locus-tag	class	description
LBYS_RS00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LBYS_RS00015	COG1063	alcohol dehydrogenase
LBYS_RS00020	COG1609	Transcriptional regulator
LBYS_RS00030	COG4771	TonB-dependent receptor
LBYS_RS00035	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
LBYS_RS00040	COG4771	TonB-dependent receptor
LBYS_RS00075	COG3718	enzyme involved in inositol metabolism
LBYS_RS00080	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LBYS_RS00085	COG3962	Belongs to the TPP enzyme family
LBYS_RS00090	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LBYS_RS00095	COG1012	belongs to the aldehyde dehydrogenase family
LBYS_RS00100	COG1082	Xylose isomerase domain protein TIM barrel
LBYS_RS00105	COG0673	inositol 2-dehydrogenase activity
LBYS_RS00110	COG3344	reverse transcriptase
LBYS_RS00120	COG0456	acetyltransferase
LBYS_RS00130	COG0237	dephospho-CoA kinase activity
LBYS_RS00140	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LBYS_RS00185	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LBYS_RS00185	COG0131	Imidazoleglycerol-phosphate dehydratase
LBYS_RS00200	COG1595	DNA-templated transcription, initiation
LBYS_RS00210	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
LBYS_RS00220	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LBYS_RS00225	COG1253	flavin adenine dinucleotide binding
LBYS_RS00235	COG0673	inositol 2-dehydrogenase activity
LBYS_RS00245	COG1216	Glycosyl transferase, family 2
LBYS_RS00255	COG0739	heme binding
LBYS_RS00295	COG1605	Chorismate mutase
LBYS_RS00295	COG0077	Prephenate dehydratase
LBYS_RS00305	COG0196	riboflavin kinase activity
LBYS_RS00310	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LBYS_RS00315	COG1968	undecaprenyl-diphosphatase activity
LBYS_RS00325	COG2177	Part of the ABC transporter FtsEX involved in
LBYS_RS00350	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
LBYS_RS00355	COG2204	response regulator
LBYS_RS00360	COG2884	Cell division ATP-binding protein ftsE
LBYS_RS00365	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LBYS_RS00370	COG0322	excinuclease ABC activity
LBYS_RS00375	COG2133	pyrroloquinoline quinone binding
LBYS_RS00395	COG4585	Histidine kinase
LBYS_RS00425	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LBYS_RS00435	COG4585	Histidine kinase
LBYS_RS00445	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
LBYS_RS00450	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LBYS_RS00470	COG0513	Belongs to the DEAD box helicase family
LBYS_RS00480	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LBYS_RS00495	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LBYS_RS00510	COG5002	protein histidine kinase activity
LBYS_RS00515	COG0745	RESPONSE REGULATOR receiver
LBYS_RS00525	COG3118	belongs to the thioredoxin family
LBYS_RS00545	COG0702	epimerase
LBYS_RS00550	COG4771	TonB-dependent receptor
LBYS_RS00560	COG1028	Short-chain dehydrogenase reductase Sdr
LBYS_RS00700	COG4974	Belongs to the 'phage' integrase family
LBYS_RS00880	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
LBYS_RS00905	COG0551	DNA topoisomerase type I activity
LBYS_RS00905	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LBYS_RS00935	COG1028	Short-chain dehydrogenase reductase Sdr
LBYS_RS00950	COG0604	alcohol dehydrogenase
LBYS_RS00960	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LBYS_RS00970	COG0667	Aldo Keto reductase
LBYS_RS00985	COG1028	Short-chain dehydrogenase reductase Sdr
LBYS_RS00990	COG0667	Aldo Keto reductase
LBYS_RS01010	COG0667	Aldo Keto reductase
LBYS_RS01015	COG1902	pentaerythritol trinitrate reductase activity
LBYS_RS01050	COG1506	peptidase
LBYS_RS01050	COG0823	Involved in the tonB-independent uptake of proteins
LBYS_RS01055	COG2207	Transcriptional regulator
LBYS_RS01060	COG0813	purine-nucleoside phosphorylase activity
LBYS_RS01065	COG1012	belongs to the aldehyde dehydrogenase family
LBYS_RS01070	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LBYS_RS01080	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
LBYS_RS01105	COG1012	belongs to the aldehyde dehydrogenase family
LBYS_RS01110	COG1959	2 iron, 2 sulfur cluster binding
LBYS_RS01115	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LBYS_RS01115	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LBYS_RS01120	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LBYS_RS01125	COG0438	transferase activity, transferring glycosyl groups
LBYS_RS01145	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
LBYS_RS01160	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LBYS_RS01160	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LBYS_RS01165	COG0730	response to heat
LBYS_RS01185	COG3186	Phenylalanine-4-hydroxylase
LBYS_RS01195	COG0612	Peptidase, M16
LBYS_RS01200	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
LBYS_RS01205	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LBYS_RS01215	COG1012	belongs to the aldehyde dehydrogenase family
LBYS_RS01230	COG1215	transferase activity, transferring glycosyl groups
LBYS_RS01240	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
LBYS_RS01305	COG0438	transferase activity, transferring glycosyl groups
LBYS_RS01330	COG3292	Two component regulator propeller
LBYS_RS01330	COG0745	RESPONSE REGULATOR receiver
LBYS_RS01330	COG2205	protein histidine kinase activity
LBYS_RS01330	COG0745	RESPONSE REGULATOR receiver
LBYS_RS01330	COG2205	protein histidine kinase activity
LBYS_RS01330	COG3292	Two component regulator propeller
LBYS_RS01335	COG4771	TonB-dependent receptor
LBYS_RS01340	COG0702	epimerase
LBYS_RS01350	COG2382	esterase
LBYS_RS01355	COG1472	Belongs to the glycosyl hydrolase 3 family
LBYS_RS01360	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
LBYS_RS01365	COG2851	Citrate transporter
LBYS_RS01390	COG2963	transposase activity
LBYS_RS01420	COG0431	NADPH-dependent FMN reductase
LBYS_RS01455	COG3279	Response regulator of the LytR AlgR family
LBYS_RS01460	COG3275	phosphorelay sensor kinase activity
LBYS_RS01485	COG2076	Multidrug Resistance protein
LBYS_RS01535	COG2027	D-alanyl-D-alanine carboxypeptidase
LBYS_RS01540	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
LBYS_RS01545	COG0825	malonyl-CoA metabolic process
LBYS_RS01550	COG1011	Hydrolase
LBYS_RS01575	COG0180	Tryptophanyl-tRNA synthetase
LBYS_RS01580	COG0671	phosphoesterase, PA-phosphatase related
LBYS_RS01590	COG0667	Aldo Keto reductase
LBYS_RS01635	COG2963	transposase activity
LBYS_RS01640	COG1959	2 iron, 2 sulfur cluster binding
LBYS_RS01645	COG3278	Belongs to the heme-copper respiratory oxidase family
LBYS_RS01685	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
LBYS_RS01690	COG2801	Transposase and inactivated derivatives
LBYS_RS01705	COG2080	2 iron, 2 sulfur cluster binding
LBYS_RS01710	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
LBYS_RS01715	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LBYS_RS01745	COG3250	beta-galactosidase activity
LBYS_RS01755	COG4771	TonB-dependent receptor
LBYS_RS01760	COG3292	Two component regulator propeller
LBYS_RS01760	COG2205	protein histidine kinase activity
LBYS_RS01760	COG0745	RESPONSE REGULATOR receiver
LBYS_RS01765	COG1349	DNA-binding transcription factor activity
LBYS_RS01770	COG1629	transport
LBYS_RS01775	COG0702	epimerase
LBYS_RS01780	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LBYS_RS01785	COG2271	Major facilitator Superfamily
LBYS_RS01790	COG0445	tRNA wobble uridine modification
LBYS_RS01800	COG2814	Major facilitator Superfamily
LBYS_RS01805	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LBYS_RS01810	COG1070	Carbohydrate kinase
LBYS_RS01815	COG1070	Carbohydrate kinase
LBYS_RS01820	COG0406	alpha-ribazole phosphatase activity
LBYS_RS01840	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LBYS_RS01855	COG4771	TonB-dependent receptor
LBYS_RS01860	COG0702	epimerase
LBYS_RS01880	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LBYS_RS01885	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LBYS_RS01890	COG0351	phosphomethylpyrimidine kinase
LBYS_RS01895	COG0352	thiamine-phosphate diphosphorylase activity
LBYS_RS01900	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
LBYS_RS01925	COG0513	Belongs to the DEAD box helicase family
LBYS_RS01980	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LBYS_RS02000	COG1733	regulation of RNA biosynthetic process
LBYS_RS02010	COG1733	regulation of RNA biosynthetic process
LBYS_RS02025	COG2205	protein histidine kinase activity
LBYS_RS02025	COG0784	Response regulator, receiver
LBYS_RS02080	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LBYS_RS02085	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
LBYS_RS02100	COG0640	Transcriptional regulator
LBYS_RS02105	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LBYS_RS02155	COG0252	asparaginase activity
LBYS_RS02165	COG2086	electron transfer activity
LBYS_RS02170	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
LBYS_RS02175	COG2885	chlorophyll binding
LBYS_RS02180	COG0463	Glycosyl transferase, family 2
LBYS_RS02200	COG0509	glycine decarboxylation via glycine cleavage system
LBYS_RS02205	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LBYS_RS02230	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LBYS_RS02235	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
LBYS_RS02245	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
LBYS_RS02275	COG0084	hydrolase, TatD family'
LBYS_RS02285	COG0673	inositol 2-dehydrogenase activity
LBYS_RS02290	COG1247	-acetyltransferase
LBYS_RS02300	COG2855	membrane
LBYS_RS02310	COG0745	RESPONSE REGULATOR receiver
LBYS_RS02310	COG3292	Two component regulator propeller
LBYS_RS02310	COG2205	protein histidine kinase activity
LBYS_RS02315	COG3292	Two component regulator propeller
LBYS_RS02315	COG2205	protein histidine kinase activity
LBYS_RS02315	COG0745	RESPONSE REGULATOR receiver
LBYS_RS02320	COG0745	RESPONSE REGULATOR receiver
LBYS_RS02320	COG2205	protein histidine kinase activity
LBYS_RS02320	COG3292	Two component regulator propeller
LBYS_RS02330	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LBYS_RS02335	COG4591	ABC-type transport system involved in lipoprotein release permease component
LBYS_RS02350	COG0514	ATP-dependent DNA helicase (RecQ)
LBYS_RS02355	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LBYS_RS02355	COG0517	IMP dehydrogenase activity
LBYS_RS02360	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
LBYS_RS02370	COG0649	NAD binding
LBYS_RS02380	COG1045	serine acetyltransferase
LBYS_RS02385	COG2226	methyltransferase
LBYS_RS02390	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LBYS_RS02390	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
LBYS_RS02425	COG4771	TonB-dependent receptor
LBYS_RS02440	COG0438	transferase activity, transferring glycosyl groups
LBYS_RS02450	COG0438	transferase activity, transferring glycosyl groups
LBYS_RS02450	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LBYS_RS02460	COG0702	epimerase
LBYS_RS02465	COG0456	acetyltransferase
LBYS_RS02470	COG0156	8-amino-7-oxononanoate synthase activity
LBYS_RS02485	COG0577	efflux transmembrane transporter activity
LBYS_RS02485	COG1136	(ABC) transporter
LBYS_RS02500	COG3852	Histidine kinase
LBYS_RS02510	COG2205	protein histidine kinase activity
LBYS_RS02510	COG3850	Histidine kinase
LBYS_RS02510	COG4999	Histidine kinase
LBYS_RS02510	COG3437	response regulator, receiver
LBYS_RS02515	COG0745	RESPONSE REGULATOR receiver
LBYS_RS02535	COG1090	epimerase
LBYS_RS02550	COG0443	Heat shock 70 kDa protein
LBYS_RS02590	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
LBYS_RS02595	COG0438	transferase activity, transferring glycosyl groups
LBYS_RS02610	COG3279	Response regulator of the LytR AlgR family
LBYS_RS02630	COG3415	Transposase
LBYS_RS02630	COG2801	Transposase and inactivated derivatives
LBYS_RS02655	COG2963	transposase activity
LBYS_RS02680	COG2132	Multicopper oxidase
LBYS_RS02705	COG2217	Heavy metal translocating P-type atpase
LBYS_RS02760	COG0463	Glycosyl transferase, family 2
LBYS_RS02765	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LBYS_RS02775	COG0706	membrane insertase activity
LBYS_RS02780	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LBYS_RS02795	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LBYS_RS02825	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LBYS_RS02830	COG0116	Belongs to the methyltransferase superfamily
LBYS_RS02870	COG0587	DNA-directed DNA polymerase activity
LBYS_RS02875	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LBYS_RS02885	COG2814	Major facilitator Superfamily
LBYS_RS02910	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LBYS_RS02925	COG0495	leucyl-tRNA aminoacylation
LBYS_RS02955	COG0438	transferase activity, transferring glycosyl groups
LBYS_RS02960	COG1132	(ABC) transporter
LBYS_RS02975	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LBYS_RS02980	COG0124	histidyl-tRNA synthetase
LBYS_RS02995	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
LBYS_RS03000	COG0564	pseudouridine synthase activity
LBYS_RS03005	COG0673	inositol 2-dehydrogenase activity
LBYS_RS03015	COG0632	four-way junction helicase activity
LBYS_RS03025	COG0148	phosphopyruvate hydratase activity
LBYS_RS03035	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LBYS_RS03055	COG1132	(ABC) transporter
LBYS_RS03070	COG0681	Belongs to the peptidase S26 family
LBYS_RS03090	COG1166	arginine decarboxylase activity
LBYS_RS03095	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LBYS_RS03110	COG0083	homoserine kinase activity
LBYS_RS03120	COG0640	Transcriptional regulator
LBYS_RS03130	COG2095	MarC family integral membrane protein
LBYS_RS03140	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
LBYS_RS03150	COG0424	maF-like protein
LBYS_RS03155	COG1846	Transcriptional regulator
LBYS_RS03170	COG0540	Belongs to the ATCase OTCase family
LBYS_RS03175	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LBYS_RS03200	COG1215	transferase activity, transferring glycosyl groups
LBYS_RS03205	COG0438	transferase activity, transferring glycosyl groups
LBYS_RS03225	COG0542	response to heat
LBYS_RS03240	COG1215	transferase activity, transferring glycosyl groups
LBYS_RS03245	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LBYS_RS03245	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LBYS_RS03250	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
LBYS_RS03280	COG0673	inositol 2-dehydrogenase activity
LBYS_RS03285	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
LBYS_RS03295	COG0519	Catalyzes the synthesis of GMP from XMP
LBYS_RS03305	COG3530	Putative quorum-sensing-regulated virulence factor
LBYS_RS03310	COG3781	membrane
LBYS_RS03325	COG0280	phosphate acetyltransferase
LBYS_RS03325	COG0281	malic enzyme
LBYS_RS03400	COG4585	Histidine kinase
LBYS_RS03410	COG0302	gtp cyclohydrolase
LBYS_RS03420	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LBYS_RS03435	COG0698	ribose 5-phosphate isomerase
LBYS_RS03460	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
LBYS_RS03475	COG0713	ATP synthesis coupled electron transport
LBYS_RS03490	COG2827	Endonuclease containing a URI domain
LBYS_RS03505	COG2249	NAD(P)H dehydrogenase (quinone) activity
LBYS_RS03520	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LBYS_RS03525	COG1289	transmembrane transporter activity
LBYS_RS03550	COG1335	isochorismatase
LBYS_RS03565	COG5654	RES domain protein
LBYS_RS03575	COG1201	RNA secondary structure unwinding
LBYS_RS03585	COG3153	acetyltransferase
LBYS_RS03585	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LBYS_RS03600	COG0679	Auxin Efflux Carrier
LBYS_RS03615	COG0443	Heat shock 70 kDa protein
LBYS_RS03620	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LBYS_RS03625	COG0408	coproporphyrinogen oxidase activity
LBYS_RS03635	COG1663	tetraacyldisaccharide 4'-kinase activity
LBYS_RS03655	COG2308	Evidence 4 Homologs of previously reported genes of
LBYS_RS03665	COG2801	Transposase and inactivated derivatives
LBYS_RS03670	COG2963	transposase activity
LBYS_RS03685	COG0181	hydroxymethylbilane synthase activity
LBYS_RS03700	COG1169	isochorismate synthase
LBYS_RS03725	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LBYS_RS03745	COG1619	proteins homologs of microcin C7 resistance protein MccF
LBYS_RS03755	COG0423	glycine-tRNA ligase activity
LBYS_RS03775	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LBYS_RS03785	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
LBYS_RS03790	COG3537	Alpha-1,2-mannosidase
LBYS_RS03795	COG2877	3-deoxy-8-phosphooctulonate synthase activity
LBYS_RS03805	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LBYS_RS03850	COG2963	transposase activity
LBYS_RS03860	COG1733	regulation of RNA biosynthetic process
LBYS_RS03880	COG1373	ATPase (AAA superfamily
LBYS_RS03885	COG2169	Transcriptional regulator
LBYS_RS03915	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LBYS_RS03940	COG1131	(ABC) transporter
LBYS_RS03965	COG2814	Major facilitator Superfamily
LBYS_RS03980	COG0242	peptide deformylase activity
LBYS_RS04000	COG0488	(ABC) transporter
LBYS_RS04005	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LBYS_RS04010	COG2963	transposase activity
LBYS_RS04035	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LBYS_RS04065	COG0588	phosphoglycerate mutase activity
LBYS_RS04080	COG0667	Aldo Keto reductase
LBYS_RS04100	COG2234	aminopeptidase activity
LBYS_RS04110	COG1741	Belongs to the pirin family
LBYS_RS04115	COG3279	Response regulator of the LytR AlgR family
LBYS_RS04130	COG0702	epimerase
LBYS_RS04135	COG4771	TonB-dependent receptor
LBYS_RS04145	COG0745	RESPONSE REGULATOR receiver
LBYS_RS04145	COG2205	protein histidine kinase activity
LBYS_RS04145	COG3292	Two component regulator propeller
LBYS_RS04150	COG0346	lactoylglutathione lyase activity
LBYS_RS04155	COG1363	Peptidase, m42
LBYS_RS04165	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LBYS_RS04170	COG0396	ATPase activity
LBYS_RS04175	COG0719	Fe-S assembly protein
LBYS_RS04180	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LBYS_RS04185	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
LBYS_RS04190	COG2166	iron-sulfur cluster assembly
LBYS_RS04195	COG2151	metal-sulfur cluster biosynthetic enzyme
LBYS_RS04205	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LBYS_RS04210	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LBYS_RS04260	COG0095	Lipoate-protein ligase
LBYS_RS04270	COG1522	sequence-specific DNA binding
LBYS_RS04300	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LBYS_RS04330	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
LBYS_RS04335	COG1331	Highly conserved protein containing a thioredoxin domain
LBYS_RS04360	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LBYS_RS04365	COG0261	This protein binds to 23S rRNA in the presence of protein L20
LBYS_RS04375	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LBYS_RS04400	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LBYS_RS04410	COG0228	four-way junction DNA binding
LBYS_RS04415	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LBYS_RS04420	COG0336	Belongs to the RNA methyltransferase TrmD family
LBYS_RS04425	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LBYS_RS04490	COG1247	-acetyltransferase
LBYS_RS04520	COG3781	membrane
LBYS_RS04525	COG0025	NhaP-type Na H and K H
LBYS_RS04565	COG2171	N-acyltransferase activity
LBYS_RS04575	COG0220	tRNA (guanine-N7-)-methyltransferase activity
LBYS_RS04580	COG0285	dihydrofolate synthase activity
LBYS_RS04610	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LBYS_RS04615	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
LBYS_RS04625	COG1475	DNA binding
LBYS_RS04635	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LBYS_RS04640	COG1185	polyribonucleotide nucleotidyltransferase activity
LBYS_RS04645	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LBYS_RS04665	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LBYS_RS04720	COG3655	Transcriptional regulator
LBYS_RS04765	COG3279	Response regulator of the LytR AlgR family
LBYS_RS04810	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LBYS_RS04810	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LBYS_RS04815	COG0730	response to heat
LBYS_RS04840	COG4372	Transposase
LBYS_RS04865	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LBYS_RS04925	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LBYS_RS04935	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LBYS_RS04940	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LBYS_RS04945	COG1388	LysM domain
LBYS_RS04945	COG3942	CHAP domain
LBYS_RS04950	COG3344	reverse transcriptase
LBYS_RS04965	COG1028	Short-chain dehydrogenase reductase Sdr
LBYS_RS04970	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LBYS_RS04985	COG2318	DinB family
LBYS_RS04990	COG0483	inositol monophosphate 1-phosphatase activity
LBYS_RS05000	COG0542	response to heat
LBYS_RS05015	COG0009	L-threonylcarbamoyladenylate synthase
LBYS_RS05020	COG0101	tRNA pseudouridine synthase activity
LBYS_RS05025	COG2211	Major facilitator Superfamily
LBYS_RS05055	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
LBYS_RS05070	COG1702	phosphate starvation-inducible protein PhoH
LBYS_RS05075	COG0305	Participates in initiation and elongation during chromosome replication
LBYS_RS05080	COG0673	inositol 2-dehydrogenase activity
LBYS_RS05085	COG1960	acyl-CoA dehydrogenase activity
LBYS_RS05095	COG2235	arginine
LBYS_RS05105	COG0673	inositol 2-dehydrogenase activity
LBYS_RS05155	COG1401	restriction endodeoxyribonuclease activity
LBYS_RS05330	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LBYS_RS05335	COG0456	acetyltransferase
LBYS_RS05345	COG0697	spore germination
LBYS_RS05350	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LBYS_RS05360	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LBYS_RS05395	COG0590	tRNA wobble adenosine to inosine editing
LBYS_RS05410	COG2963	transposase activity
LBYS_RS05465	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LBYS_RS05480	COG0045	succinate-CoA ligase (ADP-forming) activity
LBYS_RS05485	COG1136	(ABC) transporter
LBYS_RS05495	COG0745	RESPONSE REGULATOR receiver
LBYS_RS05500	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LBYS_RS05510	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LBYS_RS05520	COG0514	ATP-dependent DNA helicase (RecQ)
LBYS_RS05530	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
LBYS_RS05535	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LBYS_RS05545	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
LBYS_RS05550	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LBYS_RS05555	COG0193	aminoacyl-tRNA hydrolase activity
LBYS_RS05570	COG0602	queuosine metabolic process
LBYS_RS05575	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
LBYS_RS05595	COG2885	chlorophyll binding
LBYS_RS05600	COG3118	belongs to the thioredoxin family
LBYS_RS05605	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LBYS_RS05620	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
LBYS_RS05645	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LBYS_RS05655	COG0004	ammonium transporteR
LBYS_RS05660	COG3344	reverse transcriptase
LBYS_RS05665	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LBYS_RS05670	COG0174	glutamine synthetase
LBYS_RS05675	COG1796	DNA polymerase
LBYS_RS05675	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LBYS_RS05695	COG2204	response regulator
LBYS_RS05700	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LBYS_RS05725	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LBYS_RS05730	COG0291	Belongs to the bacterial ribosomal protein bL35 family
LBYS_RS05755	COG2963	transposase activity
LBYS_RS05765	COG0783	Belongs to the Dps family
LBYS_RS05770	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LBYS_RS05780	COG2153	protein acetylation
LBYS_RS05785	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LBYS_RS05800	COG0791	NLP P60 protein
LBYS_RS05805	COG0823	Involved in the tonB-independent uptake of proteins
LBYS_RS05815	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LBYS_RS05835	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
LBYS_RS05845	COG0254	rRNA binding
LBYS_RS05850	COG1803	Methylglyoxal synthase
LBYS_RS05870	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LBYS_RS05875	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LBYS_RS05880	COG0714	Associated with various cellular activities
LBYS_RS05890	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LBYS_RS05895	COG0484	heat shock protein binding
LBYS_RS05920	COG0179	Fumarylacetoacetate (FAA) hydrolase
LBYS_RS05930	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LBYS_RS05945	COG3959	Transketolase, thiamine diphosphate binding domain
LBYS_RS05950	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LBYS_RS05985	COG1946	Acyl-CoA thioesterase
LBYS_RS05990	COG2070	2-Nitropropane dioxygenase
LBYS_RS06000	COG0482	sulfurtransferase activity
LBYS_RS06025	COG0519	Catalyzes the synthesis of GMP from XMP
LBYS_RS06025	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LBYS_RS06030	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LBYS_RS06035	COG0110	maltose O-acetyltransferase activity
LBYS_RS06045	COG0402	S-adenosylhomocysteine deaminase activity
LBYS_RS06050	COG1228	amidohydrolase
LBYS_RS06065	COG0772	Belongs to the SEDS family
LBYS_RS06075	COG2388	GCN5-related N-acetyl-transferase
LBYS_RS06100	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LBYS_RS06105	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LBYS_RS06110	COG1914	H( )-stimulated, divalent metal cation uptake system
LBYS_RS06120	COG2003	Belongs to the UPF0758 family
LBYS_RS06125	COG0268	Binds directly to 16S ribosomal RNA
LBYS_RS06135	COG1473	amidohydrolase
LBYS_RS06140	COG0009	L-threonylcarbamoyladenylate synthase
LBYS_RS06145	COG4771	TonB-dependent receptor
LBYS_RS06150	COG0702	epimerase
LBYS_RS06155	COG1960	acyl-CoA dehydrogenase activity
LBYS_RS06180	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LBYS_RS06185	COG0668	transmembrane transport
LBYS_RS06190	COG0386	Belongs to the glutathione peroxidase family
LBYS_RS06195	COG1575	Belongs to the MenA family. Type 1 subfamily
LBYS_RS06215	COG2183	response to ionizing radiation
LBYS_RS06225	COG2081	HI0933 family
LBYS_RS06235	COG1741	Belongs to the pirin family
LBYS_RS06240	COG0427	acetyl-CoA hydrolase
LBYS_RS06255	COG1472	Belongs to the glycosyl hydrolase 3 family
LBYS_RS06265	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LBYS_RS06270	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LBYS_RS06275	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LBYS_RS06280	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
LBYS_RS06285	COG4145	pantothenate transmembrane transporter activity
LBYS_RS06290	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LBYS_RS06300	COG2197	response regulator
LBYS_RS06345	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LBYS_RS06350	COG1981	membrane
LBYS_RS06365	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LBYS_RS06380	COG0579	oxidoreductase
LBYS_RS06390	COG2885	chlorophyll binding
LBYS_RS06400	COG0504	CTP synthase activity
LBYS_RS06405	COG0604	alcohol dehydrogenase
LBYS_RS06410	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LBYS_RS06415	COG0784	Response regulator, receiver
LBYS_RS06415	COG2198	Histidine kinase
LBYS_RS06415	COG5002	protein histidine kinase activity
LBYS_RS06425	COG1652	LysM domain
LBYS_RS06445	COG0813	purine-nucleoside phosphorylase activity
LBYS_RS06460	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LBYS_RS06465	COG0459	protein refolding
LBYS_RS06485	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
LBYS_RS06490	COG0828	Belongs to the bacterial ribosomal protein bS21 family
LBYS_RS06495	COG4974	Belongs to the 'phage' integrase family
LBYS_RS06530	COG0006	proline dipeptidase activity
LBYS_RS06550	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LBYS_RS06555	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LBYS_RS06560	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LBYS_RS06570	COG0598	Magnesium transport protein CorA
LBYS_RS06580	COG0564	pseudouridine synthase activity
LBYS_RS06590	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
LBYS_RS06610	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
LBYS_RS06615	COG0508	dehydrogenase complex catalyzes the overall conversion of
LBYS_RS06620	COG0481	GTPase activity
LBYS_RS06635	COG0577	efflux transmembrane transporter activity
LBYS_RS06865	COG4372	Transposase
LBYS_RS06890	COG1733	regulation of RNA biosynthetic process
LBYS_RS06900	COG3012	SEC-C Motif Domain Protein
LBYS_RS06950	COG4946	Tricorn protease homolog
LBYS_RS06950	COG0793	Belongs to the peptidase S41A family
LBYS_RS06965	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LBYS_RS06970	COG0508	dehydrogenase complex catalyzes the overall conversion of
LBYS_RS06970	COG0022	dehydrogenase e1 component
LBYS_RS06975	COG4232	protein-disulfide reductase activity
LBYS_RS06980	COG1473	amidohydrolase
LBYS_RS07000	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LBYS_RS07020	COG2815	serine threonine protein kinase
LBYS_RS07020	COG0515	serine threonine protein kinase
LBYS_RS07025	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LBYS_RS07045	COG1764	response to oxidative stress
LBYS_RS07050	COG0227	Belongs to the bacterial ribosomal protein bL28 family
LBYS_RS07055	COG1490	D-aminoacyl-tRNA deacylase activity
LBYS_RS07060	COG2239	Acts as a magnesium transporter
LBYS_RS07065	COG3537	Alpha-1,2-mannosidase
LBYS_RS07070	COG2755	lipolytic protein G-D-S-L family
LBYS_RS07070	COG0657	acetylesterase activity
LBYS_RS07075	COG1506	peptidase
LBYS_RS07075	COG0823	Involved in the tonB-independent uptake of proteins
LBYS_RS07085	COG4895	conserved protein (DUF2196)
LBYS_RS07090	COG1136	(ABC) transporter
LBYS_RS07095	COG1136	(ABC) transporter
LBYS_RS07095	COG0577	efflux transmembrane transporter activity
LBYS_RS07110	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
LBYS_RS07135	COG0259	pyridoxamine-phosphate oxidase activity
LBYS_RS07150	COG0497	DNA recombination
LBYS_RS07160	COG1999	signal sequence binding
LBYS_RS07180	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
LBYS_RS07185	COG0673	inositol 2-dehydrogenase activity
LBYS_RS07220	COG1472	Belongs to the glycosyl hydrolase 3 family
LBYS_RS07270	COG0569	domain protein
LBYS_RS07275	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LBYS_RS07290	COG5000	phosphorelay sensor kinase activity
LBYS_RS07295	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LBYS_RS07300	COG1183	phosphatidylcholine synthase activity
LBYS_RS07305	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LBYS_RS07325	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LBYS_RS07335	COG1028	Short-chain dehydrogenase reductase Sdr
LBYS_RS07340	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LBYS_RS07345	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LBYS_RS07365	COG0644	oxidoreductase
LBYS_RS07375	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
LBYS_RS07435	COG0726	polysaccharide deacetylase
LBYS_RS07450	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LBYS_RS07480	COG0842	Transport permease protein
LBYS_RS07485	COG1131	(ABC) transporter
LBYS_RS07520	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LBYS_RS07545	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
LBYS_RS07555	COG0205	6-phosphofructokinase activity
LBYS_RS07570	COG1595	DNA-templated transcription, initiation
LBYS_RS07585	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LBYS_RS07590	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LBYS_RS07600	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LBYS_RS07605	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LBYS_RS07645	COG0306	phosphate transporter
LBYS_RS07650	COG0820	rRNA (adenine-C2-)-methyltransferase activity
LBYS_RS07685	COG0067	glutamate synthase
LBYS_RS07685	COG0070	glutamate synthase
LBYS_RS07685	COG0069	glutamate synthase activity
LBYS_RS07750	COG4585	Histidine kinase
LBYS_RS07755	COG2197	response regulator
LBYS_RS07760	COG4771	TonB-dependent receptor
LBYS_RS07770	COG0330	HflC and HflK could
LBYS_RS07785	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LBYS_RS07790	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LBYS_RS07800	COG0564	pseudouridine synthase activity
LBYS_RS07810	COG1028	Short-chain dehydrogenase reductase Sdr
LBYS_RS07830	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LBYS_RS07835	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LBYS_RS07840	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LBYS_RS07850	COG0039	L-malate dehydrogenase activity
LBYS_RS07860	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LBYS_RS07865	COG0154	amidase activity
LBYS_RS07870	COG0741	lytic transglycosylase activity
LBYS_RS07870	COG1388	LysM domain
LBYS_RS07875	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LBYS_RS07875	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LBYS_RS07885	COG0779	Required for maturation of 30S ribosomal subunits
LBYS_RS07890	COG2251	uridine kinase activity
LBYS_RS07890	COG0195	Participates in both transcription termination and antitermination
LBYS_RS07895	COG5180	pathogenesis
LBYS_RS07895	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LBYS_RS07905	COG1388	LysM domain
LBYS_RS07905	COG3942	CHAP domain
LBYS_RS07930	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
LBYS_RS07935	COG3842	ATPase activity
LBYS_RS07945	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LBYS_RS07955	COG0436	Aminotransferase
LBYS_RS07960	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
LBYS_RS07970	COG2304	oxidoreductase activity
LBYS_RS07985	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
LBYS_RS07990	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LBYS_RS07990	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LBYS_RS08015	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LBYS_RS08030	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LBYS_RS08035	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LBYS_RS08065	COG1904	glucuronate isomerase
LBYS_RS08070	COG2721	sulfolactate sulfo-lyase activity
LBYS_RS08075	COG0246	Mannitol dehydrogenase
LBYS_RS08085	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
LBYS_RS08110	COG4771	TonB-dependent receptor
LBYS_RS08115	COG0702	epimerase
LBYS_RS08125	COG2423	ornithine cyclodeaminase activity
LBYS_RS08145	COG0745	RESPONSE REGULATOR receiver
LBYS_RS08185	COG2755	lipolytic protein G-D-S-L family
LBYS_RS08190	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
LBYS_RS08195	COG1028	Short-chain dehydrogenase reductase Sdr
LBYS_RS08205	COG3033	Beta-eliminating lyase
LBYS_RS08215	COG0612	Peptidase, M16
LBYS_RS08225	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LBYS_RS08230	COG1024	Enoyl-CoA hydratase
LBYS_RS08235	COG1162	GTPase activity
LBYS_RS08245	COG0758	DNA mediated transformation
LBYS_RS08245	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LBYS_RS08250	COG0556	nucleotide-excision repair
LBYS_RS08270	COG1131	(ABC) transporter
LBYS_RS08275	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LBYS_RS08280	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LBYS_RS08280	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
LBYS_RS08285	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LBYS_RS08290	COG1078	dGTPase activity
LBYS_RS08300	COG1446	asparaginase
LBYS_RS08315	COG0802	atpase or kinase
LBYS_RS08325	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LBYS_RS08360	COG1595	DNA-templated transcription, initiation
LBYS_RS08370	COG0194	GDP metabolic process
LBYS_RS08375	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LBYS_RS08380	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
LBYS_RS08390	COG0416	fatty acid biosynthetic process
LBYS_RS08395	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LBYS_RS08405	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LBYS_RS08410	COG0511	ligase activity, forming carbon-carbon bonds
LBYS_RS08415	COG0439	Biotin carboxylase
LBYS_RS08430	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LBYS_RS08450	COG4974	Belongs to the 'phage' integrase family
LBYS_RS08460	COG0006	proline dipeptidase activity
LBYS_RS08470	COG1522	sequence-specific DNA binding
LBYS_RS08475	COG3525	Glycosyl hydrolase, family 20, catalytic domain
LBYS_RS08480	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LBYS_RS08480	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LBYS_RS08485	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LBYS_RS08495	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LBYS_RS08505	COG2715	membrane protein required for spore maturation
LBYS_RS08510	COG0018	arginyl-trna synthetase
LBYS_RS08515	COG1561	YicC-like family, N-terminal region
LBYS_RS08540	COG2197	response regulator
LBYS_RS08555	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LBYS_RS08560	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LBYS_RS08580	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LBYS_RS08605	COG3281	Trehalose synthase
LBYS_RS08615	COG0745	RESPONSE REGULATOR receiver
LBYS_RS08620	COG5002	protein histidine kinase activity
LBYS_RS08630	COG0628	permease
LBYS_RS08635	COG0805	protein transport
LBYS_RS08640	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LBYS_RS08665	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LBYS_RS08670	COG0719	Fe-S assembly protein
LBYS_RS08680	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LBYS_RS08690	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LBYS_RS08715	COG0799	negative regulation of ribosome biogenesis
LBYS_RS08720	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LBYS_RS08730	COG3408	Glycogen debranching enzyme
LBYS_RS08735	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LBYS_RS08740	COG0346	lactoylglutathione lyase activity
LBYS_RS08750	COG1215	transferase activity, transferring glycosyl groups
LBYS_RS08760	COG0183	Belongs to the thiolase family
LBYS_RS08765	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LBYS_RS08765	COG0318	PFAM AMP-dependent synthetase and ligase
LBYS_RS08770	COG4771	TonB-dependent receptor
LBYS_RS08795	COG0673	inositol 2-dehydrogenase activity
LBYS_RS08800	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LBYS_RS08815	COG1649	PFAM Uncharacterised BCR, COG1649
LBYS_RS08820	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LBYS_RS08825	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LBYS_RS08830	COG1012	belongs to the aldehyde dehydrogenase family
LBYS_RS08835	COG3938	Belongs to the proline racemase family
LBYS_RS08840	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LBYS_RS08865	COG2986	histidine ammonia-lyase
LBYS_RS08870	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
LBYS_RS08875	COG1228	amidohydrolase
LBYS_RS08885	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LBYS_RS08895	COG0730	response to heat
LBYS_RS08900	COG4771	TonB-dependent receptor
LBYS_RS08905	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LBYS_RS08920	COG0175	sulfate reduction
LBYS_RS08925	COG0175	sulfate reduction
LBYS_RS08935	COG5002	protein histidine kinase activity
LBYS_RS08940	COG0745	RESPONSE REGULATOR receiver
LBYS_RS08950	COG4993	Dehydrogenase
LBYS_RS08955	COG3344	reverse transcriptase
LBYS_RS08960	COG0203	ribosomal protein L17
LBYS_RS08965	COG0202	RNA polymerase activity
LBYS_RS08970	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LBYS_RS08975	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LBYS_RS08980	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LBYS_RS08985	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LBYS_RS08990	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LBYS_RS08995	COG0024	Methionine aminopeptidase
LBYS_RS09000	COG0201	protein transport
LBYS_RS09005	COG0200	Binds to the 23S rRNA
LBYS_RS09010	COG1841	ribosomal large subunit assembly
LBYS_RS09015	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LBYS_RS09020	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LBYS_RS09025	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LBYS_RS09030	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LBYS_RS09035	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LBYS_RS09040	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LBYS_RS09045	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LBYS_RS09050	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LBYS_RS09055	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LBYS_RS09060	COG0255	Belongs to the universal ribosomal protein uL29 family
LBYS_RS09065	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LBYS_RS09070	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LBYS_RS09075	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LBYS_RS09080	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LBYS_RS09085	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LBYS_RS09090	COG0089	rRNA binding
LBYS_RS09095	COG0088	Forms part of the polypeptide exit tunnel
LBYS_RS09100	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LBYS_RS09115	COG1228	amidohydrolase
LBYS_RS09150	COG1301	dicarboxylic acid transport
LBYS_RS09155	COG1760	l-serine dehydratase
LBYS_RS09190	COG1696	Membrane protein involved in D-alanine export
LBYS_RS09195	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LBYS_RS09205	COG2963	transposase activity
LBYS_RS09240	COG3275	phosphorelay sensor kinase activity
LBYS_RS09245	COG3279	Response regulator of the LytR AlgR family
LBYS_RS09270	COG0745	RESPONSE REGULATOR receiver
LBYS_RS09270	COG2205	protein histidine kinase activity
LBYS_RS09270	COG3292	Two component regulator propeller
LBYS_RS09275	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
LBYS_RS09290	COG1629	transport
LBYS_RS09305	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LBYS_RS09320	COG1629	transport
LBYS_RS09320	COG4206	TonB-dependent receptor
LBYS_RS09325	COG3685	Protein conserved in bacteria
LBYS_RS09335	COG2814	Major facilitator Superfamily
LBYS_RS09340	COG3344	reverse transcriptase
LBYS_RS09350	COG0628	permease
LBYS_RS09360	COG0823	Involved in the tonB-independent uptake of proteins
LBYS_RS09375	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LBYS_RS09380	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LBYS_RS09390	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LBYS_RS09405	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LBYS_RS09410	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
LBYS_RS09420	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
LBYS_RS09435	COG1418	mRNA catabolic process
LBYS_RS09450	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LBYS_RS09450	COG0072	phenylalanine-tRNA ligase activity
LBYS_RS09480	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LBYS_RS09485	COG0505	Belongs to the CarA family
LBYS_RS09505	COG4770	biotin carboxylase activity
LBYS_RS09515	COG0439	Biotin carboxylase
LBYS_RS09520	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LBYS_RS09520	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LBYS_RS09525	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LBYS_RS09530	COG2378	regulation of single-species biofilm formation
LBYS_RS09555	COG0738	Major facilitator superfamily
LBYS_RS09560	COG3254	rhamnose metabolic process
LBYS_RS09575	COG0357	Ribosomal RNA small subunit methyltransferase G
LBYS_RS09580	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LBYS_RS09585	COG5002	protein histidine kinase activity
LBYS_RS09590	COG0659	secondary active sulfate transmembrane transporter activity
LBYS_RS09595	COG0288	reversible hydration of carbon dioxide
LBYS_RS09600	COG0586	Pfam SNARE associated Golgi protein
LBYS_RS09605	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LBYS_RS09615	COG0049	tRNA binding
LBYS_RS09620	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LBYS_RS09625	COG1028	Short-chain dehydrogenase reductase Sdr
LBYS_RS09630	COG0179	Fumarylacetoacetate (FAA) hydrolase
LBYS_RS09660	COG0488	(ABC) transporter
LBYS_RS09680	COG2353	YceI-like domain
LBYS_RS09685	COG0673	inositol 2-dehydrogenase activity
LBYS_RS09690	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LBYS_RS09695	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LBYS_RS09700	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LBYS_RS09705	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LBYS_RS09720	COG0113	porphobilinogen synthase activity
LBYS_RS09730	COG1505	serine-type exopeptidase activity
LBYS_RS09740	COG1301	dicarboxylic acid transport
LBYS_RS09745	COG0823	Involved in the tonB-independent uptake of proteins
LBYS_RS09745	COG4946	Tricorn protease homolog
LBYS_RS09745	COG1506	peptidase
LBYS_RS09755	COG2963	transposase activity
LBYS_RS09770	COG1032	radical SAM domain protein
LBYS_RS09775	COG0159	tryptophan synthase activity
LBYS_RS09780	COG2234	aminopeptidase activity
LBYS_RS09815	COG4206	TonB-dependent receptor
LBYS_RS09820	COG4372	Transposase
LBYS_RS09845	COG4584	PFAM Integrase catalytic
LBYS_RS09870	COG4771	TonB-dependent receptor
LBYS_RS09910	COG1028	Short-chain dehydrogenase reductase Sdr
LBYS_RS09920	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LBYS_RS09930	COG3279	Response regulator of the LytR AlgR family
LBYS_RS09980	COG1629	transport
LBYS_RS09980	COG4206	TonB-dependent receptor
LBYS_RS09990	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
LBYS_RS09995	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
LBYS_RS09995	COG0662	Cupin 2, conserved barrel domain protein
LBYS_RS10000	COG0513	Belongs to the DEAD box helicase family
LBYS_RS10010	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
LBYS_RS10020	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LBYS_RS10025	COG3344	reverse transcriptase
LBYS_RS10040	COG1595	DNA-templated transcription, initiation
LBYS_RS10050	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LBYS_RS10065	COG1381	Involved in DNA repair and RecF pathway recombination
LBYS_RS10070	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
LBYS_RS10075	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LBYS_RS10105	COG1970	mechanosensitive ion channel activity
LBYS_RS10115	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LBYS_RS10125	COG1162	GTPase activity
LBYS_RS10130	COG0849	cell division
LBYS_RS10135	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LBYS_RS10170	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LBYS_RS10175	COG1053	succinate dehydrogenase
LBYS_RS10185	COG4771	TonB-dependent receptor
LBYS_RS10205	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LBYS_RS10210	COG0527	aspartate kinase activity
LBYS_RS10215	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
LBYS_RS10225	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LBYS_RS10230	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LBYS_RS10245	COG0149	triose-phosphate isomerase activity
LBYS_RS10250	COG0217	transcriptional regulatory protein
LBYS_RS10265	COG4771	TonB-dependent receptor
LBYS_RS10280	COG0861	Integral membrane protein TerC family
LBYS_RS10285	COG0358	DNA primase activity
LBYS_RS10290	COG1192	Involved in chromosome partitioning
LBYS_RS10295	COG1475	DNA binding
LBYS_RS10300	COG0187	DNA topoisomerase II activity
LBYS_RS10310	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LBYS_RS10320	COG0667	Aldo Keto reductase
LBYS_RS10330	COG0318	PFAM AMP-dependent synthetase and ligase
LBYS_RS10355	COG2205	protein histidine kinase activity
LBYS_RS10360	COG0745	RESPONSE REGULATOR receiver
LBYS_RS10365	COG1785	Belongs to the alkaline phosphatase family
LBYS_RS10370	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LBYS_RS10380	COG1272	protein, Hemolysin III
LBYS_RS10385	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LBYS_RS10390	COG4771	TonB-dependent receptor
LBYS_RS10440	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LBYS_RS10445	COG0305	Participates in initiation and elongation during chromosome replication
LBYS_RS10455	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LBYS_RS10465	COG1192	Involved in chromosome partitioning
LBYS_RS10495	COG4771	TonB-dependent receptor
LBYS_RS10505	COG0220	tRNA (guanine-N7-)-methyltransferase activity
LBYS_RS10505	COG1519	Transferase
LBYS_RS10515	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LBYS_RS10560	COG2205	protein histidine kinase activity
LBYS_RS10560	COG0745	RESPONSE REGULATOR receiver
LBYS_RS10560	COG3292	Two component regulator propeller
LBYS_RS10565	COG1629	transport
LBYS_RS10570	COG0702	epimerase
LBYS_RS10600	COG3158	transport of potassium into the cell
LBYS_RS10610	COG5002	protein histidine kinase activity
LBYS_RS10615	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LBYS_RS10655	COG0778	Nitroreductase
LBYS_RS10660	COG1733	regulation of RNA biosynthetic process
LBYS_RS10675	COG0860	N-Acetylmuramoyl-L-alanine amidase
LBYS_RS10700	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LBYS_RS10705	COG1119	ATPase activity
LBYS_RS10710	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
LBYS_RS10725	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LBYS_RS10735	COG3525	Glycosyl hydrolase, family 20, catalytic domain
LBYS_RS10745	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LBYS_RS10745	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LBYS_RS10760	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
LBYS_RS10765	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LBYS_RS10775	COG0363	glucosamine-6-phosphate deaminase activity
LBYS_RS10820	COG2264	protein methyltransferase activity
LBYS_RS10835	COG1752	Esterase of the alpha-beta hydrolase superfamily
LBYS_RS10840	COG0662	Cupin 2, conserved barrel domain protein
LBYS_RS10840	COG2207	Transcriptional regulator
LBYS_RS10845	COG0346	lactoylglutathione lyase activity
LBYS_RS10880	COG0437	4 iron, 4 sulfur cluster binding
LBYS_RS10890	COG2814	Major facilitator Superfamily
LBYS_RS10910	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LBYS_RS10920	COG0109	protoheme IX farnesyltransferase activity
LBYS_RS10925	COG1845	cytochrome c oxidase, subunit III
LBYS_RS10945	COG2322	membrane
LBYS_RS10995	COG1770	oligopeptidase
LBYS_RS11010	COG0606	chelatase, subunit chli
LBYS_RS11020	COG0606	chelatase, subunit chli
LBYS_RS11125	COG4372	Transposase
LBYS_RS11180	COG0606	chelatase, subunit chli
LBYS_RS11190	COG4771	TonB-dependent receptor
LBYS_RS11205	COG0584	glycerophosphoryl diester phosphodiesterase
LBYS_RS11210	COG0592	DNA-directed DNA polymerase activity
LBYS_RS11215	COG4124	Belongs to the glycosyl hydrolase 26 family
LBYS_RS11220	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
LBYS_RS11270	COG1629	transport
LBYS_RS11275	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LBYS_RS11280	COG0513	Belongs to the DEAD box helicase family
LBYS_RS11305	COG4771	TonB-dependent receptor
LBYS_RS11310	COG1609	Transcriptional regulator
LBYS_RS11315	COG0129	dihydroxy-acid dehydratase activity
LBYS_RS11320	COG0028	Belongs to the TPP enzyme family
LBYS_RS11325	COG0440	acetolactate synthase activity
LBYS_RS11330	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LBYS_RS11345	COG0137	argininosuccinate synthase activity
LBYS_RS11350	COG0501	Belongs to the peptidase M48B family
LBYS_RS11380	COG0688	phosphatidylethanolamine metabolic process
LBYS_RS11385	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LBYS_RS11400	COG0659	secondary active sulfate transmembrane transporter activity
LBYS_RS11445	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LBYS_RS11450	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LBYS_RS11470	COG4771	TonB-dependent receptor
LBYS_RS11475	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LBYS_RS11480	COG5479	isomerase activity
LBYS_RS11480	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
LBYS_RS11485	COG0366	Alpha amylase catalytic
LBYS_RS11505	COG1629	transport
LBYS_RS11505	COG4206	TonB-dependent receptor
LBYS_RS11515	COG4771	TonB-dependent receptor
LBYS_RS11520	COG1917	Cupin 2, conserved barrel domain protein
LBYS_RS11520	COG4977	sequence-specific DNA binding
LBYS_RS11540	COG4977	sequence-specific DNA binding
LBYS_RS11540	COG1917	Cupin 2, conserved barrel domain protein
LBYS_RS11545	COG0242	peptide deformylase activity
LBYS_RS11550	COG1609	Transcriptional regulator
LBYS_RS11555	COG4771	TonB-dependent receptor
LBYS_RS11570	COG2382	esterase
LBYS_RS11575	COG3507	Belongs to the glycosyl hydrolase 43 family
LBYS_RS11580	COG3507	Belongs to the glycosyl hydrolase 43 family
LBYS_RS11590	COG3661	Belongs to the glycosyl hydrolase 67 family
LBYS_RS11595	COG1028	Short-chain dehydrogenase reductase Sdr
LBYS_RS11610	COG2211	Major facilitator Superfamily
LBYS_RS11635	COG4585	Histidine kinase
LBYS_RS11640	COG2197	response regulator
LBYS_RS11655	COG4952	isomerase
LBYS_RS11660	COG3347	Dehydrogenase
LBYS_RS11660	COG1028	Short-chain dehydrogenase reductase Sdr
LBYS_RS11670	COG3250	beta-galactosidase activity
LBYS_RS11675	COG0583	DNA-binding transcription factor activity
LBYS_RS11680	COG1725	Transcriptional regulator
LBYS_RS11685	COG2824	Alkylphosphonate utilization operon protein PhnA
LBYS_RS11690	COG2311	Membrane
LBYS_RS11720	COG3254	rhamnose metabolic process
LBYS_RS11725	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
LBYS_RS11730	COG3401	FG-GAP repeat protein
LBYS_RS11740	COG1629	transport
LBYS_RS11745	COG0745	RESPONSE REGULATOR receiver
LBYS_RS11745	COG2205	protein histidine kinase activity
LBYS_RS11745	COG3292	Two component regulator propeller
LBYS_RS11750	COG4191	Histidine kinase
LBYS_RS11755	COG2204	response regulator
LBYS_RS11765	COG0577	efflux transmembrane transporter activity
LBYS_RS11765	COG1136	(ABC) transporter
LBYS_RS11770	COG1136	(ABC) transporter
LBYS_RS11780	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LBYS_RS11785	COG0571	ribonuclease III activity
LBYS_RS11790	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LBYS_RS11795	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LBYS_RS11800	COG2877	3-deoxy-8-phosphooctulonate synthase activity
LBYS_RS11805	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
LBYS_RS11810	COG0564	pseudouridine synthase activity
LBYS_RS11815	COG2873	o-acetylhomoserine
LBYS_RS11865	COG1566	PFAM secretion protein HlyD family protein
LBYS_RS11870	COG0552	protein localization to endoplasmic reticulum
LBYS_RS11880	COG0133	tryptophan synthase activity
LBYS_RS11885	COG0135	phosphoribosylanthranilate isomerase activity
LBYS_RS11890	COG0134	indole-3-glycerol-phosphate synthase activity
LBYS_RS11910	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LBYS_RS11920	COG1950	PFAM Membrane protein of
LBYS_RS11925	COG0140	phosphoribosyl-ATP diphosphatase activity
LBYS_RS11925	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LBYS_RS11940	COG3177	Filamentation induced by cAMP protein fic
LBYS_RS11975	COG2963	transposase activity
LBYS_RS12065	COG2963	transposase activity
LBYS_RS12150	COG1629	transport
LBYS_RS12150	COG4206	TonB-dependent receptor
LBYS_RS12205	COG1028	Short-chain dehydrogenase reductase Sdr
LBYS_RS12215	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
LBYS_RS12225	COG0463	Glycosyl transferase, family 2
LBYS_RS12240	COG0557	exoribonuclease II activity
LBYS_RS12265	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
LBYS_RS12270	COG0438	transferase activity, transferring glycosyl groups
LBYS_RS12285	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LBYS_RS12300	COG0110	maltose O-acetyltransferase activity
LBYS_RS12330	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LBYS_RS12360	COG0798	PFAM Bile acid sodium symporter
LBYS_RS12380	COG0793	Belongs to the peptidase S41A family
LBYS_RS12405	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LBYS_RS12410	COG0577	efflux transmembrane transporter activity
LBYS_RS12410	COG1136	(ABC) transporter
LBYS_RS12425	COG1525	nuclease
LBYS_RS12430	COG1137	ATPase activity
LBYS_RS12435	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
LBYS_RS12435	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LBYS_RS12440	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LBYS_RS12505	COG2160	L-arabinose isomerase activity
LBYS_RS12535	COG1082	Xylose isomerase domain protein TIM barrel
LBYS_RS12540	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
LBYS_RS12575	COG1595	DNA-templated transcription, initiation
LBYS_RS12615	COG4771	TonB-dependent receptor
LBYS_RS12620	COG0745	RESPONSE REGULATOR receiver
LBYS_RS12620	COG2205	protein histidine kinase activity
LBYS_RS12620	COG3292	Two component regulator propeller
LBYS_RS12645	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LBYS_RS12660	COG3279	Response regulator of the LytR AlgR family
LBYS_RS12670	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LBYS_RS12675	COG0525	valine-tRNA ligase activity
LBYS_RS12690	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LBYS_RS12695	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LBYS_RS12700	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LBYS_RS12705	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LBYS_RS12730	COG0404	The glycine cleavage system catalyzes the degradation of glycine
LBYS_RS12740	COG1678	Uncharacterized ACR, COG1678
LBYS_RS12745	COG1252	NADH dehydrogenase
LBYS_RS12750	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
LBYS_RS12755	COG2181	nitrate reductase activity
LBYS_RS12755	COG0247	lactate metabolic process
LBYS_RS12765	COG3311	Transcriptional regulator
LBYS_RS12770	COG1569	PIN domain
LBYS_RS12795	COG3344	reverse transcriptase
LBYS_RS12800	COG1538	Outer membrane efflux protein
LBYS_RS12810	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LBYS_RS12825	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LBYS_RS12835	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LBYS_RS12840	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LBYS_RS12855	COG0668	transmembrane transport
LBYS_RS12860	COG0539	negative regulation of cytoplasmic translation
LBYS_RS12865	COG0488	(ABC) transporter
LBYS_RS12875	COG1472	Belongs to the glycosyl hydrolase 3 family
LBYS_RS12880	COG1506	peptidase
LBYS_RS12915	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LBYS_RS12930	COG0445	tRNA wobble uridine modification
LBYS_RS12940	COG0708	Exodeoxyribonuclease III
LBYS_RS12950	COG1040	competence protein
LBYS_RS12965	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LBYS_RS12975	COG1752	Esterase of the alpha-beta hydrolase superfamily
LBYS_RS12990	COG4774	siderophore transport
LBYS_RS12995	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LBYS_RS13000	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LBYS_RS13010	COG1012	belongs to the aldehyde dehydrogenase family
LBYS_RS13020	COG1611	Belongs to the LOG family
LBYS_RS13025	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LBYS_RS13030	COG0081	regulation of translation
LBYS_RS13035	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LBYS_RS13040	COG0222	ribosome binding
LBYS_RS13070	COG0085	RNA polymerase activity
LBYS_RS13075	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LBYS_RS13080	COG3279	Response regulator of the LytR AlgR family
LBYS_RS13110	COG4771	TonB-dependent receptor
LBYS_RS13115	COG0477	Major facilitator Superfamily
LBYS_RS13125	COG0247	lactate metabolic process
LBYS_RS13125	COG0277	FAD linked oxidase domain protein
LBYS_RS13150	COG0436	Aminotransferase
LBYS_RS13155	COG0275	rRNA processing
LBYS_RS13165	COG0768	penicillin binding
LBYS_RS13185	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LBYS_RS13190	COG0071	Belongs to the small heat shock protein (HSP20) family
LBYS_RS13200	COG1960	acyl-CoA dehydrogenase activity
LBYS_RS13215	COG0463	Glycosyl transferase, family 2
LBYS_RS13235	COG0531	amino acid
LBYS_RS13240	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LBYS_RS13245	COG0697	spore germination
LBYS_RS13275	COG0726	polysaccharide deacetylase
LBYS_RS13290	COG0788	formyltetrahydrofolate deformylase activity
LBYS_RS13295	COG1160	GTP binding
LBYS_RS13305	COG1132	(ABC) transporter
LBYS_RS13315	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LBYS_RS13320	COG3250	beta-galactosidase activity
LBYS_RS13320	COG5297	Belongs to the glycosyl hydrolase family 6
LBYS_RS13325	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LBYS_RS13335	COG0545	Peptidyl-prolyl cis-trans isomerase
LBYS_RS13345	COG0473	3-isopropylmalate dehydrogenase activity
LBYS_RS13355	COG0066	3-isopropylmalate dehydratase activity
LBYS_RS13360	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LBYS_RS13380	COG0024	Methionine aminopeptidase
LBYS_RS13395	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LBYS_RS13400	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LBYS_RS13410	COG1309	transcriptional regulator
LBYS_RS13415	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LBYS_RS13420	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LBYS_RS13440	COG0544	peptidyl-prolyl cis-trans isomerase activity
LBYS_RS13450	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LBYS_RS13470	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LBYS_RS13485	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
LBYS_RS13500	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LBYS_RS13535	COG1131	(ABC) transporter
LBYS_RS13550	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LBYS_RS13555	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LBYS_RS13570	COG3142	Participates in the control of copper homeostasis
LBYS_RS13580	COG2226	methyltransferase
LBYS_RS13585	COG0167	dihydroorotate dehydrogenase activity
LBYS_RS13590	COG2860	membrane
LBYS_RS13620	COG0247	lactate metabolic process
LBYS_RS13620	COG2181	nitrate reductase activity
LBYS_RS13630	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LBYS_RS13645	COG2045	Belongs to the ComB family
LBYS_RS13675	COG0436	Aminotransferase
LBYS_RS13685	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LBYS_RS13690	COG2885	chlorophyll binding
LBYS_RS13695	COG0316	Belongs to the HesB IscA family
LBYS_RS13700	COG3876	Protein conserved in bacteria
LBYS_RS13715	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LBYS_RS13750	COG0348	domain, Protein
LBYS_RS13775	COG0492	ferredoxin-NADP+ reductase activity
LBYS_RS13795	COG0429	hydrolase of the alpha beta-hydrolase fold
LBYS_RS13800	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
LBYS_RS13805	COG1217	gtp-binding protein TYPA
LBYS_RS13810	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LBYS_RS13815	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LBYS_RS13820	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LBYS_RS13830	COG0156	8-amino-7-oxononanoate synthase activity
LBYS_RS13850	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LBYS_RS13855	COG1609	Transcriptional regulator
LBYS_RS13860	COG4771	TonB-dependent receptor
LBYS_RS13870	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LBYS_RS13875	COG0612	Peptidase, M16
LBYS_RS13885	COG1007	ATP synthesis coupled electron transport
LBYS_RS13890	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LBYS_RS13895	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LBYS_RS13900	COG0713	ATP synthesis coupled electron transport
LBYS_RS13910	COG3852	Histidine kinase
LBYS_RS13915	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LBYS_RS13920	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LBYS_RS13940	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LBYS_RS13950	COG0735	belongs to the Fur family
LBYS_RS13960	COG4771	TonB-dependent receptor
LBYS_RS13975	COG0596	Alpha beta hydrolase
LBYS_RS13980	COG1629	transport
LBYS_RS13980	COG4206	TonB-dependent receptor
LBYS_RS14030	COG0861	Integral membrane protein TerC family
LBYS_RS14040	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LBYS_RS14050	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
LBYS_RS14055	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LBYS_RS14070	COG1739	Uncharacterized protein family UPF0029
LBYS_RS14090	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LBYS_RS14100	COG1674	ftsk spoiiie
LBYS_RS14120	COG1024	Enoyl-CoA hydratase
LBYS_RS14120	COG1250	3-hydroxyacyl-CoA dehydrogenase
LBYS_RS14125	COG0183	Belongs to the thiolase family
LBYS_RS14135	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LBYS_RS14165	COG1595	DNA-templated transcription, initiation
LBYS_RS14170	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LBYS_RS14170	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LBYS_RS14175	COG0138	bifunctional purine biosynthesis protein purh
LBYS_RS14180	COG0531	amino acid
LBYS_RS14190	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LBYS_RS14195	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LBYS_RS14215	COG0513	Belongs to the DEAD box helicase family
LBYS_RS14225	COG1131	(ABC) transporter
LBYS_RS14240	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LBYS_RS14245	COG2363	Small membrane protein
LBYS_RS14255	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LBYS_RS14260	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LBYS_RS14265	COG0052	Belongs to the universal ribosomal protein uS2 family
LBYS_RS14270	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LBYS_RS14290	COG2255	four-way junction helicase activity
LBYS_RS14300	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LBYS_RS14330	COG1104	cysteine desulfurase activity
LBYS_RS14340	COG3279	Response regulator of the LytR AlgR family
LBYS_RS14355	COG3384	dioxygenase
LBYS_RS14360	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
LBYS_RS14365	COG0516	GMP reductase activity
LBYS_RS14365	COG0517	IMP dehydrogenase activity
LBYS_RS14370	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LBYS_RS14375	COG0215	cysteine-tRNA ligase activity
LBYS_RS14385	COG2706	6-phosphogluconolactonase activity
LBYS_RS14395	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
LBYS_RS14405	COG1956	GAF domain-containing protein
LBYS_RS14410	COG3956	TIGRFAM MazG family protein
LBYS_RS14420	COG0534	Mate efflux family protein
LBYS_RS14430	COG1408	metallophosphoesterase
LBYS_RS14440	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
LBYS_RS14465	COG1215	transferase activity, transferring glycosyl groups
LBYS_RS14470	COG0343	queuine tRNA-ribosyltransferase activity
LBYS_RS14475	COG0105	UTP biosynthetic process
LBYS_RS14490	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LBYS_RS14495	COG0398	Pfam SNARE associated Golgi protein
LBYS_RS14500	COG0232	Belongs to the dGTPase family. Type 2 subfamily
LBYS_RS14505	COG1983	PspC domain protein
LBYS_RS14530	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LBYS_RS14540	COG1960	acyl-CoA dehydrogenase activity
LBYS_RS14555	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LBYS_RS14560	COG0107	imidazoleglycerol-phosphate synthase activity
LBYS_RS14565	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LBYS_RS14570	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LBYS_RS14580	COG0165	Argininosuccinate lyase
LBYS_RS14605	COG1530	ribonuclease E activity
LBYS_RS14620	COG0242	peptide deformylase activity
LBYS_RS14625	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
LBYS_RS14640	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LBYS_RS14655	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LBYS_RS14665	COG1132	(ABC) transporter
LBYS_RS14675	COG0218	Necessary for normal cell division and for the maintenance of normal septation
LBYS_RS14695	COG1609	Transcriptional regulator
LBYS_RS14715	COG3292	Two component regulator propeller
LBYS_RS14715	COG0745	RESPONSE REGULATOR receiver
LBYS_RS14715	COG2205	protein histidine kinase activity
LBYS_RS14715	COG3292	Two component regulator propeller
LBYS_RS14715	COG0745	RESPONSE REGULATOR receiver
LBYS_RS14715	COG2205	protein histidine kinase activity
LBYS_RS14720	COG1501	Belongs to the glycosyl hydrolase 31 family
LBYS_RS14725	COG4206	TonB-dependent receptor
LBYS_RS14725	COG1629	transport
LBYS_RS14730	COG0702	epimerase
LBYS_RS14740	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
LBYS_RS14745	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LBYS_RS14750	COG3118	belongs to the thioredoxin family
LBYS_RS14755	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LBYS_RS14780	COG3279	Response regulator of the LytR AlgR family
LBYS_RS14795	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LBYS_RS14800	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LBYS_RS14805	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LBYS_RS14825	COG0475	glutathione-regulated potassium exporter activity
LBYS_RS14840	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LBYS_RS14845	COG1960	acyl-CoA dehydrogenase activity
LBYS_RS14850	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LBYS_RS14855	COG1024	Enoyl-CoA hydratase
LBYS_RS14860	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LBYS_RS14860	COG2111	Na H antiporter
LBYS_RS14870	COG1006	Multisubunit Na H antiporter MnhC subunit
LBYS_RS14875	COG0651	ATP synthesis coupled electron transport
LBYS_RS14880	COG1863	multisubunit Na H antiporter MnhE subunit
LBYS_RS14885	COG2212	antiporter activity
LBYS_RS14890	COG1320	monovalent cation:proton antiporter activity
LBYS_RS14915	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
LBYS_RS14930	COG4974	Belongs to the 'phage' integrase family
LBYS_RS14955	COG2197	response regulator
LBYS_RS14970	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LBYS_RS14980	COG0321	lipoyl(octanoyl) transferase activity
LBYS_RS14980	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LBYS_RS15010	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LBYS_RS15015	COG2304	oxidoreductase activity
LBYS_RS15020	COG0714	Associated with various cellular activities
LBYS_RS15025	COG2890	protein-(glutamine-N5) methyltransferase activity
LBYS_RS15040	COG0191	fructose-bisphosphate aldolase activity
LBYS_RS15045	COG4771	TonB-dependent receptor
LBYS_RS15050	COG0702	epimerase
LBYS_RS15060	COG0531	amino acid
LBYS_RS15080	COG0359	binds to the 23S rRNA
LBYS_RS15085	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LBYS_RS15090	COG0360	Binds together with S18 to 16S ribosomal RNA
LBYS_RS15100	COG0126	phosphoglycerate kinase activity
LBYS_RS15115	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LBYS_RS15120	COG0745	RESPONSE REGULATOR receiver
LBYS_RS15140	COG0470	DNA polymerase III
LBYS_RS15145	COG0488	(ABC) transporter
LBYS_RS15165	COG0442	prolyl-tRNA aminoacylation
LBYS_RS15170	COG1047	Peptidyl-prolyl cis-trans
LBYS_RS15175	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LBYS_RS15185	COG1193	negative regulation of DNA recombination
LBYS_RS15190	COG0393	Putative heavy-metal-binding
LBYS_RS15215	COG4772	TonB-dependent receptor
LBYS_RS15235	COG1607	acyl-coa hydrolase
LBYS_RS15245	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LBYS_RS15260	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LBYS_RS15265	COG4558	Periplasmic binding protein
LBYS_RS15270	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LBYS_RS15275	COG1120	ATPase activity
LBYS_RS15280	COG3720	iron ion transport
LBYS_RS15295	COG0405	Gamma-glutamyltransferase
LBYS_RS15330	COG0047	phosphoribosylformylglycinamidine synthase activity
LBYS_RS15335	COG0572	uridine kinase
LBYS_RS15345	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LBYS_RS15375	COG4221	oxidoreductase activity
LBYS_RS15380	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LBYS_RS15385	COG1127	ABC transporter
LBYS_RS15395	COG0792	nuclease activity
LBYS_RS15400	COG0321	lipoyl(octanoyl) transferase activity
LBYS_RS15405	COG4948	Mandelate Racemase Muconate Lactonizing
LBYS_RS15415	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LBYS_RS15430	COG1940	carbohydrate kinase activity
LBYS_RS15435	COG1929	Belongs to the glycerate kinase type-1 family
LBYS_RS15440	COG2267	carboxylic ester hydrolase activity
LBYS_RS15450	COG0528	UMP kinase activity
LBYS_RS15455	COG0233	cytoplasmic translational termination
LBYS_RS15510	COG1733	regulation of RNA biosynthetic process
LBYS_RS15515	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
LBYS_RS15525	COG2050	protein possibly involved in aromatic compounds catabolism
LBYS_RS15530	COG0406	alpha-ribazole phosphatase activity
LBYS_RS15535	COG3275	phosphorelay sensor kinase activity
LBYS_RS15540	COG3279	Response regulator of the LytR AlgR family
LBYS_RS15545	COG0823	Involved in the tonB-independent uptake of proteins
LBYS_RS15545	COG1506	peptidase
LBYS_RS15545	COG4946	Tricorn protease homolog
LBYS_RS15560	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LBYS_RS15575	COG3344	reverse transcriptase
LBYS_RS15600	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LBYS_RS15615	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LBYS_RS15635	COG0612	Peptidase, M16
LBYS_RS15655	COG1132	(ABC) transporter
LBYS_RS15665	COG2963	transposase activity
LBYS_RS15670	COG2801	Transposase and inactivated derivatives
LBYS_RS15675	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LBYS_RS15690	COG1012	belongs to the aldehyde dehydrogenase family
LBYS_RS15720	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LBYS_RS15720	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
LBYS_RS15740	COG0629	single-stranded DNA binding
LBYS_RS15765	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LBYS_RS15770	COG0586	Pfam SNARE associated Golgi protein
LBYS_RS15775	COG1809	phosphosulfolactate synthase activity
LBYS_RS15785	COG0616	signal peptide processing
LBYS_RS15820	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LBYS_RS15850	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LBYS_RS15855	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LBYS_RS15860	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LBYS_RS15875	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LBYS_RS15885	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
LBYS_RS15890	COG0017	Asparaginyl-tRNA synthetase
LBYS_RS15905	COG0288	reversible hydration of carbon dioxide
LBYS_RS15910	COG0326	Molecular chaperone. Has ATPase activity
LBYS_RS15915	COG1607	acyl-coa hydrolase
LBYS_RS15920	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LBYS_RS15925	COG2814	Major facilitator Superfamily
LBYS_RS15930	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LBYS_RS15955	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LBYS_RS15965	COG0702	epimerase
LBYS_RS15970	COG1959	2 iron, 2 sulfur cluster binding
LBYS_RS15980	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LBYS_RS15990	COG0297	glycogen (starch) synthase activity
LBYS_RS16000	COG0594	ribonuclease P activity
LBYS_RS16010	COG1214	PFAM Peptidase M22, glycoprotease
LBYS_RS16040	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LBYS_RS16045	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LBYS_RS16045	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LBYS_RS16060	COG0848	biopolymer transport protein
LBYS_RS16090	COG0563	adenylate kinase activity
LBYS_RS16095	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LBYS_RS16100	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LBYS_RS16105	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LBYS_RS16110	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LBYS_RS16115	COG0649	NAD binding
LBYS_RS16120	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
LBYS_RS16130	COG1034	ATP synthesis coupled electron transport
LBYS_RS16135	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
LBYS_RS16140	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LBYS_RS16145	COG0839	Belongs to the complex I subunit 6 family
LBYS_RS16160	COG4589	Belongs to the CDS family
LBYS_RS16175	COG0488	(ABC) transporter
LBYS_RS16180	COG2814	Major facilitator Superfamily
LBYS_RS16190	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LBYS_RS16195	COG4977	sequence-specific DNA binding
LBYS_RS16210	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LBYS_RS16245	COG1435	thymidine kinase activity
LBYS_RS16295	COG0811	peptide transport
LBYS_RS16305	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LBYS_RS16325	COG2205	protein histidine kinase activity
LBYS_RS16455	COG2963	transposase activity
LBYS_RS16475	COG3620	sequence-specific DNA binding
LBYS_RS16485	COG0358	DNA primase activity
LBYS_RS16510	COG0129	dihydroxy-acid dehydratase activity
LBYS_RS16515	COG2610	gluconate transmembrane transporter activity
LBYS_RS16520	COG0488	(ABC) transporter
LBYS_RS16535	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LBYS_RS16540	COG0069	glutamate synthase activity
LBYS_RS16565	COG1393	Belongs to the ArsC family
LBYS_RS16585	COG2996	Protein conserved in bacteria
LBYS_RS16590	COG0450	alkyl hydroperoxide reductase
LBYS_RS16595	COG0577	efflux transmembrane transporter activity
LBYS_RS16595	COG1136	(ABC) transporter
LBYS_RS16630	COG0433	COG0433 Predicted ATPase
LBYS_RS16650	COG0617	tRNA 3'-terminal CCA addition
LBYS_RS16650	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LBYS_RS16650	COG0517	IMP dehydrogenase activity
LBYS_RS16660	COG0284	orotidine-5'-phosphate decarboxylase activity
LBYS_RS16685	COG2814	Major facilitator Superfamily
LBYS_RS16690	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LBYS_RS16710	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LBYS_RS16715	COG1215	transferase activity, transferring glycosyl groups
LBYS_RS16720	COG0612	Peptidase, M16
LBYS_RS16745	COG1694	Mazg nucleotide pyrophosphohydrolase
LBYS_RS16750	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LBYS_RS16755	COG0051	transcription antitermination factor activity, RNA binding
LBYS_RS16770	COG0612	Peptidase, M16
LBYS_RS16785	COG1629	transport
LBYS_RS16795	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LBYS_RS16805	COG1774	PSP1 C-terminal conserved region
LBYS_RS16825	COG1187	pseudouridine synthase activity
LBYS_RS16835	COG2192	nodulation
LBYS_RS16860	COG1595	DNA-templated transcription, initiation
LBYS_RS16870	COG1629	transport
LBYS_RS16870	COG4206	TonB-dependent receptor
LBYS_RS16890	COG1609	Transcriptional regulator
LBYS_RS16890	COG2207	Transcriptional regulator
LBYS_RS16895	COG1082	Xylose isomerase domain protein TIM barrel
LBYS_RS16905	COG0166	Belongs to the GPI family
LBYS_RS16940	COG1007	ATP synthesis coupled electron transport
LBYS_RS16945	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LBYS_RS16955	COG0579	oxidoreductase
LBYS_RS16970	COG4221	oxidoreductase activity
LBYS_RS17015	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LBYS_RS17020	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LBYS_RS17025	COG0335	large ribosomal subunit rRNA binding
LBYS_RS17055	COG0346	lactoylglutathione lyase activity
LBYS_RS17065	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LBYS_RS17070	COG1138	Cytochrome C-type biogenesis protein
LBYS_RS17080	COG4206	TonB-dependent receptor
LBYS_RS17080	COG1629	transport
LBYS_RS17090	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LBYS_RS17095	COG0653	protein targeting
LBYS_RS17100	COG2207	Transcriptional regulator
LBYS_RS17105	COG4771	TonB-dependent receptor
LBYS_RS17110	COG0561	phosphatase activity
LBYS_RS17120	COG4124	Belongs to the glycosyl hydrolase 26 family
LBYS_RS17130	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
LBYS_RS17135	COG2942	2-epimerase
LBYS_RS17145	COG3743	rRNA binding
LBYS_RS17145	COG0261	This protein binds to 23S rRNA in the presence of protein L20
LBYS_RS17150	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
LBYS_RS17160	COG0545	Peptidyl-prolyl cis-trans isomerase
LBYS_RS17165	COG0793	Belongs to the peptidase S41A family
LBYS_RS17170	COG0531	amino acid
LBYS_RS17195	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LBYS_RS17210	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LBYS_RS17220	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LBYS_RS17250	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LBYS_RS17255	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LBYS_RS17260	COG0156	8-amino-7-oxononanoate synthase activity
LBYS_RS17285	COG0023	Translation Initiation Factor
LBYS_RS17295	COG1668	transmembrane transport
LBYS_RS17300	COG4152	abc transporter atp-binding protein
LBYS_RS17315	COG0012	GTP binding
LBYS_RS17350	COG0714	Associated with various cellular activities
LBYS_RS17375	COG5000	phosphorelay sensor kinase activity
LBYS_RS17380	COG1074	ATP-dependent DNA helicase activity
LBYS_RS17390	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
LBYS_RS17425	COG0508	dehydrogenase complex catalyzes the overall conversion of
LBYS_RS17430	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LBYS_RS17440	COG2311	Membrane
LBYS_RS17480	COG0583	DNA-binding transcription factor activity
LBYS_RS17485	COG3185	4-Hydroxyphenylpyruvate dioxygenase
LBYS_RS17490	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
LBYS_RS17500	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LBYS_RS17510	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LBYS_RS17515	COG0463	Glycosyl transferase, family 2
LBYS_RS17525	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
LBYS_RS17530	COG1610	YqeY-like protein
LBYS_RS17550	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LBYS_RS17555	COG1234	tRNA 3'-trailer cleavage
LBYS_RS17565	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LBYS_RS17580	COG1312	Catalyzes the dehydration of D-mannonate
LBYS_RS17615	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LBYS_RS17630	COG0667	Aldo Keto reductase
LBYS_RS17635	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LBYS_RS17660	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
LBYS_RS17665	COG3341	Caulimovirus viroplasmin
LBYS_RS17665	COG0328	RNA-DNA hybrid ribonuclease activity
LBYS_RS17670	COG1181	Belongs to the D-alanine--D-alanine ligase family
LBYS_RS17675	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
LBYS_RS17695	COG0489	protein tyrosine kinase activity
LBYS_RS17730	COG0826	peptidase U32
LBYS_RS17740	COG1137	ATPase activity
LBYS_RS17745	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LBYS_RS17795	COG1595	DNA-templated transcription, initiation
LBYS_RS17805	COG2217	Heavy metal translocating P-type atpase
LBYS_RS17820	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LBYS_RS17850	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LBYS_RS17870	COG0339	signal peptide processing
LBYS_RS17885	COG1546	Belongs to the CinA family
LBYS_RS17885	COG1058	Belongs to the CinA family
LBYS_RS17900	COG1404	Belongs to the peptidase S8 family
LBYS_RS17905	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
LBYS_RS17910	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LBYS_RS17920	COG1764	response to oxidative stress
LBYS_RS17935	COG0183	Belongs to the thiolase family
LBYS_RS17950	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LBYS_RS17955	COG2217	Heavy metal translocating P-type atpase
LBYS_RS18000	COG0596	Alpha beta hydrolase
LBYS_RS18015	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LBYS_RS18020	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LBYS_RS18025	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LBYS_RS18030	COG0356	it plays a direct role in the translocation of protons across the membrane
LBYS_RS18070	COG0732	type I restriction modification DNA specificity domain
LBYS_RS18090	COG1215	transferase activity, transferring glycosyl groups
LBYS_RS18100	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LBYS_RS18125	COG2801	Transposase and inactivated derivatives
LBYS_RS18145	COG3275	phosphorelay sensor kinase activity
LBYS_RS18155	COG0517	IMP dehydrogenase activity
LBYS_RS18160	COG0657	acetylesterase activity
LBYS_RS18280	COG1401	restriction endodeoxyribonuclease activity
LBYS_RS18295	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LBYS_RS18330	COG0529	Catalyzes the synthesis of activated sulfate
LBYS_RS18350	COG0577	efflux transmembrane transporter activity
LBYS_RS18350	COG1136	(ABC) transporter
LBYS_RS18370	COG1442	glycosyl transferase family 8
LBYS_RS18370	COG1216	Glycosyl transferase, family 2
LBYS_RS18375	COG4771	TonB-dependent receptor
LBYS_RS18380	COG4771	TonB-dependent receptor
LBYS_RS18400	COG3291	Pkd domain containing protein
LBYS_RS18410	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LBYS_RS18435	COG3275	phosphorelay sensor kinase activity
LBYS_RS18465	COG3275	phosphorelay sensor kinase activity
LBYS_RS18475	COG3599	regulation of cell shape