locus-tag	class	description
GJ664_RS00005	COG0517	IMP dehydrogenase activity
GJ664_RS00010	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
GJ664_RS00020	COG1418	mRNA catabolic process
GJ664_RS00025	COG1482	cell wall glycoprotein biosynthetic process
GJ664_RS00035	COG1132	(ABC) transporter
GJ664_RS00045	COG1309	transcriptional regulator
GJ664_RS00050	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GJ664_RS00055	COG1278	Cold shock
GJ664_RS00080	COG1803	Methylglyoxal synthase
GJ664_RS00120	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GJ664_RS00140	COG3158	transport of potassium into the cell
GJ664_RS00150	COG2723	6-phospho-beta-galactosidase activity
GJ664_RS00155	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GJ664_RS00170	COG0589	response to stress
GJ664_RS00190	COG0166	Belongs to the GPI family
GJ664_RS00200	COG4120	Belongs to the binding-protein-dependent transport system permease family
GJ664_RS00210	COG0028	Belongs to the TPP enzyme family
GJ664_RS00255	COG3394	polysaccharide catabolic process
GJ664_RS00260	COG2190	(PTS) system
GJ664_RS00260	COG1263	PTS System
GJ664_RS00260	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GJ664_RS00265	COG0366	Alpha amylase catalytic
GJ664_RS00275	COG2188	Transcriptional regulator
GJ664_RS00295	COG4975	Glucose uptake
GJ664_RS00310	COG1368	sulfuric ester hydrolase activity
GJ664_RS00335	COG0402	S-adenosylhomocysteine deaminase activity
GJ664_RS00340	COG5002	protein histidine kinase activity
GJ664_RS00340	COG3850	Histidine kinase
GJ664_RS00345	COG0745	RESPONSE REGULATOR receiver
GJ664_RS00360	COG0531	amino acid
GJ664_RS00370	COG2826	transposase and inactivated derivatives, IS30 family
GJ664_RS00400	COG0110	maltose O-acetyltransferase activity
GJ664_RS00405	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GJ664_RS00410	COG0196	riboflavin kinase activity
GJ664_RS00415	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GJ664_RS00435	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GJ664_RS00440	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GJ664_RS00450	COG2740	Nucleic-acid-binding protein implicated in transcription termination
GJ664_RS00455	COG0195	Participates in both transcription termination and antitermination
GJ664_RS00465	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GJ664_RS00530	COG2801	Transposase and inactivated derivatives
GJ664_RS00540	COG2176	DNA-directed DNA polymerase activity
GJ664_RS00545	COG0442	prolyl-tRNA aminoacylation
GJ664_RS00550	COG0750	zinc metalloprotease
GJ664_RS00555	COG4589	Belongs to the CDS family
GJ664_RS00560	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GJ664_RS00570	COG0233	cytoplasmic translational termination
GJ664_RS00575	COG0528	UMP kinase activity
GJ664_RS00580	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GJ664_RS00585	COG0052	Belongs to the universal ribosomal protein uS2 family
GJ664_RS00590	COG2827	Endonuclease containing a URI domain
GJ664_RS00595	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GJ664_RS00600	COG0204	Acyl-transferase
GJ664_RS00605	COG1073	alpha beta
GJ664_RS00610	COG1132	(ABC) transporter
GJ664_RS00615	COG1132	(ABC) transporter
GJ664_RS00620	COG3763	UPF0154 protein
GJ664_RS00625	COG4224	UPF0291 protein
GJ664_RS00630	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GJ664_RS00635	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GJ664_RS00640	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GJ664_RS00640	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
GJ664_RS00645	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GJ664_RS00650	COG3759	membrane
GJ664_RS00655	COG0393	Putative heavy-metal-binding
GJ664_RS00690	COG0481	GTPase activity
GJ664_RS00715	COG3152	Membrane
GJ664_RS00730	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GJ664_RS00735	COG0827	DNA restriction-modification system
GJ664_RS00765	COG1459	type II secretion system
GJ664_RS00770	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GJ664_RS00775	COG0217	transcriptional regulatory protein
GJ664_RS00815	COG2855	membrane
GJ664_RS00820	COG0583	DNA-binding transcription factor activity
GJ664_RS00825	COG0534	Mate efflux family protein
GJ664_RS00835	COG0564	pseudouridine synthase activity
GJ664_RS00840	COG0431	NADPH-dependent FMN reductase
GJ664_RS00850	COG2249	NAD(P)H dehydrogenase (quinone) activity
GJ664_RS00855	COG0174	glutamine synthetase
GJ664_RS00860	COG0789	Transcriptional regulator
GJ664_RS00865	COG0519	Catalyzes the synthesis of GMP from XMP
GJ664_RS00875	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
GJ664_RS00880	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GJ664_RS00895	COG1940	carbohydrate kinase activity
GJ664_RS00910	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GJ664_RS00915	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GJ664_RS00920	COG0768	penicillin binding
GJ664_RS00935	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GJ664_RS00940	COG0708	Exodeoxyribonuclease III
GJ664_RS00945	COG2176	DNA-directed DNA polymerase activity
GJ664_RS00950	COG0697	spore germination
GJ664_RS00960	COG0802	atpase or kinase
GJ664_RS00965	COG0280	phosphate acetyltransferase
GJ664_RS00970	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GJ664_RS00975	COG0561	phosphatase activity
GJ664_RS00985	COG1811	Na channel or pump
GJ664_RS01000	COG0517	IMP dehydrogenase activity
GJ664_RS01000	COG0516	GMP reductase activity
GJ664_RS01005	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GJ664_RS01010	COG0351	phosphomethylpyrimidine kinase
GJ664_RS01020	COG4475	Protein of unknown function (DUF436)
GJ664_RS01025	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GJ664_RS01035	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GJ664_RS01055	COG1177	transmembrane transport
GJ664_RS01060	COG1176	ABC-type spermidine putrescine transport system, permease component I
GJ664_RS01065	COG3842	ATPase activity
GJ664_RS01070	COG0604	alcohol dehydrogenase
GJ664_RS01080	COG1136	(ABC) transporter
GJ664_RS01085	COG0577	efflux transmembrane transporter activity
GJ664_RS01100	COG4585	Histidine kinase
GJ664_RS01110	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GJ664_RS01115	COG0572	uridine kinase
GJ664_RS01120	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GJ664_RS01125	COG0072	phenylalanine-tRNA ligase activity
GJ664_RS01130	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GJ664_RS01135	COG1733	regulation of RNA biosynthetic process
GJ664_RS01145	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GJ664_RS01150	COG1254	Belongs to the acylphosphatase family
GJ664_RS01155	COG0706	membrane insertase activity
GJ664_RS01160	COG5002	protein histidine kinase activity
GJ664_RS01165	COG0745	RESPONSE REGULATOR receiver
GJ664_RS01170	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GJ664_RS01180	COG1323	Belongs to the UPF0348 family
GJ664_RS01185	COG2226	methyltransferase
GJ664_RS01190	COG0799	negative regulation of ribosome biogenesis
GJ664_RS01195	COG1713	HD superfamily hydrolase involved in NAD metabolism
GJ664_RS01200	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GJ664_RS01210	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GJ664_RS01225	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GJ664_RS01230	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GJ664_RS01235	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GJ664_RS01240	COG1304	FMN binding
GJ664_RS01245	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GJ664_RS01250	COG1484	DNA-dependent DNA replication
GJ664_RS01255	COG3611	Membrane attachment protein
GJ664_RS01260	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GJ664_RS01265	COG0237	dephospho-CoA kinase activity
GJ664_RS01270	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GJ664_RS01275	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GJ664_RS01275	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GJ664_RS01290	COG3584	3D domain protein
GJ664_RS01290	COG3583	domain protein
GJ664_RS01295	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GJ664_RS01300	COG0557	exoribonuclease II activity
GJ664_RS01310	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GJ664_RS01320	COG0531	amino acid
GJ664_RS01335	COG1725	Transcriptional regulator
GJ664_RS01340	COG1073	alpha beta
GJ664_RS01345	COG0018	arginyl-trna synthetase
GJ664_RS01350	COG0577	efflux transmembrane transporter activity
GJ664_RS01350	COG1136	(ABC) transporter
GJ664_RS01365	COG0531	amino acid
GJ664_RS01370	COG2267	carboxylic ester hydrolase activity
GJ664_RS01375	COG0561	phosphatase activity
GJ664_RS01390	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GJ664_RS01395	COG1187	pseudouridine synthase activity
GJ664_RS01400	COG2244	polysaccharide biosynthetic process
GJ664_RS01405	COG2814	Major facilitator Superfamily
GJ664_RS01410	COG1733	regulation of RNA biosynthetic process
GJ664_RS01415	COG1113	amino acid transport
GJ664_RS01420	COG0495	leucyl-tRNA aminoacylation
GJ664_RS01425	COG1705	Flagellar rod assembly protein muramidase FlgJ
GJ664_RS01425	COG1388	LysM domain
GJ664_RS01430	COG0671	phosphoesterase, PA-phosphatase related
GJ664_RS01435	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
GJ664_RS01440	COG3142	Participates in the control of copper homeostasis
GJ664_RS01445	COG1968	undecaprenyl-diphosphatase activity
GJ664_RS01450	COG0564	pseudouridine synthase activity
GJ664_RS01455	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GJ664_RS01460	COG2357	RelA SpoT domain protein
GJ664_RS01480	COG4862	establishment of competence for transformation
GJ664_RS01485	COG1393	Belongs to the ArsC family
GJ664_RS01490	COG1234	tRNA 3'-trailer cleavage
GJ664_RS01505	COG1136	(ABC) transporter
GJ664_RS01510	COG0745	RESPONSE REGULATOR receiver
GJ664_RS01515	COG0642	Histidine kinase
GJ664_RS01525	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GJ664_RS01530	COG0602	queuosine metabolic process
GJ664_RS01540	COG2217	Heavy metal translocating P-type atpase
GJ664_RS01565	COG0542	response to heat
GJ664_RS01585	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GJ664_RS01590	COG1253	flavin adenine dinucleotide binding
GJ664_RS01595	COG0628	permease
GJ664_RS01600	COG2153	protein acetylation
GJ664_RS01610	COG1442	glycosyl transferase family 8
GJ664_RS01615	COG3557	Belongs to the UPF0374 family
GJ664_RS01620	COG1194	a g-specific adenine glycosylase
GJ664_RS01625	COG2137	regulation of response to DNA damage stimulus
GJ664_RS01635	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GJ664_RS01655	COG3425	synthase
GJ664_RS01665	COG0183	Belongs to the thiolase family
GJ664_RS01695	COG1597	lipid kinase activity
GJ664_RS01705	COG1088	dTDP-glucose 4,6-dehydratase activity
GJ664_RS01715	COG0765	amino acid transport
GJ664_RS01725	COG0242	peptide deformylase activity
GJ664_RS01750	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GJ664_RS01795	COG0438	transferase activity, transferring glycosyl groups
GJ664_RS01800	COG1442	glycosyl transferase family 8
GJ664_RS01805	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GJ664_RS01810	COG0489	protein tyrosine kinase activity
GJ664_RS01820	COG1316	TRANSCRIPTIONal
GJ664_RS01830	COG0024	Methionine aminopeptidase
GJ664_RS01835	COG0716	FMN binding
GJ664_RS01840	COG2246	polysaccharide biosynthetic process
GJ664_RS01845	COG2246	polysaccharide biosynthetic process
GJ664_RS01850	COG0463	Glycosyl transferase, family 2
GJ664_RS01855	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GJ664_RS01865	COG2309	aminopeptidase activity
GJ664_RS01880	COG2076	Multidrug Resistance protein
GJ664_RS01900	COG0477	Major facilitator Superfamily
GJ664_RS01905	COG1827	regulation of RNA biosynthetic process
GJ664_RS01910	COG2723	6-phospho-beta-galactosidase activity
GJ664_RS01920	COG1447	Phosphotransferase system cellobiose-specific component IIA
GJ664_RS01930	COG0673	inositol 2-dehydrogenase activity
GJ664_RS01970	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GJ664_RS01975	COG1597	lipid kinase activity
GJ664_RS01980	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GJ664_RS01985	COG0154	amidase activity
GJ664_RS02010	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GJ664_RS02025	COG1609	Transcriptional regulator
GJ664_RS02030	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GJ664_RS02035	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GJ664_RS02040	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GJ664_RS02045	COG1705	Flagellar rod assembly protein muramidase FlgJ
GJ664_RS02050	COG0673	inositol 2-dehydrogenase activity
GJ664_RS02060	COG1278	Cold shock
GJ664_RS02085	COG3091	SprT-like family
GJ664_RS02090	COG2183	response to ionizing radiation
GJ664_RS02105	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GJ664_RS02110	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GJ664_RS02130	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GJ664_RS02140	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GJ664_RS02195	COG2188	Transcriptional regulator
GJ664_RS02210	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GJ664_RS02230	COG3104	oligopeptide transport
GJ664_RS02235	COG0494	nUDIX hydrolase
GJ664_RS02270	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GJ664_RS02275	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GJ664_RS02280	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GJ664_RS02290	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
GJ664_RS02295	COG0037	tRNA processing
GJ664_RS02300	COG1098	S1 RNA binding domain
GJ664_RS02310	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GJ664_RS02315	COG2244	polysaccharide biosynthetic process
GJ664_RS02320	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GJ664_RS02325	COG0193	aminoacyl-tRNA hydrolase activity
GJ664_RS02330	COG0039	L-malate dehydrogenase activity
GJ664_RS02350	COG4708	membrane
GJ664_RS02355	COG2337	Toxic component of a toxin-antitoxin (TA) module
GJ664_RS02365	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GJ664_RS02370	COG0736	holo-[acyl-carrier-protein] synthase activity
GJ664_RS02380	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GJ664_RS02390	COG0501	Belongs to the peptidase M48B family
GJ664_RS02395	COG1704	LemA family
GJ664_RS02405	COG2814	Major facilitator Superfamily
GJ664_RS02415	COG3548	integral membrane protein
GJ664_RS02425	COG0254	rRNA binding
GJ664_RS02430	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GJ664_RS02435	COG0504	CTP synthase activity
GJ664_RS02440	COG1940	carbohydrate kinase activity
GJ664_RS02445	COG3343	RNA polymerase activity
GJ664_RS02455	COG0095	Lipoate-protein ligase
GJ664_RS02460	COG1078	dGTPase activity
GJ664_RS02465	COG0561	phosphatase activity
GJ664_RS02475	COG0861	Integral membrane protein TerC family
GJ664_RS02480	COG1970	mechanosensitive ion channel activity
GJ664_RS02485	COG1737	Transcriptional regulator
GJ664_RS02490	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
GJ664_RS02495	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GJ664_RS02500	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GJ664_RS02505	COG1376	ErfK ybiS ycfS ynhG family protein
GJ664_RS02510	COG1309	transcriptional regulator
GJ664_RS02515	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GJ664_RS02520	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GJ664_RS02530	COG4466	Protein conserved in bacteria
GJ664_RS02535	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GJ664_RS02545	COG0084	hydrolase, TatD family'
GJ664_RS02550	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GJ664_RS02550	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GJ664_RS02555	COG1801	Protein of unknown function DUF72
GJ664_RS02580	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GJ664_RS02585	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GJ664_RS02590	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GJ664_RS02600	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
GJ664_RS02610	COG3639	organic phosphonate transmembrane transporter activity
GJ664_RS02620	COG0222	ribosome binding
GJ664_RS02625	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GJ664_RS02630	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GJ664_RS02635	COG2252	PERMEase
GJ664_RS02640	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GJ664_RS02645	COG0081	regulation of translation
GJ664_RS02650	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GJ664_RS02660	COG0250	Participates in transcription elongation, termination and antitermination
GJ664_RS02670	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GJ664_RS02680	COG3688	RNA-binding protein containing a PIN domain
GJ664_RS02685	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GJ664_RS02690	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GJ664_RS02695	COG0215	cysteine-tRNA ligase activity
GJ664_RS02700	COG4956	integral membrane protein (PIN domain superfamily)
GJ664_RS02705	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GJ664_RS02710	COG0756	dUTP diphosphatase activity
GJ664_RS02730	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GJ664_RS02735	COG1363	Peptidase, m42
GJ664_RS02740	COG1363	Peptidase, m42
GJ664_RS02750	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GJ664_RS02755	COG2188	Transcriptional regulator
GJ664_RS02760	COG1446	asparaginase
GJ664_RS02785	COG1285	pathogenesis
GJ664_RS02790	COG1914	H( )-stimulated, divalent metal cation uptake system
GJ664_RS02800	COG3479	Phenolic acid decarboxylase
GJ664_RS02805	COG1064	alcohol dehydrogenase
GJ664_RS02815	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GJ664_RS02870	COG1396	sequence-specific DNA binding
GJ664_RS02890	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GJ664_RS02895	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GJ664_RS02900	COG0101	tRNA pseudouridine synthase activity
GJ664_RS02945	COG1122	ATPase activity
GJ664_RS02950	COG1122	ATPase activity
GJ664_RS02955	COG0203	ribosomal protein L17
GJ664_RS02960	COG0202	RNA polymerase activity
GJ664_RS02965	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GJ664_RS02970	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GJ664_RS02975	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GJ664_RS02980	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GJ664_RS02985	COG0563	adenylate kinase activity
GJ664_RS02995	COG0200	Binds to the 23S rRNA
GJ664_RS03000	COG1841	ribosomal large subunit assembly
GJ664_RS03005	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GJ664_RS03010	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GJ664_RS03015	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GJ664_RS03020	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GJ664_RS03030	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GJ664_RS03035	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GJ664_RS03040	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GJ664_RS03045	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GJ664_RS03050	COG0255	Belongs to the universal ribosomal protein uL29 family
GJ664_RS03055	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GJ664_RS03060	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GJ664_RS03065	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GJ664_RS03070	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GJ664_RS03075	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GJ664_RS03080	COG0089	rRNA binding
GJ664_RS03085	COG0088	Forms part of the polypeptide exit tunnel
GJ664_RS03090	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GJ664_RS03095	COG0051	transcription antitermination factor activity, RNA binding
GJ664_RS03100	COG1335	isochorismatase
GJ664_RS03105	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GJ664_RS03110	COG0049	tRNA binding
GJ664_RS03115	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GJ664_RS03120	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
GJ664_RS03130	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GJ664_RS03135	COG0085	RNA polymerase activity
GJ664_RS03140	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GJ664_RS03150	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
GJ664_RS03155	COG0542	response to heat
GJ664_RS03160	COG4463	regulation of RNA biosynthetic process
GJ664_RS03240	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GJ664_RS03260	COG5617	Psort location CytoplasmicMembrane, score
GJ664_RS03270	COG1940	carbohydrate kinase activity
GJ664_RS03275	COG0366	Alpha amylase catalytic
GJ664_RS03300	COG2207	Transcriptional regulator
GJ664_RS03300	COG0662	Cupin 2, conserved barrel domain protein
GJ664_RS03305	COG0789	Transcriptional regulator
GJ664_RS03315	COG2188	Transcriptional regulator
GJ664_RS03320	COG1511	domain protein
GJ664_RS03335	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GJ664_RS03345	COG1428	Deoxynucleoside kinase
GJ664_RS03380	COG2801	Transposase and inactivated derivatives
GJ664_RS03410	COG0833	amino acid
GJ664_RS03440	COG1959	2 iron, 2 sulfur cluster binding
GJ664_RS03460	COG1757	Na H antiporter
GJ664_RS03470	COG0028	Belongs to the TPP enzyme family
GJ664_RS03475	COG2837	iron assimilation
GJ664_RS03525	COG0577	efflux transmembrane transporter activity
GJ664_RS03530	COG1136	(ABC) transporter
GJ664_RS03535	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GJ664_RS03540	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GJ664_RS03545	COG0514	ATP-dependent DNA helicase (RecQ)
GJ664_RS03585	COG2160	L-arabinose isomerase activity
GJ664_RS03605	COG1609	Transcriptional regulator
GJ664_RS03625	COG0110	maltose O-acetyltransferase activity
GJ664_RS03635	COG1174	glycine betaine transport
GJ664_RS03640	COG0517	IMP dehydrogenase activity
GJ664_RS03640	COG1125	glycine betaine transport
GJ664_RS03645	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GJ664_RS03650	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GJ664_RS03655	COG0006	proline dipeptidase activity
GJ664_RS03680	COG1363	Peptidase, m42
GJ664_RS03690	COG2814	Major facilitator Superfamily
GJ664_RS03700	COG1846	Transcriptional regulator
GJ664_RS03705	COG1063	alcohol dehydrogenase
GJ664_RS03715	COG0561	phosphatase activity
GJ664_RS03750	COG0488	(ABC) transporter
GJ664_RS03755	COG0445	tRNA wobble uridine modification
GJ664_RS03760	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GJ664_RS03765	COG1847	R3H domain protein
GJ664_RS03780	COG0706	membrane insertase activity
GJ664_RS03785	COG0594	ribonuclease P activity
GJ664_RS03790	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GJ664_RS03795	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GJ664_RS03800	COG0592	DNA-directed DNA polymerase activity
GJ664_RS03805	COG2501	S4 domain
GJ664_RS03810	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GJ664_RS03815	COG0187	DNA topoisomerase II activity
GJ664_RS03820	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GJ664_RS03825	COG0360	Binds together with S18 to 16S ribosomal RNA
GJ664_RS03830	COG0629	single-stranded DNA binding
GJ664_RS03835	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GJ664_RS03845	COG0359	binds to the 23S rRNA
GJ664_RS03850	COG0305	Participates in initiation and elongation during chromosome replication
GJ664_RS03860	COG0357	Ribosomal RNA small subunit methyltransferase G
GJ664_RS03865	COG1475	DNA binding
GJ664_RS03870	COG1192	Involved in chromosome partitioning
GJ664_RS03875	COG1475	DNA binding
GJ664_RS03880	COG4481	Protein conserved in bacteria
GJ664_RS03885	COG0012	GTP binding
GJ664_RS03895	COG1073	alpha beta
GJ664_RS03905	COG1780	Probably involved in ribonucleotide reductase function
GJ664_RS03930	COG1307	EDD domain protein, DegV family
GJ664_RS03935	COG1253	flavin adenine dinucleotide binding
GJ664_RS03940	COG0656	L-ascorbic acid biosynthetic process
GJ664_RS03955	COG2814	Major facilitator Superfamily
GJ664_RS03960	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GJ664_RS03965	COG2365	Tyrosine phosphatase family
GJ664_RS03980	COG2818	Glycosylase
GJ664_RS03990	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GJ664_RS04010	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GJ664_RS04015	COG0628	permease
GJ664_RS04030	COG1181	Belongs to the D-alanine--D-alanine ligase family
GJ664_RS04035	COG0071	Belongs to the small heat shock protein (HSP20) family
GJ664_RS04040	COG4152	abc transporter atp-binding protein
GJ664_RS04045	COG1668	transmembrane transport
GJ664_RS04050	COG3590	peptidase
GJ664_RS04055	COG0110	maltose O-acetyltransferase activity
GJ664_RS04065	COG0352	thiamine-phosphate diphosphorylase activity
GJ664_RS04070	COG0351	phosphomethylpyrimidine kinase
GJ664_RS04075	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
GJ664_RS04080	COG2190	(PTS) system
GJ664_RS04080	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GJ664_RS04080	COG1263	PTS System
GJ664_RS04095	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GJ664_RS04100	COG2252	PERMEase
GJ664_RS04110	COG3764	Sortase (surface protein transpeptidase)
GJ664_RS04115	COG3620	sequence-specific DNA binding
GJ664_RS04120	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GJ664_RS04130	COG0745	RESPONSE REGULATOR receiver
GJ664_RS04150	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GJ664_RS04155	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GJ664_RS04160	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GJ664_RS04170	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GJ664_RS04175	COG2252	PERMEase
GJ664_RS04180	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GJ664_RS04185	COG0697	spore germination
GJ664_RS04200	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GJ664_RS04205	COG2814	Major facilitator Superfamily
GJ664_RS04210	COG1288	antiporter activity
GJ664_RS04230	COG1794	racemase activity, acting on amino acids and derivatives
GJ664_RS04235	COG0588	phosphoglycerate mutase activity
GJ664_RS04255	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GJ664_RS04280	COG0735	belongs to the Fur family
GJ664_RS04320	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GJ664_RS04330	COG1940	carbohydrate kinase activity
GJ664_RS04335	COG0531	amino acid
GJ664_RS04340	COG0531	amino acid
GJ664_RS04345	COG1136	(ABC) transporter
GJ664_RS04350	COG0577	efflux transmembrane transporter activity
GJ664_RS04355	COG1904	glucuronate isomerase
GJ664_RS04360	COG1609	Transcriptional regulator
GJ664_RS04365	COG0588	phosphoglycerate mutase activity
GJ664_RS04375	COG2267	carboxylic ester hydrolase activity
GJ664_RS04380	COG0569	domain protein
GJ664_RS04380	COG0475	glutathione-regulated potassium exporter activity
GJ664_RS04385	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GJ664_RS04390	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GJ664_RS04395	COG3973	AAA domain
GJ664_RS04400	COG1072	(Pantothenic acid kinase))
GJ664_RS04405	COG0519	Catalyzes the synthesis of GMP from XMP
GJ664_RS04425	COG0494	nUDIX hydrolase
GJ664_RS04455	COG3681	Belongs to the UPF0597 family
GJ664_RS04460	COG0814	amino acid
GJ664_RS04475	COG0640	Transcriptional regulator
GJ664_RS04495	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GJ664_RS04520	COG1442	glycosyl transferase family 8
GJ664_RS04525	COG2261	transglycosylase associated protein
GJ664_RS04540	COG1302	Protein conserved in bacteria
GJ664_RS04590	COG1609	Transcriptional regulator
GJ664_RS04595	COG1874	Beta-galactosidase
GJ664_RS04605	COG1609	Transcriptional regulator
GJ664_RS04610	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GJ664_RS04615	COG1263	PTS System
GJ664_RS04615	COG2190	(PTS) system
GJ664_RS04615	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GJ664_RS04620	COG4690	dipeptidase activity
GJ664_RS04625	COG1121	(ABC) transporter
GJ664_RS04630	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GJ664_RS04655	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GJ664_RS04660	COG2723	6-phospho-beta-galactosidase activity
GJ664_RS04665	COG1940	carbohydrate kinase activity
GJ664_RS04675	COG2211	Major facilitator Superfamily
GJ664_RS04675	COG2190	(PTS) system
GJ664_RS04690	COG0531	amino acid
GJ664_RS04725	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GJ664_RS04735	COG4975	Glucose uptake
GJ664_RS04740	COG1869	D-ribose catabolic process
GJ664_RS04760	COG0477	Major facilitator Superfamily
GJ664_RS04765	COG0588	phosphoglycerate mutase activity
GJ664_RS04785	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
GJ664_RS04875	COG0446	pyridine nucleotide-disulphide oxidoreductase
GJ664_RS04930	COG3118	belongs to the thioredoxin family
GJ664_RS04935	COG1396	sequence-specific DNA binding
GJ664_RS04940	COG2807	transmembrane transport
GJ664_RS04965	COG1940	carbohydrate kinase activity
GJ664_RS04975	COG1131	(ABC) transporter
GJ664_RS04990	COG0583	DNA-binding transcription factor activity
GJ664_RS04995	COG0110	maltose O-acetyltransferase activity
GJ664_RS05000	COG4221	oxidoreductase activity
GJ664_RS05005	COG0308	aminopeptidase N
GJ664_RS05020	COG0789	Transcriptional regulator
GJ664_RS05025	COG1846	Transcriptional regulator
GJ664_RS05030	COG1132	(ABC) transporter
GJ664_RS05050	COG0656	L-ascorbic acid biosynthetic process
GJ664_RS05055	COG0789	Transcriptional regulator
GJ664_RS05065	COG1846	Transcriptional regulator
GJ664_RS05090	COG1914	H( )-stimulated, divalent metal cation uptake system
GJ664_RS05115	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GJ664_RS05120	COG1957	nucleoside hydrolase
GJ664_RS05125	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GJ664_RS05125	COG1522	sequence-specific DNA binding
GJ664_RS05130	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GJ664_RS05135	COG0135	phosphoribosylanthranilate isomerase activity
GJ664_RS05150	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GJ664_RS05155	COG0667	Aldo Keto reductase
GJ664_RS05170	COG1695	Transcriptional regulator
GJ664_RS05175	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GJ664_RS05180	COG2814	Major facilitator Superfamily
GJ664_RS05190	COG1132	(ABC) transporter
GJ664_RS05195	COG1132	(ABC) transporter
GJ664_RS05200	COG3973	AAA domain
GJ664_RS05205	COG2365	Tyrosine phosphatase family
GJ664_RS05210	COG0517	IMP dehydrogenase activity
GJ664_RS05210	COG0516	GMP reductase activity
GJ664_RS05220	COG5002	protein histidine kinase activity
GJ664_RS05225	COG1686	Belongs to the peptidase S11 family
GJ664_RS05230	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GJ664_RS05245	COG1121	(ABC) transporter
GJ664_RS05250	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GJ664_RS05260	COG1316	TRANSCRIPTIONal
GJ664_RS05265	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GJ664_RS05275	COG2188	Transcriptional regulator
GJ664_RS05280	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
GJ664_RS05285	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GJ664_RS05315	COG1737	Transcriptional regulator
GJ664_RS05320	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
GJ664_RS05330	COG2610	gluconate transmembrane transporter activity
GJ664_RS05350	COG0488	(ABC) transporter
GJ664_RS05380	COG2814	Major facilitator Superfamily
GJ664_RS05415	COG0702	epimerase
GJ664_RS05420	COG1760	l-serine dehydratase
GJ664_RS05430	COG1297	OPT oligopeptide transporter protein
GJ664_RS05445	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GJ664_RS05455	COG0561	phosphatase activity
GJ664_RS05465	COG3973	AAA domain
GJ664_RS05475	COG0534	Mate efflux family protein
GJ664_RS05490	COG0392	lysyltransferase activity
GJ664_RS05490	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GJ664_RS05495	COG2813	Specifically methylates the guanine in position
GJ664_RS05505	COG0590	tRNA wobble adenosine to inosine editing
GJ664_RS05515	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GJ664_RS05520	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GJ664_RS05525	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GJ664_RS05535	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GJ664_RS05540	COG3870	Protein conserved in bacteria
GJ664_RS05545	COG0470	DNA polymerase III
GJ664_RS05550	COG4467	Involved in initiation control of chromosome replication
GJ664_RS05570	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GJ664_RS05575	COG1214	PFAM Peptidase M22, glycoprotease
GJ664_RS05585	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GJ664_RS05595	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GJ664_RS05605	COG0488	(ABC) transporter
GJ664_RS05615	COG1266	CAAX protease self-immunity
GJ664_RS05620	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GJ664_RS05625	COG0459	protein refolding
GJ664_RS05630	COG0531	amino acid
GJ664_RS05635	COG1692	metallophosphoesterase
GJ664_RS05640	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GJ664_RS05650	COG0424	maF-like protein
GJ664_RS05660	COG0632	four-way junction helicase activity
GJ664_RS05665	COG2255	four-way junction helicase activity
GJ664_RS05670	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GJ664_RS05680	COG2235	arginine
GJ664_RS05695	COG0436	Aminotransferase
GJ664_RS05710	COG1288	antiporter activity
GJ664_RS05715	COG0343	queuine tRNA-ribosyltransferase activity
GJ664_RS05720	COG1862	Preprotein translocase
GJ664_RS05725	COG1012	belongs to the aldehyde dehydrogenase family
GJ664_RS05725	COG1454	alcohol dehydrogenase
GJ664_RS05730	COG1321	iron dependent repressor
GJ664_RS05735	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GJ664_RS05740	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GJ664_RS05745	COG4109	DRTGG domain
GJ664_RS05750	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GJ664_RS05755	COG0513	Belongs to the DEAD box helicase family
GJ664_RS05765	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GJ664_RS05770	COG4472	Bacterial protein of unknown function (DUF965)
GJ664_RS05775	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GJ664_RS05780	COG3906	Belongs to the UPF0473 family
GJ664_RS05785	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GJ664_RS05795	COG1193	negative regulation of DNA recombination
GJ664_RS05800	COG3118	belongs to the thioredoxin family
GJ664_RS05815	COG1696	Membrane protein involved in D-alanine export
GJ664_RS05820	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GJ664_RS05825	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GJ664_RS05830	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GJ664_RS05835	COG1120	ATPase activity
GJ664_RS05840	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GJ664_RS05845	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GJ664_RS05850	COG0492	ferredoxin-NADP+ reductase activity
GJ664_RS05860	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GJ664_RS05865	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GJ664_RS05885	COG0668	transmembrane transport
GJ664_RS05900	COG0006	proline dipeptidase activity
GJ664_RS05905	COG1609	Transcriptional regulator
GJ664_RS05910	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GJ664_RS05915	COG0363	glucosamine-6-phosphate deaminase activity
GJ664_RS05925	COG2814	Major facilitator Superfamily
GJ664_RS05945	COG2217	Heavy metal translocating P-type atpase
GJ664_RS05950	COG0640	Transcriptional regulator
GJ664_RS05965	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GJ664_RS05970	COG0737	Belongs to the 5'-nucleotidase family
GJ664_RS05975	COG4470	Protein conserved in bacteria
GJ664_RS05980	COG0647	UMP catabolic process
GJ664_RS05990	COG0586	Pfam SNARE associated Golgi protein
GJ664_RS05995	COG0492	ferredoxin-NADP+ reductase activity
GJ664_RS06005	COG1098	S1 RNA binding domain
GJ664_RS06180	COG0583	DNA-binding transcription factor activity
GJ664_RS06195	COG0251	oxidation-reduction process
GJ664_RS06210	COG0167	dihydroorotate dehydrogenase activity
GJ664_RS06215	COG1011	Hydrolase
GJ664_RS06230	COG3715	PTS system
GJ664_RS06235	COG3716	PTS system mannose fructose sorbose family IID component
GJ664_RS06250	COG1028	Short-chain dehydrogenase reductase Sdr
GJ664_RS06280	COG0438	transferase activity, transferring glycosyl groups
GJ664_RS06290	COG2084	Dehydrogenase
GJ664_RS06300	COG1368	sulfuric ester hydrolase activity
GJ664_RS06305	COG0735	belongs to the Fur family
GJ664_RS06355	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GJ664_RS06360	COG0477	Major facilitator Superfamily
GJ664_RS06365	COG2706	6-phosphogluconolactonase activity
GJ664_RS06375	COG0628	permease
GJ664_RS06385	COG0516	GMP reductase activity
GJ664_RS06410	COG1674	ftsk spoiiie
GJ664_RS06415	COG0612	Peptidase, M16
GJ664_RS06420	COG0612	Peptidase, M16
GJ664_RS06425	COG1028	Short-chain dehydrogenase reductase Sdr
GJ664_RS06430	COG1426	Protein conserved in bacteria
GJ664_RS06435	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GJ664_RS06440	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GJ664_RS06445	COG1418	mRNA catabolic process
GJ664_RS06450	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GJ664_RS06455	COG1739	Uncharacterized protein family UPF0029
GJ664_RS06460	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
GJ664_RS06475	COG0653	protein targeting
GJ664_RS06485	COG2884	Cell division ATP-binding protein ftsE
GJ664_RS06490	COG2177	Part of the ABC transporter FtsEX involved in
GJ664_RS06500	COG0745	RESPONSE REGULATOR receiver
GJ664_RS06505	COG5002	protein histidine kinase activity
GJ664_RS06515	COG0573	inorganic phosphate transmembrane transporter activity
GJ664_RS06520	COG0581	inorganic phosphate transmembrane transporter activity
GJ664_RS06525	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GJ664_RS06530	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GJ664_RS06535	COG0704	Plays a role in the regulation of phosphate uptake
GJ664_RS06555	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GJ664_RS06565	COG1983	PspC domain protein
GJ664_RS06575	COG1950	PFAM Membrane protein of
GJ664_RS06580	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GJ664_RS06585	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GJ664_RS06590	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GJ664_RS06600	COG0492	ferredoxin-NADP+ reductase activity
GJ664_RS06605	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GJ664_RS06615	COG0556	nucleotide-excision repair
GJ664_RS06620	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GJ664_RS06630	COG1660	Displays ATPase and GTPase activities
GJ664_RS06635	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GJ664_RS06640	COG1481	regulation of sporulation
GJ664_RS06645	COG1846	Transcriptional regulator
GJ664_RS06655	COG0740	serine-type endopeptidase activity
GJ664_RS06660	COG1705	Flagellar rod assembly protein muramidase FlgJ
GJ664_RS06665	COG1957	nucleoside hydrolase
GJ664_RS06680	COG0702	epimerase
GJ664_RS06685	COG1733	regulation of RNA biosynthetic process
GJ664_RS06690	COG4221	oxidoreductase activity
GJ664_RS06695	COG0789	Transcriptional regulator
GJ664_RS06710	COG0604	alcohol dehydrogenase
GJ664_RS06725	COG2094	Belongs to the DNA glycosylase MPG family
GJ664_RS06730	COG1131	(ABC) transporter
GJ664_RS06740	COG4585	Histidine kinase
GJ664_RS06745	COG2197	response regulator
GJ664_RS06760	COG1764	response to oxidative stress
GJ664_RS06835	COG3279	Response regulator of the LytR AlgR family
GJ664_RS06860	COG3279	Response regulator of the LytR AlgR family
GJ664_RS06910	COG1266	CAAX protease self-immunity
GJ664_RS06920	COG0446	pyridine nucleotide-disulphide oxidoreductase
GJ664_RS06945	COG0583	DNA-binding transcription factor activity
GJ664_RS06950	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GJ664_RS06955	COG0163	prenyltransferase activity
GJ664_RS06965	COG0584	glycerophosphoryl diester phosphodiesterase
GJ664_RS06970	COG4690	dipeptidase activity
GJ664_RS06985	COG2390	Transcriptional regulator
GJ664_RS06995	COG0126	phosphoglycerate kinase activity
GJ664_RS07000	COG0149	triose-phosphate isomerase activity
GJ664_RS07005	COG0148	phosphopyruvate hydratase activity
GJ664_RS07040	COG1438	arginine binding
GJ664_RS07065	COG0564	pseudouridine synthase activity
GJ664_RS07070	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GJ664_RS07075	COG3679	Belongs to the UPF0342 family
GJ664_RS07080	COG0420	3'-5' exonuclease activity
GJ664_RS07085	COG4717	serine-type aminopeptidase activity
GJ664_RS07090	COG3481	metal-dependent phosphohydrolase, HD sub domain
GJ664_RS07095	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GJ664_RS07105	COG0537	adenosine 5'-monophosphoramidase activity
GJ664_RS07110	COG1131	(ABC) transporter
GJ664_RS07115	COG4473	ABC transporter
GJ664_RS07120	COG0510	thiamine kinase activity
GJ664_RS07125	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GJ664_RS07135	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GJ664_RS07140	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GJ664_RS07145	COG0367	asparagine synthase
GJ664_RS07150	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GJ664_RS07180	COG2936	dipeptidyl-peptidase activity
GJ664_RS07185	COG1607	acyl-coa hydrolase
GJ664_RS07195	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GJ664_RS07195	COG2755	lipolytic protein G-D-S-L family
GJ664_RS07200	COG3942	CHAP domain
GJ664_RS07205	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GJ664_RS07210	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GJ664_RS07215	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GJ664_RS07220	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GJ664_RS07225	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GJ664_RS07230	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GJ664_RS07235	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GJ664_RS07240	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GJ664_RS07245	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GJ664_RS07250	COG0047	phosphoribosylformylglycinamidine synthase activity
GJ664_RS07255	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GJ664_RS07265	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GJ664_RS07270	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GJ664_RS07275	COG0138	bifunctional purine biosynthesis protein purh
GJ664_RS07280	COG0151	Belongs to the GarS family
GJ664_RS07285	COG1304	FMN binding
GJ664_RS07305	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GJ664_RS07315	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GJ664_RS07320	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GJ664_RS07325	COG1302	Protein conserved in bacteria
GJ664_RS07330	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GJ664_RS07335	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GJ664_RS07340	COG1570	exodeoxyribonuclease VII activity
GJ664_RS07345	COG1722	exodeoxyribonuclease VII activity
GJ664_RS07350	COG0142	geranyltranstransferase activity
GJ664_RS07355	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
GJ664_RS07360	COG1438	arginine binding
GJ664_RS07365	COG0497	DNA recombination
GJ664_RS07380	COG0194	GDP metabolic process
GJ664_RS07385	COG1758	RNA polymerase activity
GJ664_RS07390	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GJ664_RS07395	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GJ664_RS07400	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GJ664_RS07405	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GJ664_RS07405	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GJ664_RS07415	COG0515	serine threonine protein kinase
GJ664_RS07415	COG2815	serine threonine protein kinase
GJ664_RS07420	COG1162	GTPase activity
GJ664_RS07425	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GJ664_RS07430	COG1564	THIamine pyrophosphokinase
GJ664_RS07435	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GJ664_RS07440	COG1302	Protein conserved in bacteria
GJ664_RS07445	COG1461	Dihydroxyacetone kinase
GJ664_RS07450	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GJ664_RS07455	COG0416	fatty acid biosynthetic process
GJ664_RS07460	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GJ664_RS07465	COG4166	transmembrane transport
GJ664_RS07470	COG0601	transmembrane transport
GJ664_RS07475	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GJ664_RS07480	COG0444	Belongs to the ABC transporter superfamily
GJ664_RS07485	COG4608	Belongs to the ABC transporter superfamily
GJ664_RS07490	COG0571	ribonuclease III activity
GJ664_RS07495	COG1196	nuclear chromosome segregation
GJ664_RS07500	COG0552	protein localization to endoplasmic reticulum
GJ664_RS07520	COG3493	citrate carrier protein
GJ664_RS07530	COG3052	prosthetic group binding
GJ664_RS07550	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
GJ664_RS07555	COG1929	Belongs to the glycerate kinase type-1 family
GJ664_RS07560	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
GJ664_RS07565	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GJ664_RS07570	COG0228	four-way junction DNA binding
GJ664_RS07575	COG1837	Belongs to the UPF0109 family
GJ664_RS07580	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GJ664_RS07585	COG0336	Belongs to the RNA methyltransferase TrmD family
GJ664_RS07590	COG0335	large ribosomal subunit rRNA binding
GJ664_RS07650	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GJ664_RS07670	COG2264	protein methyltransferase activity
GJ664_RS07675	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GJ664_RS07685	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GJ664_RS07690	COG1490	D-aminoacyl-tRNA deacylase activity
GJ664_RS07710	COG2001	Belongs to the MraZ family
GJ664_RS07715	COG0275	rRNA processing
GJ664_RS07725	COG0768	penicillin binding
GJ664_RS07730	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GJ664_RS07735	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GJ664_RS07740	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GJ664_RS07755	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GJ664_RS07760	COG1799	cell septum assembly
GJ664_RS07770	COG2302	S4 RNA-binding domain
GJ664_RS07775	COG3599	regulation of cell shape
GJ664_RS07780	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GJ664_RS07810	COG1609	Transcriptional regulator
GJ664_RS07820	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GJ664_RS07825	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
GJ664_RS07830	COG2017	converts alpha-aldose to the beta-anomer
GJ664_RS07835	COG1278	Cold shock
GJ664_RS07840	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GJ664_RS07845	COG2814	Major facilitator Superfamily
GJ664_RS07855	COG3853	Toxic anion resistance protein (TelA)
GJ664_RS07865	COG0494	nUDIX hydrolase
GJ664_RS07875	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GJ664_RS07890	COG1619	proteins homologs of microcin C7 resistance protein MccF
GJ664_RS07895	COG1122	ATPase activity
GJ664_RS07905	COG0310	cobalt ion transport
GJ664_RS07910	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GJ664_RS07915	COG3875	lactate racemase activity
GJ664_RS07920	COG1691	(AIR) carboxylase
GJ664_RS07925	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
GJ664_RS07930	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
GJ664_RS07935	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GJ664_RS07945	COG1606	tRNA processing
GJ664_RS07950	COG1104	cysteine desulfurase activity
GJ664_RS07960	COG0482	sulfurtransferase activity
GJ664_RS07965	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GJ664_RS07970	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
GJ664_RS07975	COG0813	purine-nucleoside phosphorylase activity
GJ664_RS07980	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GJ664_RS07990	COG2390	Transcriptional regulator
GJ664_RS07995	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
GJ664_RS08000	COG0446	pyridine nucleotide-disulphide oxidoreductase
GJ664_RS08015	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GJ664_RS08035	COG4335	DNA alkylation repair
GJ664_RS08050	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GJ664_RS08055	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GJ664_RS08060	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GJ664_RS08070	COG1028	Short-chain dehydrogenase reductase Sdr
GJ664_RS08075	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GJ664_RS08080	COG0511	ligase activity, forming carbon-carbon bonds
GJ664_RS08085	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GJ664_RS08090	COG0439	Biotin carboxylase
GJ664_RS08095	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GJ664_RS08105	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GJ664_RS08115	COG1268	BioY protein
GJ664_RS08125	COG1956	GAF domain-containing protein
GJ664_RS08155	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GJ664_RS08175	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GJ664_RS08190	COG4493	Belongs to the UPF0637 family
GJ664_RS08195	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GJ664_RS08200	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
GJ664_RS08205	COG1104	cysteine desulfurase activity
GJ664_RS08210	COG0301	tRNA thio-modification
GJ664_RS08215	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GJ664_RS08220	COG0525	valine-tRNA ligase activity
GJ664_RS08230	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GJ664_RS08235	COG2003	Belongs to the UPF0758 family
GJ664_RS08240	COG1077	Cell shape determining protein MreB Mrl
GJ664_RS08245	COG1792	Involved in formation and maintenance of cell shape
GJ664_RS08255	COG0850	regulation of cytokinetic process
GJ664_RS08260	COG2894	cell division
GJ664_RS08265	COG0765	amino acid transport
GJ664_RS08270	COG1126	abc transporter atp-binding protein
GJ664_RS08275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GJ664_RS08280	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GJ664_RS08285	COG3103	Sh3 type 3 domain protein
GJ664_RS08285	COG0860	N-Acetylmuramoyl-L-alanine amidase
GJ664_RS08285	COG4991	sh3 domain protein
GJ664_RS08290	COG0124	histidyl-tRNA synthetase
GJ664_RS08295	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GJ664_RS08305	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GJ664_RS08310	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GJ664_RS08315	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GJ664_RS08330	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
GJ664_RS08335	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GJ664_RS08340	COG1610	YqeY-like protein
GJ664_RS08345	COG1702	phosphate starvation-inducible protein PhoH
GJ664_RS08350	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GJ664_RS08355	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GJ664_RS08365	COG1381	Involved in DNA repair and RecF pathway recombination
GJ664_RS08370	COG0752	glycyl-tRNA synthetase alpha subunit
GJ664_RS08375	COG0751	glycine-tRNA ligase activity
GJ664_RS08380	COG3189	MarR family transcriptional regulator
GJ664_RS08385	COG0358	DNA primase activity
GJ664_RS08390	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GJ664_RS08400	COG2384	SAM-dependent methyltransferase
GJ664_RS08405	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GJ664_RS08410	COG2195	Cleaves the N-terminal amino acid of tripeptides
GJ664_RS08415	COG0710	3-dehydroquinate dehydratase activity
GJ664_RS08430	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GJ664_RS08435	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
GJ664_RS08440	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GJ664_RS08445	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GJ664_RS08470	COG1942	4-Oxalocrotonate Tautomerase
GJ664_RS08475	COG0561	phosphatase activity
GJ664_RS08480	COG2151	metal-sulfur cluster biosynthetic enzyme
GJ664_RS08495	COG1304	FMN binding
GJ664_RS08510	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GJ664_RS08515	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
GJ664_RS08520	COG1074	ATP-dependent DNA helicase activity
GJ664_RS08525	COG1199	ATP-dependent helicase activity
GJ664_RS08525	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GJ664_RS08535	COG0017	Asparaginyl-tRNA synthetase
GJ664_RS08545	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GJ664_RS08550	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GJ664_RS08555	COG3331	DNA recombination
GJ664_RS08560	COG4474	Belongs to the UPF0398 family
GJ664_RS08565	COG3599	regulation of cell shape
GJ664_RS08575	COG0116	Belongs to the methyltransferase superfamily
GJ664_RS08580	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GJ664_RS08590	COG0582	viral genome integration into host DNA
GJ664_RS08610	COG2188	Transcriptional regulator
GJ664_RS08615	COG1131	(ABC) transporter
GJ664_RS08630	COG1131	(ABC) transporter
GJ664_RS08650	COG0095	Lipoate-protein ligase
GJ664_RS08655	COG3655	Transcriptional regulator
GJ664_RS08690	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GJ664_RS08705	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GJ664_RS08710	COG0328	RNA-DNA hybrid ribonuclease activity
GJ664_RS08720	COG1278	Cold shock
GJ664_RS08725	COG2759	Belongs to the formate--tetrahydrofolate ligase family
GJ664_RS08730	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GJ664_RS08735	COG0564	pseudouridine synthase activity
GJ664_RS08740	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GJ664_RS08745	COG2233	PERMEase
GJ664_RS08750	COG0540	Belongs to the ATCase OTCase family
GJ664_RS08755	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GJ664_RS08760	COG0505	Belongs to the CarA family
GJ664_RS08765	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GJ664_RS08770	COG0543	2 iron, 2 sulfur cluster binding
GJ664_RS08775	COG0167	dihydroorotate dehydrogenase activity
GJ664_RS08780	COG0284	orotidine-5'-phosphate decarboxylase activity
GJ664_RS08790	COG1293	RNA-binding protein homologous to eukaryotic snRNP
GJ664_RS08795	COG1307	EDD domain protein, DegV family
GJ664_RS08805	COG1272	protein, Hemolysin III
GJ664_RS08810	COG1307	EDD domain protein, DegV family
GJ664_RS08825	COG4974	Belongs to the 'phage' integrase family
GJ664_RS08840	COG1227	inorganic diphosphatase activity
GJ664_RS08845	COG0583	DNA-binding transcription factor activity
GJ664_RS08850	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GJ664_RS08855	COG1882	Formate acetyltransferase
GJ664_RS08860	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GJ664_RS08865	COG0187	DNA topoisomerase II activity
GJ664_RS08870	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GJ664_RS08875	COG0390	transport system, permease component
GJ664_RS08880	COG4619	ABC transporter
GJ664_RS08885	COG0351	phosphomethylpyrimidine kinase
GJ664_RS08890	COG3527	Alpha-acetolactate decarboxylase
GJ664_RS08895	COG0028	Belongs to the TPP enzyme family
GJ664_RS08905	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GJ664_RS08920	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
GJ664_RS08925	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GJ664_RS08930	COG1959	2 iron, 2 sulfur cluster binding
GJ664_RS08935	COG0702	epimerase
GJ664_RS08940	COG0758	DNA mediated transformation
GJ664_RS08945	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GJ664_RS08960	COG4479	Belongs to the UPF0346 family
GJ664_RS08970	COG2755	lipolytic protein G-D-S-L family
GJ664_RS08975	COG1307	EDD domain protein, DegV family
GJ664_RS08985	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GJ664_RS08990	COG0488	(ABC) transporter
GJ664_RS09000	COG0617	tRNA 3'-terminal CCA addition
GJ664_RS09005	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GJ664_RS09015	COG1733	regulation of RNA biosynthetic process
GJ664_RS09020	COG3397	chitin binding
GJ664_RS09025	COG2814	Major facilitator Superfamily
GJ664_RS09040	COG0577	efflux transmembrane transporter activity
GJ664_RS09040	COG1136	(ABC) transporter
GJ664_RS09045	COG0457	Tetratricopeptide repeat
GJ664_RS09055	COG1160	GTP binding
GJ664_RS09060	COG0539	negative regulation of cytoplasmic translation
GJ664_RS09065	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GJ664_RS09075	COG0514	ATP-dependent DNA helicase (RecQ)
GJ664_RS09090	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GJ664_RS09095	COG1187	pseudouridine synthase activity
GJ664_RS09100	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GJ664_RS09105	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GJ664_RS09120	COG0735	belongs to the Fur family
GJ664_RS09125	COG2996	Protein conserved in bacteria
GJ664_RS09130	COG2707	UPF0756 membrane protein
GJ664_RS09145	COG0587	DNA-directed DNA polymerase activity
GJ664_RS09160	COG0531	amino acid
GJ664_RS09170	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GJ664_RS09175	COG0542	response to heat
GJ664_RS09180	COG5416	Lipopolysaccharide assembly protein A domain
GJ664_RS09185	COG0300	oxidoreductase activity
GJ664_RS09190	COG1234	tRNA 3'-trailer cleavage
GJ664_RS09200	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GJ664_RS09210	COG1349	DNA-binding transcription factor activity
GJ664_RS09215	COG1105	Belongs to the carbohydrate kinase PfkB family
GJ664_RS09220	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GJ664_RS09220	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GJ664_RS09220	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GJ664_RS09225	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GJ664_RS09230	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GJ664_RS09235	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GJ664_RS09245	COG0322	excinuclease ABC activity
GJ664_RS09250	COG1126	abc transporter atp-binding protein
GJ664_RS09255	COG0765	amino acid transport
GJ664_RS09265	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GJ664_RS09270	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GJ664_RS09275	COG0544	peptidyl-prolyl cis-trans isomerase activity
GJ664_RS09280	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GJ664_RS09295	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GJ664_RS09300	COG0268	Binds directly to 16S ribosomal RNA
GJ664_RS09305	COG1466	dna polymerase III delta subunit
GJ664_RS09310	COG0658	competence protein
GJ664_RS09310	COG2333	competence protein COMEC
GJ664_RS09315	COG2131	deaminase
GJ664_RS09320	COG1596	polysaccharide export
GJ664_RS09320	COG1555	photosystem II stabilization
GJ664_RS09325	COG3480	Lon protease (S16) C-terminal proteolytic domain
GJ664_RS09330	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GJ664_RS09335	COG0742	ribosomal rna small subunit methyltransferase
GJ664_RS09340	COG4471	UPF0298 protein
GJ664_RS09350	COG0772	Belongs to the SEDS family
GJ664_RS09355	COG4838	Belongs to the UPF0358 family
GJ664_RS09360	COG1217	gtp-binding protein TYPA
GJ664_RS09365	COG0483	inositol monophosphate 1-phosphatase activity
GJ664_RS09370	COG4476	Belongs to the UPF0223 family
GJ664_RS09400	COG0242	peptide deformylase activity
GJ664_RS09420	COG5503	Protein of unknown function (DUF1447)
GJ664_RS09430	COG1597	lipid kinase activity
GJ664_RS09440	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GJ664_RS09450	COG1051	belongs to the nudix hydrolase family
GJ664_RS09460	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GJ664_RS09505	COG5290	Psort location Cytoplasmic, score
GJ664_RS09515	COG0719	Fe-S assembly protein
GJ664_RS09525	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GJ664_RS09530	COG0719	Fe-S assembly protein
GJ664_RS09545	COG2011	ABC-type metal ion transport system permease component
GJ664_RS09550	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GJ664_RS09555	COG0509	glycine decarboxylation via glycine cleavage system
GJ664_RS09560	COG0772	Belongs to the SEDS family
GJ664_RS09570	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GJ664_RS09585	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GJ664_RS09595	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GJ664_RS09600	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GJ664_RS09605	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GJ664_RS09610	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GJ664_RS09615	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GJ664_RS09620	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GJ664_RS09625	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GJ664_RS09630	COG0356	it plays a direct role in the translocation of protons across the membrane
GJ664_RS09635	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GJ664_RS09640	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GJ664_RS09645	COG0009	L-threonylcarbamoyladenylate synthase
GJ664_RS09650	COG2890	protein-(glutamine-N5) methyltransferase activity
GJ664_RS09655	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GJ664_RS09660	COG1435	thymidine kinase activity
GJ664_RS09665	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GJ664_RS09670	COG3442	glutamine amidotransferase
GJ664_RS09675	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GJ664_RS09675	COG0574	Belongs to the PEP-utilizing enzyme family
GJ664_RS09685	COG0783	Belongs to the Dps family
GJ664_RS09690	COG1131	(ABC) transporter
GJ664_RS09700	COG1309	transcriptional regulator
GJ664_RS09715	COG0590	tRNA wobble adenosine to inosine editing
GJ664_RS09720	COG1554	hydrolase, family 65, central catalytic
GJ664_RS09725	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GJ664_RS09730	COG0561	phosphatase activity
GJ664_RS09740	COG1192	Involved in chromosome partitioning
GJ664_RS09875	COG1196	nuclear chromosome segregation
GJ664_RS09895	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GJ664_RS09900	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GJ664_RS09905	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GJ664_RS09920	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GJ664_RS09930	COG0492	ferredoxin-NADP+ reductase activity
GJ664_RS09940	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GJ664_RS09945	COG3118	belongs to the thioredoxin family
GJ664_RS09955	COG0640	Transcriptional regulator
GJ664_RS09965	COG1733	regulation of RNA biosynthetic process
GJ664_RS09970	COG2910	NAD(P)H-binding
GJ664_RS09980	COG2801	Transposase and inactivated derivatives
GJ664_RS10015	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification