locus-tag	class	description
LMJF_01_0050	COG4770	biotin carboxylase activity
LMJF_01_0110	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LMJF_01_0180	COG0038	chloride channel
LMJF_01_0240	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LMJF_01_0450	COG1335	isochorismatase
LMJF_01_0470	COG1022	Amp-dependent synthetase and ligase
LMJF_01_0470	COG3320	Male sterility
LMJF_01_0500	COG1022	Amp-dependent synthetase and ligase
LMJF_01_0530	COG0318	PFAM AMP-dependent synthetase and ligase
LMJF_01_0650	COG0612	Peptidase, M16
LMJF_01_0710	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LMJF_01_0750	COG0515	serine threonine protein kinase
LMJF_02_0380	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
LMJF_02_0500	COG1929	Belongs to the glycerate kinase type-1 family
LMJF_02_0630	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LMJF_02_0710	COG0542	response to heat
LMJF_02_0740	COG0339	signal peptide processing
LMJF_03_0030	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LMJF_03_0040	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LMJF_03_0060	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LMJF_03_0100	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
LMJF_03_0160	COG0488	(ABC) transporter
LMJF_03_0200	COG1012	belongs to the aldehyde dehydrogenase family
LMJF_03_0210	COG2815	serine threonine protein kinase
LMJF_03_0210	COG0515	serine threonine protein kinase
LMJF_03_0380	COG1584	GPR1 FUN34 yaaH family protein
LMJF_03_0390	COG1584	GPR1 FUN34 yaaH family protein
LMJF_03_0400	COG1584	GPR1 FUN34 yaaH family protein
LMJF_03_0500	COG0306	phosphate transporter
LMJF_03_0540	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LMJF_03_0610	COG1703	isobutyryl-CoA mutase activity
LMJF_03_0690	COG4581	dead DEAH box helicase
LMJF_03_0710	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LMJF_03_0910	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LMJF_03_0930	COG1228	amidohydrolase
LMJF_04_0250	COG0564	pseudouridine synthase activity
LMJF_04_0310	COG1621	beta-fructofuranosidase activity
LMJF_04_0330	COG0557	exoribonuclease II activity
LMJF_04_0470	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LMJF_04_0780	COG0484	heat shock protein binding
LMJF_04_0820	COG0242	peptide deformylase activity
LMJF_04_0860	COG1841	ribosomal large subunit assembly
LMJF_04_0940	COG0484	heat shock protein binding
LMJF_04_0960	COG0563	adenylate kinase activity
LMJF_04_1130	COG1999	signal sequence binding
LMJF_04_1160	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
LMJF_04_1190	COG0617	tRNA 3'-terminal CCA addition
LMJF_04_1210	COG0515	serine threonine protein kinase
LMJF_04_1230	COG5277	cytoskeleton organization
LMJF_05_0030	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LMJF_05_0140	COG0513	Belongs to the DEAD box helicase family
LMJF_05_0200	COG1160	GTP binding
LMJF_05_0230	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LMJF_05_0230	COG4624	Iron only hydrogenase large subunit, C-terminal domain
LMJF_05_0310	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LMJF_05_0400	COG1196	nuclear chromosome segregation
LMJF_05_0460	COG1160	GTP binding
LMJF_05_0500	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LMJF_05_0510	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LMJF_05_0550	COG2815	serine threonine protein kinase
LMJF_05_0550	COG0515	serine threonine protein kinase
LMJF_05_0590	COG0513	Belongs to the DEAD box helicase family
LMJF_05_0830	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
LMJF_05_0980	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
LMJF_05_1060	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
LMJF_06_0080	COG0842	Transport permease protein
LMJF_06_0080	COG1131	(ABC) transporter
LMJF_06_0080	COG1716	ATPase activity
LMJF_06_0090	COG1716	ATPase activity
LMJF_06_0090	COG1131	(ABC) transporter
LMJF_06_0090	COG0842	Transport permease protein
LMJF_06_0100	COG1716	ATPase activity
LMJF_06_0100	COG0842	Transport permease protein
LMJF_06_0100	COG1131	(ABC) transporter
LMJF_06_0160	COG1078	dGTPase activity
LMJF_06_0290	COG0328	RNA-DNA hybrid ribonuclease activity
LMJF_06_0350	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LMJF_06_0460	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LMJF_06_0570	COG0089	rRNA binding
LMJF_06_0580	COG0089	rRNA binding
LMJF_06_0610	COG0288	reversible hydration of carbon dioxide
LMJF_06_0640	COG2815	serine threonine protein kinase
LMJF_06_0640	COG0515	serine threonine protein kinase
LMJF_06_0730	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LMJF_06_0860	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LMJF_06_0870	COG2264	protein methyltransferase activity
LMJF_06_0930	COG0446	pyridine nucleotide-disulphide oxidoreductase
LMJF_06_0930	COG1902	pentaerythritol trinitrate reductase activity
LMJF_06_0950	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LMJF_06_1240	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LMJF_07_0090	COG1410	methionine synthase
LMJF_07_0090	COG0646	methionine synthase
LMJF_07_0170	COG0515	serine threonine protein kinase
LMJF_07_0170	COG2815	serine threonine protein kinase
LMJF_07_0260	COG0460	homoserine dehydrogenase
LMJF_07_0430	COG2030	dehydratase
LMJF_07_0650	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LMJF_07_0680	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LMJF_07_0800	COG1053	succinate dehydrogenase
LMJF_07_0805	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LMJF_07_0880	COG0515	serine threonine protein kinase
LMJF_07_1020	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LMJF_07_1030	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LMJF_07_1050	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LMJF_07_1140	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LMJF_07_1140	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LMJF_08_0010	COG1196	nuclear chromosome segregation
LMJF_08_0080	COG0513	Belongs to the DEAD box helicase family
LMJF_08_0180	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LMJF_08_0230	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LMJF_08_0280	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LMJF_08_0290	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LMJF_08_0510	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LMJF_08_0530	COG0515	serine threonine protein kinase
LMJF_08_0650	COG0484	heat shock protein binding
LMJF_08_0930	COG2815	serine threonine protein kinase
LMJF_08_0930	COG0515	serine threonine protein kinase
LMJF_08_1090	COG0123	including yeast histone deacetylase and acetoin utilization protein
LMJF_08_1130	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LMJF_09_0050	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LMJF_09_0070	COG1643	Atp-dependent helicase
LMJF_09_0230	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LMJF_09_0360	COG0415	Belongs to the DNA photolyase family
LMJF_09_0400	COG2815	serine threonine protein kinase
LMJF_09_0400	COG0515	serine threonine protein kinase
LMJF_09_0410	COG0515	serine threonine protein kinase
LMJF_09_0410	COG2815	serine threonine protein kinase
LMJF_09_0590	COG0210	DNA helicase
LMJF_09_0600	COG3340	Belongs to the peptidase S51 family
LMJF_09_0830	COG0513	Belongs to the DEAD box helicase family
LMJF_09_1220	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LMJF_09_1460	COG2897	thiosulfate sulfurtransferase activity
LMJF_10_0030	COG0306	phosphate transporter
LMJF_10_0090	COG4221	oxidoreductase activity
LMJF_10_0140	COG0513	Belongs to the DEAD box helicase family
LMJF_10_0200	COG0515	serine threonine protein kinase
LMJF_10_0420	COG2376	Dihydroxyacetone kinase
LMJF_10_0510	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LMJF_10_0560	COG0604	alcohol dehydrogenase
LMJF_10_0600	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LMJF_10_0890	COG0545	Peptidyl-prolyl cis-trans isomerase
LMJF_10_1300	COG0306	phosphate transporter
LMJF_11_0030	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LMJF_11_0040	COG1136	(ABC) transporter
LMJF_11_0040	COG0577	efflux transmembrane transporter activity
LMJF_11_0050	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LMJF_11_0060	COG2815	serine threonine protein kinase
LMJF_11_0060	COG0515	serine threonine protein kinase
LMJF_11_0100	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LMJF_11_0110	COG2815	serine threonine protein kinase
LMJF_11_0110	COG0515	serine threonine protein kinase
LMJF_11_0130	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LMJF_11_0190	COG0513	Belongs to the DEAD box helicase family
LMJF_11_0210	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LMJF_11_0220	COG2154	pterin-4-alpha-carbinolamine dehydratase
LMJF_11_0250	COG0515	serine threonine protein kinase
LMJF_11_0320	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LMJF_11_0330	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LMJF_11_0590	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LMJF_11_0620	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LMJF_11_0630	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LMJF_11_0690	COG0666	response to abiotic stimulus
LMJF_11_0960	COG0049	tRNA binding
LMJF_11_0970	COG0049	tRNA binding
LMJF_11_1000	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LMJF_11_1000	COG0574	Belongs to the PEP-utilizing enzyme family
LMJF_11_1100	COG2124	cytochrome p450
LMJF_12_0030	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
LMJF_12_0210	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LMJF_12_0220	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LMJF_12_0250	COG0215	cysteine-tRNA ligase activity
LMJF_12_0260	COG1643	Atp-dependent helicase
LMJF_12_1130	COG1902	pentaerythritol trinitrate reductase activity
LMJF_12_1140	COG1902	pentaerythritol trinitrate reductase activity
LMJF_12_1270	COG2264	protein methyltransferase activity
LMJF_13_0020	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LMJF_13_0050	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LMJF_13_0090	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
LMJF_13_0720	COG1063	alcohol dehydrogenase
LMJF_13_0930	COG3306	glycosyltransferase involved in LPS biosynthesis
LMJF_13_0960	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LMJF_13_1140	COG0596	Alpha beta hydrolase
LMJF_13_1190	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LMJF_13_1520	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LMJF_13_1530	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LMJF_13_1630	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LMJF_13_1630	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LMJF_13_1640	COG0515	serine threonine protein kinase
LMJF_13_1680	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LMJF_14_0180	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
LMJF_14_0240	COG0537	adenosine 5'-monophosphoramidase activity
LMJF_14_0460	COG0626	cystathionine gamma-synthase activity
LMJF_14_0780	COG0261	This protein binds to 23S rRNA in the presence of protein L20
LMJF_14_0840	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LMJF_14_0920	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LMJF_14_0920	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LMJF_14_0920	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LMJF_14_0950	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LMJF_14_1160	COG0148	phosphopyruvate hydratase activity
LMJF_14_1190	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LMJF_14_1190	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LMJF_14_1320	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LMJF_14_1330	COG0484	heat shock protein binding
LMJF_14_1370	COG0180	Tryptophanyl-tRNA synthetase
LMJF_14_1410	COG0515	serine threonine protein kinase
LMJF_14_1410	COG2815	serine threonine protein kinase
LMJF_15_0050	COG2871	sodium ion transport
LMJF_15_0090	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LMJF_15_0130	COG0513	Belongs to the DEAD box helicase family
LMJF_15_0300	COG4574	serine-type endopeptidase inhibitor activity
LMJF_15_0360	COG0564	pseudouridine synthase activity
LMJF_15_0390	COG0252	asparaginase activity
LMJF_15_0500	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LMJF_15_0510	COG4574	serine-type endopeptidase inhibitor activity
LMJF_15_0520	COG4574	serine-type endopeptidase inhibitor activity
LMJF_15_0760	COG1131	(ABC) transporter
LMJF_15_0880	COG0483	inositol monophosphate 1-phosphatase activity
LMJF_15_0890	COG1716	ATPase activity
LMJF_15_0890	COG1131	(ABC) transporter
LMJF_15_0890	COG0842	Transport permease protein
LMJF_15_0990	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LMJF_15_1010	COG2902	Dehydrogenase
LMJF_15_1020	COG0142	geranyltranstransferase activity
LMJF_15_1040	COG0450	alkyl hydroperoxide reductase
LMJF_15_1060	COG0450	alkyl hydroperoxide reductase
LMJF_15_1080	COG0450	alkyl hydroperoxide reductase
LMJF_15_1100	COG0450	alkyl hydroperoxide reductase
LMJF_15_1120	COG0450	alkyl hydroperoxide reductase
LMJF_15_1140	COG0450	alkyl hydroperoxide reductase
LMJF_15_1160	COG0450	alkyl hydroperoxide reductase
LMJF_15_1200	COG0515	serine threonine protein kinase
LMJF_15_1200	COG2815	serine threonine protein kinase
LMJF_15_1220	COG0484	heat shock protein binding
LMJF_15_1290	COG0187	DNA topoisomerase II activity
LMJF_15_1310	COG0598	Magnesium transport protein CorA
LMJF_15_1420	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LMJF_16_0030	COG2264	protein methyltransferase activity
LMJF_16_0050	COG0513	Belongs to the DEAD box helicase family
LMJF_16_0300	COG0515	serine threonine protein kinase
LMJF_16_0530	COG0167	dihydroorotate dehydrogenase activity
LMJF_16_0550	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LMJF_16_0550	COG0284	orotidine-5'-phosphate decarboxylase activity
LMJF_16_0580	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LMJF_16_0590	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LMJF_16_0680	COG0708	Exodeoxyribonuclease III
LMJF_16_0760	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LMJF_16_0950	COG0438	transferase activity, transferring glycosyl groups
LMJF_16_0960	COG2226	methyltransferase
LMJF_16_1000	COG0438	transferase activity, transferring glycosyl groups
LMJF_16_1005	COG0438	transferase activity, transferring glycosyl groups
LMJF_16_1010	COG0438	transferase activity, transferring glycosyl groups
LMJF_16_1015	COG0438	transferase activity, transferring glycosyl groups
LMJF_16_1020	COG0438	transferase activity, transferring glycosyl groups
LMJF_16_1030	COG0438	transferase activity, transferring glycosyl groups
LMJF_16_1040	COG0438	transferase activity, transferring glycosyl groups
LMJF_16_1050	COG0438	transferase activity, transferring glycosyl groups
LMJF_16_1060	COG0438	transferase activity, transferring glycosyl groups
LMJF_16_1130	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LMJF_16_1130	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LMJF_16_1200	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LMJF_16_1350	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LMJF_16_1360	COG0154	amidase activity
LMJF_16_1540	COG0417	DNA replication proofreading
LMJF_17_0060	COG2815	serine threonine protein kinase
LMJF_17_0060	COG0515	serine threonine protein kinase
LMJF_17_0140	COG2195	Cleaves the N-terminal amino acid of tripeptides
LMJF_17_0250	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LMJF_17_0270	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
LMJF_17_0350	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LMJF_17_0490	COG0515	serine threonine protein kinase
LMJF_17_0580	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
LMJF_17_0600	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LMJF_17_0725	COG0517	IMP dehydrogenase activity
LMJF_17_0725	COG0516	GMP reductase activity
LMJF_17_1040	COG1073	alpha beta
LMJF_17_1390	COG0483	inositol monophosphate 1-phosphatase activity
LMJF_17_1460	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
LMJF_18_0080	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LMJF_18_0140	COG1253	flavin adenine dinucleotide binding
LMJF_18_0270	COG2815	serine threonine protein kinase
LMJF_18_0270	COG0515	serine threonine protein kinase
LMJF_18_0330	COG0484	heat shock protein binding
LMJF_18_0480	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LMJF_18_0510	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LMJF_18_0580	COG1250	3-hydroxyacyl-CoA dehydrogenase
LMJF_18_0580	COG1024	Enoyl-CoA hydratase
LMJF_18_0610	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LMJF_18_0620	COG0081	regulation of translation
LMJF_18_0640	COG0515	serine threonine protein kinase
LMJF_18_0740	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LMJF_18_0880	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LMJF_18_1110	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LMJF_18_1110	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
LMJF_18_1210	COG0442	prolyl-tRNA aminoacylation
LMJF_18_1220	COG0442	prolyl-tRNA aminoacylation
LMJF_18_1370	COG0443	Heat shock 70 kDa protein
LMJF_18_1380	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LMJF_18_1430	COG0484	heat shock protein binding
LMJF_18_1480	COG1034	ATP synthesis coupled electron transport
LMJF_18_1490	COG0484	heat shock protein binding
LMJF_18_1510	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LMJF_18_1520	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LMJF_19_0060	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LMJF_19_0080	COG0484	heat shock protein binding
LMJF_19_0140	COG2815	serine threonine protein kinase
LMJF_19_0140	COG0515	serine threonine protein kinase
LMJF_19_0180	COG0515	serine threonine protein kinase
LMJF_19_0180	COG2815	serine threonine protein kinase
LMJF_19_0310	COG2119	membrane
LMJF_19_0350	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LMJF_19_0590	COG0515	serine threonine protein kinase
LMJF_19_0710	COG0039	L-malate dehydrogenase activity
LMJF_19_0730	COG2226	methyltransferase
LMJF_19_0800	COG0488	(ABC) transporter
LMJF_19_0985	COG0318	PFAM AMP-dependent synthetase and ligase
LMJF_19_0995	COG0318	PFAM AMP-dependent synthetase and ligase
LMJF_19_1005	COG0318	PFAM AMP-dependent synthetase and ligase
LMJF_19_1020	COG0101	tRNA pseudouridine synthase activity
LMJF_19_1040	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LMJF_19_1040	COG0072	phenylalanine-tRNA ligase activity
LMJF_19_1380	COG1230	cation diffusion facilitator family transporter
LMJF_19_1530	COG0545	Peptidyl-prolyl cis-trans isomerase
LMJF_19_1590	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LMJF_20_0090	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LMJF_20_0100	COG0126	phosphoglycerate kinase activity
LMJF_20_0110	COG0126	phosphoglycerate kinase activity
LMJF_20_0260	COG0714	Associated with various cellular activities
LMJF_20_0550	COG0484	heat shock protein binding
LMJF_20_0560	COG0504	CTP synthase activity
LMJF_20_0810	COG1222	aaa ATPase
LMJF_20_0840	COG1999	signal sequence binding
LMJF_20_0960	COG0515	serine threonine protein kinase
LMJF_20_1010	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LMJF_20_1130	COG0484	heat shock protein binding
LMJF_20_1330	COG0515	serine threonine protein kinase
LMJF_20_1650	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LMJF_21_0125	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LMJF_21_0125	COG1754	DNA topoisomerase type I activity
LMJF_21_0150	COG2815	serine threonine protein kinase
LMJF_21_0150	COG0515	serine threonine protein kinase
LMJF_21_0270	COG0515	serine threonine protein kinase
LMJF_21_0270	COG2815	serine threonine protein kinase
LMJF_21_0490	COG0484	heat shock protein binding
LMJF_21_0550	COG0022	dehydrogenase e1 component
LMJF_21_0550	COG0508	dehydrogenase complex catalyzes the overall conversion of
LMJF_21_0630	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LMJF_21_0640	COG0033	Phosphoglucomutase
LMJF_21_0660	COG0489	protein tyrosine kinase activity
LMJF_21_0680	COG0123	including yeast histone deacetylase and acetoin utilization protein
LMJF_21_0710	COG1121	(ABC) transporter
LMJF_21_0740	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LMJF_21_0810	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LMJF_21_0823	COG0515	serine threonine protein kinase
LMJF_21_0823	COG2815	serine threonine protein kinase
LMJF_21_0840	COG0024	Methionine aminopeptidase
LMJF_21_0850	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
LMJF_21_0880	COG1136	(ABC) transporter
LMJF_21_0885	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LMJF_21_0895	COG0017	Asparaginyl-tRNA synthetase
LMJF_21_1050	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LMJF_21_1090	COG0459	protein refolding
LMJF_21_1190	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LMJF_21_1250	COG0563	adenylate kinase activity
LMJF_21_1330	COG1196	nuclear chromosome segregation
LMJF_21_1430	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LMJF_21_1550	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LMJF_21_1565	COG2815	serine threonine protein kinase
LMJF_21_1565	COG0515	serine threonine protein kinase
LMJF_21_1650	COG0515	serine threonine protein kinase
LMJF_21_1770	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LMJF_22_0030	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LMJF_22_0250	COG2365	Tyrosine phosphatase family
LMJF_22_0420	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LMJF_22_0460	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LMJF_22_0470	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LMJF_22_0470	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LMJF_22_0490	COG2815	serine threonine protein kinase
LMJF_22_0490	COG0515	serine threonine protein kinase
LMJF_22_0530	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LMJF_22_0570	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LMJF_22_0720	COG0218	Necessary for normal cell division and for the maintenance of normal septation
LMJF_22_0770	COG2871	sodium ion transport
LMJF_22_0820	COG0218	Necessary for normal cell division and for the maintenance of normal septation
LMJF_22_0930	COG1222	aaa ATPase
LMJF_22_0940	COG1222	aaa ATPase
LMJF_22_0950	COG2815	serine threonine protein kinase
LMJF_22_0950	COG0515	serine threonine protein kinase
LMJF_22_1240	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LMJF_22_1450	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LMJF_22_1500	COG1643	Atp-dependent helicase
LMJF_22_1530	COG0237	dephospho-CoA kinase activity
LMJF_22_1540	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LMJF_23_0040	COG0450	alkyl hydroperoxide reductase
LMJF_23_0050	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LMJF_23_0070	COG0010	Belongs to the arginase family
LMJF_23_0110	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LMJF_23_0210	COG1132	(ABC) transporter
LMJF_23_0220	COG1132	(ABC) transporter
LMJF_23_0250	COG1132	(ABC) transporter
LMJF_23_0260	COG0137	argininosuccinate synthase activity
LMJF_23_0300	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LMJF_23_0380	COG1716	ATPase activity
LMJF_23_0380	COG1131	(ABC) transporter
LMJF_23_0380	COG0842	Transport permease protein
LMJF_23_0460	COG0754	glutathionylspermidine amidase activity
LMJF_23_0530	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
LMJF_23_0540	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LMJF_23_0550	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LMJF_23_0670	COG0673	inositol 2-dehydrogenase activity
LMJF_23_0710	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LMJF_23_0740	COG0218	Necessary for normal cell division and for the maintenance of normal septation
LMJF_23_0810	COG0277	FAD linked oxidase domain protein
LMJF_23_0830	COG0025	NhaP-type Na H and K H
LMJF_23_0950	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LMJF_23_1200	COG0275	rRNA processing
LMJF_23_1210	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LMJF_23_1220	COG0459	protein refolding
LMJF_23_1330	COG0417	DNA replication proofreading
LMJF_23_1410	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LMJF_23_1460	COG1956	GAF domain-containing protein
LMJF_23_1480	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LMJF_23_1510	COG1269	ATP hydrolysis coupled proton transport
LMJF_23_1600	COG0673	inositol 2-dehydrogenase activity
LMJF_23_1660	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LMJF_24_0040	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LMJF_24_0180	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LMJF_24_0230	COG0515	serine threonine protein kinase
LMJF_24_0230	COG2815	serine threonine protein kinase
LMJF_24_0250	COG0513	Belongs to the DEAD box helicase family
LMJF_24_0320	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
LMJF_24_0320	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
LMJF_24_0370	COG1448	Aminotransferase
LMJF_24_0460	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LMJF_24_0520	COG0484	heat shock protein binding
LMJF_24_0610	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LMJF_24_0630	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LMJF_24_0670	COG0515	serine threonine protein kinase
LMJF_24_0680	COG2814	Major facilitator Superfamily
LMJF_24_0730	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LMJF_24_0760	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LMJF_24_0770	COG0281	malic enzyme
LMJF_24_0850	COG0149	triose-phosphate isomerase activity
LMJF_24_1050	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LMJF_24_1100	COG1643	Atp-dependent helicase
LMJF_24_1315	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LMJF_24_1370	COG0123	including yeast histone deacetylase and acetoin utilization protein
LMJF_24_1420	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LMJF_24_1440	COG2301	Belongs to the HpcH HpaI aldolase family
LMJF_24_1730	COG0515	serine threonine protein kinase
LMJF_24_1730	COG2815	serine threonine protein kinase
LMJF_24_1740	COG0354	folic acid binding
LMJF_24_1780	COG0318	PFAM AMP-dependent synthetase and ligase
LMJF_24_1820	COG1028	Short-chain dehydrogenase reductase Sdr
LMJF_24_1840	COG0400	carboxylic ester hydrolase activity
LMJF_24_2060	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LMJF_24_2160	COG0584	glycerophosphoryl diester phosphodiesterase
LMJF_24_2320	COG0515	serine threonine protein kinase
LMJF_24_2320	COG2815	serine threonine protein kinase
LMJF_25_0130	COG1217	gtp-binding protein TYPA
LMJF_25_0450	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LMJF_25_0530	COG1132	(ABC) transporter
LMJF_25_0620	COG0085	RNA polymerase activity
LMJF_25_0740	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LMJF_25_0740	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LMJF_25_0910	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LMJF_25_1020	COG2084	Dehydrogenase
LMJF_25_1050	COG1965	Belongs to the frataxin family
LMJF_25_1120	COG1012	belongs to the aldehyde dehydrogenase family
LMJF_25_1450	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LMJF_25_1500	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LMJF_25_1500	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
LMJF_25_1560	COG2815	serine threonine protein kinase
LMJF_25_1560	COG0515	serine threonine protein kinase
LMJF_25_1690	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
LMJF_25_1710	COG0508	dehydrogenase complex catalyzes the overall conversion of
LMJF_25_1710	COG0022	dehydrogenase e1 component
LMJF_25_1960	COG1254	Belongs to the acylphosphatase family
LMJF_25_1990	COG0515	serine threonine protein kinase
LMJF_25_2080	COG0481	GTPase activity
LMJF_25_2130	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LMJF_25_2140	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LMJF_25_2190	COG0484	heat shock protein binding
LMJF_25_2340	COG0515	serine threonine protein kinase
LMJF_25_2370	COG0563	adenylate kinase activity
LMJF_26_0020	COG0346	lactoylglutathione lyase activity
LMJF_26_0030	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LMJF_26_0030	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LMJF_26_0140	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LMJF_26_0210	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LMJF_26_0270	COG1160	GTP binding
LMJF_26_0300	COG0308	aminopeptidase N
LMJF_26_0320	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LMJF_26_0420	COG0101	tRNA pseudouridine synthase activity
LMJF_26_0430	COG0489	protein tyrosine kinase activity
LMJF_26_0460	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LMJF_26_0580	COG2967	ApaG domain
LMJF_26_0620	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LMJF_26_0640	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LMJF_26_0800	COG0386	Belongs to the glutathione peroxidase family
LMJF_26_0810	COG0386	Belongs to the glutathione peroxidase family
LMJF_26_0820	COG0386	Belongs to the glutathione peroxidase family
LMJF_26_0900	COG0443	Heat shock 70 kDa protein
LMJF_26_0940	COG0484	heat shock protein binding
LMJF_26_1160	COG0564	pseudouridine synthase activity
LMJF_26_1210	COG0656	L-ascorbic acid biosynthetic process
LMJF_26_1240	COG0443	Heat shock 70 kDa protein
LMJF_26_1270	COG0484	heat shock protein binding
LMJF_26_1370	COG0218	Necessary for normal cell division and for the maintenance of normal septation
LMJF_26_1410	COG0484	heat shock protein binding
LMJF_26_1550	COG1250	3-hydroxyacyl-CoA dehydrogenase
LMJF_26_1550	COG1024	Enoyl-CoA hydratase
LMJF_26_1570	COG0339	signal peptide processing
LMJF_26_1620	COG0575	Belongs to the CDS family
LMJF_26_1940	COG0824	Thioesterase
LMJF_26_1970	COG1999	signal sequence binding
LMJF_26_2230	COG1088	dTDP-glucose 4,6-dehydratase activity
LMJF_26_2240	COG3844	kynureninase activity
LMJF_26_2330	COG0255	Belongs to the universal ribosomal protein uL29 family
LMJF_26_2340	COG0255	Belongs to the universal ribosomal protein uL29 family
LMJF_26_2560	COG1181	Belongs to the D-alanine--D-alanine ligase family
LMJF_26_2610	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LMJF_26_2700	COG0363	glucosamine-6-phosphate deaminase activity
LMJF_26_2710	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LMJF_27_0030	COG0343	queuine tRNA-ribosyltransferase activity
LMJF_27_0050	COG0513	Belongs to the DEAD box helicase family
LMJF_27_0100	COG4991	sh3 domain protein
LMJF_27_0100	COG3064	Membrane
LMJF_27_0100	COG0515	serine threonine protein kinase
LMJF_27_0290	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LMJF_27_0300	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LMJF_27_0300	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LMJF_27_0360	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LMJF_27_0410	COG0484	heat shock protein binding
LMJF_27_0420	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LMJF_27_0550	COG2255	four-way junction helicase activity
LMJF_27_0740	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LMJF_27_0790	COG0534	Mate efflux family protein
LMJF_27_0930	COG1960	acyl-CoA dehydrogenase activity
LMJF_27_0970	COG1131	(ABC) transporter
LMJF_27_0980	COG1131	(ABC) transporter
LMJF_27_1070	COG1222	aaa ATPase
LMJF_27_1260	COG0459	protein refolding
LMJF_27_1310	COG0018	arginyl-trna synthetase
LMJF_27_1370	COG2815	serine threonine protein kinase
LMJF_27_1370	COG0515	serine threonine protein kinase
LMJF_27_1670	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LMJF_27_1750	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LMJF_27_1805	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
LMJF_27_1810	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
LMJF_27_1830	COG0012	GTP binding
LMJF_27_1870	COG0754	glutathionylspermidine amidase activity
LMJF_27_1980	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
LMJF_27_2020	COG0277	FAD linked oxidase domain protein
LMJF_27_2030	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LMJF_27_2400	COG0484	heat shock protein binding
LMJF_27_2410	COG0656	L-ascorbic acid biosynthetic process
LMJF_27_2440	COG1028	Short-chain dehydrogenase reductase Sdr
LMJF_27_2630	COG0542	response to heat
LMJF_27_2660	COG0339	signal peptide processing
LMJF_28_0240	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LMJF_28_0330	COG0557	exoribonuclease II activity
LMJF_28_0380	COG3268	Saccharopine dehydrogenase
LMJF_28_0400	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LMJF_28_0450	COG0557	exoribonuclease II activity
LMJF_28_0480	COG3338	carbonate dehydratase activity
LMJF_28_0490	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LMJF_28_0520	COG2815	serine threonine protein kinase
LMJF_28_0520	COG0515	serine threonine protein kinase
LMJF_28_0530	COG0419	ATPase involved in DNA repair
LMJF_28_0760	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LMJF_28_0890	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LMJF_28_0890	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LMJF_28_0960	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LMJF_28_1010	COG0051	transcription antitermination factor activity, RNA binding
LMJF_28_1030	COG0051	transcription antitermination factor activity, RNA binding
LMJF_28_1095	COG3265	gluconokinase activity
LMJF_28_1150	COG0318	PFAM AMP-dependent synthetase and ligase
LMJF_28_1200	COG0443	Heat shock 70 kDa protein
LMJF_28_1270	COG0484	heat shock protein binding
LMJF_28_1280	COG3186	Phenylalanine-4-hydroxylase
LMJF_28_1310	COG0513	Belongs to the DEAD box helicase family
LMJF_28_1320	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
LMJF_28_1340	COG0561	phosphatase activity
LMJF_28_1350	COG0561	phosphatase activity
LMJF_28_1360	COG0561	phosphatase activity
LMJF_28_1370	COG0561	phosphatase activity
LMJF_28_1380	COG0561	phosphatase activity
LMJF_28_1420	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LMJF_28_1430	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LMJF_28_1460	COG1222	aaa ATPase
LMJF_28_1530	COG0513	Belongs to the DEAD box helicase family
LMJF_28_1570	COG0596	Alpha beta hydrolase
LMJF_28_1620	COG0585	pseudouridine synthase activity
LMJF_28_1740	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LMJF_28_1780	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LMJF_28_1790	COG1222	aaa ATPase
LMJF_28_1830	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LMJF_28_1960	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LMJF_28_1970	COG0698	ribose 5-phosphate isomerase
LMJF_28_2000	COG2815	serine threonine protein kinase
LMJF_28_2000	COG0515	serine threonine protein kinase
LMJF_28_2070	COG0009	L-threonylcarbamoyladenylate synthase
LMJF_28_2280	COG0187	DNA topoisomerase II activity
LMJF_28_2370	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LMJF_28_2470	COG0489	protein tyrosine kinase activity
LMJF_28_2510	COG1960	acyl-CoA dehydrogenase activity
LMJF_28_2530	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LMJF_28_2640	COG0315	cyclic pyranopterin monophosphate synthase activity
LMJF_28_2660	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LMJF_28_2680	COG1612	heme a metabolic process
LMJF_28_2740	COG2319	Wd-40 repeat
LMJF_28_2750	COG2319	Wd-40 repeat
LMJF_28_2770	COG0443	Heat shock 70 kDa protein
LMJF_28_2780	COG0443	Heat shock 70 kDa protein
LMJF_28_2820	COG0443	Heat shock 70 kDa protein
LMJF_28_2860	COG0039	L-malate dehydrogenase activity
LMJF_28_2910	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LMJF_28_3005	COG1247	-acetyltransferase
LMJF_29_0060	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LMJF_29_0200	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LMJF_29_0280	COG0277	FAD linked oxidase domain protein
LMJF_29_0370	COG0515	serine threonine protein kinase
LMJF_29_0370	COG2815	serine threonine protein kinase
LMJF_29_0540	COG2176	DNA-directed DNA polymerase activity
LMJF_29_0620	COG1131	(ABC) transporter
LMJF_29_0720	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LMJF_29_0760	COG0326	Molecular chaperone. Has ATPase activity
LMJF_29_0867	COG0402	S-adenosylhomocysteine deaminase activity
LMJF_29_1340	COG0724	RNA recognition motif
LMJF_29_1570	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LMJF_29_1640	COG1136	(ABC) transporter
LMJF_29_1710	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LMJF_29_1830	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LMJF_29_1960	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
LMJF_29_1960	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
LMJF_29_2020	COG0515	serine threonine protein kinase
LMJF_29_2020	COG2815	serine threonine protein kinase
LMJF_29_2150	COG0515	serine threonine protein kinase
LMJF_29_2310	COG1024	Enoyl-CoA hydratase
LMJF_29_2320	COG0515	serine threonine protein kinase
LMJF_29_2360	COG1362	aminopeptidase activity
LMJF_29_2490	COG0515	serine threonine protein kinase
LMJF_29_2540	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LMJF_29_2540	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
LMJF_29_2670	COG2815	serine threonine protein kinase
LMJF_29_2670	COG0515	serine threonine protein kinase
LMJF_30_0020	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LMJF_30_0120	COG0277	FAD linked oxidase domain protein
LMJF_30_0130	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LMJF_30_0210	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LMJF_30_0460	COG0017	Asparaginyl-tRNA synthetase
LMJF_30_0540	COG0724	RNA recognition motif
LMJF_30_0630	COG0124	histidyl-tRNA synthetase
LMJF_30_0730	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LMJF_30_0735	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LMJF_30_0800	COG0515	serine threonine protein kinase
LMJF_30_0800	COG2815	serine threonine protein kinase
LMJF_30_0880	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LMJF_30_1000	COG2815	serine threonine protein kinase
LMJF_30_1000	COG0515	serine threonine protein kinase
LMJF_30_1030	COG0484	heat shock protein binding
LMJF_30_1250	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
LMJF_30_1300	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LMJF_30_1330	COG0488	(ABC) transporter
LMJF_30_1520	COG0564	pseudouridine synthase activity
LMJF_30_1540	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LMJF_30_1550	COG0101	tRNA pseudouridine synthase activity
LMJF_30_1700	COG0542	response to heat
LMJF_30_1790	COG0484	heat shock protein binding
LMJF_30_1800	COG0343	queuine tRNA-ribosyltransferase activity
LMJF_30_1930	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LMJF_30_1940	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LMJF_30_1960	COG0564	pseudouridine synthase activity
LMJF_30_2290	COG0514	ATP-dependent DNA helicase (RecQ)
LMJF_30_2350	COG1104	cysteine desulfurase activity
LMJF_30_2370	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LMJF_30_2460	COG0443	Heat shock 70 kDa protein
LMJF_30_2470	COG0443	Heat shock 70 kDa protein
LMJF_30_2480	COG0443	Heat shock 70 kDa protein
LMJF_30_2490	COG0443	Heat shock 70 kDa protein
LMJF_30_2540	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LMJF_30_2550	COG0443	Heat shock 70 kDa protein
LMJF_30_2600	COG2759	Belongs to the formate--tetrahydrofolate ligase family
LMJF_30_2630	COG2255	four-way junction helicase activity
LMJF_30_2910	COG0515	serine threonine protein kinase
LMJF_30_2970	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LMJF_30_2980	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LMJF_30_3050	COG0515	serine threonine protein kinase
LMJF_30_3050	COG2815	serine threonine protein kinase
LMJF_30_3080	COG0083	homoserine kinase activity
LMJF_30_3130	COG0525	valine-tRNA ligase activity
LMJF_30_3240	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LMJF_30_3250	COG1643	Atp-dependent helicase
LMJF_30_3340	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LMJF_30_3380	COG0126	phosphoglycerate kinase activity
LMJF_30_3440	COG1793	dna ligase
LMJF_30_3470	COG0515	serine threonine protein kinase
LMJF_30_3470	COG2815	serine threonine protein kinase
LMJF_30_3550	COG2124	cytochrome p450
LMJF_30_3580	COG2815	serine threonine protein kinase
LMJF_30_3580	COG0515	serine threonine protein kinase
LMJF_30_3590	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LMJF_31_0010	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LMJF_31_0050	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LMJF_31_0160	COG0085	RNA polymerase activity
LMJF_31_0250	COG1643	Atp-dependent helicase
LMJF_31_0510	COG0484	heat shock protein binding
LMJF_31_0540	COG4178	(ABC) transporter
LMJF_31_0650	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
LMJF_31_0700	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LMJF_31_1070	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
LMJF_31_1070	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
LMJF_31_1130	COG1473	amidohydrolase
LMJF_31_1140	COG2267	carboxylic ester hydrolase activity
LMJF_31_1270	COG1132	(ABC) transporter
LMJF_31_1280	COG1132	(ABC) transporter
LMJF_31_1290	COG1132	(ABC) transporter
LMJF_31_1340	COG1278	Cold shock
LMJF_31_1620	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
LMJF_31_1640	COG0183	Belongs to the thiolase family
LMJF_31_2150	COG0656	L-ascorbic acid biosynthetic process
LMJF_31_2250	COG1024	Enoyl-CoA hydratase
LMJF_31_2320	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LMJF_31_2330	COG1250	3-hydroxyacyl-CoA dehydrogenase
LMJF_31_2330	COG1024	Enoyl-CoA hydratase
LMJF_31_2480	COG0633	Ferredoxin
LMJF_31_2490	COG0633	Ferredoxin
LMJF_31_2510	COG0633	Ferredoxin
LMJF_31_2610	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LMJF_31_2620	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LMJF_31_2640	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LMJF_31_2650	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LMJF_31_2810	COG1185	polyribonucleotide nucleotidyltransferase activity
LMJF_31_2850	COG0222	ribosome binding
LMJF_31_2860	COG0515	serine threonine protein kinase
LMJF_31_2860	COG2815	serine threonine protein kinase
LMJF_31_2880	COG0656	L-ascorbic acid biosynthetic process
LMJF_31_2960	COG0515	serine threonine protein kinase
LMJF_31_2970	COG0439	Biotin carboxylase
LMJF_31_3090	COG1025	Belongs to the peptidase M16 family
LMJF_31_3130	COG4770	biotin carboxylase activity
LMJF_31_3160	COG2815	serine threonine protein kinase
LMJF_31_3160	COG0515	serine threonine protein kinase
LMJF_32_0120	COG0515	serine threonine protein kinase
LMJF_32_0260	COG2815	serine threonine protein kinase
LMJF_32_0260	COG0515	serine threonine protein kinase
LMJF_32_0400	COG0513	Belongs to the DEAD box helicase family
LMJF_32_0430	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LMJF_32_0450	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LMJF_32_0460	COG0656	L-ascorbic acid biosynthetic process
LMJF_32_0570	COG0513	Belongs to the DEAD box helicase family
LMJF_32_0780	COG2815	serine threonine protein kinase
LMJF_32_0780	COG0515	serine threonine protein kinase
LMJF_32_0890	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
LMJF_32_0890	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
LMJF_32_1000	COG0459	protein refolding
LMJF_32_1300	COG0242	peptide deformylase activity
LMJF_32_1350	COG3475	LICD family
LMJF_32_1360	COG0563	adenylate kinase activity
LMJF_32_1500	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LMJF_32_1530	COG0494	nUDIX hydrolase
LMJF_32_1670	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LMJF_32_1810	COG0515	serine threonine protein kinase
LMJF_32_1810	COG2815	serine threonine protein kinase
LMJF_32_1820	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LMJF_32_1830	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LMJF_32_1850	COG0459	protein refolding
LMJF_32_1940	COG0484	heat shock protein binding
LMJF_32_2080	COG0590	tRNA wobble adenosine to inosine editing
LMJF_32_2090	COG2890	protein-(glutamine-N5) methyltransferase activity
LMJF_32_2200	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LMJF_32_2230	COG0513	Belongs to the DEAD box helicase family
LMJF_32_2240	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LMJF_32_2290	COG0671	phosphoesterase, PA-phosphatase related
LMJF_32_2370	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LMJF_32_2380	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LMJF_32_2540	COG1078	dGTPase activity
LMJF_32_2630	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LMJF_32_2640	COG0626	cystathionine gamma-synthase activity
LMJF_32_2870	COG4589	Belongs to the CDS family
LMJF_32_2950	COG0105	UTP biosynthetic process
LMJF_32_3020	COG0218	Necessary for normal cell division and for the maintenance of normal septation
LMJF_32_3030	COG0484	heat shock protein binding
LMJF_32_3080	COG5265	(ABC) transporter
LMJF_32_3110	COG0012	GTP binding
LMJF_32_3140	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LMJF_32_3250	COG2815	serine threonine protein kinase
LMJF_32_3250	COG0515	serine threonine protein kinase
LMJF_32_3270	COG0459	protein refolding
LMJF_32_3300	COG0484	heat shock protein binding
LMJF_32_3310	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LMJF_32_3380	COG0585	pseudouridine synthase activity
LMJF_32_3680	COG1024	Enoyl-CoA hydratase
LMJF_32_3900	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LMJF_33_0310	COG0488	(ABC) transporter
LMJF_33_0312	COG0326	Molecular chaperone. Has ATPase activity
LMJF_33_0314	COG0326	Molecular chaperone. Has ATPase activity
LMJF_33_0316	COG0326	Molecular chaperone. Has ATPase activity
LMJF_33_0318	COG0326	Molecular chaperone. Has ATPase activity
LMJF_33_0320	COG0326	Molecular chaperone. Has ATPase activity
LMJF_33_0323	COG0326	Molecular chaperone. Has ATPase activity
LMJF_33_0326	COG0326	Molecular chaperone. Has ATPase activity
LMJF_33_0330	COG0326	Molecular chaperone. Has ATPase activity
LMJF_33_0333	COG0326	Molecular chaperone. Has ATPase activity
LMJF_33_0336	COG0326	Molecular chaperone. Has ATPase activity
LMJF_33_0340	COG0326	Molecular chaperone. Has ATPase activity
LMJF_33_0343	COG0326	Molecular chaperone. Has ATPase activity
LMJF_33_0346	COG0326	Molecular chaperone. Has ATPase activity
LMJF_33_0350	COG0326	Molecular chaperone. Has ATPase activity
LMJF_33_0355	COG0326	Molecular chaperone. Has ATPase activity
LMJF_33_0360	COG0326	Molecular chaperone. Has ATPase activity
LMJF_33_0365	COG0326	Molecular chaperone. Has ATPase activity
LMJF_33_0410	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LMJF_33_0470	COG0415	Belongs to the DNA photolyase family
LMJF_33_0560	COG1690	Belongs to the RtcB family
LMJF_33_0830	COG0446	pyridine nucleotide-disulphide oxidoreductase
LMJF_33_0830	COG1902	pentaerythritol trinitrate reductase activity
LMJF_33_0900	COG0484	heat shock protein binding
LMJF_33_0960	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LMJF_33_1010	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LMJF_33_1090	COG0194	GDP metabolic process
LMJF_33_1200	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LMJF_33_1300	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LMJF_33_1330	COG0436	Aminotransferase
LMJF_33_1380	COG0515	serine threonine protein kinase
LMJF_33_1400	COG0515	serine threonine protein kinase
LMJF_33_1570	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LMJF_33_1590	COG0300	oxidoreductase activity
LMJF_33_1630	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LMJF_33_1670	COG0438	transferase activity, transferring glycosyl groups
LMJF_33_1680	COG0301	tRNA thio-modification
LMJF_33_1700	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LMJF_33_1830	COG4991	sh3 domain protein
LMJF_33_1830	COG3064	Membrane
LMJF_33_1830	COG0515	serine threonine protein kinase
LMJF_33_1860	COG4178	(ABC) transporter
LMJF_33_1930	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LMJF_33_1980	COG0515	serine threonine protein kinase
LMJF_33_2070	COG2815	serine threonine protein kinase
LMJF_33_2070	COG0515	serine threonine protein kinase
LMJF_33_2290	COG2815	serine threonine protein kinase
LMJF_33_2290	COG0515	serine threonine protein kinase
LMJF_33_2300	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LMJF_33_2390	COG0326	Molecular chaperone. Has ATPase activity
LMJF_33_2400	COG1160	GTP binding
LMJF_33_2540	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
LMJF_33_2550	COG0538	isocitrate dehydrogenase activity
LMJF_33_2570	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LMJF_33_2600	COG1250	3-hydroxyacyl-CoA dehydrogenase