locus-tag	class	description
LLUC109_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LLUC109_RS00010	COG0592	DNA-directed DNA polymerase activity
LLUC109_RS00035	COG0012	GTP binding
LLUC109_RS00055	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LLUC109_RS00060	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LLUC109_RS00080	COG0037	tRNA processing
LLUC109_RS00085	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
LLUC109_RS00090	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LLUC109_RS00135	COG2213	PTS system mannitol-specific
LLUC109_RS00155	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LLUC109_RS00180	COG0659	secondary active sulfate transmembrane transporter activity
LLUC109_RS00185	COG3153	acetyltransferase
LLUC109_RS00195	COG0436	Aminotransferase
LLUC109_RS00210	COG0508	dehydrogenase complex catalyzes the overall conversion of
LLUC109_RS00225	COG0095	Lipoate-protein ligase
LLUC109_RS00230	COG0584	glycerophosphoryl diester phosphodiesterase
LLUC109_RS00235	COG1418	mRNA catabolic process
LLUC109_RS00250	COG0180	Tryptophanyl-tRNA synthetase
LLUC109_RS00255	COG1764	response to oxidative stress
LLUC109_RS00275	COG0488	(ABC) transporter
LLUC109_RS00285	COG4221	oxidoreductase activity
LLUC109_RS00290	COG1309	transcriptional regulator
LLUC109_RS00305	COG4221	oxidoreductase activity
LLUC109_RS00315	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LLUC109_RS00320	COG0333	Belongs to the bacterial ribosomal protein bL32 family
LLUC109_RS00325	COG2217	Heavy metal translocating P-type atpase
LLUC109_RS00335	COG1475	DNA binding
LLUC109_RS00340	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LLUC109_RS00345	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LLUC109_RS00360	COG0488	(ABC) transporter
LLUC109_RS00385	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LLUC109_RS00390	COG0726	polysaccharide deacetylase
LLUC109_RS00415	COG1011	Hydrolase
LLUC109_RS00420	COG0531	amino acid
LLUC109_RS00425	COG0204	Acyl-transferase
LLUC109_RS00435	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LLUC109_RS00440	COG0653	protein targeting
LLUC109_RS00445	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LLUC109_RS00465	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LLUC109_RS00495	COG2076	Multidrug Resistance protein
LLUC109_RS00500	COG2814	Major facilitator Superfamily
LLUC109_RS00560	COG0594	ribonuclease P activity
LLUC109_RS00565	COG0706	membrane insertase activity
LLUC109_RS00575	COG0230	Belongs to the bacterial ribosomal protein bL34 family
LLUC109_RS00580	COG4989	oxidoreductase activity
LLUC109_RS00590	COG1266	CAAX protease self-immunity
LLUC109_RS00595	COG4472	Bacterial protein of unknown function (DUF965)
LLUC109_RS00605	COG3906	Belongs to the UPF0473 family
LLUC109_RS00615	COG0300	oxidoreductase activity
LLUC109_RS00625	COG1028	Short-chain dehydrogenase reductase Sdr
LLUC109_RS00630	COG1309	transcriptional regulator
LLUC109_RS00635	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LLUC109_RS00710	COG2814	Major facilitator Superfamily
LLUC109_RS00715	COG1832	CoA-binding protein
LLUC109_RS00740	COG0436	Aminotransferase
LLUC109_RS00745	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
LLUC109_RS00755	COG0154	amidase activity
LLUC109_RS00780	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LLUC109_RS00795	COG0346	lactoylglutathione lyase activity
LLUC109_RS00810	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LLUC109_RS00825	COG2723	6-phospho-beta-galactosidase activity
LLUC109_RS00830	COG0756	dUTP diphosphatase activity
LLUC109_RS00835	COG0737	Belongs to the 5'-nucleotidase family
LLUC109_RS00840	COG4470	Protein conserved in bacteria
LLUC109_RS00845	COG0820	rRNA (adenine-C2-)-methyltransferase activity
LLUC109_RS00855	COG0142	geranyltranstransferase activity
LLUC109_RS00885	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LLUC109_RS00890	COG1461	Dihydroxyacetone kinase
LLUC109_RS00900	COG0227	Belongs to the bacterial ribosomal protein bL28 family
LLUC109_RS00910	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LLUC109_RS00930	COG1088	dTDP-glucose 4,6-dehydratase activity
LLUC109_RS00950	COG0463	Glycosyl transferase, family 2
LLUC109_RS00970	COG1442	glycosyl transferase family 8
LLUC109_RS00970	COG1216	Glycosyl transferase, family 2
LLUC109_RS01005	COG1216	Glycosyl transferase, family 2
LLUC109_RS01005	COG1442	glycosyl transferase family 8
LLUC109_RS01010	COG1216	Glycosyl transferase, family 2
LLUC109_RS01010	COG1442	glycosyl transferase family 8
LLUC109_RS01015	COG1216	Glycosyl transferase, family 2
LLUC109_RS01015	COG1442	glycosyl transferase family 8
LLUC109_RS01020	COG3475	LICD family
LLUC109_RS01035	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
LLUC109_RS01055	COG0516	GMP reductase activity
LLUC109_RS01055	COG0517	IMP dehydrogenase activity
LLUC109_RS01060	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LLUC109_RS01070	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LLUC109_RS01075	COG1534	Rna-binding protein
LLUC109_RS01085	COG1713	HD superfamily hydrolase involved in NAD metabolism
LLUC109_RS01095	COG0799	negative regulation of ribosome biogenesis
LLUC109_RS01100	COG2226	methyltransferase
LLUC109_RS01105	COG1323	Belongs to the UPF0348 family
LLUC109_RS01115	COG0217	transcriptional regulatory protein
LLUC109_RS01125	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LLUC109_RS01135	COG1309	transcriptional regulator
LLUC109_RS01145	COG0789	Transcriptional regulator
LLUC109_RS01150	COG0828	Belongs to the bacterial ribosomal protein bS21 family
LLUC109_RS01165	COG0561	phosphatase activity
LLUC109_RS01175	COG2376	Dihydroxyacetone kinase
LLUC109_RS01180	COG1309	transcriptional regulator
LLUC109_RS01185	COG2376	Dihydroxyacetone kinase
LLUC109_RS01190	COG1461	Dihydroxyacetone kinase
LLUC109_RS01195	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
LLUC109_RS01200	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LLUC109_RS01205	COG4690	dipeptidase activity
LLUC109_RS01220	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LLUC109_RS01235	COG2081	HI0933 family
LLUC109_RS01240	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LLUC109_RS01255	COG1132	(ABC) transporter
LLUC109_RS01265	COG0673	inositol 2-dehydrogenase activity
LLUC109_RS01270	COG1854	S-ribosylhomocysteine lyase activity
LLUC109_RS01280	COG0656	L-ascorbic acid biosynthetic process
LLUC109_RS01285	COG1335	isochorismatase
LLUC109_RS01305	COG1328	CTP reductase activity
LLUC109_RS01340	COG1122	ATPase activity
LLUC109_RS01350	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LLUC109_RS01380	COG0726	polysaccharide deacetylase
LLUC109_RS01400	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LLUC109_RS01405	COG2183	response to ionizing radiation
LLUC109_RS01410	COG3091	SprT-like family
LLUC109_RS01415	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LLUC109_RS01435	COG5503	Protein of unknown function (DUF1447)
LLUC109_RS01450	COG0456	acetyltransferase
LLUC109_RS01490	COG3639	organic phosphonate transmembrane transporter activity
LLUC109_RS01495	COG0737	Belongs to the 5'-nucleotidase family
LLUC109_RS01515	COG1846	Transcriptional regulator
LLUC109_RS01520	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LLUC109_RS01530	COG1132	(ABC) transporter
LLUC109_RS01535	COG1132	(ABC) transporter
LLUC109_RS01540	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LLUC109_RS01545	COG4443	Transcriptional Coactivator p15 (PC4)
LLUC109_RS01565	COG1268	BioY protein
LLUC109_RS01570	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LLUC109_RS01705	COG3859	Proton-coupled thiamine transporter YuaJ
LLUC109_RS01710	COG1464	Belongs to the NlpA lipoprotein family
LLUC109_RS01730	COG1464	Belongs to the NlpA lipoprotein family
LLUC109_RS01740	COG2011	ABC-type metal ion transport system permease component
LLUC109_RS01765	COG1120	ATPase activity
LLUC109_RS01770	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LLUC109_RS01775	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LLUC109_RS01780	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LLUC109_RS01795	COG2814	Major facilitator Superfamily
LLUC109_RS01800	COG0656	L-ascorbic acid biosynthetic process
LLUC109_RS01805	COG1733	regulation of RNA biosynthetic process
LLUC109_RS01810	COG0346	lactoylglutathione lyase activity
LLUC109_RS01815	COG0588	phosphoglycerate mutase activity
LLUC109_RS01820	COG0450	alkyl hydroperoxide reductase
LLUC109_RS01825	COG3634	alkyl hydroperoxide reductase activity
LLUC109_RS01835	COG0768	penicillin binding
LLUC109_RS01840	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LLUC109_RS01850	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LLUC109_RS01855	COG4166	transmembrane transport
LLUC109_RS01860	COG4166	transmembrane transport
LLUC109_RS01865	COG0601	transmembrane transport
LLUC109_RS01870	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LLUC109_RS01875	COG0444	Belongs to the ABC transporter superfamily
LLUC109_RS01880	COG4608	Belongs to the ABC transporter superfamily
LLUC109_RS01890	COG0513	Belongs to the DEAD box helicase family
LLUC109_RS01900	COG0367	asparagine synthase
LLUC109_RS01910	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LLUC109_RS01915	COG1113	amino acid transport
LLUC109_RS01920	COG1113	amino acid transport
LLUC109_RS01950	COG2357	RelA SpoT domain protein
LLUC109_RS01960	COG0564	pseudouridine synthase activity
LLUC109_RS01970	COG0833	amino acid
LLUC109_RS02005	COG2855	membrane
LLUC109_RS02015	COG0583	DNA-binding transcription factor activity
LLUC109_RS02030	COG0301	tRNA thio-modification
LLUC109_RS02050	COG1764	response to oxidative stress
LLUC109_RS02055	COG0025	NhaP-type Na H and K H
LLUC109_RS02070	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LLUC109_RS02075	COG1363	Peptidase, m42
LLUC109_RS02085	COG3118	belongs to the thioredoxin family
LLUC109_RS02090	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LLUC109_RS02095	COG0446	pyridine nucleotide-disulphide oxidoreductase
LLUC109_RS02115	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LLUC109_RS02120	COG5002	protein histidine kinase activity
LLUC109_RS02125	COG0745	RESPONSE REGULATOR receiver
LLUC109_RS02135	COG0470	DNA polymerase III
LLUC109_RS02140	COG1774	PSP1 C-terminal conserved region
LLUC109_RS02170	COG1846	Transcriptional regulator
LLUC109_RS02175	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LLUC109_RS02190	COG1304	FMN binding
LLUC109_RS02195	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LLUC109_RS02200	COG1966	Carbon starvation protein
LLUC109_RS02205	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LLUC109_RS02220	COG0513	Belongs to the DEAD box helicase family
LLUC109_RS02235	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LLUC109_RS02240	COG1447	Phosphotransferase system cellobiose-specific component IIA
LLUC109_RS02250	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LLUC109_RS02255	COG2723	6-phospho-beta-galactosidase activity
LLUC109_RS02275	COG1597	lipid kinase activity
LLUC109_RS02280	COG3842	ATPase activity
LLUC109_RS02315	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LLUC109_RS02315	COG2190	(PTS) system
LLUC109_RS02315	COG1263	PTS System
LLUC109_RS02320	COG1263	PTS System
LLUC109_RS02320	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LLUC109_RS02325	COG1554	hydrolase, family 65, central catalytic
LLUC109_RS02330	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LLUC109_RS02345	COG0802	atpase or kinase
LLUC109_RS02370	COG0351	phosphomethylpyrimidine kinase
LLUC109_RS02375	COG4720	Psort location CytoplasmicMembrane, score
LLUC109_RS02390	COG0504	CTP synthase activity
LLUC109_RS02470	COG1611	Belongs to the LOG family
LLUC109_RS02475	COG1428	Deoxynucleoside kinase
LLUC109_RS02490	COG0587	DNA-directed DNA polymerase activity
LLUC109_RS02495	COG1272	protein, Hemolysin III
LLUC109_RS02500	COG1307	EDD domain protein, DegV family
LLUC109_RS02505	COG2755	lipolytic protein G-D-S-L family
LLUC109_RS02510	COG1472	Belongs to the glycosyl hydrolase 3 family
LLUC109_RS02520	COG0776	regulation of translation
LLUC109_RS02525	COG0456	acetyltransferase
LLUC109_RS02530	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LLUC109_RS02535	COG2169	Transcriptional regulator
LLUC109_RS02580	COG1104	cysteine desulfurase activity
LLUC109_RS02585	COG3883	PFAM NLP P60 protein
LLUC109_RS02585	COG0791	NLP P60 protein
LLUC109_RS02590	COG4166	transmembrane transport
LLUC109_RS02600	COG1705	Flagellar rod assembly protein muramidase FlgJ
LLUC109_RS02600	COG1388	LysM domain
LLUC109_RS02620	COG4474	Belongs to the UPF0398 family
LLUC109_RS02625	COG1393	Belongs to the ArsC family
LLUC109_RS02630	COG4476	Belongs to the UPF0223 family
LLUC109_RS02635	COG0483	inositol monophosphate 1-phosphatase activity
LLUC109_RS02640	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LLUC109_RS02755	COG0358	DNA primase activity
LLUC109_RS02760	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LLUC109_RS02790	COG0542	response to heat
LLUC109_RS02795	COG1959	2 iron, 2 sulfur cluster binding
LLUC109_RS02805	COG0242	peptide deformylase activity
LLUC109_RS02810	COG0494	nUDIX hydrolase
LLUC109_RS02820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LLUC109_RS02830	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LLUC109_RS02835	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
LLUC109_RS02840	COG0706	membrane insertase activity
LLUC109_RS02850	COG4684	Psort location CytoplasmicMembrane, score
LLUC109_RS02855	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LLUC109_RS02865	COG1942	4-Oxalocrotonate Tautomerase
LLUC109_RS02925	COG1435	thymidine kinase activity
LLUC109_RS02945	COG0778	Nitroreductase
LLUC109_RS02950	COG2890	protein-(glutamine-N5) methyltransferase activity
LLUC109_RS02960	COG0009	L-threonylcarbamoyladenylate synthase
LLUC109_RS02970	COG0741	lytic transglycosylase activity
LLUC109_RS02980	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LLUC109_RS02985	COG0560	Phosphoserine phosphatase
LLUC109_RS02995	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LLUC109_RS03010	COG0789	Transcriptional regulator
LLUC109_RS03020	COG0716	FMN binding
LLUC109_RS03035	COG0024	Methionine aminopeptidase
LLUC109_RS03045	COG2246	polysaccharide biosynthetic process
LLUC109_RS03070	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
LLUC109_RS03075	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LLUC109_RS03085	COG4980	gas vesicle protein
LLUC109_RS03090	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LLUC109_RS03155	COG0300	oxidoreductase activity
LLUC109_RS03160	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LLUC109_RS03160	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
LLUC109_RS03165	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LLUC109_RS03175	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LLUC109_RS03180	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LLUC109_RS03205	COG0542	response to heat
LLUC109_RS03210	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LLUC109_RS03215	COG0148	phosphopyruvate hydratase activity
LLUC109_RS03225	COG0577	efflux transmembrane transporter activity
LLUC109_RS03235	COG0318	PFAM AMP-dependent synthetase and ligase
LLUC109_RS03245	COG1882	Formate acetyltransferase
LLUC109_RS03250	COG0237	dephospho-CoA kinase activity
LLUC109_RS03255	COG2814	Major facilitator Superfamily
LLUC109_RS03260	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LLUC109_RS03265	COG0772	Belongs to the SEDS family
LLUC109_RS03270	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LLUC109_RS03280	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LLUC109_RS03290	COG0740	serine-type endopeptidase activity
LLUC109_RS03300	COG1393	Belongs to the ArsC family
LLUC109_RS03335	COG0726	polysaccharide deacetylase
LLUC109_RS03340	COG1114	Component of the transport system for branched-chain amino acids
LLUC109_RS03350	COG3592	Divergent 4Fe-4S mono-cluster
LLUC109_RS03355	COG0084	hydrolase, TatD family'
LLUC109_RS03365	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LLUC109_RS03370	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LLUC109_RS03375	COG0006	proline dipeptidase activity
LLUC109_RS03380	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LLUC109_RS03390	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LLUC109_RS03405	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LLUC109_RS03410	COG0297	glycogen (starch) synthase activity
LLUC109_RS03435	COG1266	CAAX protease self-immunity
LLUC109_RS03440	COG3104	oligopeptide transport
LLUC109_RS03445	COG1271	oxidase subunit
LLUC109_RS03450	COG1294	oxidase, subunit
LLUC109_RS03455	COG4988	ABC transporter
LLUC109_RS03460	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LLUC109_RS03465	COG1846	Transcriptional regulator
LLUC109_RS03490	COG0586	Pfam SNARE associated Golgi protein
LLUC109_RS03515	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LLUC109_RS03540	COG1234	tRNA 3'-trailer cleavage
LLUC109_RS03570	COG0395	ABC-type sugar transport system, permease component
LLUC109_RS03575	COG1653	transport
LLUC109_RS03590	COG1609	Transcriptional regulator
LLUC109_RS03600	COG4948	Mandelate Racemase Muconate Lactonizing
LLUC109_RS03605	COG0318	PFAM AMP-dependent synthetase and ligase
LLUC109_RS03610	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LLUC109_RS03615	COG2267	carboxylic ester hydrolase activity
LLUC109_RS03625	COG1169	isochorismate synthase
LLUC109_RS03635	COG4109	DRTGG domain
LLUC109_RS03640	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LLUC109_RS03650	COG0252	asparaginase activity
LLUC109_RS03655	COG0561	phosphatase activity
LLUC109_RS03665	COG2268	Band 7 protein
LLUC109_RS03670	COG0527	aspartate kinase activity
LLUC109_RS03685	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LLUC109_RS03700	COG0305	Participates in initiation and elongation during chromosome replication
LLUC109_RS03720	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LLUC109_RS03730	COG1484	DNA-dependent DNA replication
LLUC109_RS03735	COG0778	Nitroreductase
LLUC109_RS03745	COG1160	GTP binding
LLUC109_RS03795	COG1346	cytolysis
LLUC109_RS03810	COG0195	Participates in both transcription termination and antitermination
LLUC109_RS03815	COG2740	Nucleic-acid-binding protein implicated in transcription termination
LLUC109_RS03830	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LLUC109_RS03835	COG1482	cell wall glycoprotein biosynthetic process
LLUC109_RS03850	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LLUC109_RS03855	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LLUC109_RS03860	COG1028	Short-chain dehydrogenase reductase Sdr
LLUC109_RS03865	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LLUC109_RS03880	COG0439	Biotin carboxylase
LLUC109_RS03910	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LLUC109_RS03915	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LLUC109_RS03920	COG0446	pyridine nucleotide-disulphide oxidoreductase
LLUC109_RS03925	COG1937	Protein conserved in bacteria
LLUC109_RS03930	COG1393	Belongs to the ArsC family
LLUC109_RS03935	COG1349	DNA-binding transcription factor activity
LLUC109_RS03945	COG0708	Exodeoxyribonuclease III
LLUC109_RS03950	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LLUC109_RS03950	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LLUC109_RS03960	COG1028	Short-chain dehydrogenase reductase Sdr
LLUC109_RS03970	COG4708	membrane
LLUC109_RS03995	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LLUC109_RS04000	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LLUC109_RS04005	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LLUC109_RS04015	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LLUC109_RS04030	COG1196	nuclear chromosome segregation
LLUC109_RS04035	COG1368	sulfuric ester hydrolase activity
LLUC109_RS04060	COG0561	phosphatase activity
LLUC109_RS04070	COG0552	protein localization to endoplasmic reticulum
LLUC109_RS04075	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LLUC109_RS04095	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LLUC109_RS04100	COG2723	6-phospho-beta-galactosidase activity
LLUC109_RS04120	COG1252	NADH dehydrogenase
LLUC109_RS04125	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LLUC109_RS04130	COG1760	l-serine dehydratase
LLUC109_RS04135	COG1760	l-serine dehydratase
LLUC109_RS04140	COG3682	Transcriptional regulator
LLUC109_RS04145	COG2608	mercury ion transmembrane transporter activity
LLUC109_RS04150	COG2217	Heavy metal translocating P-type atpase
LLUC109_RS04170	COG0539	negative regulation of cytoplasmic translation
LLUC109_RS04180	COG0745	RESPONSE REGULATOR receiver
LLUC109_RS04185	COG5002	protein histidine kinase activity
LLUC109_RS04195	COG3201	nicotinamide mononucleotide transporter
LLUC109_RS04200	COG0322	excinuclease ABC activity
LLUC109_RS04205	COG1194	a g-specific adenine glycosylase
LLUC109_RS04215	COG0653	protein targeting
LLUC109_RS04255	COG0736	holo-[acyl-carrier-protein] synthase activity
LLUC109_RS04270	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LLUC109_RS04280	COG1174	glycine betaine transport
LLUC109_RS04310	COG2217	Heavy metal translocating P-type atpase
LLUC109_RS04315	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LLUC109_RS04320	COG1570	exodeoxyribonuclease VII activity
LLUC109_RS04335	COG1929	Belongs to the glycerate kinase type-1 family
LLUC109_RS04350	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
LLUC109_RS04355	COG1438	arginine binding
LLUC109_RS04360	COG0497	DNA recombination
LLUC109_RS04385	COG0275	rRNA processing
LLUC109_RS04395	COG0768	penicillin binding
LLUC109_RS04400	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LLUC109_RS04415	COG1136	(ABC) transporter
LLUC109_RS04420	COG0583	DNA-binding transcription factor activity
LLUC109_RS04430	COG2357	RelA SpoT domain protein
LLUC109_RS04435	COG0335	large ribosomal subunit rRNA binding
LLUC109_RS04460	COG1215	transferase activity, transferring glycosyl groups
LLUC109_RS04480	COG0589	response to stress
LLUC109_RS04510	COG2151	metal-sulfur cluster biosynthetic enzyme
LLUC109_RS04515	COG4974	Belongs to the 'phage' integrase family
LLUC109_RS04545	COG4585	Histidine kinase
LLUC109_RS04550	COG2197	response regulator
LLUC109_RS04565	COG0539	negative regulation of cytoplasmic translation
LLUC109_RS04575	COG0772	Belongs to the SEDS family
LLUC109_RS04590	COG0488	(ABC) transporter
LLUC109_RS04595	COG0281	malic enzyme
LLUC109_RS04630	COG0187	DNA topoisomerase II activity
LLUC109_RS04660	COG2814	Major facilitator Superfamily
LLUC109_RS04685	COG1442	glycosyl transferase family 8
LLUC109_RS04705	COG1316	TRANSCRIPTIONal
LLUC109_RS04720	COG0813	purine-nucleoside phosphorylase activity
LLUC109_RS04735	COG0393	Putative heavy-metal-binding
LLUC109_RS04755	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LLUC109_RS04760	COG0765	amino acid transport
LLUC109_RS04765	COG1126	abc transporter atp-binding protein
LLUC109_RS04775	COG0492	ferredoxin-NADP+ reductase activity
LLUC109_RS04785	COG0557	exoribonuclease II activity
LLUC109_RS04815	COG3830	Belongs to the UPF0237 family
LLUC109_RS04830	COG0588	phosphoglycerate mutase activity
LLUC109_RS04850	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LLUC109_RS04860	COG5617	Psort location CytoplasmicMembrane, score
LLUC109_RS04870	COG1473	amidohydrolase
LLUC109_RS04875	COG1349	DNA-binding transcription factor activity
LLUC109_RS04880	COG1105	Belongs to the carbohydrate kinase PfkB family
LLUC109_RS04885	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LLUC109_RS04885	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LLUC109_RS04885	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LLUC109_RS04930	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LLUC109_RS04935	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LLUC109_RS04945	COG0391	Required for morphogenesis under gluconeogenic growth conditions
LLUC109_RS04950	COG1481	regulation of sporulation
LLUC109_RS04960	COG1131	(ABC) transporter
LLUC109_RS04995	COG2884	Cell division ATP-binding protein ftsE
LLUC109_RS05000	COG2177	Part of the ABC transporter FtsEX involved in
LLUC109_RS05005	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LLUC109_RS05010	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LLUC109_RS05020	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LLUC109_RS05030	COG0187	DNA topoisomerase II activity
LLUC109_RS05040	COG2176	DNA-directed DNA polymerase activity
LLUC109_RS05080	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LLUC109_RS05080	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LLUC109_RS05085	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
LLUC109_RS05110	COG0564	pseudouridine synthase activity
LLUC109_RS05125	COG0463	Glycosyl transferase, family 2
LLUC109_RS05130	COG0745	RESPONSE REGULATOR receiver
LLUC109_RS05140	COG5002	protein histidine kinase activity
LLUC109_RS05145	COG0671	phosphoesterase, PA-phosphatase related
LLUC109_RS05150	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LLUC109_RS05160	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LLUC109_RS05165	COG1393	Belongs to the ArsC family
LLUC109_RS05170	COG0488	(ABC) transporter
LLUC109_RS05180	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LLUC109_RS05205	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LLUC109_RS05210	COG2384	SAM-dependent methyltransferase
LLUC109_RS05215	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LLUC109_RS05230	COG1078	dGTPase activity
LLUC109_RS05245	COG0261	This protein binds to 23S rRNA in the presence of protein L20
LLUC109_RS05255	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LLUC109_RS05265	COG1702	phosphate starvation-inducible protein PhoH
LLUC109_RS05275	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LLUC109_RS05280	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LLUC109_RS05300	COG1739	Uncharacterized protein family UPF0029
LLUC109_RS05315	COG0737	Belongs to the 5'-nucleotidase family
LLUC109_RS05340	COG0038	chloride channel
LLUC109_RS05345	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LLUC109_RS05355	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LLUC109_RS05370	COG1136	(ABC) transporter
LLUC109_RS05380	COG3442	glutamine amidotransferase
LLUC109_RS05385	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LLUC109_RS05390	COG3527	Alpha-acetolactate decarboxylase
LLUC109_RS05400	COG0702	epimerase
LLUC109_RS05435	COG3764	Sortase (surface protein transpeptidase)
LLUC109_RS05455	COG0210	DNA helicase
LLUC109_RS05465	COG0519	Catalyzes the synthesis of GMP from XMP
LLUC109_RS05475	COG1053	succinate dehydrogenase
LLUC109_RS05530	COG0196	riboflavin kinase activity
LLUC109_RS05535	COG0039	L-malate dehydrogenase activity
LLUC109_RS05545	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LLUC109_RS05550	COG1263	PTS System
LLUC109_RS05550	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LLUC109_RS05555	COG1737	Transcriptional regulator
LLUC109_RS05585	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LLUC109_RS05605	COG0647	UMP catabolic process
LLUC109_RS05650	COG2233	PERMEase
LLUC109_RS05660	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LLUC109_RS05665	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LLUC109_RS05690	COG0302	gtp cyclohydrolase
LLUC109_RS05690	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LLUC109_RS05695	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LLUC109_RS05705	COG0285	dihydrofolate synthase activity
LLUC109_RS05710	COG1428	Deoxynucleoside kinase
LLUC109_RS05740	COG1176	ABC-type spermidine putrescine transport system, permease component I
LLUC109_RS05745	COG1177	transmembrane transport
LLUC109_RS05770	COG3507	Belongs to the glycosyl hydrolase 43 family
LLUC109_RS05795	COG1393	Belongs to the ArsC family
LLUC109_RS05805	COG0656	L-ascorbic acid biosynthetic process
LLUC109_RS05835	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LLUC109_RS05840	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
LLUC109_RS05845	COG2226	methyltransferase
LLUC109_RS05850	COG0628	permease
LLUC109_RS05860	COG0028	Belongs to the TPP enzyme family
LLUC109_RS05865	COG2814	Major facilitator Superfamily
LLUC109_RS05870	COG1733	regulation of RNA biosynthetic process
LLUC109_RS05885	COG0557	exoribonuclease II activity
LLUC109_RS05925	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LLUC109_RS05935	COG3231	kanamycin kinase activity
LLUC109_RS05940	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LLUC109_RS05955	COG0140	phosphoribosyl-ATP diphosphatase activity
LLUC109_RS05955	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LLUC109_RS05960	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LLUC109_RS05965	COG1054	Belongs to the UPF0176 family
LLUC109_RS05995	COG0473	3-isopropylmalate dehydrogenase activity
LLUC109_RS06020	COG0066	3-isopropylmalate dehydratase activity
LLUC109_RS06025	COG1119	ATPase activity
LLUC109_RS06040	COG0440	acetolactate synthase activity
LLUC109_RS06045	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LLUC109_RS06050	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LLUC109_RS06055	COG3527	Alpha-acetolactate decarboxylase
LLUC109_RS06060	COG0251	oxidation-reduction process
LLUC109_RS06065	COG0758	DNA mediated transformation
LLUC109_RS06070	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LLUC109_RS06130	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LLUC109_RS06135	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
LLUC109_RS06140	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LLUC109_RS06145	COG1696	Membrane protein involved in D-alanine export
LLUC109_RS06150	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LLUC109_RS06165	COG0351	phosphomethylpyrimidine kinase
LLUC109_RS06195	COG2814	Major facilitator Superfamily
LLUC109_RS06215	COG0222	ribosome binding
LLUC109_RS06220	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LLUC109_RS06235	COG3620	sequence-specific DNA binding
LLUC109_RS06240	COG1132	(ABC) transporter
LLUC109_RS06245	COG1132	(ABC) transporter
LLUC109_RS06270	COG1187	pseudouridine synthase activity
LLUC109_RS06275	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LLUC109_RS06285	COG4974	Belongs to the 'phage' integrase family
LLUC109_RS06300	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LLUC109_RS06310	COG3763	UPF0154 protein
LLUC109_RS06320	COG0493	'glutamate synthase
LLUC109_RS06325	COG0069	glutamate synthase activity
LLUC109_RS06325	COG0070	glutamate synthase
LLUC109_RS06325	COG0067	glutamate synthase
LLUC109_RS06330	COG0110	maltose O-acetyltransferase activity
LLUC109_RS06335	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LLUC109_RS06340	COG0668	transmembrane transport
LLUC109_RS06350	COG0531	amino acid
LLUC109_RS06400	COG1349	DNA-binding transcription factor activity
LLUC109_RS06425	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
LLUC109_RS06430	COG0395	ABC-type sugar transport system, permease component
LLUC109_RS06455	COG0803	Belongs to the bacterial solute-binding protein 9 family
LLUC109_RS06480	COG0419	ATPase involved in DNA repair
LLUC109_RS06485	COG0420	3'-5' exonuclease activity
LLUC109_RS06490	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LLUC109_RS06495	COG1393	Belongs to the ArsC family
LLUC109_RS06515	COG1293	RNA-binding protein homologous to eukaryotic snRNP
LLUC109_RS06520	COG2226	methyltransferase
LLUC109_RS06525	COG3845	ABC transporter
LLUC109_RS06530	COG4603	Belongs to the binding-protein-dependent transport system permease family
LLUC109_RS06535	COG1079	Belongs to the binding-protein-dependent transport system permease family
LLUC109_RS06540	COG0039	L-malate dehydrogenase activity
LLUC109_RS06545	COG0469	pyruvate kinase activity
LLUC109_RS06550	COG0205	6-phosphofructokinase activity
LLUC109_RS06565	COG3853	Toxic anion resistance protein (TelA)
LLUC109_RS06575	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LLUC109_RS06595	COG0142	geranyltranstransferase activity
LLUC109_RS06615	COG0167	dihydroorotate dehydrogenase activity
LLUC109_RS06630	COG2814	Major facilitator Superfamily
LLUC109_RS06635	COG2188	Transcriptional regulator
LLUC109_RS06640	COG2723	6-phospho-beta-galactosidase activity
LLUC109_RS06660	COG1175	transmembrane transport
LLUC109_RS06695	COG1187	pseudouridine synthase activity
LLUC109_RS06700	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LLUC109_RS06705	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LLUC109_RS06765	COG0386	Belongs to the glutathione peroxidase family
LLUC109_RS06775	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LLUC109_RS06815	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
LLUC109_RS06820	COG0745	RESPONSE REGULATOR receiver
LLUC109_RS06835	COG2188	Transcriptional regulator
LLUC109_RS06840	COG1744	ABC transporter substrate-binding protein PnrA-like
LLUC109_RS06850	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LLUC109_RS06865	COG2813	Specifically methylates the guanine in position
LLUC109_RS06870	COG1072	(Pantothenic acid kinase))
LLUC109_RS06875	COG3223	Belongs to the PsiE family
LLUC109_RS06890	COG1475	DNA binding
LLUC109_RS06895	COG3969	phosphoadenosine phosphosulfate
LLUC109_RS06915	COG4175	Glycine betaine
LLUC109_RS06915	COG3448	diguanylate cyclase activity
LLUC109_RS06955	COG0135	phosphoribosylanthranilate isomerase activity
LLUC109_RS06960	COG0134	indole-3-glycerol-phosphate synthase activity
LLUC109_RS06980	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LLUC109_RS06985	COG0512	Glutamine amidotransferase of anthranilate synthase
LLUC109_RS06990	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LLUC109_RS06995	COG3759	membrane
LLUC109_RS07000	COG0778	Nitroreductase
LLUC109_RS07025	COG0735	belongs to the Fur family
LLUC109_RS07040	COG4221	oxidoreductase activity
LLUC109_RS07045	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LLUC109_RS07050	COG1846	Transcriptional regulator
LLUC109_RS07075	COG1653	transport
LLUC109_RS07080	COG0395	ABC-type sugar transport system, permease component
LLUC109_RS07085	COG4209	transmembrane transport
LLUC109_RS07090	COG0519	Catalyzes the synthesis of GMP from XMP
LLUC109_RS07090	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LLUC109_RS07110	COG2115	Belongs to the xylose isomerase family
LLUC109_RS07125	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LLUC109_RS07130	COG0561	phosphatase activity
LLUC109_RS07135	COG0151	Belongs to the GarS family
LLUC109_RS07155	COG0138	bifunctional purine biosynthesis protein purh
LLUC109_RS07180	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LLUC109_RS07185	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LLUC109_RS07190	COG0542	response to heat
LLUC109_RS07230	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LLUC109_RS07260	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LLUC109_RS07270	COG4221	oxidoreductase activity
LLUC109_RS07275	COG0477	Major facilitator Superfamily
LLUC109_RS07280	COG1846	Transcriptional regulator
LLUC109_RS07310	COG2723	6-phospho-beta-galactosidase activity
LLUC109_RS07315	COG0698	ribose 5-phosphate isomerase
LLUC109_RS07320	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LLUC109_RS07325	COG1609	Transcriptional regulator
LLUC109_RS07330	COG1063	alcohol dehydrogenase
LLUC109_RS07345	COG0167	dihydroorotate dehydrogenase activity
LLUC109_RS07350	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LLUC109_RS07355	COG0673	inositol 2-dehydrogenase activity
LLUC109_RS07365	COG0488	(ABC) transporter
LLUC109_RS07375	COG0371	Dehydrogenase
LLUC109_RS07385	COG4690	dipeptidase activity
LLUC109_RS07390	COG0617	tRNA 3'-terminal CCA addition
LLUC109_RS07400	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
LLUC109_RS07405	COG1307	EDD domain protein, DegV family
LLUC109_RS07415	COG0336	Belongs to the RNA methyltransferase TrmD family
LLUC109_RS07435	COG1837	Belongs to the UPF0109 family
LLUC109_RS07440	COG0228	four-way junction DNA binding
LLUC109_RS07450	COG0183	Belongs to the thiolase family
LLUC109_RS07455	COG3425	synthase
LLUC109_RS07460	COG0363	glucosamine-6-phosphate deaminase activity
LLUC109_RS07470	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LLUC109_RS07485	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LLUC109_RS07495	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LLUC109_RS07500	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LLUC109_RS07505	COG0347	Belongs to the P(II) protein family
LLUC109_RS07510	COG0004	ammonium transporteR
LLUC109_RS07515	COG5002	protein histidine kinase activity
LLUC109_RS07520	COG0745	RESPONSE REGULATOR receiver
LLUC109_RS07530	COG0254	rRNA binding
LLUC109_RS07550	COG0505	Belongs to the CarA family
LLUC109_RS07580	COG1230	cation diffusion facilitator family transporter
LLUC109_RS07625	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LLUC109_RS07630	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LLUC109_RS07650	COG1285	pathogenesis
LLUC109_RS07665	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LLUC109_RS07700	COG0800	Aldolase
LLUC109_RS07725	COG1312	Catalyzes the dehydration of D-mannonate
LLUC109_RS07735	COG1802	Transcriptional regulator
LLUC109_RS07740	COG0477	Major facilitator Superfamily
LLUC109_RS07800	COG1869	D-ribose catabolic process
LLUC109_RS07805	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LLUC109_RS07810	COG1609	Transcriptional regulator
LLUC109_RS07815	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LLUC109_RS07835	COG3118	belongs to the thioredoxin family
LLUC109_RS07845	COG1286	toxin biosynthetic process
LLUC109_RS07855	COG1609	Transcriptional regulator
LLUC109_RS07860	COG0006	proline dipeptidase activity
LLUC109_RS07870	COG0116	Belongs to the methyltransferase superfamily
LLUC109_RS07880	COG3599	regulation of cell shape
LLUC109_RS07885	COG1466	dna polymerase III delta subunit
LLUC109_RS07895	COG1674	ftsk spoiiie
LLUC109_RS07900	COG0561	phosphatase activity
LLUC109_RS07910	COG0280	phosphate acetyltransferase
LLUC109_RS07915	COG0572	uridine kinase
LLUC109_RS07925	COG0673	inositol 2-dehydrogenase activity
LLUC109_RS07935	COG0741	lytic transglycosylase activity
LLUC109_RS07985	COG2723	6-phospho-beta-galactosidase activity
LLUC109_RS07995	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LLUC109_RS08000	COG5002	protein histidine kinase activity
LLUC109_RS08005	COG0745	RESPONSE REGULATOR receiver
LLUC109_RS08010	COG1609	Transcriptional regulator
LLUC109_RS08030	COG0110	maltose O-acetyltransferase activity
LLUC109_RS08035	COG0366	Alpha amylase catalytic
LLUC109_RS08040	COG0366	Alpha amylase catalytic
LLUC109_RS08050	COG1175	transmembrane transport
LLUC109_RS08055	COG3833	ABC-type maltose transport systems, permease component
LLUC109_RS08105	COG3715	PTS system
LLUC109_RS08110	COG3716	PTS system mannose fructose sorbose family IID component
LLUC109_RS08130	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LLUC109_RS08145	COG1619	proteins homologs of microcin C7 resistance protein MccF
LLUC109_RS08155	COG0704	Plays a role in the regulation of phosphate uptake
LLUC109_RS08160	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LLUC109_RS08165	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LLUC109_RS08170	COG0581	inorganic phosphate transmembrane transporter activity
LLUC109_RS08175	COG0573	inorganic phosphate transmembrane transporter activity
LLUC109_RS08190	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LLUC109_RS08215	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LLUC109_RS08220	COG4122	O-methyltransferase activity
LLUC109_RS08245	COG2252	PERMEase
LLUC109_RS08250	COG0561	phosphatase activity
LLUC109_RS08255	COG0247	lactate metabolic process
LLUC109_RS08265	COG1556	Lactate utilization protein
LLUC109_RS08270	COG0670	Belongs to the BI1 family
LLUC109_RS08285	COG0268	Binds directly to 16S ribosomal RNA
LLUC109_RS08290	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LLUC109_RS08300	COG0077	Prephenate dehydratase
LLUC109_RS08315	COG0287	Prephenate dehydrogenase
LLUC109_RS08320	COG5002	protein histidine kinase activity
LLUC109_RS08325	COG0745	RESPONSE REGULATOR receiver
LLUC109_RS08335	COG0577	efflux transmembrane transporter activity
LLUC109_RS08340	COG1136	(ABC) transporter
LLUC109_RS08360	COG4493	Belongs to the UPF0637 family
LLUC109_RS08385	COG0765	amino acid transport
LLUC109_RS08390	COG1126	abc transporter atp-binding protein
LLUC109_RS08425	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LLUC109_RS08435	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LLUC109_RS08445	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LLUC109_RS08450	COG0356	it plays a direct role in the translocation of protons across the membrane
LLUC109_RS08490	COG4152	abc transporter atp-binding protein
LLUC109_RS08510	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LLUC109_RS08525	COG1268	BioY protein
LLUC109_RS08545	COG4842	Belongs to the WXG100 family
LLUC109_RS08550	COG0719	Fe-S assembly protein
LLUC109_RS08565	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LLUC109_RS08570	COG0719	Fe-S assembly protein
LLUC109_RS08580	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LLUC109_RS08585	COG4862	establishment of competence for transformation
LLUC109_RS08590	COG1126	abc transporter atp-binding protein
LLUC109_RS08595	COG0765	amino acid transport
LLUC109_RS08600	COG0085	RNA polymerase activity
LLUC109_RS08620	COG1396	sequence-specific DNA binding
LLUC109_RS08625	COG3590	peptidase
LLUC109_RS08635	COG2244	polysaccharide biosynthetic process
LLUC109_RS08650	COG1064	alcohol dehydrogenase
LLUC109_RS08655	COG0514	ATP-dependent DNA helicase (RecQ)
LLUC109_RS08670	COG2195	Cleaves the N-terminal amino acid of tripeptides
LLUC109_RS08680	COG1227	inorganic diphosphatase activity
LLUC109_RS08685	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LLUC109_RS08690	COG1253	flavin adenine dinucleotide binding
LLUC109_RS08695	COG0628	permease
LLUC109_RS08725	COG1573	uracil-dna glycosylase
LLUC109_RS08730	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LLUC109_RS08740	COG2827	Endonuclease containing a URI domain
LLUC109_RS08745	COG1113	amino acid transport
LLUC109_RS08755	COG1564	THIamine pyrophosphokinase
LLUC109_RS08785	COG0436	Aminotransferase
LLUC109_RS08795	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LLUC109_RS08795	COG1199	ATP-dependent helicase activity
LLUC109_RS08810	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LLUC109_RS08815	COG0601	transmembrane transport
LLUC109_RS08820	COG4608	Belongs to the ABC transporter superfamily
LLUC109_RS08825	COG0444	Belongs to the ABC transporter superfamily
LLUC109_RS08830	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LLUC109_RS08835	COG0291	Belongs to the bacterial ribosomal protein bL35 family
LLUC109_RS08840	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LLUC109_RS08875	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
LLUC109_RS08890	COG1045	serine acetyltransferase
LLUC109_RS08910	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LLUC109_RS08915	COG0589	response to stress
LLUC109_RS08920	COG1104	cysteine desulfurase activity
LLUC109_RS08930	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LLUC109_RS08945	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LLUC109_RS08950	COG3599	regulation of cell shape
LLUC109_RS08955	COG2302	S4 RNA-binding domain
LLUC109_RS08970	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LLUC109_RS08975	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LLUC109_RS08980	COG0849	cell division
LLUC109_RS08985	COG1307	EDD domain protein, DegV family
LLUC109_RS09000	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LLUC109_RS09005	COG0656	L-ascorbic acid biosynthetic process
LLUC109_RS09040	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LLUC109_RS09050	COG0494	nUDIX hydrolase
LLUC109_RS09060	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LLUC109_RS09065	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LLUC109_RS09070	COG0515	serine threonine protein kinase
LLUC109_RS09070	COG2815	serine threonine protein kinase
LLUC109_RS09075	COG0631	protein serine/threonine phosphatase activity
LLUC109_RS09080	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LLUC109_RS09080	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LLUC109_RS09090	COG0463	Glycosyl transferase, family 2
LLUC109_RS09110	COG0756	dUTP diphosphatase activity
LLUC109_RS09170	COG2261	transglycosylase associated protein
LLUC109_RS09200	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LLUC109_RS09205	COG1758	RNA polymerase activity
LLUC109_RS09210	COG0194	GDP metabolic process
LLUC109_RS09220	COG0363	glucosamine-6-phosphate deaminase activity
LLUC109_RS09230	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LLUC109_RS09235	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
LLUC109_RS09235	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
LLUC109_RS09255	COG1705	Flagellar rod assembly protein muramidase FlgJ
LLUC109_RS09255	COG3942	CHAP domain
LLUC109_RS09260	COG0191	fructose-bisphosphate aldolase activity
LLUC109_RS09325	COG1070	Carbohydrate kinase
LLUC109_RS09330	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
LLUC109_RS09345	COG1408	metallophosphoesterase
LLUC109_RS09350	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LLUC109_RS09355	COG0629	single-stranded DNA binding
LLUC109_RS09360	COG0360	Binds together with S18 to 16S ribosomal RNA
LLUC109_RS09370	COG0833	amino acid
LLUC109_RS09375	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LLUC109_RS09385	COG1956	GAF domain-containing protein
LLUC109_RS09390	COG1605	Chorismate mutase
LLUC109_RS09390	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
LLUC109_RS09405	COG0174	glutamine synthetase
LLUC109_RS09410	COG0789	Transcriptional regulator
LLUC109_RS09415	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LLUC109_RS09420	COG2255	four-way junction helicase activity
LLUC109_RS09470	COG0730	response to heat
LLUC109_RS09480	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LLUC109_RS09485	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
LLUC109_RS09500	COG1794	racemase activity, acting on amino acids and derivatives
LLUC109_RS09510	COG0367	asparagine synthase
LLUC109_RS09515	COG3883	PFAM NLP P60 protein
LLUC109_RS09515	COG3942	CHAP domain
LLUC109_RS09530	COG0494	nUDIX hydrolase
LLUC109_RS09540	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LLUC109_RS09545	COG2814	Major facilitator Superfamily
LLUC109_RS09550	COG0589	response to stress
LLUC109_RS09565	COG1309	transcriptional regulator
LLUC109_RS09570	COG1187	pseudouridine synthase activity
LLUC109_RS09605	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LLUC109_RS09610	COG2824	Alkylphosphonate utilization operon protein PhnA
LLUC109_RS09640	COG1266	CAAX protease self-immunity
LLUC109_RS09700	COG3421	Type III restriction
LLUC109_RS09705	COG2189	Belongs to the N(4) N(6)-methyltransferase family
LLUC109_RS09745	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LLUC109_RS09750	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LLUC109_RS09760	COG1136	(ABC) transporter
LLUC109_RS09770	COG0681	Belongs to the peptidase S26 family
LLUC109_RS09775	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LLUC109_RS09800	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LLUC109_RS09805	COG0049	tRNA binding
LLUC109_RS09810	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LLUC109_RS09825	COG1686	Belongs to the peptidase S11 family
LLUC109_RS09830	COG4975	Glucose uptake
LLUC109_RS09835	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
LLUC109_RS09840	COG1242	4 iron, 4 sulfur cluster binding
LLUC109_RS09875	COG2860	membrane
LLUC109_RS09900	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LLUC109_RS09910	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
LLUC109_RS09915	COG0626	cystathionine gamma-synthase activity
LLUC109_RS09920	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
LLUC109_RS09940	COG3481	metal-dependent phosphohydrolase, HD sub domain
LLUC109_RS09965	COG1162	GTPase activity
LLUC109_RS09970	COG3584	3D domain protein
LLUC109_RS09970	COG1388	LysM domain
LLUC109_RS09975	COG0072	phenylalanine-tRNA ligase activity
LLUC109_RS09975	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LLUC109_RS09985	COG3479	Phenolic acid decarboxylase
LLUC109_RS10000	COG3469	chitinase activity
LLUC109_RS10005	COG3397	chitin binding
LLUC109_RS10065	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LLUC109_RS10075	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LLUC109_RS10080	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LLUC109_RS10085	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LLUC109_RS10095	COG0537	adenosine 5'-monophosphoramidase activity
LLUC109_RS10125	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LLUC109_RS10130	COG1426	Protein conserved in bacteria
LLUC109_RS10135	COG0612	Peptidase, M16
LLUC109_RS10140	COG0612	Peptidase, M16
LLUC109_RS10145	COG2501	S4 domain
LLUC109_RS10155	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LLUC109_RS10170	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LLUC109_RS10180	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LLUC109_RS10220	COG0826	peptidase U32
LLUC109_RS10235	COG0500	methyltransferase
LLUC109_RS10250	COG1131	(ABC) transporter
LLUC109_RS10270	COG0537	adenosine 5'-monophosphoramidase activity
LLUC109_RS10285	COG0081	regulation of translation
LLUC109_RS10290	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LLUC109_RS10300	COG1131	(ABC) transporter
LLUC109_RS10305	COG4479	Belongs to the UPF0346 family
LLUC109_RS10310	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LLUC109_RS10315	COG2996	Protein conserved in bacteria
LLUC109_RS10340	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LLUC109_RS10345	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LLUC109_RS10350	COG0827	DNA restriction-modification system
LLUC109_RS10360	COG1217	gtp-binding protein TYPA
LLUC109_RS10405	COG1940	carbohydrate kinase activity
LLUC109_RS10415	COG0783	Belongs to the Dps family
LLUC109_RS10445	COG0531	amino acid
LLUC109_RS10460	COG0531	amino acid
LLUC109_RS10465	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LLUC109_RS10470	COG2235	arginine
LLUC109_RS10490	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LLUC109_RS10500	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LLUC109_RS10515	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LLUC109_RS10535	COG1266	CAAX protease self-immunity
LLUC109_RS10550	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
LLUC109_RS10555	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LLUC109_RS10560	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LLUC109_RS10575	COG1335	isochorismatase
LLUC109_RS10615	COG4956	integral membrane protein (PIN domain superfamily)
LLUC109_RS10635	COG1216	Glycosyl transferase, family 2
LLUC109_RS10635	COG1442	glycosyl transferase family 8
LLUC109_RS10640	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LLUC109_RS10645	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
LLUC109_RS10665	COG1216	Glycosyl transferase, family 2
LLUC109_RS10670	COG1216	Glycosyl transferase, family 2
LLUC109_RS10685	COG0203	ribosomal protein L17
LLUC109_RS10690	COG0202	RNA polymerase activity
LLUC109_RS10695	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LLUC109_RS10700	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LLUC109_RS10705	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LLUC109_RS10710	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LLUC109_RS10715	COG0563	adenylate kinase activity
LLUC109_RS10725	COG0200	Binds to the 23S rRNA
LLUC109_RS10730	COG1841	ribosomal large subunit assembly
LLUC109_RS10735	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LLUC109_RS10740	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LLUC109_RS10750	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LLUC109_RS10760	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LLUC109_RS10765	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LLUC109_RS10770	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LLUC109_RS10775	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LLUC109_RS10780	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LLUC109_RS10785	COG0255	Belongs to the universal ribosomal protein uL29 family
LLUC109_RS10790	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LLUC109_RS10795	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LLUC109_RS10800	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LLUC109_RS10805	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LLUC109_RS10810	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LLUC109_RS10825	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LLUC109_RS10830	COG0051	transcription antitermination factor activity, RNA binding
LLUC109_RS10840	COG1970	mechanosensitive ion channel activity
LLUC109_RS10855	COG0250	Participates in transcription elongation, termination and antitermination
LLUC109_RS10865	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LLUC109_RS10870	COG2755	lipolytic protein G-D-S-L family
LLUC109_RS10870	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
LLUC109_RS10875	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LLUC109_RS10880	COG2323	membrane
LLUC109_RS10895	COG0564	pseudouridine synthase activity
LLUC109_RS10905	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LLUC109_RS10910	COG1121	(ABC) transporter
LLUC109_RS10915	COG0803	Belongs to the bacterial solute-binding protein 9 family
LLUC109_RS10915	COG3443	Belongs to the bacterial solute-binding protein 9 family
LLUC109_RS10920	COG1846	Transcriptional regulator
LLUC109_RS10945	COG4537	Required for transformation and DNA binding
LLUC109_RS10950	COG1459	type II secretion system
LLUC109_RS10955	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LLUC109_RS10960	COG2176	DNA-directed DNA polymerase activity
LLUC109_RS10975	COG0442	prolyl-tRNA aminoacylation
LLUC109_RS10980	COG0750	zinc metalloprotease
LLUC109_RS10985	COG4589	Belongs to the CDS family
LLUC109_RS10990	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LLUC109_RS10995	COG1862	Preprotein translocase
LLUC109_RS11010	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LLUC109_RS11020	COG0438	transferase activity, transferring glycosyl groups
LLUC109_RS11035	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
LLUC109_RS11040	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LLUC109_RS11040	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LLUC109_RS11050	COG1609	Transcriptional regulator
LLUC109_RS11080	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
LLUC109_RS11085	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LLUC109_RS11090	COG0052	Belongs to the universal ribosomal protein uS2 family
LLUC109_RS11100	COG2706	6-phosphogluconolactonase activity
LLUC109_RS11105	COG1454	alcohol dehydrogenase
LLUC109_RS11105	COG1012	belongs to the aldehyde dehydrogenase family
LLUC109_RS11130	COG0535	radical SAM domain protein
LLUC109_RS11140	COG3480	Lon protease (S16) C-terminal proteolytic domain
LLUC109_RS11150	COG0742	ribosomal rna small subunit methyltransferase
LLUC109_RS11155	COG2814	Major facilitator Superfamily
LLUC109_RS11195	COG0702	epimerase
LLUC109_RS11200	COG1733	regulation of RNA biosynthetic process
LLUC109_RS11210	COG0525	valine-tRNA ligase activity
LLUC109_RS11245	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LLUC109_RS11295	COG3843	relaxase mobilization nuclease domain protein
LLUC109_RS11335	COG1705	Flagellar rod assembly protein muramidase FlgJ
LLUC109_RS11335	COG3942	CHAP domain
LLUC109_RS11445	COG0745	RESPONSE REGULATOR receiver
LLUC109_RS11450	COG2205	protein histidine kinase activity
LLUC109_RS11500	COG2207	Transcriptional regulator
LLUC109_RS11500	COG3708	Transcriptional regulator
LLUC109_RS11525	COG0454	-acetyltransferase
LLUC109_RS11585	COG1335	isochorismatase
LLUC109_RS11655	COG1278	Cold shock
LLUC109_RS11695	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LLUC109_RS11745	COG1914	H( )-stimulated, divalent metal cation uptake system
LLUC109_RS11770	COG2746	aminoglycoside 3-N-acetyltransferase activity
LLUC109_RS11855	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LLUC109_RS11920	COG4608	Belongs to the ABC transporter superfamily
LLUC109_RS11925	COG0601	transmembrane transport
LLUC109_RS11945	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LLUC109_RS11965	COG3527	Alpha-acetolactate decarboxylase
LLUC109_RS11975	COG3708	Transcriptional regulator
LLUC109_RS11975	COG2207	Transcriptional regulator
LLUC109_RS11985	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LLUC109_RS11995	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LLUC109_RS12025	COG3527	Alpha-acetolactate decarboxylase
LLUC109_RS12230	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline