locus-tag	class	description
LLUC11_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LLUC11_RS00010	COG0592	DNA-directed DNA polymerase activity
LLUC11_RS00015	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
LLUC11_RS00020	COG1074	ATP-dependent DNA helicase activity
LLUC11_RS00035	COG0012	GTP binding
LLUC11_RS00065	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LLUC11_RS00070	COG0193	aminoacyl-tRNA hydrolase activity
LLUC11_RS00075	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LLUC11_RS00085	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LLUC11_RS00105	COG0037	tRNA processing
LLUC11_RS00110	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
LLUC11_RS00115	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LLUC11_RS00160	COG2213	PTS system mannitol-specific
LLUC11_RS00170	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LLUC11_RS00175	COG0246	Mannitol dehydrogenase
LLUC11_RS00195	COG0659	secondary active sulfate transmembrane transporter activity
LLUC11_RS00210	COG0436	Aminotransferase
LLUC11_RS00215	COG1381	Involved in DNA repair and RecF pathway recombination
LLUC11_RS00245	COG0095	Lipoate-protein ligase
LLUC11_RS00250	COG0584	glycerophosphoryl diester phosphodiesterase
LLUC11_RS00255	COG1418	mRNA catabolic process
LLUC11_RS00260	COG0180	Tryptophanyl-tRNA synthetase
LLUC11_RS00265	COG1764	response to oxidative stress
LLUC11_RS00280	COG0416	fatty acid biosynthetic process
LLUC11_RS00290	COG0488	(ABC) transporter
LLUC11_RS00300	COG4221	oxidoreductase activity
LLUC11_RS00315	COG0400	carboxylic ester hydrolase activity
LLUC11_RS00320	COG0346	lactoylglutathione lyase activity
LLUC11_RS00325	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LLUC11_RS00385	COG0489	protein tyrosine kinase activity
LLUC11_RS00390	COG4464	protein tyrosine phosphatase activity
LLUC11_RS00395	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LLUC11_RS00415	COG3475	LICD family
LLUC11_RS00425	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
LLUC11_RS00435	COG0562	UDP-galactopyranose mutase
LLUC11_RS00450	COG1316	TRANSCRIPTIONal
LLUC11_RS00455	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LLUC11_RS00460	COG0333	Belongs to the bacterial ribosomal protein bL32 family
LLUC11_RS00465	COG2217	Heavy metal translocating P-type atpase
LLUC11_RS00470	COG1475	DNA binding
LLUC11_RS00475	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LLUC11_RS00480	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LLUC11_RS00490	COG0488	(ABC) transporter
LLUC11_RS00505	COG2264	protein methyltransferase activity
LLUC11_RS00510	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LLUC11_RS00515	COG0726	polysaccharide deacetylase
LLUC11_RS00525	COG0463	Glycosyl transferase, family 2
LLUC11_RS00530	COG1490	D-aminoacyl-tRNA deacylase activity
LLUC11_RS00540	COG1011	Hydrolase
LLUC11_RS00545	COG0531	amino acid
LLUC11_RS00550	COG0204	Acyl-transferase
LLUC11_RS00560	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LLUC11_RS00565	COG0653	protein targeting
LLUC11_RS00570	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LLUC11_RS00580	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LLUC11_RS00590	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LLUC11_RS00605	COG2076	Multidrug Resistance protein
LLUC11_RS00610	COG2814	Major facilitator Superfamily
LLUC11_RS00615	COG0463	Glycosyl transferase, family 2
LLUC11_RS00630	COG0137	argininosuccinate synthase activity
LLUC11_RS00635	COG0165	Argininosuccinate lyase
LLUC11_RS00650	COG0594	ribonuclease P activity
LLUC11_RS00655	COG0706	membrane insertase activity
LLUC11_RS00665	COG0230	Belongs to the bacterial ribosomal protein bL34 family
LLUC11_RS00670	COG4989	oxidoreductase activity
LLUC11_RS00675	COG4472	Bacterial protein of unknown function (DUF965)
LLUC11_RS00680	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LLUC11_RS00685	COG3906	Belongs to the UPF0473 family
LLUC11_RS00695	COG0300	oxidoreductase activity
LLUC11_RS00705	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
LLUC11_RS00710	COG1309	transcriptional regulator
LLUC11_RS00715	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LLUC11_RS00735	COG0343	queuine tRNA-ribosyltransferase activity
LLUC11_RS00745	COG2814	Major facilitator Superfamily
LLUC11_RS00750	COG1832	CoA-binding protein
LLUC11_RS00775	COG0436	Aminotransferase
LLUC11_RS00780	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
LLUC11_RS00785	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LLUC11_RS00790	COG0154	amidase activity
LLUC11_RS00795	COG1051	belongs to the nudix hydrolase family
LLUC11_RS00800	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LLUC11_RS00820	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LLUC11_RS00845	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LLUC11_RS00860	COG2723	6-phospho-beta-galactosidase activity
LLUC11_RS00865	COG0756	dUTP diphosphatase activity
LLUC11_RS00870	COG0737	Belongs to the 5'-nucleotidase family
LLUC11_RS00875	COG4470	Protein conserved in bacteria
LLUC11_RS00880	COG0820	rRNA (adenine-C2-)-methyltransferase activity
LLUC11_RS00890	COG0142	geranyltranstransferase activity
LLUC11_RS00920	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LLUC11_RS00925	COG1461	Dihydroxyacetone kinase
LLUC11_RS00935	COG0227	Belongs to the bacterial ribosomal protein bL28 family
LLUC11_RS00945	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LLUC11_RS00965	COG1088	dTDP-glucose 4,6-dehydratase activity
LLUC11_RS00985	COG0463	Glycosyl transferase, family 2
LLUC11_RS01005	COG1216	Glycosyl transferase, family 2
LLUC11_RS01005	COG1442	glycosyl transferase family 8
LLUC11_RS01030	COG2244	polysaccharide biosynthetic process
LLUC11_RS01035	COG0438	transferase activity, transferring glycosyl groups
LLUC11_RS01040	COG3475	LICD family
LLUC11_RS01045	COG0438	transferase activity, transferring glycosyl groups
LLUC11_RS01050	COG1215	transferase activity, transferring glycosyl groups
LLUC11_RS01075	COG0516	GMP reductase activity
LLUC11_RS01075	COG0517	IMP dehydrogenase activity
LLUC11_RS01080	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LLUC11_RS01090	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LLUC11_RS01095	COG1534	Rna-binding protein
LLUC11_RS01105	COG1713	HD superfamily hydrolase involved in NAD metabolism
LLUC11_RS01115	COG0799	negative regulation of ribosome biogenesis
LLUC11_RS01120	COG2226	methyltransferase
LLUC11_RS01125	COG1323	Belongs to the UPF0348 family
LLUC11_RS01135	COG0217	transcriptional regulatory protein
LLUC11_RS01145	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LLUC11_RS01160	COG0477	Major facilitator Superfamily
LLUC11_RS01165	COG0789	Transcriptional regulator
LLUC11_RS01170	COG0828	Belongs to the bacterial ribosomal protein bS21 family
LLUC11_RS01175	COG0561	phosphatase activity
LLUC11_RS01185	COG2376	Dihydroxyacetone kinase
LLUC11_RS01190	COG1309	transcriptional regulator
LLUC11_RS01195	COG2376	Dihydroxyacetone kinase
LLUC11_RS01200	COG1461	Dihydroxyacetone kinase
LLUC11_RS01205	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
LLUC11_RS01210	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LLUC11_RS01215	COG4690	dipeptidase activity
LLUC11_RS01225	COG1131	(ABC) transporter
LLUC11_RS01235	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LLUC11_RS01240	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
LLUC11_RS01250	COG2081	HI0933 family
LLUC11_RS01255	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LLUC11_RS01270	COG1132	(ABC) transporter
LLUC11_RS01280	COG0673	inositol 2-dehydrogenase activity
LLUC11_RS01285	COG1854	S-ribosylhomocysteine lyase activity
LLUC11_RS01295	COG0656	L-ascorbic acid biosynthetic process
LLUC11_RS01300	COG1335	isochorismatase
LLUC11_RS01315	COG1388	LysM domain
LLUC11_RS01315	COG1705	Flagellar rod assembly protein muramidase FlgJ
LLUC11_RS01320	COG1328	CTP reductase activity
LLUC11_RS01335	COG0148	phosphopyruvate hydratase activity
LLUC11_RS01345	COG1122	ATPase activity
LLUC11_RS01350	COG1122	ATPase activity
LLUC11_RS01355	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LLUC11_RS01365	COG2171	N-acyltransferase activity
LLUC11_RS01370	COG1473	amidohydrolase
LLUC11_RS01375	COG0726	polysaccharide deacetylase
LLUC11_RS01390	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LLUC11_RS01395	COG2183	response to ionizing radiation
LLUC11_RS01400	COG3091	SprT-like family
LLUC11_RS01405	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LLUC11_RS01425	COG5503	Protein of unknown function (DUF1447)
LLUC11_RS01440	COG0456	acetyltransferase
LLUC11_RS01445	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LLUC11_RS01470	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
LLUC11_RS01480	COG3639	organic phosphonate transmembrane transporter activity
LLUC11_RS01485	COG0737	Belongs to the 5'-nucleotidase family
LLUC11_RS01490	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LLUC11_RS01495	COG0308	aminopeptidase N
LLUC11_RS01505	COG1846	Transcriptional regulator
LLUC11_RS01510	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LLUC11_RS01520	COG1132	(ABC) transporter
LLUC11_RS01525	COG1132	(ABC) transporter
LLUC11_RS01530	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LLUC11_RS01535	COG4443	Transcriptional Coactivator p15 (PC4)
LLUC11_RS01545	COG1268	BioY protein
LLUC11_RS01550	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LLUC11_RS01555	COG3859	Proton-coupled thiamine transporter YuaJ
LLUC11_RS01560	COG1464	Belongs to the NlpA lipoprotein family
LLUC11_RS01570	COG1464	Belongs to the NlpA lipoprotein family
LLUC11_RS01580	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LLUC11_RS01585	COG2011	ABC-type metal ion transport system permease component
LLUC11_RS01590	COG4720	Psort location CytoplasmicMembrane, score
LLUC11_RS01595	COG1122	ATPase activity
LLUC11_RS01610	COG1120	ATPase activity
LLUC11_RS01615	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LLUC11_RS01620	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LLUC11_RS01625	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LLUC11_RS01635	COG2814	Major facilitator Superfamily
LLUC11_RS01640	COG0656	L-ascorbic acid biosynthetic process
LLUC11_RS01645	COG1733	regulation of RNA biosynthetic process
LLUC11_RS01650	COG0346	lactoylglutathione lyase activity
LLUC11_RS01655	COG0588	phosphoglycerate mutase activity
LLUC11_RS01660	COG0450	alkyl hydroperoxide reductase
LLUC11_RS01665	COG3634	alkyl hydroperoxide reductase activity
LLUC11_RS01670	COG0768	penicillin binding
LLUC11_RS01675	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LLUC11_RS01680	COG1181	Belongs to the D-alanine--D-alanine ligase family
LLUC11_RS01685	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LLUC11_RS01690	COG4166	transmembrane transport
LLUC11_RS01695	COG4166	transmembrane transport
LLUC11_RS01700	COG0601	transmembrane transport
LLUC11_RS01705	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LLUC11_RS01710	COG0444	Belongs to the ABC transporter superfamily
LLUC11_RS01715	COG4608	Belongs to the ABC transporter superfamily
LLUC11_RS01720	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LLUC11_RS01725	COG0513	Belongs to the DEAD box helicase family
LLUC11_RS01730	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LLUC11_RS01735	COG0367	asparagine synthase
LLUC11_RS01740	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LLUC11_RS01745	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LLUC11_RS01750	COG1113	amino acid transport
LLUC11_RS01755	COG1113	amino acid transport
LLUC11_RS01765	COG4471	UPF0298 protein
LLUC11_RS01785	COG2357	RelA SpoT domain protein
LLUC11_RS01790	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LLUC11_RS01795	COG0564	pseudouridine synthase activity
LLUC11_RS01805	COG0833	amino acid
LLUC11_RS01820	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LLUC11_RS01825	COG0583	DNA-binding transcription factor activity
LLUC11_RS01830	COG2855	membrane
LLUC11_RS01835	COG0039	L-malate dehydrogenase activity
LLUC11_RS01840	COG0583	DNA-binding transcription factor activity
LLUC11_RS01850	COG0301	tRNA thio-modification
LLUC11_RS01855	COG2814	Major facilitator Superfamily
LLUC11_RS01860	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LLUC11_RS01865	COG1764	response to oxidative stress
LLUC11_RS01870	COG0025	NhaP-type Na H and K H
LLUC11_RS01880	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LLUC11_RS01890	COG1363	Peptidase, m42
LLUC11_RS01900	COG3118	belongs to the thioredoxin family
LLUC11_RS01905	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LLUC11_RS01910	COG0446	pyridine nucleotide-disulphide oxidoreductase
LLUC11_RS01920	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LLUC11_RS01925	COG0459	protein refolding
LLUC11_RS01930	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LLUC11_RS01935	COG5002	protein histidine kinase activity
LLUC11_RS01940	COG0745	RESPONSE REGULATOR receiver
LLUC11_RS01945	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LLUC11_RS01950	COG0470	DNA polymerase III
LLUC11_RS01955	COG1774	PSP1 C-terminal conserved region
LLUC11_RS02055	COG0582	viral genome integration into host DNA
LLUC11_RS02060	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LLUC11_RS02075	COG1304	FMN binding
LLUC11_RS02080	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LLUC11_RS02085	COG1966	Carbon starvation protein
LLUC11_RS02090	COG0513	Belongs to the DEAD box helicase family
LLUC11_RS02100	COG1737	Transcriptional regulator
LLUC11_RS02105	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LLUC11_RS02110	COG1447	Phosphotransferase system cellobiose-specific component IIA
LLUC11_RS02115	COG1737	Transcriptional regulator
LLUC11_RS02125	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LLUC11_RS02130	COG2723	6-phospho-beta-galactosidase activity
LLUC11_RS02145	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LLUC11_RS02150	COG1597	lipid kinase activity
LLUC11_RS02155	COG3842	ATPase activity
LLUC11_RS02175	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LLUC11_RS02180	COG2188	Transcriptional regulator
LLUC11_RS02185	COG1263	PTS System
LLUC11_RS02185	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LLUC11_RS02185	COG2190	(PTS) system
LLUC11_RS02190	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LLUC11_RS02190	COG1263	PTS System
LLUC11_RS02195	COG1554	hydrolase, family 65, central catalytic
LLUC11_RS02200	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LLUC11_RS02205	COG2755	lipolytic protein G-D-S-L family
LLUC11_RS02205	COG0657	acetylesterase activity
LLUC11_RS02220	COG0802	atpase or kinase
LLUC11_RS02230	COG1316	TRANSCRIPTIONal
LLUC11_RS02240	COG0101	tRNA pseudouridine synthase activity
LLUC11_RS02245	COG0351	phosphomethylpyrimidine kinase
LLUC11_RS02250	COG4720	Psort location CytoplasmicMembrane, score
LLUC11_RS02255	COG4475	Protein of unknown function (DUF436)
LLUC11_RS02260	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LLUC11_RS02265	COG0504	CTP synthase activity
LLUC11_RS02290	COG1611	Belongs to the LOG family
LLUC11_RS02295	COG1428	Deoxynucleoside kinase
LLUC11_RS02300	COG0587	DNA-directed DNA polymerase activity
LLUC11_RS02305	COG1272	protein, Hemolysin III
LLUC11_RS02310	COG1307	EDD domain protein, DegV family
LLUC11_RS02315	COG2755	lipolytic protein G-D-S-L family
LLUC11_RS02330	COG0776	regulation of translation
LLUC11_RS02335	COG0456	acetyltransferase
LLUC11_RS02340	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LLUC11_RS02345	COG2169	Transcriptional regulator
LLUC11_RS02370	COG1104	cysteine desulfurase activity
LLUC11_RS02375	COG3883	PFAM NLP P60 protein
LLUC11_RS02375	COG0791	NLP P60 protein
LLUC11_RS02380	COG4166	transmembrane transport
LLUC11_RS02390	COG1388	LysM domain
LLUC11_RS02390	COG1705	Flagellar rod assembly protein muramidase FlgJ
LLUC11_RS02405	COG3331	DNA recombination
LLUC11_RS02410	COG4474	Belongs to the UPF0398 family
LLUC11_RS02415	COG1393	Belongs to the ArsC family
LLUC11_RS02420	COG4476	Belongs to the UPF0223 family
LLUC11_RS02425	COG0483	inositol monophosphate 1-phosphatase activity
LLUC11_RS02430	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LLUC11_RS02440	COG0544	peptidyl-prolyl cis-trans isomerase activity
LLUC11_RS02535	COG0358	DNA primase activity
LLUC11_RS02540	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LLUC11_RS02560	COG0542	response to heat
LLUC11_RS02565	COG1959	2 iron, 2 sulfur cluster binding
LLUC11_RS02570	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LLUC11_RS02575	COG0242	peptide deformylase activity
LLUC11_RS02580	COG0494	nUDIX hydrolase
LLUC11_RS02585	COG0556	nucleotide-excision repair
LLUC11_RS02590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LLUC11_RS02595	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LLUC11_RS02600	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LLUC11_RS02605	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
LLUC11_RS02610	COG0706	membrane insertase activity
LLUC11_RS02620	COG4684	Psort location CytoplasmicMembrane, score
LLUC11_RS02625	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LLUC11_RS02635	COG1942	4-Oxalocrotonate Tautomerase
LLUC11_RS02640	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LLUC11_RS02670	COG1461	Dihydroxyacetone kinase
LLUC11_RS02705	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LLUC11_RS02740	COG1131	(ABC) transporter
LLUC11_RS02760	COG1278	Cold shock
LLUC11_RS02790	COG1396	sequence-specific DNA binding
LLUC11_RS02815	COG0582	viral genome integration into host DNA
LLUC11_RS02820	COG1435	thymidine kinase activity
LLUC11_RS02830	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LLUC11_RS02840	COG0778	Nitroreductase
LLUC11_RS02845	COG2890	protein-(glutamine-N5) methyltransferase activity
LLUC11_RS02855	COG0009	L-threonylcarbamoyladenylate synthase
LLUC11_RS02860	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LLUC11_RS02865	COG0741	lytic transglycosylase activity
LLUC11_RS02870	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LLUC11_RS02875	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LLUC11_RS02880	COG0560	Phosphoserine phosphatase
LLUC11_RS02885	COG1254	Belongs to the acylphosphatase family
LLUC11_RS02890	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LLUC11_RS02900	COG0716	FMN binding
LLUC11_RS02905	COG0477	Major facilitator Superfamily
LLUC11_RS02915	COG0024	Methionine aminopeptidase
LLUC11_RS02925	COG2246	polysaccharide biosynthetic process
LLUC11_RS02945	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
LLUC11_RS02950	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LLUC11_RS02960	COG4980	gas vesicle protein
LLUC11_RS02965	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LLUC11_RS02970	COG3158	transport of potassium into the cell
LLUC11_RS02975	COG3158	transport of potassium into the cell
LLUC11_RS02990	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LLUC11_RS03020	COG1234	tRNA 3'-trailer cleavage
LLUC11_RS03025	COG0300	oxidoreductase activity
LLUC11_RS03030	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LLUC11_RS03030	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
LLUC11_RS03035	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LLUC11_RS03040	COG3343	RNA polymerase activity
LLUC11_RS03045	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LLUC11_RS03050	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LLUC11_RS03055	COG4463	regulation of RNA biosynthetic process
LLUC11_RS03060	COG0542	response to heat
LLUC11_RS03065	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LLUC11_RS03070	COG0148	phosphopyruvate hydratase activity
LLUC11_RS03075	COG4974	Belongs to the 'phage' integrase family
LLUC11_RS03115	COG0148	phosphopyruvate hydratase activity
LLUC11_RS03125	COG0577	efflux transmembrane transporter activity
LLUC11_RS03135	COG0318	PFAM AMP-dependent synthetase and ligase
LLUC11_RS03145	COG1882	Formate acetyltransferase
LLUC11_RS03150	COG0237	dephospho-CoA kinase activity
LLUC11_RS03155	COG2814	Major facilitator Superfamily
LLUC11_RS03160	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LLUC11_RS03165	COG0772	Belongs to the SEDS family
LLUC11_RS03170	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LLUC11_RS03175	COG0372	Belongs to the citrate synthase family
LLUC11_RS03180	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LLUC11_RS03190	COG0740	serine-type endopeptidase activity
LLUC11_RS03200	COG1393	Belongs to the ArsC family
LLUC11_RS03210	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LLUC11_RS03240	COG1114	Component of the transport system for branched-chain amino acids
LLUC11_RS03250	COG3592	Divergent 4Fe-4S mono-cluster
LLUC11_RS03260	COG2801	Transposase and inactivated derivatives
LLUC11_RS03305	COG1131	(ABC) transporter
LLUC11_RS03325	COG3706	GGDEF domain
LLUC11_RS03440	COG1940	carbohydrate kinase activity
LLUC11_RS03445	COG2723	6-phospho-beta-galactosidase activity
LLUC11_RS03460	COG0084	hydrolase, TatD family'
LLUC11_RS03470	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LLUC11_RS03475	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LLUC11_RS03480	COG0006	proline dipeptidase activity
LLUC11_RS03485	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LLUC11_RS03495	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LLUC11_RS03500	COG1640	4-alpha-glucanotransferase
LLUC11_RS03505	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LLUC11_RS03510	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LLUC11_RS03515	COG0297	glycogen (starch) synthase activity
LLUC11_RS03520	COG0058	SHG alpha-glucan phosphorylase activity
LLUC11_RS03530	COG3104	oligopeptide transport
LLUC11_RS03535	COG1271	oxidase subunit
LLUC11_RS03540	COG1294	oxidase, subunit
LLUC11_RS03550	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LLUC11_RS03555	COG1846	Transcriptional regulator
LLUC11_RS03570	COG1132	(ABC) transporter
LLUC11_RS03580	COG0586	Pfam SNARE associated Golgi protein
LLUC11_RS03605	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LLUC11_RS03610	COG1234	tRNA 3'-trailer cleavage
LLUC11_RS03645	COG4948	Mandelate Racemase Muconate Lactonizing
LLUC11_RS03650	COG0318	PFAM AMP-dependent synthetase and ligase
LLUC11_RS03655	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LLUC11_RS03660	COG2267	carboxylic ester hydrolase activity
LLUC11_RS03665	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
LLUC11_RS03670	COG1169	isochorismate synthase
LLUC11_RS03675	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LLUC11_RS03680	COG4109	DRTGG domain
LLUC11_RS03685	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LLUC11_RS03690	COG0252	asparaginase activity
LLUC11_RS03695	COG0561	phosphatase activity
LLUC11_RS03705	COG2268	Band 7 protein
LLUC11_RS03710	COG0527	aspartate kinase activity
LLUC11_RS03720	COG1846	Transcriptional regulator
LLUC11_RS03725	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LLUC11_RS03735	COG0359	binds to the 23S rRNA
LLUC11_RS03740	COG0305	Participates in initiation and elongation during chromosome replication
LLUC11_RS03755	COG0220	tRNA (guanine-N7-)-methyltransferase activity
LLUC11_RS03760	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LLUC11_RS03775	COG1484	DNA-dependent DNA replication
LLUC11_RS03780	COG0778	Nitroreductase
LLUC11_RS03790	COG1160	GTP binding
LLUC11_RS03820	COG1346	cytolysis
LLUC11_RS03830	COG0779	Required for maturation of 30S ribosomal subunits
LLUC11_RS03835	COG0195	Participates in both transcription termination and antitermination
LLUC11_RS03840	COG2740	Nucleic-acid-binding protein implicated in transcription termination
LLUC11_RS03850	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LLUC11_RS03855	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LLUC11_RS03860	COG1482	cell wall glycoprotein biosynthetic process
LLUC11_RS03870	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LLUC11_RS03875	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LLUC11_RS03880	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LLUC11_RS03885	COG1028	Short-chain dehydrogenase reductase Sdr
LLUC11_RS03890	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LLUC11_RS03900	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LLUC11_RS03910	COG0439	Biotin carboxylase
LLUC11_RS03915	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LLUC11_RS03925	COG0626	cystathionine gamma-synthase activity
LLUC11_RS03930	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LLUC11_RS03940	COG1054	Belongs to the UPF0176 family
LLUC11_RS03945	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LLUC11_RS03950	COG0446	pyridine nucleotide-disulphide oxidoreductase
LLUC11_RS03960	COG1393	Belongs to the ArsC family
LLUC11_RS03965	COG1349	DNA-binding transcription factor activity
LLUC11_RS03975	COG0708	Exodeoxyribonuclease III
LLUC11_RS03980	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LLUC11_RS03980	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LLUC11_RS03990	COG1028	Short-chain dehydrogenase reductase Sdr
LLUC11_RS04000	COG4708	membrane
LLUC11_RS04005	COG2910	NAD(P)H-binding
LLUC11_RS04010	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LLUC11_RS04015	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LLUC11_RS04020	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LLUC11_RS04025	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LLUC11_RS04030	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LLUC11_RS04035	COG0571	ribonuclease III activity
LLUC11_RS04040	COG1196	nuclear chromosome segregation
LLUC11_RS04045	COG1368	sulfuric ester hydrolase activity
LLUC11_RS04065	COG1113	amino acid transport
LLUC11_RS04070	COG0561	phosphatase activity
LLUC11_RS04080	COG0552	protein localization to endoplasmic reticulum
LLUC11_RS04085	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LLUC11_RS04095	COG0495	leucyl-tRNA aminoacylation
LLUC11_RS04105	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LLUC11_RS04110	COG2723	6-phospho-beta-galactosidase activity
LLUC11_RS04125	COG1252	NADH dehydrogenase
LLUC11_RS04130	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LLUC11_RS04135	COG1760	l-serine dehydratase
LLUC11_RS04140	COG1760	l-serine dehydratase
LLUC11_RS04145	COG3682	Transcriptional regulator
LLUC11_RS04155	COG2217	Heavy metal translocating P-type atpase
LLUC11_RS04170	COG0482	sulfurtransferase activity
LLUC11_RS04175	COG0539	negative regulation of cytoplasmic translation
LLUC11_RS04180	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
LLUC11_RS04185	COG3201	nicotinamide mononucleotide transporter
LLUC11_RS04190	COG0322	excinuclease ABC activity
LLUC11_RS04205	COG0736	holo-[acyl-carrier-protein] synthase activity
LLUC11_RS04210	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LLUC11_RS04220	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LLUC11_RS04230	COG1174	glycine betaine transport
LLUC11_RS04255	COG2217	Heavy metal translocating P-type atpase
LLUC11_RS04265	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LLUC11_RS04270	COG1570	exodeoxyribonuclease VII activity
LLUC11_RS04275	COG1722	exodeoxyribonuclease VII activity
LLUC11_RS04280	COG1929	Belongs to the glycerate kinase type-1 family
LLUC11_RS04290	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
LLUC11_RS04295	COG1438	arginine binding
LLUC11_RS04300	COG0497	DNA recombination
LLUC11_RS04325	COG0275	rRNA processing
LLUC11_RS04335	COG0768	penicillin binding
LLUC11_RS04340	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LLUC11_RS04350	COG0577	efflux transmembrane transporter activity
LLUC11_RS04355	COG1136	(ABC) transporter
LLUC11_RS04360	COG0583	DNA-binding transcription factor activity
LLUC11_RS04365	COG2357	RelA SpoT domain protein
LLUC11_RS04370	COG0335	large ribosomal subunit rRNA binding
LLUC11_RS04380	COG1215	transferase activity, transferring glycosyl groups
LLUC11_RS04395	COG0589	response to stress
LLUC11_RS04410	COG1511	domain protein
LLUC11_RS04415	COG2151	metal-sulfur cluster biosynthetic enzyme
LLUC11_RS04420	COG0772	Belongs to the SEDS family
LLUC11_RS04425	COG1316	TRANSCRIPTIONal
LLUC11_RS04430	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LLUC11_RS04440	COG4585	Histidine kinase
LLUC11_RS04445	COG2197	response regulator
LLUC11_RS04460	COG0539	negative regulation of cytoplasmic translation
LLUC11_RS04470	COG0772	Belongs to the SEDS family
LLUC11_RS04485	COG0488	(ABC) transporter
LLUC11_RS04490	COG0281	malic enzyme
LLUC11_RS04515	COG0187	DNA topoisomerase II activity
LLUC11_RS04525	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LLUC11_RS04540	COG2814	Major facilitator Superfamily
LLUC11_RS04560	COG1682	transport, permease protein
LLUC11_RS04585	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LLUC11_RS04585	COG1215	transferase activity, transferring glycosyl groups
LLUC11_RS04595	COG0562	UDP-galactopyranose mutase
LLUC11_RS04605	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
LLUC11_RS04615	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LLUC11_RS04615	COG0463	Glycosyl transferase, family 2
LLUC11_RS04625	COG1316	TRANSCRIPTIONal
LLUC11_RS04630	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
LLUC11_RS04640	COG0813	purine-nucleoside phosphorylase activity
LLUC11_RS04650	COG0393	Putative heavy-metal-binding
LLUC11_RS04655	COG2759	Belongs to the formate--tetrahydrofolate ligase family
LLUC11_RS04665	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LLUC11_RS04670	COG0765	amino acid transport
LLUC11_RS04675	COG1126	abc transporter atp-binding protein
LLUC11_RS04685	COG0492	ferredoxin-NADP+ reductase activity
LLUC11_RS04695	COG0557	exoribonuclease II activity
LLUC11_RS04715	COG3830	Belongs to the UPF0237 family
LLUC11_RS04720	COG2848	UPF0210 protein
LLUC11_RS04730	COG0406	alpha-ribazole phosphatase activity
LLUC11_RS04745	COG1420	regulation of RNA biosynthetic process
LLUC11_RS04750	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LLUC11_RS04755	COG0443	Heat shock 70 kDa protein
LLUC11_RS04765	COG1473	amidohydrolase
LLUC11_RS04770	COG1349	DNA-binding transcription factor activity
LLUC11_RS04775	COG1105	Belongs to the carbohydrate kinase PfkB family
LLUC11_RS04780	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LLUC11_RS04780	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LLUC11_RS04780	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LLUC11_RS04785	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LLUC11_RS04790	COG1660	Displays ATPase and GTPase activities
LLUC11_RS04795	COG0391	Required for morphogenesis under gluconeogenic growth conditions
LLUC11_RS04800	COG1481	regulation of sporulation
LLUC11_RS04810	COG1131	(ABC) transporter
LLUC11_RS04825	COG2116	formate transmembrane transporter activity
LLUC11_RS04840	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LLUC11_RS04845	COG2884	Cell division ATP-binding protein ftsE
LLUC11_RS04850	COG2177	Part of the ABC transporter FtsEX involved in
LLUC11_RS04855	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LLUC11_RS04865	COG1780	Probably involved in ribonucleotide reductase function
LLUC11_RS04870	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LLUC11_RS04875	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
LLUC11_RS04880	COG0187	DNA topoisomerase II activity
LLUC11_RS04890	COG2176	DNA-directed DNA polymerase activity
LLUC11_RS04895	COG2153	protein acetylation
LLUC11_RS04920	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LLUC11_RS04920	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LLUC11_RS04925	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
LLUC11_RS04930	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LLUC11_RS04935	COG0564	pseudouridine synthase activity
LLUC11_RS04940	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
LLUC11_RS04950	COG0463	Glycosyl transferase, family 2
LLUC11_RS04955	COG0745	RESPONSE REGULATOR receiver
LLUC11_RS04965	COG5002	protein histidine kinase activity
LLUC11_RS04970	COG0671	phosphoesterase, PA-phosphatase related
LLUC11_RS04975	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LLUC11_RS04980	COG2003	Belongs to the UPF0758 family
LLUC11_RS04985	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LLUC11_RS04995	COG0488	(ABC) transporter
LLUC11_RS05025	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LLUC11_RS05030	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LLUC11_RS05040	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LLUC11_RS05045	COG2384	SAM-dependent methyltransferase
LLUC11_RS05050	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LLUC11_RS05065	COG1078	dGTPase activity
LLUC11_RS05080	COG0261	This protein binds to 23S rRNA in the presence of protein L20
LLUC11_RS05090	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LLUC11_RS05095	COG1914	H( )-stimulated, divalent metal cation uptake system
LLUC11_RS05100	COG1702	phosphate starvation-inducible protein PhoH
LLUC11_RS05110	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LLUC11_RS05115	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LLUC11_RS05130	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
LLUC11_RS05135	COG1739	Uncharacterized protein family UPF0029
LLUC11_RS05155	COG0752	glycyl-tRNA synthetase alpha subunit
LLUC11_RS05160	COG0751	glycine-tRNA ligase activity
LLUC11_RS05165	COG4224	UPF0291 protein
LLUC11_RS05170	COG0038	chloride channel
LLUC11_RS05175	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LLUC11_RS05185	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LLUC11_RS05195	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LLUC11_RS05200	COG1136	(ABC) transporter
LLUC11_RS05210	COG3442	glutamine amidotransferase
LLUC11_RS05215	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LLUC11_RS05220	COG3527	Alpha-acetolactate decarboxylase
LLUC11_RS05225	COG0481	GTPase activity
LLUC11_RS05230	COG0702	epimerase
LLUC11_RS05235	COG0531	amino acid
LLUC11_RS05250	COG3764	Sortase (surface protein transpeptidase)
LLUC11_RS05260	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LLUC11_RS05260	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LLUC11_RS05275	COG0210	DNA helicase
LLUC11_RS05280	COG2816	NAD+ diphosphatase activity
LLUC11_RS05285	COG0519	Catalyzes the synthesis of GMP from XMP
LLUC11_RS05305	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LLUC11_RS05310	COG0196	riboflavin kinase activity
LLUC11_RS05315	COG0039	L-malate dehydrogenase activity
LLUC11_RS05325	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LLUC11_RS05335	COG1737	Transcriptional regulator
LLUC11_RS05340	COG0149	triose-phosphate isomerase activity
LLUC11_RS05355	COG3969	phosphoadenosine phosphosulfate
LLUC11_RS05360	COG1475	DNA binding
LLUC11_RS05365	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LLUC11_RS05395	COG0516	GMP reductase activity
LLUC11_RS05400	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LLUC11_RS05405	COG2233	PERMEase
LLUC11_RS05415	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LLUC11_RS05420	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LLUC11_RS05430	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LLUC11_RS05435	COG0218	Necessary for normal cell division and for the maintenance of normal septation
LLUC11_RS05445	COG0302	gtp cyclohydrolase
LLUC11_RS05445	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LLUC11_RS05450	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LLUC11_RS05455	COG1051	belongs to the nudix hydrolase family
LLUC11_RS05460	COG0285	dihydrofolate synthase activity
LLUC11_RS05465	COG1428	Deoxynucleoside kinase
LLUC11_RS05470	COG0460	homoserine dehydrogenase
LLUC11_RS05475	COG0083	homoserine kinase activity
LLUC11_RS05485	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LLUC11_RS05490	COG3842	ATPase activity
LLUC11_RS05495	COG1176	ABC-type spermidine putrescine transport system, permease component I
LLUC11_RS05500	COG1177	transmembrane transport
LLUC11_RS05510	COG0582	viral genome integration into host DNA
LLUC11_RS05530	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LLUC11_RS05535	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LLUC11_RS05540	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
LLUC11_RS05555	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LLUC11_RS05560	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
LLUC11_RS05565	COG2226	methyltransferase
LLUC11_RS05570	COG0628	permease
LLUC11_RS05580	COG0028	Belongs to the TPP enzyme family
LLUC11_RS05600	COG2205	protein histidine kinase activity
LLUC11_RS05605	COG0745	RESPONSE REGULATOR receiver
LLUC11_RS05615	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
LLUC11_RS05620	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
LLUC11_RS05625	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
LLUC11_RS05640	COG0557	exoribonuclease II activity
LLUC11_RS05645	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LLUC11_RS05650	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
LLUC11_RS05655	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
LLUC11_RS05660	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LLUC11_RS05670	COG0131	Imidazoleglycerol-phosphate dehydratase
LLUC11_RS05675	COG3231	kanamycin kinase activity
LLUC11_RS05680	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LLUC11_RS05685	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LLUC11_RS05690	COG0107	imidazoleglycerol-phosphate synthase activity
LLUC11_RS05695	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LLUC11_RS05695	COG0140	phosphoribosyl-ATP diphosphatase activity
LLUC11_RS05700	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LLUC11_RS05705	COG1054	Belongs to the UPF0176 family
LLUC11_RS05715	COG0473	3-isopropylmalate dehydrogenase activity
LLUC11_RS05725	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LLUC11_RS05730	COG0066	3-isopropylmalate dehydratase activity
LLUC11_RS05735	COG1119	ATPase activity
LLUC11_RS05740	COG0129	dihydroxy-acid dehydratase activity
LLUC11_RS05745	COG0028	Belongs to the TPP enzyme family
LLUC11_RS05750	COG0440	acetolactate synthase activity
LLUC11_RS05755	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LLUC11_RS05760	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LLUC11_RS05765	COG3527	Alpha-acetolactate decarboxylase
LLUC11_RS05770	COG0251	oxidation-reduction process
LLUC11_RS05775	COG0758	DNA mediated transformation
LLUC11_RS05780	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LLUC11_RS05785	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
LLUC11_RS05790	COG4974	Belongs to the 'phage' integrase family
LLUC11_RS05800	COG4974	Belongs to the 'phage' integrase family
LLUC11_RS05810	COG0798	PFAM Bile acid sodium symporter
LLUC11_RS05815	COG0446	pyridine nucleotide-disulphide oxidoreductase
LLUC11_RS05845	COG0446	pyridine nucleotide-disulphide oxidoreductase
LLUC11_RS05850	COG0446	pyridine nucleotide-disulphide oxidoreductase
LLUC11_RS05855	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LLUC11_RS05860	COG3118	belongs to the thioredoxin family
LLUC11_RS05895	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
LLUC11_RS05910	COG3843	relaxase mobilization nuclease domain protein
LLUC11_RS06100	COG4974	Belongs to the 'phage' integrase family
LLUC11_RS06105	COG0686	Belongs to the AlaDH PNT family
LLUC11_RS06130	COG2261	transglycosylase associated protein
LLUC11_RS06140	COG1278	Cold shock
LLUC11_RS06155	COG0656	L-ascorbic acid biosynthetic process
LLUC11_RS06165	COG0789	Transcriptional regulator
LLUC11_RS06170	COG0789	Transcriptional regulator
LLUC11_RS06175	COG0110	maltose O-acetyltransferase activity
LLUC11_RS06180	COG4221	oxidoreductase activity
LLUC11_RS06195	COG1846	Transcriptional regulator
LLUC11_RS06210	COG3976	FMN-binding domain protein
LLUC11_RS06210	COG1053	succinate dehydrogenase
LLUC11_RS06210	COG0431	NADPH-dependent FMN reductase
LLUC11_RS06220	COG1744	ABC transporter substrate-binding protein PnrA-like
LLUC11_RS06230	COG1611	Belongs to the LOG family
LLUC11_RS06235	COG1428	Deoxynucleoside kinase
LLUC11_RS06245	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LLUC11_RS06250	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LLUC11_RS06255	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LLUC11_RS06270	COG0025	NhaP-type Na H and K H
LLUC11_RS06275	COG4641	Protein conserved in bacteria
LLUC11_RS06275	COG0438	transferase activity, transferring glycosyl groups
LLUC11_RS06285	COG1304	FMN binding
LLUC11_RS06290	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LLUC11_RS06295	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LLUC11_RS06300	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LLUC11_RS06310	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LLUC11_RS06315	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
LLUC11_RS06320	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LLUC11_RS06325	COG1696	Membrane protein involved in D-alanine export
LLUC11_RS06330	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LLUC11_RS06340	COG0352	thiamine-phosphate diphosphorylase activity
LLUC11_RS06345	COG0351	phosphomethylpyrimidine kinase
LLUC11_RS06350	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
LLUC11_RS06360	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LLUC11_RS06370	COG0222	ribosome binding
LLUC11_RS06375	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LLUC11_RS06385	COG3620	sequence-specific DNA binding
LLUC11_RS06390	COG1132	(ABC) transporter
LLUC11_RS06395	COG1132	(ABC) transporter
LLUC11_RS06405	COG1187	pseudouridine synthase activity
LLUC11_RS06410	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LLUC11_RS06415	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LLUC11_RS06420	COG4974	Belongs to the 'phage' integrase family
LLUC11_RS06435	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LLUC11_RS06440	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LLUC11_RS06445	COG3763	UPF0154 protein
LLUC11_RS06455	COG0493	'glutamate synthase
LLUC11_RS06460	COG0069	glutamate synthase activity
LLUC11_RS06460	COG0067	glutamate synthase
LLUC11_RS06460	COG0070	glutamate synthase
LLUC11_RS06465	COG0110	maltose O-acetyltransferase activity
LLUC11_RS06470	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LLUC11_RS06475	COG0668	transmembrane transport
LLUC11_RS06480	COG0076	glutamate decarboxylase activity
LLUC11_RS06485	COG0531	amino acid
LLUC11_RS06495	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LLUC11_RS06515	COG1349	DNA-binding transcription factor activity
LLUC11_RS06525	COG3443	Belongs to the bacterial solute-binding protein 9 family
LLUC11_RS06525	COG0803	Belongs to the bacterial solute-binding protein 9 family
LLUC11_RS06545	COG0726	polysaccharide deacetylase
LLUC11_RS06585	COG0406	alpha-ribazole phosphatase activity
LLUC11_RS06590	COG0561	phosphatase activity
LLUC11_RS06595	COG0561	phosphatase activity
LLUC11_RS06600	COG0110	maltose O-acetyltransferase activity
LLUC11_RS06605	COG0346	lactoylglutathione lyase activity
LLUC11_RS06615	COG3961	Belongs to the TPP enzyme family
LLUC11_RS06640	COG0300	oxidoreductase activity
LLUC11_RS06660	COG1393	Belongs to the ArsC family
LLUC11_RS06675	COG0803	Belongs to the bacterial solute-binding protein 9 family
LLUC11_RS06700	COG0419	ATPase involved in DNA repair
LLUC11_RS06705	COG0420	3'-5' exonuclease activity
LLUC11_RS06710	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LLUC11_RS06715	COG1393	Belongs to the ArsC family
LLUC11_RS06730	COG1293	RNA-binding protein homologous to eukaryotic snRNP
LLUC11_RS06735	COG2226	methyltransferase
LLUC11_RS06740	COG3845	ABC transporter
LLUC11_RS06745	COG4603	Belongs to the binding-protein-dependent transport system permease family
LLUC11_RS06750	COG1079	Belongs to the binding-protein-dependent transport system permease family
LLUC11_RS06755	COG0039	L-malate dehydrogenase activity
LLUC11_RS06760	COG0469	pyruvate kinase activity
LLUC11_RS06765	COG0205	6-phosphofructokinase activity
LLUC11_RS06780	COG3853	Toxic anion resistance protein (TelA)
LLUC11_RS06790	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LLUC11_RS06810	COG0142	geranyltranstransferase activity
LLUC11_RS06815	COG0357	Ribosomal RNA small subunit methyltransferase G
LLUC11_RS06825	COG0284	orotidine-5'-phosphate decarboxylase activity
LLUC11_RS06830	COG0167	dihydroorotate dehydrogenase activity
LLUC11_RS06835	COG0543	2 iron, 2 sulfur cluster binding
LLUC11_RS06840	COG2814	Major facilitator Superfamily
LLUC11_RS06845	COG2188	Transcriptional regulator
LLUC11_RS06850	COG2723	6-phospho-beta-galactosidase activity
LLUC11_RS06865	COG1175	transmembrane transport
LLUC11_RS06905	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LLUC11_RS06910	COG0386	Belongs to the glutathione peroxidase family
LLUC11_RS06915	COG1705	Flagellar rod assembly protein muramidase FlgJ
LLUC11_RS06920	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LLUC11_RS06960	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LLUC11_RS06990	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
LLUC11_RS06995	COG0745	RESPONSE REGULATOR receiver
LLUC11_RS07010	COG2188	Transcriptional regulator
LLUC11_RS07015	COG1744	ABC transporter substrate-binding protein PnrA-like
LLUC11_RS07025	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LLUC11_RS07040	COG2813	Specifically methylates the guanine in position
LLUC11_RS07045	COG1072	(Pantothenic acid kinase))
LLUC11_RS07050	COG3223	Belongs to the PsiE family
LLUC11_RS07065	COG1475	DNA binding
LLUC11_RS07070	COG3969	phosphoadenosine phosphosulfate
LLUC11_RS07090	COG3448	diguanylate cyclase activity
LLUC11_RS07090	COG4175	Glycine betaine
LLUC11_RS07120	COG2723	6-phospho-beta-galactosidase activity
LLUC11_RS07125	COG2190	(PTS) system
LLUC11_RS07125	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LLUC11_RS07125	COG1263	PTS System
LLUC11_RS07130	COG3711	transcriptional antiterminator
LLUC11_RS07135	COG0159	tryptophan synthase activity
LLUC11_RS07140	COG0133	tryptophan synthase activity
LLUC11_RS07150	COG0135	phosphoribosylanthranilate isomerase activity
LLUC11_RS07155	COG0134	indole-3-glycerol-phosphate synthase activity
LLUC11_RS07160	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LLUC11_RS07165	COG0512	Glutamine amidotransferase of anthranilate synthase
LLUC11_RS07170	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LLUC11_RS07175	COG3759	membrane
LLUC11_RS07180	COG0778	Nitroreductase
LLUC11_RS07205	COG0735	belongs to the Fur family
LLUC11_RS07215	COG0697	spore germination
LLUC11_RS07220	COG0789	Transcriptional regulator
LLUC11_RS07225	COG4221	oxidoreductase activity
LLUC11_RS07230	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LLUC11_RS07255	COG0519	Catalyzes the synthesis of GMP from XMP
LLUC11_RS07255	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LLUC11_RS07270	COG2723	6-phospho-beta-galactosidase activity
LLUC11_RS07285	COG0366	Alpha amylase catalytic
LLUC11_RS07295	COG1653	transport
LLUC11_RS07300	COG0395	ABC-type sugar transport system, permease component
LLUC11_RS07305	COG1175	transmembrane transport
LLUC11_RS07310	COG0383	alpha-mannosidase activity
LLUC11_RS07330	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
LLUC11_RS07335	COG2160	L-arabinose isomerase activity
LLUC11_RS07340	COG0235	Class ii aldolase
LLUC11_RS07370	COG3507	Belongs to the glycosyl hydrolase 43 family
LLUC11_RS07375	COG2211	Major facilitator Superfamily
LLUC11_RS07385	COG1070	Carbohydrate kinase
LLUC11_RS07390	COG2115	Belongs to the xylose isomerase family
LLUC11_RS07405	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LLUC11_RS07410	COG0151	Belongs to the GarS family
LLUC11_RS07420	COG2814	Major facilitator Superfamily
LLUC11_RS07425	COG1011	Hydrolase
LLUC11_RS07430	COG0138	bifunctional purine biosynthesis protein purh
LLUC11_RS07450	COG1132	(ABC) transporter
LLUC11_RS07455	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LLUC11_RS07460	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LLUC11_RS07465	COG0542	response to heat
LLUC11_RS07490	COG4221	oxidoreductase activity
LLUC11_RS07495	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LLUC11_RS07500	COG0047	phosphoribosylformylglycinamidine synthase activity
LLUC11_RS07510	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
LLUC11_RS07525	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LLUC11_RS07535	COG4221	oxidoreductase activity
LLUC11_RS07540	COG0477	Major facilitator Superfamily
LLUC11_RS07545	COG1846	Transcriptional regulator
LLUC11_RS07550	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LLUC11_RS07570	COG1063	alcohol dehydrogenase
LLUC11_RS07585	COG0167	dihydroorotate dehydrogenase activity
LLUC11_RS07590	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LLUC11_RS07595	COG0673	inositol 2-dehydrogenase activity
LLUC11_RS07605	COG0488	(ABC) transporter
LLUC11_RS07615	COG0583	DNA-binding transcription factor activity
LLUC11_RS07620	COG0371	Dehydrogenase
LLUC11_RS07630	COG4690	dipeptidase activity
LLUC11_RS07635	COG0617	tRNA 3'-terminal CCA addition
LLUC11_RS07645	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
LLUC11_RS07650	COG1307	EDD domain protein, DegV family
LLUC11_RS07660	COG0336	Belongs to the RNA methyltransferase TrmD family
LLUC11_RS07665	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LLUC11_RS07670	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LLUC11_RS07695	COG1837	Belongs to the UPF0109 family
LLUC11_RS07700	COG0228	four-way junction DNA binding
LLUC11_RS07710	COG0183	Belongs to the thiolase family
LLUC11_RS07715	COG3425	synthase
LLUC11_RS07720	COG0363	glucosamine-6-phosphate deaminase activity
LLUC11_RS07735	COG3942	CHAP domain
LLUC11_RS07765	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LLUC11_RS07820	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LLUC11_RS07830	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LLUC11_RS07835	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LLUC11_RS07840	COG0347	Belongs to the P(II) protein family
LLUC11_RS07845	COG0004	ammonium transporteR
LLUC11_RS07850	COG5002	protein histidine kinase activity
LLUC11_RS07855	COG0745	RESPONSE REGULATOR receiver
LLUC11_RS07860	COG1399	metal-binding, possibly nucleic acid-binding protein
LLUC11_RS07865	COG0254	rRNA binding
LLUC11_RS07880	COG3942	CHAP domain
LLUC11_RS07880	COG1705	Flagellar rod assembly protein muramidase FlgJ
LLUC11_RS07885	COG1408	metallophosphoesterase
LLUC11_RS07925	COG0589	response to stress
LLUC11_RS07940	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LLUC11_RS08000	COG0582	viral genome integration into host DNA
LLUC11_RS08005	COG0505	Belongs to the CarA family
LLUC11_RS08010	COG0540	Belongs to the ATCase OTCase family
LLUC11_RS08020	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LLUC11_RS08035	COG1230	cation diffusion facilitator family transporter
LLUC11_RS08040	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LLUC11_RS08045	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LLUC11_RS08075	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LLUC11_RS08080	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LLUC11_RS08095	COG1285	pathogenesis
LLUC11_RS08100	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LLUC11_RS08110	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LLUC11_RS08140	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LLUC11_RS08145	COG0800	Aldolase
LLUC11_RS08150	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LLUC11_RS08155	COG1904	glucuronate isomerase
LLUC11_RS08170	COG1312	Catalyzes the dehydration of D-mannonate
LLUC11_RS08175	COG0246	Mannitol dehydrogenase
LLUC11_RS08180	COG1802	Transcriptional regulator
LLUC11_RS08185	COG0477	Major facilitator Superfamily
LLUC11_RS08245	COG0582	viral genome integration into host DNA
LLUC11_RS08250	COG1879	ABC-type sugar transport system periplasmic component
LLUC11_RS08255	COG1172	Belongs to the binding-protein-dependent transport system permease family
LLUC11_RS08260	COG1129	ABC transporter
LLUC11_RS08265	COG1869	D-ribose catabolic process
LLUC11_RS08270	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LLUC11_RS08275	COG1609	Transcriptional regulator
LLUC11_RS08280	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LLUC11_RS08285	COG0710	3-dehydroquinate dehydratase activity
LLUC11_RS08300	COG3118	belongs to the thioredoxin family
LLUC11_RS08305	COG1193	negative regulation of DNA recombination
LLUC11_RS08315	COG0492	ferredoxin-NADP+ reductase activity
LLUC11_RS08320	COG1609	Transcriptional regulator
LLUC11_RS08325	COG0006	proline dipeptidase activity
LLUC11_RS08335	COG0116	Belongs to the methyltransferase superfamily
LLUC11_RS08345	COG3599	regulation of cell shape
LLUC11_RS08350	COG1466	dna polymerase III delta subunit
LLUC11_RS08360	COG1674	ftsk spoiiie
LLUC11_RS08365	COG0561	phosphatase activity
LLUC11_RS08375	COG0280	phosphate acetyltransferase
LLUC11_RS08380	COG0572	uridine kinase
LLUC11_RS08385	COG0673	inositol 2-dehydrogenase activity
LLUC11_RS08395	COG0741	lytic transglycosylase activity
LLUC11_RS08440	COG2723	6-phospho-beta-galactosidase activity
LLUC11_RS08445	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
LLUC11_RS08450	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LLUC11_RS08455	COG5002	protein histidine kinase activity
LLUC11_RS08460	COG0745	RESPONSE REGULATOR receiver
LLUC11_RS08465	COG1609	Transcriptional regulator
LLUC11_RS08475	COG0366	Alpha amylase catalytic
LLUC11_RS08480	COG0366	Alpha amylase catalytic
LLUC11_RS08485	COG0110	maltose O-acetyltransferase activity
LLUC11_RS08490	COG0366	Alpha amylase catalytic
LLUC11_RS08495	COG0366	Alpha amylase catalytic
LLUC11_RS08505	COG1175	transmembrane transport
LLUC11_RS08510	COG3833	ABC-type maltose transport systems, permease component
LLUC11_RS08535	COG3655	Transcriptional regulator
LLUC11_RS08575	COG0640	Transcriptional regulator
LLUC11_RS08580	COG1902	pentaerythritol trinitrate reductase activity
LLUC11_RS08615	COG2957	Belongs to the agmatine deiminase family
LLUC11_RS08620	COG0531	amino acid
LLUC11_RS08625	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LLUC11_RS08630	COG2197	response regulator
LLUC11_RS08640	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
LLUC11_RS08660	COG3715	PTS system
LLUC11_RS08665	COG3716	PTS system mannose fructose sorbose family IID component
LLUC11_RS08685	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LLUC11_RS08690	COG1619	proteins homologs of microcin C7 resistance protein MccF
LLUC11_RS08700	COG0704	Plays a role in the regulation of phosphate uptake
LLUC11_RS08705	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LLUC11_RS08710	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LLUC11_RS08715	COG0581	inorganic phosphate transmembrane transporter activity
LLUC11_RS08720	COG0573	inorganic phosphate transmembrane transporter activity
LLUC11_RS08735	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LLUC11_RS08745	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LLUC11_RS08750	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LLUC11_RS08755	COG4122	O-methyltransferase activity
LLUC11_RS08760	COG1164	Oligoendopeptidase f
LLUC11_RS08780	COG2252	PERMEase
LLUC11_RS08785	COG0561	phosphatase activity
LLUC11_RS08790	COG0247	lactate metabolic process
LLUC11_RS08795	COG1139	Iron-sulfur cluster binding protein
LLUC11_RS08800	COG1556	Lactate utilization protein
LLUC11_RS08805	COG0670	Belongs to the BI1 family
LLUC11_RS08820	COG0268	Binds directly to 16S ribosomal RNA
LLUC11_RS08825	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LLUC11_RS08830	COG0406	alpha-ribazole phosphatase activity
LLUC11_RS08835	COG0077	Prephenate dehydratase
LLUC11_RS08840	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LLUC11_RS08845	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LLUC11_RS08850	COG0287	Prephenate dehydrogenase
LLUC11_RS08855	COG5002	protein histidine kinase activity
LLUC11_RS08860	COG0745	RESPONSE REGULATOR receiver
LLUC11_RS08870	COG0577	efflux transmembrane transporter activity
LLUC11_RS08875	COG1136	(ABC) transporter
LLUC11_RS08885	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LLUC11_RS08895	COG4493	Belongs to the UPF0637 family
LLUC11_RS08905	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LLUC11_RS08910	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LLUC11_RS08920	COG0765	amino acid transport
LLUC11_RS08925	COG1126	abc transporter atp-binding protein
LLUC11_RS08940	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LLUC11_RS08945	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LLUC11_RS08950	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LLUC11_RS08955	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LLUC11_RS08960	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LLUC11_RS08965	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LLUC11_RS08970	COG0356	it plays a direct role in the translocation of protons across the membrane
LLUC11_RS08985	COG0658	competence protein
LLUC11_RS08985	COG2333	competence protein COMEC
LLUC11_RS09000	COG4152	abc transporter atp-binding protein
LLUC11_RS09020	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LLUC11_RS09030	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
LLUC11_RS09030	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
LLUC11_RS09035	COG1268	BioY protein
LLUC11_RS09040	COG0318	PFAM AMP-dependent synthetase and ligase
LLUC11_RS09045	COG0183	Belongs to the thiolase family
LLUC11_RS09060	COG1028	Short-chain dehydrogenase reductase Sdr
LLUC11_RS09070	COG0719	Fe-S assembly protein
LLUC11_RS09085	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LLUC11_RS09090	COG0719	Fe-S assembly protein
LLUC11_RS09100	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LLUC11_RS09105	COG4862	establishment of competence for transformation
LLUC11_RS09110	COG1126	abc transporter atp-binding protein
LLUC11_RS09115	COG0765	amino acid transport
LLUC11_RS09125	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LLUC11_RS09130	COG0085	RNA polymerase activity
LLUC11_RS09140	COG1396	sequence-specific DNA binding
LLUC11_RS09145	COG3590	peptidase
LLUC11_RS09155	COG2244	polysaccharide biosynthetic process
LLUC11_RS09160	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LLUC11_RS09170	COG1064	alcohol dehydrogenase
LLUC11_RS09175	COG0514	ATP-dependent DNA helicase (RecQ)
LLUC11_RS09195	COG1227	inorganic diphosphatase activity
LLUC11_RS09200	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LLUC11_RS09205	COG1253	flavin adenine dinucleotide binding
LLUC11_RS09210	COG0628	permease
LLUC11_RS09245	COG3409	Peptidoglycan-binding domain 1 protein
LLUC11_RS09265	COG1573	uracil-dna glycosylase
LLUC11_RS09270	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LLUC11_RS09280	COG2062	phosphohistidine phosphatase, SixA
LLUC11_RS09285	COG2827	Endonuclease containing a URI domain
LLUC11_RS09290	COG1113	amino acid transport
LLUC11_RS09300	COG1564	THIamine pyrophosphokinase
LLUC11_RS09320	COG0017	Asparaginyl-tRNA synthetase
LLUC11_RS09330	COG0436	Aminotransferase
LLUC11_RS09340	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LLUC11_RS09340	COG1199	ATP-dependent helicase activity
LLUC11_RS09350	COG1253	flavin adenine dinucleotide binding
LLUC11_RS09360	COG2365	Tyrosine phosphatase family
LLUC11_RS09365	COG0747	negative chemotaxis
LLUC11_RS09370	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LLUC11_RS09375	COG0601	transmembrane transport
LLUC11_RS09380	COG4608	Belongs to the ABC transporter superfamily
LLUC11_RS09385	COG0444	Belongs to the ABC transporter superfamily
LLUC11_RS09390	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LLUC11_RS09395	COG0291	Belongs to the bacterial ribosomal protein bL35 family
LLUC11_RS09400	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LLUC11_RS09415	COG0445	tRNA wobble uridine modification
LLUC11_RS09430	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
LLUC11_RS09435	COG0215	cysteine-tRNA ligase activity
LLUC11_RS09445	COG1045	serine acetyltransferase
LLUC11_RS09455	COG1185	polyribonucleotide nucleotidyltransferase activity
LLUC11_RS09465	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LLUC11_RS09470	COG0589	response to stress
LLUC11_RS09475	COG1104	cysteine desulfurase activity
LLUC11_RS09485	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LLUC11_RS09500	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LLUC11_RS09505	COG3599	regulation of cell shape
LLUC11_RS09520	COG1799	cell septum assembly
LLUC11_RS09525	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LLUC11_RS09530	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LLUC11_RS09535	COG0849	cell division
LLUC11_RS09540	COG1307	EDD domain protein, DegV family
LLUC11_RS09550	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LLUC11_RS09555	COG0656	L-ascorbic acid biosynthetic process
LLUC11_RS09565	COG0583	DNA-binding transcription factor activity
LLUC11_RS09575	COG3579	cysteine-type endopeptidase activity
LLUC11_RS09585	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LLUC11_RS09595	COG0494	nUDIX hydrolase
LLUC11_RS09600	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LLUC11_RS09605	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LLUC11_RS09610	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LLUC11_RS09615	COG2815	serine threonine protein kinase
LLUC11_RS09615	COG0515	serine threonine protein kinase
LLUC11_RS09620	COG0631	protein serine/threonine phosphatase activity
LLUC11_RS09625	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LLUC11_RS09625	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LLUC11_RS09645	COG2261	transglycosylase associated protein
LLUC11_RS09655	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LLUC11_RS09675	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LLUC11_RS09680	COG1758	RNA polymerase activity
LLUC11_RS09685	COG0194	GDP metabolic process
LLUC11_RS09690	COG1418	mRNA catabolic process
LLUC11_RS09695	COG0363	glucosamine-6-phosphate deaminase activity
LLUC11_RS09700	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LLUC11_RS09705	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LLUC11_RS09710	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LLUC11_RS09715	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LLUC11_RS09720	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
LLUC11_RS09720	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
LLUC11_RS09725	COG1983	PspC domain protein
LLUC11_RS09750	COG0191	fructose-bisphosphate aldolase activity
LLUC11_RS09810	COG2860	membrane
LLUC11_RS09815	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LLUC11_RS09835	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LLUC11_RS09845	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
LLUC11_RS09850	COG0626	cystathionine gamma-synthase activity
LLUC11_RS09855	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
LLUC11_RS09875	COG3481	metal-dependent phosphohydrolase, HD sub domain
LLUC11_RS09885	COG1660	Displays ATPase and GTPase activities
LLUC11_RS09905	COG1162	GTPase activity
LLUC11_RS09910	COG1388	LysM domain
LLUC11_RS09910	COG3584	3D domain protein
LLUC11_RS09915	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LLUC11_RS09915	COG0072	phenylalanine-tRNA ligase activity
LLUC11_RS09925	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LLUC11_RS09930	COG3479	Phenolic acid decarboxylase
LLUC11_RS09940	COG3469	chitinase activity
LLUC11_RS09950	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LLUC11_RS09990	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LLUC11_RS09995	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LLUC11_RS10000	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LLUC11_RS10010	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LLUC11_RS10015	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LLUC11_RS10020	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LLUC11_RS10025	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LLUC11_RS10030	COG0537	adenosine 5'-monophosphoramidase activity
LLUC11_RS10035	COG0124	histidyl-tRNA synthetase
LLUC11_RS10045	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LLUC11_RS10050	COG1426	Protein conserved in bacteria
LLUC11_RS10055	COG0612	Peptidase, M16
LLUC11_RS10060	COG0612	Peptidase, M16
LLUC11_RS10065	COG2501	S4 domain
LLUC11_RS10070	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LLUC11_RS10075	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LLUC11_RS10080	COG4978	Transcriptional regulator
LLUC11_RS10080	COG0789	Transcriptional regulator
LLUC11_RS10090	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LLUC11_RS10095	COG3250	beta-galactosidase activity
LLUC11_RS10100	COG0110	maltose O-acetyltransferase activity
LLUC11_RS10105	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
LLUC11_RS10110	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LLUC11_RS10130	COG0667	Aldo Keto reductase
LLUC11_RS10145	COG0826	peptidase U32
LLUC11_RS10165	COG0500	methyltransferase
LLUC11_RS10180	COG1131	(ABC) transporter
LLUC11_RS10185	COG0584	glycerophosphoryl diester phosphodiesterase
LLUC11_RS10190	COG0537	adenosine 5'-monophosphoramidase activity
LLUC11_RS10205	COG0081	regulation of translation
LLUC11_RS10210	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LLUC11_RS10220	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LLUC11_RS10225	COG4479	Belongs to the UPF0346 family
LLUC11_RS10230	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LLUC11_RS10235	COG2996	Protein conserved in bacteria
LLUC11_RS10245	COG0233	cytoplasmic translational termination
LLUC11_RS10260	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LLUC11_RS10265	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LLUC11_RS10270	COG0827	DNA restriction-modification system
LLUC11_RS10280	COG1217	gtp-binding protein TYPA
LLUC11_RS10295	COG0577	efflux transmembrane transporter activity
LLUC11_RS10295	COG1136	(ABC) transporter
LLUC11_RS10320	COG1940	carbohydrate kinase activity
LLUC11_RS10330	COG0783	Belongs to the Dps family
LLUC11_RS10340	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LLUC11_RS10350	COG0531	amino acid
LLUC11_RS10355	COG0436	Aminotransferase
LLUC11_RS10370	COG0531	amino acid
LLUC11_RS10375	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LLUC11_RS10380	COG2235	arginine
LLUC11_RS10390	COG0018	arginyl-trna synthetase
LLUC11_RS10400	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LLUC11_RS10410	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LLUC11_RS10425	COG0028	Belongs to the TPP enzyme family
LLUC11_RS10430	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LLUC11_RS10440	COG1266	CAAX protease self-immunity
LLUC11_RS10445	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LLUC11_RS10450	COG2936	dipeptidyl-peptidase activity
LLUC11_RS10455	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
LLUC11_RS10460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LLUC11_RS10465	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LLUC11_RS10470	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LLUC11_RS10510	COG4956	integral membrane protein (PIN domain superfamily)
LLUC11_RS10530	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
LLUC11_RS10535	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
LLUC11_RS10545	COG0203	ribosomal protein L17
LLUC11_RS10550	COG0202	RNA polymerase activity
LLUC11_RS10555	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LLUC11_RS10560	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LLUC11_RS10565	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LLUC11_RS10570	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LLUC11_RS10575	COG0563	adenylate kinase activity
LLUC11_RS10580	COG0201	protein transport
LLUC11_RS10585	COG0200	Binds to the 23S rRNA
LLUC11_RS10590	COG1841	ribosomal large subunit assembly
LLUC11_RS10595	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LLUC11_RS10600	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LLUC11_RS10605	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LLUC11_RS10610	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LLUC11_RS10620	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LLUC11_RS10625	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LLUC11_RS10630	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LLUC11_RS10635	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LLUC11_RS10640	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LLUC11_RS10645	COG0255	Belongs to the universal ribosomal protein uL29 family
LLUC11_RS10650	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LLUC11_RS10655	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LLUC11_RS10660	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LLUC11_RS10665	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LLUC11_RS10670	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LLUC11_RS10680	COG0088	Forms part of the polypeptide exit tunnel
LLUC11_RS10685	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LLUC11_RS10690	COG0051	transcription antitermination factor activity, RNA binding
LLUC11_RS10695	COG1970	mechanosensitive ion channel activity
LLUC11_RS10705	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LLUC11_RS10710	COG0250	Participates in transcription elongation, termination and antitermination
LLUC11_RS10720	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LLUC11_RS10725	COG2755	lipolytic protein G-D-S-L family
LLUC11_RS10725	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
LLUC11_RS10730	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LLUC11_RS10735	COG2323	membrane
LLUC11_RS10750	COG0564	pseudouridine synthase activity
LLUC11_RS10755	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LLUC11_RS10760	COG1121	(ABC) transporter
LLUC11_RS10765	COG3443	Belongs to the bacterial solute-binding protein 9 family
LLUC11_RS10765	COG0803	Belongs to the bacterial solute-binding protein 9 family
LLUC11_RS10770	COG1846	Transcriptional regulator
LLUC11_RS10795	COG4537	Required for transformation and DNA binding
LLUC11_RS10800	COG1459	type II secretion system
LLUC11_RS10805	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LLUC11_RS10810	COG2176	DNA-directed DNA polymerase activity
LLUC11_RS10820	COG0446	pyridine nucleotide-disulphide oxidoreductase
LLUC11_RS10825	COG0442	prolyl-tRNA aminoacylation
LLUC11_RS10830	COG0750	zinc metalloprotease
LLUC11_RS10835	COG4589	Belongs to the CDS family
LLUC11_RS10840	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LLUC11_RS10845	COG1862	Preprotein translocase
LLUC11_RS10855	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LLUC11_RS10860	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LLUC11_RS10870	COG0438	transferase activity, transferring glycosyl groups
LLUC11_RS10885	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
LLUC11_RS10890	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LLUC11_RS10890	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LLUC11_RS10895	COG0561	phosphatase activity
LLUC11_RS10900	COG1609	Transcriptional regulator
LLUC11_RS10930	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
LLUC11_RS10935	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LLUC11_RS10940	COG0052	Belongs to the universal ribosomal protein uS2 family
LLUC11_RS10945	COG2706	6-phosphogluconolactonase activity
LLUC11_RS10950	COG1454	alcohol dehydrogenase
LLUC11_RS10950	COG1012	belongs to the aldehyde dehydrogenase family
LLUC11_RS10955	COG1396	sequence-specific DNA binding
LLUC11_RS10965	COG0535	radical SAM domain protein
LLUC11_RS10975	COG3480	Lon protease (S16) C-terminal proteolytic domain
LLUC11_RS10980	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LLUC11_RS10985	COG0742	ribosomal rna small subunit methyltransferase
LLUC11_RS10990	COG2814	Major facilitator Superfamily
LLUC11_RS11000	COG0166	Belongs to the GPI family
LLUC11_RS11015	COG1733	regulation of RNA biosynthetic process
LLUC11_RS11025	COG0525	valine-tRNA ligase activity
LLUC11_RS11055	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LLUC11_RS11070	COG2137	regulation of response to DNA damage stimulus
LLUC11_RS11100	COG1070	Carbohydrate kinase
LLUC11_RS11105	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
LLUC11_RS11120	COG1408	metallophosphoesterase
LLUC11_RS11125	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LLUC11_RS11130	COG0629	single-stranded DNA binding
LLUC11_RS11135	COG0360	Binds together with S18 to 16S ribosomal RNA
LLUC11_RS11140	COG1968	undecaprenyl-diphosphatase activity
LLUC11_RS11145	COG0833	amino acid
LLUC11_RS11150	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LLUC11_RS11160	COG1956	GAF domain-containing protein
LLUC11_RS11175	COG4974	Belongs to the 'phage' integrase family
LLUC11_RS11300	COG0174	glutamine synthetase
LLUC11_RS11305	COG0789	Transcriptional regulator
LLUC11_RS11310	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LLUC11_RS11315	COG1131	(ABC) transporter
LLUC11_RS11335	COG2255	four-way junction helicase activity
LLUC11_RS11340	COG0632	four-way junction helicase activity
LLUC11_RS11345	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LLUC11_RS11355	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LLUC11_RS11365	COG2084	Dehydrogenase
LLUC11_RS11385	COG0730	response to heat
LLUC11_RS11395	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LLUC11_RS11400	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
LLUC11_RS11405	COG0484	heat shock protein binding
LLUC11_RS11425	COG0367	asparagine synthase
LLUC11_RS11430	COG3942	CHAP domain
LLUC11_RS11430	COG3883	PFAM NLP P60 protein
LLUC11_RS11445	COG0494	nUDIX hydrolase
LLUC11_RS11450	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LLUC11_RS11455	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LLUC11_RS11460	COG2814	Major facilitator Superfamily
LLUC11_RS11465	COG0589	response to stress
LLUC11_RS11480	COG1309	transcriptional regulator
LLUC11_RS11485	COG1187	pseudouridine synthase activity
LLUC11_RS11495	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LLUC11_RS11505	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LLUC11_RS11510	COG2824	Alkylphosphonate utilization operon protein PhnA
LLUC11_RS11530	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LLUC11_RS11545	COG1266	CAAX protease self-immunity
LLUC11_RS11560	COG0494	nUDIX hydrolase
LLUC11_RS11645	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LLUC11_RS11650	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LLUC11_RS11660	COG1136	(ABC) transporter
LLUC11_RS11665	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LLUC11_RS11670	COG0681	Belongs to the peptidase S26 family
LLUC11_RS11675	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LLUC11_RS11680	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LLUC11_RS11685	COG0049	tRNA binding
LLUC11_RS11690	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LLUC11_RS11695	COG1686	Belongs to the peptidase S11 family
LLUC11_RS11700	COG4975	Glucose uptake
LLUC11_RS11705	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
LLUC11_RS11710	COG1242	4 iron, 4 sulfur cluster binding
LLUC11_RS11755	COG1192	Involved in chromosome partitioning
LLUC11_RS11770	COG3201	nicotinamide mononucleotide transporter
LLUC11_RS11795	COG0390	transport system, permease component
LLUC11_RS11800	COG4619	ABC transporter
LLUC11_RS11815	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LLUC11_RS11820	COG0569	domain protein
LLUC11_RS11850	COG3843	relaxase mobilization nuclease domain protein
LLUC11_RS11890	COG2261	transglycosylase associated protein
LLUC11_RS11925	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LLUC11_RS11935	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LLUC11_RS11945	COG1780	Probably involved in ribonucleotide reductase function
LLUC11_RS11950	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LLUC11_RS11965	COG3976	FMN-binding domain protein
LLUC11_RS11965	COG0431	NADPH-dependent FMN reductase
LLUC11_RS11965	COG1053	succinate dehydrogenase
LLUC11_RS11970	COG0431	NADPH-dependent FMN reductase
LLUC11_RS11970	COG1053	succinate dehydrogenase
LLUC11_RS11970	COG3976	FMN-binding domain protein
LLUC11_RS12005	COG3590	peptidase
LLUC11_RS12015	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LLUC11_RS12020	COG0601	transmembrane transport
LLUC11_RS12025	COG4608	Belongs to the ABC transporter superfamily
LLUC11_RS12030	COG0444	Belongs to the ABC transporter superfamily
LLUC11_RS12045	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LLUC11_RS12130	COG0629	single-stranded DNA binding
LLUC11_RS12135	COG3942	CHAP domain
LLUC11_RS12135	COG1705	Flagellar rod assembly protein muramidase FlgJ
LLUC11_RS12180	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LLUC11_RS12180	COG0551	DNA topoisomerase type I activity
LLUC11_RS12215	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LLUC11_RS12245	COG0640	Transcriptional regulator
LLUC11_RS12260	COG2801	Transposase and inactivated derivatives
LLUC11_RS12265	COG4619	ABC transporter
LLUC11_RS12270	COG0390	transport system, permease component
LLUC11_RS12275	COG0662	Cupin 2, conserved barrel domain protein
LLUC11_RS12335	COG2207	Transcriptional regulator
LLUC11_RS12335	COG3708	Transcriptional regulator
LLUC11_RS12400	COG2184	nucleotidyltransferase activity