locus-tag	class	description
GJD98_RS00010	COG0592	DNA-directed DNA polymerase activity
GJD98_RS00020	COG0187	DNA topoisomerase II activity
GJD98_RS00025	COG2957	Belongs to the agmatine deiminase family
GJD98_RS00030	COG1166	arginine decarboxylase activity
GJD98_RS00050	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GJD98_RS00055	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GJD98_RS00065	COG1741	Belongs to the pirin family
GJD98_RS00075	COG1566	PFAM secretion protein HlyD family protein
GJD98_RS00095	COG3227	Zinc metalloprotease (Elastase)
GJD98_RS00105	COG3028	Belongs to the UPF0307 family
GJD98_RS00130	COG0531	amino acid
GJD98_RS00135	COG0306	phosphate transporter
GJD98_RS00145	COG5001	Diguanylate cyclase
GJD98_RS00145	COG3300	MHYT domain
GJD98_RS00155	COG2234	aminopeptidase activity
GJD98_RS00215	COG3781	membrane
GJD98_RS00265	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GJD98_RS00280	COG0583	DNA-binding transcription factor activity
GJD98_RS00295	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GJD98_RS00365	COG0436	Aminotransferase
GJD98_RS00370	COG0556	nucleotide-excision repair
GJD98_RS00380	COG2203	Gaf domain
GJD98_RS00380	COG3706	GGDEF domain
GJD98_RS00380	COG4251	negative regulation of phosphorylation
GJD98_RS00380	COG5001	Diguanylate cyclase
GJD98_RS00385	COG0069	glutamate synthase activity
GJD98_RS00390	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
GJD98_RS00395	COG3079	Belongs to the UPF0149 family
GJD98_RS00400	COG0006	proline dipeptidase activity
GJD98_RS00405	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GJD98_RS00410	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GJD98_RS00440	COG4067	protein conserved in archaea
GJD98_RS00440	COG0189	ligase activity
GJD98_RS00460	COG1671	Belongs to the UPF0178 family
GJD98_RS00475	COG0557	exoribonuclease II activity
GJD98_RS00480	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GJD98_RS00485	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GJD98_RS00500	COG2824	Alkylphosphonate utilization operon protein PhnA
GJD98_RS00525	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GJD98_RS00535	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GJD98_RS00545	COG2252	PERMEase
GJD98_RS00580	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GJD98_RS00585	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GJD98_RS00595	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GJD98_RS00605	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GJD98_RS00625	COG1116	anion transmembrane transporter activity
GJD98_RS00630	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GJD98_RS00650	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GJD98_RS00665	COG3360	Dodecin
GJD98_RS00675	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GJD98_RS00700	COG0469	pyruvate kinase activity
GJD98_RS00705	COG0126	phosphoglycerate kinase activity
GJD98_RS00710	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GJD98_RS00715	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GJD98_RS00725	COG0339	signal peptide processing
GJD98_RS00810	COG5001	Diguanylate cyclase
GJD98_RS00815	COG2200	EAL domain
GJD98_RS00820	COG0024	Methionine aminopeptidase
GJD98_RS00860	COG2354	Protein conserved in bacteria
GJD98_RS00865	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GJD98_RS00895	COG0583	DNA-binding transcription factor activity
GJD98_RS00910	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GJD98_RS00915	COG2814	Major facilitator Superfamily
GJD98_RS00925	COG2226	methyltransferase
GJD98_RS00930	COG0501	Belongs to the peptidase M48B family
GJD98_RS00960	COG1172	Belongs to the binding-protein-dependent transport system permease family
GJD98_RS00970	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GJD98_RS01035	COG1271	oxidase subunit
GJD98_RS01040	COG1294	oxidase, subunit
GJD98_RS01055	COG1307	EDD domain protein, DegV family
GJD98_RS01060	COG1028	Short-chain dehydrogenase reductase Sdr
GJD98_RS01065	COG3046	protein related to deoxyribodipyrimidine photolyase
GJD98_RS01100	COG0415	Belongs to the DNA photolyase family
GJD98_RS01105	COG1346	cytolysis
GJD98_RS01110	COG1380	Effector of murein hydrolase LrgA
GJD98_RS01115	COG0583	DNA-binding transcription factor activity
GJD98_RS01120	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
GJD98_RS01145	COG3002	Belongs to the UPF0753 family
GJD98_RS01150	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GJD98_RS01155	COG0583	DNA-binding transcription factor activity
GJD98_RS01180	COG0531	amino acid
GJD98_RS01190	COG3706	GGDEF domain
GJD98_RS01195	COG2217	Heavy metal translocating P-type atpase
GJD98_RS01200	COG0735	belongs to the Fur family
GJD98_RS01210	COG1196	nuclear chromosome segregation
GJD98_RS01230	COG1012	belongs to the aldehyde dehydrogenase family
GJD98_RS01245	COG2066	Belongs to the glutaminase family
GJD98_RS01250	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GJD98_RS01280	COG1393	Belongs to the ArsC family
GJD98_RS01290	COG0513	Belongs to the DEAD box helicase family
GJD98_RS01300	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GJD98_RS01325	COG1566	PFAM secretion protein HlyD family protein
GJD98_RS01355	COG1573	uracil-dna glycosylase
GJD98_RS01380	COG0598	Magnesium transport protein CorA
GJD98_RS01390	COG0433	COG0433 Predicted ATPase
GJD98_RS01395	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GJD98_RS01400	COG1335	isochorismatase
GJD98_RS01410	COG2814	Major facilitator Superfamily
GJD98_RS01415	COG0583	DNA-binding transcription factor activity
GJD98_RS01435	COG5002	protein histidine kinase activity
GJD98_RS01435	COG2198	Histidine kinase
GJD98_RS01435	COG0784	Response regulator, receiver
GJD98_RS01445	COG0583	DNA-binding transcription factor activity
GJD98_RS01455	COG2226	methyltransferase
GJD98_RS01475	COG4221	oxidoreductase activity
GJD98_RS01485	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GJD98_RS01490	COG1509	lysine 2,3-aminomutase activity
GJD98_RS01525	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GJD98_RS01535	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GJD98_RS01540	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GJD98_RS01610	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GJD98_RS01640	COG0085	RNA polymerase activity
GJD98_RS01645	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GJD98_RS01660	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GJD98_RS01810	COG0629	single-stranded DNA binding
GJD98_RS01815	COG2814	Major facilitator Superfamily
GJD98_RS01820	COG1028	Short-chain dehydrogenase reductase Sdr
GJD98_RS01835	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GJD98_RS01845	COG1560	Kdo2-lipid A biosynthetic process
GJD98_RS01860	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GJD98_RS01885	COG2867	negative regulation of translational initiation
GJD98_RS01890	COG2914	Belongs to the UPF0125 (RnfH) family
GJD98_RS01895	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GJD98_RS01900	COG0735	belongs to the Fur family
GJD98_RS01905	COG3706	GGDEF domain
GJD98_RS01930	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
GJD98_RS01965	COG1704	LemA family
GJD98_RS01975	COG0842	Transport permease protein
GJD98_RS01980	COG1131	(ABC) transporter
GJD98_RS02015	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GJD98_RS02025	COG0336	Belongs to the RNA methyltransferase TrmD family
GJD98_RS02030	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GJD98_RS02040	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GJD98_RS02060	COG0531	amino acid
GJD98_RS02100	COG1612	heme a metabolic process
GJD98_RS02110	COG1999	signal sequence binding
GJD98_RS02125	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GJD98_RS02130	COG0363	glucosamine-6-phosphate deaminase activity
GJD98_RS02135	COG0129	dihydroxy-acid dehydratase activity
GJD98_RS02140	COG0837	glucose binding
GJD98_RS02145	COG0800	Aldolase
GJD98_RS02150	COG2814	Major facilitator Superfamily
GJD98_RS02160	COG3655	Transcriptional regulator
GJD98_RS02170	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GJD98_RS02175	COG1278	Cold shock
GJD98_RS02195	COG1566	PFAM secretion protein HlyD family protein
GJD98_RS02210	COG1733	regulation of RNA biosynthetic process
GJD98_RS02330	COG0477	Major facilitator Superfamily
GJD98_RS02345	COG0138	bifunctional purine biosynthesis protein purh
GJD98_RS02350	COG2264	protein methyltransferase activity
GJD98_RS02355	COG0439	Biotin carboxylase
GJD98_RS02360	COG0511	ligase activity, forming carbon-carbon bonds
GJD98_RS02375	COG5016	pyruvate
GJD98_RS02375	COG0511	ligase activity, forming carbon-carbon bonds
GJD98_RS02380	COG3227	Zinc metalloprotease (Elastase)
GJD98_RS02390	COG3568	Endonuclease Exonuclease Phosphatase
GJD98_RS02395	COG3588	fructose-bisphosphate aldolase
GJD98_RS02415	COG1183	phosphatidylcholine synthase activity
GJD98_RS02425	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GJD98_RS02430	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GJD98_RS02450	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GJD98_RS02455	COG1363	Peptidase, m42
GJD98_RS02465	COG0330	HflC and HflK could
GJD98_RS02470	COG0330	HflC and HflK could
GJD98_RS02475	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GJD98_RS02495	COG1438	arginine binding
GJD98_RS02500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GJD98_RS02505	COG0765	amino acid transport
GJD98_RS02510	COG1126	abc transporter atp-binding protein
GJD98_RS02515	COG0137	argininosuccinate synthase activity
GJD98_RS02520	COG0165	Argininosuccinate lyase
GJD98_RS02525	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GJD98_RS02540	COG0793	Belongs to the peptidase S41A family
GJD98_RS02545	COG4942	peptidase
GJD98_RS02550	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GJD98_RS02565	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GJD98_RS02570	COG0575	Belongs to the CDS family
GJD98_RS02590	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GJD98_RS02595	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GJD98_RS02600	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GJD98_RS02605	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GJD98_RS02610	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GJD98_RS02635	COG0656	L-ascorbic acid biosynthetic process
GJD98_RS02660	COG0572	uridine kinase
GJD98_RS02695	COG2009	succinate dehydrogenase
GJD98_RS02700	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
GJD98_RS02705	COG1053	succinate dehydrogenase
GJD98_RS02710	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GJD98_RS02720	COG0508	dehydrogenase complex catalyzes the overall conversion of
GJD98_RS02730	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GJD98_RS02750	COG2814	Major facilitator Superfamily
GJD98_RS02760	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
GJD98_RS02765	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GJD98_RS02785	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
GJD98_RS02835	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GJD98_RS02855	COG1028	Short-chain dehydrogenase reductase Sdr
GJD98_RS02860	COG1028	Short-chain dehydrogenase reductase Sdr
GJD98_RS02880	COG2715	membrane protein required for spore maturation
GJD98_RS02885	COG0700	Nucleoside recognition
GJD98_RS02890	COG0739	heme binding
GJD98_RS02895	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GJD98_RS02920	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GJD98_RS02925	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GJD98_RS02930	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GJD98_RS02945	COG0306	phosphate transporter
GJD98_RS02950	COG1392	Phosphate transport regulator
GJD98_RS02965	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GJD98_RS02970	COG0540	Belongs to the ATCase OTCase family
GJD98_RS02980	COG0606	chelatase, subunit chli
GJD98_RS02990	COG0347	Belongs to the P(II) protein family
GJD98_RS02995	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GJD98_RS03030	COG3243	poly(R)-hydroxyalkanoic acid synthase
GJD98_RS03035	COG1959	2 iron, 2 sulfur cluster binding
GJD98_RS03040	COG0719	Fe-S assembly protein
GJD98_RS03045	COG0396	ATPase activity
GJD98_RS03050	COG0719	Fe-S assembly protein
GJD98_RS03055	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GJD98_RS03060	COG0822	iron-sulfur transferase activity
GJD98_RS03065	COG2151	metal-sulfur cluster biosynthetic enzyme
GJD98_RS03070	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
GJD98_RS03075	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
GJD98_RS03080	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GJD98_RS03090	COG1253	flavin adenine dinucleotide binding
GJD98_RS03095	COG1064	alcohol dehydrogenase
GJD98_RS03140	COG0519	Catalyzes the synthesis of GMP from XMP
GJD98_RS03275	COG2852	Protein conserved in bacteria
GJD98_RS03280	COG0708	Exodeoxyribonuclease III
GJD98_RS03285	COG0708	Exodeoxyribonuclease III
GJD98_RS03295	COG0281	malic enzyme
GJD98_RS03310	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GJD98_RS03315	COG0814	amino acid
GJD98_RS03320	COG0814	amino acid
GJD98_RS03335	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GJD98_RS03340	COG1131	(ABC) transporter
GJD98_RS03345	COG0842	Transport permease protein
GJD98_RS03350	COG0842	Transport permease protein
GJD98_RS03360	COG0741	lytic transglycosylase activity
GJD98_RS03365	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GJD98_RS03380	COG3220	belongs to the UPF0276 family
GJD98_RS03400	COG4689	acetoacetate decarboxylase
GJD98_RS03420	COG3220	belongs to the UPF0276 family
GJD98_RS03450	COG1131	(ABC) transporter
GJD98_RS03465	COG4232	protein-disulfide reductase activity
GJD98_RS03480	COG0783	Belongs to the Dps family
GJD98_RS03485	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GJD98_RS03495	COG0187	DNA topoisomerase II activity
GJD98_RS03515	COG0666	response to abiotic stimulus
GJD98_RS03515	COG3177	Filamentation induced by cAMP protein fic
GJD98_RS03520	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
GJD98_RS03525	COG0659	secondary active sulfate transmembrane transporter activity
GJD98_RS03535	COG1538	Outer membrane efflux protein
GJD98_RS03540	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GJD98_RS03545	COG0156	8-amino-7-oxononanoate synthase activity
GJD98_RS03555	COG0488	(ABC) transporter
GJD98_RS03585	COG0010	Belongs to the arginase family
GJD98_RS03605	COG1297	OPT oligopeptide transporter protein
GJD98_RS03610	COG5002	protein histidine kinase activity
GJD98_RS03615	COG0745	RESPONSE REGULATOR receiver
GJD98_RS03630	COG1823	symporter activity
GJD98_RS03640	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GJD98_RS03645	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GJD98_RS03680	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GJD98_RS03685	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GJD98_RS03690	COG0628	permease
GJD98_RS03715	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GJD98_RS03725	COG0305	Participates in initiation and elongation during chromosome replication
GJD98_RS03765	COG2827	Endonuclease containing a URI domain
GJD98_RS03785	COG0107	imidazoleglycerol-phosphate synthase activity
GJD98_RS03795	COG1083	cytidylyl-transferase
GJD98_RS03800	COG2089	acid synthase
GJD98_RS03805	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GJD98_RS03815	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GJD98_RS03830	COG1088	dTDP-glucose 4,6-dehydratase activity
GJD98_RS03850	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GJD98_RS03890	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GJD98_RS03955	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
GJD98_RS03955	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
GJD98_RS03960	COG2091	lysine biosynthetic process via aminoadipic acid
GJD98_RS03970	COG0037	tRNA processing
GJD98_RS03985	COG1696	Membrane protein involved in D-alanine export
GJD98_RS03990	COG1760	l-serine dehydratase
GJD98_RS03995	COG0545	Peptidyl-prolyl cis-trans isomerase
GJD98_RS04000	COG2223	nitrite transmembrane transporter activity
GJD98_RS04025	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GJD98_RS04030	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GJD98_RS04035	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GJD98_RS04040	COG0659	secondary active sulfate transmembrane transporter activity
GJD98_RS04045	COG1960	acyl-CoA dehydrogenase activity
GJD98_RS04055	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GJD98_RS04055	COG0574	Belongs to the PEP-utilizing enzyme family
GJD98_RS04060	COG0475	glutathione-regulated potassium exporter activity
GJD98_RS04075	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GJD98_RS04080	COG1555	photosystem II stabilization
GJD98_RS04085	COG1077	Cell shape determining protein MreB Mrl
GJD98_RS04090	COG1792	Involved in formation and maintenance of cell shape
GJD98_RS04095	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GJD98_RS04100	COG1187	pseudouridine synthase activity
GJD98_RS04120	COG0542	response to heat
GJD98_RS04150	COG0705	Rhomboid family
GJD98_RS04155	COG0739	heme binding
GJD98_RS04215	COG0512	Glutamine amidotransferase of anthranilate synthase
GJD98_RS04220	COG1137	ATPase activity
GJD98_RS04235	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
GJD98_RS04245	COG1127	ABC transporter
GJD98_RS04250	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GJD98_RS04255	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GJD98_RS04270	COG5007	Belongs to the BolA IbaG family
GJD98_RS04285	COG1136	(ABC) transporter
GJD98_RS04290	COG0577	efflux transmembrane transporter activity
GJD98_RS04295	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GJD98_RS04315	COG0616	signal peptide processing
GJD98_RS04345	COG1138	Cytochrome C-type biogenesis protein
GJD98_RS04365	COG3360	Dodecin
GJD98_RS04380	COG0514	ATP-dependent DNA helicase (RecQ)
GJD98_RS04385	COG1960	acyl-CoA dehydrogenase activity
GJD98_RS04390	COG1024	Enoyl-CoA hydratase
GJD98_RS04395	COG1024	Enoyl-CoA hydratase
GJD98_RS04430	COG2340	Cysteine-rich secretory protein family
GJD98_RS04440	COG3706	GGDEF domain
GJD98_RS04465	COG1472	Belongs to the glycosyl hydrolase 3 family
GJD98_RS04485	COG0204	Acyl-transferase
GJD98_RS04490	COG0626	cystathionine gamma-synthase activity
GJD98_RS04535	COG1194	a g-specific adenine glycosylase
GJD98_RS04565	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GJD98_RS04590	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
GJD98_RS04645	COG1994	Peptidase M50
GJD98_RS04670	COG0686	Belongs to the AlaDH PNT family
GJD98_RS04715	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GJD98_RS04725	COG0589	response to stress
GJD98_RS04730	COG0196	riboflavin kinase activity
GJD98_RS04735	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GJD98_RS04745	COG0800	Aldolase
GJD98_RS04760	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GJD98_RS04765	COG1381	Involved in DNA repair and RecF pathway recombination
GJD98_RS04785	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GJD98_RS04785	COG0674	pyruvate-flavodoxin oxidoreductase activity
GJD98_RS04790	COG1013	pyruvate-flavodoxin oxidoreductase activity
GJD98_RS04795	COG0670	Belongs to the BI1 family
GJD98_RS04805	COG0312	modulator of DNA gyrase
GJD98_RS04810	COG1752	Esterase of the alpha-beta hydrolase superfamily
GJD98_RS04815	COG1022	Amp-dependent synthetase and ligase
GJD98_RS04820	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GJD98_RS04850	COG0601	transmembrane transport
GJD98_RS04855	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GJD98_RS04870	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
GJD98_RS04900	COG0833	amino acid
GJD98_RS04935	COG2135	peptidase activity
GJD98_RS04965	COG0629	single-stranded DNA binding
GJD98_RS05120	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GJD98_RS05160	COG2217	Heavy metal translocating P-type atpase
GJD98_RS05185	COG0300	oxidoreductase activity
GJD98_RS05220	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GJD98_RS05225	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
GJD98_RS05230	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
GJD98_RS05235	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GJD98_RS05240	COG2217	Heavy metal translocating P-type atpase
GJD98_RS05245	COG5002	protein histidine kinase activity
GJD98_RS05245	COG5001	Diguanylate cyclase
GJD98_RS05245	COG3447	MASE1 domain protein
GJD98_RS05295	COG2132	Multicopper oxidase
GJD98_RS05340	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GJD98_RS05365	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GJD98_RS05365	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GJD98_RS05375	COG0356	it plays a direct role in the translocation of protons across the membrane
GJD98_RS05390	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GJD98_RS05420	COG1028	Short-chain dehydrogenase reductase Sdr
GJD98_RS05425	COG1278	Cold shock
GJD98_RS05475	COG0582	viral genome integration into host DNA
GJD98_RS05515	COG0232	Belongs to the dGTPase family. Type 2 subfamily
GJD98_RS05535	COG4804	nuclease activity
GJD98_RS05540	COG0582	viral genome integration into host DNA
GJD98_RS05550	COG0728	peptidoglycan biosynthetic process
GJD98_RS05580	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GJD98_RS05585	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GJD98_RS05600	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GJD98_RS05605	COG2217	Heavy metal translocating P-type atpase
GJD98_RS05650	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GJD98_RS05650	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GJD98_RS05705	COG4251	negative regulation of phosphorylation
GJD98_RS05710	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
GJD98_RS05715	COG3325	Belongs to the glycosyl hydrolase 18 family
GJD98_RS05715	COG3469	chitinase activity
GJD98_RS05745	COG0741	lytic transglycosylase activity
GJD98_RS05745	COG1388	LysM domain
GJD98_RS05760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GJD98_RS05775	COG0590	tRNA wobble adenosine to inosine editing
GJD98_RS05795	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GJD98_RS05810	COG2070	2-Nitropropane dioxygenase
GJD98_RS05840	COG1177	transmembrane transport
GJD98_RS05845	COG1176	ABC-type spermidine putrescine transport system, permease component I
GJD98_RS05850	COG3842	ATPase activity
GJD98_RS05875	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GJD98_RS05910	COG1231	oxidoreductase activity
GJD98_RS05920	COG3961	Belongs to the TPP enzyme family
GJD98_RS05940	COG0697	spore germination
GJD98_RS05965	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GJD98_RS05980	COG1666	GTP binding
GJD98_RS05990	COG1355	regulation of microtubule-based process
GJD98_RS06030	COG4783	chaperone-mediated protein folding
GJD98_RS06035	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GJD98_RS06035	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GJD98_RS06040	COG0307	riboflavin synthase, alpha
GJD98_RS06045	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GJD98_RS06045	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GJD98_RS06070	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GJD98_RS06085	COG2974	May be involved in recombination
GJD98_RS06100	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GJD98_RS06105	COG1472	Belongs to the glycosyl hydrolase 3 family
GJD98_RS06115	COG0140	phosphoribosyl-ATP diphosphatase activity
GJD98_RS06115	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GJD98_RS06120	COG0107	imidazoleglycerol-phosphate synthase activity
GJD98_RS06125	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GJD98_RS06130	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GJD98_RS06135	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GJD98_RS06135	COG0131	Imidazoleglycerol-phosphate dehydratase
GJD98_RS06140	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GJD98_RS06150	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GJD98_RS06160	COG1271	oxidase subunit
GJD98_RS06165	COG1294	oxidase, subunit
GJD98_RS06180	COG1278	Cold shock
GJD98_RS06190	COG0442	prolyl-tRNA aminoacylation
GJD98_RS06195	COG1846	Transcriptional regulator
GJD98_RS06210	COG1280	lysine exporter protein (LysE YggA)
GJD98_RS06235	COG1815	bacterial-type flagellum-dependent cell motility
GJD98_RS06245	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GJD98_RS06250	COG1749	Flagellar hook protein flgE
GJD98_RS06255	COG4787	bacterial-type flagellum-dependent cell motility
GJD98_RS06260	COG4786	Flagellar basal body rod
GJD98_RS06270	COG1706	bacterial-type flagellum-dependent cell motility
GJD98_RS06320	COG1132	(ABC) transporter
GJD98_RS06335	COG0281	malic enzyme
GJD98_RS06345	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
GJD98_RS06360	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
GJD98_RS06365	COG0217	transcriptional regulatory protein
GJD98_RS06370	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GJD98_RS06375	COG0632	four-way junction helicase activity
GJD98_RS06390	COG0642	Histidine kinase
GJD98_RS06400	COG2917	probably involved in intracellular septation
GJD98_RS06405	COG0741	lytic transglycosylase activity
GJD98_RS06405	COG1388	LysM domain
GJD98_RS06410	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GJD98_RS06415	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
GJD98_RS06425	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GJD98_RS06445	COG1090	epimerase
GJD98_RS06455	COG0135	phosphoribosylanthranilate isomerase activity
GJD98_RS06460	COG0133	tryptophan synthase activity
GJD98_RS06465	COG0159	tryptophan synthase activity
GJD98_RS06470	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GJD98_RS06475	COG0215	cysteine-tRNA ligase activity
GJD98_RS06480	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GJD98_RS06545	COG0673	inositol 2-dehydrogenase activity
GJD98_RS06550	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
GJD98_RS06555	COG2814	Major facilitator Superfamily
GJD98_RS06560	COG2814	Major facilitator Superfamily
GJD98_RS06565	COG4264	IucA IucC family
GJD98_RS06600	COG1496	oxidoreductase activity
GJD98_RS06650	COG0285	dihydrofolate synthase activity
GJD98_RS06660	COG1286	toxin biosynthetic process
GJD98_RS06665	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GJD98_RS06680	COG0495	leucyl-tRNA aminoacylation
GJD98_RS06685	COG0815	Transfers the fatty acyl group on membrane lipoproteins
GJD98_RS06695	COG1012	belongs to the aldehyde dehydrogenase family
GJD98_RS06700	COG1250	3-hydroxyacyl-CoA dehydrogenase
GJD98_RS06700	COG1024	Enoyl-CoA hydratase
GJD98_RS06705	COG0183	Belongs to the thiolase family
GJD98_RS06730	COG3156	type II secretion system protein K
GJD98_RS06750	COG2165	general secretion pathway protein
GJD98_RS06760	COG0174	glutamine synthetase
GJD98_RS06770	COG3022	response to hydroperoxide
GJD98_RS06775	COG2515	1-aminocyclopropane-1-carboxylate deaminase
GJD98_RS06785	COG0326	Molecular chaperone. Has ATPase activity
GJD98_RS06790	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
GJD98_RS06795	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GJD98_RS06800	COG0673	inositol 2-dehydrogenase activity
GJD98_RS06805	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GJD98_RS06810	COG0772	Belongs to the SEDS family
GJD98_RS06815	COG0768	penicillin binding
GJD98_RS06820	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GJD98_RS06835	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GJD98_RS06840	COG2986	histidine ammonia-lyase
GJD98_RS06850	COG0300	oxidoreductase activity
GJD98_RS06880	COG0316	Belongs to the HesB IscA family
GJD98_RS06885	COG0482	sulfurtransferase activity
GJD98_RS06905	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GJD98_RS06910	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GJD98_RS06920	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GJD98_RS06925	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GJD98_RS06930	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GJD98_RS06935	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GJD98_RS06940	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GJD98_RS06950	COG0084	hydrolase, TatD family'
GJD98_RS06955	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
GJD98_RS06970	COG0463	Glycosyl transferase, family 2
GJD98_RS07000	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GJD98_RS07010	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GJD98_RS07015	COG0372	Belongs to the citrate synthase family
GJD98_RS07030	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GJD98_RS07035	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GJD98_RS07040	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GJD98_RS07055	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
GJD98_RS07065	COG0284	orotidine-5'-phosphate decarboxylase activity
GJD98_RS07075	COG4221	oxidoreductase activity
GJD98_RS07090	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
GJD98_RS07110	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GJD98_RS07115	COG0295	cytidine deaminase activity
GJD98_RS07130	COG0745	RESPONSE REGULATOR receiver
GJD98_RS07135	COG4535	Mg2 and Co2 transporter CorC
GJD98_RS07145	COG1702	phosphate starvation-inducible protein PhoH
GJD98_RS07150	COG0613	PHP domain protein
GJD98_RS07155	COG0009	L-threonylcarbamoyladenylate synthase
GJD98_RS07160	COG0180	Tryptophanyl-tRNA synthetase
GJD98_RS07170	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GJD98_RS07175	COG1187	pseudouridine synthase activity
GJD98_RS07195	COG1881	PFAM PEBP family protein
GJD98_RS07220	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GJD98_RS07225	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GJD98_RS07235	COG0436	Aminotransferase
GJD98_RS07245	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GJD98_RS07250	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GJD98_RS07255	COG0653	protein targeting
GJD98_RS07260	COG0494	nUDIX hydrolase
GJD98_RS07275	COG0237	dephospho-CoA kinase activity
GJD98_RS07285	COG2200	EAL domain
GJD98_RS07295	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GJD98_RS07305	COG0156	8-amino-7-oxononanoate synthase activity
GJD98_RS07310	COG0596	Alpha beta hydrolase
GJD98_RS07315	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GJD98_RS07330	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GJD98_RS07335	COG3264	Mechanosensitive ion channel
GJD98_RS07335	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
GJD98_RS07370	COG1522	sequence-specific DNA binding
GJD98_RS07415	COG1196	nuclear chromosome segregation
GJD98_RS07420	COG0308	aminopeptidase N
GJD98_RS07440	COG0456	acetyltransferase
GJD98_RS07445	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GJD98_RS07450	COG0508	dehydrogenase complex catalyzes the overall conversion of
GJD98_RS07465	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
GJD98_RS07470	COG0475	glutathione-regulated potassium exporter activity
GJD98_RS07470	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GJD98_RS07475	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GJD98_RS07480	COG1686	Belongs to the peptidase S11 family
GJD98_RS07490	COG2921	Belongs to the UPF0250 family
GJD98_RS07495	COG0321	lipoyl(octanoyl) transferase activity
GJD98_RS07500	COG0586	Pfam SNARE associated Golgi protein
GJD98_RS07510	COG3034	peptidoglycan biosynthetic process
GJD98_RS07515	COG2274	protein secretion by the type I secretion system
GJD98_RS07530	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
GJD98_RS07555	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
GJD98_RS07585	COG0372	Belongs to the citrate synthase family
GJD98_RS07595	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
GJD98_RS07595	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GJD98_RS07605	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GJD98_RS07615	COG1981	membrane
GJD98_RS07620	COG0861	Integral membrane protein TerC family
GJD98_RS07625	COG0617	tRNA 3'-terminal CCA addition
GJD98_RS07630	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GJD98_RS07635	COG0589	response to stress
GJD98_RS07640	COG1160	GTP binding
GJD98_RS07655	COG0124	histidyl-tRNA synthetase
GJD98_RS07665	COG3063	Type IV pilus biogenesis stability protein PilW
GJD98_RS07670	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GJD98_RS07675	COG0105	UTP biosynthetic process
GJD98_RS07695	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GJD98_RS07700	COG0850	regulation of cytokinetic process
GJD98_RS07705	COG0318	PFAM AMP-dependent synthetase and ligase
GJD98_RS07710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GJD98_RS07720	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GJD98_RS07740	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
GJD98_RS07740	COG3264	Mechanosensitive ion channel
GJD98_RS07745	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GJD98_RS07760	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GJD98_RS07780	COG0352	thiamine-phosphate diphosphorylase activity
GJD98_RS07795	COG0823	Involved in the tonB-independent uptake of proteins
GJD98_RS07815	COG0824	Thioesterase
GJD98_RS07820	COG2255	four-way junction helicase activity
GJD98_RS07845	COG3038	cytochrome b561
GJD98_RS07850	COG2902	Dehydrogenase
GJD98_RS07855	COG1376	ErfK ybiS ycfS ynhG family protein
GJD98_RS07860	COG1012	belongs to the aldehyde dehydrogenase family
GJD98_RS07865	COG1183	phosphatidylcholine synthase activity
GJD98_RS07920	COG1376	ErfK ybiS ycfS ynhG family protein
GJD98_RS07920	COG1388	LysM domain
GJD98_RS07925	COG1250	3-hydroxyacyl-CoA dehydrogenase
GJD98_RS07925	COG1024	Enoyl-CoA hydratase
GJD98_RS07930	COG0183	Belongs to the thiolase family
GJD98_RS07960	COG5654	RES domain protein
GJD98_RS07970	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GJD98_RS07975	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GJD98_RS07980	COG0494	nUDIX hydrolase
GJD98_RS07985	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GJD98_RS07990	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GJD98_RS07995	COG0789	Transcriptional regulator
GJD98_RS08010	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GJD98_RS08010	COG0456	acetyltransferase
GJD98_RS08015	COG1132	(ABC) transporter
GJD98_RS08020	COG0488	(ABC) transporter
GJD98_RS08035	COG0768	penicillin binding
GJD98_RS08055	COG0585	pseudouridine synthase activity
GJD98_RS08060	COG0429	hydrolase of the alpha beta-hydrolase fold
GJD98_RS08070	COG2217	Heavy metal translocating P-type atpase
GJD98_RS08095	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GJD98_RS08100	COG0438	transferase activity, transferring glycosyl groups
GJD98_RS08110	COG0247	lactate metabolic process
GJD98_RS08110	COG0277	FAD linked oxidase domain protein
GJD98_RS08130	COG0477	Major facilitator Superfamily
GJD98_RS08140	COG2119	membrane
GJD98_RS08145	COG0823	Involved in the tonB-independent uptake of proteins
GJD98_RS08155	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GJD98_RS08170	COG3038	cytochrome b561
GJD98_RS08175	COG2353	YceI-like domain
GJD98_RS08195	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GJD98_RS08200	COG0673	inositol 2-dehydrogenase activity
GJD98_RS08205	COG2814	Major facilitator Superfamily
GJD98_RS08230	COG0531	amino acid
GJD98_RS08260	COG4953	penicillin-binding protein 1C
GJD98_RS08265	COG2373	Large extracellular alpha-helical protein
GJD98_RS08305	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GJD98_RS08310	COG0151	Belongs to the GarS family
GJD98_RS08330	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GJD98_RS08335	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GJD98_RS08350	COG4232	protein-disulfide reductase activity
GJD98_RS08360	COG0300	oxidoreductase activity
GJD98_RS08390	COG3144	bacterial-type flagellum assembly
GJD98_RS08400	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GJD98_RS08405	COG0531	amino acid
GJD98_RS08460	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GJD98_RS08465	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GJD98_RS08475	COG3138	arginine N-succinyltransferase
GJD98_RS08480	COG1012	belongs to the aldehyde dehydrogenase family
GJD98_RS08505	COG0528	UMP kinase activity
GJD98_RS08515	COG0052	Belongs to the universal ribosomal protein uS2 family
GJD98_RS08545	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
GJD98_RS08555	COG0519	Catalyzes the synthesis of GMP from XMP
GJD98_RS08555	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GJD98_RS08565	COG2894	cell division
GJD98_RS08575	COG1960	acyl-CoA dehydrogenase activity
GJD98_RS08580	COG2267	carboxylic ester hydrolase activity
GJD98_RS08595	COG0395	ABC-type sugar transport system, permease component
GJD98_RS08600	COG1175	transmembrane transport
GJD98_RS08605	COG1063	alcohol dehydrogenase
GJD98_RS08610	COG0038	chloride channel
GJD98_RS08615	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GJD98_RS08615	COG0512	Glutamine amidotransferase of anthranilate synthase
GJD98_RS08620	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GJD98_RS08625	COG0154	amidase activity
GJD98_RS08630	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GJD98_RS08665	COG0316	Belongs to the HesB IscA family
GJD98_RS08675	COG1104	cysteine desulfurase activity
GJD98_RS08680	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
GJD98_RS08690	COG0616	signal peptide processing
GJD98_RS08695	COG0542	response to heat
GJD98_RS08710	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GJD98_RS08740	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GJD98_RS08750	COG1677	Flagellar hook-basal body complex protein FliE
GJD98_RS08765	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GJD98_RS08775	COG1674	ftsk spoiiie
GJD98_RS08780	COG0492	ferredoxin-NADP+ reductase activity
GJD98_RS08790	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GJD98_RS08790	COG0425	Belongs to the sulfur carrier protein TusA family
GJD98_RS08800	COG0312	modulator of DNA gyrase
GJD98_RS08815	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GJD98_RS08815	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GJD98_RS08850	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GJD98_RS08925	COG0583	DNA-binding transcription factor activity
GJD98_RS09000	COG2911	Protein conserved in bacteria
GJD98_RS09005	COG0113	porphobilinogen synthase activity
GJD98_RS09020	COG0527	aspartate kinase activity
GJD98_RS09030	COG0489	protein tyrosine kinase activity
GJD98_RS09040	COG0583	DNA-binding transcription factor activity
GJD98_RS09045	COG2814	Major facilitator Superfamily
GJD98_RS09060	COG1132	(ABC) transporter
GJD98_RS09085	COG1960	acyl-CoA dehydrogenase activity
GJD98_RS09090	COG0183	Belongs to the thiolase family
GJD98_RS09100	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GJD98_RS09105	COG1024	Enoyl-CoA hydratase
GJD98_RS09120	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GJD98_RS09130	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GJD98_RS09135	COG2011	ABC-type metal ion transport system permease component
GJD98_RS09140	COG1464	Belongs to the NlpA lipoprotein family
GJD98_RS09150	COG0742	ribosomal rna small subunit methyltransferase
GJD98_RS09155	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GJD98_RS09160	COG0751	glycine-tRNA ligase activity
GJD98_RS09175	COG0210	DNA helicase
GJD98_RS09195	COG0189	ligase activity
GJD98_RS09215	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GJD98_RS09225	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
GJD98_RS09230	COG0572	uridine kinase
GJD98_RS09260	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GJD98_RS09265	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GJD98_RS09305	COG0488	(ABC) transporter
GJD98_RS09310	COG0571	ribonuclease III activity
GJD98_RS09330	COG2951	lytic endotransglycosylase activity
GJD98_RS09340	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
GJD98_RS09375	COG0346	lactoylglutathione lyase activity
GJD98_RS09395	COG1254	Belongs to the acylphosphatase family
GJD98_RS09410	COG0657	acetylesterase activity
GJD98_RS09430	COG2223	nitrite transmembrane transporter activity
GJD98_RS09435	COG0038	chloride channel
GJD98_RS09445	COG3012	SEC-C Motif Domain Protein
GJD98_RS09455	COG0714	Associated with various cellular activities
GJD98_RS09470	COG2850	peptidyl-arginine hydroxylation
GJD98_RS09495	COG3101	peptidyl-lysine hydroxylation
GJD98_RS09505	COG0625	glutathione transferase activity
GJD98_RS09520	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GJD98_RS09530	COG0205	6-phosphofructokinase activity
GJD98_RS09535	COG4969	Belongs to the N-Me-Phe pilin family
GJD98_RS09540	COG4969	Belongs to the N-Me-Phe pilin family
GJD98_RS09550	COG0531	amino acid
GJD98_RS09555	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
GJD98_RS09560	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
GJD98_RS09570	COG1214	PFAM Peptidase M22, glycoprotease
GJD98_RS09575	COG1199	ATP-dependent helicase activity
GJD98_RS09580	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
GJD98_RS09605	COG2313	pseudouridylate synthase activity
GJD98_RS09635	COG3550	peptidyl-serine autophosphorylation
GJD98_RS09675	COG1250	3-hydroxyacyl-CoA dehydrogenase
GJD98_RS09690	COG5212	phosphodiesterase
GJD98_RS09725	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GJD98_RS09745	COG4948	Mandelate Racemase Muconate Lactonizing
GJD98_RS09825	COG0625	glutathione transferase activity
GJD98_RS09830	COG1764	response to oxidative stress
GJD98_RS09865	COG3774	pathogenesis
GJD98_RS09915	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GJD98_RS09945	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
GJD98_RS09965	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GJD98_RS09975	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GJD98_RS09980	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GJD98_RS09985	COG1862	Preprotein translocase
GJD98_RS09990	COG0343	queuine tRNA-ribosyltransferase activity
GJD98_RS09995	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GJD98_RS10005	COG0488	(ABC) transporter
GJD98_RS10010	COG3577	Aspartyl protease
GJD98_RS10020	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GJD98_RS10030	COG0194	GDP metabolic process
GJD98_RS10035	COG1561	YicC-like family, N-terminal region
GJD98_RS10085	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
GJD98_RS10090	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GJD98_RS10095	COG0505	Belongs to the CarA family
GJD98_RS10105	COG0443	Heat shock 70 kDa protein
GJD98_RS10115	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
GJD98_RS10120	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GJD98_RS10125	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GJD98_RS10135	COG0018	arginyl-trna synthetase
GJD98_RS10140	COG0628	permease
GJD98_RS10160	COG0424	maF-like protein
GJD98_RS10165	COG0148	phosphopyruvate hydratase activity
GJD98_RS10170	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
GJD98_RS10190	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
GJD98_RS10195	COG2885	chlorophyll binding
GJD98_RS10200	COG3218	ABC-type transport auxiliary lipoprotein component
GJD98_RS10210	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GJD98_RS10215	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GJD98_RS10235	COG1304	FMN binding
GJD98_RS10270	COG0582	viral genome integration into host DNA
GJD98_RS10305	COG1028	Short-chain dehydrogenase reductase Sdr
GJD98_RS10335	COG2217	Heavy metal translocating P-type atpase
GJD98_RS10370	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GJD98_RS10405	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GJD98_RS10425	COG2217	Heavy metal translocating P-type atpase
GJD98_RS10430	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GJD98_RS10440	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
GJD98_RS10460	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GJD98_RS10485	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GJD98_RS10490	COG4962	Type ii secretion system protein e
GJD98_RS10505	COG3451	type IV secretory pathway VirB4
GJD98_RS10525	COG2948	multi-organism process
GJD98_RS10540	COG3846	protein secretion by the type IV secretion system
GJD98_RS10550	COG4959	Type IV secretory pathway protease TraF
GJD98_RS10605	COG0582	viral genome integration into host DNA
GJD98_RS10645	COG5265	(ABC) transporter
GJD98_RS10650	COG5265	(ABC) transporter
GJD98_RS10655	COG0656	L-ascorbic acid biosynthetic process
GJD98_RS10680	COG3344	reverse transcriptase
GJD98_RS10810	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GJD98_RS10835	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GJD98_RS10835	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GJD98_RS10840	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GJD98_RS10840	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GJD98_RS10850	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GJD98_RS10880	COG3220	belongs to the UPF0276 family
GJD98_RS10905	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GJD98_RS10905	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GJD98_RS10950	COG1278	Cold shock
GJD98_RS10955	COG0513	Belongs to the DEAD box helicase family
GJD98_RS10975	COG3158	transport of potassium into the cell
GJD98_RS11010	COG0477	Major facilitator Superfamily
GJD98_RS11020	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GJD98_RS11040	COG0259	pyridoxamine-phosphate oxidase activity
GJD98_RS11045	COG1733	regulation of RNA biosynthetic process
GJD98_RS11050	COG1028	Short-chain dehydrogenase reductase Sdr
GJD98_RS11105	COG1132	(ABC) transporter
GJD98_RS11110	COG1196	nuclear chromosome segregation
GJD98_RS11115	COG1196	nuclear chromosome segregation
GJD98_RS11120	COG1413	lyase activity
GJD98_RS11125	COG1196	nuclear chromosome segregation
GJD98_RS11130	COG1196	nuclear chromosome segregation
GJD98_RS11160	COG4977	sequence-specific DNA binding
GJD98_RS11205	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
GJD98_RS11225	COG0076	glutamate decarboxylase activity
GJD98_RS11240	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GJD98_RS11245	COG2205	protein histidine kinase activity
GJD98_RS11245	COG0784	Response regulator, receiver
GJD98_RS11250	COG0784	Response regulator, receiver
GJD98_RS11250	COG2198	Histidine kinase
GJD98_RS11250	COG5002	protein histidine kinase activity
GJD98_RS11255	COG4106	trans-aconitate 2-methyltransferase activity
GJD98_RS11285	COG0861	Integral membrane protein TerC family
GJD98_RS11300	COG0071	Belongs to the small heat shock protein (HSP20) family
GJD98_RS11310	COG0288	reversible hydration of carbon dioxide
GJD98_RS11390	COG0604	alcohol dehydrogenase
GJD98_RS11420	COG1090	epimerase
GJD98_RS11440	COG4638	Rieske (2fe-2S)
GJD98_RS11455	COG2171	N-acyltransferase activity
GJD98_RS11485	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GJD98_RS11490	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GJD98_RS11500	COG0318	PFAM AMP-dependent synthetase and ligase
GJD98_RS11510	COG1028	Short-chain dehydrogenase reductase Sdr
GJD98_RS11515	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GJD98_RS11520	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GJD98_RS11525	COG2814	Major facilitator Superfamily
GJD98_RS11540	COG1132	(ABC) transporter
GJD98_RS11580	COG1301	dicarboxylic acid transport
GJD98_RS11590	COG0586	Pfam SNARE associated Golgi protein
GJD98_RS11600	COG0519	Catalyzes the synthesis of GMP from XMP
GJD98_RS11615	COG0174	glutamine synthetase
GJD98_RS11635	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
GJD98_RS11650	COG2823	Periplasmic or secreted lipoprotein
GJD98_RS11655	COG3243	poly(R)-hydroxyalkanoic acid synthase
GJD98_RS11665	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GJD98_RS11725	COG0584	glycerophosphoryl diester phosphodiesterase
GJD98_RS11745	COG3185	4-Hydroxyphenylpyruvate dioxygenase
GJD98_RS11755	COG0625	glutathione transferase activity
GJD98_RS11775	COG1136	(ABC) transporter
GJD98_RS11780	COG4591	ABC-type transport system involved in lipoprotein release permease component
GJD98_RS11790	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GJD98_RS11820	COG0546	phosphoglycolate phosphatase activity
GJD98_RS11825	COG0564	pseudouridine synthase activity
GJD98_RS11835	COG1530	ribonuclease E activity
GJD98_RS11845	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GJD98_RS11860	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GJD98_RS11870	COG2890	protein-(glutamine-N5) methyltransferase activity
GJD98_RS11875	COG1193	negative regulation of DNA recombination
GJD98_RS11880	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GJD98_RS11890	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
GJD98_RS11895	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GJD98_RS11935	COG1028	Short-chain dehydrogenase reductase Sdr
GJD98_RS11960	COG0814	amino acid
GJD98_RS12005	COG0142	geranyltranstransferase activity
GJD98_RS12010	COG2226	methyltransferase
GJD98_RS12015	COG1040	competence protein
GJD98_RS12040	COG2890	protein-(glutamine-N5) methyltransferase activity
GJD98_RS12045	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GJD98_RS12055	COG1519	Transferase
GJD98_RS12060	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GJD98_RS12070	COG3240	lipase activity
GJD98_RS12085	COG0513	Belongs to the DEAD box helicase family
GJD98_RS12090	COG1597	lipid kinase activity
GJD98_RS12095	COG1902	pentaerythritol trinitrate reductase activity
GJD98_RS12095	COG0446	pyridine nucleotide-disulphide oxidoreductase
GJD98_RS12100	COG2032	superoxide dismutase activity
GJD98_RS12110	COG0450	alkyl hydroperoxide reductase
GJD98_RS12125	COG0494	nUDIX hydrolase
GJD98_RS12130	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GJD98_RS12135	COG0154	amidase activity
GJD98_RS12140	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GJD98_RS12145	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GJD98_RS12160	COG0358	DNA primase activity
GJD98_RS12210	COG3550	peptidyl-serine autophosphorylation
GJD98_RS12215	COG3550	peptidyl-serine autophosphorylation
GJD98_RS12280	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GJD98_RS12290	COG0583	DNA-binding transcription factor activity
GJD98_RS12295	COG3158	transport of potassium into the cell
GJD98_RS12320	COG0531	amino acid
GJD98_RS12325	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
GJD98_RS12330	COG0477	Major facilitator Superfamily
GJD98_RS12590	COG0435	Glutathione S-transferase
GJD98_RS12635	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
GJD98_RS12680	COG4565	transcriptional regulatory protein
GJD98_RS12685	COG4251	negative regulation of phosphorylation
GJD98_RS12750	COG0309	Hydrogenase expression formation protein (HypE)
GJD98_RS12765	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
GJD98_RS12785	COG0463	Glycosyl transferase, family 2
GJD98_RS12800	COG0697	spore germination
GJD98_RS12810	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GJD98_RS12815	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GJD98_RS12825	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GJD98_RS12830	COG0756	dUTP diphosphatase activity
GJD98_RS12835	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GJD98_RS12840	COG2003	Belongs to the UPF0758 family
GJD98_RS12875	COG5310	Homospermidine synthase
GJD98_RS12880	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GJD98_RS12910	COG0288	reversible hydration of carbon dioxide
GJD98_RS12915	COG0477	Major facilitator Superfamily
GJD98_RS12940	COG2205	protein histidine kinase activity
GJD98_RS12940	COG0784	Response regulator, receiver
GJD98_RS12950	COG1413	lyase activity
GJD98_RS12955	COG1196	nuclear chromosome segregation
GJD98_RS12975	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GJD98_RS12995	COG1522	sequence-specific DNA binding
GJD98_RS13080	COG0436	Aminotransferase
GJD98_RS13090	COG1959	2 iron, 2 sulfur cluster binding
GJD98_RS13120	COG1970	mechanosensitive ion channel activity
GJD98_RS13155	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GJD98_RS13295	COG3189	MarR family transcriptional regulator
GJD98_RS13320	COG1960	acyl-CoA dehydrogenase activity
GJD98_RS13350	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
GJD98_RS13370	COG2027	D-alanyl-D-alanine carboxypeptidase
GJD98_RS13375	COG1475	DNA binding
GJD98_RS13395	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GJD98_RS13410	COG0758	DNA mediated transformation
GJD98_RS13460	COG3590	peptidase
GJD98_RS13470	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GJD98_RS13485	COG1181	Belongs to the D-alanine--D-alanine ligase family
GJD98_RS13490	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GJD98_RS13495	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GJD98_RS13500	COG0772	Belongs to the SEDS family
GJD98_RS13505	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GJD98_RS13510	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GJD98_RS13515	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GJD98_RS13520	COG3115	cell septum assembly
GJD98_RS13525	COG1196	nuclear chromosome segregation
GJD98_RS13550	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GJD98_RS13560	COG2081	HI0933 family
GJD98_RS13570	COG0795	lipopolysaccharide-transporting ATPase activity
GJD98_RS13575	COG0795	lipopolysaccharide-transporting ATPase activity
GJD98_RS13585	COG2927	DNA polymerase III (CHI subunit)
GJD98_RS13595	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GJD98_RS13630	COG1376	ErfK ybiS ycfS ynhG family protein
GJD98_RS13650	COG0322	excinuclease ABC activity
GJD98_RS13655	COG2197	response regulator
GJD98_RS13670	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GJD98_RS13690	COG0193	aminoacyl-tRNA hydrolase activity
GJD98_RS13695	COG0012	GTP binding
GJD98_RS13700	COG5001	Diguanylate cyclase
GJD98_RS13700	COG3300	MHYT domain
GJD98_RS13705	COG0142	geranyltranstransferase activity
GJD98_RS13715	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GJD98_RS13725	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GJD98_RS13735	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GJD98_RS13740	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GJD98_RS13750	COG0439	Biotin carboxylase
GJD98_RS13770	COG2177	Part of the ABC transporter FtsEX involved in
GJD98_RS13775	COG2884	Cell division ATP-binding protein ftsE
GJD98_RS13780	COG0552	protein localization to endoplasmic reticulum
GJD98_RS13785	COG0612	Peptidase, M16
GJD98_RS13790	COG0612	Peptidase, M16
GJD98_RS13795	COG0742	ribosomal rna small subunit methyltransferase
GJD98_RS13815	COG4085	toxin activity
GJD98_RS13815	COG1525	nuclease
GJD98_RS13815	COG0737	Belongs to the 5'-nucleotidase family
GJD98_RS13820	COG2226	methyltransferase
GJD98_RS13825	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GJD98_RS13830	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GJD98_RS13830	COG1181	Belongs to the D-alanine--D-alanine ligase family
GJD98_RS13845	COG0473	3-isopropylmalate dehydrogenase activity
GJD98_RS13845	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GJD98_RS13885	COG2217	Heavy metal translocating P-type atpase
GJD98_RS13885	COG2608	mercury ion transmembrane transporter activity
GJD98_RS13895	COG2226	methyltransferase
GJD98_RS13905	COG0859	PFAM glycosyl transferase family 9
GJD98_RS13915	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GJD98_RS13925	COG0860	N-Acetylmuramoyl-L-alanine amidase
GJD98_RS13930	COG0802	atpase or kinase
GJD98_RS13935	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GJD98_RS13935	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GJD98_RS13940	COG2969	positive regulation of protein catabolic process
GJD98_RS13945	COG0625	glutathione transferase activity
GJD98_RS13950	COG2857	Cytochrome c1
GJD98_RS13955	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GJD98_RS13960	COG0723	plastoquinol--plastocyanin reductase activity
GJD98_RS13965	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GJD98_RS13980	COG0776	regulation of translation
GJD98_RS13985	COG0072	phenylalanine-tRNA ligase activity
GJD98_RS13985	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GJD98_RS13990	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GJD98_RS14010	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GJD98_RS14035	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
GJD98_RS14055	COG0640	Transcriptional regulator
GJD98_RS14065	COG2860	membrane
GJD98_RS14070	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GJD98_RS14075	COG0343	queuine tRNA-ribosyltransferase activity
GJD98_RS14090	COG0156	8-amino-7-oxononanoate synthase activity
GJD98_RS14110	COG0181	hydroxymethylbilane synthase activity
GJD98_RS14135	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GJD98_RS14145	COG0617	tRNA 3'-terminal CCA addition
GJD98_RS14190	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GJD98_RS14195	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GJD98_RS14200	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GJD98_RS14235	COG4536	flavin adenine dinucleotide binding
GJD98_RS14240	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GJD98_RS14245	COG0537	adenosine 5'-monophosphoramidase activity
GJD98_RS14260	COG1185	polyribonucleotide nucleotidyltransferase activity
GJD98_RS14270	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GJD98_RS14280	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GJD98_RS14285	COG2251	uridine kinase activity
GJD98_RS14285	COG0195	Participates in both transcription termination and antitermination
GJD98_RS14330	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
GJD98_RS14335	COG1034	ATP synthesis coupled electron transport
GJD98_RS14340	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
GJD98_RS14355	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GJD98_RS14380	COG0149	triose-phosphate isomerase activity
GJD98_RS14395	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GJD98_RS14410	COG1534	Rna-binding protein
GJD98_RS14430	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GJD98_RS14445	COG3104	oligopeptide transport
GJD98_RS14460	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GJD98_RS14465	COG0308	aminopeptidase N
GJD98_RS14470	COG2766	serine protein kinase
GJD98_RS14480	COG2719	SpoVR family
GJD98_RS14490	COG2234	aminopeptidase activity
GJD98_RS14500	COG0210	DNA helicase
GJD98_RS14505	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GJD98_RS14520	COG0667	Aldo Keto reductase
GJD98_RS14525	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GJD98_RS14530	COG1217	gtp-binding protein TYPA
GJD98_RS14540	COG0497	DNA recombination
GJD98_RS14550	COG0666	response to abiotic stimulus
GJD98_RS14550	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GJD98_RS14570	COG5113	peptidyl-tyrosine sulfation
GJD98_RS14590	COG2183	response to ionizing radiation
GJD98_RS14595	COG0500	methyltransferase
GJD98_RS14600	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GJD98_RS14610	COG1054	Belongs to the UPF0176 family
GJD98_RS14620	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GJD98_RS14625	COG0477	Major facilitator Superfamily
GJD98_RS14630	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GJD98_RS14635	COG0516	GMP reductase activity
GJD98_RS14670	COG1278	Cold shock
GJD98_RS14700	COG2304	oxidoreductase activity
GJD98_RS14715	COG0714	Associated with various cellular activities
GJD98_RS14725	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GJD98_RS14735	COG1028	Short-chain dehydrogenase reductase Sdr
GJD98_RS14750	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GJD98_RS14765	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GJD98_RS14770	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GJD98_RS14775	COG0730	response to heat
GJD98_RS14780	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
GJD98_RS14790	COG0252	asparaginase activity
GJD98_RS14800	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GJD98_RS14805	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GJD98_RS14815	COG0598	Magnesium transport protein CorA
GJD98_RS14825	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GJD98_RS14830	COG2878	Part of a membrane complex involved in electron transport
GJD98_RS14835	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GJD98_RS14835	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GJD98_RS14840	COG0163	prenyltransferase activity
GJD98_RS14855	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GJD98_RS14860	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
GJD98_RS14860	COG0662	Cupin 2, conserved barrel domain protein
GJD98_RS14880	COG1192	Involved in chromosome partitioning
GJD98_RS14885	COG1475	DNA binding
GJD98_RS14890	COG2852	Protein conserved in bacteria
GJD98_RS14895	COG3293	Transposase
GJD98_RS14910	COG0519	Catalyzes the synthesis of GMP from XMP
GJD98_RS14920	COG1845	cytochrome c oxidase, subunit III
GJD98_RS14925	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
GJD98_RS14930	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GJD98_RS14935	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GJD98_RS14940	COG2010	Cytochrome c
GJD98_RS14965	COG2226	methyltransferase
GJD98_RS14975	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GJD98_RS15000	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GJD98_RS15000	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GJD98_RS15085	COG1136	(ABC) transporter
GJD98_RS15085	COG0577	efflux transmembrane transporter activity
GJD98_RS15105	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GJD98_RS15115	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GJD98_RS15120	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
GJD98_RS15125	COG0805	protein transport
GJD98_RS15140	COG0543	2 iron, 2 sulfur cluster binding
GJD98_RS15140	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GJD98_RS15145	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GJD98_RS15160	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GJD98_RS15180	COG1560	Kdo2-lipid A biosynthetic process
GJD98_RS15195	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GJD98_RS15200	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GJD98_RS15205	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GJD98_RS15215	COG1132	(ABC) transporter
GJD98_RS15270	COG0776	regulation of translation
GJD98_RS15280	COG0330	HflC and HflK could
GJD98_RS15290	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GJD98_RS15320	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GJD98_RS15325	COG0450	alkyl hydroperoxide reductase
GJD98_RS15330	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GJD98_RS15335	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GJD98_RS15340	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GJD98_RS15345	COG1234	tRNA 3'-trailer cleavage
GJD98_RS15355	COG0281	malic enzyme
GJD98_RS15360	COG0009	L-threonylcarbamoyladenylate synthase
GJD98_RS15370	COG0688	phosphatidylethanolamine metabolic process
GJD98_RS15420	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GJD98_RS15435	COG0356	it plays a direct role in the translocation of protons across the membrane
GJD98_RS15450	COG2823	Periplasmic or secreted lipoprotein
GJD98_RS15455	COG2823	Periplasmic or secreted lipoprotein
GJD98_RS15460	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GJD98_RS15465	COG0792	nuclease activity
GJD98_RS15470	COG3107	peptidoglycan biosynthetic process
GJD98_RS15475	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GJD98_RS15500	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GJD98_RS15505	COG0706	membrane insertase activity