locus-tag	class	description
E4T55_RS00010	COG0183	Belongs to the thiolase family
E4T55_RS00065	COG0174	glutamine synthetase
E4T55_RS00085	COG2198	Histidine kinase
E4T55_RS00085	COG2205	protein histidine kinase activity
E4T55_RS00085	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E4T55_RS00085	COG0784	Response regulator, receiver
E4T55_RS00095	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
E4T55_RS00105	COG0673	inositol 2-dehydrogenase activity
E4T55_RS00115	COG0772	Belongs to the SEDS family
E4T55_RS00120	COG0768	penicillin binding
E4T55_RS00135	COG2132	Multicopper oxidase
E4T55_RS00145	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E4T55_RS00155	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
E4T55_RS00175	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
E4T55_RS00205	COG0482	sulfurtransferase activity
E4T55_RS00225	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
E4T55_RS00230	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
E4T55_RS00240	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
E4T55_RS00250	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
E4T55_RS00260	COG0470	DNA polymerase III
E4T55_RS00270	COG0084	hydrolase, TatD family'
E4T55_RS00275	COG2814	Major facilitator Superfamily
E4T55_RS00285	COG2814	Major facilitator Superfamily
E4T55_RS00305	COG4974	Belongs to the 'phage' integrase family
E4T55_RS00325	COG2433	Pfam Transposase IS66
E4T55_RS00330	COG3436	PFAM IS66 Orf2 family protein
E4T55_RS00350	COG0494	nUDIX hydrolase
E4T55_RS00380	COG0572	uridine kinase
E4T55_RS00405	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
E4T55_RS00405	COG3264	Mechanosensitive ion channel
E4T55_RS00410	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
E4T55_RS00435	COG0156	8-amino-7-oxononanoate synthase activity
E4T55_RS00450	COG4943	cyclic-guanylate-specific phosphodiesterase activity
E4T55_RS00480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
E4T55_RS00485	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
E4T55_RS00495	COG0436	Aminotransferase
E4T55_RS00515	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
E4T55_RS00570	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
E4T55_RS00575	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
E4T55_RS00580	COG0180	Tryptophanyl-tRNA synthetase
E4T55_RS00585	COG0009	L-threonylcarbamoyladenylate synthase
E4T55_RS00590	COG0613	PHP domain protein
E4T55_RS00595	COG1702	phosphate starvation-inducible protein PhoH
E4T55_RS00610	COG0745	RESPONSE REGULATOR receiver
E4T55_RS00615	COG2205	protein histidine kinase activity
E4T55_RS00620	COG0295	cytidine deaminase activity
E4T55_RS00625	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
E4T55_RS00630	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
E4T55_RS00675	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
E4T55_RS00690	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
E4T55_RS00700	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
E4T55_RS00715	COG0372	Belongs to the citrate synthase family
E4T55_RS00730	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
E4T55_RS00770	COG0456	acetyltransferase
E4T55_RS00775	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
E4T55_RS00780	COG0508	dehydrogenase complex catalyzes the overall conversion of
E4T55_RS00790	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
E4T55_RS00825	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
E4T55_RS00830	COG0850	regulation of cytokinetic process
E4T55_RS00835	COG0318	PFAM AMP-dependent synthetase and ligase
E4T55_RS00850	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
E4T55_RS00855	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
E4T55_RS00875	COG3138	arginine N-succinyltransferase
E4T55_RS00945	COG2894	cell division
E4T55_RS00955	COG1960	acyl-CoA dehydrogenase activity
E4T55_RS00960	COG2267	carboxylic ester hydrolase activity
E4T55_RS00970	COG3842	ATPase activity
E4T55_RS00975	COG0395	ABC-type sugar transport system, permease component
E4T55_RS00985	COG0038	chloride channel
E4T55_RS00990	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
E4T55_RS00990	COG0512	Glutamine amidotransferase of anthranilate synthase
E4T55_RS00995	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
E4T55_RS01020	COG0316	Belongs to the HesB IscA family
E4T55_RS01030	COG1104	cysteine desulfurase activity
E4T55_RS01080	COG0616	signal peptide processing
E4T55_RS01080	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
E4T55_RS01085	COG0542	response to heat
E4T55_RS01095	COG1335	isochorismatase
E4T55_RS01100	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
E4T55_RS01110	COG2814	Major facilitator Superfamily
E4T55_RS01115	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E4T55_RS01130	COG0800	Aldolase
E4T55_RS01140	COG0129	dihydroxy-acid dehydratase activity
E4T55_RS01150	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
E4T55_RS01165	COG1793	dna ligase
E4T55_RS01165	COG3285	dna ligase
E4T55_RS01195	COG2515	1-aminocyclopropane-1-carboxylate deaminase
E4T55_RS01200	COG4232	protein-disulfide reductase activity
E4T55_RS01210	COG0625	glutathione transferase activity
E4T55_RS01220	COG2801	Transposase and inactivated derivatives
E4T55_RS01245	COG2801	Transposase and inactivated derivatives
E4T55_RS01260	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
E4T55_RS01265	COG0159	tryptophan synthase activity
E4T55_RS01285	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
E4T55_RS01290	COG1686	Belongs to the peptidase S11 family
E4T55_RS01295	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
E4T55_RS01300	COG2921	Belongs to the UPF0250 family
E4T55_RS01310	COG0586	Pfam SNARE associated Golgi protein
E4T55_RS01320	COG3034	peptidoglycan biosynthetic process
E4T55_RS01325	COG5433	transposase activity
E4T55_RS01335	COG5433	transposase activity
E4T55_RS01370	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
E4T55_RS01385	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
E4T55_RS01395	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
E4T55_RS01415	COG2079	MmgE PrpD family protein
E4T55_RS01420	COG0372	Belongs to the citrate synthase family
E4T55_RS01425	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
E4T55_RS01470	COG1981	membrane
E4T55_RS01475	COG0861	Integral membrane protein TerC family
E4T55_RS01480	COG0617	tRNA 3'-terminal CCA addition
E4T55_RS01485	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
E4T55_RS01490	COG0589	response to stress
E4T55_RS01495	COG0471	metal ion transport
E4T55_RS01495	COG3273	potassium ion transport
E4T55_RS01510	COG2976	Protein conserved in bacteria
E4T55_RS01520	COG1426	Protein conserved in bacteria
E4T55_RS01535	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
E4T55_RS01555	COG0741	lytic transglycosylase activity
E4T55_RS01555	COG1388	LysM domain
E4T55_RS01560	COG2917	probably involved in intracellular septation
E4T55_RS01570	COG0642	Histidine kinase
E4T55_RS01590	COG0217	transcriptional regulatory protein
E4T55_RS01620	COG1388	LysM domain
E4T55_RS01620	COG4942	peptidase
E4T55_RS01625	COG1238	metal cluster binding
E4T55_RS01640	COG0281	malic enzyme
E4T55_RS01665	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
E4T55_RS01675	COG1024	Enoyl-CoA hydratase
E4T55_RS01675	COG1250	3-hydroxyacyl-CoA dehydrogenase
E4T55_RS01680	COG0183	Belongs to the thiolase family
E4T55_RS01735	COG3708	Transcriptional regulator
E4T55_RS01735	COG2207	Transcriptional regulator
E4T55_RS01750	COG5001	Diguanylate cyclase
E4T55_RS01750	COG3300	MHYT domain
E4T55_RS01765	COG0346	lactoylglutathione lyase activity
E4T55_RS01785	COG2066	Belongs to the glutaminase family
E4T55_RS01810	COG0739	heme binding
E4T55_RS01825	COG3842	ATPase activity
E4T55_RS01830	COG1176	ABC-type spermidine putrescine transport system, permease component I
E4T55_RS01835	COG1177	transmembrane transport
E4T55_RS01850	COG0463	Glycosyl transferase, family 2
E4T55_RS01855	COG0542	response to heat
E4T55_RS01870	COG1187	pseudouridine synthase activity
E4T55_RS01875	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
E4T55_RS01880	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
E4T55_RS01885	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
E4T55_RS01890	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
E4T55_RS01905	COG1792	Involved in formation and maintenance of cell shape
E4T55_RS01910	COG1077	Cell shape determining protein MreB Mrl
E4T55_RS01920	COG1555	photosystem II stabilization
E4T55_RS01925	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
E4T55_RS01940	COG0475	glutathione-regulated potassium exporter activity
E4T55_RS01960	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
E4T55_RS02030	COG2801	Transposase and inactivated derivatives
E4T55_RS02040	COG2433	Pfam Transposase IS66
E4T55_RS02045	COG3436	PFAM IS66 Orf2 family protein
E4T55_RS02060	COG2223	nitrite transmembrane transporter activity
E4T55_RS02065	COG0545	Peptidyl-prolyl cis-trans isomerase
E4T55_RS02070	COG1760	l-serine dehydratase
E4T55_RS02075	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
E4T55_RS02080	COG5433	transposase activity
E4T55_RS02095	COG1960	acyl-CoA dehydrogenase activity
E4T55_RS02100	COG5433	transposase activity
E4T55_RS02120	COG2801	Transposase and inactivated derivatives
E4T55_RS02160	COG5433	transposase activity
E4T55_RS02170	COG0733	neurotransmitter:sodium symporter activity
E4T55_RS02220	COG0154	amidase activity
E4T55_RS02235	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E4T55_RS02255	COG4221	oxidoreductase activity
E4T55_RS02285	COG1331	Highly conserved protein containing a thioredoxin domain
E4T55_RS02295	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
E4T55_RS02320	COG0585	pseudouridine synthase activity
E4T55_RS02330	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E4T55_RS02335	COG0601	transmembrane transport
E4T55_RS02345	COG1902	pentaerythritol trinitrate reductase activity
E4T55_RS02350	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
E4T55_RS02375	COG2814	Major facilitator Superfamily
E4T55_RS02395	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
E4T55_RS02395	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
E4T55_RS02430	COG0312	modulator of DNA gyrase
E4T55_RS02435	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
E4T55_RS02460	COG2911	Protein conserved in bacteria
E4T55_RS02465	COG0113	porphobilinogen synthase activity
E4T55_RS02480	COG0527	aspartate kinase activity
E4T55_RS02485	COG1074	ATP-dependent DNA helicase activity
E4T55_RS02490	COG0489	protein tyrosine kinase activity
E4T55_RS02535	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
E4T55_RS02550	COG1960	acyl-CoA dehydrogenase activity
E4T55_RS02555	COG0183	Belongs to the thiolase family
E4T55_RS02565	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
E4T55_RS02585	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
E4T55_RS02605	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
E4T55_RS02610	COG2011	ABC-type metal ion transport system permease component
E4T55_RS02635	COG0751	glycine-tRNA ligase activity
E4T55_RS02650	COG0210	DNA helicase
E4T55_RS02660	COG2853	Lipoprotein
E4T55_RS02665	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
E4T55_RS02670	COG0189	ligase activity
E4T55_RS02710	COG0572	uridine kinase
E4T55_RS02720	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
E4T55_RS02740	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
E4T55_RS02785	COG0488	(ABC) transporter
E4T55_RS02805	COG0681	Belongs to the peptidase S26 family
E4T55_RS02820	COG2951	lytic endotransglycosylase activity
E4T55_RS02845	COG0232	Belongs to the dGTPase family. Type 2 subfamily
E4T55_RS02880	COG1297	OPT oligopeptide transporter protein
E4T55_RS02920	COG0488	(ABC) transporter
E4T55_RS02930	COG0156	8-amino-7-oxononanoate synthase activity
E4T55_RS02935	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
E4T55_RS02940	COG1538	Outer membrane efflux protein
E4T55_RS02955	COG0659	secondary active sulfate transmembrane transporter activity
E4T55_RS02960	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
E4T55_RS02995	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
E4T55_RS03005	COG0477	Major facilitator Superfamily
E4T55_RS03035	COG1028	Short-chain dehydrogenase reductase Sdr
E4T55_RS03070	COG0142	geranyltranstransferase activity
E4T55_RS03075	COG2226	methyltransferase
E4T55_RS03080	COG1040	competence protein
E4T55_RS03085	COG0750	zinc metalloprotease
E4T55_RS03115	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
E4T55_RS03120	COG1519	Transferase
E4T55_RS03125	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
E4T55_RS03130	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
E4T55_RS03140	COG0505	Belongs to the CarA family
E4T55_RS03160	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
E4T55_RS03165	COG0429	hydrolase of the alpha beta-hydrolase fold
E4T55_RS03230	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E4T55_RS03235	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E4T55_RS03240	COG0628	permease
E4T55_RS03255	COG0482	sulfurtransferase activity
E4T55_RS03265	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
E4T55_RS03300	COG0602	queuosine metabolic process
E4T55_RS03305	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
E4T55_RS03310	COG2885	chlorophyll binding
E4T55_RS03315	COG3218	ABC-type transport auxiliary lipoprotein component
E4T55_RS03325	COG1127	ABC transporter
E4T55_RS03330	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
E4T55_RS03335	COG1301	dicarboxylic acid transport
E4T55_RS03340	COG5310	Homospermidine synthase
E4T55_RS03405	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
E4T55_RS03440	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
E4T55_RS03500	COG5433	transposase activity
E4T55_RS03525	COG2801	Transposase and inactivated derivatives
E4T55_RS03535	COG3344	reverse transcriptase
E4T55_RS03540	COG5433	transposase activity
E4T55_RS03545	COG5433	transposase activity
E4T55_RS03575	COG1307	EDD domain protein, DegV family
E4T55_RS03600	COG2363	Small membrane protein
E4T55_RS03605	COG0515	serine threonine protein kinase
E4T55_RS03605	COG2815	serine threonine protein kinase
E4T55_RS03615	COG2814	Major facilitator Superfamily
E4T55_RS03640	COG5433	transposase activity
E4T55_RS03645	COG5433	transposase activity
E4T55_RS03670	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
E4T55_RS03675	COG2801	Transposase and inactivated derivatives
E4T55_RS03700	COG2433	Pfam Transposase IS66
E4T55_RS03705	COG3436	PFAM IS66 Orf2 family protein
E4T55_RS03730	COG2433	Pfam Transposase IS66
E4T55_RS03735	COG3436	PFAM IS66 Orf2 family protein
E4T55_RS03755	COG5433	transposase activity
E4T55_RS03770	COG2801	Transposase and inactivated derivatives
E4T55_RS03810	COG2801	Transposase and inactivated derivatives
E4T55_RS03855	COG1132	(ABC) transporter
E4T55_RS03860	COG0583	DNA-binding transcription factor activity
E4T55_RS03865	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
E4T55_RS03875	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
E4T55_RS03900	COG0415	Belongs to the DNA photolyase family
E4T55_RS03920	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E4T55_RS03925	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
E4T55_RS03950	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
E4T55_RS03950	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
E4T55_RS03970	COG0628	permease
E4T55_RS03975	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
E4T55_RS03980	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
E4T55_RS04000	COG2823	Periplasmic or secreted lipoprotein
E4T55_RS04015	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E4T55_RS04020	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E4T55_RS04035	COG3012	SEC-C Motif Domain Protein
E4T55_RS04040	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
E4T55_RS04050	COG0205	6-phosphofructokinase activity
E4T55_RS04055	COG4969	Belongs to the N-Me-Phe pilin family
E4T55_RS04065	COG0271	Belongs to the BolA IbaG family
E4T55_RS04075	COG0531	amino acid
E4T55_RS04100	COG1214	PFAM Peptidase M22, glycoprotease
E4T55_RS04105	COG1199	ATP-dependent helicase activity
E4T55_RS04110	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
E4T55_RS04125	COG2313	pseudouridylate synthase activity
E4T55_RS04150	COG2337	Toxic component of a toxin-antitoxin (TA) module
E4T55_RS04190	COG2801	Transposase and inactivated derivatives
E4T55_RS04240	COG2801	Transposase and inactivated derivatives
E4T55_RS04265	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E4T55_RS04280	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
E4T55_RS04280	COG0456	acetyltransferase
E4T55_RS04285	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
E4T55_RS04285	COG0140	phosphoribosyl-ATP diphosphatase activity
E4T55_RS04290	COG0107	imidazoleglycerol-phosphate synthase activity
E4T55_RS04315	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
E4T55_RS04320	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
E4T55_RS04330	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
E4T55_RS04355	COG0288	reversible hydration of carbon dioxide
E4T55_RS04415	COG0028	Belongs to the TPP enzyme family
E4T55_RS04440	COG1446	asparaginase
E4T55_RS04485	COG2197	response regulator
E4T55_RS04505	COG4221	oxidoreductase activity
E4T55_RS04550	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
E4T55_RS04550	COG0473	3-isopropylmalate dehydrogenase activity
E4T55_RS04565	COG1181	Belongs to the D-alanine--D-alanine ligase family
E4T55_RS04565	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
E4T55_RS04660	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E4T55_RS04665	COG3189	MarR family transcriptional regulator
E4T55_RS04670	COG1881	PFAM PEBP family protein
E4T55_RS04675	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
E4T55_RS04685	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
E4T55_RS04745	COG3264	Mechanosensitive ion channel
E4T55_RS04745	COG1196	nuclear chromosome segregation
E4T55_RS04760	COG2239	Acts as a magnesium transporter
E4T55_RS04765	COG1028	Short-chain dehydrogenase reductase Sdr
E4T55_RS04775	COG1475	DNA binding
E4T55_RS04780	COG2027	D-alanyl-D-alanine carboxypeptidase
E4T55_RS04810	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
E4T55_RS04820	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
E4T55_RS04840	COG0772	Belongs to the SEDS family
E4T55_RS04850	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
E4T55_RS04855	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
E4T55_RS04860	COG3115	cell septum assembly
E4T55_RS04865	COG1196	nuclear chromosome segregation
E4T55_RS04870	COG3243	poly(R)-hydroxyalkanoic acid synthase
E4T55_RS04880	COG0398	Pfam SNARE associated Golgi protein
E4T55_RS04895	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
E4T55_RS04905	COG0347	Belongs to the P(II) protein family
E4T55_RS04910	COG2960	long-chain fatty acid transporting porin activity
E4T55_RS04915	COG0606	chelatase, subunit chli
E4T55_RS04925	COG0756	dUTP diphosphatase activity
E4T55_RS04930	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
E4T55_RS04935	COG2003	Belongs to the UPF0758 family
E4T55_RS04950	COG2151	metal-sulfur cluster biosynthetic enzyme
E4T55_RS04955	COG0822	iron-sulfur transferase activity
E4T55_RS04960	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
E4T55_RS04965	COG0719	Fe-S assembly protein
E4T55_RS04970	COG0396	ATPase activity
E4T55_RS04975	COG0719	Fe-S assembly protein
E4T55_RS04980	COG1959	2 iron, 2 sulfur cluster binding
E4T55_RS05005	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
E4T55_RS05015	COG0795	lipopolysaccharide-transporting ATPase activity
E4T55_RS05020	COG0795	lipopolysaccharide-transporting ATPase activity
E4T55_RS05050	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
E4T55_RS05095	COG3300	MHYT domain
E4T55_RS05095	COG5001	Diguanylate cyclase
E4T55_RS05100	COG5433	transposase activity
E4T55_RS05115	COG0322	excinuclease ABC activity
E4T55_RS05120	COG2197	response regulator
E4T55_RS05135	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E4T55_RS05150	COG1546	Belongs to the CinA family
E4T55_RS05150	COG1058	Belongs to the CinA family
E4T55_RS05155	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
E4T55_RS05180	COG0012	GTP binding
E4T55_RS05185	COG0142	geranyltranstransferase activity
E4T55_RS05205	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
E4T55_RS05215	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
E4T55_RS05235	COG0575	Belongs to the CDS family
E4T55_RS05275	COG2177	Part of the ABC transporter FtsEX involved in
E4T55_RS05280	COG2884	Cell division ATP-binding protein ftsE
E4T55_RS05285	COG0552	protein localization to endoplasmic reticulum
E4T55_RS05290	COG0612	Peptidase, M16
E4T55_RS05300	COG0742	ribosomal rna small subunit methyltransferase
E4T55_RS05340	COG0859	PFAM glycosyl transferase family 9
E4T55_RS05355	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
E4T55_RS05360	COG0860	N-Acetylmuramoyl-L-alanine amidase
E4T55_RS05365	COG0802	atpase or kinase
E4T55_RS05370	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
E4T55_RS05370	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
E4T55_RS05375	COG2969	positive regulation of protein catabolic process
E4T55_RS05380	COG0625	glutathione transferase activity
E4T55_RS05385	COG2857	Cytochrome c1
E4T55_RS05390	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
E4T55_RS05395	COG0723	plastoquinol--plastocyanin reductase activity
E4T55_RS05415	COG0330	HflC and HflK could
E4T55_RS05420	COG0330	HflC and HflK could
E4T55_RS05430	COG1363	Peptidase, m42
E4T55_RS05450	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
E4T55_RS05460	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E4T55_RS05460	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E4T55_RS05460	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E4T55_RS05470	COG1183	phosphatidylcholine synthase activity
E4T55_RS05495	COG3588	fructose-bisphosphate aldolase
E4T55_RS05500	COG3568	Endonuclease Exonuclease Phosphatase
E4T55_RS05515	COG3227	Zinc metalloprotease (Elastase)
E4T55_RS05525	COG4106	trans-aconitate 2-methyltransferase activity
E4T55_RS05540	COG5016	pyruvate
E4T55_RS05540	COG0511	ligase activity, forming carbon-carbon bonds
E4T55_RS05550	COG0511	ligase activity, forming carbon-carbon bonds
E4T55_RS05555	COG0439	Biotin carboxylase
E4T55_RS05580	COG5433	transposase activity
E4T55_RS05685	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
E4T55_RS05690	COG0537	adenosine 5'-monophosphoramidase activity
E4T55_RS05695	COG0302	gtp cyclohydrolase
E4T55_RS05700	COG1185	polyribonucleotide nucleotidyltransferase activity
E4T55_RS05710	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
E4T55_RS05725	COG0195	Participates in both transcription termination and antitermination
E4T55_RS05775	COG1034	ATP synthesis coupled electron transport
E4T55_RS05780	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
E4T55_RS05805	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
E4T55_RS05820	COG0149	triose-phosphate isomerase activity
E4T55_RS05835	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
E4T55_RS05840	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
E4T55_RS05885	COG0776	regulation of translation
E4T55_RS05895	COG0735	belongs to the Fur family
E4T55_RS05900	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E4T55_RS05920	COG2914	Belongs to the UPF0125 (RnfH) family
E4T55_RS05935	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
E4T55_RS05945	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
E4T55_RS05955	COG0730	response to heat
E4T55_RS05960	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
E4T55_RS05970	COG0252	asparaginase activity
E4T55_RS05985	COG0598	Magnesium transport protein CorA
E4T55_RS05995	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
E4T55_RS06000	COG2878	Part of a membrane complex involved in electron transport
E4T55_RS06015	COG1475	DNA binding
E4T55_RS06020	COG1192	Involved in chromosome partitioning
E4T55_RS06025	COG0357	Ribosomal RNA small subunit methyltransferase G
E4T55_RS06055	COG0662	Cupin 2, conserved barrel domain protein
E4T55_RS06055	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
E4T55_RS06060	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
E4T55_RS06065	COG1845	cytochrome c oxidase, subunit III
E4T55_RS06080	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
E4T55_RS06085	COG1529	Aldehyde oxidase and xanthine dehydrogenase
E4T55_RS06085	COG2010	Cytochrome c
E4T55_RS06110	COG0477	Major facilitator Superfamily
E4T55_RS06125	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
E4T55_RS06140	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
E4T55_RS06150	COG2814	Major facilitator Superfamily
E4T55_RS06160	COG1028	Short-chain dehydrogenase reductase Sdr
E4T55_RS06165	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
E4T55_RS06170	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
E4T55_RS06175	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
E4T55_RS06180	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
E4T55_RS06185	COG1560	Kdo2-lipid A biosynthetic process
E4T55_RS06210	COG0577	efflux transmembrane transporter activity
E4T55_RS06210	COG1136	(ABC) transporter
E4T55_RS06215	COG1136	(ABC) transporter
E4T55_RS06220	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E4T55_RS06230	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
E4T55_RS06240	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
E4T55_RS06245	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
E4T55_RS06275	COG0714	Associated with various cellular activities
E4T55_RS06290	COG2304	oxidoreductase activity
E4T55_RS06315	COG0659	secondary active sulfate transmembrane transporter activity
E4T55_RS06320	COG1278	Cold shock
E4T55_RS06345	COG0516	GMP reductase activity
E4T55_RS06350	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
E4T55_RS06355	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
E4T55_RS06365	COG1054	Belongs to the UPF0176 family
E4T55_RS06370	COG3240	lipase activity
E4T55_RS06380	COG2183	response to ionizing radiation
E4T55_RS06395	COG0497	DNA recombination
E4T55_RS06405	COG1217	gtp-binding protein TYPA
E4T55_RS06410	COG0629	single-stranded DNA binding
E4T55_RS06480	COG3791	Glutathione-dependent formaldehyde-activating
E4T55_RS06530	COG3436	PFAM IS66 Orf2 family protein
E4T55_RS06535	COG2433	Pfam Transposase IS66
E4T55_RS06550	COG0300	oxidoreductase activity
E4T55_RS06555	COG0456	acetyltransferase
E4T55_RS06565	COG5433	transposase activity
E4T55_RS06595	COG1253	flavin adenine dinucleotide binding
E4T55_RS06600	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
E4T55_RS06605	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
E4T55_RS06605	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
E4T55_RS06610	COG0456	acetyltransferase
E4T55_RS06610	COG0454	-acetyltransferase
E4T55_RS06620	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
E4T55_RS06645	COG0501	Belongs to the peptidase M48B family
E4T55_RS06650	COG1704	LemA family
E4T55_RS06655	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
E4T55_RS06675	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
E4T55_RS06680	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
E4T55_RS06685	COG0557	exoribonuclease II activity
E4T55_RS06695	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E4T55_RS06720	COG0531	amino acid
E4T55_RS06730	COG0697	spore germination
E4T55_RS06745	COG3028	Belongs to the UPF0307 family
E4T55_RS06755	COG3240	lipase activity
E4T55_RS06765	COG2095	MarC family integral membrane protein
E4T55_RS06775	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E4T55_RS06795	COG0123	including yeast histone deacetylase and acetoin utilization protein
E4T55_RS06850	COG5433	transposase activity
E4T55_RS06930	COG5433	transposase activity
E4T55_RS06945	COG2801	Transposase and inactivated derivatives
E4T55_RS06955	COG0582	viral genome integration into host DNA
E4T55_RS06960	COG3550	peptidyl-serine autophosphorylation
E4T55_RS06965	COG1396	sequence-specific DNA binding
E4T55_RS06990	COG0629	single-stranded DNA binding
E4T55_RS07005	COG0582	viral genome integration into host DNA
E4T55_RS07090	COG0436	Aminotransferase
E4T55_RS07095	COG0556	nucleotide-excision repair
E4T55_RS07120	COG3079	Belongs to the UPF0149 family
E4T55_RS07125	COG0006	proline dipeptidase activity
E4T55_RS07130	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E4T55_RS07135	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E4T55_RS07150	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
E4T55_RS07165	COG0330	HflC and HflK could
E4T55_RS07170	COG0433	COG0433 Predicted ATPase
E4T55_RS07180	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
E4T55_RS07190	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
E4T55_RS07210	COG0418	dihydroorotase activity
E4T55_RS07215	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
E4T55_RS07220	COG0450	alkyl hydroperoxide reductase
E4T55_RS07225	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
E4T55_RS07230	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
E4T55_RS07235	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
E4T55_RS07260	COG0071	Belongs to the small heat shock protein (HSP20) family
E4T55_RS07280	COG0477	Major facilitator Superfamily
E4T55_RS07290	COG3227	Zinc metalloprotease (Elastase)
E4T55_RS07355	COG2823	Periplasmic or secreted lipoprotein
E4T55_RS07360	COG2823	Periplasmic or secreted lipoprotein
E4T55_RS07365	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
E4T55_RS07370	COG0792	nuclease activity
E4T55_RS07380	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
E4T55_RS07430	COG0592	DNA-directed DNA polymerase activity
E4T55_RS07435	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
E4T55_RS07440	COG0187	DNA topoisomerase II activity
E4T55_RS07465	COG0488	(ABC) transporter
E4T55_RS07470	COG0659	secondary active sulfate transmembrane transporter activity
E4T55_RS07500	COG0628	permease
E4T55_RS07540	COG0697	spore germination
E4T55_RS07580	COG5433	transposase activity
E4T55_RS07595	COG3436	PFAM IS66 Orf2 family protein
E4T55_RS07600	COG2433	Pfam Transposase IS66
E4T55_RS07635	COG3293	Transposase
E4T55_RS07650	COG2827	Endonuclease containing a URI domain
E4T55_RS07685	COG2801	Transposase and inactivated derivatives
E4T55_RS07755	COG2801	Transposase and inactivated derivatives
E4T55_RS07785	COG0582	viral genome integration into host DNA
E4T55_RS07795	COG0582	viral genome integration into host DNA
E4T55_RS07820	COG0242	peptide deformylase activity
E4T55_RS07825	COG0477	Major facilitator Superfamily
E4T55_RS07860	COG1872	DUF167
E4T55_RS07865	COG2824	Alkylphosphonate utilization operon protein PhnA
E4T55_RS07870	COG0659	secondary active sulfate transmembrane transporter activity
E4T55_RS07895	COG3846	protein secretion by the type IV secretion system
E4T55_RS07930	COG3451	type IV secretory pathway VirB4
E4T55_RS07935	COG5268	conjugation
E4T55_RS07945	COG4962	Type ii secretion system protein e
E4T55_RS07950	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
E4T55_RS07980	COG4974	Belongs to the 'phage' integrase family
E4T55_RS07990	COG5433	transposase activity
E4T55_RS08005	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
E4T55_RS08045	COG0604	alcohol dehydrogenase
E4T55_RS08050	COG0339	signal peptide processing
E4T55_RS08070	COG5433	transposase activity
E4T55_RS08075	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
E4T55_RS08080	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
E4T55_RS08090	COG0469	pyruvate kinase activity
E4T55_RS08160	COG1573	uracil-dna glycosylase
E4T55_RS08180	COG1215	transferase activity, transferring glycosyl groups
E4T55_RS08200	COG0655	NAD(P)H dehydrogenase (quinone) activity
E4T55_RS08205	COG0435	Glutathione S-transferase
E4T55_RS08220	COG4221	oxidoreductase activity
E4T55_RS08225	COG1666	GTP binding
E4T55_RS08255	COG3360	Dodecin
E4T55_RS08270	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
E4T55_RS08285	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
E4T55_RS08290	COG1116	anion transmembrane transporter activity
E4T55_RS08320	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
E4T55_RS08375	COG1509	lysine 2,3-aminomutase activity
E4T55_RS08390	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
E4T55_RS08395	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
E4T55_RS08410	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
E4T55_RS08460	COG4067	protein conserved in archaea
E4T55_RS08460	COG0189	ligase activity
E4T55_RS08465	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
E4T55_RS08470	COG3178	'Phosphotransferase
E4T55_RS08485	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
E4T55_RS08490	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
E4T55_RS08545	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
E4T55_RS08570	COG0222	ribosome binding
E4T55_RS08745	COG0604	alcohol dehydrogenase
E4T55_RS08760	COG1671	Belongs to the UPF0178 family
E4T55_RS08780	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
E4T55_RS08785	COG0210	DNA helicase
E4T55_RS08840	COG2719	SpoVR family
E4T55_RS08850	COG2766	serine protein kinase
E4T55_RS08855	COG0308	aminopeptidase N
E4T55_RS08880	COG3104	oligopeptide transport
E4T55_RS08900	COG0300	oxidoreductase activity
E4T55_RS08905	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
E4T55_RS08910	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E4T55_RS08935	COG2135	peptidase activity
E4T55_RS08940	COG2135	peptidase activity
E4T55_RS08950	COG4974	Belongs to the 'phage' integrase family
E4T55_RS08965	COG5433	transposase activity
E4T55_RS08980	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
E4T55_RS08985	COG2814	Major facilitator Superfamily
E4T55_RS08990	COG2814	Major facilitator Superfamily
E4T55_RS08995	COG4264	IucA IucC family
E4T55_RS09000	COG0114	fumarate hydratase activity
E4T55_RS09005	COG1385	rRNA (uridine-N3-)-methyltransferase activity
E4T55_RS09025	COG0543	2 iron, 2 sulfur cluster binding
E4T55_RS09025	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
E4T55_RS09045	COG0805	protein transport
E4T55_RS09080	COG0569	domain protein
E4T55_RS09085	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
E4T55_RS09095	COG0842	Transport permease protein
E4T55_RS09100	COG1131	(ABC) transporter
E4T55_RS09115	COG3153	acetyltransferase
E4T55_RS09115	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
E4T55_RS09130	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E4T55_RS09135	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
E4T55_RS09150	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
E4T55_RS09160	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
E4T55_RS09165	COG1228	amidohydrolase
E4T55_RS09170	COG0531	amino acid
E4T55_RS09205	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
E4T55_RS09210	COG0741	lytic transglycosylase activity
E4T55_RS09220	COG1218	3'(2'),5'-bisphosphate nucleotidase
E4T55_RS09225	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
E4T55_RS09235	COG1653	transport
E4T55_RS09240	COG0584	glycerophosphoryl diester phosphodiesterase
E4T55_RS09270	COG0625	glutathione transferase activity
E4T55_RS09320	COG2815	serine threonine protein kinase
E4T55_RS09320	COG0515	serine threonine protein kinase
E4T55_RS09345	COG1612	heme a metabolic process
E4T55_RS09385	COG1278	Cold shock
E4T55_RS09390	COG4536	flavin adenine dinucleotide binding
E4T55_RS09395	COG0745	RESPONSE REGULATOR receiver
E4T55_RS09420	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
E4T55_RS09425	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
E4T55_RS09495	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
E4T55_RS09530	COG1271	oxidase subunit
E4T55_RS09535	COG1294	oxidase, subunit
E4T55_RS09540	COG0745	RESPONSE REGULATOR receiver
E4T55_RS09560	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
E4T55_RS09565	COG2860	membrane
E4T55_RS09580	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
E4T55_RS09625	COG0776	regulation of translation
E4T55_RS09640	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
E4T55_RS09665	COG1234	tRNA 3'-trailer cleavage
E4T55_RS09670	COG4689	acetoacetate decarboxylase
E4T55_RS09675	COG1252	NADH dehydrogenase
E4T55_RS09685	COG0793	Belongs to the peptidase S41A family
E4T55_RS09690	COG4942	peptidase
E4T55_RS09700	COG0439	Biotin carboxylase
E4T55_RS09710	COG3932	Exopolysaccharide synthesis, ExoD
E4T55_RS09755	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
E4T55_RS09785	COG2009	succinate dehydrogenase
E4T55_RS09790	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
E4T55_RS09795	COG1053	succinate dehydrogenase
E4T55_RS09800	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
E4T55_RS09820	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
E4T55_RS09840	COG2814	Major facilitator Superfamily
E4T55_RS09845	COG0668	transmembrane transport
E4T55_RS09855	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
E4T55_RS09860	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
E4T55_RS09870	COG0393	Putative heavy-metal-binding
E4T55_RS09875	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
E4T55_RS09895	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
E4T55_RS09915	COG4232	protein-disulfide reductase activity
E4T55_RS09945	COG0783	Belongs to the Dps family
E4T55_RS09960	COG4172	Belongs to the ABC transporter superfamily
E4T55_RS09980	COG1960	acyl-CoA dehydrogenase activity
E4T55_RS10010	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
E4T55_RS10065	COG2814	Major facilitator Superfamily
E4T55_RS10080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E4T55_RS10105	COG0814	amino acid
E4T55_RS10110	COG0165	Argininosuccinate lyase
E4T55_RS10115	COG0137	argininosuccinate synthase activity
E4T55_RS10120	COG1438	arginine binding
E4T55_RS10130	COG2050	protein possibly involved in aromatic compounds catabolism
E4T55_RS10135	COG5433	transposase activity
E4T55_RS10145	COG3475	LICD family
E4T55_RS10160	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
E4T55_RS10170	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
E4T55_RS10185	COG1193	negative regulation of DNA recombination
E4T55_RS10200	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
E4T55_RS10245	COG0546	phosphoglycolate phosphatase activity
E4T55_RS10250	COG0564	pseudouridine synthase activity
E4T55_RS10255	COG1530	ribonuclease E activity
E4T55_RS10280	COG0281	malic enzyme
E4T55_RS10285	COG0583	DNA-binding transcription factor activity
E4T55_RS10290	COG0450	alkyl hydroperoxide reductase
E4T55_RS10365	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
E4T55_RS10370	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
E4T55_RS10375	COG0242	peptide deformylase activity
E4T55_RS10385	COG0758	DNA mediated transformation
E4T55_RS10425	COG0708	Exodeoxyribonuclease III
E4T55_RS10430	COG0708	Exodeoxyribonuclease III
E4T55_RS10440	COG0281	malic enzyme
E4T55_RS10445	COG2223	nitrite transmembrane transporter activity
E4T55_RS10455	COG0338	D12 class N6 adenine-specific DNA methyltransferase
E4T55_RS10465	COG0651	ATP synthesis coupled electron transport
E4T55_RS10470	COG1006	Multisubunit Na H antiporter MnhC subunit
E4T55_RS10475	COG2111	Na H antiporter
E4T55_RS10480	COG2111	Na H antiporter
E4T55_RS10480	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
E4T55_RS10490	COG0589	response to stress
E4T55_RS10495	COG1863	multisubunit Na H antiporter MnhE subunit
E4T55_RS10505	COG1320	monovalent cation:proton antiporter activity
E4T55_RS10520	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
E4T55_RS10520	COG2010	Cytochrome c
E4T55_RS10525	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
E4T55_RS10535	COG0861	Integral membrane protein TerC family
E4T55_RS10560	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
E4T55_RS10570	COG2271	Major facilitator Superfamily
E4T55_RS10605	COG3273	potassium ion transport
E4T55_RS10605	COG0471	metal ion transport
E4T55_RS10615	COG2340	Cysteine-rich secretory protein family
E4T55_RS10635	COG0519	Catalyzes the synthesis of GMP from XMP
E4T55_RS10685	COG1971	Probably functions as a manganese efflux pump
E4T55_RS10690	COG0833	amino acid
E4T55_RS10715	COG3220	belongs to the UPF0276 family
E4T55_RS10770	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
E4T55_RS10775	COG0398	Pfam SNARE associated Golgi protein
E4T55_RS10795	COG3615	Tellurite resistance protein tehB
E4T55_RS10795	COG0500	methyltransferase
E4T55_RS10815	COG0659	secondary active sulfate transmembrane transporter activity
E4T55_RS10825	COG4651	solute:proton antiporter activity
E4T55_RS10825	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
E4T55_RS10830	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
E4T55_RS10835	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
E4T55_RS10840	COG0280	phosphate acetyltransferase
E4T55_RS10855	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
E4T55_RS10870	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
E4T55_RS10875	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
E4T55_RS10890	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
E4T55_RS10905	COG0309	Hydrogenase expression formation protein (HypE)
E4T55_RS10920	COG1941	NADH ubiquinone oxidoreductase 20 kDa subunit
E4T55_RS10940	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
E4T55_RS10945	COG2391	methyltransferase activity
E4T55_RS10960	COG0701	Predicted permease
E4T55_RS10965	COG2132	Multicopper oxidase
E4T55_RS10970	COG0778	Nitroreductase
E4T55_RS10975	COG2124	cytochrome p450
E4T55_RS10985	COG2346	COG2346, Truncated hemoglobins
E4T55_RS10990	COG1959	2 iron, 2 sulfur cluster binding
E4T55_RS10995	COG3189	MarR family transcriptional regulator
E4T55_RS11000	COG3615	Tellurite resistance protein tehB
E4T55_RS11000	COG0500	methyltransferase
E4T55_RS11005	COG2259	Doxx family
E4T55_RS11015	COG0477	Major facilitator Superfamily
E4T55_RS11030	COG0629	single-stranded DNA binding
E4T55_RS11190	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
E4T55_RS11210	COG0280	phosphate acetyltransferase
E4T55_RS11220	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
E4T55_RS11230	COG4651	solute:proton antiporter activity
E4T55_RS11230	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
E4T55_RS11245	COG0589	response to stress
E4T55_RS11250	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
E4T55_RS11260	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
E4T55_RS11290	COG0534	Mate efflux family protein
E4T55_RS11345	COG0604	alcohol dehydrogenase
E4T55_RS11345	COG3321	synthase
E4T55_RS11350	COG1028	Short-chain dehydrogenase reductase Sdr
E4T55_RS11350	COG0300	oxidoreductase activity
E4T55_RS11350	COG0318	PFAM AMP-dependent synthetase and ligase
E4T55_RS11350	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
E4T55_RS11350	COG3321	synthase
E4T55_RS11355	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
E4T55_RS11375	COG1363	Peptidase, m42
E4T55_RS11380	COG5433	transposase activity
E4T55_RS11405	COG0657	acetylesterase activity
E4T55_RS11415	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
E4T55_RS11420	COG2801	Transposase and inactivated derivatives
E4T55_RS11445	COG0513	Belongs to the DEAD box helicase family
E4T55_RS11450	COG0583	DNA-binding transcription factor activity
E4T55_RS11465	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E4T55_RS11475	COG0589	response to stress
E4T55_RS11495	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
E4T55_RS11505	COG4890	Cyd operon protein YbgT
E4T55_RS11510	COG1294	oxidase, subunit
E4T55_RS11555	COG1959	2 iron, 2 sulfur cluster binding
E4T55_RS11560	COG2346	COG2346, Truncated hemoglobins
E4T55_RS11570	COG2124	cytochrome p450
E4T55_RS11575	COG0778	Nitroreductase
E4T55_RS11590	COG1522	sequence-specific DNA binding
E4T55_RS11600	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
E4T55_RS11605	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
E4T55_RS11610	COG0066	3-isopropylmalate dehydratase activity
E4T55_RS11615	COG0473	3-isopropylmalate dehydrogenase activity
E4T55_RS11630	COG1280	lysine exporter protein (LysE YggA)
E4T55_RS11645	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
E4T55_RS11655	COG4175	Glycine betaine
E4T55_RS11655	COG0517	IMP dehydrogenase activity
E4T55_RS11660	COG4176	ABC-type proline glycine betaine transport system permease component
E4T55_RS11700	COG1090	epimerase
E4T55_RS11720	COG2801	Transposase and inactivated derivatives
E4T55_RS11725	COG0784	Response regulator, receiver
E4T55_RS11725	COG4191	Histidine kinase
E4T55_RS11730	COG4251	negative regulation of phosphorylation
E4T55_RS11735	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
E4T55_RS11740	COG3328	transposase activity
E4T55_RS11745	COG2433	Pfam Transposase IS66
E4T55_RS11750	COG3436	PFAM IS66 Orf2 family protein
E4T55_RS11800	COG2801	Transposase and inactivated derivatives
E4T55_RS11825	COG0589	response to stress
E4T55_RS11830	COG0435	Glutathione S-transferase
E4T55_RS11855	COG3436	PFAM IS66 Orf2 family protein
E4T55_RS11860	COG2433	Pfam Transposase IS66
E4T55_RS11890	COG2801	Transposase and inactivated derivatives
E4T55_RS11895	COG3189	MarR family transcriptional regulator
E4T55_RS11900	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
E4T55_RS11905	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
E4T55_RS11920	COG1959	2 iron, 2 sulfur cluster binding
E4T55_RS11925	COG2346	COG2346, Truncated hemoglobins
E4T55_RS11935	COG2801	Transposase and inactivated derivatives
E4T55_RS12000	COG3436	PFAM IS66 Orf2 family protein
E4T55_RS12005	COG2433	Pfam Transposase IS66
E4T55_RS12045	COG0629	single-stranded DNA binding
E4T55_RS12085	COG3550	peptidyl-serine autophosphorylation
E4T55_RS12090	COG3550	peptidyl-serine autophosphorylation
E4T55_RS12100	COG0778	Nitroreductase
E4T55_RS12125	COG0629	single-stranded DNA binding
E4T55_RS12140	COG3655	Transcriptional regulator
E4T55_RS12180	COG0358	DNA primase activity
E4T55_RS12185	COG1610	YqeY-like protein
E4T55_RS12205	COG0635	Involved in the biosynthesis of porphyrin-containing compound
E4T55_RS12210	COG0494	nUDIX hydrolase
E4T55_RS12220	COG2032	superoxide dismutase activity
E4T55_RS12225	COG0697	spore germination
E4T55_RS12230	COG0697	spore germination
E4T55_RS12235	COG1902	pentaerythritol trinitrate reductase activity
E4T55_RS12235	COG0446	pyridine nucleotide-disulphide oxidoreductase
E4T55_RS12240	COG1597	lipid kinase activity
E4T55_RS12255	COG0534	Mate efflux family protein
E4T55_RS12300	COG5001	Diguanylate cyclase
E4T55_RS12300	COG5002	protein histidine kinase activity
E4T55_RS12305	COG1392	Phosphate transport regulator
E4T55_RS12310	COG0306	phosphate transporter
E4T55_RS12315	COG2199	diguanylate cyclase activity
E4T55_RS12315	COG2203	Gaf domain
E4T55_RS12320	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E4T55_RS12325	COG1131	(ABC) transporter
E4T55_RS12330	COG0842	Transport permease protein
E4T55_RS12340	COG0814	amino acid
E4T55_RS12350	COG0513	Belongs to the DEAD box helicase family
E4T55_RS12355	COG2226	methyltransferase
E4T55_RS12360	COG2153	protein acetylation
E4T55_RS12375	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
E4T55_RS12380	COG1028	Short-chain dehydrogenase reductase Sdr
E4T55_RS12385	COG1028	Short-chain dehydrogenase reductase Sdr
E4T55_RS12390	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
E4T55_RS12405	COG2715	membrane protein required for spore maturation
E4T55_RS12410	COG0700	Nucleoside recognition
E4T55_RS12450	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
E4T55_RS12455	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
E4T55_RS12460	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
E4T55_RS12470	COG0814	amino acid
E4T55_RS12480	COG0814	amino acid
E4T55_RS12495	COG1090	epimerase
E4T55_RS12515	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E4T55_RS12520	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E4T55_RS12530	COG4876	unkown
E4T55_RS12550	COG0477	Major facilitator Superfamily
E4T55_RS12565	COG0762	integral membrane protein
E4T55_RS12590	COG1561	YicC-like family, N-terminal region
E4T55_RS12605	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
E4T55_RS12615	COG3577	Aspartyl protease
E4T55_RS12620	COG0488	(ABC) transporter
E4T55_RS12640	COG0343	queuine tRNA-ribosyltransferase activity
E4T55_RS12645	COG1862	Preprotein translocase
E4T55_RS12650	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
E4T55_RS12655	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
E4T55_RS12715	COG0492	ferredoxin-NADP+ reductase activity
E4T55_RS12730	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
E4T55_RS12770	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
E4T55_RS12775	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E4T55_RS12790	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
E4T55_RS12815	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
E4T55_RS12835	COG0305	Participates in initiation and elongation during chromosome replication
E4T55_RS12870	COG4106	trans-aconitate 2-methyltransferase activity
E4T55_RS12880	COG1088	dTDP-glucose 4,6-dehydratase activity
E4T55_RS12890	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
E4T55_RS12925	COG1215	transferase activity, transferring glycosyl groups
E4T55_RS12960	COG0730	response to heat
E4T55_RS12965	COG1218	3'(2'),5'-bisphosphate nucleotidase
E4T55_RS12975	COG0175	sulfate reduction
E4T55_RS12985	COG1215	transferase activity, transferring glycosyl groups
E4T55_RS12985	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
E4T55_RS13025	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
E4T55_RS13030	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
E4T55_RS13035	COG0463	Glycosyl transferase, family 2
E4T55_RS13035	COG1216	Glycosyl transferase, family 2
E4T55_RS13070	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
E4T55_RS13090	COG1846	Transcriptional regulator
E4T55_RS13095	COG0582	viral genome integration into host DNA
E4T55_RS13120	COG1598	PFAM Uncharacterised protein family UPF0150
E4T55_RS13205	COG4974	Belongs to the 'phage' integrase family
E4T55_RS13245	COG2944	sequence-specific DNA binding
E4T55_RS13260	COG5433	transposase activity
E4T55_RS13300	COG2801	Transposase and inactivated derivatives
E4T55_RS13315	COG0512	Glutamine amidotransferase of anthranilate synthase
E4T55_RS13330	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
E4T55_RS13340	COG5007	Belongs to the BolA IbaG family
E4T55_RS13360	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
E4T55_RS13365	COG1127	ABC transporter
E4T55_RS13375	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
E4T55_RS13390	COG1137	ATPase activity
E4T55_RS13395	COG2890	protein-(glutamine-N5) methyltransferase activity
E4T55_RS13405	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
E4T55_RS13420	COG1295	ribonuclease BN
E4T55_RS13430	COG0616	signal peptide processing
E4T55_RS13460	COG1138	Cytochrome C-type biogenesis protein
E4T55_RS13480	COG3360	Dodecin
E4T55_RS13490	COG0514	ATP-dependent DNA helicase (RecQ)
E4T55_RS13500	COG1024	Enoyl-CoA hydratase
E4T55_RS13540	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
E4T55_RS13560	COG1472	Belongs to the glycosyl hydrolase 3 family
E4T55_RS13565	COG1301	dicarboxylic acid transport
E4T55_RS13590	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
E4T55_RS13615	COG0626	cystathionine gamma-synthase activity
E4T55_RS13655	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
E4T55_RS13700	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
E4T55_RS13765	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
E4T55_RS13775	COG1994	Peptidase M50
E4T55_RS13800	COG0686	Belongs to the AlaDH PNT family
E4T55_RS13810	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
E4T55_RS13810	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
E4T55_RS13815	COG0307	riboflavin synthase, alpha
E4T55_RS13820	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
E4T55_RS13820	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
E4T55_RS13830	COG5285	phytanoyl-CoA dioxygenase
E4T55_RS13855	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E4T55_RS13865	COG2974	May be involved in recombination
E4T55_RS13875	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
E4T55_RS13880	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
E4T55_RS13880	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
E4T55_RS13890	COG0312	modulator of DNA gyrase
E4T55_RS13915	COG0492	ferredoxin-NADP+ reductase activity
E4T55_RS13920	COG1674	ftsk spoiiie
E4T55_RS13930	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
E4T55_RS13965	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
E4T55_RS14000	COG1012	belongs to the aldehyde dehydrogenase family
E4T55_RS14005	COG2271	Major facilitator Superfamily
E4T55_RS14030	COG1042	CoA-binding domain protein
E4T55_RS14030	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E4T55_RS14030	COG0045	succinate-CoA ligase (ADP-forming) activity
E4T55_RS14065	COG3190	flagellar
E4T55_RS14065	COG1338	Plays a role in the flagellum-specific transport system
E4T55_RS14070	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
E4T55_RS14090	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
E4T55_RS14105	COG1157	protein secretion by the type III secretion system
E4T55_RS14135	COG1766	The M ring may be actively involved in energy transduction
E4T55_RS14140	COG1677	Flagellar hook-basal body complex protein FliE
E4T55_RS14145	COG1558	bacterial-type flagellum-dependent cell motility
E4T55_RS14155	COG1706	bacterial-type flagellum-dependent cell motility
E4T55_RS14160	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
E4T55_RS14170	COG4786	Flagellar basal body rod
E4T55_RS14175	COG4786	Flagellar basal body rod
E4T55_RS14180	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
E4T55_RS14185	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
E4T55_RS14195	COG1684	flagellar biosynthetic protein fliR
E4T55_RS14200	COG1987	bacterial-type flagellum assembly
E4T55_RS14275	COG0589	response to stress
E4T55_RS14280	COG0196	riboflavin kinase activity
E4T55_RS14295	COG0800	Aldolase
E4T55_RS14305	COG1166	arginine decarboxylase activity
E4T55_RS14325	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
E4T55_RS14330	COG1381	Involved in DNA repair and RecF pathway recombination
E4T55_RS14340	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
E4T55_RS14340	COG0674	pyruvate-flavodoxin oxidoreductase activity
E4T55_RS14345	COG1013	pyruvate-flavodoxin oxidoreductase activity
E4T55_RS14355	COG0670	Belongs to the BI1 family
E4T55_RS14410	COG0069	glutamate synthase activity
E4T55_RS14415	COG0204	Acyl-transferase
E4T55_RS14485	COG0505	Belongs to the CarA family
E4T55_RS14490	COG2814	Major facilitator Superfamily
E4T55_RS14500	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
E4T55_RS14505	COG3961	Belongs to the TPP enzyme family
E4T55_RS14535	COG1183	phosphatidylcholine synthase activity
E4T55_RS14540	COG1012	belongs to the aldehyde dehydrogenase family
E4T55_RS14545	COG1376	ErfK ybiS ycfS ynhG family protein
E4T55_RS14555	COG3038	cytochrome b561
E4T55_RS14570	COG3220	belongs to the UPF0276 family
E4T55_RS14580	COG5433	transposase activity
E4T55_RS14610	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
E4T55_RS14615	COG2255	four-way junction helicase activity
E4T55_RS14675	COG0531	amino acid
E4T55_RS14680	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
E4T55_RS14705	COG1278	Cold shock
E4T55_RS14710	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
E4T55_RS14715	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
E4T55_RS14735	COG0151	Belongs to the GarS family
E4T55_RS14740	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
E4T55_RS14750	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
E4T55_RS14775	COG0564	pseudouridine synthase activity
E4T55_RS14785	COG2271	Major facilitator Superfamily
E4T55_RS14800	COG0285	dihydrofolate synthase activity
E4T55_RS14810	COG1286	toxin biosynthetic process
E4T55_RS14825	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
E4T55_RS14830	COG0495	leucyl-tRNA aminoacylation
E4T55_RS14835	COG0815	Transfers the fatty acyl group on membrane lipoproteins
E4T55_RS14850	COG1012	belongs to the aldehyde dehydrogenase family
E4T55_RS14870	COG4974	Belongs to the 'phage' integrase family
E4T55_RS14890	COG1192	Involved in chromosome partitioning
E4T55_RS14905	COG3436	PFAM IS66 Orf2 family protein
E4T55_RS14910	COG2433	Pfam Transposase IS66
E4T55_RS14945	COG3041	Addiction module toxin RelE StbE family
E4T55_RS14950	COG3077	Addiction module antitoxin, RelB DinJ family
E4T55_RS15010	COG0494	nUDIX hydrolase
E4T55_RS15055	COG4974	Belongs to the 'phage' integrase family