locus-tag	class	description
LXX_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LXX_RS00010	COG0592	DNA-directed DNA polymerase activity
LXX_RS00015	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
LXX_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LXX_RS00025	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
LXX_RS00030	COG0187	DNA topoisomerase II activity
LXX_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LXX_RS00070	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LXX_RS00075	COG0494	nUDIX hydrolase
LXX_RS00090	COG0705	Rhomboid family
LXX_RS00100	COG3764	Sortase (surface protein transpeptidase)
LXX_RS00120	COG0515	serine threonine protein kinase
LXX_RS00125	COG0768	penicillin binding
LXX_RS00140	COG1716	ATPase activity
LXX_RS00175	COG4214	carbohydrate transport
LXX_RS00180	COG4213	ABC transporter substrate-binding protein
LXX_RS00220	COG2801	Transposase and inactivated derivatives
LXX_RS00220	COG3415	Transposase
LXX_RS00260	COG1846	Transcriptional regulator
LXX_RS00260	COG1940	carbohydrate kinase activity
LXX_RS00305	COG1414	Transcriptional regulator
LXX_RS00335	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LXX_RS00340	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LXX_RS00355	COG1959	2 iron, 2 sulfur cluster binding
LXX_RS00355	COG1295	ribonuclease BN
LXX_RS00380	COG2610	gluconate transmembrane transporter activity
LXX_RS00385	COG0246	Mannitol dehydrogenase
LXX_RS00390	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LXX_RS00400	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LXX_RS00420	COG4948	Mandelate Racemase Muconate Lactonizing
LXX_RS00430	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
LXX_RS00435	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LXX_RS00435	COG3711	transcriptional antiterminator
LXX_RS00450	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
LXX_RS00495	COG3590	peptidase
LXX_RS00505	COG0423	glycine-tRNA ligase activity
LXX_RS00510	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LXX_RS00515	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LXX_RS00540	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
LXX_RS00545	COG0181	hydroxymethylbilane synthase activity
LXX_RS00555	COG0113	porphobilinogen synthase activity
LXX_RS00560	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LXX_RS00600	COG0604	alcohol dehydrogenase
LXX_RS00620	COG1216	Glycosyl transferase, family 2
LXX_RS00625	COG1881	PFAM PEBP family protein
LXX_RS00635	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
LXX_RS00650	COG0017	Asparaginyl-tRNA synthetase
LXX_RS00655	COG0406	alpha-ribazole phosphatase activity
LXX_RS00665	COG0785	Cytochrome C biogenesis protein
LXX_RS00675	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LXX_RS00700	COG0647	UMP catabolic process
LXX_RS00705	COG4948	Mandelate Racemase Muconate Lactonizing
LXX_RS00735	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
LXX_RS00745	COG2189	Belongs to the N(4) N(6)-methyltransferase family
LXX_RS00785	COG2801	Transposase and inactivated derivatives
LXX_RS00810	COG0745	RESPONSE REGULATOR receiver
LXX_RS00815	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LXX_RS00855	COG0569	domain protein
LXX_RS00860	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LXX_RS00865	COG0640	Transcriptional regulator
LXX_RS00885	COG1802	Transcriptional regulator
LXX_RS00900	COG2226	methyltransferase
LXX_RS00905	COG0142	geranyltranstransferase activity
LXX_RS00920	COG1666	GTP binding
LXX_RS00935	COG2197	response regulator
LXX_RS00940	COG2755	lipolytic protein G-D-S-L family
LXX_RS00940	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
LXX_RS01010	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LXX_RS01050	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LXX_RS01080	COG0671	phosphoesterase, PA-phosphatase related
LXX_RS01120	COG1316	TRANSCRIPTIONal
LXX_RS01130	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LXX_RS01140	COG0077	Prephenate dehydratase
LXX_RS01225	COG0583	DNA-binding transcription factor activity
LXX_RS01230	COG1012	belongs to the aldehyde dehydrogenase family
LXX_RS01235	COG2205	protein histidine kinase activity
LXX_RS01240	COG0745	RESPONSE REGULATOR receiver
LXX_RS01245	COG3104	oligopeptide transport
LXX_RS01255	COG1175	transmembrane transport
LXX_RS01260	COG0395	ABC-type sugar transport system, permease component
LXX_RS01265	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
LXX_RS01270	COG1737	Transcriptional regulator
LXX_RS01340	COG0025	NhaP-type Na H and K H
LXX_RS01350	COG2030	dehydratase
LXX_RS01360	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LXX_RS01380	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LXX_RS01390	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LXX_RS01395	COG0081	regulation of translation
LXX_RS01405	COG3321	synthase
LXX_RS01405	COG0604	alcohol dehydrogenase
LXX_RS01435	COG0673	inositol 2-dehydrogenase activity
LXX_RS01465	COG1136	(ABC) transporter
LXX_RS01475	COG0745	RESPONSE REGULATOR receiver
LXX_RS01480	COG2205	protein histidine kinase activity
LXX_RS01490	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LXX_RS01495	COG0222	ribosome binding
LXX_RS01510	COG1132	(ABC) transporter
LXX_RS01590	COG1070	Carbohydrate kinase
LXX_RS01595	COG2115	Belongs to the xylose isomerase family
LXX_RS01620	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LXX_RS01630	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LXX_RS01645	COG0579	oxidoreductase
LXX_RS01670	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LXX_RS01680	COG0431	NADPH-dependent FMN reductase
LXX_RS01720	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LXX_RS01730	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LXX_RS01990	COG1754	DNA topoisomerase type I activity
LXX_RS01990	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LXX_RS01995	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LXX_RS02000	COG0470	DNA polymerase III
LXX_RS02025	COG2337	Toxic component of a toxin-antitoxin (TA) module
LXX_RS02040	COG2027	D-alanyl-D-alanine carboxypeptidase
LXX_RS02075	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
LXX_RS02080	COG1132	(ABC) transporter
LXX_RS02120	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
LXX_RS02125	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LXX_RS02125	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LXX_RS02160	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LXX_RS02165	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LXX_RS02175	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LXX_RS02180	COG0180	Tryptophanyl-tRNA synthetase
LXX_RS02185	COG0708	Exodeoxyribonuclease III
LXX_RS02220	COG2009	succinate dehydrogenase
LXX_RS02255	COG3845	ABC transporter
LXX_RS02260	COG4603	Belongs to the binding-protein-dependent transport system permease family
LXX_RS02265	COG1079	Belongs to the binding-protein-dependent transport system permease family
LXX_RS02280	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LXX_RS02285	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LXX_RS02295	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LXX_RS02310	COG0025	NhaP-type Na H and K H
LXX_RS02315	COG4770	biotin carboxylase activity
LXX_RS02320	COG0424	maF-like protein
LXX_RS02350	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LXX_RS02400	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
LXX_RS02425	COG1215	transferase activity, transferring glycosyl groups
LXX_RS02475	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LXX_RS02480	COG1086	Polysaccharide biosynthesis protein
LXX_RS02490	COG0438	transferase activity, transferring glycosyl groups
LXX_RS02510	COG1216	Glycosyl transferase, family 2
LXX_RS02525	COG1482	cell wall glycoprotein biosynthetic process
LXX_RS02580	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LXX_RS02585	COG0714	Associated with various cellular activities
LXX_RS02605	COG0745	RESPONSE REGULATOR receiver
LXX_RS02610	COG5002	protein histidine kinase activity
LXX_RS02615	COG5401	PFAM Sporulation and spore germination
LXX_RS02620	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LXX_RS02625	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LXX_RS02630	COG0653	protein targeting
LXX_RS02655	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LXX_RS02705	COG1793	dna ligase
LXX_RS02745	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LXX_RS02750	COG0497	DNA recombination
LXX_RS02765	COG0504	CTP synthase activity
LXX_RS02770	COG0494	nUDIX hydrolase
LXX_RS02775	COG4974	Belongs to the 'phage' integrase family
LXX_RS02790	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LXX_RS02805	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
LXX_RS02810	COG1160	GTP binding
LXX_RS02875	COG3883	PFAM NLP P60 protein
LXX_RS02875	COG0791	NLP P60 protein
LXX_RS02900	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LXX_RS02930	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LXX_RS02935	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LXX_RS02940	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LXX_RS02940	COG0072	phenylalanine-tRNA ligase activity
LXX_RS02965	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LXX_RS02970	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LXX_RS02975	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LXX_RS02980	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LXX_RS02985	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LXX_RS02990	COG0165	Argininosuccinate lyase
LXX_RS02995	COG2094	Belongs to the DNA glycosylase MPG family
LXX_RS03010	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LXX_RS03035	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LXX_RS03060	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LXX_RS03100	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LXX_RS03110	COG1157	protein secretion by the type III secretion system
LXX_RS03120	COG0791	NLP P60 protein
LXX_RS03155	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LXX_RS03160	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
LXX_RS03175	COG1024	Enoyl-CoA hydratase
LXX_RS03180	COG0010	Belongs to the arginase family
LXX_RS03190	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
LXX_RS03200	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LXX_RS03205	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LXX_RS03220	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LXX_RS03220	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LXX_RS03220	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LXX_RS03245	COG1929	Belongs to the glycerate kinase type-1 family
LXX_RS03255	COG1082	Xylose isomerase domain protein TIM barrel
LXX_RS03275	COG0395	ABC-type sugar transport system, permease component
LXX_RS03280	COG1940	carbohydrate kinase activity
LXX_RS03285	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LXX_RS03300	COG0018	arginyl-trna synthetase
LXX_RS03335	COG2801	Transposase and inactivated derivatives
LXX_RS03335	COG3415	Transposase
LXX_RS03350	COG0019	diaminopimelate decarboxylase activity
LXX_RS03355	COG0460	homoserine dehydrogenase
LXX_RS03365	COG0083	homoserine kinase activity
LXX_RS03375	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LXX_RS03380	COG1045	serine acetyltransferase
LXX_RS03390	COG2890	protein-(glutamine-N5) methyltransferase activity
LXX_RS03405	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LXX_RS03415	COG0356	it plays a direct role in the translocation of protons across the membrane
LXX_RS03420	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LXX_RS03425	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LXX_RS03430	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LXX_RS03435	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LXX_RS03440	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LXX_RS03445	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LXX_RS03450	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LXX_RS03460	COG3022	response to hydroperoxide
LXX_RS03465	COG2818	Glycosylase
LXX_RS03470	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LXX_RS03485	COG0195	Participates in both transcription termination and antitermination
LXX_RS03495	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LXX_RS03500	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LXX_RS03545	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LXX_RS03560	COG0196	riboflavin kinase activity
LXX_RS03570	COG2390	Transcriptional regulator
LXX_RS03580	COG1012	belongs to the aldehyde dehydrogenase family
LXX_RS03585	COG1012	belongs to the aldehyde dehydrogenase family
LXX_RS03605	COG0748	coenzyme F420 binding
LXX_RS03615	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
LXX_RS03620	COG1937	Protein conserved in bacteria
LXX_RS03665	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LXX_RS03675	COG2197	response regulator
LXX_RS03695	COG3321	synthase
LXX_RS03695	COG0604	alcohol dehydrogenase
LXX_RS03825	COG2826	transposase and inactivated derivatives, IS30 family
LXX_RS03870	COG0544	peptidyl-prolyl cis-trans isomerase activity
LXX_RS03880	COG0740	serine-type endopeptidase activity
LXX_RS03885	COG0740	serine-type endopeptidase activity
LXX_RS03890	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LXX_RS03915	COG0525	valine-tRNA ligase activity
LXX_RS03925	COG1309	transcriptional regulator
LXX_RS03930	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LXX_RS03935	COG0285	dihydrofolate synthase activity
LXX_RS03945	COG0105	UTP biosynthetic process
LXX_RS03955	COG1530	ribonuclease E activity
LXX_RS03965	COG0261	This protein binds to 23S rRNA in the presence of protein L20
LXX_RS03970	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LXX_RS03975	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LXX_RS03980	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LXX_RS03985	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LXX_RS03995	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LXX_RS04005	COG0799	negative regulation of ribosome biogenesis
LXX_RS04020	COG1316	TRANSCRIPTIONal
LXX_RS04070	COG0546	phosphoglycolate phosphatase activity
LXX_RS04100	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LXX_RS04105	COG0805	protein transport
LXX_RS04110	COG4581	dead DEAH box helicase
LXX_RS04200	COG0358	DNA primase activity
LXX_RS04210	COG0601	transmembrane transport
LXX_RS04245	COG0242	peptide deformylase activity
LXX_RS04250	COG0697	spore germination
LXX_RS04300	COG0668	transmembrane transport
LXX_RS04305	COG2197	response regulator
LXX_RS04310	COG4585	Histidine kinase
LXX_RS04330	COG0698	ribose 5-phosphate isomerase
LXX_RS04340	COG0783	Belongs to the Dps family
LXX_RS04345	COG0477	Major facilitator Superfamily
LXX_RS04415	COG4974	Belongs to the 'phage' integrase family
LXX_RS04435	COG2233	PERMEase
LXX_RS04440	COG2252	PERMEase
LXX_RS04445	COG0220	tRNA (guanine-N7-)-methyltransferase activity
LXX_RS04455	COG0179	Fumarylacetoacetate (FAA) hydrolase
LXX_RS04460	COG0277	FAD linked oxidase domain protein
LXX_RS04465	COG0545	Peptidyl-prolyl cis-trans isomerase
LXX_RS04480	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LXX_RS04495	COG1185	polyribonucleotide nucleotidyltransferase activity
LXX_RS04500	COG2171	N-acyltransferase activity
LXX_RS04505	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LXX_RS04540	COG2239	Acts as a magnesium transporter
LXX_RS04550	COG0006	proline dipeptidase activity
LXX_RS04565	COG0513	Belongs to the DEAD box helicase family
LXX_RS04590	COG0210	DNA helicase
LXX_RS04625	COG3480	Lon protease (S16) C-terminal proteolytic domain
LXX_RS04630	COG1615	UPF0182 protein
LXX_RS04640	COG2204	response regulator
LXX_RS04660	COG5002	protein histidine kinase activity
LXX_RS04715	COG4175	Glycine betaine
LXX_RS04725	COG3448	diguanylate cyclase activity
LXX_RS04725	COG4175	Glycine betaine
LXX_RS04730	COG4176	ABC-type proline glycine betaine transport system permease component
LXX_RS04735	COG0415	Belongs to the DNA photolyase family
LXX_RS04750	COG0666	response to abiotic stimulus
LXX_RS04790	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LXX_RS04795	COG0066	3-isopropylmalate dehydratase activity
LXX_RS04800	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LXX_RS04810	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LXX_RS04815	COG1181	Belongs to the D-alanine--D-alanine ligase family
LXX_RS04830	COG0742	ribosomal rna small subunit methyltransferase
LXX_RS04840	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LXX_RS04850	COG0333	Belongs to the bacterial ribosomal protein bL32 family
LXX_RS04855	COG0571	ribonuclease III activity
LXX_RS04860	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LXX_RS04870	COG0640	Transcriptional regulator
LXX_RS04880	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LXX_RS04885	COG0723	plastoquinol--plastocyanin reductase activity
LXX_RS04890	COG2010	Cytochrome c
LXX_RS04895	COG1845	cytochrome c oxidase, subunit III
LXX_RS04900	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LXX_RS04905	COG2376	Dihydroxyacetone kinase
LXX_RS04910	COG1461	Dihydroxyacetone kinase
LXX_RS04920	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LXX_RS04935	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LXX_RS04940	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LXX_RS04970	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
LXX_RS04980	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
LXX_RS04995	COG0174	glutamine synthetase
LXX_RS05010	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LXX_RS05015	COG0321	lipoyl(octanoyl) transferase activity
LXX_RS05025	COG0508	dehydrogenase complex catalyzes the overall conversion of
LXX_RS05030	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LXX_RS05035	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LXX_RS05050	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LXX_RS05055	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LXX_RS05060	COG1492	cobalamin metabolic process
LXX_RS05085	COG1757	Na H antiporter
LXX_RS05100	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LXX_RS05105	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LXX_RS05115	COG0187	DNA topoisomerase II activity
LXX_RS05120	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LXX_RS05125	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
LXX_RS05145	COG0756	dUTP diphosphatase activity
LXX_RS05165	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LXX_RS05170	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LXX_RS05175	COG1250	3-hydroxyacyl-CoA dehydrogenase
LXX_RS05175	COG1024	Enoyl-CoA hydratase
LXX_RS05185	COG1024	Enoyl-CoA hydratase
LXX_RS05185	COG1250	3-hydroxyacyl-CoA dehydrogenase
LXX_RS05190	COG0183	Belongs to the thiolase family
LXX_RS05195	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
LXX_RS05220	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LXX_RS05230	COG0004	ammonium transporteR
LXX_RS05240	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
LXX_RS05245	COG1051	belongs to the nudix hydrolase family
LXX_RS05275	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LXX_RS05285	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
LXX_RS05295	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
LXX_RS05300	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
LXX_RS05305	COG0217	transcriptional regulatory protein
LXX_RS05310	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
LXX_RS05315	COG0632	four-way junction helicase activity
LXX_RS05320	COG2255	four-way junction helicase activity
LXX_RS05330	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LXX_RS05335	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LXX_RS05345	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LXX_RS05355	COG1196	nuclear chromosome segregation
LXX_RS05360	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LXX_RS05370	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LXX_RS05385	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LXX_RS05390	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LXX_RS05400	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LXX_RS05405	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LXX_RS05410	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LXX_RS05415	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LXX_RS05425	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
LXX_RS05430	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LXX_RS05435	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LXX_RS05465	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LXX_RS05470	COG0540	Belongs to the ATCase OTCase family
LXX_RS05475	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LXX_RS05485	COG0505	Belongs to the CarA family
LXX_RS05490	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LXX_RS05495	COG0284	orotidine-5'-phosphate decarboxylase activity
LXX_RS05500	COG0194	GDP metabolic process
LXX_RS05505	COG1758	RNA polymerase activity
LXX_RS05515	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LXX_RS05525	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LXX_RS05535	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LXX_RS05540	COG0140	phosphoribosyl-ATP diphosphatase activity
LXX_RS05545	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
LXX_RS05550	COG0107	imidazoleglycerol-phosphate synthase activity
LXX_RS05555	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LXX_RS05575	COG0134	indole-3-glycerol-phosphate synthase activity
LXX_RS05580	COG0133	tryptophan synthase activity
LXX_RS05585	COG0159	tryptophan synthase activity
LXX_RS05590	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LXX_RS05595	COG0067	glutamate synthase
LXX_RS05595	COG0069	glutamate synthase activity
LXX_RS05595	COG0070	glutamate synthase
LXX_RS05635	COG2050	protein possibly involved in aromatic compounds catabolism
LXX_RS05650	COG0539	negative regulation of cytoplasmic translation
LXX_RS05655	COG0237	dephospho-CoA kinase activity
LXX_RS05660	COG0556	nucleotide-excision repair
LXX_RS05680	COG0322	excinuclease ABC activity
LXX_RS05685	COG1660	Displays ATPase and GTPase activities
LXX_RS05690	COG1481	regulation of sporulation
LXX_RS05705	COG0126	phosphoglycerate kinase activity
LXX_RS05710	COG0149	triose-phosphate isomerase activity
LXX_RS05715	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LXX_RS05725	COG0363	glucosamine-6-phosphate deaminase activity
LXX_RS05745	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LXX_RS05755	COG0109	protoheme IX farnesyltransferase activity
LXX_RS05760	COG1612	heme a metabolic process
LXX_RS05780	COG0396	ATPase activity
LXX_RS05785	COG2151	metal-sulfur cluster biosynthetic enzyme
LXX_RS05790	COG0488	(ABC) transporter
LXX_RS05810	COG1028	Short-chain dehydrogenase reductase Sdr
LXX_RS05815	COG3830	Belongs to the UPF0237 family
LXX_RS05815	COG0560	Phosphoserine phosphatase
LXX_RS05820	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LXX_RS05830	COG1119	ATPase activity
LXX_RS05835	COG0254	rRNA binding
LXX_RS05850	COG0366	Alpha amylase catalytic
LXX_RS05875	COG0406	alpha-ribazole phosphatase activity
LXX_RS05890	COG1686	Belongs to the peptidase S11 family
LXX_RS05895	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LXX_RS05920	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LXX_RS05935	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LXX_RS05950	COG1012	belongs to the aldehyde dehydrogenase family
LXX_RS05960	COG0631	protein serine/threonine phosphatase activity
LXX_RS05965	COG0515	serine threonine protein kinase
LXX_RS05965	COG2815	serine threonine protein kinase
LXX_RS05975	COG0714	Associated with various cellular activities
LXX_RS06005	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LXX_RS06015	COG0204	Acyl-transferase
LXX_RS06015	COG0318	PFAM AMP-dependent synthetase and ligase
LXX_RS06025	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LXX_RS06035	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
LXX_RS06040	COG0750	zinc metalloprotease
LXX_RS06045	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
LXX_RS06050	COG0442	prolyl-tRNA aminoacylation
LXX_RS06075	COG1174	glycine betaine transport
LXX_RS06100	COG1271	oxidase subunit
LXX_RS06105	COG1294	oxidase, subunit
LXX_RS06115	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LXX_RS06130	COG0495	leucyl-tRNA aminoacylation
LXX_RS06150	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LXX_RS06160	COG0052	Belongs to the universal ribosomal protein uS2 family
LXX_RS06165	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LXX_RS06170	COG0528	UMP kinase activity
LXX_RS06175	COG0233	cytoplasmic translational termination
LXX_RS06220	COG3118	belongs to the thioredoxin family
LXX_RS06225	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LXX_RS06230	COG0366	Alpha amylase catalytic
LXX_RS06285	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
LXX_RS06300	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LXX_RS06305	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LXX_RS06310	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LXX_RS06320	COG1946	Acyl-CoA thioesterase
LXX_RS06350	COG0629	single-stranded DNA binding
LXX_RS06360	COG1215	transferase activity, transferring glycosyl groups
LXX_RS06360	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LXX_RS06370	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LXX_RS06375	COG0583	DNA-binding transcription factor activity
LXX_RS06490	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LXX_RS06495	COG0179	Fumarylacetoacetate (FAA) hydrolase
LXX_RS06505	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LXX_RS06510	COG0473	3-isopropylmalate dehydrogenase activity
LXX_RS06525	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LXX_RS06530	COG0440	acetolactate synthase activity
LXX_RS06535	COG0028	Belongs to the TPP enzyme family
LXX_RS06540	COG0129	dihydroxy-acid dehydratase activity
LXX_RS06580	COG3387	PFAM Glycoside hydrolase 15-related
LXX_RS06585	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
LXX_RS06625	COG0483	inositol monophosphate 1-phosphatase activity
LXX_RS06630	COG0640	Transcriptional regulator
LXX_RS06635	COG4152	abc transporter atp-binding protein
LXX_RS06655	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LXX_RS06660	COG0531	amino acid
LXX_RS06685	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LXX_RS06690	COG2177	Part of the ABC transporter FtsEX involved in
LXX_RS06695	COG2884	Cell division ATP-binding protein ftsE
LXX_RS06700	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LXX_RS06720	COG0586	Pfam SNARE associated Golgi protein
LXX_RS06725	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LXX_RS06730	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LXX_RS06735	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LXX_RS06740	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LXX_RS06760	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LXX_RS06785	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LXX_RS06875	COG2801	Transposase and inactivated derivatives
LXX_RS06935	COG1840	ABC-type Fe3 transport system, periplasmic component
LXX_RS06940	COG3842	ATPase activity
LXX_RS06945	COG1178	ABC-type Fe3 transport system permease component
LXX_RS06985	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
LXX_RS07020	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
LXX_RS07030	COG1122	ATPase activity
LXX_RS07035	COG4721	ABC-type cobalt transport system, permease component
LXX_RS07050	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LXX_RS07075	COG0318	PFAM AMP-dependent synthetase and ligase
LXX_RS07080	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LXX_RS07085	COG0154	amidase activity
LXX_RS07090	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LXX_RS07100	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LXX_RS07105	COG0482	sulfurtransferase activity
LXX_RS07120	COG1523	belongs to the glycosyl hydrolase 13 family
LXX_RS07180	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LXX_RS07185	COG1381	Involved in DNA repair and RecF pathway recombination
LXX_RS07190	COG2860	membrane
LXX_RS07195	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LXX_RS07200	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LXX_RS07215	COG1136	(ABC) transporter
LXX_RS07220	COG2197	response regulator
LXX_RS07225	COG4585	Histidine kinase
LXX_RS07240	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LXX_RS07250	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LXX_RS07260	COG0537	adenosine 5'-monophosphoramidase activity
LXX_RS07270	COG0484	heat shock protein binding
LXX_RS07275	COG1420	regulation of RNA biosynthetic process
LXX_RS07295	COG0481	GTPase activity
LXX_RS07310	COG0268	Binds directly to 16S ribosomal RNA
LXX_RS07345	COG0477	Major facilitator Superfamily
LXX_RS07350	COG4974	Belongs to the 'phage' integrase family
LXX_RS07365	COG0792	nuclease activity
LXX_RS07375	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LXX_RS07380	COG0335	large ribosomal subunit rRNA binding
LXX_RS07390	COG0024	Methionine aminopeptidase
LXX_RS07395	COG0336	Belongs to the RNA methyltransferase TrmD family
LXX_RS07400	COG2271	Major facilitator Superfamily
LXX_RS07410	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LXX_RS07415	COG1837	Belongs to the UPF0109 family
LXX_RS07420	COG0228	four-way junction DNA binding
LXX_RS07425	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
LXX_RS07445	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LXX_RS07465	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LXX_RS07485	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LXX_RS07490	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LXX_RS07510	COG0328	RNA-DNA hybrid ribonuclease activity
LXX_RS07515	COG0167	dihydroorotate dehydrogenase activity
LXX_RS07520	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LXX_RS07525	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LXX_RS07535	COG0587	DNA-directed DNA polymerase activity
LXX_RS07545	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LXX_RS07550	COG3599	regulation of cell shape
LXX_RS07560	COG1799	cell septum assembly
LXX_RS07570	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LXX_RS07580	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LXX_RS07585	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LXX_RS07595	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LXX_RS07600	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LXX_RS07610	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LXX_RS07615	COG0768	penicillin binding
LXX_RS07625	COG0275	rRNA processing
LXX_RS07630	COG2001	Belongs to the MraZ family
LXX_RS07640	COG0142	geranyltranstransferase activity
LXX_RS07650	COG3942	CHAP domain
LXX_RS07650	COG1388	LysM domain
LXX_RS07655	COG0515	serine threonine protein kinase
LXX_RS07655	COG2815	serine threonine protein kinase
LXX_RS07660	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
LXX_RS07665	COG0204	Acyl-transferase
LXX_RS07670	COG1940	carbohydrate kinase activity
LXX_RS07675	COG1022	Amp-dependent synthetase and ligase
LXX_RS07695	COG1192	Involved in chromosome partitioning
LXX_RS07710	COG1716	ATPase activity
LXX_RS07735	COG0484	heat shock protein binding
LXX_RS07770	COG0142	geranyltranstransferase activity
LXX_RS07780	COG0702	epimerase
LXX_RS07795	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LXX_RS07800	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
LXX_RS07820	COG2011	ABC-type metal ion transport system permease component
LXX_RS07825	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LXX_RS07830	COG1464	Belongs to the NlpA lipoprotein family
LXX_RS07865	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LXX_RS07870	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LXX_RS07875	COG0131	Imidazoleglycerol-phosphate dehydratase
LXX_RS07880	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LXX_RS07885	COG1388	LysM domain
LXX_RS07890	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LXX_RS07900	COG2223	nitrite transmembrane transporter activity
LXX_RS07915	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LXX_RS07920	COG2813	Specifically methylates the guanine in position
LXX_RS07925	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LXX_RS07930	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LXX_RS07935	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LXX_RS07950	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LXX_RS07965	COG1546	Belongs to the CinA family
LXX_RS07965	COG1058	Belongs to the CinA family
LXX_RS07975	COG1674	ftsk spoiiie
LXX_RS07980	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LXX_RS07990	COG1764	response to oxidative stress
LXX_RS08005	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
LXX_RS08020	COG0612	Peptidase, M16
LXX_RS08030	COG0667	Aldo Keto reductase
LXX_RS08070	COG2837	iron assimilation
LXX_RS08075	COG1217	gtp-binding protein TYPA
LXX_RS08090	COG0601	transmembrane transport
LXX_RS08095	COG4166	transmembrane transport
LXX_RS08120	COG0747	negative chemotaxis
LXX_RS08135	COG0509	glycine decarboxylation via glycine cleavage system
LXX_RS08145	COG1309	transcriptional regulator
LXX_RS08160	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LXX_RS08175	COG1104	cysteine desulfurase activity
LXX_RS08210	COG0012	GTP binding
LXX_RS08225	COG2814	Major facilitator Superfamily
LXX_RS08230	COG1322	Protein conserved in bacteria
LXX_RS08240	COG0191	fructose-bisphosphate aldolase activity
LXX_RS08250	COG0702	epimerase
LXX_RS08270	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LXX_RS08275	COG1570	exodeoxyribonuclease VII activity
LXX_RS08280	COG1722	exodeoxyribonuclease VII activity
LXX_RS08295	COG0114	fumarate hydratase activity
LXX_RS08305	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
LXX_RS08315	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LXX_RS08335	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LXX_RS08340	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LXX_RS08365	COG3214	Protein conserved in bacteria
LXX_RS08380	COG1704	LemA family
LXX_RS08390	COG3012	SEC-C Motif Domain Protein
LXX_RS08405	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LXX_RS08440	COG1739	Uncharacterized protein family UPF0029
LXX_RS08465	COG0148	phosphopyruvate hydratase activity
LXX_RS08470	COG2801	Transposase and inactivated derivatives
LXX_RS08475	COG0124	histidyl-tRNA synthetase
LXX_RS08480	COG1120	ATPase activity
LXX_RS08485	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LXX_RS08500	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LXX_RS08515	COG0193	aminoacyl-tRNA hydrolase activity
LXX_RS08520	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
LXX_RS08525	COG4948	Mandelate Racemase Muconate Lactonizing
LXX_RS08540	COG0673	inositol 2-dehydrogenase activity
LXX_RS08575	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LXX_RS08580	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LXX_RS08595	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LXX_RS08600	COG0488	(ABC) transporter
LXX_RS08605	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LXX_RS08610	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LXX_RS08615	COG0084	hydrolase, TatD family'
LXX_RS08620	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LXX_RS08665	COG0386	Belongs to the glutathione peroxidase family
LXX_RS08730	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LXX_RS08740	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LXX_RS08740	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LXX_RS08780	COG0791	NLP P60 protein
LXX_RS08790	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LXX_RS08800	COG1278	Cold shock
LXX_RS08825	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LXX_RS08835	COG0745	RESPONSE REGULATOR receiver
LXX_RS08840	COG2205	protein histidine kinase activity
LXX_RS08860	COG0459	protein refolding
LXX_RS08880	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LXX_RS08895	COG0681	Belongs to the peptidase S26 family
LXX_RS08910	COG4565	transcriptional regulatory protein
LXX_RS08920	COG2851	Citrate transporter
LXX_RS08940	COG3842	ATPase activity
LXX_RS08955	COG4585	Histidine kinase
LXX_RS08960	COG2197	response regulator
LXX_RS08970	COG0215	cysteine-tRNA ligase activity
LXX_RS08975	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
LXX_RS08975	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
LXX_RS08980	COG1329	Transcriptional regulator
LXX_RS08995	COG5002	protein histidine kinase activity
LXX_RS09010	COG0588	phosphoglycerate mutase activity
LXX_RS09020	COG0354	folic acid binding
LXX_RS09025	COG4044	May play a role in the intracellular transport of hydrophobic ligands
LXX_RS09040	COG0745	RESPONSE REGULATOR receiver
LXX_RS09070	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LXX_RS09080	COG1595	DNA-templated transcription, initiation
LXX_RS09105	COG0038	chloride channel
LXX_RS09115	COG0387	Pfam Sodium calcium exchanger
LXX_RS09120	COG1349	DNA-binding transcription factor activity
LXX_RS09145	COG0346	lactoylglutathione lyase activity
LXX_RS09150	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LXX_RS09155	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LXX_RS09230	COG0745	RESPONSE REGULATOR receiver
LXX_RS09260	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LXX_RS09265	COG0291	Belongs to the bacterial ribosomal protein bL35 family
LXX_RS09270	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LXX_RS09290	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LXX_RS09295	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LXX_RS09320	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LXX_RS09335	COG2197	response regulator
LXX_RS09400	COG1902	pentaerythritol trinitrate reductase activity
LXX_RS09420	COG0508	dehydrogenase complex catalyzes the overall conversion of
LXX_RS09420	COG0567	Dehydrogenase, E1 component
LXX_RS09430	COG1595	DNA-templated transcription, initiation
LXX_RS09435	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LXX_RS09455	COG0444	Belongs to the ABC transporter superfamily
LXX_RS09460	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LXX_RS09500	COG1940	carbohydrate kinase activity
LXX_RS09505	COG1105	Belongs to the carbohydrate kinase PfkB family
LXX_RS09515	COG1349	DNA-binding transcription factor activity
LXX_RS09520	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LXX_RS09530	COG2814	Major facilitator Superfamily
LXX_RS09620	COG2197	response regulator
LXX_RS09650	COG1132	(ABC) transporter
LXX_RS09660	COG1834	amidinotransferase
LXX_RS09665	COG0138	bifunctional purine biosynthesis protein purh
LXX_RS09670	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LXX_RS09695	COG0045	succinate-CoA ligase (ADP-forming) activity
LXX_RS09715	COG0584	glycerophosphoryl diester phosphodiesterase
LXX_RS09730	COG0519	Catalyzes the synthesis of GMP from XMP
LXX_RS09730	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LXX_RS09745	COG0475	glutathione-regulated potassium exporter activity
LXX_RS09755	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LXX_RS09760	COG0516	GMP reductase activity
LXX_RS09775	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LXX_RS09790	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LXX_RS09805	COG0802	atpase or kinase
LXX_RS09810	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LXX_RS09815	COG0736	holo-[acyl-carrier-protein] synthase activity
LXX_RS09820	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LXX_RS09825	COG1072	(Pantothenic acid kinase))
LXX_RS09840	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LXX_RS09845	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LXX_RS09850	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LXX_RS09855	COG0101	tRNA pseudouridine synthase activity
LXX_RS09860	COG2755	lipolytic protein G-D-S-L family
LXX_RS09860	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
LXX_RS09875	COG0202	RNA polymerase activity
LXX_RS09880	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LXX_RS09885	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LXX_RS09890	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LXX_RS09895	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LXX_RS09905	COG0563	adenylate kinase activity
LXX_RS09915	COG0200	Binds to the 23S rRNA
LXX_RS09920	COG1841	ribosomal large subunit assembly
LXX_RS09925	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LXX_RS09930	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LXX_RS09935	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LXX_RS09940	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LXX_RS09945	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LXX_RS09950	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LXX_RS09955	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LXX_RS09960	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LXX_RS09965	COG0255	Belongs to the universal ribosomal protein uL29 family
LXX_RS09970	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LXX_RS09975	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LXX_RS09980	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LXX_RS09985	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LXX_RS09990	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LXX_RS09995	COG0089	rRNA binding
LXX_RS10000	COG0088	Forms part of the polypeptide exit tunnel
LXX_RS10005	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LXX_RS10010	COG0051	transcription antitermination factor activity, RNA binding
LXX_RS10040	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LXX_RS10045	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LXX_RS10050	COG0049	tRNA binding
LXX_RS10055	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LXX_RS10070	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LXX_RS10120	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LXX_RS10140	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LXX_RS10145	COG0085	RNA polymerase activity
LXX_RS10210	COG0513	Belongs to the DEAD box helicase family
LXX_RS10235	COG1201	RNA secondary structure unwinding
LXX_RS10245	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LXX_RS10250	COG1316	TRANSCRIPTIONal
LXX_RS10265	COG1268	BioY protein
LXX_RS10280	COG1122	ATPase activity
LXX_RS10305	COG1316	TRANSCRIPTIONal
LXX_RS10335	COG2847	Copper chaperone PCu(A)C
LXX_RS10495	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LXX_RS10505	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
LXX_RS10520	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LXX_RS10535	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LXX_RS10540	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LXX_RS10565	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LXX_RS10570	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LXX_RS10580	COG0302	gtp cyclohydrolase
LXX_RS10585	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LXX_RS10595	COG0037	tRNA processing
LXX_RS10600	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LXX_RS10610	COG0741	lytic transglycosylase activity
LXX_RS10610	COG0739	heme binding
LXX_RS10610	COG1196	nuclear chromosome segregation
LXX_RS10630	COG4974	Belongs to the 'phage' integrase family
LXX_RS10700	COG0367	asparagine synthase
LXX_RS10720	COG0667	Aldo Keto reductase
LXX_RS10750	COG0514	ATP-dependent DNA helicase (RecQ)
LXX_RS10755	COG1113	amino acid transport
LXX_RS10765	COG1122	ATPase activity
LXX_RS10770	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LXX_RS10780	COG2197	response regulator
LXX_RS10810	COG2957	Belongs to the agmatine deiminase family
LXX_RS10820	COG0137	argininosuccinate synthase activity
LXX_RS10830	COG2205	protein histidine kinase activity
LXX_RS10835	COG0745	RESPONSE REGULATOR receiver
LXX_RS10850	COG0577	efflux transmembrane transporter activity
LXX_RS10850	COG1136	(ABC) transporter
LXX_RS10860	COG0076	glutamate decarboxylase activity
LXX_RS10880	COG0513	Belongs to the DEAD box helicase family
LXX_RS10905	COG2986	histidine ammonia-lyase
LXX_RS10915	COG1228	amidohydrolase
LXX_RS10920	COG1879	ABC-type sugar transport system periplasmic component
LXX_RS10925	COG1129	ABC transporter
LXX_RS10935	COG1172	Belongs to the binding-protein-dependent transport system permease family
LXX_RS11030	COG1278	Cold shock
LXX_RS11060	COG0697	spore germination
LXX_RS11150	COG2026	Addiction module toxin, RelE StbE family
LXX_RS11220	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LXX_RS11240	COG0151	Belongs to the GarS family
LXX_RS11245	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
LXX_RS11295	COG1063	alcohol dehydrogenase
LXX_RS11310	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LXX_RS11315	COG0047	phosphoribosylformylglycinamidine synthase activity
LXX_RS11330	COG1472	Belongs to the glycosyl hydrolase 3 family
LXX_RS11340	COG1609	Transcriptional regulator
LXX_RS11355	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LXX_RS11375	COG1309	transcriptional regulator
LXX_RS11385	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LXX_RS11390	COG0697	spore germination
LXX_RS11410	COG1215	transferase activity, transferring glycosyl groups
LXX_RS11425	COG1605	Chorismate mutase
LXX_RS11425	COG0287	Prephenate dehydrogenase
LXX_RS11435	COG1136	(ABC) transporter
LXX_RS11440	COG4552	Acetyltransferase involved in intracellular survival and related
LXX_RS11445	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LXX_RS11465	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LXX_RS11495	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LXX_RS11565	COG1609	Transcriptional regulator
LXX_RS11590	COG0542	response to heat
LXX_RS11630	COG2813	Specifically methylates the guanine in position
LXX_RS11645	COG0789	Transcriptional regulator
LXX_RS11650	COG0484	heat shock protein binding
LXX_RS11655	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LXX_RS11660	COG0443	Heat shock 70 kDa protein
LXX_RS11670	COG2357	RelA SpoT domain protein
LXX_RS11675	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
LXX_RS11685	COG0717	Belongs to the dCTP deaminase family
LXX_RS11765	COG0863	Belongs to the N(4) N(6)-methyltransferase family
LXX_RS11815	COG4695	Portal protein
LXX_RS11920	COG2188	Transcriptional regulator
LXX_RS11965	COG0673	inositol 2-dehydrogenase activity
LXX_RS12010	COG1278	Cold shock
LXX_RS12015	COG1230	cation diffusion facilitator family transporter
LXX_RS12030	COG4067	protein conserved in archaea
LXX_RS12030	COG0189	ligase activity
LXX_RS12050	COG2409	Drug exporters of the RND superfamily
LXX_RS12060	COG0494	nUDIX hydrolase
LXX_RS12065	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LXX_RS12225	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LXX_RS12240	COG0776	regulation of translation
LXX_RS12245	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LXX_RS12250	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LXX_RS12255	COG0227	Belongs to the bacterial ribosomal protein bL28 family
LXX_RS12270	COG3842	ATPase activity
LXX_RS12280	COG0508	dehydrogenase complex catalyzes the overall conversion of
LXX_RS12285	COG0022	dehydrogenase e1 component
LXX_RS12295	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LXX_RS12305	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LXX_RS12325	COG0305	Participates in initiation and elongation during chromosome replication
LXX_RS12330	COG0359	binds to the 23S rRNA
LXX_RS12335	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LXX_RS12345	COG0360	Binds together with S18 to 16S ribosomal RNA
LXX_RS12350	COG0617	tRNA 3'-terminal CCA addition
LXX_RS12365	COG0492	ferredoxin-NADP+ reductase activity
LXX_RS12370	COG3118	belongs to the thioredoxin family
LXX_RS12375	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LXX_RS12385	COG1475	DNA binding
LXX_RS12390	COG1192	Involved in chromosome partitioning
LXX_RS12395	COG0357	Ribosomal RNA small subunit methyltransferase G
LXX_RS12405	COG0706	membrane insertase activity
LXX_RS12410	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
LXX_RS12415	COG0594	ribonuclease P activity
LXX_RS12420	COG0230	Belongs to the bacterial ribosomal protein bL34 family
LXX_RS12455	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
LXX_RS12455	COG2755	lipolytic protein G-D-S-L family
LXX_RS12470	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LXX_RS12580	COG1120	ATPase activity
LXX_RS12585	COG1120	ATPase activity
LXX_RS12625	COG4585	Histidine kinase
LXX_RS12630	COG3876	Protein conserved in bacteria
LXX_RS12635	COG3876	Protein conserved in bacteria
LXX_RS12650	COG1181	Belongs to the D-alanine--D-alanine ligase family
LXX_RS12705	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LXX_RS12705	COG0512	Glutamine amidotransferase of anthranilate synthase
LXX_RS12715	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LXX_RS12745	COG2986	histidine ammonia-lyase
LXX_RS12765	COG2205	protein histidine kinase activity
LXX_RS12775	COG3842	ATPase activity
LXX_RS12860	COG4565	transcriptional regulatory protein
LXX_RS12865	COG3290	protein histidine kinase activity
LXX_RS12925	COG0671	phosphoesterase, PA-phosphatase related
LXX_RS12950	COG1674	ftsk spoiiie
LXX_RS12975	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
LXX_RS12995	COG1802	Transcriptional regulator
LXX_RS13020	COG0515	serine threonine protein kinase
LXX_RS13020	COG2815	serine threonine protein kinase
LXX_RS13035	COG1802	Transcriptional regulator