locus-tag	class	description
LB4E_RS00010	COG0592	DNA-directed DNA polymerase activity
LB4E_RS00025	COG0187	DNA topoisomerase II activity
LB4E_RS00095	COG0009	L-threonylcarbamoyladenylate synthase
LB4E_RS00145	COG0483	inositol monophosphate 1-phosphatase activity
LB4E_RS00160	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LB4E_RS00165	COG0802	atpase or kinase
LB4E_RS00175	COG0557	exoribonuclease II activity
LB4E_RS00190	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LB4E_RS00190	COG0517	IMP dehydrogenase activity
LB4E_RS00205	COG0840	transmembrane signaling receptor activity
LB4E_RS00205	COG0840	transmembrane signaling receptor activity
LB4E_RS00215	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LB4E_RS00220	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
LB4E_RS00270	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LB4E_RS00275	COG1045	serine acetyltransferase
LB4E_RS00335	COG1024	Enoyl-CoA hydratase
LB4E_RS00445	COG3328	transposase activity
LB4E_RS00515	COG0705	Rhomboid family
LB4E_RS00615	COG1162	GTPase activity
LB4E_RS00650	COG2801	Transposase and inactivated derivatives
LB4E_RS00690	COG1132	(ABC) transporter
LB4E_RS00695	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
LB4E_RS00785	COG1847	R3H domain protein
LB4E_RS00795	COG0280	phosphate acetyltransferase
LB4E_RS00795	COG0281	malic enzyme
LB4E_RS00845	COG0564	pseudouridine synthase activity
LB4E_RS00850	COG0564	pseudouridine synthase activity
LB4E_RS00880	COG0483	inositol monophosphate 1-phosphatase activity
LB4E_RS00915	COG2949	membrane
LB4E_RS00940	COG4942	peptidase
LB4E_RS01000	COG0745	RESPONSE REGULATOR receiver
LB4E_RS01025	COG0494	nUDIX hydrolase
LB4E_RS01030	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
LB4E_RS01035	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LB4E_RS01090	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LB4E_RS01120	COG0538	isocitrate dehydrogenase activity
LB4E_RS01130	COG0745	RESPONSE REGULATOR receiver
LB4E_RS01140	COG3956	TIGRFAM MazG family protein
LB4E_RS01175	COG4221	oxidoreductase activity
LB4E_RS01185	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LB4E_RS01205	COG2271	Major facilitator Superfamily
LB4E_RS01215	COG1560	Kdo2-lipid A biosynthetic process
LB4E_RS01280	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LB4E_RS01285	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LB4E_RS01295	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LB4E_RS01330	COG2030	dehydratase
LB4E_RS01375	COG1309	transcriptional regulator
LB4E_RS01390	COG1960	acyl-CoA dehydrogenase activity
LB4E_RS01420	COG1032	radical SAM domain protein
LB4E_RS01530	COG0019	diaminopimelate decarboxylase activity
LB4E_RS01550	COG4942	peptidase
LB4E_RS01550	COG1388	LysM domain
LB4E_RS01575	COG1024	Enoyl-CoA hydratase
LB4E_RS01620	COG0514	ATP-dependent DNA helicase (RecQ)
LB4E_RS01635	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LB4E_RS01735	COG1366	Belongs to the anti-sigma-factor antagonist family
LB4E_RS01755	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LB4E_RS01770	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LB4E_RS01785	COG0640	Transcriptional regulator
LB4E_RS01825	COG1741	Belongs to the pirin family
LB4E_RS01835	COG1217	gtp-binding protein TYPA
LB4E_RS01915	COG1253	flavin adenine dinucleotide binding
LB4E_RS01980	COG5001	Diguanylate cyclase
LB4E_RS01990	COG0840	transmembrane signaling receptor activity
LB4E_RS02020	COG1024	Enoyl-CoA hydratase
LB4E_RS02045	COG1595	DNA-templated transcription, initiation
LB4E_RS02070	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LB4E_RS02120	COG4589	Belongs to the CDS family
LB4E_RS02130	COG0750	zinc metalloprotease
LB4E_RS02250	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LB4E_RS02250	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LB4E_RS02300	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LB4E_RS02345	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LB4E_RS02370	COG1136	(ABC) transporter
LB4E_RS02380	COG2385	sporulation resulting in formation of a cellular spore
LB4E_RS02445	COG1858	cytochrome C peroxidase
LB4E_RS02465	COG1216	Glycosyl transferase, family 2
LB4E_RS02465	COG0463	Glycosyl transferase, family 2
LB4E_RS02500	COG1988	membrane-bound metal-dependent
LB4E_RS02520	COG4456	Virulence-associated protein
LB4E_RS02535	COG0204	Acyl-transferase
LB4E_RS02540	COG0671	phosphoesterase, PA-phosphatase related
LB4E_RS02555	COG4565	transcriptional regulatory protein
LB4E_RS02585	COG3011	Protein conserved in bacteria
LB4E_RS02590	COG0739	heme binding
LB4E_RS02620	COG1396	sequence-specific DNA binding
LB4E_RS02650	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LB4E_RS02720	COG0850	regulation of cytokinetic process
LB4E_RS02755	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LB4E_RS02785	COG2181	nitrate reductase activity
LB4E_RS02785	COG0247	lactate metabolic process
LB4E_RS02805	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
LB4E_RS02835	COG1181	Belongs to the D-alanine--D-alanine ligase family
LB4E_RS02895	COG0598	Magnesium transport protein CorA
LB4E_RS02930	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LB4E_RS02930	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
LB4E_RS02955	COG0793	Belongs to the peptidase S41A family
LB4E_RS02965	COG1183	phosphatidylcholine synthase activity
LB4E_RS03030	COG1473	amidohydrolase
LB4E_RS03035	COG0475	glutathione-regulated potassium exporter activity
LB4E_RS03085	COG1295	ribonuclease BN
LB4E_RS03195	COG1157	protein secretion by the type III secretion system
LB4E_RS03200	COG1317	bacterial-type flagellum organization
LB4E_RS03210	COG1766	The M ring may be actively involved in energy transduction
LB4E_RS03255	COG1368	sulfuric ester hydrolase activity
LB4E_RS03300	COG0028	Belongs to the TPP enzyme family
LB4E_RS03305	COG0440	acetolactate synthase activity
LB4E_RS03320	COG1472	Belongs to the glycosyl hydrolase 3 family
LB4E_RS03325	COG2755	lipolytic protein G-D-S-L family
LB4E_RS03365	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LB4E_RS03420	COG0488	(ABC) transporter
LB4E_RS03455	COG3920	Histidine kinase
LB4E_RS03475	COG5001	Diguanylate cyclase
LB4E_RS03475	COG4251	negative regulation of phosphorylation
LB4E_RS03475	COG2203	Gaf domain
LB4E_RS03475	COG3706	GGDEF domain
LB4E_RS03480	COG2379	hydroxypyruvate reductase
LB4E_RS03490	COG0708	Exodeoxyribonuclease III
LB4E_RS03565	COG3458	cephalosporin-C deacetylase activity
LB4E_RS03620	COG3958	Transketolase
LB4E_RS03640	COG2030	dehydratase
LB4E_RS03660	COG0339	signal peptide processing
LB4E_RS03670	COG0625	glutathione transferase activity
LB4E_RS03675	COG1028	Short-chain dehydrogenase reductase Sdr
LB4E_RS03695	COG0688	phosphatidylethanolamine metabolic process
LB4E_RS03705	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LB4E_RS03705	COG1776	CheC inhibitor of MCP methylation
LB4E_RS03715	COG1338	Plays a role in the flagellum-specific transport system
LB4E_RS03720	COG1987	bacterial-type flagellum assembly
LB4E_RS03725	COG1684	flagellar biosynthetic protein fliR
LB4E_RS03740	COG1419	protein localization to endoplasmic reticulum
LB4E_RS03755	COG1191	sigma factor activity
LB4E_RS03780	COG0194	GDP metabolic process
LB4E_RS03790	COG1199	ATP-dependent helicase activity
LB4E_RS03795	COG0733	neurotransmitter:sodium symporter activity
LB4E_RS03835	COG2208	phosphoserine phosphatase activity
LB4E_RS03835	COG2770	Histidine kinase
LB4E_RS03865	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LB4E_RS03865	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LB4E_RS04025	COG4786	Flagellar basal body rod
LB4E_RS04030	COG0735	belongs to the Fur family
LB4E_RS04040	COG0753	catalase activity
LB4E_RS04085	COG0724	RNA recognition motif
LB4E_RS04105	COG0805	protein transport
LB4E_RS04120	COG3118	belongs to the thioredoxin family
LB4E_RS04130	COG1960	acyl-CoA dehydrogenase activity
LB4E_RS04370	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LB4E_RS04395	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LB4E_RS04405	COG0352	thiamine-phosphate diphosphorylase activity
LB4E_RS04435	COG1649	PFAM Uncharacterised BCR, COG1649
LB4E_RS04435	COG0726	polysaccharide deacetylase
LB4E_RS04485	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LB4E_RS04510	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LB4E_RS04515	COG0508	dehydrogenase complex catalyzes the overall conversion of
LB4E_RS04520	COG0022	dehydrogenase e1 component
LB4E_RS04520	COG0508	dehydrogenase complex catalyzes the overall conversion of
LB4E_RS04525	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LB4E_RS04530	COG0745	RESPONSE REGULATOR receiver
LB4E_RS04535	COG2205	protein histidine kinase activity
LB4E_RS04575	COG3876	Protein conserved in bacteria
LB4E_RS04615	COG1127	ABC transporter
LB4E_RS04620	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LB4E_RS04635	COG2813	Specifically methylates the guanine in position
LB4E_RS04635	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LB4E_RS04650	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LB4E_RS04665	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LB4E_RS04670	COG1776	CheC inhibitor of MCP methylation
LB4E_RS04670	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LB4E_RS04680	COG0330	HflC and HflK could
LB4E_RS04685	COG0330	HflC and HflK could
LB4E_RS04705	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LB4E_RS04720	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LB4E_RS04770	COG0463	Glycosyl transferase, family 2
LB4E_RS04785	COG0444	Belongs to the ABC transporter superfamily
LB4E_RS04805	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LB4E_RS04820	COG1595	DNA-templated transcription, initiation
LB4E_RS04835	COG0542	response to heat
LB4E_RS04840	COG0405	Gamma-glutamyltransferase
LB4E_RS04860	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LB4E_RS04865	COG0271	Belongs to the BolA IbaG family
LB4E_RS04870	COG0271	Belongs to the BolA IbaG family
LB4E_RS04875	COG0842	Transport permease protein
LB4E_RS04880	COG1131	(ABC) transporter
LB4E_RS04885	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LB4E_RS04900	COG1234	tRNA 3'-trailer cleavage
LB4E_RS04935	COG0616	signal peptide processing
LB4E_RS04970	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LB4E_RS04975	COG0083	homoserine kinase activity
LB4E_RS04990	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LB4E_RS04990	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LB4E_RS05000	COG0156	8-amino-7-oxononanoate synthase activity
LB4E_RS05010	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LB4E_RS05040	COG1496	oxidoreductase activity
LB4E_RS05090	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LB4E_RS05100	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LB4E_RS05190	COG0312	modulator of DNA gyrase
LB4E_RS05195	COG0312	modulator of DNA gyrase
LB4E_RS05240	COG1047	Peptidyl-prolyl cis-trans
LB4E_RS05255	COG0446	pyridine nucleotide-disulphide oxidoreductase
LB4E_RS05255	COG1902	pentaerythritol trinitrate reductase activity
LB4E_RS05280	COG1360	Flagellar Motor Protein
LB4E_RS05300	COG0784	Response regulator, receiver
LB4E_RS05300	COG4191	Histidine kinase
LB4E_RS05365	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LB4E_RS05395	COG4771	TonB-dependent receptor
LB4E_RS05485	COG2208	phosphoserine phosphatase activity
LB4E_RS05490	COG1366	Belongs to the anti-sigma-factor antagonist family
LB4E_RS05495	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LB4E_RS05520	COG0840	transmembrane signaling receptor activity
LB4E_RS05520	COG3290	protein histidine kinase activity
LB4E_RS05525	COG0643	Histidine kinase
LB4E_RS05525	COG2198	Histidine kinase
LB4E_RS05535	COG0745	RESPONSE REGULATOR receiver
LB4E_RS05540	COG2201	protein-glutamate methylesterase activity
LB4E_RS05575	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LB4E_RS05585	COG2096	Adenosyltransferase
LB4E_RS05605	COG2801	Transposase and inactivated derivatives
LB4E_RS05605	COG3415	Transposase
LB4E_RS05625	COG0616	signal peptide processing
LB4E_RS05685	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LB4E_RS05720	COG1104	cysteine desulfurase activity
LB4E_RS05740	COG0586	Pfam SNARE associated Golgi protein
LB4E_RS05770	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LB4E_RS05800	COG1696	Membrane protein involved in D-alanine export
LB4E_RS05805	COG1187	pseudouridine synthase activity
LB4E_RS05830	COG4335	DNA alkylation repair
LB4E_RS05875	COG1022	Amp-dependent synthetase and ligase
LB4E_RS05880	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LB4E_RS05895	COG1218	3'(2'),5'-bisphosphate nucleotidase
LB4E_RS05915	COG0848	biopolymer transport protein
LB4E_RS05920	COG0811	peptide transport
LB4E_RS05925	COG0497	DNA recombination
LB4E_RS05930	COG1639	'signal transduction protein
LB4E_RS05935	COG1028	Short-chain dehydrogenase reductase Sdr
LB4E_RS05940	COG0640	Transcriptional regulator
LB4E_RS05950	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
LB4E_RS05970	COG0012	GTP binding
LB4E_RS06000	COG0489	protein tyrosine kinase activity
LB4E_RS06010	COG0508	dehydrogenase complex catalyzes the overall conversion of
LB4E_RS06020	COG2133	pyrroloquinoline quinone binding
LB4E_RS06145	COG1459	type II secretion system
LB4E_RS06150	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LB4E_RS06165	COG0739	heme binding
LB4E_RS06195	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LB4E_RS06235	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LB4E_RS06280	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
LB4E_RS06310	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
LB4E_RS06310	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
LB4E_RS06315	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
LB4E_RS06315	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
LB4E_RS06325	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LB4E_RS06340	COG0024	Methionine aminopeptidase
LB4E_RS06445	COG0348	domain, Protein
LB4E_RS06510	COG0492	ferredoxin-NADP+ reductase activity
LB4E_RS06520	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LB4E_RS06565	COG2267	carboxylic ester hydrolase activity
LB4E_RS06585	COG1053	succinate dehydrogenase
LB4E_RS06665	COG0784	Response regulator, receiver
LB4E_RS06665	COG5002	protein histidine kinase activity
LB4E_RS06665	COG2205	protein histidine kinase activity
LB4E_RS06680	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
LB4E_RS06765	COG1639	'signal transduction protein
LB4E_RS06770	COG1119	ATPase activity
LB4E_RS06795	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LB4E_RS06805	COG4251	negative regulation of phosphorylation
LB4E_RS06810	COG2201	protein-glutamate methylesterase activity
LB4E_RS06815	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LB4E_RS06840	COG4191	Histidine kinase
LB4E_RS06840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LB4E_RS06845	COG4753	response regulator
LB4E_RS06845	COG2207	Transcriptional regulator
LB4E_RS06860	COG2361	Protein of unknown function DUF86
LB4E_RS06900	COG1381	Involved in DNA repair and RecF pathway recombination
LB4E_RS06910	COG1480	7TM receptor with intracellular HD hydrolase
LB4E_RS06915	COG1702	phosphate starvation-inducible protein PhoH
LB4E_RS06925	COG0305	Participates in initiation and elongation during chromosome replication
LB4E_RS06940	COG0629	single-stranded DNA binding
LB4E_RS06950	COG2843	Capsule synthesis protein
LB4E_RS06975	COG0471	metal ion transport
LB4E_RS06995	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LB4E_RS07000	COG1088	dTDP-glucose 4,6-dehydratase activity
LB4E_RS07010	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
LB4E_RS07045	COG1442	glycosyl transferase family 8
LB4E_RS07070	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LB4E_RS07075	COG1215	transferase activity, transferring glycosyl groups
LB4E_RS07085	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
LB4E_RS07095	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LB4E_RS07105	COG3958	Transketolase
LB4E_RS07110	COG3959	Transketolase, thiamine diphosphate binding domain
LB4E_RS07125	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
LB4E_RS07130	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
LB4E_RS07210	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LB4E_RS07240	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LB4E_RS07310	COG0758	DNA mediated transformation
LB4E_RS07335	COG1582	Flagellar protein (FlbD)
LB4E_RS07345	COG1360	Flagellar Motor Protein
LB4E_RS07360	COG1366	Belongs to the anti-sigma-factor antagonist family
LB4E_RS07365	COG2010	Cytochrome c
LB4E_RS07405	COG1484	DNA-dependent DNA replication
LB4E_RS07420	COG1605	Chorismate mutase
LB4E_RS07420	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
LB4E_RS07490	COG1215	transferase activity, transferring glycosyl groups
LB4E_RS07520	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LB4E_RS07530	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LB4E_RS07550	COG0004	ammonium transporteR
LB4E_RS07555	COG0347	Belongs to the P(II) protein family
LB4E_RS07575	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LB4E_RS07590	COG3942	CHAP domain
LB4E_RS07600	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LB4E_RS07620	COG2199	diguanylate cyclase activity
LB4E_RS07620	COG2203	Gaf domain
LB4E_RS07655	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LB4E_RS07715	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LB4E_RS07735	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LB4E_RS07740	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LB4E_RS07750	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
LB4E_RS07820	COG0768	penicillin binding
LB4E_RS07845	COG0673	inositol 2-dehydrogenase activity
LB4E_RS07850	COG1678	Uncharacterized ACR, COG1678
LB4E_RS07910	COG2226	methyltransferase
LB4E_RS07925	COG1028	Short-chain dehydrogenase reductase Sdr
LB4E_RS07955	COG0704	Plays a role in the regulation of phosphate uptake
LB4E_RS07970	COG0739	heme binding
LB4E_RS08000	COG0783	Belongs to the Dps family
LB4E_RS08010	COG1639	'signal transduction protein
LB4E_RS08060	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LB4E_RS08070	COG0772	Belongs to the SEDS family
LB4E_RS08145	COG0724	RNA recognition motif
LB4E_RS08155	COG5464	transposase or invertase
LB4E_RS08170	COG1846	Transcriptional regulator
LB4E_RS08185	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LB4E_RS08195	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LB4E_RS08220	COG0839	Belongs to the complex I subunit 6 family
LB4E_RS08300	COG0596	Alpha beta hydrolase
LB4E_RS08305	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LB4E_RS08375	COG0840	transmembrane signaling receptor activity
LB4E_RS08380	COG0840	transmembrane signaling receptor activity
LB4E_RS08395	COG0527	aspartate kinase activity
LB4E_RS08400	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LB4E_RS08415	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
LB4E_RS08445	COG0183	Belongs to the thiolase family
LB4E_RS08510	COG4771	TonB-dependent receptor
LB4E_RS08540	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LB4E_RS08575	COG0183	Belongs to the thiolase family
LB4E_RS08660	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LB4E_RS08665	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LB4E_RS08675	COG3852	Histidine kinase
LB4E_RS08680	COG4191	Histidine kinase
LB4E_RS08690	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LB4E_RS08715	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LB4E_RS08745	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LB4E_RS08750	COG3920	Histidine kinase
LB4E_RS08750	COG2202	Pas domain
LB4E_RS08775	COG1937	Protein conserved in bacteria
LB4E_RS08795	COG0288	reversible hydration of carbon dioxide
LB4E_RS08820	COG0586	Pfam SNARE associated Golgi protein
LB4E_RS08850	COG0210	DNA helicase
LB4E_RS08870	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
LB4E_RS09030	COG1881	PFAM PEBP family protein
LB4E_RS09050	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
LB4E_RS09060	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LB4E_RS09100	COG0612	Peptidase, M16
LB4E_RS09105	COG0612	Peptidase, M16
LB4E_RS09130	COG1858	cytochrome C peroxidase
LB4E_RS09145	COG0840	transmembrane signaling receptor activity
LB4E_RS09170	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LB4E_RS09175	COG0250	Participates in transcription elongation, termination and antitermination
LB4E_RS09245	COG0739	heme binding
LB4E_RS09275	COG1063	alcohol dehydrogenase
LB4E_RS09285	COG4943	cyclic-guanylate-specific phosphodiesterase activity
LB4E_RS09330	COG1639	'signal transduction protein
LB4E_RS09360	COG4772	TonB-dependent receptor
LB4E_RS09375	COG3153	acetyltransferase
LB4E_RS09375	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LB4E_RS09380	COG0277	FAD linked oxidase domain protein
LB4E_RS09385	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LB4E_RS09400	COG1215	transferase activity, transferring glycosyl groups
LB4E_RS09440	COG0285	dihydrofolate synthase activity
LB4E_RS09555	COG1331	Highly conserved protein containing a thioredoxin domain
LB4E_RS09615	COG0463	Glycosyl transferase, family 2
LB4E_RS09670	COG3447	MASE1 domain protein
LB4E_RS09670	COG5002	protein histidine kinase activity
LB4E_RS09670	COG5001	Diguanylate cyclase
LB4E_RS09720	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
LB4E_RS09730	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LB4E_RS09755	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LB4E_RS09815	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LB4E_RS09830	COG0628	permease
LB4E_RS09855	COG0697	spore germination
LB4E_RS09860	COG0385	Bile acid
LB4E_RS09900	COG0784	Response regulator, receiver
LB4E_RS09905	COG4251	negative regulation of phosphorylation
LB4E_RS09915	COG2843	Capsule synthesis protein
LB4E_RS09945	COG4771	TonB-dependent receptor
LB4E_RS09970	COG3177	Filamentation induced by cAMP protein fic
LB4E_RS10015	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LB4E_RS10155	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LB4E_RS10190	COG0123	including yeast histone deacetylase and acetoin utilization protein
LB4E_RS10230	COG2267	carboxylic ester hydrolase activity
LB4E_RS10275	COG4772	TonB-dependent receptor
LB4E_RS10300	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LB4E_RS10305	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LB4E_RS10320	COG0631	protein serine/threonine phosphatase activity
LB4E_RS10330	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LB4E_RS10345	COG4191	Histidine kinase
LB4E_RS10355	COG0537	adenosine 5'-monophosphoramidase activity
LB4E_RS10365	COG1136	(ABC) transporter
LB4E_RS10380	COG0318	PFAM AMP-dependent synthetase and ligase
LB4E_RS10475	COG1862	Preprotein translocase
LB4E_RS10505	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LB4E_RS10505	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LB4E_RS10515	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
LB4E_RS10520	COG4208	sulfate ABC transporter
LB4E_RS10570	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
LB4E_RS10590	COG0741	lytic transglycosylase activity
LB4E_RS10640	COG0095	Lipoate-protein ligase
LB4E_RS10665	COG1234	tRNA 3'-trailer cleavage
LB4E_RS10675	COG0508	dehydrogenase complex catalyzes the overall conversion of
LB4E_RS10680	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LB4E_RS10745	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
LB4E_RS10750	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LB4E_RS10760	COG2198	Histidine kinase
LB4E_RS10760	COG0643	Histidine kinase
LB4E_RS10770	COG2201	protein-glutamate methylesterase activity
LB4E_RS10790	COG0287	Prephenate dehydrogenase
LB4E_RS10805	COG2183	response to ionizing radiation
LB4E_RS10805	COG0539	negative regulation of cytoplasmic translation
LB4E_RS10840	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LB4E_RS10840	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LB4E_RS10885	COG0612	Peptidase, M16
LB4E_RS10905	COG2003	Belongs to the UPF0758 family
LB4E_RS10930	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LB4E_RS11040	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LB4E_RS11045	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LB4E_RS11080	COG1304	FMN binding
LB4E_RS11090	COG0564	pseudouridine synthase activity
LB4E_RS11095	COG1757	Na H antiporter
LB4E_RS11160	COG0784	Response regulator, receiver
LB4E_RS11165	COG0784	Response regulator, receiver
LB4E_RS11165	COG4191	Histidine kinase
LB4E_RS11170	COG2199	diguanylate cyclase activity
LB4E_RS11170	COG2202	Pas domain
LB4E_RS11170	COG2200	EAL domain
LB4E_RS11205	COG0463	Glycosyl transferase, family 2
LB4E_RS11240	COG0450	alkyl hydroperoxide reductase
LB4E_RS11245	COG0719	Fe-S assembly protein
LB4E_RS11270	COG0859	PFAM glycosyl transferase family 9
LB4E_RS11320	COG0436	Aminotransferase
LB4E_RS11390	COG0174	glutamine synthetase
LB4E_RS11405	COG1309	transcriptional regulator
LB4E_RS11440	COG0356	it plays a direct role in the translocation of protons across the membrane
LB4E_RS11445	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LB4E_RS11545	COG0768	penicillin binding
LB4E_RS11550	COG0772	Belongs to the SEDS family
LB4E_RS11590	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
LB4E_RS11625	COG1959	2 iron, 2 sulfur cluster binding
LB4E_RS11640	COG2070	2-Nitropropane dioxygenase
LB4E_RS11685	COG0439	Biotin carboxylase
LB4E_RS11720	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
LB4E_RS11725	COG0793	Belongs to the peptidase S41A family
LB4E_RS11770	COG0835	chemotaxis
LB4E_RS11795	COG5002	protein histidine kinase activity
LB4E_RS11800	COG1830	Aldolase
LB4E_RS11845	COG1999	signal sequence binding
LB4E_RS11890	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LB4E_RS11900	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
LB4E_RS11960	COG0833	amino acid
LB4E_RS11985	COG0366	Alpha amylase catalytic
LB4E_RS11995	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LB4E_RS12005	COG3876	Protein conserved in bacteria
LB4E_RS12095	COG0500	methyltransferase
LB4E_RS12180	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
LB4E_RS12230	COG3119	arylsulfatase activity
LB4E_RS12260	COG2197	response regulator
LB4E_RS12265	COG4585	Histidine kinase
LB4E_RS12290	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LB4E_RS12295	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LB4E_RS12325	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
LB4E_RS12350	COG0741	lytic transglycosylase activity
LB4E_RS12510	COG0822	iron-sulfur transferase activity
LB4E_RS12565	COG0811	peptide transport
LB4E_RS12660	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LB4E_RS12685	COG4133	protoheme IX ABC transporter activity
LB4E_RS12700	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LB4E_RS12730	COG0514	ATP-dependent DNA helicase (RecQ)
LB4E_RS12735	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
LB4E_RS12740	COG1074	ATP-dependent DNA helicase activity
LB4E_RS12750	COG1131	(ABC) transporter
LB4E_RS12760	COG1028	Short-chain dehydrogenase reductase Sdr
LB4E_RS12775	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LB4E_RS12780	COG1639	'signal transduction protein
LB4E_RS12790	COG1131	(ABC) transporter
LB4E_RS12830	COG1366	Belongs to the anti-sigma-factor antagonist family
LB4E_RS12860	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LB4E_RS12865	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LB4E_RS12965	COG0196	riboflavin kinase activity
LB4E_RS12985	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
LB4E_RS12990	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LB4E_RS13030	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LB4E_RS13040	COG0463	Glycosyl transferase, family 2
LB4E_RS13045	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LB4E_RS13070	COG1487	ribonuclease activity
LB4E_RS13165	COG1960	acyl-CoA dehydrogenase activity
LB4E_RS13175	COG2086	electron transfer activity
LB4E_RS13180	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
LB4E_RS13195	COG0180	Tryptophanyl-tRNA synthetase
LB4E_RS13215	COG0488	(ABC) transporter
LB4E_RS13230	COG0385	Bile acid
LB4E_RS13250	COG0822	iron-sulfur transferase activity
LB4E_RS13265	COG0719	Fe-S assembly protein
LB4E_RS13270	COG0396	ATPase activity
LB4E_RS13305	COG1857	crispr-associated protein
LB4E_RS13360	COG2076	Multidrug Resistance protein
LB4E_RS13390	COG0625	glutathione transferase activity
LB4E_RS13460	COG2192	nodulation
LB4E_RS13480	COG1024	Enoyl-CoA hydratase
LB4E_RS13545	COG2166	iron-sulfur cluster assembly
LB4E_RS13680	COG4943	cyclic-guanylate-specific phosphodiesterase activity
LB4E_RS13690	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
LB4E_RS13730	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
LB4E_RS13765	COG2326	polyphosphate kinase activity
LB4E_RS13795	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LB4E_RS13800	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LB4E_RS13805	COG1858	cytochrome C peroxidase
LB4E_RS13840	COG4181	ATPase activity
LB4E_RS13860	COG1639	'signal transduction protein
LB4E_RS13900	COG1309	transcriptional regulator
LB4E_RS13940	COG0438	transferase activity, transferring glycosyl groups
LB4E_RS13945	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LB4E_RS13945	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LB4E_RS13985	COG0346	lactoylglutathione lyase activity
LB4E_RS14020	COG0251	oxidation-reduction process
LB4E_RS14030	COG0513	Belongs to the DEAD box helicase family
LB4E_RS14080	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LB4E_RS14095	COG0193	aminoacyl-tRNA hydrolase activity
LB4E_RS14160	COG1966	Carbon starvation protein
LB4E_RS14165	COG0484	heat shock protein binding
LB4E_RS14180	COG0604	alcohol dehydrogenase
LB4E_RS14200	COG0386	Belongs to the glutathione peroxidase family
LB4E_RS14210	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
LB4E_RS14235	COG3959	Transketolase, thiamine diphosphate binding domain
LB4E_RS14245	COG0142	geranyltranstransferase activity
LB4E_RS14430	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LB4E_RS14455	COG0784	Response regulator, receiver
LB4E_RS14455	COG2205	protein histidine kinase activity
LB4E_RS14495	COG1132	(ABC) transporter
LB4E_RS14510	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LB4E_RS14590	COG1040	competence protein
LB4E_RS14710	COG1573	uracil-dna glycosylase
LB4E_RS14730	COG0720	synthase
LB4E_RS14770	COG4884	unkown
LB4E_RS14770	COG3831	ATPase activity
LB4E_RS14830	COG0745	RESPONSE REGULATOR receiver
LB4E_RS14835	COG5002	protein histidine kinase activity
LB4E_RS14875	COG2832	Protein of unknown function (DUF454)
LB4E_RS14905	COG1815	bacterial-type flagellum-dependent cell motility
LB4E_RS14935	COG0698	ribose 5-phosphate isomerase
LB4E_RS14970	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LB4E_RS15050	COG0739	heme binding
LB4E_RS15065	COG1192	Involved in chromosome partitioning
LB4E_RS15090	COG4956	integral membrane protein (PIN domain superfamily)
LB4E_RS15110	COG1845	cytochrome c oxidase, subunit III
LB4E_RS15120	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LB4E_RS15145	COG0473	3-isopropylmalate dehydrogenase activity
LB4E_RS15155	COG2197	response regulator
LB4E_RS15160	COG2205	protein histidine kinase activity
LB4E_RS15185	COG0436	Aminotransferase
LB4E_RS15195	COG1360	Flagellar Motor Protein
LB4E_RS15300	COG2304	oxidoreductase activity
LB4E_RS15340	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LB4E_RS15345	COG1648	precorrin-2 dehydrogenase activity
LB4E_RS15345	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LB4E_RS15350	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LB4E_RS15350	COG1648	precorrin-2 dehydrogenase activity
LB4E_RS15365	COG0175	sulfate reduction
LB4E_RS15405	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LB4E_RS15415	COG0460	homoserine dehydrogenase
LB4E_RS15440	COG1132	(ABC) transporter
LB4E_RS15445	COG0512	Glutamine amidotransferase of anthranilate synthase
LB4E_RS15455	COG1960	acyl-CoA dehydrogenase activity
LB4E_RS15465	COG0183	Belongs to the thiolase family
LB4E_RS15470	COG2801	Transposase and inactivated derivatives
LB4E_RS15495	COG1408	metallophosphoesterase
LB4E_RS15520	COG1595	DNA-templated transcription, initiation
LB4E_RS15540	COG2885	chlorophyll binding
LB4E_RS15545	COG0488	(ABC) transporter
LB4E_RS15600	COG1846	Transcriptional regulator
LB4E_RS15605	COG2259	Doxx family
LB4E_RS15625	COG2081	HI0933 family
LB4E_RS15745	COG1024	Enoyl-CoA hydratase
LB4E_RS15745	COG1250	3-hydroxyacyl-CoA dehydrogenase
LB4E_RS15765	COG4174	ABC transporter (Permease)
LB4E_RS15775	COG0444	Belongs to the ABC transporter superfamily
LB4E_RS15830	COG0840	transmembrane signaling receptor activity
LB4E_RS15845	COG3858	chitin binding
LB4E_RS15845	COG1388	LysM domain
LB4E_RS15870	COG0167	dihydroorotate dehydrogenase activity
LB4E_RS15950	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LB4E_RS15955	COG0649	NAD binding
LB4E_RS16020	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LB4E_RS16025	COG1846	Transcriptional regulator
LB4E_RS16030	COG0386	Belongs to the glutathione peroxidase family
LB4E_RS16035	COG0693	protein deglycase activity
LB4E_RS16135	COG2363	Small membrane protein
LB4E_RS16180	COG0590	tRNA wobble adenosine to inosine editing
LB4E_RS16210	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
LB4E_RS16225	COG0084	hydrolase, TatD family'
LB4E_RS16265	COG1192	Involved in chromosome partitioning
LB4E_RS16275	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LB4E_RS16295	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LB4E_RS16500	COG0557	exoribonuclease II activity
LB4E_RS17255	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LB4E_RS17355	COG1611	Belongs to the LOG family