locus-tag	class	description
BHS01_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BHS01_RS00010	COG1475	DNA binding
BHS01_RS00015	COG2261	transglycosylase associated protein
BHS01_RS00020	COG1054	Belongs to the UPF0176 family
BHS01_RS00025	COG0519	Catalyzes the synthesis of GMP from XMP
BHS01_RS00035	COG1862	Preprotein translocase
BHS01_RS00040	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BHS01_RS00045	COG4589	Belongs to the CDS family
BHS01_RS00050	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BHS01_RS00055	COG0750	zinc metalloprotease
BHS01_RS00060	COG0442	prolyl-tRNA aminoacylation
BHS01_RS00105	COG1396	sequence-specific DNA binding
BHS01_RS00110	COG2189	Belongs to the N(4) N(6)-methyltransferase family
BHS01_RS00115	COG3421	Type III restriction
BHS01_RS00160	COG1131	(ABC) transporter
BHS01_RS00175	COG0697	spore germination
BHS01_RS00190	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BHS01_RS00195	COG1846	Transcriptional regulator
BHS01_RS00200	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BHS01_RS00210	COG0436	Aminotransferase
BHS01_RS00220	COG0584	glycerophosphoryl diester phosphodiesterase
BHS01_RS00225	COG1418	mRNA catabolic process
BHS01_RS00235	COG0488	(ABC) transporter
BHS01_RS00240	COG0561	phosphatase activity
BHS01_RS00270	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BHS01_RS00275	COG4974	Belongs to the 'phage' integrase family
BHS01_RS00340	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BHS01_RS00350	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BHS01_RS00375	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BHS01_RS00380	COG4608	Belongs to the ABC transporter superfamily
BHS01_RS00385	COG0444	Belongs to the ABC transporter superfamily
BHS01_RS00390	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BHS01_RS00395	COG0601	transmembrane transport
BHS01_RS00405	COG1216	Glycosyl transferase, family 2
BHS01_RS00405	COG1442	glycosyl transferase family 8
BHS01_RS00435	COG1705	Flagellar rod assembly protein muramidase FlgJ
BHS01_RS00435	COG1388	LysM domain
BHS01_RS00460	COG0517	IMP dehydrogenase activity
BHS01_RS00465	COG0204	Acyl-transferase
BHS01_RS00470	COG1725	Transcriptional regulator
BHS01_RS00475	COG1131	(ABC) transporter
BHS01_RS00495	COG2910	NAD(P)H-binding
BHS01_RS00505	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BHS01_RS00510	COG1534	Rna-binding protein
BHS01_RS00515	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BHS01_RS00520	COG1713	HD superfamily hydrolase involved in NAD metabolism
BHS01_RS00525	COG0799	negative regulation of ribosome biogenesis
BHS01_RS00530	COG2226	methyltransferase
BHS01_RS00545	COG0217	transcriptional regulatory protein
BHS01_RS00550	COG0456	acetyltransferase
BHS01_RS00555	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BHS01_RS00570	COG1854	S-ribosylhomocysteine lyase activity
BHS01_RS00675	COG1131	(ABC) transporter
BHS01_RS00680	COG0842	Transport permease protein
BHS01_RS00700	COG0656	L-ascorbic acid biosynthetic process
BHS01_RS00715	COG0542	response to heat
BHS01_RS00725	COG1131	(ABC) transporter
BHS01_RS00735	COG1328	CTP reductase activity
BHS01_RS00750	COG1122	ATPase activity
BHS01_RS00755	COG1122	ATPase activity
BHS01_RS00760	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BHS01_RS00770	COG1473	amidohydrolase
BHS01_RS00775	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BHS01_RS00780	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BHS01_RS00780	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BHS01_RS00785	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BHS01_RS00790	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BHS01_RS00795	COG3715	PTS system
BHS01_RS00800	COG3716	PTS system mannose fructose sorbose family IID component
BHS01_RS00815	COG1464	Belongs to the NlpA lipoprotein family
BHS01_RS00820	COG0534	Mate efflux family protein
BHS01_RS00830	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BHS01_RS00840	COG1447	Phosphotransferase system cellobiose-specific component IIA
BHS01_RS00845	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BHS01_RS00850	COG2723	6-phospho-beta-galactosidase activity
BHS01_RS00855	COG0737	Belongs to the 5'-nucleotidase family
BHS01_RS00860	COG4470	Protein conserved in bacteria
BHS01_RS00880	COG1832	CoA-binding protein
BHS01_RS00950	COG1349	DNA-binding transcription factor activity
BHS01_RS00980	COG3623	hexulose-6-phosphate isomerase
BHS01_RS01010	COG1874	Beta-galactosidase
BHS01_RS01020	COG2017	converts alpha-aldose to the beta-anomer
BHS01_RS01025	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BHS01_RS01030	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
BHS01_RS01035	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BHS01_RS01040	COG2176	DNA-directed DNA polymerase activity
BHS01_RS01045	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BHS01_RS01050	COG1459	type II secretion system
BHS01_RS01085	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BHS01_RS01090	COG1846	Transcriptional regulator
BHS01_RS01095	COG1121	(ABC) transporter
BHS01_RS01100	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BHS01_RS01110	COG3759	membrane
BHS01_RS01115	COG0778	Nitroreductase
BHS01_RS01125	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BHS01_RS01130	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BHS01_RS01140	COG0250	Participates in transcription elongation, termination and antitermination
BHS01_RS01155	COG0051	transcription antitermination factor activity, RNA binding
BHS01_RS01175	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BHS01_RS01180	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BHS01_RS01185	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BHS01_RS01190	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BHS01_RS01200	COG0255	Belongs to the universal ribosomal protein uL29 family
BHS01_RS01210	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BHS01_RS01215	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BHS01_RS01220	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BHS01_RS01225	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BHS01_RS01230	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BHS01_RS01235	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BHS01_RS01245	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BHS01_RS01250	COG1841	ribosomal large subunit assembly
BHS01_RS01255	COG0200	Binds to the 23S rRNA
BHS01_RS01260	COG0201	protein transport
BHS01_RS01265	COG0563	adenylate kinase activity
BHS01_RS01270	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BHS01_RS01275	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BHS01_RS01280	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BHS01_RS01290	COG0202	RNA polymerase activity
BHS01_RS01295	COG0203	ribosomal protein L17
BHS01_RS01305	COG2918	glutathione biosynthetic process
BHS01_RS01305	COG1181	Belongs to the D-alanine--D-alanine ligase family
BHS01_RS01310	COG0129	dihydroxy-acid dehydratase activity
BHS01_RS01315	COG0463	Glycosyl transferase, family 2
BHS01_RS01320	COG0028	Belongs to the TPP enzyme family
BHS01_RS01325	COG0440	acetolactate synthase activity
BHS01_RS01330	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BHS01_RS01335	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BHS01_RS01400	COG2824	Alkylphosphonate utilization operon protein PhnA
BHS01_RS01405	COG3679	Belongs to the UPF0342 family
BHS01_RS01420	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BHS01_RS01425	COG0300	oxidoreductase activity
BHS01_RS01430	COG3104	oligopeptide transport
BHS01_RS01445	COG0431	NADPH-dependent FMN reductase
BHS01_RS01450	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BHS01_RS01455	COG0431	NADPH-dependent FMN reductase
BHS01_RS01480	COG2884	Cell division ATP-binding protein ftsE
BHS01_RS01485	COG1307	EDD domain protein, DegV family
BHS01_RS01495	COG0137	argininosuccinate synthase activity
BHS01_RS01500	COG0165	Argininosuccinate lyase
BHS01_RS01505	COG0594	ribonuclease P activity
BHS01_RS01510	COG0706	membrane insertase activity
BHS01_RS01520	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BHS01_RS01525	COG4989	oxidoreductase activity
BHS01_RS01530	COG4472	Bacterial protein of unknown function (DUF965)
BHS01_RS01535	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BHS01_RS01540	COG3906	Belongs to the UPF0473 family
BHS01_RS01545	COG0436	Aminotransferase
BHS01_RS01555	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BHS01_RS01560	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BHS01_RS01565	COG0154	amidase activity
BHS01_RS01570	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BHS01_RS01585	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BHS01_RS01585	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BHS01_RS01610	COG0446	pyridine nucleotide-disulphide oxidoreductase
BHS01_RS01630	COG2249	NAD(P)H dehydrogenase (quinone) activity
BHS01_RS01655	COG1438	arginine binding
BHS01_RS01665	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BHS01_RS01720	COG0789	Transcriptional regulator
BHS01_RS01725	COG0174	glutamine synthetase
BHS01_RS01735	COG0038	chloride channel
BHS01_RS01750	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BHS01_RS01795	COG1126	abc transporter atp-binding protein
BHS01_RS01800	COG0765	amino acid transport
BHS01_RS01805	COG1968	undecaprenyl-diphosphatase activity
BHS01_RS01810	COG2814	Major facilitator Superfamily
BHS01_RS01820	COG0583	DNA-binding transcription factor activity
BHS01_RS01850	COG1461	Dihydroxyacetone kinase
BHS01_RS01865	COG2190	(PTS) system
BHS01_RS01865	COG2211	Major facilitator Superfamily
BHS01_RS01880	COG0360	Binds together with S18 to 16S ribosomal RNA
BHS01_RS01885	COG0629	single-stranded DNA binding
BHS01_RS01890	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BHS01_RS01900	COG1187	pseudouridine synthase activity
BHS01_RS01905	COG2137	regulation of response to DNA damage stimulus
BHS01_RS01910	COG4978	Transcriptional regulator
BHS01_RS01910	COG0789	Transcriptional regulator
BHS01_RS01915	COG2217	Heavy metal translocating P-type atpase
BHS01_RS01920	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BHS01_RS01940	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BHS01_RS01940	COG3711	transcriptional antiterminator
BHS01_RS01945	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BHS01_RS01945	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BHS01_RS01945	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BHS01_RS01955	COG2855	membrane
BHS01_RS01960	COG0583	DNA-binding transcription factor activity
BHS01_RS01965	COG2040	homocysteine
BHS01_RS01970	COG0833	amino acid
BHS01_RS02035	COG0582	viral genome integration into host DNA
BHS01_RS02040	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BHS01_RS02050	COG1129	ABC transporter
BHS01_RS02085	COG1175	transmembrane transport
BHS01_RS02090	COG0395	ABC-type sugar transport system, permease component
BHS01_RS02105	COG3940	Belongs to the glycosyl hydrolase 43 family
BHS01_RS02120	COG2160	L-arabinose isomerase activity
BHS01_RS02125	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BHS01_RS02130	COG0346	lactoylglutathione lyase activity
BHS01_RS02135	COG0400	carboxylic ester hydrolase activity
BHS01_RS02165	COG1132	(ABC) transporter
BHS01_RS02170	COG0756	dUTP diphosphatase activity
BHS01_RS02185	COG4956	integral membrane protein (PIN domain superfamily)
BHS01_RS02190	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BHS01_RS02195	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BHS01_RS02200	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BHS01_RS02210	COG2936	dipeptidyl-peptidase activity
BHS01_RS02215	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BHS01_RS02220	COG1266	CAAX protease self-immunity
BHS01_RS02255	COG0827	DNA restriction-modification system
BHS01_RS02260	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BHS01_RS02265	COG0528	UMP kinase activity
BHS01_RS02270	COG0233	cytoplasmic translational termination
BHS01_RS02275	COG2996	Protein conserved in bacteria
BHS01_RS02280	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BHS01_RS02285	COG4479	Belongs to the UPF0346 family
BHS01_RS02295	COG4842	Belongs to the WXG100 family
BHS01_RS02310	COG4499	WXG100 protein secretion system (Wss), protein YukC
BHS01_RS02315	COG1674	ftsk spoiiie
BHS01_RS02315	COG1674	ftsk spoiiie
BHS01_RS02340	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BHS01_RS02350	COG0716	FMN binding
BHS01_RS02370	COG4708	membrane
BHS01_RS02375	COG0386	Belongs to the glutathione peroxidase family
BHS01_RS02390	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BHS01_RS02390	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BHS01_RS02395	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BHS01_RS02400	COG1418	mRNA catabolic process
BHS01_RS02405	COG0194	GDP metabolic process
BHS01_RS02415	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BHS01_RS02425	COG3688	RNA-binding protein containing a PIN domain
BHS01_RS02430	COG1307	EDD domain protein, DegV family
BHS01_RS02440	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BHS01_RS02445	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BHS01_RS02450	COG1799	cell septum assembly
BHS01_RS02465	COG3599	regulation of cell shape
BHS01_RS02470	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BHS01_RS02485	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BHS01_RS02490	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BHS01_RS02510	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BHS01_RS02515	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BHS01_RS02535	COG1234	tRNA 3'-trailer cleavage
BHS01_RS02540	COG0300	oxidoreductase activity
BHS01_RS02545	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BHS01_RS02545	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BHS01_RS02550	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BHS01_RS02555	COG3343	RNA polymerase activity
BHS01_RS02560	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BHS01_RS02565	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BHS01_RS02570	COG4463	regulation of RNA biosynthetic process
BHS01_RS02575	COG0542	response to heat
BHS01_RS02580	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BHS01_RS02590	COG0252	asparaginase activity
BHS01_RS02605	COG1882	Formate acetyltransferase
BHS01_RS02615	COG0237	dephospho-CoA kinase activity
BHS01_RS02620	COG2814	Major facilitator Superfamily
BHS01_RS02630	COG0772	Belongs to the SEDS family
BHS01_RS02635	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BHS01_RS02640	COG0191	fructose-bisphosphate aldolase activity
BHS01_RS02650	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BHS01_RS02655	COG5002	protein histidine kinase activity
BHS01_RS02660	COG0745	RESPONSE REGULATOR receiver
BHS01_RS02665	COG1126	abc transporter atp-binding protein
BHS01_RS02670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BHS01_RS02675	COG0765	amino acid transport
BHS01_RS02680	COG0765	amino acid transport
BHS01_RS02690	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BHS01_RS02695	COG0470	DNA polymerase III
BHS01_RS02700	COG1774	PSP1 C-terminal conserved region
BHS01_RS02715	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BHS01_RS02725	COG2188	Transcriptional regulator
BHS01_RS02730	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BHS01_RS02735	COG2723	6-phospho-beta-galactosidase activity
BHS01_RS02740	COG1131	(ABC) transporter
BHS01_RS02755	COG2183	response to ionizing radiation
BHS01_RS02760	COG3091	SprT-like family
BHS01_RS02770	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BHS01_RS02780	COG5503	Protein of unknown function (DUF1447)
BHS01_RS02785	COG1214	PFAM Peptidase M22, glycoprotease
BHS01_RS02810	COG2723	6-phospho-beta-galactosidase activity
BHS01_RS02815	COG4209	transmembrane transport
BHS01_RS02820	COG0395	ABC-type sugar transport system, permease component
BHS01_RS02840	COG2081	HI0933 family
BHS01_RS02845	COG2963	transposase activity
BHS01_RS02860	COG1136	(ABC) transporter
BHS01_RS02870	COG0166	Belongs to the GPI family
BHS01_RS02880	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BHS01_RS02885	COG1132	(ABC) transporter
BHS01_RS02890	COG1132	(ABC) transporter
BHS01_RS02895	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BHS01_RS02905	COG0254	rRNA binding
BHS01_RS02930	COG2755	lipolytic protein G-D-S-L family
BHS01_RS02930	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BHS01_RS02935	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BHS01_RS02940	COG2233	PERMEase
BHS01_RS02950	COG0251	oxidation-reduction process
BHS01_RS02955	COG0626	cystathionine gamma-synthase activity
BHS01_RS02965	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BHS01_RS02965	COG0072	phenylalanine-tRNA ligase activity
BHS01_RS02975	COG0446	pyridine nucleotide-disulphide oxidoreductase
BHS01_RS02980	COG2188	Transcriptional regulator
BHS01_RS02985	COG0561	phosphatase activity
BHS01_RS02990	COG1609	Transcriptional regulator
BHS01_RS03010	COG1917	Cupin 2, conserved barrel domain protein
BHS01_RS03010	COG2207	Transcriptional regulator
BHS01_RS03015	COG0673	inositol 2-dehydrogenase activity
BHS01_RS03030	COG0673	inositol 2-dehydrogenase activity
BHS01_RS03035	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BHS01_RS03035	COG1263	PTS System
BHS01_RS03040	COG0366	Alpha amylase catalytic
BHS01_RS03055	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BHS01_RS03065	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BHS01_RS03070	COG0561	phosphatase activity
BHS01_RS03085	COG0527	aspartate kinase activity
BHS01_RS03090	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BHS01_RS03100	COG0359	binds to the 23S rRNA
BHS01_RS03105	COG0305	Participates in initiation and elongation during chromosome replication
BHS01_RS03120	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BHS01_RS03125	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BHS01_RS03135	COG1484	DNA-dependent DNA replication
BHS01_RS03140	COG1160	GTP binding
BHS01_RS03150	COG2723	6-phospho-beta-galactosidase activity
BHS01_RS03155	COG1940	carbohydrate kinase activity
BHS01_RS03160	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BHS01_RS03175	COG0779	Required for maturation of 30S ribosomal subunits
BHS01_RS03180	COG0195	Participates in both transcription termination and antitermination
BHS01_RS03185	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BHS01_RS03195	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BHS01_RS03195	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BHS01_RS03200	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BHS01_RS03205	COG0534	Mate efflux family protein
BHS01_RS03210	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BHS01_RS03215	COG1597	lipid kinase activity
BHS01_RS03230	COG0477	Major facilitator Superfamily
BHS01_RS03335	COG0358	DNA primase activity
BHS01_RS03340	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BHS01_RS03345	COG0542	response to heat
BHS01_RS03350	COG0242	peptide deformylase activity
BHS01_RS03355	COG0556	nucleotide-excision repair
BHS01_RS03365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BHS01_RS03370	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BHS01_RS03375	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BHS01_RS03380	COG1393	Belongs to the ArsC family
BHS01_RS03385	COG0708	Exodeoxyribonuclease III
BHS01_RS03395	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BHS01_RS03395	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BHS01_RS03410	COG0571	ribonuclease III activity
BHS01_RS03415	COG1196	nuclear chromosome segregation
BHS01_RS03420	COG0561	phosphatase activity
BHS01_RS03425	COG0552	protein localization to endoplasmic reticulum
BHS01_RS03430	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BHS01_RS03450	COG0069	glutamate synthase activity
BHS01_RS03450	COG0070	glutamate synthase
BHS01_RS03450	COG0067	glutamate synthase
BHS01_RS03455	COG0493	'glutamate synthase
BHS01_RS03460	COG2151	metal-sulfur cluster biosynthetic enzyme
BHS01_RS03470	COG1131	(ABC) transporter
BHS01_RS03500	COG4585	Histidine kinase
BHS01_RS03505	COG2197	response regulator
BHS01_RS03520	COG1185	polyribonucleotide nucleotidyltransferase activity
BHS01_RS03545	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BHS01_RS03550	COG0765	amino acid transport
BHS01_RS03555	COG1126	abc transporter atp-binding protein
BHS01_RS03565	COG0492	ferredoxin-NADP+ reductase activity
BHS01_RS03575	COG0557	exoribonuclease II activity
BHS01_RS03580	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BHS01_RS03585	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BHS01_RS03590	COG1120	ATPase activity
BHS01_RS03600	COG0492	ferredoxin-NADP+ reductase activity
BHS01_RS03615	COG0573	inorganic phosphate transmembrane transporter activity
BHS01_RS03620	COG0581	inorganic phosphate transmembrane transporter activity
BHS01_RS03625	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BHS01_RS03630	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BHS01_RS03635	COG0704	Plays a role in the regulation of phosphate uptake
BHS01_RS03655	COG1511	domain protein
BHS01_RS03660	COG0561	phosphatase activity
BHS01_RS03665	COG2252	PERMEase
BHS01_RS03675	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BHS01_RS03685	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BHS01_RS03705	COG0363	glucosamine-6-phosphate deaminase activity
BHS01_RS03710	COG1126	abc transporter atp-binding protein
BHS01_RS03715	COG0765	amino acid transport
BHS01_RS03720	COG0006	proline dipeptidase activity
BHS01_RS03725	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BHS01_RS03730	COG1609	Transcriptional regulator
BHS01_RS03740	COG0640	Transcriptional regulator
BHS01_RS03765	COG4209	transmembrane transport
BHS01_RS03770	COG0395	ABC-type sugar transport system, permease component
BHS01_RS03775	COG1653	transport
BHS01_RS03785	COG1609	Transcriptional regulator
BHS01_RS03815	COG1396	sequence-specific DNA binding
BHS01_RS03860	COG1857	crispr-associated protein
BHS01_RS03875	COG1518	maintenance of DNA repeat elements
BHS01_RS03880	COG0488	(ABC) transporter
BHS01_RS03885	COG3118	belongs to the thioredoxin family
BHS01_RS03900	COG4842	Belongs to the WXG100 family
BHS01_RS03925	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BHS01_RS03935	COG0758	DNA mediated transformation
BHS01_RS03945	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BHS01_RS03950	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BHS01_RS03955	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BHS01_RS03960	COG1051	belongs to the nudix hydrolase family
BHS01_RS03965	COG1609	Transcriptional regulator
BHS01_RS03970	COG1621	beta-fructofuranosidase activity
BHS01_RS03980	COG1940	carbohydrate kinase activity
BHS01_RS04005	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BHS01_RS04010	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BHS01_RS04015	COG2884	Cell division ATP-binding protein ftsE
BHS01_RS04020	COG2177	Part of the ABC transporter FtsEX involved in
BHS01_RS04045	COG3716	PTS system mannose fructose sorbose family IID component
BHS01_RS04050	COG3715	PTS system
BHS01_RS04080	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BHS01_RS04090	COG1609	Transcriptional regulator
BHS01_RS04100	COG4209	transmembrane transport
BHS01_RS04105	COG0395	ABC-type sugar transport system, permease component
BHS01_RS04120	COG0745	RESPONSE REGULATOR receiver
BHS01_RS04125	COG5002	protein histidine kinase activity
BHS01_RS04130	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BHS01_RS04140	COG1136	(ABC) transporter
BHS01_RS04145	COG0514	ATP-dependent DNA helicase (RecQ)
BHS01_RS04155	COG4221	oxidoreductase activity
BHS01_RS04165	COG0778	Nitroreductase
BHS01_RS04180	COG1564	THIamine pyrophosphokinase
BHS01_RS04185	COG3682	Transcriptional regulator
BHS01_RS04195	COG2217	Heavy metal translocating P-type atpase
BHS01_RS04205	COG1132	(ABC) transporter
BHS01_RS04210	COG0772	Belongs to the SEDS family
BHS01_RS04215	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BHS01_RS04220	COG0488	(ABC) transporter
BHS01_RS04225	COG0697	spore germination
BHS01_RS04235	COG0187	DNA topoisomerase II activity
BHS01_RS04240	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BHS01_RS04245	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BHS01_RS04250	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BHS01_RS04255	COG0783	Belongs to the Dps family
BHS01_RS04265	COG1940	carbohydrate kinase activity
BHS01_RS04285	COG1217	gtp-binding protein TYPA
BHS01_RS04295	COG0802	atpase or kinase
BHS01_RS04305	COG1316	TRANSCRIPTIONal
BHS01_RS04325	COG0366	Alpha amylase catalytic
BHS01_RS04335	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BHS01_RS04340	COG1609	Transcriptional regulator
BHS01_RS04345	COG1234	tRNA 3'-trailer cleavage
BHS01_RS04360	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BHS01_RS04380	COG1705	Flagellar rod assembly protein muramidase FlgJ
BHS01_RS04380	COG1388	LysM domain
BHS01_RS04415	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BHS01_RS04415	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BHS01_RS04420	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BHS01_RS04430	COG1881	PFAM PEBP family protein
BHS01_RS04475	COG4109	DRTGG domain
BHS01_RS04480	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BHS01_RS04495	COG0670	Belongs to the BI1 family
BHS01_RS04500	COG0039	L-malate dehydrogenase activity
BHS01_RS04505	COG1293	RNA-binding protein homologous to eukaryotic snRNP
BHS01_RS04525	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BHS01_RS04540	COG0481	GTPase activity
BHS01_RS04560	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BHS01_RS04565	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BHS01_RS04570	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BHS01_RS04575	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BHS01_RS04585	COG0415	Belongs to the DNA photolyase family
BHS01_RS04615	COG1215	transferase activity, transferring glycosyl groups
BHS01_RS04640	COG3764	Sortase (surface protein transpeptidase)
BHS01_RS04655	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BHS01_RS04660	COG0196	riboflavin kinase activity
BHS01_RS04665	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BHS01_RS04680	COG0647	UMP catabolic process
BHS01_RS04695	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BHS01_RS04700	COG1481	regulation of sporulation
BHS01_RS04735	COG0372	Belongs to the citrate synthase family
BHS01_RS04740	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BHS01_RS04745	COG0538	isocitrate dehydrogenase activity
BHS01_RS04755	COG1346	cytolysis
BHS01_RS04760	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BHS01_RS04765	COG0187	DNA topoisomerase II activity
BHS01_RS04770	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BHS01_RS04775	COG0569	domain protein
BHS01_RS04780	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BHS01_RS04825	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BHS01_RS04830	COG0564	pseudouridine synthase activity
BHS01_RS04835	COG2205	protein histidine kinase activity
BHS01_RS04840	COG0745	RESPONSE REGULATOR receiver
BHS01_RS04850	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BHS01_RS04855	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BHS01_RS04860	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
BHS01_RS04865	COG1011	Hydrolase
BHS01_RS04870	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BHS01_RS04870	COG0519	Catalyzes the synthesis of GMP from XMP
BHS01_RS04875	COG0450	alkyl hydroperoxide reductase
BHS01_RS04895	COG0789	Transcriptional regulator
BHS01_RS04925	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
BHS01_RS04930	COG1609	Transcriptional regulator
BHS01_RS04940	COG2207	Transcriptional regulator
BHS01_RS04945	COG1653	transport
BHS01_RS04950	COG1175	transmembrane transport
BHS01_RS04955	COG0395	ABC-type sugar transport system, permease component
BHS01_RS04965	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BHS01_RS04970	COG0138	bifunctional purine biosynthesis protein purh
BHS01_RS04975	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BHS01_RS04985	COG1696	Membrane protein involved in D-alanine export
BHS01_RS05000	COG0357	Ribosomal RNA small subunit methyltransferase G
BHS01_RS05020	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BHS01_RS05025	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BHS01_RS05035	COG3853	Toxic anion resistance protein (TelA)
BHS01_RS05050	COG0469	pyruvate kinase activity
BHS01_RS05055	COG0438	transferase activity, transferring glycosyl groups
BHS01_RS05065	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BHS01_RS05075	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BHS01_RS05085	COG0460	homoserine dehydrogenase
BHS01_RS05095	COG2962	Rard protein
BHS01_RS05110	COG1176	ABC-type spermidine putrescine transport system, permease component I
BHS01_RS05115	COG1177	transmembrane transport
BHS01_RS05125	COG1704	LemA family
BHS01_RS05155	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BHS01_RS05165	COG4585	Histidine kinase
BHS01_RS05170	COG2197	response regulator
BHS01_RS05175	COG0577	efflux transmembrane transporter activity
BHS01_RS05175	COG1136	(ABC) transporter
BHS01_RS05185	COG2816	NAD+ diphosphatase activity
BHS01_RS05200	COG0435	Glutathione S-transferase
BHS01_RS05205	COG1737	Transcriptional regulator
BHS01_RS05210	COG1486	melibiose metabolic process
BHS01_RS05245	COG4842	Belongs to the WXG100 family
BHS01_RS05250	COG1132	(ABC) transporter
BHS01_RS05260	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BHS01_RS05265	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BHS01_RS05270	COG1780	Probably involved in ribonucleotide reductase function
BHS01_RS05275	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BHS01_RS05280	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BHS01_RS05290	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BHS01_RS05305	COG3442	glutamine amidotransferase
BHS01_RS05310	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BHS01_RS05315	COG2084	Dehydrogenase
BHS01_RS05320	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BHS01_RS05325	COG1609	Transcriptional regulator
BHS01_RS05330	COG0366	Alpha amylase catalytic
BHS01_RS05335	COG1263	PTS System
BHS01_RS05335	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BHS01_RS05335	COG2190	(PTS) system
BHS01_RS05345	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BHS01_RS05350	COG0668	transmembrane transport
BHS01_RS05355	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BHS01_RS05365	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BHS01_RS05370	COG4974	Belongs to the 'phage' integrase family
BHS01_RS05380	COG1114	Component of the transport system for branched-chain amino acids
BHS01_RS05385	COG0222	ribosome binding
BHS01_RS05390	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BHS01_RS05395	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BHS01_RS05400	COG1187	pseudouridine synthase activity
BHS01_RS05405	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BHS01_RS05410	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BHS01_RS05415	COG4974	Belongs to the 'phage' integrase family
BHS01_RS05435	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BHS01_RS05440	COG3763	UPF0154 protein
BHS01_RS05450	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BHS01_RS05460	COG2205	protein histidine kinase activity
BHS01_RS05465	COG0745	RESPONSE REGULATOR receiver
BHS01_RS05470	COG0577	efflux transmembrane transporter activity
BHS01_RS05475	COG1136	(ABC) transporter
BHS01_RS05485	COG0077	Prephenate dehydratase
BHS01_RS05495	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BHS01_RS05510	COG3493	citrate carrier protein
BHS01_RS05515	COG3290	protein histidine kinase activity
BHS01_RS05520	COG4565	transcriptional regulatory protein
BHS01_RS05525	COG0745	RESPONSE REGULATOR receiver
BHS01_RS05530	COG5002	protein histidine kinase activity
BHS01_RS05535	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BHS01_RS05540	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BHS01_RS05545	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BHS01_RS05555	COG0628	permease
BHS01_RS05560	COG2706	6-phosphogluconolactonase activity
BHS01_RS05570	COG3443	Belongs to the bacterial solute-binding protein 9 family
BHS01_RS05570	COG0803	Belongs to the bacterial solute-binding protein 9 family
BHS01_RS05575	COG1174	glycine betaine transport
BHS01_RS05580	COG1125	glycine betaine transport
BHS01_RS05580	COG0517	IMP dehydrogenase activity
BHS01_RS05585	COG0285	dihydrofolate synthase activity
BHS01_RS05590	COG3527	Alpha-acetolactate decarboxylase
BHS01_RS05595	COG0386	Belongs to the glutathione peroxidase family
BHS01_RS05600	COG1764	response to oxidative stress
BHS01_RS05615	COG0028	Belongs to the TPP enzyme family
BHS01_RS05620	COG0457	Tetratricopeptide repeat
BHS01_RS05625	COG2188	Transcriptional regulator
BHS01_RS05635	COG0268	Binds directly to 16S ribosomal RNA
BHS01_RS05665	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BHS01_RS05675	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BHS01_RS05715	COG0789	Transcriptional regulator
BHS01_RS05725	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BHS01_RS05730	COG0287	Prephenate dehydrogenase
BHS01_RS05735	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BHS01_RS05740	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BHS01_RS05750	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BHS01_RS05760	COG2723	6-phospho-beta-galactosidase activity
BHS01_RS05785	COG0492	ferredoxin-NADP+ reductase activity
BHS01_RS05790	COG0693	protein deglycase activity
BHS01_RS05800	COG2378	regulation of single-species biofilm formation
BHS01_RS05820	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BHS01_RS05835	COG2813	Specifically methylates the guanine in position
BHS01_RS05845	COG1072	(Pantothenic acid kinase))
BHS01_RS05855	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BHS01_RS05860	COG1368	sulfuric ester hydrolase activity
BHS01_RS05870	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BHS01_RS05885	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BHS01_RS05890	COG0488	(ABC) transporter
BHS01_RS05905	COG1307	EDD domain protein, DegV family
BHS01_RS05920	COG0336	Belongs to the RNA methyltransferase TrmD family
BHS01_RS05925	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BHS01_RS05950	COG3052	prosthetic group binding
BHS01_RS05960	COG3493	citrate carrier protein
BHS01_RS05970	COG1396	sequence-specific DNA binding
BHS01_RS05990	COG1051	belongs to the nudix hydrolase family
BHS01_RS06000	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BHS01_RS06005	COG1837	Belongs to the UPF0109 family
BHS01_RS06010	COG0228	four-way junction DNA binding
BHS01_RS06015	COG0516	GMP reductase activity
BHS01_RS06035	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BHS01_RS06040	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BHS01_RS06050	COG0022	dehydrogenase e1 component
BHS01_RS06055	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BHS01_RS06060	COG1078	dGTPase activity
BHS01_RS06075	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BHS01_RS06080	COG2384	SAM-dependent methyltransferase
BHS01_RS06085	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BHS01_RS06140	COG1737	Transcriptional regulator
BHS01_RS06145	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BHS01_RS06145	COG1263	PTS System
BHS01_RS06150	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BHS01_RS06165	COG4493	Belongs to the UPF0637 family
BHS01_RS06170	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BHS01_RS06175	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BHS01_RS06180	COG0488	(ABC) transporter
BHS01_RS06190	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BHS01_RS06205	COG2003	Belongs to the UPF0758 family
BHS01_RS06210	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BHS01_RS06215	COG4605	iron ion homeostasis
BHS01_RS06220	COG4604	ABC transporter, ATP-binding protein
BHS01_RS06225	COG4607	ABC-type enterochelin transport system periplasmic component
BHS01_RS06235	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BHS01_RS06240	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BHS01_RS06250	COG0116	Belongs to the methyltransferase superfamily
BHS01_RS06260	COG3599	regulation of cell shape
BHS01_RS06265	COG0284	orotidine-5'-phosphate decarboxylase activity
BHS01_RS06270	COG0167	dihydroorotate dehydrogenase activity
BHS01_RS06295	COG0505	Belongs to the CarA family
BHS01_RS06300	COG0540	Belongs to the ATCase OTCase family
BHS01_RS06310	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BHS01_RS06320	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BHS01_RS06335	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BHS01_RS06395	COG4842	Belongs to the WXG100 family
BHS01_RS06400	COG0531	amino acid
BHS01_RS06410	COG1695	Transcriptional regulator
BHS01_RS06415	COG0477	Major facilitator Superfamily
BHS01_RS06430	COG4224	UPF0291 protein
BHS01_RS06445	COG1473	amidohydrolase
BHS01_RS06450	COG1466	dna polymerase III delta subunit
BHS01_RS06455	COG1674	ftsk spoiiie
BHS01_RS06460	COG0561	phosphatase activity
BHS01_RS06465	COG0280	phosphate acetyltransferase
BHS01_RS06470	COG0572	uridine kinase
BHS01_RS06520	COG0596	Alpha beta hydrolase
BHS01_RS06525	COG0530	calcium, potassium:sodium antiporter activity
BHS01_RS06555	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BHS01_RS06615	COG4974	Belongs to the 'phage' integrase family
BHS01_RS06620	COG4319	ketosteroid isomerase
BHS01_RS06625	COG4106	trans-aconitate 2-methyltransferase activity
BHS01_RS06645	COG0789	Transcriptional regulator
BHS01_RS06655	COG1063	alcohol dehydrogenase
BHS01_RS06660	COG0589	response to stress
BHS01_RS06670	COG0584	glycerophosphoryl diester phosphodiesterase
BHS01_RS06675	COG0583	DNA-binding transcription factor activity
BHS01_RS06770	COG2801	Transposase and inactivated derivatives
BHS01_RS06775	COG0582	viral genome integration into host DNA
BHS01_RS06780	COG0335	large ribosomal subunit rRNA binding
BHS01_RS06785	COG0277	FAD linked oxidase domain protein
BHS01_RS06790	COG0647	UMP catabolic process
BHS01_RS06800	COG0768	penicillin binding
BHS01_RS06810	COG0275	rRNA processing
BHS01_RS06825	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BHS01_RS06830	COG0497	DNA recombination
BHS01_RS06835	COG1438	arginine binding
BHS01_RS06840	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BHS01_RS06855	COG1570	exodeoxyribonuclease VII activity
BHS01_RS06865	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BHS01_RS06875	COG2211	Major facilitator Superfamily
BHS01_RS06890	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BHS01_RS06895	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BHS01_RS06900	COG0736	holo-[acyl-carrier-protein] synthase activity
BHS01_RS06905	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BHS01_RS06920	COG0596	Alpha beta hydrolase
BHS01_RS06925	COG0539	negative regulation of cytoplasmic translation
BHS01_RS06930	COG0159	tryptophan synthase activity
BHS01_RS06940	COG0133	tryptophan synthase activity
BHS01_RS06950	COG0134	indole-3-glycerol-phosphate synthase activity
BHS01_RS06960	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BHS01_RS06965	COG0512	Glutamine amidotransferase of anthranilate synthase
BHS01_RS06970	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BHS01_RS07025	COG1136	(ABC) transporter
BHS01_RS07050	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BHS01_RS07055	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BHS01_RS07095	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BHS01_RS07100	COG1131	(ABC) transporter
BHS01_RS07125	COG1131	(ABC) transporter
BHS01_RS07145	COG2814	Major facilitator Superfamily
BHS01_RS07150	COG0640	Transcriptional regulator
BHS01_RS07195	COG0482	sulfurtransferase activity
BHS01_RS07200	COG3340	Belongs to the peptidase S51 family
BHS01_RS07215	COG1760	l-serine dehydratase
BHS01_RS07220	COG1760	l-serine dehydratase
BHS01_RS07240	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BHS01_RS07245	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BHS01_RS07255	COG0356	it plays a direct role in the translocation of protons across the membrane
BHS01_RS07270	COG2333	competence protein COMEC
BHS01_RS07270	COG0658	competence protein
BHS01_RS07275	COG0658	competence protein
BHS01_RS07275	COG2333	competence protein COMEC
BHS01_RS07280	COG1555	photosystem II stabilization
BHS01_RS07280	COG1596	polysaccharide export
BHS01_RS07290	COG1668	transmembrane transport
BHS01_RS07295	COG4152	abc transporter atp-binding protein
BHS01_RS07310	COG0443	Heat shock 70 kDa protein
BHS01_RS07315	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BHS01_RS07320	COG1420	regulation of RNA biosynthetic process
BHS01_RS07335	COG0406	alpha-ribazole phosphatase activity
BHS01_RS07340	COG2848	UPF0210 protein
BHS01_RS07345	COG3830	Belongs to the UPF0237 family
BHS01_RS07355	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
BHS01_RS07360	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
BHS01_RS07370	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BHS01_RS07375	COG0439	Biotin carboxylase
BHS01_RS07380	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BHS01_RS07390	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BHS01_RS07395	COG1028	Short-chain dehydrogenase reductase Sdr
BHS01_RS07400	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BHS01_RS07405	COG2070	2-Nitropropane dioxygenase
BHS01_RS07415	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BHS01_RS07430	COG0167	dihydroorotate dehydrogenase activity
BHS01_RS07455	COG0095	Lipoate-protein ligase
BHS01_RS07495	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BHS01_RS07500	COG4122	O-methyltransferase activity
BHS01_RS07510	COG4469	Competence protein
BHS01_RS07515	COG0673	inositol 2-dehydrogenase activity
BHS01_RS07520	COG2759	Belongs to the formate--tetrahydrofolate ligase family
BHS01_RS07545	COG0776	regulation of translation
BHS01_RS07555	COG2755	lipolytic protein G-D-S-L family
BHS01_RS07560	COG1307	EDD domain protein, DegV family
BHS01_RS07565	COG1272	protein, Hemolysin III
BHS01_RS07570	COG2723	6-phospho-beta-galactosidase activity
BHS01_RS07580	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BHS01_RS07580	COG3711	transcriptional antiterminator
BHS01_RS07585	COG1447	Phosphotransferase system cellobiose-specific component IIA
BHS01_RS07595	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BHS01_RS07600	COG0587	DNA-directed DNA polymerase activity
BHS01_RS07610	COG0504	CTP synthase activity
BHS01_RS07635	COG4475	Protein of unknown function (DUF436)
BHS01_RS07640	COG4720	Psort location CytoplasmicMembrane, score
BHS01_RS07645	COG0351	phosphomethylpyrimidine kinase
BHS01_RS07685	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BHS01_RS07690	COG3201	nicotinamide mononucleotide transporter
BHS01_RS07700	COG1254	Belongs to the acylphosphatase family
BHS01_RS07725	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BHS01_RS07735	COG2890	protein-(glutamine-N5) methyltransferase activity
BHS01_RS07740	COG1194	a g-specific adenine glycosylase
BHS01_RS07755	COG4974	Belongs to the 'phage' integrase family
BHS01_RS07785	COG1705	Flagellar rod assembly protein muramidase FlgJ
BHS01_RS07785	COG3942	CHAP domain
BHS01_RS07795	COG0433	COG0433 Predicted ATPase
BHS01_RS07860	COG1674	ftsk spoiiie
BHS01_RS07890	COG1396	sequence-specific DNA binding
BHS01_RS07950	COG1121	(ABC) transporter
BHS01_RS07960	COG2963	transposase activity
BHS01_RS07985	COG1215	transferase activity, transferring glycosyl groups
BHS01_RS07990	COG3706	GGDEF domain
BHS01_RS08000	COG2723	6-phospho-beta-galactosidase activity
BHS01_RS08020	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BHS01_RS08025	COG1447	Phosphotransferase system cellobiose-specific component IIA
BHS01_RS08035	COG3655	Transcriptional regulator
BHS01_RS08040	COG3693	PFAM glycoside hydrolase, family 10
BHS01_RS08040	COG2382	esterase
BHS01_RS08090	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BHS01_RS08105	COG0431	NADPH-dependent FMN reductase
BHS01_RS08105	COG1053	succinate dehydrogenase
BHS01_RS08105	COG3976	FMN-binding domain protein
BHS01_RS08115	COG0583	DNA-binding transcription factor activity
BHS01_RS08120	COG0281	malic enzyme
BHS01_RS08130	COG3158	transport of potassium into the cell
BHS01_RS08135	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BHS01_RS08160	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BHS01_RS08165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BHS01_RS08180	COG0251	oxidation-reduction process
BHS01_RS08185	COG0726	polysaccharide deacetylase
BHS01_RS08190	COG0017	Asparaginyl-tRNA synthetase
BHS01_RS08195	COG0436	Aminotransferase
BHS01_RS08205	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BHS01_RS08205	COG1199	ATP-dependent helicase activity
BHS01_RS08235	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BHS01_RS08240	COG1121	(ABC) transporter
BHS01_RS08245	COG1914	H( )-stimulated, divalent metal cation uptake system
BHS01_RS08260	COG4175	Glycine betaine
BHS01_RS08260	COG3448	diguanylate cyclase activity
BHS01_RS08310	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
BHS01_RS08320	COG1045	serine acetyltransferase
BHS01_RS08335	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BHS01_RS08340	COG1104	cysteine desulfurase activity
BHS01_RS08360	COG0701	Predicted permease
BHS01_RS08365	COG3689	TIGRFAM TIGR03943 family protein
BHS01_RS08370	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BHS01_RS08375	COG0531	amino acid
BHS01_RS08385	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BHS01_RS08390	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BHS01_RS08395	COG0626	cystathionine gamma-synthase activity
BHS01_RS08410	COG3481	metal-dependent phosphohydrolase, HD sub domain
BHS01_RS08430	COG1162	GTPase activity
BHS01_RS08435	COG1942	4-Oxalocrotonate Tautomerase
BHS01_RS08445	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BHS01_RS08450	COG4684	Psort location CytoplasmicMembrane, score
BHS01_RS08455	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BHS01_RS08460	COG0706	membrane insertase activity
BHS01_RS08465	COG1744	ABC transporter substrate-binding protein PnrA-like
BHS01_RS08470	COG3845	ABC transporter
BHS01_RS08475	COG4603	Belongs to the binding-protein-dependent transport system permease family
BHS01_RS08480	COG1079	Belongs to the binding-protein-dependent transport system permease family
BHS01_RS08485	COG0058	SHG alpha-glucan phosphorylase activity
BHS01_RS08490	COG0297	glycogen (starch) synthase activity
BHS01_RS08495	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BHS01_RS08500	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BHS01_RS08505	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BHS01_RS08515	COG1482	cell wall glycoprotein biosynthetic process
BHS01_RS08530	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BHS01_RS08535	COG0006	proline dipeptidase activity
BHS01_RS08540	COG0392	lysyltransferase activity
BHS01_RS08540	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BHS01_RS08545	COG2267	carboxylic ester hydrolase activity
BHS01_RS08565	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BHS01_RS08575	COG4474	Belongs to the UPF0398 family
BHS01_RS08585	COG0641	radical SAM
BHS01_RS08590	COG3119	arylsulfatase activity
BHS01_RS08595	COG1263	PTS System
BHS01_RS08595	COG2190	(PTS) system
BHS01_RS08595	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BHS01_RS08625	COG0582	viral genome integration into host DNA
BHS01_RS08630	COG1028	Short-chain dehydrogenase reductase Sdr
BHS01_RS08640	COG0183	Belongs to the thiolase family
BHS01_RS08645	COG0318	PFAM AMP-dependent synthetase and ligase
BHS01_RS08650	COG1268	BioY protein
BHS01_RS08660	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BHS01_RS08685	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BHS01_RS08690	COG0719	Fe-S assembly protein
BHS01_RS08700	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BHS01_RS08705	COG4862	establishment of competence for transformation
BHS01_RS08710	COG1126	abc transporter atp-binding protein
BHS01_RS08715	COG0765	amino acid transport
BHS01_RS08720	COG3842	ATPase activity
BHS01_RS08725	COG0513	Belongs to the DEAD box helicase family
BHS01_RS08730	COG0066	3-isopropylmalate dehydratase activity
BHS01_RS08735	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BHS01_RS08760	COG1126	abc transporter atp-binding protein
BHS01_RS08765	COG0765	amino acid transport
BHS01_RS08775	COG2239	Acts as a magnesium transporter
BHS01_RS08780	COG0564	pseudouridine synthase activity
BHS01_RS08790	COG2357	RelA SpoT domain protein
BHS01_RS08825	COG4471	UPF0298 protein
BHS01_RS08840	COG1012	belongs to the aldehyde dehydrogenase family
BHS01_RS08855	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BHS01_RS08860	COG3716	PTS system mannose fructose sorbose family IID component
BHS01_RS08870	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BHS01_RS08875	COG1737	Transcriptional regulator
BHS01_RS08880	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BHS01_RS08890	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BHS01_RS08895	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BHS01_RS08900	COG0085	RNA polymerase activity
BHS01_RS08905	COG3590	peptidase
BHS01_RS08910	COG0673	inositol 2-dehydrogenase activity
BHS01_RS08920	COG2244	polysaccharide biosynthetic process
BHS01_RS08925	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BHS01_RS08930	COG0513	Belongs to the DEAD box helicase family
BHS01_RS08945	COG1131	(ABC) transporter
BHS01_RS08985	COG0737	Belongs to the 5'-nucleotidase family
BHS01_RS08990	COG3639	organic phosphonate transmembrane transporter activity
BHS01_RS09000	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BHS01_RS09010	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BHS01_RS09030	COG1447	Phosphotransferase system cellobiose-specific component IIA
BHS01_RS09035	COG2723	6-phospho-beta-galactosidase activity
BHS01_RS09040	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BHS01_RS09045	COG1737	Transcriptional regulator
BHS01_RS09050	COG1181	Belongs to the D-alanine--D-alanine ligase family
BHS01_RS09055	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BHS01_RS09060	COG0768	penicillin binding
BHS01_RS09065	COG1316	TRANSCRIPTIONal
BHS01_RS09080	COG2244	polysaccharide biosynthetic process
BHS01_RS09085	COG1216	Glycosyl transferase, family 2
BHS01_RS09110	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BHS01_RS09115	COG4464	protein tyrosine phosphatase activity
BHS01_RS09120	COG0489	protein tyrosine kinase activity
BHS01_RS09125	COG3944	biosynthesis protein
BHS01_RS09130	COG0588	phosphoglycerate mutase activity
BHS01_RS09135	COG0697	spore germination
BHS01_RS09140	COG1396	sequence-specific DNA binding
BHS01_RS09145	COG0583	DNA-binding transcription factor activity
BHS01_RS09165	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BHS01_RS09175	COG0039	L-malate dehydrogenase activity
BHS01_RS09180	COG3859	Proton-coupled thiamine transporter YuaJ
BHS01_RS09195	COG1268	BioY protein
BHS01_RS09205	COG4443	Transcriptional Coactivator p15 (PC4)
BHS01_RS09220	COG0586	Pfam SNARE associated Golgi protein
BHS01_RS09225	COG0826	peptidase U32
BHS01_RS09240	COG0149	triose-phosphate isomerase activity
BHS01_RS09260	COG0246	Mannitol dehydrogenase
BHS01_RS09265	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BHS01_RS09270	COG3711	transcriptional antiterminator
BHS01_RS09275	COG2213	PTS system mannitol-specific
BHS01_RS09295	COG3338	carbonate dehydratase activity
BHS01_RS09300	COG4473	ABC transporter
BHS01_RS09305	COG1131	(ABC) transporter
BHS01_RS09315	COG0537	adenosine 5'-monophosphoramidase activity
BHS01_RS09330	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BHS01_RS09360	COG1739	Uncharacterized protein family UPF0029
BHS01_RS09365	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BHS01_RS09370	COG1040	competence protein
BHS01_RS09375	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BHS01_RS09380	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BHS01_RS09390	COG1702	phosphate starvation-inducible protein PhoH
BHS01_RS09405	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BHS01_RS09410	COG4608	Belongs to the ABC transporter superfamily
BHS01_RS09415	COG0444	Belongs to the ABC transporter superfamily
BHS01_RS09420	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BHS01_RS09425	COG0601	transmembrane transport
BHS01_RS09430	COG4166	transmembrane transport
BHS01_RS09440	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BHS01_RS09445	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BHS01_RS09450	COG0347	Belongs to the P(II) protein family
BHS01_RS09455	COG0004	ammonium transporteR
BHS01_RS09465	COG0745	RESPONSE REGULATOR receiver
BHS01_RS09470	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BHS01_RS09480	COG1227	inorganic diphosphatase activity
BHS01_RS09485	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BHS01_RS09495	COG1733	regulation of RNA biosynthetic process
BHS01_RS09500	COG0778	Nitroreductase
BHS01_RS09505	COG1132	(ABC) transporter
BHS01_RS09530	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BHS01_RS09540	COG1027	Aspartate ammonia-lyase
BHS01_RS09545	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BHS01_RS09545	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BHS01_RS09545	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BHS01_RS09550	COG1105	Belongs to the carbohydrate kinase PfkB family
BHS01_RS09555	COG1349	DNA-binding transcription factor activity
BHS01_RS09575	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BHS01_RS09580	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BHS01_RS09585	COG0653	protein targeting
BHS01_RS09590	COG3942	CHAP domain
BHS01_RS09600	COG1792	Involved in formation and maintenance of cell shape
BHS01_RS09605	COG0406	alpha-ribazole phosphatase activity
BHS01_RS09605	COG0494	nUDIX hydrolase
BHS01_RS09610	COG2116	formate transmembrane transporter activity
BHS01_RS09615	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BHS01_RS09620	COG1132	(ABC) transporter
BHS01_RS09625	COG1132	(ABC) transporter
BHS01_RS09630	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BHS01_RS09630	COG2207	Transcriptional regulator
BHS01_RS09635	COG0513	Belongs to the DEAD box helicase family
BHS01_RS09665	COG1695	Transcriptional regulator
BHS01_RS09675	COG0702	epimerase
BHS01_RS09680	COG1959	2 iron, 2 sulfur cluster binding
BHS01_RS09690	COG3579	cysteine-type endopeptidase activity
BHS01_RS09700	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BHS01_RS09705	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BHS01_RS09710	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BHS01_RS09720	COG0494	nUDIX hydrolase
BHS01_RS09725	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BHS01_RS09730	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BHS01_RS09735	COG0544	peptidyl-prolyl cis-trans isomerase activity
BHS01_RS09745	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BHS01_RS09750	COG0483	inositol monophosphate 1-phosphatase activity
BHS01_RS09755	COG4476	Belongs to the UPF0223 family
BHS01_RS09760	COG1393	Belongs to the ArsC family
BHS01_RS09770	COG1028	Short-chain dehydrogenase reductase Sdr
BHS01_RS09785	COG0302	gtp cyclohydrolase
BHS01_RS09805	COG2815	serine threonine protein kinase
BHS01_RS09805	COG0515	serine threonine protein kinase
BHS01_RS09810	COG0631	protein serine/threonine phosphatase activity
BHS01_RS09815	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BHS01_RS09815	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BHS01_RS09825	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BHS01_RS09830	COG3279	Response regulator of the LytR AlgR family
BHS01_RS09840	COG1253	flavin adenine dinucleotide binding
BHS01_RS09845	COG0628	permease
BHS01_RS09855	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BHS01_RS09865	COG0084	hydrolase, TatD family'
BHS01_RS09900	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BHS01_RS09910	COG1393	Belongs to the ArsC family
BHS01_RS09935	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BHS01_RS09940	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BHS01_RS09945	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BHS01_RS09950	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BHS01_RS09965	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BHS01_RS09970	COG1426	Protein conserved in bacteria
BHS01_RS09975	COG0612	Peptidase, M16
BHS01_RS09985	COG2501	S4 domain
BHS01_RS09995	COG0549	Belongs to the carbamate kinase family
BHS01_RS10000	COG2957	Belongs to the agmatine deiminase family
BHS01_RS10005	COG0531	amino acid
BHS01_RS10010	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BHS01_RS10015	COG2197	response regulator
BHS01_RS10025	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BHS01_RS10030	COG2814	Major facilitator Superfamily
BHS01_RS10035	COG0301	tRNA thio-modification
BHS01_RS10040	COG1104	cysteine desulfurase activity
BHS01_RS10050	COG1733	regulation of RNA biosynthetic process
BHS01_RS10055	COG1028	Short-chain dehydrogenase reductase Sdr
BHS01_RS10060	COG0025	NhaP-type Na H and K H
BHS01_RS10070	COG0589	response to stress
BHS01_RS10075	COG2195	Cleaves the N-terminal amino acid of tripeptides
BHS01_RS10080	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BHS01_RS10090	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BHS01_RS10100	COG0308	aminopeptidase N
BHS01_RS10105	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BHS01_RS10110	COG0459	protein refolding
BHS01_RS10115	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BHS01_RS10125	COG0072	phenylalanine-tRNA ligase activity
BHS01_RS10125	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BHS01_RS10130	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BHS01_RS10140	COG1363	Peptidase, m42
BHS01_RS10200	COG1216	Glycosyl transferase, family 2
BHS01_RS10200	COG1442	glycosyl transferase family 8
BHS01_RS10215	COG1215	transferase activity, transferring glycosyl groups
BHS01_RS10225	COG1091	dTDP-4-dehydrorhamnose reductase activity
BHS01_RS10230	COG1088	dTDP-glucose 4,6-dehydratase activity
BHS01_RS10240	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BHS01_RS10245	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
BHS01_RS10250	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BHS01_RS10260	COG1335	isochorismatase
BHS01_RS10265	COG1522	sequence-specific DNA binding
BHS01_RS10270	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
BHS01_RS10275	COG1454	alcohol dehydrogenase
BHS01_RS10275	COG1012	belongs to the aldehyde dehydrogenase family
BHS01_RS10280	COG3480	Lon protease (S16) C-terminal proteolytic domain
BHS01_RS10285	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BHS01_RS10290	COG0742	ribosomal rna small subunit methyltransferase
BHS01_RS10395	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BHS01_RS10400	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BHS01_RS10405	COG0049	tRNA binding
BHS01_RS10410	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BHS01_RS10415	COG1686	Belongs to the peptidase S11 family
BHS01_RS10420	COG4975	Glucose uptake
BHS01_RS10435	COG2723	6-phospho-beta-galactosidase activity
BHS01_RS10445	COG2723	6-phospho-beta-galactosidase activity
BHS01_RS10450	COG2190	(PTS) system
BHS01_RS10450	COG1263	PTS System
BHS01_RS10450	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BHS01_RS10455	COG2723	6-phospho-beta-galactosidase activity
BHS01_RS10460	COG2190	(PTS) system
BHS01_RS10460	COG1263	PTS System
BHS01_RS10460	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BHS01_RS10465	COG3711	transcriptional antiterminator
BHS01_RS10470	COG0517	IMP dehydrogenase activity
BHS01_RS10470	COG0516	GMP reductase activity
BHS01_RS10475	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BHS01_RS10500	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BHS01_RS10520	COG0438	transferase activity, transferring glycosyl groups
BHS01_RS10535	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BHS01_RS10555	COG3711	transcriptional antiterminator
BHS01_RS10560	COG2190	(PTS) system
BHS01_RS10560	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BHS01_RS10560	COG1263	PTS System
BHS01_RS10570	COG0789	Transcriptional regulator
BHS01_RS10575	COG2814	Major facilitator Superfamily
BHS01_RS10585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BHS01_RS10600	COG4555	ABC transporter
BHS01_RS10640	COG1316	TRANSCRIPTIONal
BHS01_RS10690	COG0438	transferase activity, transferring glycosyl groups
BHS01_RS10695	COG0438	transferase activity, transferring glycosyl groups
BHS01_RS10710	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BHS01_RS10715	COG4464	protein tyrosine phosphatase activity
BHS01_RS10720	COG0489	protein tyrosine kinase activity
BHS01_RS10790	COG1674	ftsk spoiiie
BHS01_RS10840	COG0433	COG0433 Predicted ATPase
BHS01_RS10850	COG1705	Flagellar rod assembly protein muramidase FlgJ
BHS01_RS10850	COG3942	CHAP domain
BHS01_RS10870	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BHS01_RS10875	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BHS01_RS10880	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BHS01_RS10885	COG0681	Belongs to the peptidase S26 family
BHS01_RS10900	COG0107	imidazoleglycerol-phosphate synthase activity
BHS01_RS10910	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BHS01_RS10915	COG0131	Imidazoleglycerol-phosphate dehydratase
BHS01_RS10920	COG0560	Phosphoserine phosphatase
BHS01_RS10925	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BHS01_RS10930	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BHS01_RS10935	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BHS01_RS10945	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BHS01_RS10950	COG1242	4 iron, 4 sulfur cluster binding
BHS01_RS10955	COG0671	phosphoesterase, PA-phosphatase related
BHS01_RS11040	COG2755	lipolytic protein G-D-S-L family
BHS01_RS11040	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BHS01_RS11050	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BHS01_RS11060	COG0037	tRNA processing
BHS01_RS11070	COG2368	4-hydroxyphenylacetate
BHS01_RS11085	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BHS01_RS11090	COG4481	Protein conserved in bacteria
BHS01_RS11095	COG0012	GTP binding
BHS01_RS11105	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BHS01_RS11110	COG2244	polysaccharide biosynthetic process
BHS01_RS11115	COG1074	ATP-dependent DNA helicase activity
BHS01_RS11120	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BHS01_RS11125	COG0592	DNA-directed DNA polymerase activity