locus-tag	class	description
LIC_RS00010	COG0592	DNA-directed DNA polymerase activity
LIC_RS00025	COG0187	DNA topoisomerase II activity
LIC_RS00065	COG2204	response regulator
LIC_RS00100	COG0009	L-threonylcarbamoyladenylate synthase
LIC_RS00150	COG0483	inositol monophosphate 1-phosphatase activity
LIC_RS00160	COG1874	Beta-galactosidase
LIC_RS00165	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LIC_RS00170	COG0802	atpase or kinase
LIC_RS00180	COG0557	exoribonuclease II activity
LIC_RS00220	COG0840	transmembrane signaling receptor activity
LIC_RS00220	COG0840	transmembrane signaling receptor activity
LIC_RS00230	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LIC_RS00235	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
LIC_RS00275	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LIC_RS00280	COG1045	serine acetyltransferase
LIC_RS00295	COG0534	Mate efflux family protein
LIC_RS00300	COG1301	dicarboxylic acid transport
LIC_RS00325	COG2205	protein histidine kinase activity
LIC_RS00340	COG1024	Enoyl-CoA hydratase
LIC_RS00365	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LIC_RS00375	COG2226	methyltransferase
LIC_RS00485	COG1022	Amp-dependent synthetase and ligase
LIC_RS00505	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LIC_RS00605	COG0352	thiamine-phosphate diphosphorylase activity
LIC_RS00605	COG0351	phosphomethylpyrimidine kinase
LIC_RS00620	COG3852	Histidine kinase
LIC_RS00625	COG1162	GTPase activity
LIC_RS00700	COG1132	(ABC) transporter
LIC_RS00705	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
LIC_RS00725	COG1034	ATP synthesis coupled electron transport
LIC_RS00740	COG1595	DNA-templated transcription, initiation
LIC_RS00760	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LIC_RS00765	COG3977	Valine--pyruvate aminotransferase
LIC_RS00810	COG1847	R3H domain protein
LIC_RS00820	COG0281	malic enzyme
LIC_RS00820	COG0280	phosphate acetyltransferase
LIC_RS01005	COG0564	pseudouridine synthase activity
LIC_RS01035	COG0483	inositol monophosphate 1-phosphatase activity
LIC_RS01090	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LIC_RS01100	COG1845	cytochrome c oxidase, subunit III
LIC_RS01120	COG4956	integral membrane protein (PIN domain superfamily)
LIC_RS01140	COG1192	Involved in chromosome partitioning
LIC_RS01160	COG0739	heme binding
LIC_RS01205	COG4591	ABC-type transport system involved in lipoprotein release permease component
LIC_RS01230	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LIC_RS01235	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LIC_RS01255	COG3361	conserved protein (COG2071)
LIC_RS01300	COG0604	alcohol dehydrogenase
LIC_RS01305	COG0517	IMP dehydrogenase activity
LIC_RS01305	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LIC_RS01305	COG0617	tRNA 3'-terminal CCA addition
LIC_RS01315	COG1966	Carbon starvation protein
LIC_RS01375	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LIC_RS01385	COG0402	S-adenosylhomocysteine deaminase activity
LIC_RS01390	COG3942	CHAP domain
LIC_RS01405	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LIC_RS01455	COG0142	geranyltranstransferase activity
LIC_RS01460	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
LIC_RS01485	COG0720	synthase
LIC_RS01520	COG0584	glycerophosphoryl diester phosphodiesterase
LIC_RS01555	COG1815	bacterial-type flagellum-dependent cell motility
LIC_RS01580	COG2832	Protein of unknown function (DUF454)
LIC_RS01645	COG0698	ribose 5-phosphate isomerase
LIC_RS01680	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LIC_RS01720	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LIC_RS01745	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LIC_RS01760	COG0542	response to heat
LIC_RS01785	COG1366	Belongs to the anti-sigma-factor antagonist family
LIC_RS01820	COG1131	(ABC) transporter
LIC_RS01830	COG1639	'signal transduction protein
LIC_RS01835	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LIC_RS01850	COG0180	Tryptophanyl-tRNA synthetase
LIC_RS01865	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
LIC_RS01870	COG2086	electron transfer activity
LIC_RS01880	COG1960	acyl-CoA dehydrogenase activity
LIC_RS01935	COG2326	polyphosphate kinase activity
LIC_RS02030	COG0488	(ABC) transporter
LIC_RS02040	COG1408	metallophosphoesterase
LIC_RS02070	COG0183	Belongs to the thiolase family
LIC_RS02190	COG0210	DNA helicase
LIC_RS02235	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LIC_RS02250	COG0193	aminoacyl-tRNA hydrolase activity
LIC_RS02295	COG0347	Belongs to the P(II) protein family
LIC_RS02300	COG0004	ammonium transporteR
LIC_RS02310	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LIC_RS02315	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LIC_RS02325	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LIC_RS02355	COG1215	transferase activity, transferring glycosyl groups
LIC_RS02395	COG0346	lactoylglutathione lyase activity
LIC_RS02415	COG4932	domain protein
LIC_RS02415	COG5492	domain, Protein
LIC_RS02420	COG4932	domain protein
LIC_RS02420	COG5492	domain, Protein
LIC_RS02470	COG0724	RNA recognition motif
LIC_RS02520	COG1639	'signal transduction protein
LIC_RS02545	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LIC_RS02635	COG4085	toxin activity
LIC_RS02635	COG1525	nuclease
LIC_RS02635	COG0737	Belongs to the 5'-nucleotidase family
LIC_RS02700	COG4181	ATPase activity
LIC_RS02715	COG1678	Uncharacterized ACR, COG1678
LIC_RS02720	COG0673	inositol 2-dehydrogenase activity
LIC_RS02750	COG0768	penicillin binding
LIC_RS02765	COG1663	tetraacyldisaccharide 4'-kinase activity
LIC_RS02770	COG1132	(ABC) transporter
LIC_RS02775	COG4166	transmembrane transport
LIC_RS02780	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
LIC_RS02795	COG2885	chlorophyll binding
LIC_RS02800	COG0488	(ABC) transporter
LIC_RS02830	COG1960	acyl-CoA dehydrogenase activity
LIC_RS02855	COG1573	uracil-dna glycosylase
LIC_RS02890	COG0596	Alpha beta hydrolase
LIC_RS02905	COG2205	protein histidine kinase activity
LIC_RS02905	COG0784	Response regulator, receiver
LIC_RS02935	COG1999	signal sequence binding
LIC_RS02970	COG0460	homoserine dehydrogenase
LIC_RS03010	COG1132	(ABC) transporter
LIC_RS03015	COG0512	Glutamine amidotransferase of anthranilate synthase
LIC_RS03015	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LIC_RS03025	COG1960	acyl-CoA dehydrogenase activity
LIC_RS03035	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LIC_RS03035	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LIC_RS03045	COG0121	glutamine amidotransferase
LIC_RS03050	COG0004	ammonium transporteR
LIC_RS03060	COG1324	tolerance protein
LIC_RS03115	COG2030	dehydratase
LIC_RS03125	COG3119	arylsulfatase activity
LIC_RS03140	COG0783	Belongs to the Dps family
LIC_RS03170	COG0456	acetyltransferase
LIC_RS03185	COG0758	DNA mediated transformation
LIC_RS03195	COG3384	dioxygenase
LIC_RS03210	COG1582	Flagellar protein (FlbD)
LIC_RS03220	COG1360	Flagellar Motor Protein
LIC_RS03235	COG1366	Belongs to the anti-sigma-factor antagonist family
LIC_RS03250	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LIC_RS03260	COG0396	ATPase activity
LIC_RS03265	COG0719	Fe-S assembly protein
LIC_RS03270	COG2146	nitrite reductase [NAD(P)H] activity
LIC_RS03275	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LIC_RS03280	COG0822	iron-sulfur transferase activity
LIC_RS03310	COG4943	cyclic-guanylate-specific phosphodiesterase activity
LIC_RS03335	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LIC_RS03355	COG2226	methyltransferase
LIC_RS03390	COG0477	Major facilitator Superfamily
LIC_RS03395	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LIC_RS03445	COG1715	Restriction endonuclease
LIC_RS03460	COG4608	Belongs to the ABC transporter superfamily
LIC_RS03485	COG1116	anion transmembrane transporter activity
LIC_RS03510	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LIC_RS03520	COG1858	cytochrome C peroxidase
LIC_RS03535	COG0840	transmembrane signaling receptor activity
LIC_RS03605	COG1028	Short-chain dehydrogenase reductase Sdr
LIC_RS03680	COG4772	TonB-dependent receptor
LIC_RS03695	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LIC_RS03695	COG3153	acetyltransferase
LIC_RS03700	COG0277	FAD linked oxidase domain protein
LIC_RS03705	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LIC_RS03720	COG0739	heme binding
LIC_RS03725	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LIC_RS03730	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
LIC_RS03755	COG0196	riboflavin kinase activity
LIC_RS03785	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LIC_RS03810	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LIC_RS03815	COG0513	Belongs to the DEAD box helicase family
LIC_RS03820	COG0860	N-Acetylmuramoyl-L-alanine amidase
LIC_RS03865	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LIC_RS03870	COG0250	Participates in transcription elongation, termination and antitermination
LIC_RS03945	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LIC_RS03980	COG0612	Peptidase, M16
LIC_RS03985	COG0612	Peptidase, M16
LIC_RS04130	COG1024	Enoyl-CoA hydratase
LIC_RS04200	COG1138	Cytochrome C-type biogenesis protein
LIC_RS04205	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
LIC_RS04225	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LIC_RS04315	COG1090	epimerase
LIC_RS04335	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LIC_RS04350	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LIC_RS04405	COG0575	Belongs to the CDS family
LIC_RS04415	COG0750	zinc metalloprotease
LIC_RS04415	COG0750	zinc metalloprotease
LIC_RS04460	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LIC_RS04520	COG0243	molybdopterin cofactor binding
LIC_RS04555	COG4772	TonB-dependent receptor
LIC_RS04600	COG0848	biopolymer transport protein
LIC_RS04610	COG0811	peptide transport
LIC_RS04710	COG3959	Transketolase, thiamine diphosphate binding domain
LIC_RS04720	COG0142	geranyltranstransferase activity
LIC_RS04840	COG1857	crispr-associated protein
LIC_RS04850	COG1203	CRISPR-associated helicase, Cas3
LIC_RS04900	COG0488	(ABC) transporter
LIC_RS04905	COG0656	L-ascorbic acid biosynthetic process
LIC_RS04915	COG1408	metallophosphoesterase
LIC_RS04960	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LIC_RS04990	COG2267	carboxylic ester hydrolase activity
LIC_RS05005	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LIC_RS05035	COG0183	Belongs to the thiolase family
LIC_RS05060	COG2801	Transposase and inactivated derivatives
LIC_RS05080	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LIC_RS05105	COG2815	serine threonine protein kinase
LIC_RS05105	COG0515	serine threonine protein kinase
LIC_RS05125	COG2205	protein histidine kinase activity
LIC_RS05130	COG0745	RESPONSE REGULATOR receiver
LIC_RS05175	COG1652	LysM domain
LIC_RS05180	COG1366	Belongs to the anti-sigma-factor antagonist family
LIC_RS05225	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LIC_RS05245	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LIC_RS05275	COG4932	domain protein
LIC_RS05275	COG5492	domain, Protein
LIC_RS05295	COG0463	Glycosyl transferase, family 2
LIC_RS05355	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LIC_RS05360	COG0436	Aminotransferase
LIC_RS05415	COG3831	ATPase activity
LIC_RS05415	COG4884	unkown
LIC_RS05460	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
LIC_RS05465	COG1704	LemA family
LIC_RS05510	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LIC_RS05510	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
LIC_RS05555	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LIC_RS05555	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LIC_RS05585	COG1136	(ABC) transporter
LIC_RS05590	COG2385	sporulation resulting in formation of a cellular spore
LIC_RS05620	COG1858	cytochrome C peroxidase
LIC_RS05645	COG1215	transferase activity, transferring glycosyl groups
LIC_RS05675	COG1988	membrane-bound metal-dependent
LIC_RS05690	COG0596	Alpha beta hydrolase
LIC_RS05700	COG1703	isobutyryl-CoA mutase activity
LIC_RS05700	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LIC_RS05700	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LIC_RS05705	COG0204	Acyl-transferase
LIC_RS05710	COG0671	phosphoesterase, PA-phosphatase related
LIC_RS05725	COG4565	transcriptional regulatory protein
LIC_RS05760	COG1501	Belongs to the glycosyl hydrolase 31 family
LIC_RS05765	COG3011	Protein conserved in bacteria
LIC_RS05795	COG0038	chloride channel
LIC_RS05800	COG3706	GGDEF domain
LIC_RS05825	COG3706	GGDEF domain
LIC_RS05840	COG0469	pyruvate kinase activity
LIC_RS05845	COG0123	including yeast histone deacetylase and acetoin utilization protein
LIC_RS05875	COG3345	alpha-galactosidase
LIC_RS05880	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
LIC_RS05885	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LIC_RS05900	COG1028	Short-chain dehydrogenase reductase Sdr
LIC_RS05920	COG0739	heme binding
LIC_RS05940	COG1396	sequence-specific DNA binding
LIC_RS05970	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LIC_RS06005	COG2226	methyltransferase
LIC_RS06035	COG0850	regulation of cytokinetic process
LIC_RS06065	COG1054	Belongs to the UPF0176 family
LIC_RS06085	COG0596	Alpha beta hydrolase
LIC_RS06105	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
LIC_RS06115	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
LIC_RS06175	COG4251	negative regulation of phosphorylation
LIC_RS06180	COG0784	Response regulator, receiver
LIC_RS06185	COG4191	Histidine kinase
LIC_RS06185	COG0784	Response regulator, receiver
LIC_RS06275	COG0450	alkyl hydroperoxide reductase
LIC_RS06280	COG0719	Fe-S assembly protein
LIC_RS06325	COG0598	Magnesium transport protein CorA
LIC_RS06335	COG1309	transcriptional regulator
LIC_RS06365	COG0356	it plays a direct role in the translocation of protons across the membrane
LIC_RS06370	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LIC_RS06490	COG0768	penicillin binding
LIC_RS06495	COG0772	Belongs to the SEDS family
LIC_RS06520	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
LIC_RS06570	COG0439	Biotin carboxylase
LIC_RS06575	COG0511	ligase activity, forming carbon-carbon bonds
LIC_RS06580	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LIC_RS06595	COG1959	2 iron, 2 sulfur cluster binding
LIC_RS06605	COG2070	2-Nitropropane dioxygenase
LIC_RS06655	COG2181	nitrate reductase activity
LIC_RS06655	COG0247	lactate metabolic process
LIC_RS06680	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
LIC_RS06710	COG1181	Belongs to the D-alanine--D-alanine ligase family
LIC_RS06730	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LIC_RS06735	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LIC_RS06735	COG0116	Belongs to the methyltransferase superfamily
LIC_RS06745	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LIC_RS06750	COG0859	PFAM glycosyl transferase family 9
LIC_RS06755	COG0006	proline dipeptidase activity
LIC_RS06775	COG1473	amidohydrolase
LIC_RS06805	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
LIC_RS06820	COG1295	ribonuclease BN
LIC_RS06820	COG1959	2 iron, 2 sulfur cluster binding
LIC_RS06825	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LIC_RS06895	COG4774	siderophore transport
LIC_RS06905	COG2801	Transposase and inactivated derivatives
LIC_RS06925	COG1960	acyl-CoA dehydrogenase activity
LIC_RS06955	COG3958	Transketolase
LIC_RS06965	COG1063	alcohol dehydrogenase
LIC_RS06975	COG2030	dehydratase
LIC_RS06985	COG0339	signal peptide processing
LIC_RS06995	COG0625	glutathione transferase activity
LIC_RS07000	COG1028	Short-chain dehydrogenase reductase Sdr
LIC_RS07015	COG0688	phosphatidylethanolamine metabolic process
LIC_RS07025	COG1776	CheC inhibitor of MCP methylation
LIC_RS07025	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LIC_RS07035	COG1338	Plays a role in the flagellum-specific transport system
LIC_RS07040	COG1987	bacterial-type flagellum assembly
LIC_RS07050	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LIC_RS07060	COG1419	protein localization to endoplasmic reticulum
LIC_RS07075	COG1191	sigma factor activity
LIC_RS07100	COG0194	GDP metabolic process
LIC_RS07130	COG1766	The M ring may be actively involved in energy transduction
LIC_RS07140	COG1317	bacterial-type flagellum organization
LIC_RS07170	COG2089	acid synthase
LIC_RS07205	COG0840	transmembrane signaling receptor activity
LIC_RS07215	COG0028	Belongs to the TPP enzyme family
LIC_RS07220	COG0440	acetolactate synthase activity
LIC_RS07235	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LIC_RS07240	COG1472	Belongs to the glycosyl hydrolase 3 family
LIC_RS07245	COG2755	lipolytic protein G-D-S-L family
LIC_RS07290	COG0724	RNA recognition motif
LIC_RS07310	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LIC_RS07350	COG0488	(ABC) transporter
LIC_RS07375	COG4251	negative regulation of phosphorylation
LIC_RS07380	COG4565	transcriptional regulatory protein
LIC_RS07400	COG3706	GGDEF domain
LIC_RS07400	COG2203	Gaf domain
LIC_RS07400	COG4251	negative regulation of phosphorylation
LIC_RS07400	COG5001	Diguanylate cyclase
LIC_RS07405	COG2379	hydroxypyruvate reductase
LIC_RS07440	COG0708	Exodeoxyribonuclease III
LIC_RS07530	COG0492	ferredoxin-NADP+ reductase activity
LIC_RS07660	COG4555	ABC transporter
LIC_RS07670	COG2226	methyltransferase
LIC_RS07685	COG0024	Methionine aminopeptidase
LIC_RS07700	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LIC_RS07765	COG2208	phosphoserine phosphatase activity
LIC_RS07770	COG1366	Belongs to the anti-sigma-factor antagonist family
LIC_RS07775	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LIC_RS07780	COG0439	Biotin carboxylase
LIC_RS07810	COG0840	transmembrane signaling receptor activity
LIC_RS07810	COG3290	protein histidine kinase activity
LIC_RS07815	COG0643	Histidine kinase
LIC_RS07815	COG2198	Histidine kinase
LIC_RS07825	COG0745	RESPONSE REGULATOR receiver
LIC_RS07830	COG2201	protein-glutamate methylesterase activity
LIC_RS07835	COG2205	protein histidine kinase activity
LIC_RS07865	COG2096	Adenosyltransferase
LIC_RS07870	COG3104	oligopeptide transport
LIC_RS07875	COG0791	NLP P60 protein
LIC_RS07885	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
LIC_RS07885	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
LIC_RS07890	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
LIC_RS07890	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
LIC_RS07920	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
LIC_RS07935	COG5000	phosphorelay sensor kinase activity
LIC_RS07940	COG2204	response regulator
LIC_RS07950	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LIC_RS07960	COG2815	serine threonine protein kinase
LIC_RS07960	COG0515	serine threonine protein kinase
LIC_RS07995	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LIC_RS08035	COG0739	heme binding
LIC_RS08050	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LIC_RS08055	COG1459	type II secretion system
LIC_RS08110	COG1309	transcriptional regulator
LIC_RS08120	COG1063	alcohol dehydrogenase
LIC_RS08170	COG1193	negative regulation of DNA recombination
LIC_RS08225	COG0489	protein tyrosine kinase activity
LIC_RS08235	COG0163	prenyltransferase activity
LIC_RS08240	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
LIC_RS08255	COG0012	GTP binding
LIC_RS08265	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
LIC_RS08270	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LIC_RS08275	COG0640	Transcriptional regulator
LIC_RS08280	COG1028	Short-chain dehydrogenase reductase Sdr
LIC_RS08285	COG1639	'signal transduction protein
LIC_RS08295	COG0497	DNA recombination
LIC_RS08300	COG0811	peptide transport
LIC_RS08305	COG0848	biopolymer transport protein
LIC_RS08310	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LIC_RS08325	COG1218	3'(2'),5'-bisphosphate nucleotidase
LIC_RS08340	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LIC_RS08345	COG1022	Amp-dependent synthetase and ligase
LIC_RS08355	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LIC_RS08390	COG4335	DNA alkylation repair
LIC_RS08400	COG2133	pyrroloquinoline quinone binding
LIC_RS08425	COG1187	pseudouridine synthase activity
LIC_RS08465	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LIC_RS08470	COG1516	flagellar protein fliS
LIC_RS08495	COG0586	Pfam SNARE associated Golgi protein
LIC_RS08540	COG0666	response to abiotic stimulus
LIC_RS08545	COG0277	FAD linked oxidase domain protein
LIC_RS08550	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LIC_RS08625	COG0840	transmembrane signaling receptor activity
LIC_RS08640	COG4771	TonB-dependent receptor
LIC_RS08655	COG0726	polysaccharide deacetylase
LIC_RS08665	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LIC_RS08680	COG0358	DNA primase activity
LIC_RS08735	COG2239	Acts as a magnesium transporter
LIC_RS08740	COG1360	Flagellar Motor Protein
LIC_RS08765	COG0616	signal peptide processing
LIC_RS08775	COG0009	L-threonylcarbamoyladenylate synthase
LIC_RS08820	COG1902	pentaerythritol trinitrate reductase activity
LIC_RS08820	COG0446	pyridine nucleotide-disulphide oxidoreductase
LIC_RS08855	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LIC_RS08865	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LIC_RS08870	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LIC_RS08885	COG0312	modulator of DNA gyrase
LIC_RS08915	COG1022	Amp-dependent synthetase and ligase
LIC_RS08950	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LIC_RS08970	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LIC_RS08980	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LIC_RS09015	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LIC_RS09055	COG0560	Phosphoserine phosphatase
LIC_RS09075	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LIC_RS09085	COG0156	8-amino-7-oxononanoate synthase activity
LIC_RS09095	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LIC_RS09095	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LIC_RS09110	COG0083	homoserine kinase activity
LIC_RS09120	COG2267	carboxylic ester hydrolase activity
LIC_RS09145	COG0616	signal peptide processing
LIC_RS09180	COG1234	tRNA 3'-trailer cleavage
LIC_RS09195	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LIC_RS09200	COG1131	(ABC) transporter
LIC_RS09205	COG0842	Transport permease protein
LIC_RS09215	COG0271	Belongs to the BolA IbaG family
LIC_RS09220	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LIC_RS09240	COG0405	Gamma-glutamyltransferase
LIC_RS09245	COG0542	response to heat
LIC_RS09260	COG1595	DNA-templated transcription, initiation
LIC_RS09275	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LIC_RS09280	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LIC_RS09300	COG0444	Belongs to the ABC transporter superfamily
LIC_RS09315	COG0463	Glycosyl transferase, family 2
LIC_RS09365	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LIC_RS09380	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LIC_RS09400	COG0330	HflC and HflK could
LIC_RS09405	COG0330	HflC and HflK could
LIC_RS09415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LIC_RS09450	COG2813	Specifically methylates the guanine in position
LIC_RS09450	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LIC_RS09465	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LIC_RS09470	COG1127	ABC transporter
LIC_RS09495	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LIC_RS09505	COG0772	Belongs to the SEDS family
LIC_RS09600	COG3876	Protein conserved in bacteria
LIC_RS09650	COG4452	Inner membrane protein CreD
LIC_RS09660	COG2205	protein histidine kinase activity
LIC_RS09665	COG0745	RESPONSE REGULATOR receiver
LIC_RS09670	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LIC_RS09675	COG0508	dehydrogenase complex catalyzes the overall conversion of
LIC_RS09675	COG0022	dehydrogenase e1 component
LIC_RS09680	COG0508	dehydrogenase complex catalyzes the overall conversion of
LIC_RS09685	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LIC_RS09715	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LIC_RS09735	COG0726	polysaccharide deacetylase
LIC_RS09735	COG1649	PFAM Uncharacterised BCR, COG1649
LIC_RS09760	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
LIC_RS09765	COG0352	thiamine-phosphate diphosphorylase activity
LIC_RS09780	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LIC_RS09805	COG2200	EAL domain
LIC_RS09810	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LIC_RS09845	COG1028	Short-chain dehydrogenase reductase Sdr
LIC_RS09870	COG0617	tRNA 3'-terminal CCA addition
LIC_RS09925	COG0519	Catalyzes the synthesis of GMP from XMP
LIC_RS09930	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LIC_RS10090	COG1960	acyl-CoA dehydrogenase activity
LIC_RS10100	COG3118	belongs to the thioredoxin family
LIC_RS10115	COG0805	protein transport
LIC_RS10135	COG0724	RNA recognition motif
LIC_RS10155	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LIC_RS10170	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LIC_RS10200	COG2267	carboxylic ester hydrolase activity
LIC_RS10220	COG1053	succinate dehydrogenase
LIC_RS10305	COG0733	neurotransmitter:sodium symporter activity
LIC_RS10315	COG1199	ATP-dependent helicase activity
LIC_RS10355	COG3458	cephalosporin-C deacetylase activity
LIC_RS10365	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LIC_RS10375	COG4191	Histidine kinase
LIC_RS10390	COG0735	belongs to the Fur family
LIC_RS10395	COG4786	Flagellar basal body rod
LIC_RS10415	COG2801	Transposase and inactivated derivatives
LIC_RS10515	COG2801	Transposase and inactivated derivatives
LIC_RS10520	COG2205	protein histidine kinase activity
LIC_RS10535	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
LIC_RS10570	COG0728	peptidoglycan biosynthetic process
LIC_RS10615	COG1639	'signal transduction protein
LIC_RS10620	COG1119	ATPase activity
LIC_RS10625	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LIC_RS10640	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LIC_RS10650	COG4251	negative regulation of phosphorylation
LIC_RS10655	COG0745	RESPONSE REGULATOR receiver
LIC_RS10670	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LIC_RS10705	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LIC_RS10705	COG4191	Histidine kinase
LIC_RS10745	COG1381	Involved in DNA repair and RecF pathway recombination
LIC_RS10755	COG1480	7TM receptor with intracellular HD hydrolase
LIC_RS10760	COG1702	phosphate starvation-inducible protein PhoH
LIC_RS10770	COG0305	Participates in initiation and elongation during chromosome replication
LIC_RS10785	COG0629	single-stranded DNA binding
LIC_RS10820	COG0471	metal ion transport
LIC_RS10840	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LIC_RS10845	COG1088	dTDP-glucose 4,6-dehydratase activity
LIC_RS10865	COG0463	Glycosyl transferase, family 2
LIC_RS10865	COG1216	Glycosyl transferase, family 2
LIC_RS10885	COG1442	glycosyl transferase family 8
LIC_RS10910	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LIC_RS10940	COG0438	transferase activity, transferring glycosyl groups
LIC_RS10980	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
LIC_RS10990	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LIC_RS11000	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LIC_RS11015	COG0673	inositol 2-dehydrogenase activity
LIC_RS11020	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
LIC_RS11035	COG0363	glucosamine-6-phosphate deaminase activity
LIC_RS11045	COG2192	nodulation
LIC_RS11060	COG1454	alcohol dehydrogenase
LIC_RS11065	COG1083	cytidylyl-transferase
LIC_RS11070	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LIC_RS11075	COG2089	acid synthase
LIC_RS11085	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LIC_RS11090	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LIC_RS11095	COG2089	acid synthase
LIC_RS11105	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LIC_RS11110	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LIC_RS11115	COG1083	cytidylyl-transferase
LIC_RS11125	COG0463	Glycosyl transferase, family 2
LIC_RS11140	COG1132	(ABC) transporter
LIC_RS11160	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LIC_RS11165	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LIC_RS11180	COG2813	Specifically methylates the guanine in position
LIC_RS11185	COG0494	nUDIX hydrolase
LIC_RS11200	COG3958	Transketolase
LIC_RS11205	COG3959	Transketolase, thiamine diphosphate binding domain
LIC_RS11225	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LIC_RS11230	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
LIC_RS11230	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
LIC_RS11235	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LIC_RS11245	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
LIC_RS11255	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LIC_RS11285	COG0071	Belongs to the small heat shock protein (HSP20) family
LIC_RS11300	COG3541	Predicted nucleotidyltransferase
LIC_RS11305	COG1999	signal sequence binding
LIC_RS11345	COG0475	glutathione-regulated potassium exporter activity
LIC_RS11370	COG1073	alpha beta
LIC_RS11405	COG1830	Aldolase
LIC_RS11420	COG5002	protein histidine kinase activity
LIC_RS11495	COG0793	Belongs to the peptidase S41A family
LIC_RS11500	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
LIC_RS11575	COG1757	Na H antiporter
LIC_RS11580	COG0564	pseudouridine synthase activity
LIC_RS11590	COG1304	FMN binding
LIC_RS11620	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LIC_RS11625	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LIC_RS11695	COG0366	Alpha amylase catalytic
LIC_RS11710	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LIC_RS11715	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LIC_RS11740	COG2003	Belongs to the UPF0758 family
LIC_RS11770	COG0793	Belongs to the peptidase S41A family
LIC_RS11815	COG0577	efflux transmembrane transporter activity
LIC_RS11815	COG1136	(ABC) transporter
LIC_RS11825	COG0537	adenosine 5'-monophosphoramidase activity
LIC_RS11845	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LIC_RS11855	COG0631	protein serine/threonine phosphatase activity
LIC_RS11860	COG1028	Short-chain dehydrogenase reductase Sdr
LIC_RS11875	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LIC_RS11880	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LIC_RS11935	COG0095	Lipoate-protein ligase
LIC_RS11975	COG2409	Drug exporters of the RND superfamily
LIC_RS11975	COG1033	growth of symbiont in host cell
LIC_RS11990	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LIC_RS12000	COG2339	peptidase activity
LIC_RS12030	COG2755	lipolytic protein G-D-S-L family
LIC_RS12030	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
LIC_RS12040	COG1217	gtp-binding protein TYPA
LIC_RS12060	COG1741	Belongs to the pirin family
LIC_RS12130	COG4771	TonB-dependent receptor
LIC_RS12150	COG2843	Capsule synthesis protein
LIC_RS12165	COG4251	negative regulation of phosphorylation
LIC_RS12170	COG0784	Response regulator, receiver
LIC_RS12190	COG0385	Bile acid
LIC_RS12195	COG0697	spore germination
LIC_RS12200	COG0628	permease
LIC_RS12215	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LIC_RS12220	COG0673	inositol 2-dehydrogenase activity
LIC_RS12225	COG0154	amidase activity
LIC_RS12300	COG0174	glutamine synthetase
LIC_RS12370	COG0714	Associated with various cellular activities
LIC_RS12375	COG0436	Aminotransferase
LIC_RS12410	COG1136	(ABC) transporter
LIC_RS12410	COG0577	efflux transmembrane transporter activity
LIC_RS12430	COG1368	sulfuric ester hydrolase activity
LIC_RS12510	COG0539	negative regulation of cytoplasmic translation
LIC_RS12525	COG0287	Prephenate dehydrogenase
LIC_RS12530	COG0077	Prephenate dehydratase
LIC_RS12530	COG1605	Chorismate mutase
LIC_RS12535	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LIC_RS12545	COG2201	protein-glutamate methylesterase activity
LIC_RS12555	COG2198	Histidine kinase
LIC_RS12555	COG0643	Histidine kinase
LIC_RS12570	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LIC_RS12575	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
LIC_RS12630	COG0326	Molecular chaperone. Has ATPase activity
LIC_RS12660	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LIC_RS12720	COG0861	Integral membrane protein TerC family
LIC_RS12740	COG1595	DNA-templated transcription, initiation
LIC_RS12770	COG1024	Enoyl-CoA hydratase
LIC_RS12800	COG0840	transmembrane signaling receptor activity
LIC_RS12810	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LIC_RS12825	COG5001	Diguanylate cyclase
LIC_RS12880	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
LIC_RS12885	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LIC_RS12910	COG0515	serine threonine protein kinase
LIC_RS12940	COG4208	sulfate ABC transporter
LIC_RS12950	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
LIC_RS12975	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LIC_RS12975	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LIC_RS12990	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LIC_RS12995	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LIC_RS13005	COG1862	Preprotein translocase
LIC_RS13060	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LIC_RS13085	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LIC_RS13175	COG0484	heat shock protein binding
LIC_RS13190	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LIC_RS13215	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LIC_RS13230	COG0640	Transcriptional regulator
LIC_RS13425	COG4942	peptidase
LIC_RS13425	COG1388	LysM domain
LIC_RS13460	COG1024	Enoyl-CoA hydratase
LIC_RS13500	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LIC_RS13550	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
LIC_RS13560	COG0386	Belongs to the glutathione peroxidase family
LIC_RS13595	COG2234	aminopeptidase activity
LIC_RS13620	COG1487	ribonuclease activity
LIC_RS13710	COG3831	ATPase activity
LIC_RS13710	COG4884	unkown
LIC_RS13715	COG4884	unkown
LIC_RS13715	COG3831	ATPase activity
LIC_RS13755	COG0842	Transport permease protein
LIC_RS13760	COG1131	(ABC) transporter
LIC_RS13765	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LIC_RS13770	COG1074	ATP-dependent DNA helicase activity
LIC_RS13775	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
LIC_RS13780	COG0514	ATP-dependent DNA helicase (RecQ)
LIC_RS13800	COG1331	Highly conserved protein containing a thioredoxin domain
LIC_RS13830	COG0705	Rhomboid family
LIC_RS13850	COG0612	Peptidase, M16
LIC_RS13880	COG0195	Participates in both transcription termination and antitermination
LIC_RS13895	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LIC_RS13895	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LIC_RS13930	COG2267	carboxylic ester hydrolase activity
LIC_RS13940	COG2814	Major facilitator Superfamily
LIC_RS13980	COG1024	Enoyl-CoA hydratase
LIC_RS13990	COG0123	including yeast histone deacetylase and acetoin utilization protein
LIC_RS14050	COG1846	Transcriptional regulator
LIC_RS14065	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LIC_RS14075	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LIC_RS14115	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LIC_RS14145	COG1595	DNA-templated transcription, initiation
LIC_RS14180	COG1639	'signal transduction protein
LIC_RS14190	COG0028	Belongs to the TPP enzyme family
LIC_RS14200	COG1366	Belongs to the anti-sigma-factor antagonist family
LIC_RS14345	COG0183	Belongs to the thiolase family
LIC_RS14375	COG0742	ribosomal rna small subunit methyltransferase
LIC_RS14400	COG2197	response regulator
LIC_RS14405	COG4585	Histidine kinase
LIC_RS14435	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LIC_RS14440	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LIC_RS14480	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
LIC_RS14515	COG0741	lytic transglycosylase activity
LIC_RS14535	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LIC_RS14555	COG2314	TM2 domain
LIC_RS14765	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LIC_RS14815	COG1368	sulfuric ester hydrolase activity
LIC_RS14825	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
LIC_RS14880	COG0741	lytic transglycosylase activity
LIC_RS14880	COG0739	heme binding
LIC_RS14880	COG1196	nuclear chromosome segregation
LIC_RS14905	COG3831	ATPase activity
LIC_RS14905	COG4884	unkown
LIC_RS14910	COG0714	Associated with various cellular activities
LIC_RS14915	COG2425	protein containing a von Willebrand factor type A (vWA) domain
LIC_RS14925	COG3552	Protein containing von Willebrand factor type A (VWA) domain
LIC_RS14940	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LIC_RS14945	COG0527	aspartate kinase activity
LIC_RS14985	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
LIC_RS15005	COG0840	transmembrane signaling receptor activity
LIC_RS15015	COG0731	radical SAM domain protein
LIC_RS15050	COG1858	cytochrome C peroxidase
LIC_RS15055	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LIC_RS15090	COG1482	cell wall glycoprotein biosynthetic process
LIC_RS15105	COG1366	Belongs to the anti-sigma-factor antagonist family
LIC_RS15135	COG0539	negative regulation of cytoplasmic translation
LIC_RS15145	COG1639	'signal transduction protein
LIC_RS15150	COG0463	Glycosyl transferase, family 2
LIC_RS15175	COG0285	dihydrofolate synthase activity
LIC_RS15230	COG0514	ATP-dependent DNA helicase (RecQ)
LIC_RS15275	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LIC_RS15305	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LIC_RS15310	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LIC_RS15320	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LIC_RS15340	COG2217	Heavy metal translocating P-type atpase
LIC_RS15350	COG1937	Protein conserved in bacteria
LIC_RS15395	COG0288	reversible hydration of carbon dioxide
LIC_RS15415	COG0586	Pfam SNARE associated Golgi protein
LIC_RS15440	COG4692	amylo-alpha-1,6-glucosidase activity
LIC_RS15455	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
LIC_RS15485	COG0666	response to abiotic stimulus
LIC_RS15510	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LIC_RS15545	COG3876	Protein conserved in bacteria
LIC_RS15625	COG0833	amino acid
LIC_RS15635	COG1846	Transcriptional regulator
LIC_RS15645	COG2259	Doxx family
LIC_RS15660	COG2081	HI0933 family
LIC_RS15695	COG1040	competence protein
LIC_RS15705	COG3239	Fatty acid desaturase
LIC_RS15770	COG0519	Catalyzes the synthesis of GMP from XMP
LIC_RS15810	COG1881	PFAM PEBP family protein
LIC_RS15820	COG1309	transcriptional regulator
LIC_RS15865	COG0784	Response regulator, receiver
LIC_RS15865	COG2205	protein histidine kinase activity
LIC_RS15895	COG4585	Histidine kinase
LIC_RS15900	COG2197	response regulator
LIC_RS15955	COG1090	epimerase
LIC_RS15975	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LIC_RS15990	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LIC_RS16000	COG4191	Histidine kinase
LIC_RS16005	COG5002	protein histidine kinase activity
LIC_RS16015	COG0596	Alpha beta hydrolase
LIC_RS16040	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LIC_RS16055	COG4943	cyclic-guanylate-specific phosphodiesterase activity
LIC_RS16065	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
LIC_RS16105	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
LIC_RS16120	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LIC_RS16135	COG1960	acyl-CoA dehydrogenase activity
LIC_RS16170	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LIC_RS16175	COG1253	flavin adenine dinucleotide binding
LIC_RS16210	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LIC_RS16225	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LIC_RS16230	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LIC_RS16270	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
LIC_RS16270	COG1605	Chorismate mutase
LIC_RS16280	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LIC_RS16280	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LIC_RS16285	COG1484	DNA-dependent DNA replication
LIC_RS16300	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
LIC_RS16305	COG0534	Mate efflux family protein
LIC_RS16330	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LIC_RS16340	COG0667	Aldo Keto reductase
LIC_RS16360	COG0494	nUDIX hydrolase
LIC_RS16370	COG0584	glycerophosphoryl diester phosphodiesterase
LIC_RS16395	COG3263	regulation of cellular component size
LIC_RS16405	COG0456	acetyltransferase
LIC_RS16420	COG0784	Response regulator, receiver
LIC_RS16420	COG2198	Histidine kinase
LIC_RS16420	COG2205	protein histidine kinase activity
LIC_RS16500	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LIC_RS16505	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LIC_RS16570	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LIC_RS16580	COG1560	Kdo2-lipid A biosynthetic process
LIC_RS16590	COG2271	Major facilitator Superfamily
LIC_RS16615	COG0513	Belongs to the DEAD box helicase family
LIC_RS16620	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LIC_RS16625	COG4221	oxidoreductase activity
LIC_RS16665	COG3956	TIGRFAM MazG family protein
LIC_RS16675	COG0745	RESPONSE REGULATOR receiver
LIC_RS16685	COG0538	isocitrate dehydrogenase activity
LIC_RS16720	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LIC_RS16780	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LIC_RS16785	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
LIC_RS16790	COG0494	nUDIX hydrolase
LIC_RS16820	COG0745	RESPONSE REGULATOR receiver
LIC_RS16825	COG5002	protein histidine kinase activity
LIC_RS16880	COG2030	dehydratase
LIC_RS16885	COG1960	acyl-CoA dehydrogenase activity
LIC_RS16895	COG4942	peptidase
LIC_RS16905	COG1595	DNA-templated transcription, initiation
LIC_RS16915	COG2949	membrane
LIC_RS16975	COG1024	Enoyl-CoA hydratase
LIC_RS16975	COG1250	3-hydroxyacyl-CoA dehydrogenase
LIC_RS16980	COG0183	Belongs to the thiolase family
LIC_RS17045	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LIC_RS17125	COG0473	3-isopropylmalate dehydrogenase activity
LIC_RS17135	COG2197	response regulator
LIC_RS17140	COG5001	Diguanylate cyclase
LIC_RS17140	COG3447	MASE1 domain protein
LIC_RS17140	COG5002	protein histidine kinase activity
LIC_RS17165	COG0436	Aminotransferase
LIC_RS17180	COG1360	Flagellar Motor Protein
LIC_RS17230	COG0187	DNA topoisomerase II activity
LIC_RS17255	COG1231	oxidoreductase activity
LIC_RS17285	COG2304	oxidoreductase activity
LIC_RS17325	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LIC_RS17330	COG1648	precorrin-2 dehydrogenase activity
LIC_RS17330	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LIC_RS17335	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LIC_RS17335	COG1648	precorrin-2 dehydrogenase activity
LIC_RS17350	COG0175	sulfate reduction
LIC_RS17370	COG2801	Transposase and inactivated derivatives
LIC_RS17380	COG2801	Transposase and inactivated derivatives
LIC_RS17405	COG4174	ABC transporter (Permease)
LIC_RS17410	COG4239	(ABC) transporter, permease
LIC_RS17415	COG0444	Belongs to the ABC transporter superfamily
LIC_RS17420	COG4608	Belongs to the ABC transporter superfamily
LIC_RS17440	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LIC_RS17465	COG3290	protein histidine kinase activity
LIC_RS17465	COG0840	transmembrane signaling receptor activity
LIC_RS17475	COG0492	ferredoxin-NADP+ reductase activity
LIC_RS17495	COG0840	transmembrane signaling receptor activity
LIC_RS17500	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LIC_RS17540	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LIC_RS17555	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LIC_RS17615	COG0649	NAD binding
LIC_RS17665	COG0167	dihydroorotate dehydrogenase activity
LIC_RS17690	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
LIC_RS17705	COG1846	Transcriptional regulator
LIC_RS17710	COG0386	Belongs to the glutathione peroxidase family
LIC_RS17760	COG0739	heme binding
LIC_RS17760	COG1196	nuclear chromosome segregation
LIC_RS17760	COG0741	lytic transglycosylase activity
LIC_RS17805	COG2363	Small membrane protein
LIC_RS17815	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
LIC_RS17840	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LIC_RS17860	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LIC_RS17880	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
LIC_RS17895	COG0084	hydrolase, TatD family'
LIC_RS17930	COG1475	DNA binding
LIC_RS17935	COG1192	Involved in chromosome partitioning
LIC_RS17945	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LIC_RS17970	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LIC_RS18195	COG0557	exoribonuclease II activity
LIC_RS18485	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LIC_RS19180	COG1966	Carbon starvation protein
LIC_RS19185	COG1966	Carbon starvation protein
LIC_RS19270	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LIC_RS19520	COG2801	Transposase and inactivated derivatives
LIC_RS19560	COG5492	domain, Protein
LIC_RS19560	COG4932	domain protein