L-malate dehydrogenase activity
JWR96_RS04430	COG1079	Belongs to the binding-protein-dependent transport system permease family
JWR96_RS04435	COG4603	Belongs to the binding-protein-dependent transport system permease family
JWR96_RS04440	COG3845	ABC transporter
JWR96_RS04445	COG2226	methyltransferase
JWR96_RS04450	COG1293	RNA-binding protein homologous to eukaryotic snRNP
JWR96_RS04465	COG1393	Belongs to the ArsC family
JWR96_RS04470	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JWR96_RS04475	COG0420	3'-5' exonuclease activity
JWR96_RS04480	COG0419	ATPase involved in DNA repair
JWR96_RS04505	COG0803	Belongs to the bacterial solute-binding protein 9 family
JWR96_RS04520	COG1396	sequence-specific DNA binding
JWR96_RS04540	COG2423	ornithine cyclodeaminase activity
JWR96_RS04550	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JWR96_RS04570	COG1393	Belongs to the ArsC family
JWR96_RS04590	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JWR96_RS04590	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JWR96_RS04590	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JWR96_RS04600	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JWR96_RS04635	COG3961	Belongs to the TPP enzyme family
JWR96_RS04650	COG0346	lactoylglutathione lyase activity
JWR96_RS04655	COG0110	maltose O-acetyltransferase activity
JWR96_RS04660	COG0561	phosphatase activity
JWR96_RS04695	COG0395	ABC-type sugar transport system, permease component
JWR96_RS04725	COG1349	DNA-binding transcription factor activity
JWR96_RS04750	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JWR96_RS04760	COG0531	amino acid
JWR96_RS04765	COG0076	glutamate decarboxylase activity
JWR96_RS04770	COG0668	transmembrane transport
JWR96_RS04775	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JWR96_RS04780	COG0110	maltose O-acetyltransferase activity
JWR96_RS04785	COG0069	glutamate synthase activity
JWR96_RS04785	COG0070	glutamate synthase
JWR96_RS04785	COG0067	glutamate synthase
JWR96_RS04790	COG0493	'glutamate synthase
JWR96_RS04800	COG3763	UPF0154 protein
JWR96_RS04805	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
JWR96_RS04810	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JWR96_RS04825	COG4974	Belongs to the 'phage' integrase family
JWR96_RS04830	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
JWR96_RS04835	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JWR96_RS04840	COG1187	pseudouridine synthase activity
JWR96_RS04870	COG1132	(ABC) transporter
JWR96_RS04875	COG1132	(ABC) transporter
JWR96_RS04880	COG3620	sequence-specific DNA binding
JWR96_RS04895	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JWR96_RS04900	COG0222	ribosome binding
JWR96_RS04905	COG1846	Transcriptional regulator
JWR96_RS04910	COG2814	Major facilitator Superfamily
JWR96_RS04920	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
JWR96_RS04935	COG0351	phosphomethylpyrimidine kinase
JWR96_RS04940	COG0352	thiamine-phosphate diphosphorylase activity
JWR96_RS04950	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JWR96_RS04955	COG1696	Membrane protein involved in D-alanine export
JWR96_RS04960	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JWR96_RS04965	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
JWR96_RS04970	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JWR96_RS04990	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
JWR96_RS05010	COG0640	Transcriptional regulator
JWR96_RS05050	COG4974	Belongs to the 'phage' integrase family
JWR96_RS05055	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
JWR96_RS05060	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JWR96_RS05065	COG0758	DNA mediated transformation
JWR96_RS05070	COG0251	oxidation-reduction process
JWR96_RS05075	COG3527	Alpha-acetolactate decarboxylase
JWR96_RS05080	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JWR96_RS05085	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
JWR96_RS05090	COG0440	acetolactate synthase activity
JWR96_RS05095	COG0028	Belongs to the TPP enzyme family
JWR96_RS05105	COG1119	ATPase activity
JWR96_RS05110	COG0066	3-isopropylmalate dehydratase activity
JWR96_RS05120	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JWR96_RS05135	COG0473	3-isopropylmalate dehydrogenase activity
JWR96_RS05160	COG1054	Belongs to the UPF0176 family
JWR96_RS05165	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JWR96_RS05170	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
JWR96_RS05170	COG0140	phosphoribosyl-ATP diphosphatase activity
JWR96_RS05175	COG0107	imidazoleglycerol-phosphate synthase activity
JWR96_RS05185	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
JWR96_RS05190	COG3231	kanamycin kinase activity
JWR96_RS05205	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
JWR96_RS05210	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
JWR96_RS05225	COG1461	Dihydroxyacetone kinase
JWR96_RS05240	COG0557	exoribonuclease II activity
JWR96_RS05250	COG1396	sequence-specific DNA binding
JWR96_RS05295	COG0028	Belongs to the TPP enzyme family
JWR96_RS05305	COG0628	permease
JWR96_RS05315	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
JWR96_RS05320	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JWR96_RS05330	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
JWR96_RS05335	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JWR96_RS05345	COG0656	L-ascorbic acid biosynthetic process
JWR96_RS05355	COG1393	Belongs to the ArsC family
JWR96_RS05400	COG1131	(ABC) transporter
JWR96_RS05440	COG1940	carbohydrate kinase activity
JWR96_RS05450	COG1609	Transcriptional regulator
JWR96_RS05470	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JWR96_RS05545	COG1917	Cupin 2, conserved barrel domain protein
JWR96_RS05545	COG2207	Transcriptional regulator
JWR96_RS05555	COG1177	transmembrane transport
JWR96_RS05560	COG1176	ABC-type spermidine putrescine transport system, permease component I
JWR96_RS05570	COG0812	UDP-N-acetylmuramate dehydrogenase activity
JWR96_RS05580	COG0083	homoserine kinase activity
JWR96_RS05590	COG1428	Deoxynucleoside kinase
JWR96_RS05595	COG0285	dihydrofolate synthase activity
JWR96_RS05605	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JWR96_RS05635	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JWR96_RS05640	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
JWR96_RS05650	COG2233	PERMEase
JWR96_RS05655	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JWR96_RS05705	COG0647	UMP catabolic process
JWR96_RS05725	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JWR96_RS05730	COG1475	DNA binding
JWR96_RS05735	COG3969	phosphoadenosine phosphosulfate
JWR96_RS05755	COG1737	Transcriptional regulator
JWR96_RS05760	COG1263	PTS System
JWR96_RS05760	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JWR96_RS05765	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
JWR96_RS05775	COG0039	L-malate dehydrogenase activity
JWR96_RS05780	COG0196	riboflavin kinase activity
JWR96_RS05785	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JWR96_RS05840	COG0519	Catalyzes the synthesis of GMP from XMP
JWR96_RS05845	COG2816	NAD+ diphosphatase activity
JWR96_RS05850	COG0210	DNA helicase
JWR96_RS05865	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
JWR96_RS05865	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
JWR96_RS05870	COG3764	Sortase (surface protein transpeptidase)
JWR96_RS05885	COG0531	amino acid
JWR96_RS05890	COG0702	epimerase
JWR96_RS05895	COG1940	carbohydrate kinase activity
JWR96_RS05900	COG2723	6-phospho-beta-galactosidase activity
JWR96_RS05910	COG0444	Belongs to the ABC transporter superfamily
JWR96_RS05915	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JWR96_RS05920	COG0601	transmembrane transport
JWR96_RS05925	COG4608	Belongs to the ABC transporter superfamily
JWR96_RS05930	COG4166	transmembrane transport
JWR96_RS05940	COG0481	GTPase activity
JWR96_RS05945	COG3527	Alpha-acetolactate decarboxylase
JWR96_RS05975	COG3442	glutamine amidotransferase
JWR96_RS05985	COG1136	(ABC) transporter
JWR96_RS05990	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
JWR96_RS06000	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JWR96_RS06005	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JWR96_RS06010	COG0038	chloride channel
JWR96_RS06015	COG4224	UPF0291 protein
JWR96_RS06030	COG0737	Belongs to the 5'-nucleotidase family
JWR96_RS06045	COG1739	Uncharacterized protein family UPF0029
JWR96_RS06065	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
JWR96_RS06070	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JWR96_RS06080	COG1702	phosphate starvation-inducible protein PhoH
JWR96_RS06085	COG1914	H( )-stimulated, divalent metal cation uptake system
JWR96_RS06090	COG0211	Belongs to the bacterial ribosomal protein bL27 family
JWR96_RS06100	COG0261	This protein binds to 23S rRNA in the presence of protein L20
JWR96_RS06115	COG1078	dGTPase activity
JWR96_RS06130	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JWR96_RS06135	COG2384	SAM-dependent methyltransferase
JWR96_RS06140	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JWR96_RS06160	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JWR96_RS06165	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JWR96_RS06175	COG0488	(ABC) transporter
JWR96_RS06180	COG1393	Belongs to the ArsC family
JWR96_RS06205	COG2003	Belongs to the UPF0758 family
JWR96_RS06210	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JWR96_RS06215	COG0671	phosphoesterase, PA-phosphatase related
JWR96_RS06220	COG5002	protein histidine kinase activity
JWR96_RS06230	COG0745	RESPONSE REGULATOR receiver
JWR96_RS06235	COG0463	Glycosyl transferase, family 2
JWR96_RS06245	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
JWR96_RS06250	COG0564	pseudouridine synthase activity
JWR96_RS06270	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
JWR96_RS06275	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JWR96_RS06275	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JWR96_RS06300	COG2153	protein acetylation
JWR96_RS06305	COG2176	DNA-directed DNA polymerase activity
JWR96_RS06315	COG0187	DNA topoisomerase II activity
JWR96_RS06325	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
JWR96_RS06335	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JWR96_RS06340	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JWR96_RS06345	COG2177	Part of the ABC transporter FtsEX involved in
JWR96_RS06350	COG2884	Cell division ATP-binding protein ftsE
JWR96_RS06370	COG2116	formate transmembrane transporter activity
JWR96_RS06380	COG1131	(ABC) transporter
JWR96_RS06390	COG1481	regulation of sporulation
JWR96_RS06395	COG0391	Required for morphogenesis under gluconeogenic growth conditions
JWR96_RS06405	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JWR96_RS06410	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JWR96_RS06450	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JWR96_RS06450	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JWR96_RS06450	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JWR96_RS06455	COG1105	Belongs to the carbohydrate kinase PfkB family
JWR96_RS06460	COG1349	DNA-binding transcription factor activity
JWR96_RS06465	COG1473	amidohydrolase
JWR96_RS06485	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JWR96_RS06505	COG0588	phosphoglycerate mutase activity
JWR96_RS06520	COG3830	Belongs to the UPF0237 family
JWR96_RS06540	COG0557	exoribonuclease II activity
JWR96_RS06550	COG0492	ferredoxin-NADP+ reductase activity
JWR96_RS06560	COG1126	abc transporter atp-binding protein
JWR96_RS06565	COG0765	amino acid transport
JWR96_RS06570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JWR96_RS06585	COG0393	Putative heavy-metal-binding
JWR96_RS06600	COG0813	purine-nucleoside phosphorylase activity
JWR96_RS06610	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
JWR96_RS06625	COG2814	Major facilitator Superfamily
JWR96_RS06640	COG0500	methyltransferase
JWR96_RS06650	COG0187	DNA topoisomerase II activity
JWR96_RS06660	COG2514	catechol 2,3-dioxygenase activity
JWR96_RS06685	COG0281	malic enzyme
JWR96_RS06690	COG0488	(ABC) transporter
JWR96_RS06710	COG0772	Belongs to the SEDS family
JWR96_RS06720	COG0539	negative regulation of cytoplasmic translation
JWR96_RS06730	COG2197	response regulator
JWR96_RS06735	COG4585	Histidine kinase
JWR96_RS06745	COG2151	metal-sulfur cluster biosynthetic enzyme
JWR96_RS06750	COG1511	domain protein
JWR96_RS06765	COG0589	response to stress
JWR96_RS06790	COG1215	transferase activity, transferring glycosyl groups
JWR96_RS06805	COG4319	ketosteroid isomerase
JWR96_RS06810	COG0335	large ribosomal subunit rRNA binding
JWR96_RS06815	COG2357	RelA SpoT domain protein
JWR96_RS06820	COG0583	DNA-binding transcription factor activity
JWR96_RS06830	COG1136	(ABC) transporter
JWR96_RS06835	COG0577	efflux transmembrane transporter activity
JWR96_RS06845	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JWR96_RS06860	COG0275	rRNA processing
JWR96_RS06880	COG0497	DNA recombination
JWR96_RS06885	COG1438	arginine binding
JWR96_RS06890	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
JWR96_RS06915	COG1929	Belongs to the glycerate kinase type-1 family
JWR96_RS06920	COG2610	gluconate transmembrane transporter activity
JWR96_RS06930	COG1722	exodeoxyribonuclease VII activity
JWR96_RS06935	COG1570	exodeoxyribonuclease VII activity
JWR96_RS06940	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JWR96_RS06945	COG2217	Heavy metal translocating P-type atpase
JWR96_RS06975	COG1174	glycine betaine transport
JWR96_RS06985	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JWR96_RS07000	COG0736	holo-[acyl-carrier-protein] synthase activity
JWR96_RS07025	COG1194	a g-specific adenine glycosylase
JWR96_RS07030	COG0322	excinuclease ABC activity
JWR96_RS07035	COG3201	nicotinamide mononucleotide transporter
JWR96_RS07040	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
JWR96_RS07050	COG0745	RESPONSE REGULATOR receiver
JWR96_RS07060	COG0539	negative regulation of cytoplasmic translation
JWR96_RS07065	COG0482	sulfurtransferase activity
JWR96_RS07085	COG2217	Heavy metal translocating P-type atpase
JWR96_RS07090	COG2608	mercury ion transmembrane transporter activity
JWR96_RS07095	COG3682	Transcriptional regulator
JWR96_RS07100	COG1760	l-serine dehydratase
JWR96_RS07105	COG1760	l-serine dehydratase
JWR96_RS07110	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JWR96_RS07115	COG1252	NADH dehydrogenase
JWR96_RS07130	COG2723	6-phospho-beta-galactosidase activity
JWR96_RS07135	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JWR96_RS07155	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JWR96_RS07160	COG0552	protein localization to endoplasmic reticulum
JWR96_RS07170	COG0561	phosphatase activity
JWR96_RS07175	COG1113	amino acid transport
JWR96_RS07195	COG1368	sulfuric ester hydrolase activity
JWR96_RS07215	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JWR96_RS07225	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JWR96_RS07230	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
JWR96_RS07235	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
JWR96_RS07240	COG2910	NAD(P)H-binding
JWR96_RS07245	COG4708	membrane
JWR96_RS07250	COG1028	Short-chain dehydrogenase reductase Sdr
JWR96_RS07260	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JWR96_RS07260	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JWR96_RS07265	COG0708	Exodeoxyribonuclease III
JWR96_RS07275	COG1349	DNA-binding transcription factor activity
JWR96_RS07280	COG1393	Belongs to the ArsC family
JWR96_RS07285	COG1937	Protein conserved in bacteria
JWR96_RS07290	COG0446	pyridine nucleotide-disulphide oxidoreductase
JWR96_RS07295	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JWR96_RS07300	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JWR96_RS07330	COG0439	Biotin carboxylase
JWR96_RS07345	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JWR96_RS07350	COG1028	Short-chain dehydrogenase reductase Sdr
JWR96_RS07355	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
JWR96_RS07360	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JWR96_RS07365	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JWR96_RS07375	COG1482	cell wall glycoprotein biosynthetic process
JWR96_RS07380	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JWR96_RS07395	COG2740	Nucleic-acid-binding protein implicated in transcription termination
JWR96_RS07400	COG0195	Participates in both transcription termination and antitermination
JWR96_RS07405	COG0779	Required for maturation of 30S ribosomal subunits
JWR96_RS07415	COG1346	cytolysis
JWR96_RS07445	COG1160	GTP binding
JWR96_RS07455	COG0778	Nitroreductase
JWR96_RS07460	COG1484	DNA-dependent DNA replication
JWR96_RS07470	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JWR96_RS07475	COG0220	tRNA (guanine-N7-)-methyltransferase activity
JWR96_RS07490	COG0305	Participates in initiation and elongation during chromosome replication
JWR96_RS07505	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JWR96_RS07520	COG0527	aspartate kinase activity
JWR96_RS07525	COG2268	Band 7 protein
JWR96_RS07535	COG0561	phosphatase activity
JWR96_RS07540	COG0252	asparaginase activity
JWR96_RS07550	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
JWR96_RS07555	COG4109	DRTGG domain
JWR96_RS07565	COG1169	isochorismate synthase
JWR96_RS07570	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
JWR96_RS07575	COG0596	Alpha beta hydrolase
JWR96_RS07580	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
JWR96_RS07585	COG0318	PFAM AMP-dependent synthetase and ligase
JWR96_RS07590	COG4948	Mandelate Racemase Muconate Lactonizing
JWR96_RS07600	COG1609	Transcriptional regulator
JWR96_RS07605	COG1501	Belongs to the glycosyl hydrolase 31 family
JWR96_RS07615	COG1653	transport
JWR96_RS07620	COG0395	ABC-type sugar transport system, permease component
JWR96_RS07625	COG4209	transmembrane transport
JWR96_RS07650	COG1234	tRNA 3'-trailer cleavage
JWR96_RS07675	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JWR96_RS07700	COG0586	Pfam SNARE associated Golgi protein
JWR96_RS07710	COG1132	(ABC) transporter
JWR96_RS07725	COG1846	Transcriptional regulator
JWR96_RS07735	COG4988	ABC transporter
JWR96_RS07740	COG1294	oxidase, subunit
JWR96_RS07745	COG1271	oxidase subunit
JWR96_RS07750	COG3104	oligopeptide transport
JWR96_RS07755	COG1266	CAAX protease self-immunity
JWR96_RS07775	COG0058	SHG alpha-glucan phosphorylase activity
JWR96_RS07780	COG0297	glycogen (starch) synthase activity
JWR96_RS07785	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JWR96_RS07795	COG1640	4-alpha-glucanotransferase
JWR96_RS07800	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JWR96_RS07810	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JWR96_RS07815	COG0006	proline dipeptidase activity
JWR96_RS07820	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
JWR96_RS07825	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
JWR96_RS07835	COG0084	hydrolase, TatD family'
JWR96_RS07900	COG2261	transglycosylase associated protein
JWR96_RS07910	COG1278	Cold shock
JWR96_RS07950	COG3592	Divergent 4Fe-4S mono-cluster
JWR96_RS07960	COG1114	Component of the transport system for branched-chain amino acids
JWR96_RS07965	COG0726	polysaccharide deacetylase
JWR96_RS07975	COG1215	transferase activity, transferring glycosyl groups
JWR96_RS07985	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JWR96_RS07995	COG1393	Belongs to the ArsC family
JWR96_RS08005	COG0740	serine-type endopeptidase activity
JWR96_RS08015	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
JWR96_RS08020	COG0372	Belongs to the citrate synthase family
JWR96_RS08025	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
JWR96_RS08030	COG0772	Belongs to the SEDS family
JWR96_RS08035	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JWR96_RS08040	COG2814	Major facilitator Superfamily
JWR96_RS08045	COG0237	dephospho-CoA kinase activity
JWR96_RS08050	COG1882	Formate acetyltransferase
JWR96_RS08060	COG0318	PFAM AMP-dependent synthetase and ligase
JWR96_RS08070	COG0577	efflux transmembrane transporter activity
JWR96_RS08080	COG0148	phosphopyruvate hydratase activity
JWR96_RS08085	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JWR96_RS08090	COG0542	response to heat
JWR96_RS08100	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JWR96_RS08105	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JWR96_RS08115	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JWR96_RS08120	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
JWR96_RS08120	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
JWR96_RS08125	COG0300	oxidoreductase activity
JWR96_RS08180	COG3158	transport of potassium into the cell
JWR96_RS08190	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
JWR96_RS08195	COG4980	gas vesicle protein
JWR96_RS08205	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JWR96_RS08210	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
JWR96_RS08230	COG2246	polysaccharide biosynthetic process
JWR96_RS08240	COG0024	Methionine aminopeptidase
JWR96_RS08250	COG0477	Major facilitator Superfamily
JWR96_RS08255	COG0716	FMN binding
JWR96_RS08265	COG0789	Transcriptional regulator
JWR96_RS08280	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JWR96_RS08285	COG1254	Belongs to the acylphosphatase family
JWR96_RS08290	COG0560	Phosphoserine phosphatase
JWR96_RS08295	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JWR96_RS08310	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JWR96_RS08315	COG0009	L-threonylcarbamoyladenylate synthase
JWR96_RS08325	COG2890	protein-(glutamine-N5) methyltransferase activity
JWR96_RS08330	COG0778	Nitroreductase
JWR96_RS08350	COG1435	thymidine kinase activity
JWR96_RS08370	COG0456	acetyltransferase
JWR96_RS08375	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JWR96_RS08380	COG1942	4-Oxalocrotonate Tautomerase
JWR96_RS08390	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JWR96_RS08395	COG4684	Psort location CytoplasmicMembrane, score
JWR96_RS08405	COG0706	membrane insertase activity
JWR96_RS08410	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
JWR96_RS08415	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JWR96_RS08420	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JWR96_RS08425	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JWR96_RS08435	COG0494	nUDIX hydrolase
JWR96_RS08440	COG0242	peptide deformylase activity
JWR96_RS08445	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JWR96_RS08450	COG1959	2 iron, 2 sulfur cluster binding
JWR96_RS08455	COG0542	response to heat
JWR96_RS08475	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JWR96_RS08480	COG0358	DNA primase activity
JWR96_RS08575	COG0544	peptidyl-prolyl cis-trans isomerase activity
JWR96_RS08585	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JWR96_RS08590	COG0483	inositol monophosphate 1-phosphatase activity
JWR96_RS08595	COG4476	Belongs to the UPF0223 family
JWR96_RS08600	COG1393	Belongs to the ArsC family
JWR96_RS08605	COG4474	Belongs to the UPF0398 family
JWR96_RS08610	COG3331	DNA recombination
JWR96_RS08625	COG1705	Flagellar rod assembly protein muramidase FlgJ
JWR96_RS08625	COG1388	LysM domain
JWR96_RS08635	COG4166	transmembrane transport
JWR96_RS08640	COG0791	NLP P60 protein
JWR96_RS08640	COG3883	PFAM NLP P60 protein
JWR96_RS08645	COG1104	cysteine desulfurase activity
JWR96_RS08675	COG2169	Transcriptional regulator
JWR96_RS08680	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JWR96_RS08685	COG0456	acetyltransferase
JWR96_RS08690	COG0776	regulation of translation
JWR96_RS08700	COG1472	Belongs to the glycosyl hydrolase 3 family
JWR96_RS08705	COG2755	lipolytic protein G-D-S-L family
JWR96_RS08710	COG1307	EDD domain protein, DegV family
JWR96_RS08715	COG1272	protein, Hemolysin III
JWR96_RS08720	COG0395	ABC-type sugar transport system, permease component
JWR96_RS08735	COG1554	hydrolase, family 65, central catalytic
JWR96_RS08750	COG1609	Transcriptional regulator
JWR96_RS08755	COG0587	DNA-directed DNA polymerase activity
JWR96_RS08770	COG1428	Deoxynucleoside kinase
JWR96_RS08775	COG1611	Belongs to the LOG family
JWR96_RS08865	COG0504	CTP synthase activity
JWR96_RS08870	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
JWR96_RS08875	COG4475	Protein of unknown function (DUF436)
JWR96_RS08880	COG4720	Psort location CytoplasmicMembrane, score
JWR96_RS08885	COG0351	phosphomethylpyrimidine kinase
JWR96_RS08890	COG0101	tRNA pseudouridine synthase activity
JWR96_RS08900	COG1316	TRANSCRIPTIONal
JWR96_RS08910	COG0802	atpase or kinase
JWR96_RS08925	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JWR96_RS08930	COG1554	hydrolase, family 65, central catalytic
JWR96_RS08935	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JWR96_RS08935	COG1263	PTS System
JWR96_RS08940	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JWR96_RS08940	COG2190	(PTS) system
JWR96_RS08940	COG1263	PTS System
JWR96_RS08945	COG2188	Transcriptional regulator
JWR96_RS08970	COG3842	ATPase activity
JWR96_RS08975	COG1597	lipid kinase activity
JWR96_RS08980	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JWR96_RS08995	COG2723	6-phospho-beta-galactosidase activity
JWR96_RS09000	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JWR96_RS09005	COG1737	Transcriptional regulator
JWR96_RS09010	COG1447	Phosphotransferase system cellobiose-specific component IIA
JWR96_RS09015	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JWR96_RS09020	COG1737	Transcriptional regulator
JWR96_RS09030	COG0513	Belongs to the DEAD box helicase family
JWR96_RS09040	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JWR96_RS09045	COG1966	Carbon starvation protein
JWR96_RS09050	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JWR96_RS09055	COG1304	FMN binding
JWR96_RS09070	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JWR96_RS09075	COG1846	Transcriptional regulator
JWR96_RS09105	COG1774	PSP1 C-terminal conserved region
JWR96_RS09110	COG0470	DNA polymerase III
JWR96_RS09120	COG0745	RESPONSE REGULATOR receiver
JWR96_RS09125	COG5002	protein histidine kinase activity
JWR96_RS09130	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
JWR96_RS09140	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
JWR96_RS09150	COG0446	pyridine nucleotide-disulphide oxidoreductase
JWR96_RS09155	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JWR96_RS09160	COG3118	belongs to the thioredoxin family
JWR96_RS09170	COG1363	Peptidase, m42
JWR96_RS09175	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JWR96_RS09190	COG0025	NhaP-type Na H and K H
JWR96_RS09195	COG1764	response to oxidative stress
JWR96_RS09205	COG2814	Major facilitator Superfamily
JWR96_RS09210	COG0301	tRNA thio-modification
JWR96_RS09220	COG0583	DNA-binding transcription factor activity
JWR96_RS09230	COG2855	membrane
JWR96_RS09235	COG0583	DNA-binding transcription factor activity
JWR96_RS09240	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
JWR96_RS09255	COG0833	amino acid
JWR96_RS09265	COG0564	pseudouridine synthase activity
JWR96_RS09270	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JWR96_RS09275	COG2357	RelA SpoT domain protein
JWR96_RS09305	COG1113	amino acid transport
JWR96_RS09310	COG1113	amino acid transport
JWR96_RS09315	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JWR96_RS09325	COG0367	asparagine synthase
JWR96_RS09330	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JWR96_RS09335	COG0513	Belongs to the DEAD box helicase family
JWR96_RS09345	COG4608	Belongs to the ABC transporter superfamily
JWR96_RS09350	COG0444	Belongs to the ABC transporter superfamily
JWR96_RS09355	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JWR96_RS09360	COG0601	transmembrane transport
JWR96_RS09365	COG4166	transmembrane transport
JWR96_RS09370	COG4166	transmembrane transport
JWR96_RS09375	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JWR96_RS09385	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JWR96_RS09390	COG0768	penicillin binding
JWR96_RS09395	COG3634	alkyl hydroperoxide reductase activity
JWR96_RS09400	COG0450	alkyl hydroperoxide reductase
JWR96_RS09405	COG0588	phosphoglycerate mutase activity
JWR96_RS09410	COG0346	lactoylglutathione lyase activity
JWR96_RS09415	COG1733	regulation of RNA biosynthetic process
JWR96_RS09420	COG0656	L-ascorbic acid biosynthetic process
JWR96_RS09425	COG2814	Major facilitator Superfamily
JWR96_RS09435	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JWR96_RS09440	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JWR96_RS09445	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JWR96_RS09450	COG1120	ATPase activity
JWR96_RS09460	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JWR96_RS09465	COG1122	ATPase activity
JWR96_RS09475	COG2011	ABC-type metal ion transport system permease component
JWR96_RS09485	COG1464	Belongs to the NlpA lipoprotein family
JWR96_RS09495	COG1464	Belongs to the NlpA lipoprotein family
JWR96_RS09505	COG1464	Belongs to the NlpA lipoprotein family
JWR96_RS09510	COG3859	Proton-coupled thiamine transporter YuaJ
JWR96_RS09515	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JWR96_RS09520	COG1268	BioY protein
JWR96_RS09535	COG0010	Belongs to the arginase family
JWR96_RS09550	COG4443	Transcriptional Coactivator p15 (PC4)
JWR96_RS09555	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JWR96_RS09560	COG1132	(ABC) transporter
JWR96_RS09565	COG1132	(ABC) transporter
JWR96_RS09575	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JWR96_RS09580	COG1846	Transcriptional regulator
JWR96_RS09600	COG0737	Belongs to the 5'-nucleotidase family
JWR96_RS09605	COG3639	organic phosphonate transmembrane transporter activity
JWR96_RS09645	COG0456	acetyltransferase
JWR96_RS09660	COG5503	Protein of unknown function (DUF1447)
JWR96_RS09680	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
JWR96_RS09685	COG3091	SprT-like family
JWR96_RS09690	COG2183	response to ionizing radiation
JWR96_RS09695	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JWR96_RS09715	COG0726	polysaccharide deacetylase
JWR96_RS09720	COG1473	amidohydrolase
JWR96_RS09725	COG2171	N-acyltransferase activity
JWR96_RS09735	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JWR96_RS09740	COG1122	ATPase activity
JWR96_RS09745	COG1122	ATPase activity
JWR96_RS09780	COG1328	CTP reductase activity
JWR96_RS09785	COG1705	Flagellar rod assembly protein muramidase FlgJ
JWR96_RS09785	COG1388	LysM domain
JWR96_RS09800	COG1335	isochorismatase
JWR96_RS09805	COG0656	L-ascorbic acid biosynthetic process
JWR96_RS09815	COG1854	S-ribosylhomocysteine lyase activity
JWR96_RS09825	COG0673	inositol 2-dehydrogenase activity
JWR96_RS09850	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
JWR96_RS09855	COG2081	HI0933 family
JWR96_RS09865	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
JWR96_RS09870	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JWR96_RS09880	COG1131	(ABC) transporter
JWR96_RS09885	COG4690	dipeptidase activity
JWR96_RS09890	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JWR96_RS09895	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
JWR96_RS09900	COG1461	Dihydroxyacetone kinase
JWR96_RS09905	COG2376	Dihydroxyacetone kinase
JWR96_RS09910	COG1309	transcriptional regulator
JWR96_RS09915	COG2376	Dihydroxyacetone kinase
JWR96_RS09930	COG0561	phosphatase activity
JWR96_RS09935	COG0828	Belongs to the bacterial ribosomal protein bS21 family
JWR96_RS09940	COG0789	Transcriptional regulator
JWR96_RS09950	COG1309	transcriptional regulator
JWR96_RS09965	COG3321	synthase
JWR96_RS09965	COG1028	Short-chain dehydrogenase reductase Sdr
JWR96_RS09965	COG0604	alcohol dehydrogenase
JWR96_RS09980	COG0217	transcriptional regulatory protein
JWR96_RS09985	COG1323	Belongs to the UPF0348 family
JWR96_RS09990	COG2226	methyltransferase
JWR96_RS09995	COG0799	negative regulation of ribosome biogenesis
JWR96_RS10005	COG1713	HD superfamily hydrolase involved in NAD metabolism
JWR96_RS10015	COG1534	Rna-binding protein
JWR96_RS10025	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JWR96_RS10035	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JWR96_RS10040	COG0517	IMP dehydrogenase activity
JWR96_RS10040	COG0516	GMP reductase activity
JWR96_RS10065	COG0562	UDP-galactopyranose mutase
JWR96_RS10070	COG0438	transferase activity, transferring glycosyl groups
JWR96_RS10080	COG0438	transferase activity, transferring glycosyl groups
JWR96_RS10085	COG1216	Glycosyl transferase, family 2
JWR96_RS10105	COG1216	Glycosyl transferase, family 2
JWR96_RS10105	COG1442	glycosyl transferase family 8
JWR96_RS10125	COG1215	transferase activity, transferring glycosyl groups
JWR96_RS10140	COG1088	dTDP-glucose 4,6-dehydratase activity
JWR96_RS10155	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
JWR96_RS10165	COG0227	Belongs to the bacterial ribosomal protein bL28 family
JWR96_RS10175	COG1461	Dihydroxyacetone kinase
JWR96_RS10205	COG0142	geranyltranstransferase activity
JWR96_RS10220	COG4470	Protein conserved in bacteria
JWR96_RS10225	COG0737	Belongs to the 5'-nucleotidase family
JWR96_RS10230	COG0756	dUTP diphosphatase activity
JWR96_RS10235	COG2723	6-phospho-beta-galactosidase activity
JWR96_RS10250	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JWR96_RS10265	COG0346	lactoylglutathione lyase activity
JWR96_RS10280	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JWR96_RS10305	COG0154	amidase activity
JWR96_RS10315	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
JWR96_RS10320	COG0436	Aminotransferase
JWR96_RS10345	COG1832	CoA-binding protein
JWR96_RS10350	COG2814	Major facilitator Superfamily
JWR96_RS10415	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
JWR96_RS10420	COG1309	transcriptional regulator
JWR96_RS10425	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
JWR96_RS10435	COG0300	oxidoreductase activity
JWR96_RS10445	COG3906	Belongs to the UPF0473 family
JWR96_RS10450	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JWR96_RS10455	COG4472	Bacterial protein of unknown function (DUF965)
JWR96_RS10460	COG1266	CAAX protease self-immunity
JWR96_RS10475	COG4989	oxidoreductase activity
JWR96_RS10480	COG0230	Belongs to the bacterial ribosomal protein bL34 family
JWR96_RS10485	COG1847	R3H domain protein
JWR96_RS10490	COG0706	membrane insertase activity
JWR96_RS10495	COG0594	ribonuclease P activity
JWR96_RS10510	COG0165	Argininosuccinate lyase
JWR96_RS10515	COG0137	argininosuccinate synthase activity
JWR96_RS10540	COG0463	Glycosyl transferase, family 2
JWR96_RS10545	COG2814	Major facilitator Superfamily
JWR96_RS10580	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JWR96_RS10600	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
JWR96_RS10605	COG0653	protein targeting
JWR96_RS10610	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JWR96_RS10620	COG0204	Acyl-transferase
JWR96_RS10625	COG0531	amino acid
JWR96_RS10630	COG1011	Hydrolase
JWR96_RS10645	COG0463	Glycosyl transferase, family 2
JWR96_RS10655	COG0726	polysaccharide deacetylase
JWR96_RS10660	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JWR96_RS10665	COG2264	protein methyltransferase activity
JWR96_RS10685	COG0488	(ABC) transporter
JWR96_RS10695	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JWR96_RS10700	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JWR96_RS10705	COG1475	DNA binding
JWR96_RS10720	COG0333	Belongs to the bacterial ribosomal protein bL32 family
JWR96_RS10725	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JWR96_RS10730	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JWR96_RS10735	COG0346	lactoylglutathione lyase activity
JWR96_RS10740	COG0400	carboxylic ester hydrolase activity
JWR96_RS10755	COG4221	oxidoreductase activity
JWR96_RS10770	COG1309	transcriptional regulator
JWR96_RS10775	COG4221	oxidoreductase activity
JWR96_RS10785	COG0488	(ABC) transporter
JWR96_RS10795	COG0416	fatty acid biosynthetic process
JWR96_RS10810	COG1764	response to oxidative stress
JWR96_RS10815	COG0180	Tryptophanyl-tRNA synthetase
JWR96_RS10825	COG1418	mRNA catabolic process
JWR96_RS10830	COG0584	glycerophosphoryl diester phosphodiesterase
JWR96_RS10835	COG0095	Lipoate-protein ligase
JWR96_RS10850	COG0508	dehydrogenase complex catalyzes the overall conversion of
JWR96_RS10860	COG1381	Involved in DNA repair and RecF pathway recombination
JWR96_RS10865	COG0436	Aminotransferase
JWR96_RS10875	COG3153	acetyltransferase
JWR96_RS10880	COG0659	secondary active sulfate transmembrane transporter activity
JWR96_RS10890	COG0454	-acetyltransferase
JWR96_RS10920	COG0246	Mannitol dehydrogenase
JWR96_RS10925	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
JWR96_RS10935	COG2213	PTS system mannitol-specific
JWR96_RS10980	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JWR96_RS10985	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
JWR96_RS10990	COG0037	tRNA processing
JWR96_RS11010	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
JWR96_RS11015	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JWR96_RS11020	COG0193	aminoacyl-tRNA hydrolase activity
JWR96_RS11040	COG0012	GTP binding
JWR96_RS11055	COG1074	ATP-dependent DNA helicase activity
JWR96_RS11060	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
JWR96_RS11065	COG0592	DNA-directed DNA polymerase activity
JWR96_RS11070	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JWR96_RS11105	COG1242	4 iron, 4 sulfur cluster binding
JWR96_RS11110	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
JWR96_RS11115	COG4975	Glucose uptake
JWR96_RS11120	COG1686	Belongs to the peptidase S11 family
JWR96_RS11135	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
JWR96_RS11140	COG0049	tRNA binding
JWR96_RS11145	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JWR96_RS11170	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JWR96_RS11175	COG0681	Belongs to the peptidase S26 family
JWR96_RS11180	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JWR96_RS11185	COG1136	(ABC) transporter
JWR96_RS11195	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JWR96_RS11200	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
JWR96_RS11255	COG1266	CAAX protease self-immunity
JWR96_RS11285	COG2824	Alkylphosphonate utilization operon protein PhnA
JWR96_RS11290	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JWR96_RS11315	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JWR96_RS11325	COG1187	pseudouridine synthase activity
JWR96_RS11330	COG1309	transcriptional regulator
JWR96_RS11345	COG0589	response to stress
JWR96_RS11350	COG2814	Major facilitator Superfamily
JWR96_RS11355	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JWR96_RS11365	COG0494	nUDIX hydrolase
JWR96_RS11380	COG3883	PFAM NLP P60 protein
JWR96_RS11380	COG3942	CHAP domain
JWR96_RS11385	COG0367	asparagine synthase
JWR96_RS11395	COG1794	racemase activity, acting on amino acids and derivatives
JWR96_RS11405	COG0484	heat shock protein binding
JWR96_RS11410	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
JWR96_RS11415	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JWR96_RS11425	COG0730	response to heat
JWR96_RS11445	COG2084	Dehydrogenase
JWR96_RS11455	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JWR96_RS11475	COG2255	four-way junction helicase activity
JWR96_RS11480	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JWR96_RS11485	COG0789	Transcriptional regulator
JWR96_RS11490	COG0174	glutamine synthetase
JWR96_RS11505	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
JWR96_RS11505	COG1605	Chorismate mutase
JWR96_RS11510	COG1956	GAF domain-containing protein
JWR96_RS11520	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JWR96_RS11525	COG0833	amino acid
JWR96_RS11530	COG1968	undecaprenyl-diphosphatase activity
JWR96_RS11535	COG0360	Binds together with S18 to 16S ribosomal RNA
JWR96_RS11540	COG0629	single-stranded DNA binding
JWR96_RS11545	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JWR96_RS11550	COG1408	metallophosphoesterase
JWR96_RS11565	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
JWR96_RS11570	COG1070	Carbohydrate kinase
JWR96_RS11615	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JWR96_RS11650	COG0525	valine-tRNA ligase activity
JWR96_RS11655	COG1733	regulation of RNA biosynthetic process
JWR96_RS11680	COG0166	Belongs to the GPI family
JWR96_RS11690	COG2814	Major facilitator Superfamily
JWR96_RS11695	COG0742	ribosomal rna small subunit methyltransferase
JWR96_RS11700	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JWR96_RS11705	COG3480	Lon protease (S16) C-terminal proteolytic domain
JWR96_RS11715	COG0535	radical SAM domain protein
JWR96_RS11725	COG1396	sequence-specific DNA binding
JWR96_RS11755	COG4716	Myosin-crossreactive antigen
JWR96_RS11765	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
JWR96_RS11770	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JWR96_RS11775	COG3590	peptidase
JWR96_RS11785	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JWR96_RS11790	COG0601	transmembrane transport
JWR96_RS11795	COG4608	Belongs to the ABC transporter superfamily
JWR96_RS11800	COG0444	Belongs to the ABC transporter superfamily
JWR96_RS11835	COG1192	Involved in chromosome partitioning
JWR96_RS11860	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JWR96_RS11930	COG3867	Arabinogalactan endo-beta-1,4-galactanase
JWR96_RS11940	COG2801	Transposase and inactivated derivatives
JWR96_RS11955	COG4221	oxidoreductase activity
JWR96_RS11960	COG0604	alcohol dehydrogenase
JWR96_RS11970	COG0589	response to stress
JWR96_RS12005	COG3867	Arabinogalactan endo-beta-1,4-galactanase
JWR96_RS12025	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JWR96_RS12030	COG1780	Probably involved in ribonucleotide reductase function
JWR96_RS12035	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JWR96_RS12045	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JWR96_RS12050	COG1113	amino acid transport
JWR96_RS12080	COG0390	transport system, permease component
JWR96_RS12085	COG4619	ABC transporter
JWR96_RS12100	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JWR96_RS12105	COG0569	domain protein
JWR96_RS12125	COG0277	FAD linked oxidase domain protein
JWR96_RS12165	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JWR96_RS12200	COG2261	transglycosylase associated protein