locus-tag	class	description
HRS36_RS00010	COG0592	DNA-directed DNA polymerase activity
HRS36_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HRS36_RS00040	COG1166	arginine decarboxylase activity
HRS36_RS00100	COG1484	DNA-dependent DNA replication
HRS36_RS00105	COG4584	PFAM Integrase catalytic
HRS36_RS00210	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
HRS36_RS00310	COG1476	TRANSCRIPTIONal
HRS36_RS00325	COG4983	Phage plasmid primase, P4 family domain protein
HRS36_RS00350	COG4584	PFAM Integrase catalytic
HRS36_RS00360	COG1484	DNA-dependent DNA replication
HRS36_RS00380	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HRS36_RS00425	COG4644	lycopene metabolic process
HRS36_RS00430	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HRS36_RS00435	COG3012	SEC-C Motif Domain Protein
HRS36_RS00445	COG3012	SEC-C Motif Domain Protein
HRS36_RS00475	COG2963	transposase activity
HRS36_RS00500	COG4584	PFAM Integrase catalytic
HRS36_RS00505	COG1484	DNA-dependent DNA replication
HRS36_RS00520	COG3104	oligopeptide transport
HRS36_RS00525	COG1192	Involved in chromosome partitioning
HRS36_RS00530	COG1475	DNA binding
HRS36_RS00565	COG3547	Transposase (IS116 IS110 IS902 family)
HRS36_RS00580	COG4680	protein conserved in bacteria
HRS36_RS00710	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
HRS36_RS00805	COG0582	viral genome integration into host DNA
HRS36_RS00865	COG0582	viral genome integration into host DNA
HRS36_RS00890	COG0436	Aminotransferase
HRS36_RS00895	COG0556	nucleotide-excision repair
HRS36_RS00905	COG2771	luxR family
HRS36_RS00905	COG2200	EAL domain
HRS36_RS00910	COG0069	glutamate synthase activity
HRS36_RS00930	COG3079	Belongs to the UPF0149 family
HRS36_RS00935	COG0006	proline dipeptidase activity
HRS36_RS00940	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HRS36_RS00945	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HRS36_RS01000	COG0557	exoribonuclease II activity
HRS36_RS01005	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HRS36_RS01010	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HRS36_RS01045	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HRS36_RS01050	COG0784	Response regulator, receiver
HRS36_RS01050	COG2205	protein histidine kinase activity
HRS36_RS01055	COG1438	arginine binding
HRS36_RS01080	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HRS36_RS01085	COG0456	acetyltransferase
HRS36_RS01085	COG0454	-acetyltransferase
HRS36_RS01090	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HRS36_RS01095	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HRS36_RS01095	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HRS36_RS01105	COG0415	Belongs to the DNA photolyase family
HRS36_RS01110	COG2252	PERMEase
HRS36_RS01145	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HRS36_RS01175	COG1116	anion transmembrane transporter activity
HRS36_RS01180	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HRS36_RS01200	COG0656	L-ascorbic acid biosynthetic process
HRS36_RS01230	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
HRS36_RS01260	COG0469	pyruvate kinase activity
HRS36_RS01270	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HRS36_RS01275	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HRS36_RS01285	COG0339	signal peptide processing
HRS36_RS01295	COG0582	viral genome integration into host DNA
HRS36_RS01325	COG0732	type I restriction modification DNA specificity domain
HRS36_RS01350	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
HRS36_RS01360	COG3645	SOS response
HRS36_RS01365	COG0582	viral genome integration into host DNA
HRS36_RS01385	COG4983	Phage plasmid primase, P4 family domain protein
HRS36_RS01430	COG0582	viral genome integration into host DNA
HRS36_RS01485	COG1393	Belongs to the ArsC family
HRS36_RS01575	COG0306	phosphate transporter
HRS36_RS01580	COG0531	amino acid
HRS36_RS01605	COG3028	Belongs to the UPF0307 family
HRS36_RS01610	COG3240	lipase activity
HRS36_RS01620	COG3227	Zinc metalloprotease (Elastase)
HRS36_RS01630	COG1741	Belongs to the pirin family
HRS36_RS01645	COG3706	GGDEF domain
HRS36_RS01650	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HRS36_RS01690	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HRS36_RS01695	COG1509	lysine 2,3-aminomutase activity
HRS36_RS01725	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HRS36_RS01745	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
HRS36_RS01750	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HRS36_RS01805	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HRS36_RS01830	COG0222	ribosome binding
HRS36_RS02005	COG0629	single-stranded DNA binding
HRS36_RS02010	COG2814	Major facilitator Superfamily
HRS36_RS02015	COG1028	Short-chain dehydrogenase reductase Sdr
HRS36_RS02025	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HRS36_RS02030	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HRS36_RS02035	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HRS36_RS02040	COG1560	Kdo2-lipid A biosynthetic process
HRS36_RS02050	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HRS36_RS02065	COG0400	carboxylic ester hydrolase activity
HRS36_RS02090	COG0735	belongs to the Fur family
HRS36_RS02095	COG0433	COG0433 Predicted ATPase
HRS36_RS02130	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
HRS36_RS02160	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HRS36_RS02165	COG1704	LemA family
HRS36_RS02175	COG0842	Transport permease protein
HRS36_RS02180	COG1131	(ABC) transporter
HRS36_RS02185	COG1902	pentaerythritol trinitrate reductase activity
HRS36_RS02250	COG0336	Belongs to the RNA methyltransferase TrmD family
HRS36_RS02265	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HRS36_RS02280	COG0531	amino acid
HRS36_RS02315	COG1612	heme a metabolic process
HRS36_RS02350	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HRS36_RS02355	COG0363	glucosamine-6-phosphate deaminase activity
HRS36_RS02360	COG0129	dihydroxy-acid dehydratase activity
HRS36_RS02370	COG0800	Aldolase
HRS36_RS02410	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
HRS36_RS02415	COG1278	Cold shock
HRS36_RS02570	COG0439	Biotin carboxylase
HRS36_RS02575	COG0511	ligase activity, forming carbon-carbon bonds
HRS36_RS02585	COG0511	ligase activity, forming carbon-carbon bonds
HRS36_RS02585	COG5016	pyruvate
HRS36_RS02590	COG3227	Zinc metalloprotease (Elastase)
HRS36_RS02600	COG3568	Endonuclease Exonuclease Phosphatase
HRS36_RS02615	COG3588	fructose-bisphosphate aldolase
HRS36_RS02635	COG1183	phosphatidylcholine synthase activity
HRS36_RS02650	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
HRS36_RS02685	COG0330	HflC and HflK could
HRS36_RS02690	COG0330	HflC and HflK could
HRS36_RS02720	COG0793	Belongs to the peptidase S41A family
HRS36_RS02725	COG4942	peptidase
HRS36_RS02755	COG0575	Belongs to the CDS family
HRS36_RS02775	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HRS36_RS02780	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HRS36_RS02785	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HRS36_RS02815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HRS36_RS02825	COG0142	geranyltranstransferase activity
HRS36_RS02845	COG0012	GTP binding
HRS36_RS02885	COG2197	response regulator
HRS36_RS02890	COG0322	excinuclease ABC activity
HRS36_RS02915	COG0728	peptidoglycan biosynthetic process
HRS36_RS02920	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HRS36_RS02930	COG2927	DNA polymerase III (CHI subunit)
HRS36_RS02940	COG0795	lipopolysaccharide-transporting ATPase activity
HRS36_RS02945	COG0795	lipopolysaccharide-transporting ATPase activity
HRS36_RS02960	COG2081	HI0933 family
HRS36_RS02995	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HRS36_RS03005	COG0318	PFAM AMP-dependent synthetase and ligase
HRS36_RS03010	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HRS36_RS03020	COG4221	oxidoreductase activity
HRS36_RS03025	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HRS36_RS03045	COG2814	Major facilitator Superfamily
HRS36_RS03060	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HRS36_RS03105	COG1196	nuclear chromosome segregation
HRS36_RS03115	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HRS36_RS03130	COG0772	Belongs to the SEDS family
HRS36_RS03140	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HRS36_RS03150	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
HRS36_RS03160	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HRS36_RS03170	COG3590	peptidase
HRS36_RS03215	COG0758	DNA mediated transformation
HRS36_RS03225	COG0242	peptide deformylase activity
HRS36_RS03230	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HRS36_RS03285	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HRS36_RS03290	COG0583	DNA-binding transcription factor activity
HRS36_RS03295	COG1475	DNA binding
HRS36_RS03345	COG1960	acyl-CoA dehydrogenase activity
HRS36_RS03490	COG0582	viral genome integration into host DNA
HRS36_RS03500	COG4584	PFAM Integrase catalytic
HRS36_RS03505	COG1484	DNA-dependent DNA replication
HRS36_RS03575	COG1484	DNA-dependent DNA replication
HRS36_RS03580	COG4584	PFAM Integrase catalytic
HRS36_RS03600	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HRS36_RS03615	COG4372	Transposase
HRS36_RS03620	COG2267	carboxylic ester hydrolase activity
HRS36_RS03720	COG4372	Transposase
HRS36_RS03740	COG1944	ATP diphosphatase activity
HRS36_RS03745	COG4372	Transposase
HRS36_RS03790	COG0358	DNA primase activity
HRS36_RS03820	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HRS36_RS03825	COG0494	nUDIX hydrolase
HRS36_RS03855	COG2032	superoxide dismutase activity
HRS36_RS03875	COG0446	pyridine nucleotide-disulphide oxidoreductase
HRS36_RS03875	COG1902	pentaerythritol trinitrate reductase activity
HRS36_RS03895	COG3240	lipase activity
HRS36_RS03905	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
HRS36_RS03910	COG1519	Transferase
HRS36_RS03915	COG2027	D-alanyl-D-alanine carboxypeptidase
HRS36_RS03930	COG0028	Belongs to the TPP enzyme family
HRS36_RS03935	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HRS36_RS04105	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HRS36_RS04120	COG0726	polysaccharide deacetylase
HRS36_RS04130	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HRS36_RS04135	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HRS36_RS04140	COG0668	transmembrane transport
HRS36_RS04205	COG0259	pyridoxamine-phosphate oxidase activity
HRS36_RS04220	COG3240	lipase activity
HRS36_RS04225	COG0513	Belongs to the DEAD box helicase family
HRS36_RS04265	COG2217	Heavy metal translocating P-type atpase
HRS36_RS04270	COG0735	belongs to the Fur family
HRS36_RS04300	COG0513	Belongs to the DEAD box helicase family
HRS36_RS04360	COG0708	Exodeoxyribonuclease III
HRS36_RS04365	COG0708	Exodeoxyribonuclease III
HRS36_RS04375	COG0281	malic enzyme
HRS36_RS04390	COG0338	D12 class N6 adenine-specific DNA methyltransferase
HRS36_RS04400	COG0814	amino acid
HRS36_RS04405	COG0814	amino acid
HRS36_RS04460	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HRS36_RS04485	COG1272	protein, Hemolysin III
HRS36_RS04525	COG0586	Pfam SNARE associated Golgi protein
HRS36_RS04620	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
HRS36_RS04630	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
HRS36_RS04640	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HRS36_RS04650	COG2890	protein-(glutamine-N5) methyltransferase activity
HRS36_RS04660	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HRS36_RS04700	COG1960	acyl-CoA dehydrogenase activity
HRS36_RS04710	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HRS36_RS04720	COG1530	ribonuclease E activity
HRS36_RS04725	COG0564	pseudouridine synthase activity
HRS36_RS04730	COG0546	phosphoglycolate phosphatase activity
HRS36_RS04775	COG0582	viral genome integration into host DNA
HRS36_RS04815	COG1484	DNA-dependent DNA replication
HRS36_RS04820	COG4584	PFAM Integrase catalytic
HRS36_RS04945	COG1484	DNA-dependent DNA replication
HRS36_RS04950	COG4584	PFAM Integrase catalytic
HRS36_RS04970	COG0156	8-amino-7-oxononanoate synthase activity
HRS36_RS04980	COG0318	PFAM AMP-dependent synthetase and ligase
HRS36_RS04985	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HRS36_RS04995	COG0163	prenyltransferase activity
HRS36_RS05000	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HRS36_RS05040	COG0121	glutamine amidotransferase
HRS36_RS05070	COG1484	DNA-dependent DNA replication
HRS36_RS05075	COG4584	PFAM Integrase catalytic
HRS36_RS05100	COG0589	response to stress
HRS36_RS05160	COG1484	DNA-dependent DNA replication
HRS36_RS05165	COG4584	PFAM Integrase catalytic
HRS36_RS05185	COG3335	DDE superfamily endonuclease
HRS36_RS05245	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HRS36_RS05265	COG3237	CsbD-like
HRS36_RS05290	COG0644	oxidoreductase
HRS36_RS05370	COG5507	3-demethylubiquinone-9 3-methyltransferase
HRS36_RS05385	COG5599	Phosphatase
HRS36_RS05405	COG5654	RES domain protein
HRS36_RS05410	COG5642	Protein of unknown function (DUF2384)
HRS36_RS05415	COG4783	chaperone-mediated protein folding
HRS36_RS05420	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HRS36_RS05420	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HRS36_RS05425	COG0307	riboflavin synthase, alpha
HRS36_RS05430	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HRS36_RS05430	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HRS36_RS05565	COG1484	DNA-dependent DNA replication
HRS36_RS05570	COG4584	PFAM Integrase catalytic
HRS36_RS05615	COG0318	PFAM AMP-dependent synthetase and ligase
HRS36_RS05690	COG0590	tRNA wobble adenosine to inosine editing
HRS36_RS05700	COG2313	pseudouridylate synthase activity
HRS36_RS05720	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
HRS36_RS05725	COG1199	ATP-dependent helicase activity
HRS36_RS05730	COG1214	PFAM Peptidase M22, glycoprotease
HRS36_RS05745	COG0531	amino acid
HRS36_RS05755	COG4969	Belongs to the N-Me-Phe pilin family
HRS36_RS05760	COG0205	6-phosphofructokinase activity
HRS36_RS05765	COG2205	protein histidine kinase activity
HRS36_RS05765	COG5002	protein histidine kinase activity
HRS36_RS05765	COG0784	Response regulator, receiver
HRS36_RS05800	COG0625	glutathione transferase activity
HRS36_RS05810	COG3101	peptidyl-lysine hydroxylation
HRS36_RS05830	COG1484	DNA-dependent DNA replication
HRS36_RS05835	COG4584	PFAM Integrase catalytic
HRS36_RS05855	COG2850	peptidyl-arginine hydroxylation
HRS36_RS05860	COG0501	Belongs to the peptidase M48B family
HRS36_RS05875	COG3012	SEC-C Motif Domain Protein
HRS36_RS05900	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HRS36_RS05910	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HRS36_RS05930	COG2271	Major facilitator Superfamily
HRS36_RS05980	COG4584	PFAM Integrase catalytic
HRS36_RS05985	COG1484	DNA-dependent DNA replication
HRS36_RS05990	COG1090	epimerase
HRS36_RS06140	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HRS36_RS06145	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HRS36_RS06185	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HRS36_RS06190	COG0628	permease
HRS36_RS06210	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
HRS36_RS06210	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HRS36_RS06250	COG4372	Transposase
HRS36_RS06290	COG4372	Transposase
HRS36_RS06305	COG1396	sequence-specific DNA binding
HRS36_RS06315	COG4584	PFAM Integrase catalytic
HRS36_RS06320	COG1484	DNA-dependent DNA replication
HRS36_RS06335	COG4372	Transposase
HRS36_RS06360	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HRS36_RS06400	COG3706	GGDEF domain
HRS36_RS06430	COG2089	acid synthase
HRS36_RS06435	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HRS36_RS06445	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HRS36_RS06490	COG1213	nucleotidyl transferase
HRS36_RS06510	COG1083	cytidylyl-transferase
HRS36_RS06515	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
HRS36_RS06520	COG1028	Short-chain dehydrogenase reductase Sdr
HRS36_RS06535	COG0107	imidazoleglycerol-phosphate synthase activity
HRS36_RS06570	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
HRS36_RS06575	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HRS36_RS06585	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HRS36_RS06595	COG1393	Belongs to the ArsC family
HRS36_RS06620	COG0166	Belongs to the GPI family
HRS36_RS06625	COG5433	transposase activity
HRS36_RS06630	COG5433	transposase activity
HRS36_RS06640	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HRS36_RS06650	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HRS36_RS06655	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
HRS36_RS06655	COG2755	lipolytic protein G-D-S-L family
HRS36_RS06670	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HRS36_RS06680	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HRS36_RS06710	COG2226	methyltransferase
HRS36_RS06765	COG2814	Major facilitator Superfamily
HRS36_RS06775	COG1760	l-serine dehydratase
HRS36_RS06780	COG0545	Peptidyl-prolyl cis-trans isomerase
HRS36_RS06785	COG2223	nitrite transmembrane transporter activity
HRS36_RS06810	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HRS36_RS06815	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HRS36_RS06825	COG0659	secondary active sulfate transmembrane transporter activity
HRS36_RS06830	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HRS36_RS06830	COG0574	Belongs to the PEP-utilizing enzyme family
HRS36_RS06835	COG0475	glutathione-regulated potassium exporter activity
HRS36_RS06850	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HRS36_RS06855	COG1555	photosystem II stabilization
HRS36_RS06865	COG1077	Cell shape determining protein MreB Mrl
HRS36_RS06870	COG1792	Involved in formation and maintenance of cell shape
HRS36_RS06890	COG0798	PFAM Bile acid sodium symporter
HRS36_RS06915	COG3300	MHYT domain
HRS36_RS06915	COG5001	Diguanylate cyclase
HRS36_RS06930	COG0542	response to heat
HRS36_RS06990	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HRS36_RS06995	COG0352	thiamine-phosphate diphosphorylase activity
HRS36_RS07000	COG0705	Rhomboid family
HRS36_RS07025	COG1538	Outer membrane efflux protein
HRS36_RS07115	COG1137	ATPase activity
HRS36_RS07130	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HRS36_RS07140	COG1127	ABC transporter
HRS36_RS07145	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HRS36_RS07165	COG5007	Belongs to the BolA IbaG family
HRS36_RS07175	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HRS36_RS07215	COG0616	signal peptide processing
HRS36_RS07245	COG1138	Cytochrome C-type biogenesis protein
HRS36_RS07265	COG3360	Dodecin
HRS36_RS07270	COG0514	ATP-dependent DNA helicase (RecQ)
HRS36_RS07275	COG1960	acyl-CoA dehydrogenase activity
HRS36_RS07280	COG1024	Enoyl-CoA hydratase
HRS36_RS07365	COG1472	Belongs to the glycosyl hydrolase 3 family
HRS36_RS07425	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HRS36_RS07450	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HRS36_RS07455	COG1472	Belongs to the glycosyl hydrolase 3 family
HRS36_RS07465	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HRS36_RS07465	COG0140	phosphoribosyl-ATP diphosphatase activity
HRS36_RS07485	COG1280	lysine exporter protein (LysE YggA)
HRS36_RS07490	COG0456	acetyltransferase
HRS36_RS07510	COG1815	bacterial-type flagellum-dependent cell motility
HRS36_RS07515	COG1558	bacterial-type flagellum-dependent cell motility
HRS36_RS07520	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
HRS36_RS07535	COG4786	Flagellar basal body rod
HRS36_RS07550	COG1705	Flagellar rod assembly protein muramidase FlgJ
HRS36_RS07550	COG3951	Flagellar rod assembly protein muramidase FlgJ
HRS36_RS07565	COG0783	Belongs to the Dps family
HRS36_RS07595	COG1484	DNA-dependent DNA replication
HRS36_RS07605	COG4584	PFAM Integrase catalytic
HRS36_RS07610	COG4372	Transposase
HRS36_RS07645	COG0784	Response regulator, receiver
HRS36_RS07645	COG2198	Histidine kinase
HRS36_RS07645	COG2205	protein histidine kinase activity
HRS36_RS07655	COG0784	Response regulator, receiver
HRS36_RS07655	COG2198	Histidine kinase
HRS36_RS07655	COG5002	protein histidine kinase activity
HRS36_RS07685	COG3504	Conjugal transfer protein
HRS36_RS07730	COG3846	protein secretion by the type IV secretion system
HRS36_RS07840	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HRS36_RS07910	COG0477	Major facilitator Superfamily
HRS36_RS07955	COG0281	malic enzyme
HRS36_RS07980	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
HRS36_RS07985	COG0217	transcriptional regulatory protein
HRS36_RS08030	COG0642	Histidine kinase
HRS36_RS08035	COG0745	RESPONSE REGULATOR receiver
HRS36_RS08040	COG2917	probably involved in intracellular septation
HRS36_RS08045	COG1388	LysM domain
HRS36_RS08045	COG0741	lytic transglycosylase activity
HRS36_RS08055	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HRS36_RS08060	COG5310	Homospermidine synthase
HRS36_RS08065	COG1012	belongs to the aldehyde dehydrogenase family
HRS36_RS08085	COG0288	reversible hydration of carbon dioxide
HRS36_RS08115	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HRS36_RS08125	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HRS36_RS08150	COG0564	pseudouridine synthase activity
HRS36_RS08170	COG1516	flagellar protein fliS
HRS36_RS08175	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HRS36_RS08200	COG0285	dihydrofolate synthase activity
HRS36_RS08210	COG1286	toxin biosynthetic process
HRS36_RS08220	COG1466	dna polymerase III delta subunit
HRS36_RS08235	COG0815	Transfers the fatty acyl group on membrane lipoproteins
HRS36_RS08245	COG1012	belongs to the aldehyde dehydrogenase family
HRS36_RS08250	COG1024	Enoyl-CoA hydratase
HRS36_RS08250	COG1250	3-hydroxyacyl-CoA dehydrogenase
HRS36_RS08255	COG0183	Belongs to the thiolase family
HRS36_RS08280	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HRS36_RS08285	COG1732	Glycine betaine
HRS36_RS08290	COG1125	glycine betaine transport
HRS36_RS08290	COG0517	IMP dehydrogenase activity
HRS36_RS08315	COG2165	general secretion pathway protein
HRS36_RS08320	COG1459	type II secretion system
HRS36_RS08325	COG0174	glutamine synthetase
HRS36_RS08340	COG2515	1-aminocyclopropane-1-carboxylate deaminase
HRS36_RS08345	COG0326	Molecular chaperone. Has ATPase activity
HRS36_RS08370	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
HRS36_RS08380	COG0673	inositol 2-dehydrogenase activity
HRS36_RS08390	COG0772	Belongs to the SEDS family
HRS36_RS08395	COG0768	penicillin binding
HRS36_RS08435	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HRS36_RS08445	COG1376	ErfK ybiS ycfS ynhG family protein
HRS36_RS08455	COG0482	sulfurtransferase activity
HRS36_RS08485	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HRS36_RS08490	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HRS36_RS08500	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HRS36_RS08505	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HRS36_RS08510	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HRS36_RS08515	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HRS36_RS08520	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HRS36_RS08530	COG0084	hydrolase, TatD family'
HRS36_RS08535	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
HRS36_RS08565	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HRS36_RS08575	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HRS36_RS08580	COG0372	Belongs to the citrate synthase family
HRS36_RS08590	COG1073	alpha beta
HRS36_RS08605	COG0490	domain, Protein
HRS36_RS08605	COG0471	metal ion transport
HRS36_RS08620	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
HRS36_RS08625	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
HRS36_RS08630	COG0539	negative regulation of cytoplasmic translation
HRS36_RS08640	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
HRS36_RS08705	COG1028	Short-chain dehydrogenase reductase Sdr
HRS36_RS08720	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
HRS36_RS08760	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
HRS36_RS08865	COG0492	ferredoxin-NADP+ reductase activity
HRS36_RS08910	COG3138	arginine N-succinyltransferase
HRS36_RS08925	COG0281	malic enzyme
HRS36_RS08955	COG0531	amino acid
HRS36_RS08960	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HRS36_RS08965	COG3144	bacterial-type flagellum assembly
HRS36_RS08970	COG0300	oxidoreductase activity
HRS36_RS08975	COG4232	protein-disulfide reductase activity
HRS36_RS09025	COG2373	Large extracellular alpha-helical protein
HRS36_RS09030	COG4953	penicillin-binding protein 1C
HRS36_RS09080	COG2353	YceI-like domain
HRS36_RS09085	COG3038	cytochrome b561
HRS36_RS09165	COG0183	Belongs to the thiolase family
HRS36_RS09170	COG1024	Enoyl-CoA hydratase
HRS36_RS09170	COG1250	3-hydroxyacyl-CoA dehydrogenase
HRS36_RS09175	COG1376	ErfK ybiS ycfS ynhG family protein
HRS36_RS09185	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HRS36_RS09230	COG1183	phosphatidylcholine synthase activity
HRS36_RS09235	COG1012	belongs to the aldehyde dehydrogenase family
HRS36_RS09245	COG2902	Dehydrogenase
HRS36_RS09250	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HRS36_RS09285	COG2255	four-way junction helicase activity
HRS36_RS09290	COG0824	Thioesterase
HRS36_RS09305	COG3064	Membrane
HRS36_RS09330	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HRS36_RS09335	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HRS36_RS09340	COG0494	nUDIX hydrolase
HRS36_RS09345	COG0318	PFAM AMP-dependent synthetase and ligase
HRS36_RS09350	COG0850	regulation of cytokinetic process
HRS36_RS09355	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HRS36_RS09385	COG3063	Type IV pilus biogenesis stability protein PilW
HRS36_RS09425	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HRS36_RS09430	COG0617	tRNA 3'-terminal CCA addition
HRS36_RS09435	COG0861	Integral membrane protein TerC family
HRS36_RS09465	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HRS36_RS09470	COG0372	Belongs to the citrate synthase family
HRS36_RS09475	COG2079	MmgE PrpD family protein
HRS36_RS09480	COG2814	Major facilitator Superfamily
HRS36_RS09520	COG1484	DNA-dependent DNA replication
HRS36_RS09525	COG4584	PFAM Integrase catalytic
HRS36_RS09605	COG2801	Transposase and inactivated derivatives
HRS36_RS09630	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HRS36_RS09650	COG0745	RESPONSE REGULATOR receiver
HRS36_RS09665	COG1702	phosphate starvation-inducible protein PhoH
HRS36_RS09675	COG0009	L-threonylcarbamoyladenylate synthase
HRS36_RS09680	COG0180	Tryptophanyl-tRNA synthetase
HRS36_RS09685	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HRS36_RS09690	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HRS36_RS09695	COG1187	pseudouridine synthase activity
HRS36_RS09710	COG5002	protein histidine kinase activity
HRS36_RS09710	COG2198	Histidine kinase
HRS36_RS09710	COG0784	Response regulator, receiver
HRS36_RS09715	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HRS36_RS09725	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HRS36_RS09740	COG0436	Aminotransferase
HRS36_RS09750	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HRS36_RS09755	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HRS36_RS09800	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
HRS36_RS09805	COG0237	dephospho-CoA kinase activity
HRS36_RS09815	COG2200	EAL domain
HRS36_RS09830	COG0156	8-amino-7-oxononanoate synthase activity
HRS36_RS09860	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
HRS36_RS09860	COG3264	Mechanosensitive ion channel
HRS36_RS09915	COG0667	Aldo Keto reductase
HRS36_RS09975	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HRS36_RS10025	COG1484	DNA-dependent DNA replication
HRS36_RS10030	COG4584	PFAM Integrase catalytic
HRS36_RS10050	COG1286	toxin biosynthetic process
HRS36_RS10150	COG0456	acetyltransferase
HRS36_RS10155	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HRS36_RS10160	COG0508	dehydrogenase complex catalyzes the overall conversion of
HRS36_RS10180	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HRS36_RS10185	COG1686	Belongs to the peptidase S11 family
HRS36_RS10205	COG0586	Pfam SNARE associated Golgi protein
HRS36_RS10215	COG3034	peptidoglycan biosynthetic process
HRS36_RS10265	COG1278	Cold shock
HRS36_RS10275	COG0024	Methionine aminopeptidase
HRS36_RS10290	COG0519	Catalyzes the synthesis of GMP from XMP
HRS36_RS10290	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HRS36_RS10300	COG2894	cell division
HRS36_RS10350	COG1960	acyl-CoA dehydrogenase activity
HRS36_RS10355	COG2267	carboxylic ester hydrolase activity
HRS36_RS10370	COG0395	ABC-type sugar transport system, permease component
HRS36_RS10375	COG1175	transmembrane transport
HRS36_RS10385	COG0038	chloride channel
HRS36_RS10390	COG0512	Glutamine amidotransferase of anthranilate synthase
HRS36_RS10390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HRS36_RS10395	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HRS36_RS10425	COG0316	Belongs to the HesB IscA family
HRS36_RS10435	COG1104	cysteine desulfurase activity
HRS36_RS10440	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
HRS36_RS10465	COG0542	response to heat
HRS36_RS10560	COG0179	Fumarylacetoacetate (FAA) hydrolase
HRS36_RS10565	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HRS36_RS10565	COG4651	solute:proton antiporter activity
HRS36_RS10570	COG4584	PFAM Integrase catalytic
HRS36_RS10575	COG1484	DNA-dependent DNA replication
HRS36_RS10590	COG1309	transcriptional regulator
HRS36_RS10635	COG1006	Multisubunit Na H antiporter MnhC subunit
HRS36_RS10650	COG2212	antiporter activity
HRS36_RS10655	COG1320	monovalent cation:proton antiporter activity
HRS36_RS10670	COG1484	DNA-dependent DNA replication
HRS36_RS10675	COG4584	PFAM Integrase catalytic
HRS36_RS10705	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HRS36_RS10735	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HRS36_RS10745	COG1677	Flagellar hook-basal body complex protein FliE
HRS36_RS10755	COG4191	Histidine kinase
HRS36_RS10765	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HRS36_RS10775	COG1674	ftsk spoiiie
HRS36_RS10780	COG0492	ferredoxin-NADP+ reductase activity
HRS36_RS10790	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HRS36_RS10820	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
HRS36_RS10845	COG1301	dicarboxylic acid transport
HRS36_RS10855	COG0312	modulator of DNA gyrase
HRS36_RS10865	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HRS36_RS10865	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HRS36_RS10970	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HRS36_RS11005	COG1987	bacterial-type flagellum assembly
HRS36_RS11015	COG3190	flagellar
HRS36_RS11015	COG1338	Plays a role in the flagellum-specific transport system
HRS36_RS11055	COG1247	-acetyltransferase
HRS36_RS11060	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
HRS36_RS11065	COG0367	asparagine synthase
HRS36_RS11095	COG4584	PFAM Integrase catalytic
HRS36_RS11100	COG1484	DNA-dependent DNA replication
HRS36_RS11115	COG4584	PFAM Integrase catalytic
HRS36_RS11120	COG1484	DNA-dependent DNA replication
HRS36_RS11215	COG1983	PspC domain protein
HRS36_RS11220	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HRS36_RS11230	COG0196	riboflavin kinase activity
HRS36_RS11235	COG0589	response to stress
HRS36_RS11250	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HRS36_RS11295	COG0686	Belongs to the AlaDH PNT family
HRS36_RS11320	COG1994	Peptidase M50
HRS36_RS11340	COG3116	cell division
HRS36_RS11395	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HRS36_RS11435	COG1194	a g-specific adenine glycosylase
HRS36_RS11445	COG2045	Belongs to the ComB family
HRS36_RS11500	COG1294	oxidase, subunit
HRS36_RS11505	COG1271	oxidase subunit
HRS36_RS11515	COG0626	cystathionine gamma-synthase activity
HRS36_RS11520	COG0204	Acyl-transferase
HRS36_RS11535	COG1823	symporter activity
HRS36_RS11665	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HRS36_RS11690	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HRS36_RS11705	COG1484	DNA-dependent DNA replication
HRS36_RS11710	COG4584	PFAM Integrase catalytic
HRS36_RS11740	COG2996	Protein conserved in bacteria
HRS36_RS11890	COG4372	Transposase
HRS36_RS11955	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
HRS36_RS11955	COG0662	Cupin 2, conserved barrel domain protein
HRS36_RS11960	COG0297	glycogen (starch) synthase activity
HRS36_RS11965	COG4584	PFAM Integrase catalytic
HRS36_RS11985	COG1484	DNA-dependent DNA replication
HRS36_RS12000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HRS36_RS12000	COG2205	protein histidine kinase activity
HRS36_RS12090	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HRS36_RS12105	COG0629	single-stranded DNA binding
HRS36_RS12165	COG0582	viral genome integration into host DNA
HRS36_RS12195	COG4372	Transposase
HRS36_RS12215	COG0833	amino acid
HRS36_RS12220	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HRS36_RS12240	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
HRS36_RS12255	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HRS36_RS12260	COG0601	transmembrane transport
HRS36_RS12270	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HRS36_RS12290	COG0531	amino acid
HRS36_RS12295	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HRS36_RS12300	COG0318	PFAM AMP-dependent synthetase and ligase
HRS36_RS12320	COG4372	Transposase
HRS36_RS12330	COG0312	modulator of DNA gyrase
HRS36_RS12340	COG0670	Belongs to the BI1 family
HRS36_RS12400	COG0113	porphobilinogen synthase activity
HRS36_RS12415	COG0527	aspartate kinase activity
HRS36_RS12480	COG1960	acyl-CoA dehydrogenase activity
HRS36_RS12485	COG0183	Belongs to the thiolase family
HRS36_RS12495	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HRS36_RS12515	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HRS36_RS12525	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HRS36_RS12530	COG2011	ABC-type metal ion transport system permease component
HRS36_RS12535	COG1464	Belongs to the NlpA lipoprotein family
HRS36_RS12555	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HRS36_RS12560	COG0751	glycine-tRNA ligase activity
HRS36_RS12575	COG0210	DNA helicase
HRS36_RS12600	COG0028	Belongs to the TPP enzyme family
HRS36_RS12610	COG2853	Lipoprotein
HRS36_RS12640	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HRS36_RS12650	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
HRS36_RS12670	COG0572	uridine kinase
HRS36_RS12700	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HRS36_RS12800	COG0681	Belongs to the peptidase S26 family
HRS36_RS12810	COG2951	lytic endotransglycosylase activity
HRS36_RS12820	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
HRS36_RS12830	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
HRS36_RS12860	COG0232	Belongs to the dGTPase family. Type 2 subfamily
HRS36_RS12865	COG5433	transposase activity
HRS36_RS12895	COG0519	Catalyzes the synthesis of GMP from XMP
HRS36_RS12925	COG1028	Short-chain dehydrogenase reductase Sdr
HRS36_RS12965	COG1011	Hydrolase
HRS36_RS13030	COG5433	transposase activity
HRS36_RS13050	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
HRS36_RS13060	COG1484	DNA-dependent DNA replication
HRS36_RS13065	COG4584	PFAM Integrase catalytic
HRS36_RS13090	COG4372	Transposase
HRS36_RS13110	COG1301	dicarboxylic acid transport
HRS36_RS13145	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
HRS36_RS13200	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HRS36_RS13205	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HRS36_RS13210	COG1862	Preprotein translocase
HRS36_RS13240	COG3577	Aspartyl protease
HRS36_RS13250	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HRS36_RS13265	COG1561	YicC-like family, N-terminal region
HRS36_RS13315	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
HRS36_RS13325	COG0505	Belongs to the CarA family
HRS36_RS13345	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
HRS36_RS13350	COG0429	hydrolase of the alpha beta-hydrolase fold
HRS36_RS13380	COG0628	permease
HRS36_RS13450	COG0148	phosphopyruvate hydratase activity
HRS36_RS13455	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
HRS36_RS13475	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
HRS36_RS13480	COG2885	chlorophyll binding
HRS36_RS13485	COG3218	ABC-type transport auxiliary lipoprotein component
HRS36_RS13495	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HRS36_RS13500	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HRS36_RS13585	COG4372	Transposase
HRS36_RS13610	COG4372	Transposase
HRS36_RS13650	COG4372	Transposase
HRS36_RS13680	COG1396	sequence-specific DNA binding
HRS36_RS13690	COG0456	acetyltransferase
HRS36_RS13690	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HRS36_RS13695	COG1484	DNA-dependent DNA replication
HRS36_RS13700	COG4584	PFAM Integrase catalytic
HRS36_RS13735	COG0454	-acetyltransferase
HRS36_RS13765	COG1297	OPT oligopeptide transporter protein
HRS36_RS13780	COG1028	Short-chain dehydrogenase reductase Sdr
HRS36_RS13805	COG0488	(ABC) transporter
HRS36_RS13815	COG0156	8-amino-7-oxononanoate synthase activity
HRS36_RS13820	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HRS36_RS13825	COG1538	Outer membrane efflux protein
HRS36_RS13840	COG0659	secondary active sulfate transmembrane transporter activity
HRS36_RS13865	COG1250	3-hydroxyacyl-CoA dehydrogenase
HRS36_RS13875	COG0583	DNA-binding transcription factor activity
HRS36_RS13895	COG0187	DNA topoisomerase II activity
HRS36_RS13900	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HRS36_RS13940	COG4232	protein-disulfide reductase activity
HRS36_RS13955	COG0471	metal ion transport
HRS36_RS13955	COG3273	potassium ion transport
HRS36_RS13970	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HRS36_RS13975	COG0741	lytic transglycosylase activity
HRS36_RS13980	COG1653	transport
HRS36_RS13985	COG0584	glycerophosphoryl diester phosphodiesterase
HRS36_RS13995	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HRS36_RS14015	COG0625	glutathione transferase activity
HRS36_RS14045	COG4591	ABC-type transport system involved in lipoprotein release permease component
HRS36_RS14080	COG5433	transposase activity
HRS36_RS14100	COG1253	flavin adenine dinucleotide binding
HRS36_RS14125	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HRS36_RS14145	COG4372	Transposase
HRS36_RS14175	COG3335	DDE superfamily endonuclease
HRS36_RS14200	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HRS36_RS14230	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HRS36_RS14285	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
HRS36_RS14290	COG3046	protein related to deoxyribodipyrimidine photolyase
HRS36_RS14295	COG2963	transposase activity
HRS36_RS14330	COG1028	Short-chain dehydrogenase reductase Sdr
HRS36_RS14340	COG4689	acetoacetate decarboxylase
HRS36_RS14365	COG0814	amino acid
HRS36_RS14410	COG0142	geranyltranstransferase activity
HRS36_RS14415	COG2226	methyltransferase
HRS36_RS14420	COG1040	competence protein
HRS36_RS14455	COG2890	protein-(glutamine-N5) methyltransferase activity
HRS36_RS14460	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HRS36_RS14475	COG4372	Transposase
HRS36_RS14480	COG4372	Transposase
HRS36_RS14545	COG4935	Belongs to the peptidase S8 family
HRS36_RS14545	COG2234	aminopeptidase activity
HRS36_RS14590	COG1090	epimerase
HRS36_RS14600	COG0589	response to stress
HRS36_RS14655	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HRS36_RS14665	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HRS36_RS14685	COG1560	Kdo2-lipid A biosynthetic process
HRS36_RS14710	COG0477	Major facilitator Superfamily
HRS36_RS14780	COG1484	DNA-dependent DNA replication
HRS36_RS14790	COG4584	PFAM Integrase catalytic
HRS36_RS14800	COG2271	Major facilitator Superfamily
HRS36_RS14805	COG1522	sequence-specific DNA binding
HRS36_RS14845	COG0463	Glycosyl transferase, family 2
HRS36_RS14880	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HRS36_RS14890	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HRS36_RS14895	COG0756	dUTP diphosphatase activity
HRS36_RS14900	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HRS36_RS14905	COG2003	Belongs to the UPF0758 family
HRS36_RS14920	COG2194	sulfuric ester hydrolase activity
HRS36_RS14940	COG0288	reversible hydration of carbon dioxide
HRS36_RS14955	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HRS36_RS14960	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HRS36_RS14965	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HRS36_RS14970	COG1028	Short-chain dehydrogenase reductase Sdr
HRS36_RS14975	COG1024	Enoyl-CoA hydratase
HRS36_RS14980	COG1028	Short-chain dehydrogenase reductase Sdr
HRS36_RS14990	COG3425	synthase
HRS36_RS14995	COG0457	Tetratricopeptide repeat
HRS36_RS14995	COG3118	belongs to the thioredoxin family
HRS36_RS15005	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HRS36_RS15020	COG1215	transferase activity, transferring glycosyl groups
HRS36_RS15030	COG1215	transferase activity, transferring glycosyl groups
HRS36_RS15035	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
HRS36_RS15060	COG2151	metal-sulfur cluster biosynthetic enzyme
HRS36_RS15070	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HRS36_RS15075	COG0719	Fe-S assembly protein
HRS36_RS15080	COG0396	ATPase activity
HRS36_RS15085	COG0719	Fe-S assembly protein
HRS36_RS15095	COG3243	poly(R)-hydroxyalkanoic acid synthase
HRS36_RS15105	COG0398	Pfam SNARE associated Golgi protein
HRS36_RS15120	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HRS36_RS15125	COG0347	Belongs to the P(II) protein family
HRS36_RS15135	COG0606	chelatase, subunit chli
HRS36_RS15150	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HRS36_RS15165	COG1392	Phosphate transport regulator
HRS36_RS15170	COG0306	phosphate transporter
HRS36_RS15180	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HRS36_RS15185	COG0842	Transport permease protein
HRS36_RS15190	COG1131	(ABC) transporter
HRS36_RS15195	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HRS36_RS15200	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HRS36_RS15205	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HRS36_RS15235	COG0739	heme binding
HRS36_RS15240	COG0700	Nucleoside recognition
HRS36_RS15265	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
HRS36_RS15270	COG1028	Short-chain dehydrogenase reductase Sdr
HRS36_RS15275	COG1028	Short-chain dehydrogenase reductase Sdr
HRS36_RS15295	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HRS36_RS15320	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
HRS36_RS15330	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HRS36_RS15365	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
HRS36_RS15375	COG2814	Major facilitator Superfamily
HRS36_RS15405	COG0508	dehydrogenase complex catalyzes the overall conversion of
HRS36_RS15410	COG0567	Dehydrogenase, E1 component
HRS36_RS15415	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HRS36_RS15425	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
HRS36_RS15430	COG2009	succinate dehydrogenase
HRS36_RS15475	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HRS36_RS15535	COG0439	Biotin carboxylase
HRS36_RS15555	COG2177	Part of the ABC transporter FtsEX involved in
HRS36_RS15560	COG2884	Cell division ATP-binding protein ftsE
HRS36_RS15565	COG0552	protein localization to endoplasmic reticulum
HRS36_RS15570	COG0612	Peptidase, M16
HRS36_RS15575	COG0612	Peptidase, M16
HRS36_RS15580	COG0742	ribosomal rna small subunit methyltransferase
HRS36_RS15600	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HRS36_RS15600	COG1181	Belongs to the D-alanine--D-alanine ligase family
HRS36_RS15605	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HRS36_RS15615	COG0473	3-isopropylmalate dehydrogenase activity
HRS36_RS15615	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HRS36_RS15655	COG2217	Heavy metal translocating P-type atpase
HRS36_RS15675	COG0424	maF-like protein
HRS36_RS15710	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HRS36_RS15735	COG0859	PFAM glycosyl transferase family 9
HRS36_RS15750	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HRS36_RS15755	COG0860	N-Acetylmuramoyl-L-alanine amidase
HRS36_RS15760	COG0802	atpase or kinase
HRS36_RS15765	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HRS36_RS15765	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HRS36_RS15770	COG2969	positive regulation of protein catabolic process
HRS36_RS15775	COG0625	glutathione transferase activity
HRS36_RS15785	COG2857	Cytochrome c1
HRS36_RS15790	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HRS36_RS15795	COG0723	plastoquinol--plastocyanin reductase activity
HRS36_RS15805	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
HRS36_RS15820	COG0776	regulation of translation
HRS36_RS15825	COG0072	phenylalanine-tRNA ligase activity
HRS36_RS15825	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HRS36_RS15875	COG0477	Major facilitator Superfamily
HRS36_RS15885	COG2860	membrane
HRS36_RS15890	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HRS36_RS15895	COG0343	queuine tRNA-ribosyltransferase activity
HRS36_RS15940	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HRS36_RS15950	COG0617	tRNA 3'-terminal CCA addition
HRS36_RS15955	COG1162	GTPase activity
HRS36_RS15995	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HRS36_RS16050	COG0154	amidase activity
HRS36_RS16055	COG2066	Belongs to the glutaminase family
HRS36_RS16100	COG1028	Short-chain dehydrogenase reductase Sdr
HRS36_RS16100	COG4221	oxidoreductase activity
HRS36_RS16100	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HRS36_RS16100	COG3321	synthase
HRS36_RS16130	COG1484	DNA-dependent DNA replication
HRS36_RS16135	COG4584	PFAM Integrase catalytic
HRS36_RS16140	COG2801	Transposase and inactivated derivatives
HRS36_RS16190	COG5001	Diguanylate cyclase
HRS36_RS16190	COG4251	negative regulation of phosphorylation
HRS36_RS16190	COG3706	GGDEF domain
HRS36_RS16190	COG2203	Gaf domain
HRS36_RS16205	COG4181	ATPase activity
HRS36_RS16210	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
HRS36_RS16240	COG0435	Glutathione S-transferase
HRS36_RS16245	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HRS36_RS16265	COG4536	flavin adenine dinucleotide binding
HRS36_RS16270	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HRS36_RS16275	COG0537	adenosine 5'-monophosphoramidase activity
HRS36_RS16280	COG0302	gtp cyclohydrolase
HRS36_RS16310	COG2251	uridine kinase activity
HRS36_RS16310	COG0195	Participates in both transcription termination and antitermination
HRS36_RS16345	COG0839	Belongs to the complex I subunit 6 family
HRS36_RS16355	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
HRS36_RS16360	COG1034	ATP synthesis coupled electron transport
HRS36_RS16365	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HRS36_RS16380	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HRS36_RS16420	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HRS36_RS16435	COG1534	Rna-binding protein
HRS36_RS16465	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HRS36_RS16500	COG0024	Methionine aminopeptidase
HRS36_RS16505	COG3104	oligopeptide transport
HRS36_RS16535	COG0308	aminopeptidase N
HRS36_RS16540	COG2766	serine protein kinase
HRS36_RS16550	COG2719	SpoVR family
HRS36_RS16570	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HRS36_RS16570	COG2070	2-Nitropropane dioxygenase
HRS36_RS16575	COG0210	DNA helicase
HRS36_RS16590	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HRS36_RS16595	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HRS36_RS16615	COG0497	DNA recombination
HRS36_RS16625	COG0431	NADPH-dependent FMN reductase
HRS36_RS16630	COG4804	nuclease activity
HRS36_RS16640	COG4974	Belongs to the 'phage' integrase family
HRS36_RS16675	COG1506	peptidase
HRS36_RS16675	COG4946	Tricorn protease homolog
HRS36_RS16675	COG0823	Involved in the tonB-independent uptake of proteins
HRS36_RS16680	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HRS36_RS16685	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HRS36_RS16705	COG2183	response to ionizing radiation
HRS36_RS16735	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HRS36_RS16750	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
HRS36_RS16755	COG0516	GMP reductase activity
HRS36_RS16780	COG3719	Belongs to the RNase T2 family
HRS36_RS16815	COG2304	oxidoreductase activity
HRS36_RS16830	COG0714	Associated with various cellular activities
HRS36_RS16840	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HRS36_RS16865	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HRS36_RS16885	COG2801	Transposase and inactivated derivatives
HRS36_RS16895	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HRS36_RS16900	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HRS36_RS16905	COG0730	response to heat
HRS36_RS16910	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
HRS36_RS16925	COG0252	asparaginase activity
HRS36_RS16950	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HRS36_RS16955	COG2878	Part of a membrane complex involved in electron transport
HRS36_RS16980	COG0662	Cupin 2, conserved barrel domain protein
HRS36_RS16980	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
HRS36_RS17000	COG0357	Ribosomal RNA small subunit methyltransferase G
HRS36_RS17005	COG1192	Involved in chromosome partitioning
HRS36_RS17010	COG1475	DNA binding
HRS36_RS17025	COG1845	cytochrome c oxidase, subunit III
HRS36_RS17035	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HRS36_RS17040	COG1565	acr, cog1565
HRS36_RS17040	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HRS36_RS17045	COG2010	Cytochrome c
HRS36_RS17095	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
HRS36_RS17105	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HRS36_RS17115	COG1064	alcohol dehydrogenase
HRS36_RS17130	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HRS36_RS17130	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HRS36_RS17155	COG1136	(ABC) transporter
HRS36_RS17155	COG0577	efflux transmembrane transporter activity
HRS36_RS17160	COG1136	(ABC) transporter
HRS36_RS17175	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HRS36_RS17230	COG0805	protein transport
HRS36_RS17250	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HRS36_RS17250	COG0543	2 iron, 2 sulfur cluster binding
HRS36_RS17260	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HRS36_RS17270	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HRS36_RS17275	COG0114	fumarate hydratase activity
HRS36_RS17290	COG1216	Glycosyl transferase, family 2
HRS36_RS17355	COG0776	regulation of translation
HRS36_RS17365	COG0330	HflC and HflK could
HRS36_RS17395	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HRS36_RS17420	COG0418	dihydroorotase activity
HRS36_RS17425	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HRS36_RS17430	COG0450	alkyl hydroperoxide reductase
HRS36_RS17435	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HRS36_RS17440	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HRS36_RS17445	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HRS36_RS17450	COG0584	glycerophosphoryl diester phosphodiesterase
HRS36_RS17455	COG0009	L-threonylcarbamoyladenylate synthase
HRS36_RS17465	COG0688	phosphatidylethanolamine metabolic process
HRS36_RS17485	COG4974	Belongs to the 'phage' integrase family
HRS36_RS17540	COG0356	it plays a direct role in the translocation of protons across the membrane
HRS36_RS17560	COG2823	Periplasmic or secreted lipoprotein
HRS36_RS17565	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
HRS36_RS17580	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HRS36_RS17595	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HRS36_RS17600	COG0706	membrane insertase activity
HRS36_RS17630	COG0489	protein tyrosine kinase activity
HRS36_RS17645	COG4644	lycopene metabolic process
HRS36_RS17650	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HRS36_RS17655	COG3012	SEC-C Motif Domain Protein
HRS36_RS17665	COG3012	SEC-C Motif Domain Protein
HRS36_RS17685	COG4974	Belongs to the 'phage' integrase family
HRS36_RS17690	COG4644	lycopene metabolic process
HRS36_RS17710	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HRS36_RS17730	COG1484	DNA-dependent DNA replication
HRS36_RS17735	COG4584	PFAM Integrase catalytic
HRS36_RS17740	COG4584	PFAM Integrase catalytic
HRS36_RS17745	COG1484	DNA-dependent DNA replication
HRS36_RS17760	COG4644	lycopene metabolic process
HRS36_RS17765	COG4974	Belongs to the 'phage' integrase family
HRS36_RS17785	COG3077	Addiction module antitoxin, RelB DinJ family
HRS36_RS17830	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HRS36_RS17850	COG2176	DNA-directed DNA polymerase activity
HRS36_RS17875	COG4974	Belongs to the 'phage' integrase family
HRS36_RS17880	COG4974	Belongs to the 'phage' integrase family
HRS36_RS17900	COG4584	PFAM Integrase catalytic
HRS36_RS17905	COG1484	DNA-dependent DNA replication
HRS36_RS17935	COG0484	heat shock protein binding
HRS36_RS17975	COG1872	DUF167
HRS36_RS18115	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HRS36_RS18140	COG1475	DNA binding
HRS36_RS18155	COG2198	Histidine kinase
HRS36_RS18155	COG0784	Response regulator, receiver
HRS36_RS18155	COG5002	protein histidine kinase activity
HRS36_RS18225	COG4372	Transposase
HRS36_RS18240	COG3012	SEC-C Motif Domain Protein
HRS36_RS18250	COG3012	SEC-C Motif Domain Protein
HRS36_RS18255	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HRS36_RS18260	COG4644	lycopene metabolic process
HRS36_RS18270	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HRS36_RS18280	COG0629	single-stranded DNA binding
HRS36_RS18295	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HRS36_RS18320	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HRS36_RS18350	COG0784	Response regulator, receiver
HRS36_RS18350	COG2198	Histidine kinase
HRS36_RS18350	COG2205	protein histidine kinase activity
HRS36_RS18375	COG0517	IMP dehydrogenase activity
HRS36_RS18380	COG4974	Belongs to the 'phage' integrase family
HRS36_RS18410	COG0653	protein targeting
HRS36_RS18425	COG4584	PFAM Integrase catalytic
HRS36_RS18430	COG1484	DNA-dependent DNA replication
HRS36_RS18460	COG4974	Belongs to the 'phage' integrase family
HRS36_RS18470	COG1484	DNA-dependent DNA replication
HRS36_RS18475	COG4584	PFAM Integrase catalytic
HRS36_RS18480	COG4974	Belongs to the 'phage' integrase family
HRS36_RS18485	COG4644	lycopene metabolic process