locus-tag	class	description
LPV_RS00010	COG0592	DNA-directed DNA polymerase activity
LPV_RS00020	COG0187	DNA topoisomerase II activity
LPV_RS00030	COG1166	arginine decarboxylase activity
LPV_RS00050	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LPV_RS00055	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LPV_RS00065	COG1741	Belongs to the pirin family
LPV_RS00075	COG1566	PFAM secretion protein HlyD family protein
LPV_RS00095	COG3227	Zinc metalloprotease (Elastase)
LPV_RS00105	COG3028	Belongs to the UPF0307 family
LPV_RS00130	COG0531	amino acid
LPV_RS00135	COG0306	phosphate transporter
LPV_RS00145	COG3300	MHYT domain
LPV_RS00145	COG5001	Diguanylate cyclase
LPV_RS00155	COG2234	aminopeptidase activity
LPV_RS00215	COG3781	membrane
LPV_RS00260	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
LPV_RS00280	COG0583	DNA-binding transcription factor activity
LPV_RS00300	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LPV_RS00340	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
LPV_RS00375	COG0436	Aminotransferase
LPV_RS00385	COG2203	Gaf domain
LPV_RS00385	COG4251	negative regulation of phosphorylation
LPV_RS00385	COG5001	Diguanylate cyclase
LPV_RS00385	COG3706	GGDEF domain
LPV_RS00390	COG0069	glutamate synthase activity
LPV_RS00395	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
LPV_RS00400	COG3079	Belongs to the UPF0149 family
LPV_RS00405	COG0006	proline dipeptidase activity
LPV_RS00410	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LPV_RS00415	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LPV_RS00445	COG0189	ligase activity
LPV_RS00445	COG4067	protein conserved in archaea
LPV_RS00480	COG0557	exoribonuclease II activity
LPV_RS00485	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LPV_RS00505	COG2824	Alkylphosphonate utilization operon protein PhnA
LPV_RS00535	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LPV_RS00545	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LPV_RS00555	COG2252	PERMEase
LPV_RS00585	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
LPV_RS00590	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LPV_RS00630	COG1116	anion transmembrane transporter activity
LPV_RS00635	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LPV_RS00655	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LPV_RS00700	COG0469	pyruvate kinase activity
LPV_RS00710	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LPV_RS00715	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LPV_RS00725	COG0339	signal peptide processing
LPV_RS00755	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
LPV_RS00800	COG2948	multi-organism process
LPV_RS00830	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LPV_RS00875	COG0582	viral genome integration into host DNA
LPV_RS00945	COG0582	viral genome integration into host DNA
LPV_RS00955	COG3104	oligopeptide transport
LPV_RS00980	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LPV_RS01015	COG0728	peptidoglycan biosynthetic process
LPV_RS01025	COG3344	reverse transcriptase
LPV_RS01060	COG5001	Diguanylate cyclase
LPV_RS01070	COG0024	Methionine aminopeptidase
LPV_RS01115	COG2354	Protein conserved in bacteria
LPV_RS01120	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LPV_RS01150	COG0583	DNA-binding transcription factor activity
LPV_RS01165	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LPV_RS01170	COG2814	Major facilitator Superfamily
LPV_RS01210	COG1172	Belongs to the binding-protein-dependent transport system permease family
LPV_RS01240	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
LPV_RS01265	COG1271	oxidase subunit
LPV_RS01270	COG1294	oxidase, subunit
LPV_RS01285	COG1307	EDD domain protein, DegV family
LPV_RS01290	COG1028	Short-chain dehydrogenase reductase Sdr
LPV_RS01295	COG3046	protein related to deoxyribodipyrimidine photolyase
LPV_RS01325	COG0415	Belongs to the DNA photolyase family
LPV_RS01330	COG1346	cytolysis
LPV_RS01335	COG1380	Effector of murein hydrolase LrgA
LPV_RS01340	COG0583	DNA-binding transcription factor activity
LPV_RS01370	COG3002	Belongs to the UPF0753 family
LPV_RS01375	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LPV_RS01380	COG0583	DNA-binding transcription factor activity
LPV_RS01385	COG2274	protein secretion by the type I secretion system
LPV_RS01405	COG0531	amino acid
LPV_RS01415	COG3706	GGDEF domain
LPV_RS01420	COG2217	Heavy metal translocating P-type atpase
LPV_RS01425	COG0735	belongs to the Fur family
LPV_RS01435	COG1196	nuclear chromosome segregation
LPV_RS01460	COG1012	belongs to the aldehyde dehydrogenase family
LPV_RS01465	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LPV_RS01485	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LPV_RS01510	COG1393	Belongs to the ArsC family
LPV_RS01520	COG0513	Belongs to the DEAD box helicase family
LPV_RS01530	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
LPV_RS01555	COG1566	PFAM secretion protein HlyD family protein
LPV_RS01590	COG1573	uracil-dna glycosylase
LPV_RS01630	COG0598	Magnesium transport protein CorA
LPV_RS01640	COG0433	COG0433 Predicted ATPase
LPV_RS01645	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LPV_RS01650	COG1335	isochorismatase
LPV_RS01660	COG2814	Major facilitator Superfamily
LPV_RS01665	COG0583	DNA-binding transcription factor activity
LPV_RS01685	COG0642	Histidine kinase
LPV_RS01695	COG0583	DNA-binding transcription factor activity
LPV_RS01710	COG2226	methyltransferase
LPV_RS01730	COG4221	oxidoreductase activity
LPV_RS01745	COG1509	lysine 2,3-aminomutase activity
LPV_RS01780	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LPV_RS01795	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LPV_RS02060	COG0629	single-stranded DNA binding
LPV_RS02065	COG2814	Major facilitator Superfamily
LPV_RS02070	COG1028	Short-chain dehydrogenase reductase Sdr
LPV_RS02080	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LPV_RS02085	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LPV_RS02095	COG1560	Kdo2-lipid A biosynthetic process
LPV_RS02125	COG2867	negative regulation of translational initiation
LPV_RS02130	COG2914	Belongs to the UPF0125 (RnfH) family
LPV_RS02135	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LPV_RS02140	COG0735	belongs to the Fur family
LPV_RS02170	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
LPV_RS02205	COG1704	LemA family
LPV_RS02215	COG0842	Transport permease protein
LPV_RS02220	COG1131	(ABC) transporter
LPV_RS02250	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LPV_RS02275	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LPV_RS02295	COG0531	amino acid
LPV_RS02315	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
LPV_RS02335	COG1612	heme a metabolic process
LPV_RS02345	COG1999	signal sequence binding
LPV_RS02360	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LPV_RS02370	COG0129	dihydroxy-acid dehydratase activity
LPV_RS02375	COG0837	glucose binding
LPV_RS02380	COG0800	Aldolase
LPV_RS02385	COG2814	Major facilitator Superfamily
LPV_RS02395	COG3655	Transcriptional regulator
LPV_RS02410	COG1278	Cold shock
LPV_RS02430	COG1566	PFAM secretion protein HlyD family protein
LPV_RS02445	COG1733	regulation of RNA biosynthetic process
LPV_RS02565	COG0477	Major facilitator Superfamily
LPV_RS02590	COG0439	Biotin carboxylase
LPV_RS02595	COG0511	ligase activity, forming carbon-carbon bonds
LPV_RS02605	COG0511	ligase activity, forming carbon-carbon bonds
LPV_RS02605	COG5016	pyruvate
LPV_RS02615	COG3227	Zinc metalloprotease (Elastase)
LPV_RS02625	COG3568	Endonuclease Exonuclease Phosphatase
LPV_RS02630	COG3588	fructose-bisphosphate aldolase
LPV_RS02650	COG1183	phosphatidylcholine synthase activity
LPV_RS02660	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LPV_RS02665	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
LPV_RS02685	COG1363	Peptidase, m42
LPV_RS02695	COG0330	HflC and HflK could
LPV_RS02700	COG0330	HflC and HflK could
LPV_RS02705	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LPV_RS02715	COG1438	arginine binding
LPV_RS02720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LPV_RS02725	COG0765	amino acid transport
LPV_RS02730	COG1126	abc transporter atp-binding protein
LPV_RS02745	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LPV_RS02760	COG0793	Belongs to the peptidase S41A family
LPV_RS02765	COG4942	peptidase
LPV_RS02785	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LPV_RS02790	COG0575	Belongs to the CDS family
LPV_RS02810	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LPV_RS02820	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LPV_RS02855	COG0656	L-ascorbic acid biosynthetic process
LPV_RS02880	COG0572	uridine kinase
LPV_RS02925	COG2009	succinate dehydrogenase
LPV_RS02930	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
LPV_RS02935	COG1053	succinate dehydrogenase
LPV_RS02940	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LPV_RS02950	COG0508	dehydrogenase complex catalyzes the overall conversion of
LPV_RS02960	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LPV_RS02980	COG2814	Major facilitator Superfamily
LPV_RS02990	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
LPV_RS02995	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LPV_RS03005	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
LPV_RS03020	COG2072	flavoprotein involved in K transport
LPV_RS03050	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LPV_RS03070	COG1028	Short-chain dehydrogenase reductase Sdr
LPV_RS03075	COG1028	Short-chain dehydrogenase reductase Sdr
LPV_RS03095	COG2715	membrane protein required for spore maturation
LPV_RS03100	COG0700	Nucleoside recognition
LPV_RS03105	COG0739	heme binding
LPV_RS03110	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LPV_RS03140	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LPV_RS03145	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LPV_RS03150	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LPV_RS03165	COG0306	phosphate transporter
LPV_RS03170	COG1392	Phosphate transport regulator
LPV_RS03185	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LPV_RS03205	COG0606	chelatase, subunit chli
LPV_RS03215	COG0347	Belongs to the P(II) protein family
LPV_RS03220	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LPV_RS03255	COG3243	poly(R)-hydroxyalkanoic acid synthase
LPV_RS03260	COG1959	2 iron, 2 sulfur cluster binding
LPV_RS03265	COG0719	Fe-S assembly protein
LPV_RS03270	COG0396	ATPase activity
LPV_RS03275	COG0719	Fe-S assembly protein
LPV_RS03280	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LPV_RS03285	COG0822	iron-sulfur transferase activity
LPV_RS03290	COG2151	metal-sulfur cluster biosynthetic enzyme
LPV_RS03295	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
LPV_RS03300	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
LPV_RS03305	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LPV_RS03315	COG1253	flavin adenine dinucleotide binding
LPV_RS03320	COG1064	alcohol dehydrogenase
LPV_RS03355	COG0519	Catalyzes the synthesis of GMP from XMP
LPV_RS03470	COG5433	transposase activity
LPV_RS03510	COG2852	Protein conserved in bacteria
LPV_RS03515	COG0708	Exodeoxyribonuclease III
LPV_RS03520	COG0708	Exodeoxyribonuclease III
LPV_RS03530	COG0281	malic enzyme
LPV_RS03545	COG0338	D12 class N6 adenine-specific DNA methyltransferase
LPV_RS03550	COG0814	amino acid
LPV_RS03555	COG0814	amino acid
LPV_RS03570	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LPV_RS03575	COG1131	(ABC) transporter
LPV_RS03580	COG0842	Transport permease protein
LPV_RS03585	COG0842	Transport permease protein
LPV_RS03595	COG0741	lytic transglycosylase activity
LPV_RS03600	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LPV_RS03615	COG3220	belongs to the UPF0276 family
LPV_RS03635	COG4689	acetoacetate decarboxylase
LPV_RS03655	COG3220	belongs to the UPF0276 family
LPV_RS03685	COG1131	(ABC) transporter
LPV_RS03700	COG5433	transposase activity
LPV_RS03705	COG4232	protein-disulfide reductase activity
LPV_RS03720	COG0783	Belongs to the Dps family
LPV_RS03725	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LPV_RS03730	COG3328	transposase activity
LPV_RS03740	COG0187	DNA topoisomerase II activity
LPV_RS03760	COG0666	response to abiotic stimulus
LPV_RS03760	COG3177	Filamentation induced by cAMP protein fic
LPV_RS03765	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
LPV_RS03770	COG0659	secondary active sulfate transmembrane transporter activity
LPV_RS03780	COG1538	Outer membrane efflux protein
LPV_RS03785	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LPV_RS03790	COG0156	8-amino-7-oxononanoate synthase activity
LPV_RS03795	COG1063	alcohol dehydrogenase
LPV_RS03800	COG0488	(ABC) transporter
LPV_RS03850	COG1297	OPT oligopeptide transporter protein
LPV_RS03860	COG5002	protein histidine kinase activity
LPV_RS03880	COG1823	symporter activity
LPV_RS03890	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LPV_RS03895	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LPV_RS03930	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LPV_RS03935	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LPV_RS03940	COG0628	permease
LPV_RS03965	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LPV_RS03975	COG0305	Participates in initiation and elongation during chromosome replication
LPV_RS04015	COG2827	Endonuclease containing a URI domain
LPV_RS04020	COG3104	oligopeptide transport
LPV_RS04025	COG5433	transposase activity
LPV_RS04040	COG0107	imidazoleglycerol-phosphate synthase activity
LPV_RS04050	COG1083	cytidylyl-transferase
LPV_RS04055	COG2089	acid synthase
LPV_RS04060	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LPV_RS04070	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LPV_RS04085	COG1088	dTDP-glucose 4,6-dehydratase activity
LPV_RS04105	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LPV_RS04140	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
LPV_RS04150	COG3344	reverse transcriptase
LPV_RS04160	COG5433	transposase activity
LPV_RS04215	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
LPV_RS04215	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
LPV_RS04220	COG2091	lysine biosynthetic process via aminoadipic acid
LPV_RS04230	COG0037	tRNA processing
LPV_RS04245	COG1696	Membrane protein involved in D-alanine export
LPV_RS04250	COG1760	l-serine dehydratase
LPV_RS04255	COG0545	Peptidyl-prolyl cis-trans isomerase
LPV_RS04260	COG2223	nitrite transmembrane transporter activity
LPV_RS04275	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LPV_RS04280	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
LPV_RS04285	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LPV_RS04290	COG0659	secondary active sulfate transmembrane transporter activity
LPV_RS04295	COG1960	acyl-CoA dehydrogenase activity
LPV_RS04305	COG0574	Belongs to the PEP-utilizing enzyme family
LPV_RS04305	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LPV_RS04310	COG0475	glutathione-regulated potassium exporter activity
LPV_RS04325	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LPV_RS04330	COG1555	photosystem II stabilization
LPV_RS04335	COG1077	Cell shape determining protein MreB Mrl
LPV_RS04340	COG1792	Involved in formation and maintenance of cell shape
LPV_RS04345	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
LPV_RS04350	COG1187	pseudouridine synthase activity
LPV_RS04370	COG0542	response to heat
LPV_RS04400	COG0705	Rhomboid family
LPV_RS04405	COG0739	heme binding
LPV_RS04455	COG0512	Glutamine amidotransferase of anthranilate synthase
LPV_RS04460	COG1137	ATPase activity
LPV_RS04475	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
LPV_RS04485	COG1127	ABC transporter
LPV_RS04490	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LPV_RS04495	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LPV_RS04510	COG5007	Belongs to the BolA IbaG family
LPV_RS04525	COG1136	(ABC) transporter
LPV_RS04530	COG0577	efflux transmembrane transporter activity
LPV_RS04535	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LPV_RS04555	COG0616	signal peptide processing
LPV_RS04585	COG1138	Cytochrome C-type biogenesis protein
LPV_RS04605	COG3360	Dodecin
LPV_RS04620	COG0514	ATP-dependent DNA helicase (RecQ)
LPV_RS04625	COG1960	acyl-CoA dehydrogenase activity
LPV_RS04630	COG1024	Enoyl-CoA hydratase
LPV_RS04635	COG1024	Enoyl-CoA hydratase
LPV_RS04670	COG2340	Cysteine-rich secretory protein family
LPV_RS04680	COG3706	GGDEF domain
LPV_RS04705	COG1472	Belongs to the glycosyl hydrolase 3 family
LPV_RS04725	COG0204	Acyl-transferase
LPV_RS04730	COG0626	cystathionine gamma-synthase activity
LPV_RS04775	COG1194	a g-specific adenine glycosylase
LPV_RS04805	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LPV_RS04830	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
LPV_RS04880	COG1994	Peptidase M50
LPV_RS04905	COG0686	Belongs to the AlaDH PNT family
LPV_RS04960	COG0589	response to stress
LPV_RS04965	COG0196	riboflavin kinase activity
LPV_RS04980	COG0800	Aldolase
LPV_RS04995	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LPV_RS05020	COG0674	pyruvate-flavodoxin oxidoreductase activity
LPV_RS05020	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
LPV_RS05025	COG1013	pyruvate-flavodoxin oxidoreductase activity
LPV_RS05030	COG0670	Belongs to the BI1 family
LPV_RS05035	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LPV_RS05040	COG0312	modulator of DNA gyrase
LPV_RS05045	COG1752	Esterase of the alpha-beta hydrolase superfamily
LPV_RS05050	COG1022	Amp-dependent synthetase and ligase
LPV_RS05055	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LPV_RS05075	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LPV_RS05085	COG0601	transmembrane transport
LPV_RS05090	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LPV_RS05105	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
LPV_RS05135	COG0833	amino acid
LPV_RS05160	COG2135	peptidase activity
LPV_RS05165	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LPV_RS05190	COG0629	single-stranded DNA binding
LPV_RS05315	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
LPV_RS05340	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LPV_RS05355	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LPV_RS05360	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
LPV_RS05370	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LPV_RS05375	COG2217	Heavy metal translocating P-type atpase
LPV_RS05380	COG2203	Gaf domain
LPV_RS05380	COG2199	diguanylate cyclase activity
LPV_RS05420	COG2026	Addiction module toxin, RelE StbE family
LPV_RS05435	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LPV_RS05460	COG2132	Multicopper oxidase
LPV_RS05480	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LPV_RS05505	COG0640	Transcriptional regulator
LPV_RS05535	COG1028	Short-chain dehydrogenase reductase Sdr
LPV_RS05540	COG1278	Cold shock
LPV_RS05555	COG0242	peptide deformylase activity
LPV_RS05580	COG0582	viral genome integration into host DNA
LPV_RS05610	COG3311	Transcriptional regulator
LPV_RS05615	COG1569	PIN domain
LPV_RS05620	COG0582	viral genome integration into host DNA
LPV_RS05635	COG3177	Filamentation induced by cAMP protein fic
LPV_RS05645	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LPV_RS05660	COG3344	reverse transcriptase
LPV_RS05695	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LPV_RS05695	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LPV_RS05735	COG3293	Transposase
LPV_RS05760	COG4251	negative regulation of phosphorylation
LPV_RS05765	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
LPV_RS05800	COG0741	lytic transglycosylase activity
LPV_RS05800	COG1388	LysM domain
LPV_RS05815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LPV_RS05830	COG0590	tRNA wobble adenosine to inosine editing
LPV_RS05850	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LPV_RS05860	COG2070	2-Nitropropane dioxygenase
LPV_RS05890	COG1177	transmembrane transport
LPV_RS05895	COG1176	ABC-type spermidine putrescine transport system, permease component I
LPV_RS05925	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
LPV_RS05960	COG1231	oxidoreductase activity
LPV_RS05970	COG3961	Belongs to the TPP enzyme family
LPV_RS05990	COG0697	spore germination
LPV_RS06015	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LPV_RS06040	COG1355	regulation of microtubule-based process
LPV_RS06080	COG4783	chaperone-mediated protein folding
LPV_RS06085	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LPV_RS06085	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LPV_RS06090	COG0307	riboflavin synthase, alpha
LPV_RS06095	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LPV_RS06095	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LPV_RS06120	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
LPV_RS06135	COG2974	May be involved in recombination
LPV_RS06150	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LPV_RS06155	COG1472	Belongs to the glycosyl hydrolase 3 family
LPV_RS06165	COG0140	phosphoribosyl-ATP diphosphatase activity
LPV_RS06165	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LPV_RS06170	COG0107	imidazoleglycerol-phosphate synthase activity
LPV_RS06200	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
LPV_RS06210	COG1271	oxidase subunit
LPV_RS06215	COG1294	oxidase, subunit
LPV_RS06230	COG1278	Cold shock
LPV_RS06240	COG0442	prolyl-tRNA aminoacylation
LPV_RS06245	COG1846	Transcriptional regulator
LPV_RS06260	COG1280	lysine exporter protein (LysE YggA)
LPV_RS06285	COG1815	bacterial-type flagellum-dependent cell motility
LPV_RS06295	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
LPV_RS06300	COG1749	Flagellar hook protein flgE
LPV_RS06305	COG4787	bacterial-type flagellum-dependent cell motility
LPV_RS06310	COG4786	Flagellar basal body rod
LPV_RS06320	COG1706	bacterial-type flagellum-dependent cell motility
LPV_RS06345	COG2826	transposase and inactivated derivatives, IS30 family
LPV_RS06365	COG0471	metal ion transport
LPV_RS06365	COG3273	potassium ion transport
LPV_RS06375	COG1132	(ABC) transporter
LPV_RS06390	COG0281	malic enzyme
LPV_RS06415	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
LPV_RS06440	COG0642	Histidine kinase
LPV_RS06455	COG0741	lytic transglycosylase activity
LPV_RS06455	COG1388	LysM domain
LPV_RS06470	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
LPV_RS06500	COG1090	epimerase
LPV_RS06525	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LPV_RS06535	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LPV_RS06565	COG0673	inositol 2-dehydrogenase activity
LPV_RS06570	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
LPV_RS06575	COG2814	Major facilitator Superfamily
LPV_RS06580	COG2814	Major facilitator Superfamily
LPV_RS06585	COG4264	IucA IucC family
LPV_RS06620	COG1496	oxidoreductase activity
LPV_RS06670	COG0285	dihydrofolate synthase activity
LPV_RS06680	COG1286	toxin biosynthetic process
LPV_RS06705	COG0815	Transfers the fatty acyl group on membrane lipoproteins
LPV_RS06715	COG1012	belongs to the aldehyde dehydrogenase family
LPV_RS06720	COG1250	3-hydroxyacyl-CoA dehydrogenase
LPV_RS06720	COG1024	Enoyl-CoA hydratase
LPV_RS06725	COG0183	Belongs to the thiolase family
LPV_RS06750	COG3156	type II secretion system protein K
LPV_RS06770	COG2165	general secretion pathway protein
LPV_RS06780	COG0174	glutamine synthetase
LPV_RS06795	COG2515	1-aminocyclopropane-1-carboxylate deaminase
LPV_RS06810	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
LPV_RS06820	COG0673	inositol 2-dehydrogenase activity
LPV_RS06830	COG0772	Belongs to the SEDS family
LPV_RS06835	COG0768	penicillin binding
LPV_RS06860	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
LPV_RS06875	COG0300	oxidoreductase activity
LPV_RS06885	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LPV_RS06930	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LPV_RS06935	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LPV_RS06940	COG1028	Short-chain dehydrogenase reductase Sdr
LPV_RS06945	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LPV_RS06950	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LPV_RS06955	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LPV_RS06965	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LPV_RS06975	COG0084	hydrolase, TatD family'
LPV_RS06995	COG0463	Glycosyl transferase, family 2
LPV_RS07025	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LPV_RS07035	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LPV_RS07040	COG0372	Belongs to the citrate synthase family
LPV_RS07065	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
LPV_RS07080	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
LPV_RS07135	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
LPV_RS07140	COG0295	cytidine deaminase activity
LPV_RS07155	COG0745	RESPONSE REGULATOR receiver
LPV_RS07160	COG4535	Mg2 and Co2 transporter CorC
LPV_RS07170	COG1702	phosphate starvation-inducible protein PhoH
LPV_RS07175	COG0613	PHP domain protein
LPV_RS07180	COG0009	L-threonylcarbamoyladenylate synthase
LPV_RS07185	COG0180	Tryptophanyl-tRNA synthetase
LPV_RS07195	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LPV_RS07200	COG1187	pseudouridine synthase activity
LPV_RS07220	COG1881	PFAM PEBP family protein
LPV_RS07255	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LPV_RS07265	COG0436	Aminotransferase
LPV_RS07275	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LPV_RS07280	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LPV_RS07290	COG0494	nUDIX hydrolase
LPV_RS07315	COG0237	dephospho-CoA kinase activity
LPV_RS07325	COG2200	EAL domain
LPV_RS07335	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LPV_RS07345	COG0156	8-amino-7-oxononanoate synthase activity
LPV_RS07375	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
LPV_RS07375	COG3264	Mechanosensitive ion channel
LPV_RS07410	COG1522	sequence-specific DNA binding
LPV_RS07465	COG1196	nuclear chromosome segregation
LPV_RS07470	COG0308	aminopeptidase N
LPV_RS07505	COG0456	acetyltransferase
LPV_RS07510	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LPV_RS07515	COG0508	dehydrogenase complex catalyzes the overall conversion of
LPV_RS07530	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
LPV_RS07535	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LPV_RS07535	COG0475	glutathione-regulated potassium exporter activity
LPV_RS07540	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LPV_RS07545	COG1686	Belongs to the peptidase S11 family
LPV_RS07555	COG2921	Belongs to the UPF0250 family
LPV_RS07575	COG3034	peptidoglycan biosynthetic process
LPV_RS07580	COG2274	protein secretion by the type I secretion system
LPV_RS07590	COG5001	Diguanylate cyclase
LPV_RS07590	COG4251	negative regulation of phosphorylation
LPV_RS07590	COG3706	GGDEF domain
LPV_RS07590	COG2203	Gaf domain
LPV_RS07595	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
LPV_RS07620	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
LPV_RS07650	COG0372	Belongs to the citrate synthase family
LPV_RS07680	COG1981	membrane
LPV_RS07685	COG0861	Integral membrane protein TerC family
LPV_RS07690	COG0617	tRNA 3'-terminal CCA addition
LPV_RS07695	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LPV_RS07700	COG0589	response to stress
LPV_RS07730	COG3063	Type IV pilus biogenesis stability protein PilW
LPV_RS07735	COG0820	rRNA (adenine-C2-)-methyltransferase activity
LPV_RS07745	COG5433	transposase activity
LPV_RS07765	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LPV_RS07770	COG0850	regulation of cytokinetic process
LPV_RS07775	COG0318	PFAM AMP-dependent synthetase and ligase
LPV_RS07780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LPV_RS07790	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LPV_RS07810	COG3264	Mechanosensitive ion channel
LPV_RS07810	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
LPV_RS07815	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LPV_RS07830	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LPV_RS07850	COG0352	thiamine-phosphate diphosphorylase activity
LPV_RS07885	COG0824	Thioesterase
LPV_RS07915	COG3038	cytochrome b561
LPV_RS07920	COG2902	Dehydrogenase
LPV_RS07925	COG1376	ErfK ybiS ycfS ynhG family protein
LPV_RS07930	COG1012	belongs to the aldehyde dehydrogenase family
LPV_RS07935	COG1183	phosphatidylcholine synthase activity
LPV_RS07990	COG1376	ErfK ybiS ycfS ynhG family protein
LPV_RS07990	COG1388	LysM domain
LPV_RS07995	COG1024	Enoyl-CoA hydratase
LPV_RS07995	COG1250	3-hydroxyacyl-CoA dehydrogenase
LPV_RS08000	COG0183	Belongs to the thiolase family
LPV_RS08020	COG0582	viral genome integration into host DNA
LPV_RS08030	COG0477	Major facilitator Superfamily
LPV_RS08040	COG2267	carboxylic ester hydrolase activity
LPV_RS08060	COG1278	Cold shock
LPV_RS08065	COG1028	Short-chain dehydrogenase reductase Sdr
LPV_RS08100	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LPV_RS08115	COG0356	it plays a direct role in the translocation of protons across the membrane
LPV_RS08125	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LPV_RS08125	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LPV_RS08140	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LPV_RS08170	COG0840	transmembrane signaling receptor activity
LPV_RS08205	COG0640	Transcriptional regulator
LPV_RS08230	COG2132	Multicopper oxidase
LPV_RS08260	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LPV_RS08275	COG2203	Gaf domain
LPV_RS08275	COG2199	diguanylate cyclase activity
LPV_RS08280	COG2217	Heavy metal translocating P-type atpase
LPV_RS08305	COG2217	Heavy metal translocating P-type atpase
LPV_RS08310	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LPV_RS08320	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
LPV_RS08325	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LPV_RS08340	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LPV_RS08500	COG0582	viral genome integration into host DNA
LPV_RS08530	COG5654	RES domain protein
LPV_RS08540	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
LPV_RS08545	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
LPV_RS08550	COG0494	nUDIX hydrolase
LPV_RS08560	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LPV_RS08565	COG0789	Transcriptional regulator
LPV_RS08580	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LPV_RS08580	COG0456	acetyltransferase
LPV_RS08585	COG1132	(ABC) transporter
LPV_RS08590	COG0488	(ABC) transporter
LPV_RS08605	COG0768	penicillin binding
LPV_RS08630	COG0429	hydrolase of the alpha beta-hydrolase fold
LPV_RS08645	COG2217	Heavy metal translocating P-type atpase
LPV_RS08670	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LPV_RS08675	COG0438	transferase activity, transferring glycosyl groups
LPV_RS08685	COG0247	lactate metabolic process
LPV_RS08685	COG0277	FAD linked oxidase domain protein
LPV_RS08705	COG0477	Major facilitator Superfamily
LPV_RS08715	COG2119	membrane
LPV_RS08720	COG0823	Involved in the tonB-independent uptake of proteins
LPV_RS08730	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LPV_RS08745	COG3038	cytochrome b561
LPV_RS08750	COG2353	YceI-like domain
LPV_RS08760	COG1082	Xylose isomerase domain protein TIM barrel
LPV_RS08770	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LPV_RS08775	COG0673	inositol 2-dehydrogenase activity
LPV_RS08780	COG2814	Major facilitator Superfamily
LPV_RS08805	COG0531	amino acid
LPV_RS08835	COG4953	penicillin-binding protein 1C
LPV_RS08840	COG2373	Large extracellular alpha-helical protein
LPV_RS08850	COG5433	transposase activity
LPV_RS08890	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LPV_RS08895	COG0151	Belongs to the GarS family
LPV_RS08915	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LPV_RS08920	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LPV_RS08935	COG4232	protein-disulfide reductase activity
LPV_RS08940	COG0300	oxidoreductase activity
LPV_RS08970	COG3144	bacterial-type flagellum assembly
LPV_RS08980	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LPV_RS08985	COG0531	amino acid
LPV_RS09000	COG0463	Glycosyl transferase, family 2
LPV_RS09050	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LPV_RS09055	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LPV_RS09065	COG3138	arginine N-succinyltransferase
LPV_RS09095	COG0528	UMP kinase activity
LPV_RS09155	COG2894	cell division
LPV_RS09165	COG1960	acyl-CoA dehydrogenase activity
LPV_RS09170	COG2267	carboxylic ester hydrolase activity
LPV_RS09180	COG3842	ATPase activity
LPV_RS09185	COG0395	ABC-type sugar transport system, permease component
LPV_RS09190	COG1175	transmembrane transport
LPV_RS09195	COG1063	alcohol dehydrogenase
LPV_RS09200	COG0038	chloride channel
LPV_RS09205	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LPV_RS09205	COG0512	Glutamine amidotransferase of anthranilate synthase
LPV_RS09210	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LPV_RS09220	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LPV_RS09225	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LPV_RS09250	COG0316	Belongs to the HesB IscA family
LPV_RS09260	COG1104	cysteine desulfurase activity
LPV_RS09265	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
LPV_RS09275	COG0616	signal peptide processing
LPV_RS09280	COG0542	response to heat
LPV_RS09285	COG2801	Transposase and inactivated derivatives
LPV_RS09300	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LPV_RS09330	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LPV_RS09340	COG1677	Flagellar hook-basal body complex protein FliE
LPV_RS09355	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LPV_RS09365	COG1674	ftsk spoiiie
LPV_RS09370	COG0492	ferredoxin-NADP+ reductase activity
LPV_RS09380	COG0425	Belongs to the sulfur carrier protein TusA family
LPV_RS09380	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LPV_RS09390	COG0312	modulator of DNA gyrase
LPV_RS09405	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LPV_RS09405	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LPV_RS09440	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LPV_RS09515	COG0583	DNA-binding transcription factor activity
LPV_RS09570	COG2911	Protein conserved in bacteria
LPV_RS09575	COG0113	porphobilinogen synthase activity
LPV_RS09590	COG0527	aspartate kinase activity
LPV_RS09600	COG0489	protein tyrosine kinase activity
LPV_RS09610	COG0583	DNA-binding transcription factor activity
LPV_RS09615	COG2814	Major facilitator Superfamily
LPV_RS09630	COG1132	(ABC) transporter
LPV_RS09655	COG1960	acyl-CoA dehydrogenase activity
LPV_RS09660	COG0183	Belongs to the thiolase family
LPV_RS09670	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LPV_RS09675	COG1024	Enoyl-CoA hydratase
LPV_RS09690	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LPV_RS09705	COG2011	ABC-type metal ion transport system permease component
LPV_RS09710	COG1464	Belongs to the NlpA lipoprotein family
LPV_RS09725	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LPV_RS09730	COG0751	glycine-tRNA ligase activity
LPV_RS09745	COG0210	DNA helicase
LPV_RS09765	COG0189	ligase activity
LPV_RS09785	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LPV_RS09795	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
LPV_RS09800	COG0572	uridine kinase
LPV_RS09830	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LPV_RS09875	COG0488	(ABC) transporter
LPV_RS09900	COG2951	lytic endotransglycosylase activity
LPV_RS09910	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
LPV_RS09955	COG0346	lactoylglutathione lyase activity
LPV_RS09995	COG0657	acetylesterase activity
LPV_RS10015	COG2223	nitrite transmembrane transporter activity
LPV_RS10020	COG0038	chloride channel
LPV_RS10030	COG3012	SEC-C Motif Domain Protein
LPV_RS10040	COG2850	peptidyl-arginine hydroxylation
LPV_RS10060	COG3101	peptidyl-lysine hydroxylation
LPV_RS10070	COG0625	glutathione transferase activity
LPV_RS10095	COG0205	6-phosphofructokinase activity
LPV_RS10100	COG4969	Belongs to the N-Me-Phe pilin family
LPV_RS10105	COG4969	Belongs to the N-Me-Phe pilin family
LPV_RS10115	COG0531	amino acid
LPV_RS10120	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
LPV_RS10135	COG1214	PFAM Peptidase M22, glycoprotease
LPV_RS10140	COG1199	ATP-dependent helicase activity
LPV_RS10145	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
LPV_RS10170	COG2313	pseudouridylate synthase activity
LPV_RS10215	COG0582	viral genome integration into host DNA
LPV_RS10300	COG1250	3-hydroxyacyl-CoA dehydrogenase
LPV_RS10315	COG5212	phosphodiesterase
LPV_RS10345	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LPV_RS10365	COG4948	Mandelate Racemase Muconate Lactonizing
LPV_RS10485	COG3774	pathogenesis
LPV_RS10530	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LPV_RS10560	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
LPV_RS10590	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LPV_RS10595	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LPV_RS10600	COG1862	Preprotein translocase
LPV_RS10605	COG0343	queuine tRNA-ribosyltransferase activity
LPV_RS10620	COG0488	(ABC) transporter
LPV_RS10625	COG3577	Aspartyl protease
LPV_RS10635	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LPV_RS10650	COG1561	YicC-like family, N-terminal region
LPV_RS10700	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
LPV_RS10710	COG0505	Belongs to the CarA family
LPV_RS10730	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
LPV_RS10740	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LPV_RS10755	COG0628	permease
LPV_RS10790	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
LPV_RS10810	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
LPV_RS10815	COG2885	chlorophyll binding
LPV_RS10820	COG3218	ABC-type transport auxiliary lipoprotein component
LPV_RS10830	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LPV_RS10835	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LPV_RS10895	COG3668	Plasmid stabilization system
LPV_RS10925	COG1278	Cold shock
LPV_RS10930	COG0513	Belongs to the DEAD box helicase family
LPV_RS10950	COG3158	transport of potassium into the cell
LPV_RS10995	COG0477	Major facilitator Superfamily
LPV_RS11005	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LPV_RS11025	COG0259	pyridoxamine-phosphate oxidase activity
LPV_RS11030	COG1733	regulation of RNA biosynthetic process
LPV_RS11035	COG1028	Short-chain dehydrogenase reductase Sdr
LPV_RS11090	COG1132	(ABC) transporter
LPV_RS11095	COG1196	nuclear chromosome segregation
LPV_RS11100	COG1196	nuclear chromosome segregation
LPV_RS11105	COG1413	lyase activity
LPV_RS11115	COG1196	nuclear chromosome segregation
LPV_RS11220	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LPV_RS11225	COG2205	protein histidine kinase activity
LPV_RS11225	COG0784	Response regulator, receiver
LPV_RS11230	COG5002	protein histidine kinase activity
LPV_RS11230	COG0784	Response regulator, receiver
LPV_RS11230	COG2198	Histidine kinase
LPV_RS11235	COG4106	trans-aconitate 2-methyltransferase activity
LPV_RS11260	COG0861	Integral membrane protein TerC family
LPV_RS11285	COG0288	reversible hydration of carbon dioxide
LPV_RS11310	COG3104	oligopeptide transport
LPV_RS11365	COG0604	alcohol dehydrogenase
LPV_RS11395	COG1090	epimerase
LPV_RS11415	COG4638	Rieske (2fe-2S)
LPV_RS11430	COG2171	N-acyltransferase activity
LPV_RS11480	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LPV_RS11485	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LPV_RS11495	COG0318	PFAM AMP-dependent synthetase and ligase
LPV_RS11505	COG1028	Short-chain dehydrogenase reductase Sdr
LPV_RS11510	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LPV_RS11515	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LPV_RS11520	COG2814	Major facilitator Superfamily
LPV_RS11535	COG1132	(ABC) transporter
LPV_RS11600	COG1301	dicarboxylic acid transport
LPV_RS11610	COG0586	Pfam SNARE associated Golgi protein
LPV_RS11620	COG0519	Catalyzes the synthesis of GMP from XMP
LPV_RS11635	COG0174	glutamine synthetase
LPV_RS11655	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
LPV_RS11670	COG2823	Periplasmic or secreted lipoprotein
LPV_RS11675	COG3243	poly(R)-hydroxyalkanoic acid synthase
LPV_RS11685	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LPV_RS11745	COG0584	glycerophosphoryl diester phosphodiesterase
LPV_RS11765	COG3185	4-Hydroxyphenylpyruvate dioxygenase
LPV_RS11775	COG0625	glutathione transferase activity
LPV_RS11795	COG1136	(ABC) transporter
LPV_RS11800	COG4591	ABC-type transport system involved in lipoprotein release permease component
LPV_RS11825	COG0546	phosphoglycolate phosphatase activity
LPV_RS11830	COG0564	pseudouridine synthase activity
LPV_RS11835	COG1530	ribonuclease E activity
LPV_RS11845	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LPV_RS11860	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LPV_RS11870	COG2890	protein-(glutamine-N5) methyltransferase activity
LPV_RS11875	COG1193	negative regulation of DNA recombination
LPV_RS11880	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LPV_RS11895	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LPV_RS11940	COG1028	Short-chain dehydrogenase reductase Sdr
LPV_RS11965	COG0814	amino acid
LPV_RS12010	COG0142	geranyltranstransferase activity
LPV_RS12015	COG2226	methyltransferase
LPV_RS12020	COG1040	competence protein
LPV_RS12045	COG2890	protein-(glutamine-N5) methyltransferase activity
LPV_RS12050	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LPV_RS12060	COG1519	Transferase
LPV_RS12065	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
LPV_RS12075	COG3240	lipase activity
LPV_RS12090	COG0513	Belongs to the DEAD box helicase family
LPV_RS12095	COG1597	lipid kinase activity
LPV_RS12100	COG0446	pyridine nucleotide-disulphide oxidoreductase
LPV_RS12100	COG1902	pentaerythritol trinitrate reductase activity
LPV_RS12105	COG2032	superoxide dismutase activity
LPV_RS12115	COG0450	alkyl hydroperoxide reductase
LPV_RS12130	COG0494	nUDIX hydrolase
LPV_RS12135	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LPV_RS12140	COG0154	amidase activity
LPV_RS12165	COG0358	DNA primase activity
LPV_RS12170	COG5433	transposase activity
LPV_RS12250	COG0582	viral genome integration into host DNA
LPV_RS12255	COG2826	transposase and inactivated derivatives, IS30 family
LPV_RS12340	COG3550	peptidyl-serine autophosphorylation
LPV_RS12345	COG3550	peptidyl-serine autophosphorylation
LPV_RS12350	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LPV_RS12435	COG0531	amino acid
LPV_RS12445	COG0477	Major facilitator Superfamily
LPV_RS12705	COG0435	Glutathione S-transferase
LPV_RS12740	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
LPV_RS12785	COG4565	transcriptional regulatory protein
LPV_RS12790	COG4251	negative regulation of phosphorylation
LPV_RS12855	COG0309	Hydrogenase expression formation protein (HypE)
LPV_RS12870	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
LPV_RS12890	COG0463	Glycosyl transferase, family 2
LPV_RS12900	COG0697	spore germination
LPV_RS12915	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LPV_RS12930	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LPV_RS12940	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LPV_RS12965	COG0517	IMP dehydrogenase activity
LPV_RS12990	COG5310	Homospermidine synthase
LPV_RS12995	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LPV_RS13025	COG0288	reversible hydration of carbon dioxide
LPV_RS13030	COG0477	Major facilitator Superfamily
LPV_RS13040	COG5433	transposase activity
LPV_RS13060	COG0784	Response regulator, receiver
LPV_RS13060	COG2205	protein histidine kinase activity
LPV_RS13070	COG1413	lyase activity
LPV_RS13075	COG1196	nuclear chromosome segregation
LPV_RS13095	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LPV_RS13115	COG1522	sequence-specific DNA binding
LPV_RS13180	COG1605	Chorismate mutase
LPV_RS13180	COG0077	Prephenate dehydratase
LPV_RS13185	COG0436	Aminotransferase
LPV_RS13195	COG1959	2 iron, 2 sulfur cluster binding
LPV_RS13260	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LPV_RS13285	COG0697	spore germination
LPV_RS13330	COG5433	transposase activity
LPV_RS13345	COG3189	MarR family transcriptional regulator
LPV_RS13365	COG1960	acyl-CoA dehydrogenase activity
LPV_RS13395	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
LPV_RS13415	COG2027	D-alanyl-D-alanine carboxypeptidase
LPV_RS13420	COG1475	DNA binding
LPV_RS13455	COG0758	DNA mediated transformation
LPV_RS13505	COG3590	peptidase
LPV_RS13515	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LPV_RS13535	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LPV_RS13545	COG0772	Belongs to the SEDS family
LPV_RS13550	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LPV_RS13555	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LPV_RS13560	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LPV_RS13565	COG3115	cell septum assembly
LPV_RS13570	COG1196	nuclear chromosome segregation
LPV_RS13595	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LPV_RS13605	COG2081	HI0933 family
LPV_RS13615	COG0795	lipopolysaccharide-transporting ATPase activity
LPV_RS13620	COG0795	lipopolysaccharide-transporting ATPase activity
LPV_RS13630	COG2927	DNA polymerase III (CHI subunit)
LPV_RS13640	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LPV_RS13675	COG1376	ErfK ybiS ycfS ynhG family protein
LPV_RS13705	COG2197	response regulator
LPV_RS13745	COG0012	GTP binding
LPV_RS13750	COG3300	MHYT domain
LPV_RS13750	COG5001	Diguanylate cyclase
LPV_RS13755	COG0142	geranyltranstransferase activity
LPV_RS13760	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
LPV_RS13770	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
LPV_RS13780	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
LPV_RS13785	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LPV_RS13795	COG0439	Biotin carboxylase
LPV_RS13815	COG2177	Part of the ABC transporter FtsEX involved in
LPV_RS13820	COG2884	Cell division ATP-binding protein ftsE
LPV_RS13825	COG0552	protein localization to endoplasmic reticulum
LPV_RS13830	COG0612	Peptidase, M16
LPV_RS13835	COG0612	Peptidase, M16
LPV_RS13840	COG0742	ribosomal rna small subunit methyltransferase
LPV_RS13860	COG0737	Belongs to the 5'-nucleotidase family
LPV_RS13860	COG1525	nuclease
LPV_RS13860	COG4085	toxin activity
LPV_RS13865	COG2226	methyltransferase
LPV_RS13870	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LPV_RS13875	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LPV_RS13875	COG1181	Belongs to the D-alanine--D-alanine ligase family
LPV_RS13890	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LPV_RS13890	COG0473	3-isopropylmalate dehydrogenase activity
LPV_RS13930	COG2608	mercury ion transmembrane transporter activity
LPV_RS13930	COG2217	Heavy metal translocating P-type atpase
LPV_RS13940	COG2226	methyltransferase
LPV_RS13950	COG0859	PFAM glycosyl transferase family 9
LPV_RS13970	COG0860	N-Acetylmuramoyl-L-alanine amidase
LPV_RS13975	COG0802	atpase or kinase
LPV_RS13980	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LPV_RS13980	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LPV_RS13985	COG2969	positive regulation of protein catabolic process
LPV_RS13990	COG0625	glutathione transferase activity
LPV_RS13995	COG2857	Cytochrome c1
LPV_RS14000	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LPV_RS14005	COG0723	plastoquinol--plastocyanin reductase activity
LPV_RS14010	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LPV_RS14025	COG0776	regulation of translation
LPV_RS14105	COG0640	Transcriptional regulator
LPV_RS14115	COG2860	membrane
LPV_RS14120	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LPV_RS14125	COG0343	queuine tRNA-ribosyltransferase activity
LPV_RS14140	COG0156	8-amino-7-oxononanoate synthase activity
LPV_RS14185	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LPV_RS14235	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LPV_RS14280	COG4536	flavin adenine dinucleotide binding
LPV_RS14285	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LPV_RS14290	COG0537	adenosine 5'-monophosphoramidase activity
LPV_RS14295	COG0302	gtp cyclohydrolase
LPV_RS14305	COG1185	polyribonucleotide nucleotidyltransferase activity
LPV_RS14330	COG2251	uridine kinase activity
LPV_RS14330	COG0195	Participates in both transcription termination and antitermination
LPV_RS14380	COG1034	ATP synthesis coupled electron transport
LPV_RS14385	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
LPV_RS14425	COG0149	triose-phosphate isomerase activity
LPV_RS14440	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LPV_RS14455	COG1534	Rna-binding protein
LPV_RS14475	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LPV_RS14490	COG3104	oligopeptide transport
LPV_RS14510	COG0308	aminopeptidase N
LPV_RS14515	COG2766	serine protein kinase
LPV_RS14525	COG2719	SpoVR family
LPV_RS14540	COG2234	aminopeptidase activity
LPV_RS14550	COG0210	DNA helicase
LPV_RS14555	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LPV_RS14570	COG0667	Aldo Keto reductase
LPV_RS14580	COG1217	gtp-binding protein TYPA
LPV_RS14590	COG0497	DNA recombination
LPV_RS14600	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
LPV_RS14600	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
LPV_RS14600	COG0666	response to abiotic stimulus
LPV_RS14600	COG0666	response to abiotic stimulus
LPV_RS14620	COG5113	peptidyl-tyrosine sulfation
LPV_RS14640	COG2183	response to ionizing radiation
LPV_RS14660	COG1054	Belongs to the UPF0176 family
LPV_RS14670	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LPV_RS14675	COG0477	Major facilitator Superfamily
LPV_RS14680	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
LPV_RS14685	COG0516	GMP reductase activity
LPV_RS14720	COG1278	Cold shock
LPV_RS14750	COG2304	oxidoreductase activity
LPV_RS14765	COG0714	Associated with various cellular activities
LPV_RS14800	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LPV_RS14825	COG0730	response to heat
LPV_RS14830	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
LPV_RS14840	COG0252	asparaginase activity
LPV_RS14850	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LPV_RS14855	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LPV_RS14865	COG0598	Magnesium transport protein CorA
LPV_RS14875	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LPV_RS14880	COG2878	Part of a membrane complex involved in electron transport
LPV_RS14890	COG0163	prenyltransferase activity
LPV_RS14910	COG0662	Cupin 2, conserved barrel domain protein
LPV_RS14910	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
LPV_RS14930	COG1192	Involved in chromosome partitioning
LPV_RS14935	COG1475	DNA binding
LPV_RS14950	COG1845	cytochrome c oxidase, subunit III
LPV_RS14955	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
LPV_RS14960	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LPV_RS14965	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LPV_RS14970	COG2010	Cytochrome c
LPV_RS15020	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LPV_RS15045	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LPV_RS15045	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LPV_RS15090	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
LPV_RS15125	COG1136	(ABC) transporter
LPV_RS15125	COG0577	efflux transmembrane transporter activity
LPV_RS15165	COG0805	protein transport
LPV_RS15180	COG0543	2 iron, 2 sulfur cluster binding
LPV_RS15180	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LPV_RS15200	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LPV_RS15240	COG1560	Kdo2-lipid A biosynthetic process
LPV_RS15260	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LPV_RS15275	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LPV_RS15310	COG0776	regulation of translation
LPV_RS15320	COG0330	HflC and HflK could
LPV_RS15365	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LPV_RS15370	COG0450	alkyl hydroperoxide reductase
LPV_RS15375	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LPV_RS15380	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LPV_RS15385	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LPV_RS15390	COG1234	tRNA 3'-trailer cleavage
LPV_RS15400	COG0281	malic enzyme
LPV_RS15405	COG0009	L-threonylcarbamoyladenylate synthase
LPV_RS15485	COG0356	it plays a direct role in the translocation of protons across the membrane
LPV_RS15500	COG2823	Periplasmic or secreted lipoprotein
LPV_RS15505	COG2823	Periplasmic or secreted lipoprotein
LPV_RS15510	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
LPV_RS15520	COG3107	peptidoglycan biosynthetic process
LPV_RS15525	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LPV_RS15555	COG0706	membrane insertase activity