locus-tag	class	description
O159_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
O159_RS00010	COG0592	DNA-directed DNA polymerase activity
O159_RS00015	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
O159_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
O159_RS00025	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
O159_RS00030	COG0187	DNA topoisomerase II activity
O159_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
O159_RS00075	COG0494	nUDIX hydrolase
O159_RS00090	COG0705	Rhomboid family
O159_RS00105	COG3764	Sortase (surface protein transpeptidase)
O159_RS00125	COG0515	serine threonine protein kinase
O159_RS00130	COG0768	penicillin binding
O159_RS00145	COG1716	ATPase activity
O159_RS00170	COG1649	PFAM Uncharacterised BCR, COG1649
O159_RS00195	COG4214	carbohydrate transport
O159_RS00200	COG4213	ABC transporter substrate-binding protein
O159_RS00230	COG1846	Transcriptional regulator
O159_RS00230	COG1940	carbohydrate kinase activity
O159_RS00270	COG1959	2 iron, 2 sulfur cluster binding
O159_RS00270	COG1295	ribonuclease BN
O159_RS00290	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
O159_RS00295	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
O159_RS00315	COG1755	Isoprenylcysteine carboxyl methyltransferase
O159_RS00340	COG1414	Transcriptional regulator
O159_RS00360	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
O159_RS00365	COG2610	gluconate transmembrane transporter activity
O159_RS00370	COG0246	Mannitol dehydrogenase
O159_RS00375	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
O159_RS00385	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
O159_RS00405	COG3711	transcriptional antiterminator
O159_RS00405	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
O159_RS00420	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
O159_RS00425	COG2706	6-phosphogluconolactonase activity
O159_RS00455	COG0534	Mate efflux family protein
O159_RS00480	COG3590	peptidase
O159_RS00490	COG0019	diaminopimelate decarboxylase activity
O159_RS00500	COG2826	transposase and inactivated derivatives, IS30 family
O159_RS00510	COG0423	glycine-tRNA ligase activity
O159_RS00515	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
O159_RS00520	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
O159_RS00525	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
O159_RS00545	COG3253	May function as heme-dependent peroxidase
O159_RS00550	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
O159_RS00555	COG0181	hydroxymethylbilane synthase activity
O159_RS00565	COG0113	porphobilinogen synthase activity
O159_RS00570	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
O159_RS00615	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
O159_RS00640	COG0531	amino acid
O159_RS00665	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
O159_RS00730	COG0656	L-ascorbic acid biosynthetic process
O159_RS00805	COG2957	Belongs to the agmatine deiminase family
O159_RS00815	COG0137	argininosuccinate synthase activity
O159_RS00835	COG0577	efflux transmembrane transporter activity
O159_RS00835	COG1136	(ABC) transporter
O159_RS00855	COG0513	Belongs to the DEAD box helicase family
O159_RS00900	COG1129	ABC transporter
O159_RS00910	COG0745	RESPONSE REGULATOR receiver
O159_RS00940	COG0569	domain protein
O159_RS00945	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
O159_RS00950	COG0640	Transcriptional regulator
O159_RS00975	COG1802	Transcriptional regulator
O159_RS00995	COG2226	methyltransferase
O159_RS01000	COG0142	geranyltranstransferase activity
O159_RS01015	COG2755	lipolytic protein G-D-S-L family
O159_RS01015	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
O159_RS01030	COG1666	GTP binding
O159_RS01055	COG0739	heme binding
O159_RS01060	COG0366	Alpha amylase catalytic
O159_RS01125	COG0025	NhaP-type Na H and K H
O159_RS01135	COG2030	dehydratase
O159_RS01145	COG0812	UDP-N-acetylmuramate dehydrogenase activity
O159_RS01150	COG3415	Transposase
O159_RS01150	COG2801	Transposase and inactivated derivatives
O159_RS01210	COG0081	regulation of translation
O159_RS01215	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
O159_RS01225	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
O159_RS01235	COG0514	ATP-dependent DNA helicase (RecQ)
O159_RS01300	COG2826	transposase and inactivated derivatives, IS30 family
O159_RS01390	COG1203	CRISPR-associated helicase, Cas3
O159_RS01420	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
O159_RS01430	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
O159_RS01445	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
O159_RS01455	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
O159_RS01460	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
O159_RS01485	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
O159_RS01490	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
O159_RS01500	COG0302	gtp cyclohydrolase
O159_RS01505	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
O159_RS01520	COG0037	tRNA processing
O159_RS01525	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
O159_RS01535	COG0741	lytic transglycosylase activity
O159_RS01535	COG1196	nuclear chromosome segregation
O159_RS01535	COG0739	heme binding
O159_RS01560	COG2847	Copper chaperone PCu(A)C
O159_RS01615	COG1122	ATPase activity
O159_RS01620	COG0183	Belongs to the thiolase family
O159_RS01630	COG1268	BioY protein
O159_RS01645	COG1316	TRANSCRIPTIONal
O159_RS01650	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
O159_RS01655	COG1201	RNA secondary structure unwinding
O159_RS01690	COG1673	EVE domain
O159_RS01735	COG0085	RNA polymerase activity
O159_RS01740	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
O159_RS01755	COG0257	Belongs to the bacterial ribosomal protein bL36 family
O159_RS01790	COG0803	Belongs to the bacterial solute-binding protein 9 family
O159_RS01800	COG1108	ABC-type Mn2 Zn2 transport systems permease components
O159_RS01820	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
O159_RS01825	COG0049	tRNA binding
O159_RS01830	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
O159_RS01835	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
O159_RS01850	COG1215	transferase activity, transferring glycosyl groups
O159_RS01865	COG2027	D-alanyl-D-alanine carboxypeptidase
O159_RS01870	COG2409	Drug exporters of the RND superfamily
O159_RS01905	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
O159_RS01910	COG1132	(ABC) transporter
O159_RS01915	COG0477	Major facilitator Superfamily
O159_RS01930	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
O159_RS01935	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
O159_RS01935	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
O159_RS01965	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
O159_RS01970	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
O159_RS01975	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
O159_RS01985	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
O159_RS01990	COG0180	Tryptophanyl-tRNA synthetase
O159_RS01995	COG0708	Exodeoxyribonuclease III
O159_RS02025	COG2009	succinate dehydrogenase
O159_RS02040	COG0438	transferase activity, transferring glycosyl groups
O159_RS02045	COG0598	Magnesium transport protein CorA
O159_RS02055	COG3845	ABC transporter
O159_RS02060	COG4603	Belongs to the binding-protein-dependent transport system permease family
O159_RS02065	COG1079	Belongs to the binding-protein-dependent transport system permease family
O159_RS02080	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
O159_RS02085	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
O159_RS02095	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
O159_RS02110	COG0025	NhaP-type Na H and K H
O159_RS02120	COG4770	biotin carboxylase activity
O159_RS02125	COG0424	maF-like protein
O159_RS02130	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
O159_RS02175	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
O159_RS02200	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
O159_RS02205	COG1316	TRANSCRIPTIONal
O159_RS02230	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
O159_RS02255	COG1215	transferase activity, transferring glycosyl groups
O159_RS02265	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
O159_RS02315	COG1086	Polysaccharide biosynthesis protein
O159_RS02325	COG0438	transferase activity, transferring glycosyl groups
O159_RS02345	COG1216	Glycosyl transferase, family 2
O159_RS02370	COG1072	(Pantothenic acid kinase))
O159_RS02375	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
O159_RS02380	COG0736	holo-[acyl-carrier-protein] synthase activity
O159_RS02385	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
O159_RS02390	COG0802	atpase or kinase
O159_RS02405	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
O159_RS02420	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
O159_RS02435	COG0516	GMP reductase activity
O159_RS02440	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
O159_RS02465	COG0519	Catalyzes the synthesis of GMP from XMP
O159_RS02465	COG0518	GMP synthase (glutamine-hydrolyzing) activity
O159_RS02480	COG0584	glycerophosphoryl diester phosphodiesterase
O159_RS02500	COG0045	succinate-CoA ligase (ADP-forming) activity
O159_RS02530	COG0138	bifunctional purine biosynthesis protein purh
O159_RS02535	COG1834	amidinotransferase
O159_RS02550	COG2201	protein-glutamate methylesterase activity
O159_RS02555	COG2197	response regulator
O159_RS02560	COG4585	Histidine kinase
O159_RS02640	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
O159_RS02655	COG1105	Belongs to the carbohydrate kinase PfkB family
O159_RS02660	COG1940	carbohydrate kinase activity
O159_RS02665	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
O159_RS02710	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
O159_RS02725	COG2755	lipolytic protein G-D-S-L family
O159_RS02725	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
O159_RS02760	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
O159_RS02765	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
O159_RS02800	COG1349	DNA-binding transcription factor activity
O159_RS02815	COG1482	cell wall glycoprotein biosynthetic process
O159_RS02820	COG1960	acyl-CoA dehydrogenase activity
O159_RS02825	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
O159_RS02850	COG0745	RESPONSE REGULATOR receiver
O159_RS02865	COG4044	May play a role in the intracellular transport of hydrophobic ligands
O159_RS02870	COG0354	folic acid binding
O159_RS02880	COG0588	phosphoglycerate mutase activity
O159_RS02890	COG5002	protein histidine kinase activity
O159_RS02895	COG0745	RESPONSE REGULATOR receiver
O159_RS02905	COG1329	Transcriptional regulator
O159_RS02910	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
O159_RS02910	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
O159_RS02915	COG0215	cysteine-tRNA ligase activity
O159_RS02920	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
O159_RS02930	COG2197	response regulator
O159_RS02945	COG3842	ATPase activity
O159_RS02965	COG2851	Citrate transporter
O159_RS02970	COG3290	protein histidine kinase activity
O159_RS02975	COG4565	transcriptional regulatory protein
O159_RS02980	COG3795	YCII-related domain
O159_RS03005	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
O159_RS03020	COG1278	Cold shock
O159_RS03025	COG0459	protein refolding
O159_RS03035	COG2205	protein histidine kinase activity
O159_RS03040	COG0745	RESPONSE REGULATOR receiver
O159_RS03045	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
O159_RS03070	COG1278	Cold shock
O159_RS03085	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
O159_RS03130	COG2801	Transposase and inactivated derivatives
O159_RS03130	COG3415	Transposase
O159_RS03155	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
O159_RS03180	COG2986	histidine ammonia-lyase
O159_RS03200	COG1126	abc transporter atp-binding protein
O159_RS03205	COG1942	4-Oxalocrotonate Tautomerase
O159_RS03210	COG1643	Atp-dependent helicase
O159_RS03230	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
O159_RS03235	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
O159_RS03250	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
O159_RS03255	COG0488	(ABC) transporter
O159_RS03265	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
O159_RS03270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
O159_RS03275	COG0084	hydrolase, TatD family'
O159_RS03280	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
O159_RS03300	COG0386	Belongs to the glutathione peroxidase family
O159_RS03305	COG1737	Transcriptional regulator
O159_RS03310	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
O159_RS03320	COG0277	FAD linked oxidase domain protein
O159_RS03335	COG1760	l-serine dehydratase
O159_RS03400	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
O159_RS03405	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
O159_RS03425	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
O159_RS03470	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
O159_RS03485	COG0196	riboflavin kinase activity
O159_RS03500	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
O159_RS03505	COG1012	belongs to the aldehyde dehydrogenase family
O159_RS03510	COG1012	belongs to the aldehyde dehydrogenase family
O159_RS03525	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
O159_RS03535	COG0748	coenzyme F420 binding
O159_RS03545	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
O159_RS03550	COG1937	Protein conserved in bacteria
O159_RS03575	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
O159_RS03585	COG2197	response regulator
O159_RS03590	COG4585	Histidine kinase
O159_RS03630	COG2826	transposase and inactivated derivatives, IS30 family
O159_RS03660	COG4974	Belongs to the 'phage' integrase family
O159_RS03685	COG2252	PERMEase
O159_RS03690	COG0220	tRNA (guanine-N7-)-methyltransferase activity
O159_RS03710	COG0277	FAD linked oxidase domain protein
O159_RS03715	COG0545	Peptidyl-prolyl cis-trans isomerase
O159_RS03730	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
O159_RS03780	COG4974	Belongs to the 'phage' integrase family
O159_RS03785	COG2826	transposase and inactivated derivatives, IS30 family
O159_RS03800	COG1704	LemA family
O159_RS03810	COG1185	polyribonucleotide nucleotidyltransferase activity
O159_RS03815	COG2171	N-acyltransferase activity
O159_RS03820	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
O159_RS03865	COG2239	Acts as a magnesium transporter
O159_RS03875	COG0006	proline dipeptidase activity
O159_RS03890	COG0513	Belongs to the DEAD box helicase family
O159_RS03935	COG1733	regulation of RNA biosynthetic process
O159_RS03960	COG3480	Lon protease (S16) C-terminal proteolytic domain
O159_RS03965	COG1615	UPF0182 protein
O159_RS03985	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
O159_RS03990	COG0745	RESPONSE REGULATOR receiver
O159_RS04000	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
O159_RS04020	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
O159_RS04050	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
O159_RS04055	COG1131	(ABC) transporter
O159_RS04070	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
O159_RS04075	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
O159_RS04080	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
O159_RS04085	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
O159_RS04090	COG0586	Pfam SNARE associated Golgi protein
O159_RS04100	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
O159_RS04105	COG2884	Cell division ATP-binding protein ftsE
O159_RS04110	COG2177	Part of the ABC transporter FtsEX involved in
O159_RS04115	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
O159_RS04120	COG2365	Tyrosine phosphatase family
O159_RS04155	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
O159_RS04175	COG0640	Transcriptional regulator
O159_RS04180	COG0483	inositol monophosphate 1-phosphatase activity
O159_RS04205	COG2801	Transposase and inactivated derivatives
O159_RS04210	COG2826	transposase and inactivated derivatives, IS30 family
O159_RS04260	COG0549	Belongs to the carbamate kinase family
O159_RS04275	COG0531	amino acid
O159_RS04280	COG2826	transposase and inactivated derivatives, IS30 family
O159_RS04310	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
O159_RS04355	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
O159_RS04380	COG0415	Belongs to the DNA photolyase family
O159_RS04405	COG2826	transposase and inactivated derivatives, IS30 family
O159_RS04410	COG2801	Transposase and inactivated derivatives
O159_RS04440	COG0631	protein serine/threonine phosphatase activity
O159_RS04445	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
O159_RS04450	COG0066	3-isopropylmalate dehydratase activity
O159_RS04455	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
O159_RS04465	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
O159_RS04470	COG1181	Belongs to the D-alanine--D-alanine ligase family
O159_RS04485	COG0742	ribosomal rna small subunit methyltransferase
O159_RS04495	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
O159_RS04505	COG0333	Belongs to the bacterial ribosomal protein bL32 family
O159_RS04510	COG0571	ribonuclease III activity
O159_RS04515	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
O159_RS04540	COG0410	ABC transporter
O159_RS04545	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
O159_RS04565	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
O159_RS04570	COG2826	transposase and inactivated derivatives, IS30 family
O159_RS04590	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
O159_RS04595	COG0228	four-way junction DNA binding
O159_RS04600	COG1837	Belongs to the UPF0109 family
O159_RS04605	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
O159_RS04615	COG0336	Belongs to the RNA methyltransferase TrmD family
O159_RS04630	COG0335	large ribosomal subunit rRNA binding
O159_RS04635	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
O159_RS04645	COG0792	nuclease activity
O159_RS04660	COG4974	Belongs to the 'phage' integrase family
O159_RS04670	COG0477	Major facilitator Superfamily
O159_RS04675	COG0052	Belongs to the universal ribosomal protein uS2 family
O159_RS04680	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
O159_RS04685	COG0528	UMP kinase activity
O159_RS04690	COG0233	cytoplasmic translational termination
O159_RS04735	COG3118	belongs to the thioredoxin family
O159_RS04740	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
O159_RS04745	COG0366	Alpha amylase catalytic
O159_RS04775	COG0482	sulfurtransferase activity
O159_RS04780	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
O159_RS04790	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
O159_RS04795	COG0154	amidase activity
O159_RS04800	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
O159_RS04805	COG0318	PFAM AMP-dependent synthetase and ligase
O159_RS04825	COG0667	Aldo Keto reductase
O159_RS04830	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
O159_RS04845	COG4721	ABC-type cobalt transport system, permease component
O159_RS04850	COG4172	Belongs to the ABC transporter superfamily
O159_RS04860	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
O159_RS04890	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
O159_RS04920	COG2963	transposase activity
O159_RS04935	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
O159_RS04940	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
O159_RS04950	COG0187	DNA topoisomerase II activity
O159_RS04955	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
O159_RS04980	COG0756	dUTP diphosphatase activity
O159_RS05000	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
O159_RS05005	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
O159_RS05030	COG1024	Enoyl-CoA hydratase
O159_RS05030	COG1250	3-hydroxyacyl-CoA dehydrogenase
O159_RS05035	COG0183	Belongs to the thiolase family
O159_RS05040	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
O159_RS05085	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
O159_RS05090	COG2826	transposase and inactivated derivatives, IS30 family
O159_RS05115	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
O159_RS05135	COG4932	domain protein
O159_RS05135	COG2373	Large extracellular alpha-helical protein
O159_RS05135	COG1388	LysM domain
O159_RS05150	COG3876	Protein conserved in bacteria
O159_RS05155	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
O159_RS05165	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
O159_RS05175	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
O159_RS05180	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
O159_RS05185	COG0217	transcriptional regulatory protein
O159_RS05190	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
O159_RS05195	COG0632	four-way junction helicase activity
O159_RS05200	COG2255	four-way junction helicase activity
O159_RS05210	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
O159_RS05215	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
O159_RS05225	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
O159_RS05235	COG1196	nuclear chromosome segregation
O159_RS05240	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
O159_RS05250	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
O159_RS05265	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
O159_RS05270	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
O159_RS05280	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
O159_RS05285	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
O159_RS05290	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
O159_RS05295	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
O159_RS05305	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
O159_RS05310	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
O159_RS05315	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
O159_RS05335	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
O159_RS05340	COG0540	Belongs to the ATCase OTCase family
O159_RS05345	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
O159_RS05355	COG0505	Belongs to the CarA family
O159_RS05360	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
O159_RS05365	COG0284	orotidine-5'-phosphate decarboxylase activity
O159_RS05370	COG0194	GDP metabolic process
O159_RS05375	COG1758	RNA polymerase activity
O159_RS05385	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
O159_RS05490	COG4974	Belongs to the 'phage' integrase family
O159_RS05495	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
O159_RS05505	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
O159_RS05510	COG0140	phosphoribosyl-ATP diphosphatase activity
O159_RS05515	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
O159_RS05520	COG0107	imidazoleglycerol-phosphate synthase activity
O159_RS05525	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
O159_RS05545	COG0134	indole-3-glycerol-phosphate synthase activity
O159_RS05550	COG0133	tryptophan synthase activity
O159_RS05555	COG0159	tryptophan synthase activity
O159_RS05570	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
O159_RS05575	COG0070	glutamate synthase
O159_RS05575	COG0069	glutamate synthase activity
O159_RS05575	COG0067	glutamate synthase
O159_RS05585	COG0469	pyruvate kinase activity
O159_RS05610	COG2826	transposase and inactivated derivatives, IS30 family
O159_RS05630	COG2050	protein possibly involved in aromatic compounds catabolism
O159_RS05645	COG0539	negative regulation of cytoplasmic translation
O159_RS05650	COG0237	dephospho-CoA kinase activity
O159_RS05655	COG0556	nucleotide-excision repair
O159_RS05670	COG0322	excinuclease ABC activity
O159_RS05675	COG1660	Displays ATPase and GTPase activities
O159_RS05680	COG1481	regulation of sporulation
O159_RS05695	COG0126	phosphoglycerate kinase activity
O159_RS05700	COG0149	triose-phosphate isomerase activity
O159_RS05705	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
O159_RS05715	COG0363	glucosamine-6-phosphate deaminase activity
O159_RS05730	COG0166	Belongs to the GPI family
O159_RS05735	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
O159_RS05745	COG0109	protoheme IX farnesyltransferase activity
O159_RS05755	COG1612	heme a metabolic process
O159_RS05775	COG0396	ATPase activity
O159_RS05780	COG2151	metal-sulfur cluster biosynthetic enzyme
O159_RS05785	COG0488	(ABC) transporter
O159_RS05805	COG1028	Short-chain dehydrogenase reductase Sdr
O159_RS05815	COG3830	Belongs to the UPF0237 family
O159_RS05815	COG0560	Phosphoserine phosphatase
O159_RS05820	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
O159_RS05825	COG0297	glycogen (starch) synthase activity
O159_RS05830	COG1119	ATPase activity
O159_RS05835	COG0254	rRNA binding
O159_RS05850	COG0366	Alpha amylase catalytic
O159_RS05880	COG1686	Belongs to the peptidase S11 family
O159_RS05900	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
O159_RS05930	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
O159_RS05940	COG1012	belongs to the aldehyde dehydrogenase family
O159_RS05945	COG1012	belongs to the aldehyde dehydrogenase family
O159_RS05955	COG0631	protein serine/threonine phosphatase activity
O159_RS05970	COG0714	Associated with various cellular activities
O159_RS06095	COG2161	toxin-antitoxin pair type II binding
O159_RS06180	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
O159_RS06195	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
O159_RS06200	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
O159_RS06205	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
O159_RS06255	COG0697	spore germination
O159_RS06260	COG0242	peptide deformylase activity
O159_RS06280	COG2826	transposase and inactivated derivatives, IS30 family
O159_RS06290	COG4608	Belongs to the ABC transporter superfamily
O159_RS06305	COG0601	transmembrane transport
O159_RS06315	COG0358	DNA primase activity
O159_RS06345	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
O159_RS06350	COG1381	Involved in DNA repair and RecF pathway recombination
O159_RS06355	COG2860	membrane
O159_RS06360	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
O159_RS06365	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
O159_RS06380	COG1136	(ABC) transporter
O159_RS06385	COG2826	transposase and inactivated derivatives, IS30 family
O159_RS06390	COG2201	protein-glutamate methylesterase activity
O159_RS06405	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
O159_RS06415	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
O159_RS06425	COG0537	adenosine 5'-monophosphoramidase activity
O159_RS06435	COG0484	heat shock protein binding
O159_RS06440	COG1420	regulation of RNA biosynthetic process
O159_RS06460	COG0481	GTPase activity
O159_RS06470	COG1090	epimerase
O159_RS06475	COG0268	Binds directly to 16S ribosomal RNA
O159_RS06500	COG0495	leucyl-tRNA aminoacylation
O159_RS06515	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
O159_RS06525	COG1294	oxidase, subunit
O159_RS06530	COG1271	oxidase subunit
O159_RS06565	COG1174	glycine betaine transport
O159_RS06590	COG0442	prolyl-tRNA aminoacylation
O159_RS06595	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
O159_RS06600	COG0750	zinc metalloprotease
O159_RS06605	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
O159_RS06615	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
O159_RS06625	COG0318	PFAM AMP-dependent synthetase and ligase
O159_RS06625	COG0204	Acyl-transferase
O159_RS06670	COG4581	dead DEAH box helicase
O159_RS06675	COG0805	protein transport
O159_RS06680	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
O159_RS06710	COG0546	phosphoglycolate phosphatase activity
O159_RS06720	COG1968	undecaprenyl-diphosphatase activity
O159_RS06725	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
O159_RS06740	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
O159_RS06750	COG1937	Protein conserved in bacteria
O159_RS06775	COG1316	TRANSCRIPTIONal
O159_RS06790	COG0799	negative regulation of ribosome biogenesis
O159_RS06800	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
O159_RS06815	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
O159_RS06820	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
O159_RS06825	COG0211	Belongs to the bacterial ribosomal protein bL27 family
O159_RS06830	COG0261	This protein binds to 23S rRNA in the presence of protein L20
O159_RS06840	COG1530	ribonuclease E activity
O159_RS06850	COG0105	UTP biosynthetic process
O159_RS06865	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
O159_RS06870	COG1309	transcriptional regulator
O159_RS06875	COG0477	Major facilitator Superfamily
O159_RS06880	COG0525	valine-tRNA ligase activity
O159_RS06910	COG0339	signal peptide processing
O159_RS06915	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
O159_RS06920	COG0740	serine-type endopeptidase activity
O159_RS06925	COG0740	serine-type endopeptidase activity
O159_RS06935	COG0544	peptidyl-prolyl cis-trans isomerase activity
O159_RS06950	COG0477	Major facilitator Superfamily
O159_RS06965	COG0783	Belongs to the Dps family
O159_RS06975	COG0698	ribose 5-phosphate isomerase
O159_RS06995	COG4585	Histidine kinase
O159_RS07000	COG2197	response regulator
O159_RS07005	COG0668	transmembrane transport
O159_RS07020	COG1946	Acyl-CoA thioesterase
O159_RS07035	COG0723	plastoquinol--plastocyanin reductase activity
O159_RS07060	COG0629	single-stranded DNA binding
O159_RS07065	COG1215	transferase activity, transferring glycosyl groups
O159_RS07065	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
O159_RS07075	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
O159_RS07080	COG0583	DNA-binding transcription factor activity
O159_RS07115	COG1492	cobalamin metabolic process
O159_RS07125	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
O159_RS07140	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
O159_RS07145	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
O159_RS07150	COG0508	dehydrogenase complex catalyzes the overall conversion of
O159_RS07165	COG0321	lipoyl(octanoyl) transferase activity
O159_RS07170	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
O159_RS07185	COG0174	glutamine synthetase
O159_RS07195	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
O159_RS07205	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
O159_RS07235	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
O159_RS07240	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
O159_RS07255	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
O159_RS07265	COG1461	Dihydroxyacetone kinase
O159_RS07270	COG2376	Dihydroxyacetone kinase
O159_RS07275	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
O159_RS07280	COG1845	cytochrome c oxidase, subunit III
O159_RS07285	COG2010	Cytochrome c
O159_RS07290	COG0723	plastoquinol--plastocyanin reductase activity
O159_RS07295	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
O159_RS07300	COG2226	methyltransferase
O159_RS07310	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
O159_RS07315	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
O159_RS07335	COG0328	RNA-DNA hybrid ribonuclease activity
O159_RS07340	COG0167	dihydroorotate dehydrogenase activity
O159_RS07345	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
O159_RS07350	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
O159_RS07360	COG0587	DNA-directed DNA polymerase activity
O159_RS07370	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
O159_RS07375	COG3599	regulation of cell shape
O159_RS07385	COG1799	cell septum assembly
O159_RS07395	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
O159_RS07405	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
O159_RS07410	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
O159_RS07420	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
O159_RS07425	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
O159_RS07435	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
O159_RS07440	COG0768	penicillin binding
O159_RS07450	COG0275	rRNA processing
O159_RS07455	COG2001	Belongs to the MraZ family
O159_RS07465	COG0142	geranyltranstransferase activity
O159_RS07475	COG3942	CHAP domain
O159_RS07475	COG1388	LysM domain
O159_RS07480	COG0515	serine threonine protein kinase
O159_RS07480	COG2815	serine threonine protein kinase
O159_RS07485	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
O159_RS07490	COG0204	Acyl-transferase
O159_RS07495	COG1940	carbohydrate kinase activity
O159_RS07500	COG1022	Amp-dependent synthetase and ligase
O159_RS07520	COG1192	Involved in chromosome partitioning
O159_RS07835	COG1716	ATPase activity
O159_RS07870	COG0484	heat shock protein binding
O159_RS07910	COG0142	geranyltranstransferase activity
O159_RS07920	COG0702	epimerase
O159_RS07930	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
O159_RS07940	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
O159_RS07960	COG2011	ABC-type metal ion transport system permease component
O159_RS07965	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
O159_RS07970	COG1464	Belongs to the NlpA lipoprotein family
O159_RS07995	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
O159_RS08000	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
O159_RS08005	COG0131	Imidazoleglycerol-phosphate dehydratase
O159_RS08010	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
O159_RS08015	COG3942	CHAP domain
O159_RS08015	COG1388	LysM domain
O159_RS08020	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
O159_RS08025	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
O159_RS08050	COG2826	transposase and inactivated derivatives, IS30 family
O159_RS08055	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
O159_RS08060	COG0473	3-isopropylmalate dehydrogenase activity
O159_RS08075	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
O159_RS08080	COG0440	acetolactate synthase activity
O159_RS08085	COG0028	Belongs to the TPP enzyme family
O159_RS08090	COG0129	dihydroxy-acid dehydratase activity
O159_RS08130	COG3387	PFAM Glycoside hydrolase 15-related
O159_RS08135	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
O159_RS08150	COG1609	Transcriptional regulator
O159_RS08160	COG1175	transmembrane transport
O159_RS08165	COG0395	ABC-type sugar transport system, permease component
O159_RS08175	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
O159_RS08185	COG0673	inositol 2-dehydrogenase activity
O159_RS08190	COG0395	ABC-type sugar transport system, permease component
O159_RS08235	COG0517	IMP dehydrogenase activity
O159_RS08235	COG4175	Glycine betaine
O159_RS08260	COG2826	transposase and inactivated derivatives, IS30 family
O159_RS08330	COG2826	transposase and inactivated derivatives, IS30 family
O159_RS08350	COG0492	ferredoxin-NADP+ reductase activity
O159_RS08355	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
O159_RS08360	COG0179	Fumarylacetoacetate (FAA) hydrolase
O159_RS08365	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
O159_RS08370	COG2826	transposase and inactivated derivatives, IS30 family
O159_RS08375	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
O159_RS08385	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
O159_RS08390	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
O159_RS08395	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
O159_RS08405	COG2137	regulation of response to DNA damage stimulus
O159_RS08410	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
O159_RS08425	COG1058	Belongs to the CinA family
O159_RS08425	COG1546	Belongs to the CinA family
O159_RS08435	COG1674	ftsk spoiiie
O159_RS08440	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
O159_RS08445	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
O159_RS08450	COG1764	response to oxidative stress
O159_RS08465	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
O159_RS08480	COG0612	Peptidase, M16
O159_RS08490	COG0667	Aldo Keto reductase
O159_RS08535	COG2837	iron assimilation
O159_RS08540	COG1217	gtp-binding protein TYPA
O159_RS08550	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
O159_RS08555	COG0601	transmembrane transport
O159_RS08575	COG4172	Belongs to the ABC transporter superfamily
O159_RS08595	COG0747	negative chemotaxis
O159_RS08605	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
O159_RS08605	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
O159_RS08610	COG0509	glycine decarboxylation via glycine cleavage system
O159_RS08615	COG0404	The glycine cleavage system catalyzes the degradation of glycine
O159_RS08625	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
O159_RS08630	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
O159_RS08640	COG1104	cysteine desulfurase activity
O159_RS08645	COG2814	Major facilitator Superfamily
O159_RS08665	COG0012	GTP binding
O159_RS08685	COG2814	Major facilitator Superfamily
O159_RS08690	COG1322	Protein conserved in bacteria
O159_RS08700	COG0191	fructose-bisphosphate aldolase activity
O159_RS08710	COG0702	epimerase
O159_RS08715	COG1733	regulation of RNA biosynthetic process
O159_RS08730	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
O159_RS08735	COG1570	exodeoxyribonuclease VII activity
O159_RS08740	COG1722	exodeoxyribonuclease VII activity
O159_RS08755	COG0114	fumarate hydratase activity
O159_RS08770	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
O159_RS08780	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
O159_RS08800	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
O159_RS08805	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
O159_RS08820	COG3214	Protein conserved in bacteria
O159_RS08830	COG2801	Transposase and inactivated derivatives
O159_RS08830	COG3415	Transposase
O159_RS08890	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
O159_RS08905	COG1804	L-carnitine dehydratase bile acid-inducible protein F
O159_RS08940	COG0148	phosphopyruvate hydratase activity
O159_RS08945	COG0124	histidyl-tRNA synthetase
O159_RS08975	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
O159_RS08985	COG0193	aminoacyl-tRNA hydrolase activity
O159_RS08990	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
O159_RS09015	COG0673	inositol 2-dehydrogenase activity
O159_RS09030	COG1175	transmembrane transport
O159_RS09100	COG3022	response to hydroperoxide
O159_RS09110	COG0355	proton-transporting ATP synthase activity, rotational mechanism
O159_RS09115	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
O159_RS09120	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
O159_RS09125	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
O159_RS09130	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
O159_RS09135	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
O159_RS09140	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
O159_RS09145	COG0356	it plays a direct role in the translocation of protons across the membrane
O159_RS09155	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
O159_RS09170	COG2890	protein-(glutamine-N5) methyltransferase activity
O159_RS09180	COG1045	serine acetyltransferase
O159_RS09185	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
O159_RS09195	COG0083	homoserine kinase activity
O159_RS09205	COG0460	homoserine dehydrogenase
O159_RS09210	COG0019	diaminopimelate decarboxylase activity
O159_RS09220	COG0018	arginyl-trna synthetase
O159_RS09235	COG1940	carbohydrate kinase activity
O159_RS09245	COG1175	transmembrane transport
O159_RS09255	COG1082	Xylose isomerase domain protein TIM barrel
O159_RS09260	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
O159_RS09270	COG0739	heme binding
O159_RS09300	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
O159_RS09305	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
O159_RS09315	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
O159_RS09330	COG1024	Enoyl-CoA hydratase
O159_RS09360	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
O159_RS09420	COG1793	dna ligase
O159_RS09460	COG1210	Utp--glucose-1-phosphate uridylyltransferase
O159_RS09490	COG3883	PFAM NLP P60 protein
O159_RS09490	COG0791	NLP P60 protein
O159_RS09515	COG0477	Major facilitator Superfamily
O159_RS09540	COG1028	Short-chain dehydrogenase reductase Sdr
O159_RS09545	COG0277	FAD linked oxidase domain protein
O159_RS09560	COG1175	transmembrane transport
O159_RS09585	COG1160	GTP binding
O159_RS09590	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
O159_RS09605	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
O159_RS09620	COG4974	Belongs to the 'phage' integrase family
O159_RS09625	COG0494	nUDIX hydrolase
O159_RS09630	COG0504	CTP synthase activity
O159_RS09650	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
O159_RS09655	COG0497	DNA recombination
O159_RS09680	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
O159_RS09705	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
O159_RS09720	COG2094	Belongs to the DNA glycosylase MPG family
O159_RS09725	COG0165	Argininosuccinate lyase
O159_RS09730	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
O159_RS09735	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
O159_RS09740	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
O159_RS09745	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
O159_RS09750	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
O159_RS09760	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
O159_RS09760	COG0072	phenylalanine-tRNA ligase activity
O159_RS09765	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
O159_RS09770	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
O159_RS09780	COG2205	protein histidine kinase activity
O159_RS09785	COG0745	RESPONSE REGULATOR receiver
O159_RS09805	COG1136	(ABC) transporter
O159_RS09815	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
O159_RS09820	COG0291	Belongs to the bacterial ribosomal protein bL35 family
O159_RS09825	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
O159_RS09845	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
O159_RS09850	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
O159_RS09875	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
O159_RS09890	COG2197	response regulator
O159_RS09900	COG2814	Major facilitator Superfamily
O159_RS09930	COG0515	serine threonine protein kinase
O159_RS09965	COG1902	pentaerythritol trinitrate reductase activity
O159_RS09985	COG0567	Dehydrogenase, E1 component
O159_RS09985	COG0508	dehydrogenase complex catalyzes the overall conversion of
O159_RS09995	COG1595	DNA-templated transcription, initiation
O159_RS10000	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
O159_RS10030	COG0601	transmembrane transport
O159_RS10070	COG0653	protein targeting
O159_RS10075	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
O159_RS10085	COG5401	PFAM Sporulation and spore germination
O159_RS10090	COG5002	protein histidine kinase activity
O159_RS10090	COG5000	phosphorelay sensor kinase activity
O159_RS10095	COG0745	RESPONSE REGULATOR receiver
O159_RS10115	COG0714	Associated with various cellular activities
O159_RS10135	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
O159_RS10140	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
O159_RS10145	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
O159_RS10180	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
O159_RS10440	COG0038	chloride channel
O159_RS10450	COG0387	Pfam Sodium calcium exchanger
O159_RS10460	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
O159_RS10465	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
O159_RS10470	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
O159_RS10475	COG0101	tRNA pseudouridine synthase activity
O159_RS10480	COG0203	ribosomal protein L17
O159_RS10485	COG0202	RNA polymerase activity
O159_RS10490	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
O159_RS10495	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
O159_RS10500	COG0257	Belongs to the bacterial ribosomal protein bL36 family
O159_RS10505	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
O159_RS10510	COG0024	Methionine aminopeptidase
O159_RS10515	COG0563	adenylate kinase activity
O159_RS10525	COG0200	Binds to the 23S rRNA
O159_RS10530	COG1841	ribosomal large subunit assembly
O159_RS10535	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
O159_RS10540	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
O159_RS10545	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
O159_RS10550	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
O159_RS10555	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
O159_RS10560	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
O159_RS10565	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
O159_RS10570	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
O159_RS10575	COG0255	Belongs to the universal ribosomal protein uL29 family
O159_RS10580	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
O159_RS10585	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
O159_RS10590	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
O159_RS10595	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
O159_RS10600	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
O159_RS10605	COG0089	rRNA binding
O159_RS10610	COG0088	Forms part of the polypeptide exit tunnel
O159_RS10615	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
O159_RS10620	COG0051	transcription antitermination factor activity, RNA binding
O159_RS10635	COG2826	transposase and inactivated derivatives, IS30 family
O159_RS10655	COG0470	DNA polymerase III
O159_RS10660	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
O159_RS10665	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
O159_RS10665	COG1754	DNA topoisomerase type I activity
O159_RS10695	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
O159_RS10705	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
O159_RS10725	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
O159_RS10740	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
O159_RS10770	COG0579	oxidoreductase
O159_RS10785	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
O159_RS10820	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
O159_RS10865	COG2115	Belongs to the xylose isomerase family
O159_RS10895	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
O159_RS10930	COG1132	(ABC) transporter
O159_RS10965	COG2801	Transposase and inactivated derivatives
O159_RS10965	COG3415	Transposase
O159_RS10970	COG2814	Major facilitator Superfamily
O159_RS10980	COG0222	ribosome binding
O159_RS10985	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
O159_RS10995	COG2205	protein histidine kinase activity
O159_RS11000	COG0745	RESPONSE REGULATOR receiver
O159_RS11010	COG1136	(ABC) transporter
O159_RS11020	COG2801	Transposase and inactivated derivatives
O159_RS11020	COG3415	Transposase
O159_RS11025	COG4565	transcriptional regulatory protein
O159_RS11035	COG1301	dicarboxylic acid transport
O159_RS11080	COG2814	Major facilitator Superfamily
O159_RS11115	COG0667	Aldo Keto reductase
O159_RS11130	COG0438	transferase activity, transferring glycosyl groups
O159_RS11155	COG3403	YqcI/YcgG family
O159_RS11200	COG0514	ATP-dependent DNA helicase (RecQ)
O159_RS11205	COG1113	amino acid transport
O159_RS11215	COG1122	ATPase activity
O159_RS11235	COG2197	response regulator
O159_RS11300	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
O159_RS11430	COG3415	Transposase
O159_RS11430	COG2801	Transposase and inactivated derivatives
O159_RS11435	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
O159_RS11440	COG3237	CsbD-like
O159_RS11465	COG0671	phosphoesterase, PA-phosphatase related
O159_RS11470	COG2226	methyltransferase
O159_RS11540	COG1316	TRANSCRIPTIONal
O159_RS11550	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
O159_RS11560	COG0077	Prephenate dehydratase
O159_RS11595	COG2189	Belongs to the N(4) N(6)-methyltransferase family
O159_RS11605	COG0095	Lipoate-protein ligase
O159_RS11665	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
O159_RS11670	COG1472	Belongs to the glycosyl hydrolase 3 family
O159_RS11675	COG0395	ABC-type sugar transport system, permease component
O159_RS11690	COG3104	oligopeptide transport
O159_RS11700	COG0745	RESPONSE REGULATOR receiver
O159_RS11705	COG2205	protein histidine kinase activity
O159_RS11710	COG1012	belongs to the aldehyde dehydrogenase family
O159_RS11715	COG0583	DNA-binding transcription factor activity
O159_RS11820	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
O159_RS11850	COG4948	Mandelate Racemase Muconate Lactonizing
O159_RS11855	COG0647	UMP catabolic process
O159_RS11880	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
O159_RS11890	COG0785	Cytochrome C biogenesis protein
O159_RS11900	COG0406	alpha-ribazole phosphatase activity
O159_RS11905	COG0017	Asparaginyl-tRNA synthetase
O159_RS11910	COG2003	Belongs to the UPF0758 family
O159_RS11915	COG2801	Transposase and inactivated derivatives
O159_RS11915	COG3415	Transposase
O159_RS11920	COG0542	response to heat
O159_RS11935	COG1113	amino acid transport
O159_RS11960	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
O159_RS11965	COG2813	Specifically methylates the guanine in position
O159_RS11990	COG0789	Transcriptional regulator
O159_RS11995	COG0484	heat shock protein binding
O159_RS12000	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
O159_RS12005	COG0443	Heat shock 70 kDa protein
O159_RS12025	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
O159_RS12035	COG2826	transposase and inactivated derivatives, IS30 family
O159_RS12040	COG0717	Belongs to the dCTP deaminase family
O159_RS12055	COG2188	Transcriptional regulator
O159_RS12090	COG1278	Cold shock
O159_RS12095	COG1230	cation diffusion facilitator family transporter
O159_RS12110	COG4067	protein conserved in archaea
O159_RS12110	COG0189	ligase activity
O159_RS12115	COG0189	ligase activity
O159_RS12115	COG0569	domain protein
O159_RS12130	COG2409	Drug exporters of the RND superfamily
O159_RS12135	COG2826	transposase and inactivated derivatives, IS30 family
O159_RS12140	COG0151	Belongs to the GarS family
O159_RS12145	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
O159_RS12150	COG2514	catechol 2,3-dioxygenase activity
O159_RS12155	COG2826	transposase and inactivated derivatives, IS30 family
O159_RS12185	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
O159_RS12190	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
O159_RS12195	COG0047	phosphoribosylformylglycinamidine synthase activity
O159_RS12230	COG4989	oxidoreductase activity
O159_RS12325	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
O159_RS12400	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
O159_RS12415	COG0776	regulation of translation
O159_RS12420	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
O159_RS12425	COG0267	Belongs to the bacterial ribosomal protein bL33 family
O159_RS12430	COG0227	Belongs to the bacterial ribosomal protein bL28 family
O159_RS12445	COG1121	(ABC) transporter
O159_RS12455	COG0508	dehydrogenase complex catalyzes the overall conversion of
O159_RS12460	COG0022	dehydrogenase e1 component
O159_RS12470	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
O159_RS12480	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
O159_RS12495	COG3415	Transposase
O159_RS12495	COG2801	Transposase and inactivated derivatives
O159_RS12525	COG1215	transferase activity, transferring glycosyl groups
O159_RS12535	COG1609	Transcriptional regulator
O159_RS12560	COG1472	Belongs to the glycosyl hydrolase 3 family
O159_RS12590	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
O159_RS12645	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
O159_RS12665	COG1605	Chorismate mutase
O159_RS12665	COG0287	Prephenate dehydrogenase
O159_RS12680	COG1215	transferase activity, transferring glycosyl groups
O159_RS12700	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
O159_RS12710	COG4172	Belongs to the ABC transporter superfamily
O159_RS12715	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
O159_RS12735	COG1054	Belongs to the UPF0176 family
O159_RS12740	COG1216	Glycosyl transferase, family 2
O159_RS12745	COG1881	PFAM PEBP family protein
O159_RS12755	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
O159_RS12785	COG2801	Transposase and inactivated derivatives
O159_RS12785	COG3415	Transposase
O159_RS12805	COG1175	transmembrane transport
O159_RS12830	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
O159_RS12840	COG0305	Participates in initiation and elongation during chromosome replication
O159_RS12845	COG0359	binds to the 23S rRNA
O159_RS12850	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
O159_RS12860	COG0360	Binds together with S18 to 16S ribosomal RNA
O159_RS12865	COG0617	tRNA 3'-terminal CCA addition
O159_RS12880	COG0492	ferredoxin-NADP+ reductase activity
O159_RS12885	COG3118	belongs to the thioredoxin family
O159_RS12890	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
O159_RS12900	COG1475	DNA binding
O159_RS12905	COG1192	Involved in chromosome partitioning
O159_RS12910	COG0357	Ribosomal RNA small subunit methyltransferase G
O159_RS12920	COG0706	membrane insertase activity
O159_RS12925	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
O159_RS12930	COG0594	ribonuclease P activity
O159_RS12935	COG0230	Belongs to the bacterial ribosomal protein bL34 family
O159_RS13060	COG2826	transposase and inactivated derivatives, IS30 family
O159_RS13120	COG1404	Belongs to the peptidase S8 family
O159_RS13130	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
O159_RS13230	COG2826	transposase and inactivated derivatives, IS30 family
O159_RS13305	COG3338	carbonate dehydratase activity
O159_RS13415	COG3290	protein histidine kinase activity
O159_RS13515	COG1802	Transcriptional regulator