locus-tag	class	description
Verru16B_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
Verru16B_RS00015	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Verru16B_RS00075	COG0196	riboflavin kinase activity
Verru16B_RS00080	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
Verru16B_RS00085	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
Verru16B_RS00090	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
Verru16B_RS00095	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
Verru16B_RS00100	COG0195	Participates in both transcription termination and antitermination
Verru16B_RS00115	COG2738	Putative neutral zinc metallopeptidase
Verru16B_RS00120	COG0339	signal peptide processing
Verru16B_RS00150	COG2890	protein-(glutamine-N5) methyltransferase activity
Verru16B_RS00185	COG1595	DNA-templated transcription, initiation
Verru16B_RS00190	COG4191	Histidine kinase
Verru16B_RS00230	COG2814	Major facilitator Superfamily
Verru16B_RS00240	COG0828	Belongs to the bacterial ribosomal protein bS21 family
Verru16B_RS00250	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
Verru16B_RS00250	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Verru16B_RS00280	COG2207	Transcriptional regulator
Verru16B_RS00280	COG3708	Transcriptional regulator
Verru16B_RS00300	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
Verru16B_RS00315	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Verru16B_RS00320	COG0673	inositol 2-dehydrogenase activity
Verru16B_RS00340	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
Verru16B_RS00345	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
Verru16B_RS00390	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
Verru16B_RS00410	COG1612	heme a metabolic process
Verru16B_RS00415	COG0109	protoheme IX farnesyltransferase activity
Verru16B_RS00420	COG2322	membrane
Verru16B_RS00425	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
Verru16B_RS00430	COG2010	Cytochrome c
Verru16B_RS00430	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
Verru16B_RS00440	COG1845	cytochrome c oxidase, subunit III
Verru16B_RS00470	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Verru16B_RS00485	COG1116	anion transmembrane transporter activity
Verru16B_RS00505	COG1959	2 iron, 2 sulfur cluster binding
Verru16B_RS00510	COG0471	metal ion transport
Verru16B_RS00510	COG3273	potassium ion transport
Verru16B_RS00520	COG3534	alpha-L-arabinofuranosidase
Verru16B_RS00540	COG0459	protein refolding
Verru16B_RS00545	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
Verru16B_RS00550	COG0443	Heat shock 70 kDa protein
Verru16B_RS00565	COG2204	response regulator
Verru16B_RS00570	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Verru16B_RS00580	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
Verru16B_RS00600	COG0825	malonyl-CoA metabolic process
Verru16B_RS00610	COG3250	beta-galactosidase activity
Verru16B_RS00620	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
Verru16B_RS00635	COG1385	rRNA (uridine-N3-)-methyltransferase activity
Verru16B_RS00645	COG2877	3-deoxy-8-phosphooctulonate synthase activity
Verru16B_RS00650	COG0504	CTP synthase activity
Verru16B_RS00660	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Verru16B_RS00680	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
Verru16B_RS00680	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
Verru16B_RS00685	COG1131	(ABC) transporter
Verru16B_RS00715	COG3119	arylsulfatase activity
Verru16B_RS00745	COG0242	peptide deformylase activity
Verru16B_RS00750	COG2096	Adenosyltransferase
Verru16B_RS00760	COG0673	inositol 2-dehydrogenase activity
Verru16B_RS00775	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
Verru16B_RS00795	COG0514	ATP-dependent DNA helicase (RecQ)
Verru16B_RS00870	COG1704	LemA family
Verru16B_RS00885	COG1181	Belongs to the D-alanine--D-alanine ligase family
Verru16B_RS00900	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
Verru16B_RS00980	COG0724	RNA recognition motif
Verru16B_RS00990	COG0545	Peptidyl-prolyl cis-trans isomerase
Verru16B_RS00995	COG0640	Transcriptional regulator
Verru16B_RS01035	COG0346	lactoylglutathione lyase activity
Verru16B_RS01045	COG4771	TonB-dependent receptor
Verru16B_RS01060	COG2755	lipolytic protein G-D-S-L family
Verru16B_RS01060	COG0657	acetylesterase activity
Verru16B_RS01080	COG0667	Aldo Keto reductase
Verru16B_RS01105	COG1187	pseudouridine synthase activity
Verru16B_RS01120	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Verru16B_RS01125	COG1272	protein, Hemolysin III
Verru16B_RS01140	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Verru16B_RS01145	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Verru16B_RS01145	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Verru16B_RS01175	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
Verru16B_RS01180	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Verru16B_RS01190	COG1262	PFAM Formylglycine-generating sulfatase enzyme
Verru16B_RS01195	COG3119	arylsulfatase activity
Verru16B_RS01200	COG3119	arylsulfatase activity
Verru16B_RS01240	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Verru16B_RS01245	COG1764	response to oxidative stress
Verru16B_RS01260	COG4989	oxidoreductase activity
Verru16B_RS01280	COG0824	Thioesterase
Verru16B_RS01285	COG0275	rRNA processing
Verru16B_RS01300	COG0218	Necessary for normal cell division and for the maintenance of normal septation
Verru16B_RS01315	COG2207	Transcriptional regulator
Verru16B_RS01315	COG1609	Transcriptional regulator
Verru16B_RS01340	COG4948	Mandelate Racemase Muconate Lactonizing
Verru16B_RS01345	COG2226	methyltransferase
Verru16B_RS01375	COG0739	heme binding
Verru16B_RS01380	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
Verru16B_RS01395	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Verru16B_RS01410	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Verru16B_RS01415	COG0823	Involved in the tonB-independent uptake of proteins
Verru16B_RS01420	COG4124	Belongs to the glycosyl hydrolase 26 family
Verru16B_RS01440	COG0784	Response regulator, receiver
Verru16B_RS01440	COG5002	protein histidine kinase activity
Verru16B_RS01450	COG2204	response regulator
Verru16B_RS01490	COG1595	DNA-templated transcription, initiation
Verru16B_RS01525	COG2226	methyltransferase
Verru16B_RS01545	COG4968	Prepilin-type N-terminal cleavage methylation domain
Verru16B_RS01580	COG4106	trans-aconitate 2-methyltransferase activity
Verru16B_RS01595	COG3655	Transcriptional regulator
Verru16B_RS01615	COG1064	alcohol dehydrogenase
Verru16B_RS01625	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
Verru16B_RS01635	COG0589	response to stress
Verru16B_RS01640	COG0673	inositol 2-dehydrogenase activity
Verru16B_RS01650	COG0039	L-malate dehydrogenase activity
Verru16B_RS01660	COG0277	FAD linked oxidase domain protein
Verru16B_RS01660	COG0247	lactate metabolic process
Verru16B_RS01665	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
Verru16B_RS01680	COG4585	Histidine kinase
Verru16B_RS01685	COG2197	response regulator
Verru16B_RS01690	COG0006	proline dipeptidase activity
Verru16B_RS01705	COG0348	domain, Protein
Verru16B_RS01710	COG2010	Cytochrome c
Verru16B_RS01715	COG3278	Belongs to the heme-copper respiratory oxidase family
Verru16B_RS01730	COG2207	Transcriptional regulator
Verru16B_RS01730	COG0662	Cupin 2, conserved barrel domain protein
Verru16B_RS01740	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
Verru16B_RS01745	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Verru16B_RS01760	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
Verru16B_RS01780	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
Verru16B_RS01790	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Verru16B_RS01795	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
Verru16B_RS01800	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Verru16B_RS01820	COG1262	PFAM Formylglycine-generating sulfatase enzyme
Verru16B_RS01840	COG0805	protein transport
Verru16B_RS01845	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Verru16B_RS01845	COG0574	Belongs to the PEP-utilizing enzyme family
Verru16B_RS01890	COG2814	Major facilitator Superfamily
Verru16B_RS01930	COG0488	(ABC) transporter
Verru16B_RS01940	COG2514	catechol 2,3-dioxygenase activity
Verru16B_RS01955	COG2204	response regulator
Verru16B_RS01970	COG0385	Bile acid
Verru16B_RS01980	COG2308	Evidence 4 Homologs of previously reported genes of
Verru16B_RS01980	COG2307	Protein conserved in bacteria
Verru16B_RS01985	COG1305	Transglutaminase-like
Verru16B_RS02000	COG2378	regulation of single-species biofilm formation
Verru16B_RS02010	COG1136	(ABC) transporter
Verru16B_RS02035	COG0674	pyruvate-flavodoxin oxidoreductase activity
Verru16B_RS02035	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
Verru16B_RS02040	COG1013	pyruvate-flavodoxin oxidoreductase activity
Verru16B_RS02050	COG1435	thymidine kinase activity
Verru16B_RS02055	COG0427	acetyl-CoA hydrolase
Verru16B_RS02060	COG0427	acetyl-CoA hydrolase
Verru16B_RS02065	COG3408	Glycogen debranching enzyme
Verru16B_RS02065	COG3119	arylsulfatase activity
Verru16B_RS02070	COG2706	6-phosphogluconolactonase activity
Verru16B_RS02085	COG0815	Transfers the fatty acyl group on membrane lipoproteins
Verru16B_RS02095	COG0653	protein targeting
Verru16B_RS02100	COG2308	Evidence 4 Homologs of previously reported genes of
Verru16B_RS02125	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Verru16B_RS02135	COG1288	antiporter activity
Verru16B_RS02150	COG0343	queuine tRNA-ribosyltransferase activity
Verru16B_RS02160	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Verru16B_RS02170	COG0537	adenosine 5'-monophosphoramidase activity
Verru16B_RS02180	COG0758	DNA mediated transformation
Verru16B_RS02180	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Verru16B_RS02185	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
Verru16B_RS02185	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
Verru16B_RS02195	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
Verru16B_RS02215	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Verru16B_RS02215	COG0519	Catalyzes the synthesis of GMP from XMP
Verru16B_RS02225	COG0203	ribosomal protein L17
Verru16B_RS02230	COG0202	RNA polymerase activity
Verru16B_RS02235	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
Verru16B_RS02240	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
Verru16B_RS02245	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Verru16B_RS02255	COG0563	adenylate kinase activity
Verru16B_RS02265	COG0200	Binds to the 23S rRNA
Verru16B_RS02270	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
Verru16B_RS02275	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
Verru16B_RS02280	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
Verru16B_RS02285	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
Verru16B_RS02290	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
Verru16B_RS02295	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Verru16B_RS02300	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
Verru16B_RS02305	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
Verru16B_RS02310	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
Verru16B_RS02315	COG0255	Belongs to the universal ribosomal protein uL29 family
Verru16B_RS02320	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
Verru16B_RS02325	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
Verru16B_RS02330	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
Verru16B_RS02335	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
Verru16B_RS02340	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Verru16B_RS02345	COG0089	rRNA binding
Verru16B_RS02350	COG0088	Forms part of the polypeptide exit tunnel
Verru16B_RS02355	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
Verru16B_RS02360	COG0051	transcription antitermination factor activity, RNA binding
Verru16B_RS02365	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Verru16B_RS02370	COG0049	tRNA binding
Verru16B_RS02375	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
Verru16B_RS02385	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Verru16B_RS02390	COG0085	RNA polymerase activity
Verru16B_RS02395	COG0222	ribosome binding
Verru16B_RS02400	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
Verru16B_RS02405	COG0081	regulation of translation
Verru16B_RS02410	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
Verru16B_RS02430	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Verru16B_RS02450	COG0811	peptide transport
Verru16B_RS02460	COG1704	LemA family
Verru16B_RS02470	COG0501	Belongs to the peptidase M48B family
Verru16B_RS02485	COG0583	DNA-binding transcription factor activity
Verru16B_RS02510	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
Verru16B_RS02515	COG0281	malic enzyme
Verru16B_RS02535	COG1215	transferase activity, transferring glycosyl groups
Verru16B_RS02545	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Verru16B_RS02560	COG3047	cAMP biosynthetic process
Verru16B_RS02565	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
Verru16B_RS02620	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Verru16B_RS02625	COG2255	four-way junction helicase activity
Verru16B_RS02655	COG2205	protein histidine kinase activity
Verru16B_RS02660	COG0745	RESPONSE REGULATOR receiver
Verru16B_RS02685	COG0840	transmembrane signaling receptor activity
Verru16B_RS02690	COG1469	GTP cyclohydrolase I activity
Verru16B_RS02700	COG1234	tRNA 3'-trailer cleavage
Verru16B_RS02715	COG1253	flavin adenine dinucleotide binding
Verru16B_RS02725	COG0523	cobalamin synthesis protein
Verru16B_RS02745	COG3852	Histidine kinase
Verru16B_RS02840	COG0702	epimerase
Verru16B_RS02870	COG0733	neurotransmitter:sodium symporter activity
Verru16B_RS02875	COG0326	Molecular chaperone. Has ATPase activity
Verru16B_RS02900	COG0515	serine threonine protein kinase
Verru16B_RS02930	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
Verru16B_RS02935	COG0052	Belongs to the universal ribosomal protein uS2 family
Verru16B_RS02940	COG1172	Belongs to the binding-protein-dependent transport system permease family
Verru16B_RS02945	COG1879	ABC-type sugar transport system periplasmic component
Verru16B_RS02950	COG1129	ABC transporter
Verru16B_RS02970	COG1013	pyruvate-flavodoxin oxidoreductase activity
Verru16B_RS02970	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
Verru16B_RS02970	COG0674	pyruvate-flavodoxin oxidoreductase activity
Verru16B_RS02975	COG3458	cephalosporin-C deacetylase activity
Verru16B_RS02985	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
Verru16B_RS02995	COG2211	Major facilitator Superfamily
Verru16B_RS03000	COG2211	Major facilitator Superfamily
Verru16B_RS03005	COG2207	Transcriptional regulator
Verru16B_RS03005	COG1609	Transcriptional regulator
Verru16B_RS03010	COG4774	siderophore transport
Verru16B_RS03040	COG0667	Aldo Keto reductase
Verru16B_RS03045	COG1609	Transcriptional regulator
Verru16B_RS03050	COG2115	Belongs to the xylose isomerase family
Verru16B_RS03060	COG2211	Major facilitator Superfamily
Verru16B_RS03075	COG3661	Belongs to the glycosyl hydrolase 67 family
Verru16B_RS03080	COG3507	Belongs to the glycosyl hydrolase 43 family
Verru16B_RS03095	COG0673	inositol 2-dehydrogenase activity
Verru16B_RS03100	COG0823	Involved in the tonB-independent uptake of proteins
Verru16B_RS03110	COG1410	methionine synthase
Verru16B_RS03110	COG0646	methionine synthase
Verru16B_RS03115	COG5012	cobalamin binding
Verru16B_RS03120	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
Verru16B_RS03140	COG1312	Catalyzes the dehydration of D-mannonate
Verru16B_RS03210	COG4774	siderophore transport
Verru16B_RS03215	COG1070	Carbohydrate kinase
Verru16B_RS03225	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Verru16B_RS03235	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Verru16B_RS03235	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Verru16B_RS03245	COG1297	OPT oligopeptide transporter protein
Verru16B_RS03250	COG1297	OPT oligopeptide transporter protein
Verru16B_RS03255	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
Verru16B_RS03260	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
Verru16B_RS03265	COG0436	Aminotransferase
Verru16B_RS03305	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Verru16B_RS03330	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Verru16B_RS03340	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
Verru16B_RS03380	COG0457	Tetratricopeptide repeat
Verru16B_RS03385	COG0726	polysaccharide deacetylase
Verru16B_RS03385	COG1649	PFAM Uncharacterised BCR, COG1649
Verru16B_RS03390	COG1215	transferase activity, transferring glycosyl groups
Verru16B_RS03420	COG2995	paraquat-inducible protein a
Verru16B_RS03455	COG1506	peptidase
Verru16B_RS03455	COG0823	Involved in the tonB-independent uptake of proteins
Verru16B_RS03455	COG4946	Tricorn protease homolog
Verru16B_RS03480	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Verru16B_RS03490	COG2197	response regulator
Verru16B_RS03495	COG5002	protein histidine kinase activity
Verru16B_RS03495	COG3850	Histidine kinase
Verru16B_RS03515	COG1506	peptidase
Verru16B_RS03515	COG0823	Involved in the tonB-independent uptake of proteins
Verru16B_RS03525	COG0308	aminopeptidase N
Verru16B_RS03575	COG4783	chaperone-mediated protein folding
Verru16B_RS03635	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Verru16B_RS03640	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Verru16B_RS03655	COG1509	lysine 2,3-aminomutase activity
Verru16B_RS03660	COG0784	Response regulator, receiver
Verru16B_RS03660	COG5002	protein histidine kinase activity
Verru16B_RS03660	COG2205	protein histidine kinase activity
Verru16B_RS03665	COG0505	Belongs to the CarA family
Verru16B_RS03670	COG0840	transmembrane signaling receptor activity
Verru16B_RS03680	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
Verru16B_RS03685	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Verru16B_RS03690	COG0084	hydrolase, TatD family'
Verru16B_RS03705	COG1393	Belongs to the ArsC family
Verru16B_RS03730	COG1643	Atp-dependent helicase
Verru16B_RS03790	COG2169	Transcriptional regulator
Verru16B_RS03790	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Verru16B_RS03800	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
Verru16B_RS03855	COG0653	protein targeting
Verru16B_RS03865	COG1566	PFAM secretion protein HlyD family protein
Verru16B_RS03875	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
Verru16B_RS03880	COG0009	L-threonylcarbamoyladenylate synthase
Verru16B_RS03900	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Verru16B_RS03905	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Verru16B_RS03920	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
Verru16B_RS03935	COG0513	Belongs to the DEAD box helicase family
Verru16B_RS03960	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Verru16B_RS03970	COG0697	spore germination
Verru16B_RS03985	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Verru16B_RS03995	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
Verru16B_RS04010	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
Verru16B_RS04015	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
Verru16B_RS04035	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
Verru16B_RS04040	COG1053	succinate dehydrogenase
Verru16B_RS04095	COG0788	formyltetrahydrofolate deformylase activity
Verru16B_RS04100	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Verru16B_RS04105	COG2204	response regulator
Verru16B_RS04110	COG1459	type II secretion system
Verru16B_RS04125	COG2197	response regulator
Verru16B_RS04130	COG1385	rRNA (uridine-N3-)-methyltransferase activity
Verru16B_RS04135	COG0742	ribosomal rna small subunit methyltransferase
Verru16B_RS04145	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Verru16B_RS04150	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
Verru16B_RS04175	COG3275	phosphorelay sensor kinase activity
Verru16B_RS04180	COG4166	transmembrane transport
Verru16B_RS04185	COG0137	argininosuccinate synthase activity
Verru16B_RS04195	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
Verru16B_RS04200	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Verru16B_RS04205	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Verru16B_RS04210	COG0019	diaminopimelate decarboxylase activity
Verru16B_RS04215	COG5310	Homospermidine synthase
Verru16B_RS04220	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
Verru16B_RS04225	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
Verru16B_RS04235	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
Verru16B_RS04250	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
Verru16B_RS04265	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
Verru16B_RS04270	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
Verru16B_RS04285	COG1595	DNA-templated transcription, initiation
Verru16B_RS04290	COG1012	belongs to the aldehyde dehydrogenase family
Verru16B_RS04310	COG1639	'signal transduction protein
Verru16B_RS04320	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
Verru16B_RS04325	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
Verru16B_RS04345	COG0523	cobalamin synthesis protein
Verru16B_RS04360	COG4774	siderophore transport
Verru16B_RS04370	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Verru16B_RS04375	COG1121	(ABC) transporter
Verru16B_RS04380	COG0803	Belongs to the bacterial solute-binding protein 9 family
Verru16B_RS04395	COG0523	cobalamin synthesis protein
Verru16B_RS04405	COG1120	ATPase activity
Verru16B_RS04420	COG4774	siderophore transport
Verru16B_RS04430	COG4771	TonB-dependent receptor
Verru16B_RS04455	COG1136	(ABC) transporter
Verru16B_RS04460	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
Verru16B_RS04500	COG2133	pyrroloquinoline quinone binding
Verru16B_RS04505	COG4774	siderophore transport
Verru16B_RS04540	COG0848	biopolymer transport protein
Verru16B_RS04545	COG0811	peptide transport
Verru16B_RS04550	COG0811	peptide transport
Verru16B_RS04560	COG0667	Aldo Keto reductase
Verru16B_RS04590	COG0745	RESPONSE REGULATOR receiver
Verru16B_RS04600	COG1331	Highly conserved protein containing a thioredoxin domain
Verru16B_RS04605	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Verru16B_RS04610	COG0488	(ABC) transporter
Verru16B_RS04615	COG1733	regulation of RNA biosynthetic process
Verru16B_RS04630	COG2329	Antibiotic biosynthesis monooxygenase
Verru16B_RS04650	COG4555	ABC transporter
Verru16B_RS04655	COG3279	Response regulator of the LytR AlgR family
Verru16B_RS04660	COG3275	phosphorelay sensor kinase activity
Verru16B_RS04665	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Verru16B_RS04690	COG1012	belongs to the aldehyde dehydrogenase family
Verru16B_RS04705	COG1012	belongs to the aldehyde dehydrogenase family
Verru16B_RS04730	COG2962	Rard protein
Verru16B_RS04740	COG0545	Peptidyl-prolyl cis-trans isomerase
Verru16B_RS04745	COG1686	Belongs to the peptidase S11 family
Verru16B_RS04750	COG0724	RNA recognition motif
Verru16B_RS04780	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Verru16B_RS04815	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Verru16B_RS04820	COG0583	DNA-binding transcription factor activity
Verru16B_RS04830	COG2912	Transglutaminase-like superfamily
Verru16B_RS04835	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Verru16B_RS04840	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
Verru16B_RS04875	COG0494	nUDIX hydrolase
Verru16B_RS04885	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
Verru16B_RS04900	COG0438	transferase activity, transferring glycosyl groups
Verru16B_RS04910	COG4585	Histidine kinase
Verru16B_RS04915	COG2197	response regulator
Verru16B_RS04930	COG3250	beta-galactosidase activity
Verru16B_RS04945	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Verru16B_RS04980	COG0217	transcriptional regulatory protein
Verru16B_RS04985	COG0519	Catalyzes the synthesis of GMP from XMP
Verru16B_RS05025	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
Verru16B_RS05030	COG0673	inositol 2-dehydrogenase activity
Verru16B_RS05040	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
Verru16B_RS05040	COG0116	Belongs to the methyltransferase superfamily
Verru16B_RS05050	COG4821	SIS domain
Verru16B_RS05055	COG2971	BadF BadG BcrA BcrD
Verru16B_RS05125	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
Verru16B_RS05130	COG0445	tRNA wobble uridine modification
Verru16B_RS05135	COG0745	RESPONSE REGULATOR receiver
Verru16B_RS05140	COG5002	protein histidine kinase activity
Verru16B_RS05145	COG0220	tRNA (guanine-N7-)-methyltransferase activity
Verru16B_RS05150	COG0356	it plays a direct role in the translocation of protons across the membrane
Verru16B_RS05160	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
Verru16B_RS05165	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Verru16B_RS05170	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
Verru16B_RS05175	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
Verru16B_RS05180	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
Verru16B_RS05185	COG0355	proton-transporting ATP synthase activity, rotational mechanism
Verru16B_RS05205	COG0784	Response regulator, receiver
Verru16B_RS05205	COG5002	protein histidine kinase activity
Verru16B_RS05215	COG0604	alcohol dehydrogenase
Verru16B_RS05250	COG3932	Exopolysaccharide synthesis, ExoD
Verru16B_RS05255	COG0602	queuosine metabolic process
Verru16B_RS05260	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
Verru16B_RS05265	COG0584	glycerophosphoryl diester phosphodiesterase
Verru16B_RS05270	COG0123	including yeast histone deacetylase and acetoin utilization protein
Verru16B_RS05280	COG0318	PFAM AMP-dependent synthetase and ligase
Verru16B_RS05285	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Verru16B_RS05290	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Verru16B_RS05300	COG1506	peptidase
Verru16B_RS05300	COG0823	Involved in the tonB-independent uptake of proteins
Verru16B_RS05315	COG0259	pyridoxamine-phosphate oxidase activity
Verru16B_RS05320	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Verru16B_RS05325	COG2095	MarC family integral membrane protein
Verru16B_RS05330	COG3852	Histidine kinase
Verru16B_RS05340	COG1090	epimerase
Verru16B_RS05345	COG0820	rRNA (adenine-C2-)-methyltransferase activity
Verru16B_RS05365	COG0784	Response regulator, receiver
Verru16B_RS05365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Verru16B_RS05365	COG2198	Histidine kinase
Verru16B_RS05365	COG2205	protein histidine kinase activity
Verru16B_RS05375	COG0745	RESPONSE REGULATOR receiver
Verru16B_RS05390	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Verru16B_RS05390	COG2198	Histidine kinase
Verru16B_RS05390	COG2205	protein histidine kinase activity
Verru16B_RS05390	COG0784	Response regulator, receiver
Verru16B_RS05395	COG2197	response regulator
Verru16B_RS05410	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Verru16B_RS05440	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
Verru16B_RS05490	COG1846	Transcriptional regulator
Verru16B_RS05665	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
Verru16B_RS05680	COG0592	DNA-directed DNA polymerase activity
Verru16B_RS05685	COG1183	phosphatidylcholine synthase activity
Verru16B_RS05695	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Verru16B_RS05715	COG0501	Belongs to the peptidase M48B family
Verru16B_RS05745	COG2985	domain, Protein
Verru16B_RS05745	COG0569	domain protein
Verru16B_RS05785	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Verru16B_RS05825	COG0612	Peptidase, M16
Verru16B_RS05830	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
Verru16B_RS05830	COG0140	phosphoribosyl-ATP diphosphatase activity
Verru16B_RS05835	COG0107	imidazoleglycerol-phosphate synthase activity
Verru16B_RS05845	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
Verru16B_RS05850	COG0131	Imidazoleglycerol-phosphate dehydratase
Verru16B_RS05850	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
Verru16B_RS05855	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Verru16B_RS05860	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
Verru16B_RS05875	COG0745	RESPONSE REGULATOR receiver
Verru16B_RS05885	COG1368	sulfuric ester hydrolase activity
Verru16B_RS05890	COG1368	sulfuric ester hydrolase activity
Verru16B_RS05910	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
Verru16B_RS05925	COG2890	protein-(glutamine-N5) methyltransferase activity
Verru16B_RS05955	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Verru16B_RS05975	COG0640	Transcriptional regulator
Verru16B_RS05980	COG1803	Methylglyoxal synthase
Verru16B_RS05995	COG0706	membrane insertase activity
Verru16B_RS06000	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
Verru16B_RS06005	COG0594	ribonuclease P activity
Verru16B_RS06010	COG0230	Belongs to the bacterial ribosomal protein bL34 family
Verru16B_RS06020	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Verru16B_RS06035	COG2995	paraquat-inducible protein a
Verru16B_RS06040	COG1959	2 iron, 2 sulfur cluster binding
Verru16B_RS06045	COG2895	sulfate adenylyltransferase (ATP) activity
Verru16B_RS06055	COG0175	sulfate reduction
Verru16B_RS06060	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Verru16B_RS06065	COG1648	precorrin-2 dehydrogenase activity
Verru16B_RS06065	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Verru16B_RS06090	COG1028	Short-chain dehydrogenase reductase Sdr
Verru16B_RS06095	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
Verru16B_RS06100	COG0322	excinuclease ABC activity
Verru16B_RS06105	COG1546	Belongs to the CinA family
Verru16B_RS06105	COG1058	Belongs to the CinA family
Verru16B_RS06115	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Verru16B_RS06120	COG0205	6-phosphofructokinase activity
Verru16B_RS06130	COG0545	Peptidyl-prolyl cis-trans isomerase
Verru16B_RS06145	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
Verru16B_RS06180	COG1028	Short-chain dehydrogenase reductase Sdr
Verru16B_RS06185	COG0673	inositol 2-dehydrogenase activity
Verru16B_RS06205	COG0235	Class ii aldolase
Verru16B_RS06210	COG2160	L-arabinose isomerase activity
Verru16B_RS06215	COG1069	ribulokinase activity
Verru16B_RS06235	COG1073	alpha beta
Verru16B_RS06265	COG1028	Short-chain dehydrogenase reductase Sdr
Verru16B_RS06270	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Verru16B_RS06280	COG0673	inositol 2-dehydrogenase activity
Verru16B_RS06290	COG0673	inositol 2-dehydrogenase activity
Verru16B_RS06295	COG1129	ABC transporter
Verru16B_RS06300	COG1172	Belongs to the binding-protein-dependent transport system permease family
Verru16B_RS06305	COG1172	Belongs to the binding-protein-dependent transport system permease family
Verru16B_RS06310	COG1879	ABC-type sugar transport system periplasmic component
Verru16B_RS06340	COG2755	lipolytic protein G-D-S-L family
Verru16B_RS06350	COG3254	rhamnose metabolic process
Verru16B_RS06365	COG3507	Belongs to the glycosyl hydrolase 43 family
Verru16B_RS06365	COG2382	esterase
Verru16B_RS06365	COG3693	PFAM glycoside hydrolase, family 10
Verru16B_RS06390	COG2382	esterase
Verru16B_RS06395	COG1082	Xylose isomerase domain protein TIM barrel
Verru16B_RS06405	COG1472	Belongs to the glycosyl hydrolase 3 family
Verru16B_RS06420	COG2382	esterase
Verru16B_RS06440	COG0657	acetylesterase activity
Verru16B_RS06440	COG2755	lipolytic protein G-D-S-L family
Verru16B_RS06445	COG2382	esterase
Verru16B_RS06465	COG2755	lipolytic protein G-D-S-L family
Verru16B_RS06485	COG3940	Belongs to the glycosyl hydrolase 43 family
Verru16B_RS06505	COG1874	Beta-galactosidase
Verru16B_RS06515	COG3347	Dehydrogenase
Verru16B_RS06515	COG1028	Short-chain dehydrogenase reductase Sdr
Verru16B_RS06595	COG2814	Major facilitator Superfamily
Verru16B_RS06615	COG1063	alcohol dehydrogenase
Verru16B_RS06625	COG1028	Short-chain dehydrogenase reductase Sdr
Verru16B_RS06640	COG1028	Short-chain dehydrogenase reductase Sdr
Verru16B_RS06645	COG4948	Mandelate Racemase Muconate Lactonizing
Verru16B_RS06655	COG1879	ABC-type sugar transport system periplasmic component
Verru16B_RS06660	COG1129	ABC transporter
Verru16B_RS06665	COG1172	Belongs to the binding-protein-dependent transport system permease family
Verru16B_RS06690	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Verru16B_RS06710	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
Verru16B_RS06715	COG0590	tRNA wobble adenosine to inosine editing
Verru16B_RS06730	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
Verru16B_RS06735	COG2252	PERMEase
Verru16B_RS06740	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
Verru16B_RS06745	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
Verru16B_RS06760	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
Verru16B_RS06765	COG2233	PERMEase
Verru16B_RS06775	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
Verru16B_RS06780	COG1301	dicarboxylic acid transport
Verru16B_RS06800	COG2211	Major facilitator Superfamily
Verru16B_RS06825	COG4774	siderophore transport
Verru16B_RS06845	COG1472	Belongs to the glycosyl hydrolase 3 family
Verru16B_RS06875	COG1132	(ABC) transporter
Verru16B_RS06890	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Verru16B_RS06895	COG3119	arylsulfatase activity
Verru16B_RS06990	COG1609	Transcriptional regulator
Verru16B_RS07000	COG2211	Major facilitator Superfamily
Verru16B_RS07025	COG1609	Transcriptional regulator
Verru16B_RS07045	COG1301	dicarboxylic acid transport
Verru16B_RS07050	COG1253	flavin adenine dinucleotide binding
Verru16B_RS07055	COG1215	transferase activity, transferring glycosyl groups
Verru16B_RS07070	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
Verru16B_RS07095	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
Verru16B_RS07105	COG0583	DNA-binding transcription factor activity
Verru16B_RS07120	COG0673	inositol 2-dehydrogenase activity
Verru16B_RS07130	COG0577	efflux transmembrane transporter activity
Verru16B_RS07130	COG1136	(ABC) transporter
Verru16B_RS07135	COG1136	(ABC) transporter
Verru16B_RS07155	COG1966	Carbon starvation protein
Verru16B_RS07190	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Verru16B_RS07205	COG2084	Dehydrogenase
Verru16B_RS07220	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
Verru16B_RS07225	COG2860	membrane
Verru16B_RS07240	COG0534	Mate efflux family protein
Verru16B_RS07245	COG1902	pentaerythritol trinitrate reductase activity
Verru16B_RS07260	COG0708	Exodeoxyribonuclease III
Verru16B_RS07270	COG2382	esterase
Verru16B_RS07280	COG1058	Belongs to the CinA family
Verru16B_RS07280	COG1546	Belongs to the CinA family
Verru16B_RS07300	COG2081	HI0933 family
Verru16B_RS07310	COG0861	Integral membrane protein TerC family
Verru16B_RS07320	COG2183	response to ionizing radiation
Verru16B_RS07345	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Verru16B_RS07380	COG4585	Histidine kinase
Verru16B_RS07425	COG4566	intracellular signal transduction
Verru16B_RS07450	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
Verru16B_RS07460	COG0071	Belongs to the small heat shock protein (HSP20) family
Verru16B_RS07470	COG0668	transmembrane transport
Verru16B_RS07475	COG0842	Transport permease protein
Verru16B_RS07480	COG1131	(ABC) transporter
Verru16B_RS07490	COG1309	transcriptional regulator
Verru16B_RS07500	COG0724	RNA recognition motif
Verru16B_RS07580	COG3265	gluconokinase activity
Verru16B_RS07615	COG2226	methyltransferase
Verru16B_RS07620	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Verru16B_RS07625	COG0800	Aldolase
Verru16B_RS07635	COG1414	Transcriptional regulator
Verru16B_RS07645	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
Verru16B_RS07650	COG1028	Short-chain dehydrogenase reductase Sdr
Verru16B_RS07655	COG4677	pectinesterase activity
Verru16B_RS07660	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
Verru16B_RS07665	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
Verru16B_RS07685	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
Verru16B_RS07690	COG0657	acetylesterase activity
Verru16B_RS07700	COG1028	Short-chain dehydrogenase reductase Sdr
Verru16B_RS07710	COG1904	glucuronate isomerase
Verru16B_RS07725	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
Verru16B_RS07730	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Verru16B_RS07740	COG2205	protein histidine kinase activity
Verru16B_RS07740	COG2198	Histidine kinase
Verru16B_RS07740	COG0784	Response regulator, receiver
Verru16B_RS07745	COG3590	peptidase
Verru16B_RS07775	COG3220	belongs to the UPF0276 family
Verru16B_RS07795	COG1162	GTPase activity
Verru16B_RS07820	COG3386	PFAM SMP-30 Gluconolaconase
Verru16B_RS07825	COG1695	Transcriptional regulator
Verru16B_RS07830	COG1136	(ABC) transporter
Verru16B_RS07830	COG0577	efflux transmembrane transporter activity
Verru16B_RS07835	COG4772	TonB-dependent receptor
Verru16B_RS07860	COG0022	dehydrogenase e1 component
Verru16B_RS07865	COG0673	inositol 2-dehydrogenase activity
Verru16B_RS07880	COG0017	Asparaginyl-tRNA synthetase
Verru16B_RS07905	COG2211	Major facilitator Superfamily
Verru16B_RS07915	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
Verru16B_RS07920	COG0799	negative regulation of ribosome biogenesis
Verru16B_RS07965	COG0463	Glycosyl transferase, family 2
Verru16B_RS07985	COG1215	transferase activity, transferring glycosyl groups
Verru16B_RS08040	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Verru16B_RS08045	COG3876	Protein conserved in bacteria
Verru16B_RS08050	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
Verru16B_RS08060	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
Verru16B_RS08070	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Verru16B_RS08085	COG2877	3-deoxy-8-phosphooctulonate synthase activity
Verru16B_RS08090	COG1605	Chorismate mutase
Verru16B_RS08090	COG0077	Prephenate dehydratase
Verru16B_RS08100	COG0297	glycogen (starch) synthase activity
Verru16B_RS08120	COG1172	Belongs to the binding-protein-dependent transport system permease family
Verru16B_RS08125	COG1129	ABC transporter
Verru16B_RS08135	COG0432	Pfam Uncharacterised protein family UPF0047
Verru16B_RS08155	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Verru16B_RS08165	COG3250	beta-galactosidase activity
Verru16B_RS08170	COG0673	inositol 2-dehydrogenase activity
Verru16B_RS08185	COG0724	RNA recognition motif
Verru16B_RS08190	COG4771	TonB-dependent receptor
Verru16B_RS08200	COG2205	protein histidine kinase activity
Verru16B_RS08205	COG1530	ribonuclease E activity
Verru16B_RS08210	COG0772	Belongs to the SEDS family
Verru16B_RS08225	COG1216	Glycosyl transferase, family 2
Verru16B_RS08225	COG0463	Glycosyl transferase, family 2
Verru16B_RS08255	COG1418	mRNA catabolic process
Verru16B_RS08260	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
Verru16B_RS08285	COG0598	Magnesium transport protein CorA
Verru16B_RS08290	COG3591	Belongs to the peptidase S1B family
Verru16B_RS08310	COG0187	DNA topoisomerase II activity
Verru16B_RS08325	COG0268	Binds directly to 16S ribosomal RNA
Verru16B_RS08330	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
Verru16B_RS08340	COG1074	ATP-dependent DNA helicase activity
Verru16B_RS08375	COG0142	geranyltranstransferase activity
Verru16B_RS08390	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
Verru16B_RS08390	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
Verru16B_RS08400	COG2823	Periplasmic or secreted lipoprotein
Verru16B_RS08400	COG1652	LysM domain
Verru16B_RS08405	COG0720	synthase
Verru16B_RS08410	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Verru16B_RS08420	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Verru16B_RS08425	COG0822	iron-sulfur transferase activity
Verru16B_RS08435	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Verru16B_RS08445	COG0649	NAD binding
Verru16B_RS08480	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Verru16B_RS08485	COG0839	Belongs to the complex I subunit 6 family
Verru16B_RS08490	COG0713	ATP synthesis coupled electron transport
Verru16B_RS08495	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Verru16B_RS08500	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Verru16B_RS08505	COG1007	ATP synthesis coupled electron transport
Verru16B_RS08540	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Verru16B_RS08540	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Verru16B_RS08545	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
Verru16B_RS08550	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Verru16B_RS08555	COG0552	protein localization to endoplasmic reticulum
Verru16B_RS08570	COG4773	Receptor
Verru16B_RS08580	COG4774	siderophore transport
Verru16B_RS08585	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
Verru16B_RS08595	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Verru16B_RS08600	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
Verru16B_RS08605	COG1404	Belongs to the peptidase S8 family
Verru16B_RS08615	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
Verru16B_RS08620	COG0860	N-Acetylmuramoyl-L-alanine amidase
Verru16B_RS08630	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Verru16B_RS08645	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
Verru16B_RS08655	COG0129	dihydroxy-acid dehydratase activity
Verru16B_RS08660	COG0179	Fumarylacetoacetate (FAA) hydrolase
Verru16B_RS08680	COG2151	metal-sulfur cluster biosynthetic enzyme
Verru16B_RS08690	COG0719	Fe-S assembly protein
Verru16B_RS08695	COG0719	Fe-S assembly protein
Verru16B_RS08700	COG0396	ATPase activity
Verru16B_RS08710	COG0840	transmembrane signaling receptor activity
Verru16B_RS08730	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Verru16B_RS08745	COG1032	radical SAM domain protein
Verru16B_RS08770	COG0456	acetyltransferase
Verru16B_RS08785	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Verru16B_RS08855	COG0210	DNA helicase
Verru16B_RS08865	COG1943	Transposase
Verru16B_RS08885	COG0528	UMP kinase activity
Verru16B_RS08905	COG0363	glucosamine-6-phosphate deaminase activity
Verru16B_RS08915	COG2827	Endonuclease containing a URI domain
Verru16B_RS08950	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
Verru16B_RS08955	COG3012	SEC-C Motif Domain Protein
Verru16B_RS08965	COG3275	phosphorelay sensor kinase activity
Verru16B_RS08970	COG3279	Response regulator of the LytR AlgR family
Verru16B_RS09020	COG2827	Endonuclease containing a URI domain
Verru16B_RS09030	COG2068	MobA-Related Protein
Verru16B_RS09035	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
Verru16B_RS09040	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Verru16B_RS09050	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Verru16B_RS09060	COG0521	Mo-molybdopterin cofactor biosynthetic process
Verru16B_RS09065	COG0315	cyclic pyranopterin monophosphate synthase activity
Verru16B_RS09065	COG0521	Mo-molybdopterin cofactor biosynthetic process
Verru16B_RS09105	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Verru16B_RS09110	COG4585	Histidine kinase
Verru16B_RS09115	COG2197	response regulator
Verru16B_RS09130	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
Verru16B_RS09135	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
Verru16B_RS09140	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
Verru16B_RS09150	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
Verru16B_RS09155	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
Verru16B_RS09175	COG0154	amidase activity
Verru16B_RS09190	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
Verru16B_RS09205	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Verru16B_RS09215	COG1609	Transcriptional regulator
Verru16B_RS09220	COG4774	siderophore transport
Verru16B_RS09225	COG1007	ATP synthesis coupled electron transport
Verru16B_RS09230	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Verru16B_RS09245	COG0713	ATP synthesis coupled electron transport
Verru16B_RS09265	COG0649	NAD binding
Verru16B_RS09270	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Verru16B_RS09275	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Verru16B_RS09280	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Verru16B_RS09290	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Verru16B_RS09295	COG0346	lactoylglutathione lyase activity
Verru16B_RS09325	COG2304	oxidoreductase activity
Verru16B_RS09345	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
Verru16B_RS09385	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Verru16B_RS09405	COG2304	oxidoreductase activity
Verru16B_RS09420	COG0714	Associated with various cellular activities
Verru16B_RS09425	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
Verru16B_RS09445	COG1322	Protein conserved in bacteria
Verru16B_RS09460	COG3852	Histidine kinase
Verru16B_RS09495	COG1554	hydrolase, family 65, central catalytic
Verru16B_RS09510	COG1131	(ABC) transporter
Verru16B_RS09525	COG3642	lipopolysaccharide core region biosynthetic process
Verru16B_RS09550	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
Verru16B_RS09565	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Verru16B_RS09565	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Verru16B_RS09570	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Verru16B_RS09570	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Verru16B_RS09580	COG0346	lactoylglutathione lyase activity
Verru16B_RS09660	COG1185	polyribonucleotide nucleotidyltransferase activity
Verru16B_RS09665	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
Verru16B_RS09680	COG1132	(ABC) transporter
Verru16B_RS09685	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Verru16B_RS09690	COG0601	transmembrane transport
Verru16B_RS09695	COG4166	transmembrane transport
Verru16B_RS09705	COG4166	transmembrane transport
Verru16B_RS09710	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
Verru16B_RS09715	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
Verru16B_RS09720	COG0284	orotidine-5'-phosphate decarboxylase activity
Verru16B_RS09725	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
Verru16B_RS09730	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Verru16B_RS09745	COG2226	methyltransferase
Verru16B_RS09775	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Verru16B_RS09780	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Verru16B_RS09790	COG0151	Belongs to the GarS family
Verru16B_RS09810	COG0545	Peptidyl-prolyl cis-trans isomerase
Verru16B_RS09815	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
Verru16B_RS09820	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
Verru16B_RS09835	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Verru16B_RS09840	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Verru16B_RS09845	COG0300	oxidoreductase activity
Verru16B_RS09860	COG0066	3-isopropylmalate dehydratase activity
Verru16B_RS09865	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Verru16B_RS09870	COG0583	DNA-binding transcription factor activity
Verru16B_RS09910	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Verru16B_RS09925	COG1215	transferase activity, transferring glycosyl groups
Verru16B_RS09935	COG3510	cephalosporin hydroxylase
Verru16B_RS09940	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
Verru16B_RS09960	COG1216	Glycosyl transferase, family 2
Verru16B_RS10000	COG2226	methyltransferase
Verru16B_RS10005	COG4206	TonB-dependent receptor
Verru16B_RS10070	COG0438	transferase activity, transferring glycosyl groups
Verru16B_RS10080	COG0438	transferase activity, transferring glycosyl groups
Verru16B_RS10090	COG0438	transferase activity, transferring glycosyl groups
Verru16B_RS10090	COG1216	Glycosyl transferase, family 2
Verru16B_RS10120	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Verru16B_RS10120	COG2813	Specifically methylates the guanine in position
Verru16B_RS10125	COG0463	Glycosyl transferase, family 2
Verru16B_RS10130	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Verru16B_RS10150	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Verru16B_RS10160	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Verru16B_RS10165	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
Verru16B_RS10170	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Verru16B_RS10180	COG0107	imidazoleglycerol-phosphate synthase activity
Verru16B_RS10190	COG1083	cytidylyl-transferase
Verru16B_RS10215	COG1086	Polysaccharide biosynthesis protein
Verru16B_RS10240	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Verru16B_RS10250	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Verru16B_RS10250	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Verru16B_RS10265	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
Verru16B_RS10275	COG1086	Polysaccharide biosynthesis protein
Verru16B_RS10290	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Verru16B_RS10295	COG4591	ABC-type transport system involved in lipoprotein release permease component
Verru16B_RS10300	COG1136	(ABC) transporter
Verru16B_RS10310	COG0437	4 iron, 4 sulfur cluster binding
Verru16B_RS10325	COG2010	Cytochrome c
Verru16B_RS10350	COG2010	Cytochrome c
Verru16B_RS10360	COG0824	Thioesterase
Verru16B_RS10390	COG4181	ATPase activity
Verru16B_RS10395	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
Verru16B_RS10400	COG1047	Peptidyl-prolyl cis-trans
Verru16B_RS10415	COG1136	(ABC) transporter
Verru16B_RS10420	COG0577	efflux transmembrane transporter activity
Verru16B_RS10420	COG1136	(ABC) transporter
Verru16B_RS10435	COG0563	adenylate kinase activity
Verru16B_RS10440	COG0826	peptidase U32
Verru16B_RS10455	COG1595	DNA-templated transcription, initiation
Verru16B_RS10480	COG1193	negative regulation of DNA recombination
Verru16B_RS10490	COG1131	(ABC) transporter
Verru16B_RS10500	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Verru16B_RS10510	COG1030	water channel activity
Verru16B_RS10520	COG4864	UPF0365 protein
Verru16B_RS10530	COG1426	Protein conserved in bacteria
Verru16B_RS10535	COG1674	ftsk spoiiie
Verru16B_RS10540	COG1482	cell wall glycoprotein biosynthetic process
Verru16B_RS10545	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Verru16B_RS10550	COG0484	heat shock protein binding
Verru16B_RS10560	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
Verru16B_RS10565	COG2264	protein methyltransferase activity
Verru16B_RS10575	COG0511	ligase activity, forming carbon-carbon bonds
Verru16B_RS10685	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
Verru16B_RS10700	COG1516	flagellar protein fliS
Verru16B_RS10715	COG2204	response regulator
Verru16B_RS10730	COG4191	Histidine kinase
Verru16B_RS10730	COG0784	Response regulator, receiver
Verru16B_RS10735	COG0835	chemotaxis
Verru16B_RS10740	COG2198	Histidine kinase
Verru16B_RS10740	COG0643	Histidine kinase
Verru16B_RS10750	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
Verru16B_RS10775	COG2201	protein-glutamate methylesterase activity
Verru16B_RS10785	COG1815	bacterial-type flagellum-dependent cell motility
Verru16B_RS10795	COG1677	Flagellar hook-basal body complex protein FliE
Verru16B_RS10800	COG1766	The M ring may be actively involved in energy transduction
Verru16B_RS10805	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Verru16B_RS10820	COG1157	protein secretion by the type III secretion system
Verru16B_RS10845	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
Verru16B_RS10850	COG4786	Flagellar basal body rod
Verru16B_RS10860	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Verru16B_RS10865	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Verru16B_RS10865	COG1776	CheC inhibitor of MCP methylation
Verru16B_RS10875	COG3190	flagellar
Verru16B_RS10875	COG1338	Plays a role in the flagellum-specific transport system
Verru16B_RS10880	COG1987	bacterial-type flagellum assembly
Verru16B_RS10890	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Verru16B_RS10895	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Verru16B_RS10910	COG1191	sigma factor activity
Verru16B_RS10930	COG4786	Flagellar basal body rod
Verru16B_RS10935	COG4786	Flagellar basal body rod
Verru16B_RS10945	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
Verru16B_RS10950	COG1706	bacterial-type flagellum-dependent cell motility
Verru16B_RS10975	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
Verru16B_RS10980	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
Verru16B_RS10985	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Verru16B_RS11000	COG0840	transmembrane signaling receptor activity
Verru16B_RS11025	COG0456	acetyltransferase
Verru16B_RS11035	COG0482	sulfurtransferase activity
Verru16B_RS11040	COG1523	belongs to the glycosyl hydrolase 13 family
Verru16B_RS11045	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
Verru16B_RS11050	COG0126	phosphoglycerate kinase activity
Verru16B_RS11055	COG0149	triose-phosphate isomerase activity
Verru16B_RS11070	COG0142	geranyltranstransferase activity
Verru16B_RS11085	COG0728	peptidoglycan biosynthetic process
Verru16B_RS11100	COG0227	Belongs to the bacterial ribosomal protein bL28 family
Verru16B_RS11110	COG0793	Belongs to the peptidase S41A family
Verru16B_RS11115	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
Verru16B_RS11125	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Verru16B_RS11135	COG1950	PFAM Membrane protein of
Verru16B_RS11140	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Verru16B_RS11145	COG0673	inositol 2-dehydrogenase activity
Verru16B_RS11155	COG2814	Major facilitator Superfamily
Verru16B_RS11180	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
Verru16B_RS11190	COG1187	pseudouridine synthase activity
Verru16B_RS11195	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
Verru16B_RS11200	COG1028	Short-chain dehydrogenase reductase Sdr
Verru16B_RS11205	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Verru16B_RS11210	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Verru16B_RS11230	COG2204	response regulator
Verru16B_RS11250	COG0525	valine-tRNA ligase activity
Verru16B_RS11255	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
Verru16B_RS11260	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Verru16B_RS11270	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
Verru16B_RS11305	COG0475	glutathione-regulated potassium exporter activity
Verru16B_RS11310	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Verru16B_RS11320	COG0358	DNA primase activity
Verru16B_RS11350	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Verru16B_RS11380	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Verru16B_RS11390	COG0438	transferase activity, transferring glycosyl groups
Verru16B_RS11395	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Verru16B_RS11400	COG0038	chloride channel
Verru16B_RS11415	COG0573	inorganic phosphate transmembrane transporter activity
Verru16B_RS11435	COG1940	carbohydrate kinase activity
Verru16B_RS11460	COG0159	tryptophan synthase activity
Verru16B_RS11470	COG1597	lipid kinase activity
Verru16B_RS11475	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
Verru16B_RS11510	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
Verru16B_RS11515	COG0045	succinate-CoA ligase (ADP-forming) activity
Verru16B_RS11555	COG0831	urea catabolic process
Verru16B_RS11560	COG0832	Belongs to the urease beta subunit family
Verru16B_RS11565	COG0804	urea catabolic process
Verru16B_RS11580	COG0830	nickel cation binding
Verru16B_RS11585	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
Verru16B_RS11590	COG0829	nickel cation binding
Verru16B_RS11600	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
Verru16B_RS11610	COG1137	ATPase activity
Verru16B_RS11630	COG0400	carboxylic ester hydrolase activity
Verru16B_RS11635	COG0346	lactoylglutathione lyase activity
Verru16B_RS11640	COG1846	Transcriptional regulator
Verru16B_RS11645	COG0698	ribose 5-phosphate isomerase
Verru16B_RS11675	COG0508	dehydrogenase complex catalyzes the overall conversion of
Verru16B_RS11680	COG0567	Dehydrogenase, E1 component
Verru16B_RS11690	COG0023	Translation Initiation Factor
Verru16B_RS11695	COG0673	inositol 2-dehydrogenase activity
Verru16B_RS11700	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
Verru16B_RS11705	COG0820	rRNA (adenine-C2-)-methyltransferase activity
Verru16B_RS11710	COG0795	lipopolysaccharide-transporting ATPase activity
Verru16B_RS11735	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
Verru16B_RS11750	COG0631	protein serine/threonine phosphatase activity
Verru16B_RS11760	COG0174	glutamine synthetase
Verru16B_RS11780	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
Verru16B_RS11785	COG0590	tRNA wobble adenosine to inosine editing
Verru16B_RS11790	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
Verru16B_RS11795	COG4974	Belongs to the 'phage' integrase family
Verru16B_RS11810	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
Verru16B_RS11815	COG1028	Short-chain dehydrogenase reductase Sdr
Verru16B_RS11835	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
Verru16B_RS11855	COG0534	Mate efflux family protein
Verru16B_RS11895	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
Verru16B_RS11900	COG0513	Belongs to the DEAD box helicase family
Verru16B_RS11905	COG0531	amino acid
Verru16B_RS11915	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Verru16B_RS11930	COG3852	Histidine kinase
Verru16B_RS11935	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
Verru16B_RS11945	COG1028	Short-chain dehydrogenase reductase Sdr
Verru16B_RS11955	COG0180	Tryptophanyl-tRNA synthetase
Verru16B_RS11970	COG0204	Acyl-transferase
Verru16B_RS11975	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
Verru16B_RS11980	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
Verru16B_RS11985	COG0287	Prephenate dehydrogenase
Verru16B_RS11995	COG4956	integral membrane protein (PIN domain superfamily)
Verru16B_RS12005	COG1131	(ABC) transporter
Verru16B_RS12035	COG1702	phosphate starvation-inducible protein PhoH
Verru16B_RS12045	COG3647	Membrane
Verru16B_RS12065	COG2205	protein histidine kinase activity
Verru16B_RS12065	COG4999	Histidine kinase
Verru16B_RS12065	COG3850	Histidine kinase
Verru16B_RS12065	COG3437	response regulator, receiver
Verru16B_RS12085	COG0745	RESPONSE REGULATOR receiver
Verru16B_RS12115	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
Verru16B_RS12120	COG1136	(ABC) transporter
Verru16B_RS12120	COG0577	efflux transmembrane transporter activity
Verru16B_RS12125	COG4335	DNA alkylation repair
Verru16B_RS12130	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Verru16B_RS12150	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
Verru16B_RS12175	COG2197	response regulator
Verru16B_RS12185	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Verru16B_RS12185	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Verru16B_RS12195	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
Verru16B_RS12200	COG4191	Histidine kinase
Verru16B_RS12205	COG3158	transport of potassium into the cell
Verru16B_RS12210	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
Verru16B_RS12215	COG3361	conserved protein (COG2071)
Verru16B_RS12230	COG4172	Belongs to the ABC transporter superfamily
Verru16B_RS12235	COG1560	Kdo2-lipid A biosynthetic process
Verru16B_RS12240	COG0859	PFAM glycosyl transferase family 9
Verru16B_RS12255	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
Verru16B_RS12260	COG0037	tRNA processing
Verru16B_RS12265	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Verru16B_RS12270	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
Verru16B_RS12280	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Verru16B_RS12290	COG0544	peptidyl-prolyl cis-trans isomerase activity
Verru16B_RS12295	COG0740	serine-type endopeptidase activity
Verru16B_RS12300	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
Verru16B_RS12305	COG1363	Peptidase, m42
Verru16B_RS12320	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
Verru16B_RS12335	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Verru16B_RS12340	COG0416	fatty acid biosynthetic process
Verru16B_RS12345	COG0333	Belongs to the bacterial ribosomal protein bL32 family
Verru16B_RS12350	COG1968	undecaprenyl-diphosphatase activity
Verru16B_RS12355	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Verru16B_RS12360	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Verru16B_RS12375	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
Verru16B_RS12390	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
Verru16B_RS12400	COG2211	Major facilitator Superfamily
Verru16B_RS12405	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
Verru16B_RS12410	COG0347	Belongs to the P(II) protein family
Verru16B_RS12425	COG3938	Belongs to the proline racemase family
Verru16B_RS12430	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Verru16B_RS12455	COG1490	D-aminoacyl-tRNA deacylase activity
Verru16B_RS12460	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
Verru16B_RS12525	COG0673	inositol 2-dehydrogenase activity
Verru16B_RS12530	COG0673	inositol 2-dehydrogenase activity
Verru16B_RS12630	COG2080	2 iron, 2 sulfur cluster binding
Verru16B_RS12635	COG2010	Cytochrome c
Verru16B_RS12635	COG1529	Aldehyde oxidase and xanthine dehydrogenase
Verru16B_RS12655	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
Verru16B_RS12670	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
Verru16B_RS12680	COG0586	Pfam SNARE associated Golgi protein
Verru16B_RS12690	COG1758	RNA polymerase activity
Verru16B_RS12695	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
Verru16B_RS12700	COG0083	homoserine kinase activity
Verru16B_RS12705	COG2204	response regulator
Verru16B_RS12710	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
Verru16B_RS12715	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
Verru16B_RS12720	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Verru16B_RS12740	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
Verru16B_RS12755	COG1678	Uncharacterized ACR, COG1678
Verru16B_RS12760	COG0257	Belongs to the bacterial ribosomal protein bL36 family
Verru16B_RS12765	COG0254	rRNA binding
Verru16B_RS12770	COG0560	Phosphoserine phosphatase
Verru16B_RS12785	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Verru16B_RS12790	COG0556	nucleotide-excision repair
Verru16B_RS12805	COG1254	Belongs to the acylphosphatase family
Verru16B_RS12810	COG1131	(ABC) transporter
Verru16B_RS12835	COG1575	Belongs to the MenA family. Type 1 subfamily
Verru16B_RS12840	COG3118	belongs to the thioredoxin family
Verru16B_RS12850	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
Verru16B_RS12870	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
Verru16B_RS12875	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Verru16B_RS12880	COG2198	Histidine kinase
Verru16B_RS12880	COG5002	protein histidine kinase activity
Verru16B_RS12880	COG0784	Response regulator, receiver
Verru16B_RS12885	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Verru16B_RS12890	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Verru16B_RS12900	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
Verru16B_RS12905	COG0101	tRNA pseudouridine synthase activity
Verru16B_RS12910	COG1040	competence protein
Verru16B_RS12915	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
Verru16B_RS12940	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Verru16B_RS12945	COG0577	efflux transmembrane transporter activity
Verru16B_RS12945	COG1136	(ABC) transporter
Verru16B_RS12960	COG4591	ABC-type transport system involved in lipoprotein release permease component
Verru16B_RS12960	COG1136	(ABC) transporter
Verru16B_RS12975	COG4191	Histidine kinase
Verru16B_RS12990	COG0577	efflux transmembrane transporter activity
Verru16B_RS12990	COG1136	(ABC) transporter
Verru16B_RS12995	COG1136	(ABC) transporter
Verru16B_RS12995	COG0577	efflux transmembrane transporter activity
Verru16B_RS13015	COG3409	Peptidoglycan-binding domain 1 protein
Verru16B_RS13015	COG3267	Type II secretory pathway component ExeA
Verru16B_RS13025	COG4284	Utp--glucose-1-phosphate uridylyltransferase
Verru16B_RS13030	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Verru16B_RS13050	COG0022	dehydrogenase e1 component
Verru16B_RS13055	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
Verru16B_RS13090	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Verru16B_RS13100	COG0745	RESPONSE REGULATOR receiver
Verru16B_RS13105	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Verru16B_RS13105	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
Verru16B_RS13110	COG2957	Belongs to the agmatine deiminase family
Verru16B_RS13120	COG0539	negative regulation of cytoplasmic translation
Verru16B_RS13120	COG2183	response to ionizing radiation
Verru16B_RS13125	COG3345	alpha-galactosidase
Verru16B_RS13130	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Verru16B_RS13140	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Verru16B_RS13145	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
Verru16B_RS13150	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
Verru16B_RS13160	COG0509	glycine decarboxylation via glycine cleavage system
Verru16B_RS13170	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Verru16B_RS13180	COG1217	gtp-binding protein TYPA
Verru16B_RS13205	COG1643	Atp-dependent helicase
Verru16B_RS13215	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
Verru16B_RS13220	COG3250	beta-galactosidase activity
Verru16B_RS13225	COG1166	arginine decarboxylase activity
Verru16B_RS13230	COG1862	Preprotein translocase
Verru16B_RS13235	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Verru16B_RS13235	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Verru16B_RS13240	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
Verru16B_RS13240	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
Verru16B_RS13245	COG0586	Pfam SNARE associated Golgi protein
Verru16B_RS13255	COG1331	Highly conserved protein containing a thioredoxin domain
Verru16B_RS13270	COG1262	PFAM Formylglycine-generating sulfatase enzyme
Verru16B_RS13275	COG1262	PFAM Formylglycine-generating sulfatase enzyme
Verru16B_RS13310	COG0564	pseudouridine synthase activity
Verru16B_RS13320	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Verru16B_RS13330	COG2201	protein-glutamate methylesterase activity
Verru16B_RS13335	COG0745	RESPONSE REGULATOR receiver
Verru16B_RS13350	COG0643	Histidine kinase
Verru16B_RS13350	COG2198	Histidine kinase
Verru16B_RS13350	COG0784	Response regulator, receiver
Verru16B_RS13355	COG0745	RESPONSE REGULATOR receiver
Verru16B_RS13375	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Verru16B_RS13390	COG2165	general secretion pathway protein
Verru16B_RS13400	COG3880	PFAM UvrB UvrC protein
Verru16B_RS13405	COG3869	Catalyzes the specific phosphorylation of arginine residues in
Verru16B_RS13410	COG0542	response to heat
Verru16B_RS13420	COG0811	peptide transport
Verru16B_RS13440	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Verru16B_RS13445	COG0215	cysteine-tRNA ligase activity
Verru16B_RS13450	COG0113	porphobilinogen synthase activity
Verru16B_RS13455	COG0673	inositol 2-dehydrogenase activity
Verru16B_RS13460	COG0531	amino acid
Verru16B_RS13475	COG0167	dihydroorotate dehydrogenase activity
Verru16B_RS13480	COG1045	serine acetyltransferase
Verru16B_RS13500	COG0802	atpase or kinase
Verru16B_RS13505	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
Verru16B_RS13515	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Verru16B_RS13525	COG0267	Belongs to the bacterial ribosomal protein bL33 family
Verru16B_RS13535	COG0489	protein tyrosine kinase activity
Verru16B_RS13545	COG1692	metallophosphoesterase
Verru16B_RS13565	COG0165	Argininosuccinate lyase
Verru16B_RS13575	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
Verru16B_RS13575	COG3170	Tfp pilus assembly protein FimV
Verru16B_RS13580	COG0058	SHG alpha-glucan phosphorylase activity
Verru16B_RS13640	COG0232	Belongs to the dGTPase family. Type 2 subfamily
Verru16B_RS13650	COG3250	beta-galactosidase activity
Verru16B_RS13665	COG1505	serine-type exopeptidase activity
Verru16B_RS13670	COG1902	pentaerythritol trinitrate reductase activity
Verru16B_RS13675	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Verru16B_RS13680	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
Verru16B_RS13685	COG0527	aspartate kinase activity
Verru16B_RS13700	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Verru16B_RS13710	COG2003	Belongs to the UPF0758 family
Verru16B_RS13715	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Verru16B_RS13750	COG3940	Belongs to the glycosyl hydrolase 43 family
Verru16B_RS13750	COG3940	Belongs to the glycosyl hydrolase 43 family
Verru16B_RS13760	COG2814	Major facilitator Superfamily
Verru16B_RS13765	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Verru16B_RS13780	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Verru16B_RS13780	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Verru16B_RS13790	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
Verru16B_RS13810	COG0730	response to heat
Verru16B_RS13820	COG0577	efflux transmembrane transporter activity
Verru16B_RS13820	COG1136	(ABC) transporter
Verru16B_RS13865	COG2080	2 iron, 2 sulfur cluster binding
Verru16B_RS13870	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Verru16B_RS13890	COG0583	DNA-binding transcription factor activity
Verru16B_RS13895	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Verru16B_RS13905	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Verru16B_RS13925	COG0297	glycogen (starch) synthase activity
Verru16B_RS13930	COG0110	maltose O-acetyltransferase activity
Verru16B_RS14000	COG1215	transferase activity, transferring glycosyl groups
Verru16B_RS14005	COG0297	glycogen (starch) synthase activity
Verru16B_RS14055	COG0367	asparagine synthase
Verru16B_RS14070	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
Verru16B_RS14075	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
Verru16B_RS14090	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Verru16B_RS14095	COG1722	exodeoxyribonuclease VII activity
Verru16B_RS14100	COG0501	Belongs to the peptidase M48B family
Verru16B_RS14135	COG1595	DNA-templated transcription, initiation
Verru16B_RS14140	COG2309	aminopeptidase activity
Verru16B_RS14155	COG0191	fructose-bisphosphate aldolase activity
Verru16B_RS14160	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Verru16B_RS14160	COG0551	DNA topoisomerase type I activity
Verru16B_RS14170	COG1663	tetraacyldisaccharide 4'-kinase activity
Verru16B_RS14180	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
Verru16B_RS14195	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Verru16B_RS14200	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Verru16B_RS14260	COG0443	Heat shock 70 kDa protein
Verru16B_RS14265	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
Verru16B_RS14265	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Verru16B_RS14275	COG0442	prolyl-tRNA aminoacylation
Verru16B_RS14280	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
Verru16B_RS14325	COG4948	Mandelate Racemase Muconate Lactonizing
Verru16B_RS14330	COG0318	PFAM AMP-dependent synthetase and ligase
Verru16B_RS14335	COG1796	DNA polymerase
Verru16B_RS14335	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
Verru16B_RS14355	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Verru16B_RS14360	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
Verru16B_RS14360	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Verru16B_RS14365	COG0424	maF-like protein
Verru16B_RS14375	COG0564	pseudouridine synthase activity
Verru16B_RS14380	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
Verru16B_RS14385	COG2267	carboxylic ester hydrolase activity
Verru16B_RS14390	COG0534	Mate efflux family protein
Verru16B_RS14400	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
Verru16B_RS14405	COG0811	peptide transport
Verru16B_RS14425	COG1994	Peptidase M50
Verru16B_RS14435	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Verru16B_RS14440	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Verru16B_RS14445	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Verru16B_RS14450	COG1233	COG1233 Phytoene dehydrogenase and related
Verru16B_RS14465	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Verru16B_RS14475	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Verru16B_RS14480	COG0596	Alpha beta hydrolase
Verru16B_RS14485	COG0681	Belongs to the peptidase S26 family
Verru16B_RS14490	COG0481	GTPase activity
Verru16B_RS14510	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Verru16B_RS14515	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
Verru16B_RS14520	COG0632	four-way junction helicase activity
Verru16B_RS14540	COG2197	response regulator
Verru16B_RS14545	COG2885	chlorophyll binding
Verru16B_RS14560	COG4783	chaperone-mediated protein folding
Verru16B_RS14570	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Verru16B_RS14575	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Verru16B_RS14580	COG1121	(ABC) transporter
Verru16B_RS14585	COG0803	Belongs to the bacterial solute-binding protein 9 family
Verru16B_RS14605	COG0697	spore germination
Verru16B_RS14620	COG4628	conserved protein (DUF2132)
Verru16B_RS14635	COG0408	coproporphyrinogen oxidase activity
Verru16B_RS14640	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
Verru16B_RS14645	COG1233	COG1233 Phytoene dehydrogenase and related
Verru16B_RS14650	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
Verru16B_RS14655	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
Verru16B_RS14660	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
Verru16B_RS14665	COG1561	YicC-like family, N-terminal region
Verru16B_RS14670	COG0133	tryptophan synthase activity
Verru16B_RS14685	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
Verru16B_RS14700	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
Verru16B_RS14765	COG2731	YhcH YjgK YiaL family protein
Verru16B_RS14770	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Verru16B_RS14780	COG1510	regulation of RNA biosynthetic process
Verru16B_RS14805	COG2197	response regulator
Verru16B_RS14810	COG4974	Belongs to the 'phage' integrase family
Verru16B_RS14815	COG3956	TIGRFAM MazG family protein
Verru16B_RS14820	COG0134	indole-3-glycerol-phosphate synthase activity
Verru16B_RS14825	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
Verru16B_RS14860	COG0673	inositol 2-dehydrogenase activity
Verru16B_RS14870	COG0673	inositol 2-dehydrogenase activity
Verru16B_RS14910	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Verru16B_RS14920	COG0300	oxidoreductase activity
Verru16B_RS14935	COG0673	inositol 2-dehydrogenase activity
Verru16B_RS14945	COG1994	Peptidase M50
Verru16B_RS14945	COG0517	IMP dehydrogenase activity
Verru16B_RS14965	COG0741	lytic transglycosylase activity
Verru16B_RS15000	COG4771	TonB-dependent receptor
Verru16B_RS15125	COG2226	methyltransferase
Verru16B_RS15130	COG1879	ABC-type sugar transport system periplasmic component
Verru16B_RS15175	COG2824	Alkylphosphonate utilization operon protein PhnA
Verru16B_RS15220	COG4941	Belongs to the sigma-70 factor family
Verru16B_RS15255	COG1475	DNA binding
Verru16B_RS15265	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Verru16B_RS15275	COG0745	RESPONSE REGULATOR receiver
Verru16B_RS15280	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Verru16B_RS15310	COG0181	hydroxymethylbilane synthase activity
Verru16B_RS15320	COG0564	pseudouridine synthase activity
Verru16B_RS15325	COG0138	bifunctional purine biosynthesis protein purh
Verru16B_RS15335	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
Verru16B_RS15340	COG1218	3'(2'),5'-bisphosphate nucleotidase
Verru16B_RS15345	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Verru16B_RS15365	COG0343	queuine tRNA-ribosyltransferase activity
Verru16B_RS15370	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Verru16B_RS15400	COG1136	(ABC) transporter
Verru16B_RS15400	COG0577	efflux transmembrane transporter activity
Verru16B_RS15415	COG0628	permease
Verru16B_RS15425	COG1793	dna ligase
Verru16B_RS15425	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
Verru16B_RS15435	COG2094	Belongs to the DNA glycosylase MPG family
Verru16B_RS15440	COG0261	This protein binds to 23S rRNA in the presence of protein L20
Verru16B_RS15445	COG0211	Belongs to the bacterial ribosomal protein bL27 family
Verru16B_RS15455	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
Verru16B_RS15460	COG0166	Belongs to the GPI family
Verru16B_RS15465	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
Verru16B_RS15470	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
Verru16B_RS15470	COG0248	Ppx GppA phosphatase
Verru16B_RS15475	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
Verru16B_RS15490	COG2217	Heavy metal translocating P-type atpase
Verru16B_RS15495	COG1199	ATP-dependent helicase activity
Verru16B_RS15500	COG0631	protein serine/threonine phosphatase activity
Verru16B_RS15550	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Verru16B_RS15565	COG2326	polyphosphate kinase activity
Verru16B_RS15595	COG2208	phosphoserine phosphatase activity
Verru16B_RS15615	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
Verru16B_RS15620	COG3481	metal-dependent phosphohydrolase, HD sub domain
Verru16B_RS15625	COG1459	type II secretion system
Verru16B_RS15630	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Verru16B_RS15640	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Verru16B_RS15645	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
Verru16B_RS15650	COG0237	dephospho-CoA kinase activity
Verru16B_RS15660	COG0606	chelatase, subunit chli
Verru16B_RS15670	COG1054	Belongs to the UPF0176 family
Verru16B_RS15680	COG0513	Belongs to the DEAD box helicase family
Verru16B_RS15790	COG0514	ATP-dependent DNA helicase (RecQ)
Verru16B_RS15795	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Verru16B_RS15805	COG0602	queuosine metabolic process
Verru16B_RS15855	COG0494	nUDIX hydrolase
Verru16B_RS15925	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
Verru16B_RS15925	COG0028	Belongs to the TPP enzyme family
Verru16B_RS15935	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Verru16B_RS15985	COG3842	ATPase activity
Verru16B_RS16005	COG0105	UTP biosynthetic process
Verru16B_RS16010	COG3046	protein related to deoxyribodipyrimidine photolyase
Verru16B_RS16015	COG0415	Belongs to the DNA photolyase family
Verru16B_RS16020	COG0297	glycogen (starch) synthase activity
Verru16B_RS16025	COG0557	exoribonuclease II activity
Verru16B_RS16030	COG0517	IMP dehydrogenase activity
Verru16B_RS16030	COG0516	GMP reductase activity
Verru16B_RS16065	COG0659	secondary active sulfate transmembrane transporter activity
Verru16B_RS16075	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
Verru16B_RS16095	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
Verru16B_RS16100	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Verru16B_RS16105	COG0583	DNA-binding transcription factor activity
Verru16B_RS16110	COG1116	anion transmembrane transporter activity
Verru16B_RS16110	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Verru16B_RS16115	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Verru16B_RS16130	COG1116	anion transmembrane transporter activity
Verru16B_RS16135	COG1116	anion transmembrane transporter activity
Verru16B_RS16145	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Verru16B_RS16150	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
Verru16B_RS16155	COG0437	4 iron, 4 sulfur cluster binding
Verru16B_RS16160	COG0243	molybdopterin cofactor binding
Verru16B_RS16170	COG0746	molybdenum cofactor guanylyltransferase activity
Verru16B_RS16180	COG0686	Belongs to the AlaDH PNT family
Verru16B_RS16185	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
Verru16B_RS16200	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
Verru16B_RS16210	COG0577	efflux transmembrane transporter activity
Verru16B_RS16210	COG1136	(ABC) transporter
Verru16B_RS16215	COG1136	(ABC) transporter
Verru16B_RS16215	COG0577	efflux transmembrane transporter activity
Verru16B_RS16220	COG0577	efflux transmembrane transporter activity
Verru16B_RS16220	COG1136	(ABC) transporter
Verru16B_RS16225	COG0577	efflux transmembrane transporter activity
Verru16B_RS16225	COG1136	(ABC) transporter
Verru16B_RS16230	COG1136	(ABC) transporter
Verru16B_RS16230	COG0577	efflux transmembrane transporter activity
Verru16B_RS16255	COG0463	Glycosyl transferase, family 2
Verru16B_RS16265	COG0577	efflux transmembrane transporter activity
Verru16B_RS16265	COG1136	(ABC) transporter
Verru16B_RS16280	COG2271	Major facilitator Superfamily
Verru16B_RS16290	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
Verru16B_RS16295	COG0792	nuclease activity
Verru16B_RS16300	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Verru16B_RS16320	COG1196	nuclear chromosome segregation
Verru16B_RS16335	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
Verru16B_RS16340	COG0277	FAD linked oxidase domain protein
Verru16B_RS16345	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Verru16B_RS16350	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
Verru16B_RS16355	COG2814	Major facilitator Superfamily
Verru16B_RS16360	COG0204	Acyl-transferase
Verru16B_RS16360	COG0318	PFAM AMP-dependent synthetase and ligase
Verru16B_RS16370	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
Verru16B_RS16380	COG1176	ABC-type spermidine putrescine transport system, permease component I
Verru16B_RS16385	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
Verru16B_RS16390	COG1177	transmembrane transport
Verru16B_RS16395	COG0667	Aldo Keto reductase
Verru16B_RS16410	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Verru16B_RS16415	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Verru16B_RS16420	COG1846	Transcriptional regulator
Verru16B_RS16430	COG0335	large ribosomal subunit rRNA binding
Verru16B_RS16435	COG0336	Belongs to the RNA methyltransferase TrmD family
Verru16B_RS16440	COG0228	four-way junction DNA binding
Verru16B_RS16445	COG0012	GTP binding
Verru16B_RS16465	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
Verru16B_RS16470	COG1984	allophanate hydrolase subunit 2
Verru16B_RS16475	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
Verru16B_RS16490	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Verru16B_RS16490	COG1333	cytochrome c biogenesis protein
Verru16B_RS16495	COG0840	transmembrane signaling receptor activity
Verru16B_RS16510	COG3005	denitrification pathway
Verru16B_RS16535	COG3622	Belongs to the hyi family
Verru16B_RS16540	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Verru16B_RS16545	COG0497	DNA recombination
Verru16B_RS16560	COG2135	peptidase activity
Verru16B_RS16565	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
Verru16B_RS16570	COG0540	Belongs to the ATCase OTCase family
Verru16B_RS16575	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Verru16B_RS16595	COG2204	response regulator
Verru16B_RS16605	COG0148	phosphopyruvate hydratase activity
Verru16B_RS16615	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
Verru16B_RS16625	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
Verru16B_RS16645	COG1063	alcohol dehydrogenase
Verru16B_RS16650	COG0156	8-amino-7-oxononanoate synthase activity
Verru16B_RS16655	COG0295	cytidine deaminase activity
Verru16B_RS16670	COG0124	histidyl-tRNA synthetase
Verru16B_RS16680	COG2226	methyltransferase
Verru16B_RS16685	COG0316	Belongs to the HesB IscA family
Verru16B_RS16690	COG0515	serine threonine protein kinase
Verru16B_RS16695	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
Verru16B_RS16700	COG1840	ABC-type Fe3 transport system, periplasmic component
Verru16B_RS16705	COG3842	ATPase activity
Verru16B_RS16710	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
Verru16B_RS16710	COG0037	tRNA processing
Verru16B_RS16725	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
Verru16B_RS16730	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
Verru16B_RS16735	COG0745	RESPONSE REGULATOR receiver
Verru16B_RS16740	COG2201	protein-glutamate methylesterase activity
Verru16B_RS16770	COG2943	transferase activity, transferring hexosyl groups
Verru16B_RS16780	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
Verru16B_RS16785	COG1573	uracil-dna glycosylase
Verru16B_RS16795	COG0495	leucyl-tRNA aminoacylation
Verru16B_RS16815	COG3206	protein involved in exopolysaccharide biosynthesis
Verru16B_RS16815	COG0489	protein tyrosine kinase activity
Verru16B_RS16820	COG3494	Protein of unknown function (DUF1009)
Verru16B_RS16830	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Verru16B_RS16835	COG2151	metal-sulfur cluster biosynthetic enzyme
Verru16B_RS16840	COG0616	signal peptide processing
Verru16B_RS16865	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
Verru16B_RS16875	COG0006	proline dipeptidase activity
Verru16B_RS16880	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Verru16B_RS16885	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
Verru16B_RS16890	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Verru16B_RS16900	COG0612	Peptidase, M16
Verru16B_RS16920	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
Verru16B_RS16930	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Verru16B_RS16935	COG0154	amidase activity
Verru16B_RS16940	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Verru16B_RS16950	COG0072	phenylalanine-tRNA ligase activity
Verru16B_RS16955	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
Verru16B_RS16960	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
Verru16B_RS16965	COG0291	Belongs to the bacterial ribosomal protein bL35 family
Verru16B_RS16970	COG0471	metal ion transport
Verru16B_RS16990	COG0811	peptide transport
Verru16B_RS16995	COG0848	biopolymer transport protein
Verru16B_RS17000	COG0848	biopolymer transport protein
Verru16B_RS17025	COG0004	ammonium transporteR
Verru16B_RS17030	COG0347	Belongs to the P(II) protein family
Verru16B_RS17040	COG0436	Aminotransferase
Verru16B_RS17050	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Verru16B_RS17055	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Verru16B_RS17065	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
Verru16B_RS17070	COG0440	acetolactate synthase activity
Verru16B_RS17080	COG0129	dihydroxy-acid dehydratase activity
Verru16B_RS17085	COG0460	homoserine dehydrogenase
Verru16B_RS17085	COG0527	aspartate kinase activity
Verru16B_RS17090	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Verru16B_RS17095	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
Verru16B_RS17100	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
Verru16B_RS17105	COG1879	ABC-type sugar transport system periplasmic component
Verru16B_RS17110	COG1129	ABC transporter
Verru16B_RS17115	COG1172	Belongs to the binding-protein-dependent transport system permease family
Verru16B_RS17120	COG1172	Belongs to the binding-protein-dependent transport system permease family
Verru16B_RS17125	COG3534	alpha-L-arabinofuranosidase
Verru16B_RS17155	COG0493	'glutamate synthase
Verru16B_RS17160	COG0067	glutamate synthase
Verru16B_RS17160	COG0069	glutamate synthase activity
Verru16B_RS17160	COG0070	glutamate synthase
Verru16B_RS17175	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
Verru16B_RS17185	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Verru16B_RS17190	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Verru16B_RS17200	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Verru16B_RS17205	COG0305	Participates in initiation and elongation during chromosome replication
Verru16B_RS17210	COG0359	binds to the 23S rRNA
Verru16B_RS17215	COG0629	single-stranded DNA binding
Verru16B_RS17225	COG0193	aminoacyl-tRNA hydrolase activity
Verru16B_RS17230	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
Verru16B_RS17275	COG0577	efflux transmembrane transporter activity
Verru16B_RS17275	COG1136	(ABC) transporter
Verru16B_RS17295	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Verru16B_RS17305	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Verru16B_RS17330	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Verru16B_RS17335	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Verru16B_RS17340	COG0772	Belongs to the SEDS family
Verru16B_RS17345	COG1388	LysM domain
Verru16B_RS17345	COG1705	Flagellar rod assembly protein muramidase FlgJ
Verru16B_RS17360	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Verru16B_RS17370	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
Verru16B_RS17375	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Verru16B_RS17380	COG0768	penicillin binding
Verru16B_RS17390	COG0275	rRNA processing
Verru16B_RS17395	COG2001	Belongs to the MraZ family
Verru16B_RS17405	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
Verru16B_RS17455	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Verru16B_RS17460	COG1879	ABC-type sugar transport system periplasmic component
Verru16B_RS17470	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Verru16B_RS17475	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Verru16B_RS17475	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
Verru16B_RS17480	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
Verru16B_RS17485	COG0288	reversible hydration of carbon dioxide
Verru16B_RS17500	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
Verru16B_RS17505	COG2226	methyltransferase
Verru16B_RS17565	COG0018	arginyl-trna synthetase
Verru16B_RS17575	COG1295	ribonuclease BN
Verru16B_RS17585	COG1077	Cell shape determining protein MreB Mrl
Verru16B_RS17605	COG0768	penicillin binding
Verru16B_RS17610	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
Verru16B_RS17630	COG0714	Associated with various cellular activities
Verru16B_RS17635	COG0025	NhaP-type Na H and K H
Verru16B_RS17645	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Verru16B_RS17650	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
Verru16B_RS17660	COG2154	pterin-4-alpha-carbinolamine dehydratase
Verru16B_RS17665	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Verru16B_RS17670	COG0575	Belongs to the CDS family
Verru16B_RS17675	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
Verru16B_RS17680	COG0750	zinc metalloprotease