locus-tag	class	description
AL705_RS00005	COG1716	ATPase activity
AL705_RS00030	COG1253	flavin adenine dinucleotide binding
AL705_RS00035	COG1253	flavin adenine dinucleotide binding
AL705_RS00065	COG0463	Glycosyl transferase, family 2
AL705_RS00100	COG0300	oxidoreductase activity
AL705_RS00115	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AL705_RS00130	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
AL705_RS00175	COG0215	cysteine-tRNA ligase activity
AL705_RS00190	COG0167	dihydroorotate dehydrogenase activity
AL705_RS00200	COG0398	Pfam SNARE associated Golgi protein
AL705_RS00215	COG3883	PFAM NLP P60 protein
AL705_RS00215	COG0791	NLP P60 protein
AL705_RS00225	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AL705_RS00230	COG0488	(ABC) transporter
AL705_RS00240	COG2151	metal-sulfur cluster biosynthetic enzyme
AL705_RS00245	COG0822	iron-sulfur transferase activity
AL705_RS00250	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AL705_RS00255	COG0396	ATPase activity
AL705_RS00285	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AL705_RS00290	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AL705_RS00295	COG0149	triose-phosphate isomerase activity
AL705_RS00300	COG0126	phosphoglycerate kinase activity
AL705_RS00310	COG1481	regulation of sporulation
AL705_RS00320	COG0322	excinuclease ABC activity
AL705_RS00325	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AL705_RS00330	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AL705_RS00330	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AL705_RS00335	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AL705_RS00335	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AL705_RS00360	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AL705_RS00365	COG0242	peptide deformylase activity
AL705_RS00380	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AL705_RS00390	COG0194	GDP metabolic process
AL705_RS00400	COG0284	orotidine-5'-phosphate decarboxylase activity
AL705_RS00410	COG0505	Belongs to the CarA family
AL705_RS00420	COG0540	Belongs to the ATCase OTCase family
AL705_RS00425	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AL705_RS00435	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AL705_RS00440	COG0006	proline dipeptidase activity
AL705_RS00450	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AL705_RS00455	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AL705_RS00460	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AL705_RS00465	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AL705_RS00475	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AL705_RS00480	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AL705_RS00510	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AL705_RS00515	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AL705_RS00520	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AL705_RS00525	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AL705_RS00530	COG0747	negative chemotaxis
AL705_RS00535	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL705_RS00555	COG0632	four-way junction helicase activity
AL705_RS00560	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AL705_RS00570	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
AL705_RS00575	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
AL705_RS00585	COG0438	transferase activity, transferring glycosyl groups
AL705_RS00645	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AL705_RS00650	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AL705_RS00655	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AL705_RS00675	COG0569	domain protein
AL705_RS00700	COG0756	dUTP diphosphatase activity
AL705_RS00715	COG0674	pyruvate-flavodoxin oxidoreductase activity
AL705_RS00720	COG1013	pyruvate-flavodoxin oxidoreductase activity
AL705_RS00725	COG0493	'glutamate synthase
AL705_RS00725	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AL705_RS00730	COG0483	inositol monophosphate 1-phosphatase activity
AL705_RS00750	COG2264	protein methyltransferase activity
AL705_RS00760	COG1321	iron dependent repressor
AL705_RS00795	COG4221	oxidoreductase activity
AL705_RS00810	COG1472	Belongs to the glycosyl hydrolase 3 family
AL705_RS00815	COG1472	Belongs to the glycosyl hydrolase 3 family
AL705_RS00820	COG1472	Belongs to the glycosyl hydrolase 3 family
AL705_RS00830	COG1643	Atp-dependent helicase
AL705_RS00835	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AL705_RS00840	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AL705_RS00845	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AL705_RS00850	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL705_RS00850	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL705_RS00860	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AL705_RS00865	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AL705_RS00870	COG1414	Transcriptional regulator
AL705_RS00875	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AL705_RS00880	COG1196	nuclear chromosome segregation
AL705_RS00885	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AL705_RS00890	COG2137	regulation of response to DNA damage stimulus
AL705_RS00905	COG1268	BioY protein
AL705_RS00910	COG1122	ATPase activity
AL705_RS00920	COG1842	Phage shock protein A
AL705_RS00925	COG1396	sequence-specific DNA binding
AL705_RS00935	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AL705_RS00950	COG1674	ftsk spoiiie
AL705_RS00955	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AL705_RS00960	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL705_RS00965	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
AL705_RS00970	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AL705_RS00975	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AL705_RS00990	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AL705_RS01025	COG0534	Mate efflux family protein
AL705_RS01030	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AL705_RS01035	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AL705_RS01040	COG0738	Major facilitator superfamily
AL705_RS01050	COG0481	GTPase activity
AL705_RS01060	COG0779	Required for maturation of 30S ribosomal subunits
AL705_RS01075	COG0442	prolyl-tRNA aminoacylation
AL705_RS01125	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AL705_RS01130	COG0750	zinc metalloprotease
AL705_RS01135	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AL705_RS01160	COG0528	UMP kinase activity
AL705_RS01165	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AL705_RS01170	COG0052	Belongs to the universal ribosomal protein uS2 family
AL705_RS01180	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AL705_RS01185	COG2826	transposase and inactivated derivatives, IS30 family
AL705_RS01205	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AL705_RS01210	COG0681	Belongs to the peptidase S26 family
AL705_RS01220	COG0336	Belongs to the RNA methyltransferase TrmD family
AL705_RS01225	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AL705_RS01240	COG1028	Short-chain dehydrogenase reductase Sdr
AL705_RS01260	COG1196	nuclear chromosome segregation
AL705_RS01265	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AL705_RS01270	COG0571	ribonuclease III activity
AL705_RS01285	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AL705_RS01290	COG0742	ribosomal rna small subunit methyltransferase
AL705_RS01315	COG1181	Belongs to the D-alanine--D-alanine ligase family
AL705_RS01335	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AL705_RS01345	COG1278	Cold shock
AL705_RS01360	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AL705_RS01370	COG0179	Fumarylacetoacetate (FAA) hydrolase
AL705_RS01385	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AL705_RS01395	COG0028	Belongs to the TPP enzyme family
AL705_RS01400	COG0129	dihydroxy-acid dehydratase activity
AL705_RS01415	COG0205	6-phosphofructokinase activity
AL705_RS01420	COG0154	amidase activity
AL705_RS01425	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AL705_RS01435	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AL705_RS01450	COG0482	sulfurtransferase activity
AL705_RS01460	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AL705_RS01465	COG2086	electron transfer activity
AL705_RS01470	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AL705_RS01490	COG0110	maltose O-acetyltransferase activity
AL705_RS01510	COG1119	ATPase activity
AL705_RS01520	COG0366	Alpha amylase catalytic
AL705_RS01525	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AL705_RS01535	COG3118	belongs to the thioredoxin family
AL705_RS01540	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
AL705_RS01560	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AL705_RS01570	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AL705_RS01575	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AL705_RS01580	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AL705_RS01585	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AL705_RS01590	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AL705_RS01595	COG0356	it plays a direct role in the translocation of protons across the membrane
AL705_RS01620	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AL705_RS01630	COG0083	homoserine kinase activity
AL705_RS01635	COG0460	homoserine dehydrogenase
AL705_RS01640	COG0019	diaminopimelate decarboxylase activity
AL705_RS01645	COG0018	arginyl-trna synthetase
AL705_RS01660	COG0420	3'-5' exonuclease activity
AL705_RS01670	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AL705_RS01690	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AL705_RS01700	COG0567	Dehydrogenase, E1 component
AL705_RS01700	COG0508	dehydrogenase complex catalyzes the overall conversion of
AL705_RS01730	COG1477	protein flavinylation
AL705_RS01735	COG2239	Acts as a magnesium transporter
AL705_RS01750	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AL705_RS01755	COG5662	AntiSigma factor
AL705_RS01760	COG1595	DNA-templated transcription, initiation
AL705_RS01770	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AL705_RS01775	COG0297	glycogen (starch) synthase activity
AL705_RS01780	COG2226	methyltransferase
AL705_RS01790	COG0463	Glycosyl transferase, family 2
AL705_RS01800	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AL705_RS01810	COG1113	amino acid transport
AL705_RS01825	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AL705_RS01835	COG1217	gtp-binding protein TYPA
AL705_RS01840	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AL705_RS01845	COG0114	fumarate hydratase activity
AL705_RS01855	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AL705_RS01870	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AL705_RS01880	COG1063	alcohol dehydrogenase
AL705_RS01885	COG0012	GTP binding
AL705_RS01890	COG0733	neurotransmitter:sodium symporter activity
AL705_RS01895	COG0733	neurotransmitter:sodium symporter activity
AL705_RS01915	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AL705_RS01935	COG1494	fructose-1,6-bisphosphatase
AL705_RS01945	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AL705_RS01950	COG1072	(Pantothenic acid kinase))
AL705_RS01960	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AL705_RS01965	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AL705_RS01970	COG2755	lipolytic protein G-D-S-L family
AL705_RS01970	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AL705_RS02000	COG0148	phosphopyruvate hydratase activity
AL705_RS02010	COG3956	TIGRFAM MazG family protein
AL705_RS02020	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AL705_RS02030	COG1045	serine acetyltransferase
AL705_RS02040	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AL705_RS02070	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AL705_RS02075	COG3104	oligopeptide transport
AL705_RS02085	COG1024	Enoyl-CoA hydratase
AL705_RS02095	COG0488	(ABC) transporter
AL705_RS02100	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AL705_RS02105	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AL705_RS02110	COG3583	domain protein
AL705_RS02115	COG0084	hydrolase, TatD family'
AL705_RS02120	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL705_RS02140	COG1132	(ABC) transporter
AL705_RS02145	COG1132	(ABC) transporter
AL705_RS02145	COG2375	cellular response to nickel ion
AL705_RS02150	COG1309	transcriptional regulator
AL705_RS02180	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AL705_RS02185	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AL705_RS02205	COG0521	Mo-molybdopterin cofactor biosynthetic process
AL705_RS02210	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AL705_RS02215	COG2205	protein histidine kinase activity
AL705_RS02220	COG0745	RESPONSE REGULATOR receiver
AL705_RS02230	COG0254	rRNA binding
AL705_RS02235	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AL705_RS02245	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AL705_RS02250	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AL705_RS02295	COG1605	Chorismate mutase
AL705_RS02300	COG0166	Belongs to the GPI family
AL705_RS02305	COG1218	3'(2'),5'-bisphosphate nucleotidase
AL705_RS02350	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AL705_RS02355	COG2966	Psort location CytoplasmicMembrane, score
AL705_RS02380	COG0372	Belongs to the citrate synthase family
AL705_RS02385	COG2017	converts alpha-aldose to the beta-anomer
AL705_RS02420	COG1278	Cold shock
AL705_RS02425	COG1652	LysM domain
AL705_RS02460	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AL705_RS02465	COG2197	response regulator
AL705_RS02470	COG0523	cobalamin synthesis protein
AL705_RS02500	COG0587	DNA-directed DNA polymerase activity
AL705_RS02535	COG2226	methyltransferase
AL705_RS02570	COG0516	GMP reductase activity
AL705_RS02600	COG0459	protein refolding
AL705_RS02605	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AL705_RS02620	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AL705_RS02625	COG0456	acetyltransferase
AL705_RS02630	COG0456	acetyltransferase
AL705_RS02630	COG1214	PFAM Peptidase M22, glycoprotease
AL705_RS02635	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AL705_RS02640	COG0433	COG0433 Predicted ATPase
AL705_RS02655	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AL705_RS02680	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AL705_RS02685	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AL705_RS02690	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AL705_RS02715	COG1674	ftsk spoiiie
AL705_RS02730	COG2826	transposase and inactivated derivatives, IS30 family
AL705_RS02760	COG2801	Transposase and inactivated derivatives
AL705_RS02765	COG1136	(ABC) transporter
AL705_RS02765	COG0577	efflux transmembrane transporter activity
AL705_RS02785	COG2197	response regulator
AL705_RS02790	COG4585	Histidine kinase
AL705_RS02795	COG0577	efflux transmembrane transporter activity
AL705_RS02795	COG1136	(ABC) transporter
AL705_RS02805	COG4977	sequence-specific DNA binding
AL705_RS02805	COG1917	Cupin 2, conserved barrel domain protein
AL705_RS02830	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AL705_RS02850	COG1674	ftsk spoiiie
AL705_RS02860	COG1404	Belongs to the peptidase S8 family
AL705_RS02890	COG0203	ribosomal protein L17
AL705_RS02905	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AL705_RS02915	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AL705_RS02925	COG0563	adenylate kinase activity
AL705_RS02930	COG0201	protein transport
AL705_RS02940	COG1841	ribosomal large subunit assembly
AL705_RS02950	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AL705_RS02955	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AL705_RS02970	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AL705_RS02975	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AL705_RS02985	COG1070	Carbohydrate kinase
AL705_RS02995	COG0255	Belongs to the universal ribosomal protein uL29 family
AL705_RS03010	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AL705_RS03015	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AL705_RS03020	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AL705_RS03025	COG0089	rRNA binding
AL705_RS03030	COG0088	Forms part of the polypeptide exit tunnel
AL705_RS03040	COG0051	transcription antitermination factor activity, RNA binding
AL705_RS03045	COG1302	Protein conserved in bacteria
AL705_RS03075	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AL705_RS03100	COG1785	Belongs to the alkaline phosphatase family
AL705_RS03115	COG0085	RNA polymerase activity
AL705_RS03135	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AL705_RS03180	COG0142	geranyltranstransferase activity
AL705_RS03185	COG2226	methyltransferase
AL705_RS03190	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AL705_RS03200	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AL705_RS03205	COG4948	Mandelate Racemase Muconate Lactonizing
AL705_RS03245	COG0406	alpha-ribazole phosphatase activity
AL705_RS03270	COG0113	porphobilinogen synthase activity
AL705_RS03280	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL705_RS03310	COG0745	RESPONSE REGULATOR receiver
AL705_RS03315	COG5002	protein histidine kinase activity
AL705_RS03320	COG0588	phosphoglycerate mutase activity
AL705_RS03325	COG0438	transferase activity, transferring glycosyl groups
AL705_RS03330	COG0318	PFAM AMP-dependent synthetase and ligase
AL705_RS03340	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AL705_RS03355	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AL705_RS03360	COG0788	formyltetrahydrofolate deformylase activity
AL705_RS03370	COG2733	membrane
AL705_RS03385	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AL705_RS03390	COG1053	succinate dehydrogenase
AL705_RS03415	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AL705_RS03440	COG0459	protein refolding
AL705_RS03475	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AL705_RS03495	COG2326	polyphosphate kinase activity
AL705_RS03505	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AL705_RS03515	COG1131	(ABC) transporter
AL705_RS03520	COG2022	thiamine diphosphate biosynthetic process
AL705_RS03535	COG0352	thiamine-phosphate diphosphorylase activity
AL705_RS03545	COG0515	serine threonine protein kinase
AL705_RS03550	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AL705_RS03575	COG0693	protein deglycase activity
AL705_RS03595	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL705_RS03600	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AL705_RS03605	COG1396	sequence-specific DNA binding
AL705_RS03630	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AL705_RS03650	COG0343	queuine tRNA-ribosyltransferase activity
AL705_RS03670	COG0590	tRNA wobble adenosine to inosine editing
AL705_RS03680	COG0287	Prephenate dehydrogenase
AL705_RS03710	COG1028	Short-chain dehydrogenase reductase Sdr
AL705_RS03735	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AL705_RS03745	COG0803	Belongs to the bacterial solute-binding protein 9 family
AL705_RS03760	COG0785	Cytochrome C biogenesis protein
AL705_RS03770	COG0386	Belongs to the glutathione peroxidase family
AL705_RS03775	COG0110	maltose O-acetyltransferase activity
AL705_RS03905	COG0604	alcohol dehydrogenase
AL705_RS03920	COG1216	Glycosyl transferase, family 2
AL705_RS03925	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AL705_RS03945	COG1216	Glycosyl transferase, family 2
AL705_RS03995	COG0277	FAD linked oxidase domain protein
AL705_RS04000	COG1028	Short-chain dehydrogenase reductase Sdr
AL705_RS04020	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AL705_RS04070	COG2826	transposase and inactivated derivatives, IS30 family
AL705_RS04155	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AL705_RS04160	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
AL705_RS04170	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AL705_RS04170	COG5479	isomerase activity
AL705_RS04185	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AL705_RS04190	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AL705_RS04190	COG3321	synthase
AL705_RS04190	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AL705_RS04195	COG0318	PFAM AMP-dependent synthetase and ligase
AL705_RS04210	COG1216	Glycosyl transferase, family 2
AL705_RS04235	COG0561	phosphatase activity
AL705_RS04240	COG0204	Acyl-transferase
AL705_RS04250	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AL705_RS04255	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AL705_RS04260	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AL705_RS04275	COG1131	(ABC) transporter
AL705_RS04285	COG1132	(ABC) transporter
AL705_RS04315	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AL705_RS04315	COG2226	methyltransferase
AL705_RS04315	COG3433	isochorismatase activity
AL705_RS04315	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AL705_RS04315	COG2226	methyltransferase
AL705_RS04315	COG3433	isochorismatase activity
AL705_RS04335	COG0406	alpha-ribazole phosphatase activity
AL705_RS04340	COG0077	Prephenate dehydratase
AL705_RS04350	COG1316	TRANSCRIPTIONal
AL705_RS04365	COG0469	pyruvate kinase activity
AL705_RS04370	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
AL705_RS04375	COG1937	Protein conserved in bacteria
AL705_RS04395	COG1012	belongs to the aldehyde dehydrogenase family
AL705_RS04420	COG0328	RNA-DNA hybrid ribonuclease activity
AL705_RS04430	COG0778	Nitroreductase
AL705_RS04435	COG2116	formate transmembrane transporter activity
AL705_RS04445	COG2807	transmembrane transport
AL705_RS04455	COG1518	maintenance of DNA repeat elements
AL705_RS04460	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
AL705_RS04465	COG2910	NAD(P)H-binding
AL705_RS04470	COG1733	regulation of RNA biosynthetic process
AL705_RS04485	COG0181	hydroxymethylbilane synthase activity
AL705_RS04505	COG2226	methyltransferase
AL705_RS04540	COG1678	Uncharacterized ACR, COG1678
AL705_RS04545	COG0617	tRNA 3'-terminal CCA addition
AL705_RS04575	COG3118	belongs to the thioredoxin family
AL705_RS04580	COG0860	N-Acetylmuramoyl-L-alanine amidase
AL705_RS04580	COG3409	Peptidoglycan-binding domain 1 protein
AL705_RS04595	COG1192	Involved in chromosome partitioning
AL705_RS04600	COG0357	Ribosomal RNA small subunit methyltransferase G
AL705_RS04605	COG1847	R3H domain protein
AL705_RS04610	COG0706	membrane insertase activity
AL705_RS04620	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AL705_RS04630	COG0592	DNA-directed DNA polymerase activity
AL705_RS04635	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AL705_RS04640	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
AL705_RS04645	COG0187	DNA topoisomerase II activity
AL705_RS04650	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AL705_RS04665	COG1002	Type II restriction enzyme, methylase subunits
AL705_RS04680	COG0705	Rhomboid family
AL705_RS04690	COG1518	maintenance of DNA repeat elements
AL705_RS04740	COG3579	cysteine-type endopeptidase activity
AL705_RS04765	COG2815	serine threonine protein kinase
AL705_RS04765	COG0515	serine threonine protein kinase
AL705_RS04770	COG0515	serine threonine protein kinase
AL705_RS04770	COG2815	serine threonine protein kinase
AL705_RS04775	COG0515	serine threonine protein kinase
AL705_RS04780	COG0768	penicillin binding
AL705_RS04785	COG0772	Belongs to the SEDS family
AL705_RS04795	COG1716	ATPase activity
AL705_RS04800	COG1716	ATPase activity
AL705_RS04805	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AL705_RS04815	COG1511	domain protein
AL705_RS04820	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AL705_RS04865	COG0495	leucyl-tRNA aminoacylation
AL705_RS04875	COG1741	Belongs to the pirin family
AL705_RS04890	COG1028	Short-chain dehydrogenase reductase Sdr
AL705_RS04895	COG2267	carboxylic ester hydrolase activity
AL705_RS04910	COG1053	succinate dehydrogenase
AL705_RS04915	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AL705_RS04930	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL705_RS04935	COG0601	transmembrane transport
AL705_RS04940	COG4166	transmembrane transport
AL705_RS04975	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AL705_RS04985	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AL705_RS04990	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AL705_RS05005	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
AL705_RS05015	COG0300	oxidoreductase activity
AL705_RS05020	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AL705_RS05030	COG1090	epimerase
AL705_RS05065	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AL705_RS05075	COG3001	Fructosamine kinase
AL705_RS05085	COG1335	isochorismatase
AL705_RS05090	COG0531	amino acid
AL705_RS05095	COG3842	ATPase activity
AL705_RS05120	COG0028	Belongs to the TPP enzyme family
AL705_RS05145	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AL705_RS05160	COG0359	binds to the 23S rRNA
AL705_RS05165	COG0305	Participates in initiation and elongation during chromosome replication
AL705_RS05175	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AL705_RS05180	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AL705_RS05210	COG0577	efflux transmembrane transporter activity
AL705_RS05215	COG1136	(ABC) transporter
AL705_RS05215	COG0577	efflux transmembrane transporter activity
AL705_RS05220	COG0564	pseudouridine synthase activity
AL705_RS05230	COG1376	ErfK ybiS ycfS ynhG family protein
AL705_RS05240	COG3590	peptidase
AL705_RS05265	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AL705_RS05295	COG0500	methyltransferase
AL705_RS05300	COG0438	transferase activity, transferring glycosyl groups
AL705_RS05320	COG4981	capsule polysaccharide biosynthetic process
AL705_RS05350	COG0512	Glutamine amidotransferase of anthranilate synthase
AL705_RS05350	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AL705_RS05355	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AL705_RS05365	COG0159	tryptophan synthase activity
AL705_RS05390	COG5650	phosphatidylinositol metabolic process
AL705_RS05400	COG0717	Belongs to the dCTP deaminase family
AL705_RS05415	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AL705_RS05430	COG2181	nitrate reductase activity
AL705_RS05430	COG0247	lactate metabolic process
AL705_RS05460	COG0484	heat shock protein binding
AL705_RS05465	COG0789	Transcriptional regulator
AL705_RS05475	COG0542	response to heat
AL705_RS05495	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AL705_RS05500	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AL705_RS05515	COG0191	fructose-bisphosphate aldolase activity
AL705_RS05525	COG4129	membrane
AL705_RS05530	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AL705_RS05535	COG1115	amino acid carrier protein
AL705_RS05540	COG1115	amino acid carrier protein
AL705_RS05545	COG1501	Belongs to the glycosyl hydrolase 31 family
AL705_RS05550	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AL705_RS05575	COG1492	cobalamin metabolic process
AL705_RS05580	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AL705_RS05595	COG5640	endopeptidase activity
AL705_RS05600	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AL705_RS05605	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AL705_RS05610	COG0697	spore germination
AL705_RS05650	COG0651	ATP synthesis coupled electron transport
AL705_RS05655	COG1006	Multisubunit Na H antiporter MnhC subunit
AL705_RS05660	COG2111	Na H antiporter
AL705_RS05660	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AL705_RS05680	COG1408	metallophosphoesterase
AL705_RS05715	COG0596	Alpha beta hydrolase
AL705_RS05755	COG1111	helicase
AL705_RS05755	COG1205	dead DEAH box helicase
AL705_RS05775	COG1754	DNA topoisomerase type I activity
AL705_RS05775	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AL705_RS05785	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AL705_RS05800	COG2837	iron assimilation
AL705_RS05815	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
AL705_RS05835	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AL705_RS05840	COG2027	D-alanyl-D-alanine carboxypeptidase
AL705_RS05845	COG2027	D-alanyl-D-alanine carboxypeptidase
AL705_RS05850	COG0037	tRNA processing
AL705_RS05860	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AL705_RS05865	COG0302	gtp cyclohydrolase
AL705_RS05875	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AL705_RS05880	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AL705_RS05905	COG2271	Major facilitator Superfamily
AL705_RS05910	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AL705_RS05935	COG1194	a g-specific adenine glycosylase
AL705_RS05950	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AL705_RS05955	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AL705_RS05970	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AL705_RS05975	COG1121	(ABC) transporter
AL705_RS05985	COG1609	Transcriptional regulator
AL705_RS05990	COG0477	Major facilitator Superfamily
AL705_RS06005	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
AL705_RS06025	COG2723	6-phospho-beta-galactosidase activity
AL705_RS06030	COG0745	RESPONSE REGULATOR receiver
AL705_RS06035	COG2205	protein histidine kinase activity
AL705_RS06045	COG0151	Belongs to the GarS family
AL705_RS06050	COG0584	glycerophosphoryl diester phosphodiesterase
AL705_RS06060	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AL705_RS06065	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AL705_RS06075	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AL705_RS06085	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AL705_RS06100	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AL705_RS06110	COG0354	folic acid binding
AL705_RS06115	COG1271	oxidase subunit
AL705_RS06120	COG1294	oxidase, subunit
AL705_RS06125	COG4988	ABC transporter
AL705_RS06130	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AL705_RS06135	COG4044	May play a role in the intracellular transport of hydrophobic ligands
AL705_RS06150	COG0745	RESPONSE REGULATOR receiver
AL705_RS06155	COG0456	acetyltransferase
AL705_RS06170	COG0581	inorganic phosphate transmembrane transporter activity
AL705_RS06175	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AL705_RS06190	COG0427	acetyl-CoA hydrolase
AL705_RS06195	COG3830	Belongs to the UPF0237 family
AL705_RS06200	COG2848	UPF0210 protein
AL705_RS06205	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AL705_RS06210	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AL705_RS06220	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AL705_RS06225	COG2873	o-acetylhomoserine
AL705_RS06230	COG2873	o-acetylhomoserine
AL705_RS06235	COG0477	Major facilitator Superfamily
AL705_RS06245	COG2814	Major facilitator Superfamily
AL705_RS06255	COG0180	Tryptophanyl-tRNA synthetase
AL705_RS06260	COG1295	ribonuclease BN
AL705_RS06275	COG3883	PFAM NLP P60 protein
AL705_RS06275	COG0791	NLP P60 protein
AL705_RS06285	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AL705_RS06300	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AL705_RS06305	COG4770	biotin carboxylase activity
AL705_RS06315	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
AL705_RS06325	COG0424	maF-like protein
AL705_RS06330	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AL705_RS06375	COG1316	TRANSCRIPTIONal
AL705_RS06385	COG1091	dTDP-4-dehydrorhamnose reductase activity
AL705_RS06395	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AL705_RS06425	COG1482	cell wall glycoprotein biosynthetic process
AL705_RS06440	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AL705_RS06445	COG0745	RESPONSE REGULATOR receiver
AL705_RS06450	COG5002	protein histidine kinase activity
AL705_RS06455	COG5401	PFAM Sporulation and spore germination
AL705_RS06465	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AL705_RS06490	COG1162	GTPase activity
AL705_RS06495	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AL705_RS06500	COG1132	(ABC) transporter
AL705_RS06505	COG1132	(ABC) transporter
AL705_RS06510	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AL705_RS06535	COG0513	Belongs to the DEAD box helicase family
AL705_RS06570	COG0210	DNA helicase
AL705_RS06575	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AL705_RS06580	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AL705_RS06605	COG3480	Lon protease (S16) C-terminal proteolytic domain
AL705_RS06610	COG1615	UPF0182 protein
AL705_RS06625	COG1115	amino acid carrier protein
AL705_RS06630	COG4868	Belongs to the UPF0371 family
AL705_RS06645	COG4475	Protein of unknown function (DUF436)
AL705_RS06650	COG0351	phosphomethylpyrimidine kinase
AL705_RS06680	COG0483	inositol monophosphate 1-phosphatase activity
AL705_RS06695	COG0156	8-amino-7-oxononanoate synthase activity
AL705_RS06710	COG3345	alpha-galactosidase
AL705_RS06715	COG3345	alpha-galactosidase
AL705_RS06720	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AL705_RS06725	COG0668	transmembrane transport
AL705_RS06735	COG2884	Cell division ATP-binding protein ftsE
AL705_RS06740	COG2177	Part of the ABC transporter FtsEX involved in
AL705_RS06745	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AL705_RS06795	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AL705_RS06800	COG2814	Major facilitator Superfamily
AL705_RS06815	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AL705_RS06820	COG3830	Belongs to the UPF0237 family
AL705_RS06820	COG0560	Phosphoserine phosphatase
AL705_RS06825	COG4716	Myosin-crossreactive antigen
AL705_RS06840	COG1129	ABC transporter
AL705_RS06860	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AL705_RS06900	COG1376	ErfK ybiS ycfS ynhG family protein
AL705_RS06925	COG3237	CsbD-like
AL705_RS06935	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AL705_RS06940	COG0300	oxidoreductase activity
AL705_RS06985	COG3959	Transketolase, thiamine diphosphate binding domain
AL705_RS06990	COG3958	Transketolase
AL705_RS07005	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AL705_RS07020	COG0006	proline dipeptidase activity
AL705_RS07045	COG0544	peptidyl-prolyl cis-trans isomerase activity
AL705_RS07055	COG0740	serine-type endopeptidase activity
AL705_RS07060	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AL705_RS07065	COG0039	L-malate dehydrogenase activity
AL705_RS07070	COG0525	valine-tRNA ligase activity
AL705_RS07075	COG0285	dihydrofolate synthase activity
AL705_RS07080	COG0105	UTP biosynthetic process
AL705_RS07085	COG1530	ribonuclease E activity
AL705_RS07095	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AL705_RS07100	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AL705_RS07130	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AL705_RS07135	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AL705_RS07145	COG0406	alpha-ribazole phosphatase activity
AL705_RS07150	COG2755	lipolytic protein G-D-S-L family
AL705_RS07155	COG1555	photosystem II stabilization
AL705_RS07155	COG1596	polysaccharide export
AL705_RS07180	COG0481	GTPase activity
AL705_RS07190	COG0339	signal peptide processing
AL705_RS07205	COG1420	regulation of RNA biosynthetic process
AL705_RS07210	COG0484	heat shock protein binding
AL705_RS07225	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AL705_RS07240	COG1381	Involved in DNA repair and RecF pathway recombination
AL705_RS07245	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AL705_RS07255	COG0423	glycine-tRNA ligase activity
AL705_RS07260	COG2860	membrane
AL705_RS07285	COG0488	(ABC) transporter
AL705_RS07345	COG1007	ATP synthesis coupled electron transport
AL705_RS07355	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AL705_RS07360	COG0713	ATP synthesis coupled electron transport
AL705_RS07370	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AL705_RS07375	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AL705_RS07380	COG1034	ATP synthesis coupled electron transport
AL705_RS07385	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AL705_RS07395	COG0649	NAD binding
AL705_RS07400	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AL705_RS07405	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AL705_RS07460	COG0686	Belongs to the AlaDH PNT family
AL705_RS07480	COG0174	glutamine synthetase
AL705_RS07485	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AL705_RS07500	COG4558	Periplasmic binding protein
AL705_RS07505	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL705_RS07510	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AL705_RS07515	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AL705_RS07550	COG0174	glutamine synthetase
AL705_RS07565	COG0321	lipoyl(octanoyl) transferase activity
AL705_RS07570	COG0508	dehydrogenase complex catalyzes the overall conversion of
AL705_RS07575	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AL705_RS07580	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
AL705_RS07585	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AL705_RS07590	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AL705_RS07605	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL705_RS07630	COG0438	transferase activity, transferring glycosyl groups
AL705_RS07640	COG1940	carbohydrate kinase activity
AL705_RS07650	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AL705_RS07670	COG0142	geranyltranstransferase activity
AL705_RS07680	COG0456	acetyltransferase
AL705_RS07695	COG2001	Belongs to the MraZ family
AL705_RS07700	COG0275	rRNA processing
AL705_RS07710	COG0768	penicillin binding
AL705_RS07715	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AL705_RS07730	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AL705_RS07740	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AL705_RS07745	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AL705_RS07750	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AL705_RS07755	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AL705_RS07760	COG1496	oxidoreductase activity
AL705_RS07770	COG1799	cell septum assembly
AL705_RS07780	COG3599	regulation of cell shape
AL705_RS07790	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AL705_RS07805	COG0252	asparaginase activity
AL705_RS07815	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AL705_RS07830	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AL705_RS07835	COG1739	Uncharacterized protein family UPF0029
AL705_RS07850	COG2755	lipolytic protein G-D-S-L family
AL705_RS07850	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AL705_RS07855	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AL705_RS07860	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AL705_RS07870	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AL705_RS07875	COG1056	cytidyltransferase-related domain
AL705_RS07875	COG1051	belongs to the nudix hydrolase family
AL705_RS07880	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AL705_RS07895	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AL705_RS07900	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AL705_RS07905	COG0131	Imidazoleglycerol-phosphate dehydratase
AL705_RS07915	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AL705_RS07920	COG0107	imidazoleglycerol-phosphate synthase activity
AL705_RS07925	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AL705_RS07930	COG0134	indole-3-glycerol-phosphate synthase activity
AL705_RS07935	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AL705_RS07940	COG0469	pyruvate kinase activity
AL705_RS07945	COG0058	SHG alpha-glucan phosphorylase activity
AL705_RS07980	COG0539	negative regulation of cytoplasmic translation
AL705_RS07985	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AL705_RS07985	COG0237	dephospho-CoA kinase activity
AL705_RS07995	COG1609	Transcriptional regulator
AL705_RS08025	COG3973	AAA domain
AL705_RS08040	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AL705_RS08055	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AL705_RS08060	COG0072	phenylalanine-tRNA ligase activity
AL705_RS08060	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL705_RS08065	COG0352	thiamine-phosphate diphosphorylase activity
AL705_RS08065	COG0351	phosphomethylpyrimidine kinase
AL705_RS08065	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AL705_RS08070	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AL705_RS08075	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AL705_RS08080	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AL705_RS08085	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AL705_RS08095	COG1438	arginine binding
AL705_RS08100	COG0137	argininosuccinate synthase activity
AL705_RS08105	COG0165	Argininosuccinate lyase
AL705_RS08110	COG2835	tetraacyldisaccharide 4'-kinase activity
AL705_RS08115	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AL705_RS08140	COG0647	UMP catabolic process
AL705_RS08155	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AL705_RS08175	COG0504	CTP synthase activity
AL705_RS08180	COG0494	nUDIX hydrolase
AL705_RS08200	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AL705_RS08210	COG1160	GTP binding
AL705_RS08225	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family