locus-tag	class	description
ABH19_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ABH19_RS00010	COG0592	DNA-directed DNA polymerase activity
ABH19_RS00015	COG0187	DNA topoisomerase II activity
ABH19_RS00020	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ABH19_RS00030	COG0602	queuosine metabolic process
ABH19_RS00035	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ABH19_RS00040	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ABH19_RS00045	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ABH19_RS00050	COG0582	viral genome integration into host DNA
ABH19_RS00115	COG1857	crispr-associated protein
ABH19_RS00130	COG1518	maintenance of DNA repeat elements
ABH19_RS00150	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ABH19_RS00155	COG3657	addiction module killer protein
ABH19_RS00180	COG0604	alcohol dehydrogenase
ABH19_RS00185	COG1752	Esterase of the alpha-beta hydrolase superfamily
ABH19_RS00190	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ABH19_RS00195	COG0494	nUDIX hydrolase
ABH19_RS00200	COG1061	Type III restriction enzyme res subunit
ABH19_RS00250	COG2226	methyltransferase
ABH19_RS00260	COG2095	MarC family integral membrane protein
ABH19_RS00275	COG5000	phosphorelay sensor kinase activity
ABH19_RS00280	COG2204	response regulator
ABH19_RS00315	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ABH19_RS00335	COG0126	phosphoglycerate kinase activity
ABH19_RS00340	COG0149	triose-phosphate isomerase activity
ABH19_RS00350	COG0747	negative chemotaxis
ABH19_RS00360	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ABH19_RS00365	COG0546	phosphoglycolate phosphatase activity
ABH19_RS00390	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ABH19_RS00395	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ABH19_RS00400	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ABH19_RS00405	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ABH19_RS00410	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ABH19_RS00415	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ABH19_RS00420	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ABH19_RS00435	COG0745	RESPONSE REGULATOR receiver
ABH19_RS00440	COG3850	Histidine kinase
ABH19_RS00440	COG5002	protein histidine kinase activity
ABH19_RS00450	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ABH19_RS00475	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ABH19_RS00485	COG0346	lactoylglutathione lyase activity
ABH19_RS00490	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ABH19_RS00495	COG2022	thiamine diphosphate biosynthetic process
ABH19_RS00500	COG0352	thiamine-phosphate diphosphorylase activity
ABH19_RS00520	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ABH19_RS00525	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ABH19_RS00535	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ABH19_RS00550	COG4608	Belongs to the ABC transporter superfamily
ABH19_RS00555	COG0444	Belongs to the ABC transporter superfamily
ABH19_RS00585	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ABH19_RS00590	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ABH19_RS00595	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ABH19_RS00600	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ABH19_RS00605	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ABH19_RS00625	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ABH19_RS00630	COG1199	ATP-dependent helicase activity
ABH19_RS00635	COG0583	DNA-binding transcription factor activity
ABH19_RS00650	COG0670	Belongs to the BI1 family
ABH19_RS00675	COG0237	dephospho-CoA kinase activity
ABH19_RS00680	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ABH19_RS00685	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ABH19_RS00690	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ABH19_RS00710	COG2885	chlorophyll binding
ABH19_RS00730	COG0557	exoribonuclease II activity
ABH19_RS00750	COG1573	uracil-dna glycosylase
ABH19_RS00790	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ABH19_RS00825	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ABH19_RS00830	COG3956	TIGRFAM MazG family protein
ABH19_RS00870	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ABH19_RS00875	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ABH19_RS00880	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ABH19_RS00985	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ABH19_RS01010	COG2226	methyltransferase
ABH19_RS01040	COG0840	transmembrane signaling receptor activity
ABH19_RS01055	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ABH19_RS01060	COG0509	glycine decarboxylation via glycine cleavage system
ABH19_RS01065	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ABH19_RS01075	COG0095	Lipoate-protein ligase
ABH19_RS01110	COG3852	Histidine kinase
ABH19_RS01115	COG2204	response regulator
ABH19_RS01120	COG1815	bacterial-type flagellum-dependent cell motility
ABH19_RS01125	COG1558	bacterial-type flagellum-dependent cell motility
ABH19_RS01135	COG1766	The M ring may be actively involved in energy transduction
ABH19_RS01140	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ABH19_RS01150	COG1157	protein secretion by the type III secretion system
ABH19_RS01170	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
ABH19_RS01195	COG1338	Plays a role in the flagellum-specific transport system
ABH19_RS01220	COG0300	oxidoreductase activity
ABH19_RS01250	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ABH19_RS01260	COG0840	transmembrane signaling receptor activity
ABH19_RS01265	COG2201	protein-glutamate methylesterase activity
ABH19_RS01270	COG2198	Histidine kinase
ABH19_RS01270	COG0643	Histidine kinase
ABH19_RS01270	COG0784	Response regulator, receiver
ABH19_RS01280	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ABH19_RS01285	COG1191	sigma factor activity
ABH19_RS01295	COG1419	protein localization to endoplasmic reticulum
ABH19_RS01305	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ABH19_RS01315	COG1987	bacterial-type flagellum assembly
ABH19_RS01385	COG0758	DNA mediated transformation
ABH19_RS01390	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ABH19_RS01395	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
ABH19_RS01400	COG4974	Belongs to the 'phage' integrase family
ABH19_RS01405	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ABH19_RS01410	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ABH19_RS01415	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ABH19_RS01425	COG0756	dUTP diphosphatase activity
ABH19_RS01430	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ABH19_RS01435	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ABH19_RS01440	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ABH19_RS01490	COG0582	viral genome integration into host DNA
ABH19_RS01590	COG3012	SEC-C Motif Domain Protein
ABH19_RS01610	COG0811	peptide transport
ABH19_RS01765	COG0301	tRNA thio-modification
ABH19_RS01770	COG2329	Antibiotic biosynthesis monooxygenase
ABH19_RS01810	COG2255	four-way junction helicase activity
ABH19_RS01815	COG0632	four-way junction helicase activity
ABH19_RS01820	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ABH19_RS01825	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ABH19_RS01830	COG4566	intracellular signal transduction
ABH19_RS01835	COG3852	Histidine kinase
ABH19_RS01840	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ABH19_RS01890	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ABH19_RS01895	COG0601	transmembrane transport
ABH19_RS01920	COG0004	ammonium transporteR
ABH19_RS01925	COG0347	Belongs to the P(II) protein family
ABH19_RS01930	COG0004	ammonium transporteR
ABH19_RS01935	COG2217	Heavy metal translocating P-type atpase
ABH19_RS01940	COG2199	diguanylate cyclase activity
ABH19_RS01940	COG2200	EAL domain
ABH19_RS01960	COG3118	belongs to the thioredoxin family
ABH19_RS01965	COG0308	aminopeptidase N
ABH19_RS01975	COG1742	UPF0060 membrane protein
ABH19_RS01980	COG0556	nucleotide-excision repair
ABH19_RS02000	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ABH19_RS02005	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ABH19_RS02040	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ABH19_RS02050	COG1222	aaa ATPase
ABH19_RS02055	COG4122	O-methyltransferase activity
ABH19_RS02065	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
ABH19_RS02070	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
ABH19_RS02075	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
ABH19_RS02105	COG5285	phytanoyl-CoA dioxygenase
ABH19_RS02110	COG1917	Cupin 2, conserved barrel domain protein
ABH19_RS02125	COG0477	Major facilitator Superfamily
ABH19_RS02180	COG1592	Rubrerythrin
ABH19_RS02190	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ABH19_RS02200	COG0582	viral genome integration into host DNA
ABH19_RS02255	COG0629	single-stranded DNA binding
ABH19_RS02300	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
ABH19_RS02365	COG5001	Diguanylate cyclase
ABH19_RS02365	COG3300	MHYT domain
ABH19_RS02425	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ABH19_RS02585	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
ABH19_RS02635	COG0037	tRNA processing
ABH19_RS02640	COG2104	thiamine diphosphate biosynthetic process
ABH19_RS02650	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
ABH19_RS02665	COG0268	Binds directly to 16S ribosomal RNA
ABH19_RS02680	COG0495	leucyl-tRNA aminoacylation
ABH19_RS02700	COG0477	Major facilitator Superfamily
ABH19_RS02735	COG0612	Peptidase, M16
ABH19_RS02740	COG0612	Peptidase, M16
ABH19_RS02780	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ABH19_RS02790	COG1881	PFAM PEBP family protein
ABH19_RS02810	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ABH19_RS02820	COG0101	tRNA pseudouridine synthase activity
ABH19_RS02830	COG0489	protein tyrosine kinase activity
ABH19_RS02840	COG2975	iron-sulfur cluster assembly
ABH19_RS02850	COG0443	Heat shock 70 kDa protein
ABH19_RS02855	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ABH19_RS02860	COG0316	Belongs to the HesB IscA family
ABH19_RS02865	COG0822	iron-sulfur transferase activity
ABH19_RS02870	COG1104	cysteine desulfurase activity
ABH19_RS02875	COG1959	2 iron, 2 sulfur cluster binding
ABH19_RS02890	COG1253	flavin adenine dinucleotide binding
ABH19_RS02905	COG2046	Belongs to the sulfate adenylyltransferase family
ABH19_RS02925	COG1032	radical SAM domain protein
ABH19_RS02930	COG2814	Major facilitator Superfamily
ABH19_RS02980	COG1598	PFAM Uncharacterised protein family UPF0150
ABH19_RS02985	COG0582	viral genome integration into host DNA
ABH19_RS03055	COG1294	oxidase, subunit
ABH19_RS03065	COG0446	pyridine nucleotide-disulphide oxidoreductase
ABH19_RS03095	COG2197	response regulator
ABH19_RS03100	COG5002	protein histidine kinase activity
ABH19_RS03105	COG1113	amino acid transport
ABH19_RS03120	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
ABH19_RS03125	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
ABH19_RS03165	COG2205	protein histidine kinase activity
ABH19_RS03180	COG2084	Dehydrogenase
ABH19_RS03185	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ABH19_RS03210	COG1104	cysteine desulfurase activity
ABH19_RS03260	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ABH19_RS03295	COG0628	permease
ABH19_RS03300	COG0066	3-isopropylmalate dehydratase activity
ABH19_RS03305	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ABH19_RS03315	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ABH19_RS03340	COG0076	glutamate decarboxylase activity
ABH19_RS03420	COG0366	Alpha amylase catalytic
ABH19_RS03435	COG1064	alcohol dehydrogenase
ABH19_RS03455	COG1024	Enoyl-CoA hydratase
ABH19_RS03460	COG0784	Response regulator, receiver
ABH19_RS03460	COG2205	protein histidine kinase activity
ABH19_RS03460	COG2198	Histidine kinase
ABH19_RS03495	COG1132	(ABC) transporter
ABH19_RS03515	COG1215	transferase activity, transferring glycosyl groups
ABH19_RS03520	COG1215	transferase activity, transferring glycosyl groups
ABH19_RS03525	COG1216	Glycosyl transferase, family 2
ABH19_RS03525	COG0463	Glycosyl transferase, family 2
ABH19_RS03540	COG2204	response regulator
ABH19_RS03555	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ABH19_RS03565	COG5002	protein histidine kinase activity
ABH19_RS03575	COG1215	transferase activity, transferring glycosyl groups
ABH19_RS03595	COG0438	transferase activity, transferring glycosyl groups
ABH19_RS03600	COG0438	transferase activity, transferring glycosyl groups
ABH19_RS03605	COG0438	transferase activity, transferring glycosyl groups
ABH19_RS03610	COG1215	transferase activity, transferring glycosyl groups
ABH19_RS03655	COG0668	transmembrane transport
ABH19_RS03660	COG2199	diguanylate cyclase activity
ABH19_RS03690	COG1672	PFAM Archaeal ATPase
ABH19_RS03690	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
ABH19_RS03710	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ABH19_RS03785	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ABH19_RS03820	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ABH19_RS03830	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ABH19_RS03840	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ABH19_RS03850	COG0363	glucosamine-6-phosphate deaminase activity
ABH19_RS03855	COG0837	glucose binding
ABH19_RS03900	COG4279	zinc finger
ABH19_RS03905	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ABH19_RS03925	COG3300	MHYT domain
ABH19_RS03925	COG5001	Diguanylate cyclase
ABH19_RS03930	COG3012	SEC-C Motif Domain Protein
ABH19_RS03950	COG3012	SEC-C Motif Domain Protein
ABH19_RS03965	COG3344	reverse transcriptase
ABH19_RS03990	COG2084	Dehydrogenase
ABH19_RS03995	COG0596	Alpha beta hydrolase
ABH19_RS04015	COG2801	Transposase and inactivated derivatives
ABH19_RS04105	COG0438	transferase activity, transferring glycosyl groups
ABH19_RS04160	COG0438	transferase activity, transferring glycosyl groups
ABH19_RS04160	COG1216	Glycosyl transferase, family 2
ABH19_RS04165	COG1216	Glycosyl transferase, family 2
ABH19_RS04165	COG0438	transferase activity, transferring glycosyl groups
ABH19_RS04170	COG3335	DDE superfamily endonuclease
ABH19_RS04190	COG0579	oxidoreductase
ABH19_RS04195	COG2801	Transposase and inactivated derivatives
ABH19_RS04215	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
ABH19_RS04225	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ABH19_RS04275	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ABH19_RS04275	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ABH19_RS04285	COG0477	Major facilitator Superfamily
ABH19_RS04335	COG1484	DNA-dependent DNA replication
ABH19_RS04340	COG4584	PFAM Integrase catalytic
ABH19_RS04340	COG2390	Transcriptional regulator
ABH19_RS04345	COG2801	Transposase and inactivated derivatives
ABH19_RS04420	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ABH19_RS04420	COG2199	diguanylate cyclase activity
ABH19_RS04445	COG1487	ribonuclease activity
ABH19_RS04450	COG4691	Plasmid stability protein
ABH19_RS04515	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ABH19_RS04520	COG0649	NAD binding
ABH19_RS04525	COG0651	ATP synthesis coupled electron transport
ABH19_RS04540	COG0651	ATP synthesis coupled electron transport
ABH19_RS04575	COG2308	Evidence 4 Homologs of previously reported genes of
ABH19_RS04635	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ABH19_RS04645	COG0667	Aldo Keto reductase
ABH19_RS04680	COG3328	transposase activity
ABH19_RS04705	COG3547	Transposase (IS116 IS110 IS902 family)
ABH19_RS04755	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ABH19_RS04760	COG3321	synthase
ABH19_RS04760	COG1028	Short-chain dehydrogenase reductase Sdr
ABH19_RS04760	COG0604	alcohol dehydrogenase
ABH19_RS04765	COG0535	radical SAM domain protein
ABH19_RS04770	COG3547	Transposase (IS116 IS110 IS902 family)
ABH19_RS04790	COG3328	transposase activity
ABH19_RS04795	COG3547	Transposase (IS116 IS110 IS902 family)
ABH19_RS04855	COG0837	glucose binding
ABH19_RS04860	COG0363	glucosamine-6-phosphate deaminase activity
ABH19_RS04865	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ABH19_RS04870	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ABH19_RS04875	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ABH19_RS04890	COG0544	peptidyl-prolyl cis-trans isomerase activity
ABH19_RS04895	COG0740	serine-type endopeptidase activity
ABH19_RS04900	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ABH19_RS04925	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ABH19_RS04935	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ABH19_RS04940	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ABH19_RS04945	COG0193	aminoacyl-tRNA hydrolase activity
ABH19_RS04950	COG0012	GTP binding
ABH19_RS04955	COG0360	Binds together with S18 to 16S ribosomal RNA
ABH19_RS04960	COG0629	single-stranded DNA binding
ABH19_RS04965	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ABH19_RS04975	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ABH19_RS04990	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ABH19_RS05005	COG1252	NADH dehydrogenase
ABH19_RS05030	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ABH19_RS05050	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ABH19_RS05060	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ABH19_RS05065	COG0222	ribosome binding
ABH19_RS05070	COG0085	RNA polymerase activity
ABH19_RS05075	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ABH19_RS05080	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ABH19_RS05085	COG0049	tRNA binding
ABH19_RS05090	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ABH19_RS05095	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ABH19_RS05100	COG0051	transcription antitermination factor activity, RNA binding
ABH19_RS05110	COG0088	Forms part of the polypeptide exit tunnel
ABH19_RS05115	COG0089	rRNA binding
ABH19_RS05125	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ABH19_RS05135	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ABH19_RS05140	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ABH19_RS05145	COG0255	Belongs to the universal ribosomal protein uL29 family
ABH19_RS05155	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ABH19_RS05160	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ABH19_RS05165	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ABH19_RS05170	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ABH19_RS05180	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ABH19_RS05185	COG1841	ribosomal large subunit assembly
ABH19_RS05190	COG0200	Binds to the 23S rRNA
ABH19_RS05195	COG0201	protein transport
ABH19_RS05210	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ABH19_RS05225	COG0202	RNA polymerase activity
ABH19_RS05230	COG0203	ribosomal protein L17
ABH19_RS05245	COG1091	dTDP-4-dehydrorhamnose reductase activity
ABH19_RS05255	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
ABH19_RS05260	COG0438	transferase activity, transferring glycosyl groups
ABH19_RS05275	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ABH19_RS05285	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ABH19_RS05290	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ABH19_RS05325	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ABH19_RS05335	COG0583	DNA-binding transcription factor activity
ABH19_RS05355	COG0842	Transport permease protein
ABH19_RS05355	COG1129	ABC transporter
ABH19_RS05410	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ABH19_RS05445	COG0784	Response regulator, receiver
ABH19_RS05455	COG0352	thiamine-phosphate diphosphorylase activity
ABH19_RS05460	COG0439	Biotin carboxylase
ABH19_RS05465	COG0511	ligase activity, forming carbon-carbon bonds
ABH19_RS05470	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ABH19_RS05475	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ABH19_RS05485	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ABH19_RS05490	COG1758	RNA polymerase activity
ABH19_RS05495	COG0194	GDP metabolic process
ABH19_RS05500	COG2052	Domain of unknown function (DUF370)
ABH19_RS05505	COG1561	YicC-like family, N-terminal region
ABH19_RS05525	COG0156	8-amino-7-oxononanoate synthase activity
ABH19_RS05530	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
ABH19_RS05535	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ABH19_RS05555	COG0752	glycyl-tRNA synthetase alpha subunit
ABH19_RS05560	COG0751	glycine-tRNA ligase activity
ABH19_RS05565	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ABH19_RS05565	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ABH19_RS05570	COG0307	riboflavin synthase, alpha
ABH19_RS05575	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
ABH19_RS05615	COG1950	PFAM Membrane protein of
ABH19_RS05620	COG1322	Protein conserved in bacteria
ABH19_RS05625	COG0129	dihydroxy-acid dehydratase activity
ABH19_RS05640	COG1492	cobalamin metabolic process
ABH19_RS05645	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
ABH19_RS05650	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ABH19_RS05655	COG3547	Transposase (IS116 IS110 IS902 family)
ABH19_RS05675	COG0114	fumarate hydratase activity
ABH19_RS05685	COG1254	Belongs to the acylphosphatase family
ABH19_RS05700	COG0067	glutamate synthase
ABH19_RS05700	COG0069	glutamate synthase activity
ABH19_RS05700	COG0070	glutamate synthase
ABH19_RS05705	COG3481	metal-dependent phosphohydrolase, HD sub domain
ABH19_RS05710	COG0277	FAD linked oxidase domain protein
ABH19_RS05745	COG0646	methionine synthase
ABH19_RS05745	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ABH19_RS05750	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ABH19_RS05755	COG0302	gtp cyclohydrolase
ABH19_RS05770	COG0204	Acyl-transferase
ABH19_RS05775	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ABH19_RS05780	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ABH19_RS05785	COG0287	Prephenate dehydrogenase
ABH19_RS05790	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
ABH19_RS05795	COG1605	Chorismate mutase
ABH19_RS05795	COG0077	Prephenate dehydratase
ABH19_RS05800	COG0217	transcriptional regulatory protein
ABH19_RS05830	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ABH19_RS05840	COG1489	DNA binding
ABH19_RS05845	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ABH19_RS05855	COG0105	UTP biosynthetic process
ABH19_RS05865	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ABH19_RS05930	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ABH19_RS05940	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ABH19_RS05970	COG0577	efflux transmembrane transporter activity
ABH19_RS05980	COG2084	Dehydrogenase
ABH19_RS06035	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ABH19_RS06040	COG4974	Belongs to the 'phage' integrase family
ABH19_RS06065	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ABH19_RS06085	COG0297	glycogen (starch) synthase activity
ABH19_RS06090	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ABH19_RS06090	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ABH19_RS06100	COG1388	LysM domain
ABH19_RS06100	COG3942	CHAP domain
ABH19_RS06125	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ABH19_RS06130	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ABH19_RS06185	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ABH19_RS06190	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ABH19_RS06205	COG1278	Cold shock
ABH19_RS06225	COG0305	Participates in initiation and elongation during chromosome replication
ABH19_RS06230	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
ABH19_RS06235	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ABH19_RS06240	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ABH19_RS06245	COG4166	transmembrane transport
ABH19_RS06275	COG0840	transmembrane signaling receptor activity
ABH19_RS06295	COG0825	malonyl-CoA metabolic process
ABH19_RS06300	COG0180	Tryptophanyl-tRNA synthetase
ABH19_RS06305	COG1994	Peptidase M50
ABH19_RS06315	COG3189	MarR family transcriptional regulator
ABH19_RS06320	COG0860	N-Acetylmuramoyl-L-alanine amidase
ABH19_RS06385	COG1715	Restriction endonuclease
ABH19_RS06425	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
ABH19_RS06435	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
ABH19_RS06480	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
ABH19_RS06505	COG3012	SEC-C Motif Domain Protein
ABH19_RS06585	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ABH19_RS06720	COG2885	chlorophyll binding
ABH19_RS06740	COG0488	(ABC) transporter
ABH19_RS06755	COG0477	Major facilitator Superfamily
ABH19_RS06800	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ABH19_RS06805	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ABH19_RS06815	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
ABH19_RS06835	COG1131	(ABC) transporter
ABH19_RS06840	COG0842	Transport permease protein
ABH19_RS06845	COG0842	Transport permease protein
ABH19_RS06865	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ABH19_RS06880	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ABH19_RS06885	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ABH19_RS06890	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ABH19_RS06905	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ABH19_RS06910	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ABH19_RS06910	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ABH19_RS06915	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ABH19_RS06915	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ABH19_RS06920	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ABH19_RS06925	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ABH19_RS06935	COG0215	cysteine-tRNA ligase activity
ABH19_RS06945	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ABH19_RS06955	COG0776	regulation of translation
ABH19_RS06960	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ABH19_RS06965	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ABH19_RS06970	COG0527	aspartate kinase activity
ABH19_RS06980	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ABH19_RS06995	COG0436	Aminotransferase
ABH19_RS07020	COG2226	methyltransferase
ABH19_RS07030	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ABH19_RS07045	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ABH19_RS07055	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
ABH19_RS07060	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ABH19_RS07070	COG1136	(ABC) transporter
ABH19_RS07085	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ABH19_RS07090	COG0742	ribosomal rna small subunit methyltransferase
ABH19_RS07105	COG0151	Belongs to the GarS family
ABH19_RS07110	COG0138	bifunctional purine biosynthesis protein purh
ABH19_RS07115	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ABH19_RS07120	COG0463	Glycosyl transferase, family 2
ABH19_RS07135	COG0671	phosphoesterase, PA-phosphatase related
ABH19_RS07140	COG1045	serine acetyltransferase
ABH19_RS07145	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ABH19_RS07145	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ABH19_RS07150	COG4956	integral membrane protein (PIN domain superfamily)
ABH19_RS07165	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ABH19_RS07185	COG1597	lipid kinase activity
ABH19_RS07195	COG0438	transferase activity, transferring glycosyl groups
ABH19_RS07200	COG0726	polysaccharide deacetylase
ABH19_RS07215	COG2835	tetraacyldisaccharide 4'-kinase activity
ABH19_RS07220	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ABH19_RS07250	COG0859	PFAM glycosyl transferase family 9
ABH19_RS07285	COG1663	tetraacyldisaccharide 4'-kinase activity
ABH19_RS07290	COG1519	Transferase
ABH19_RS07295	COG1132	(ABC) transporter
ABH19_RS07320	COG1215	transferase activity, transferring glycosyl groups
ABH19_RS07330	COG0463	Glycosyl transferase, family 2
ABH19_RS07340	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ABH19_RS07345	COG0673	inositol 2-dehydrogenase activity
ABH19_RS07360	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ABH19_RS07365	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ABH19_RS07375	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ABH19_RS07400	COG0473	3-isopropylmalate dehydrogenase activity
ABH19_RS07415	COG1797	cobyrinic acid a,c-diamide synthase activity
ABH19_RS07420	COG0406	alpha-ribazole phosphatase activity
ABH19_RS07425	COG0667	Aldo Keto reductase
ABH19_RS07455	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
ABH19_RS07460	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
ABH19_RS07485	COG0484	heat shock protein binding
ABH19_RS07490	COG0443	Heat shock 70 kDa protein
ABH19_RS07500	COG1420	regulation of RNA biosynthetic process
ABH19_RS07510	COG1566	PFAM secretion protein HlyD family protein
ABH19_RS07515	COG1538	Outer membrane efflux protein
ABH19_RS07520	COG2814	Major facilitator Superfamily
ABH19_RS07560	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ABH19_RS07565	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ABH19_RS07575	COG0343	queuine tRNA-ribosyltransferase activity
ABH19_RS07595	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ABH19_RS07600	COG0542	response to heat
ABH19_RS07650	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ABH19_RS07670	COG1192	Involved in chromosome partitioning
ABH19_RS07680	COG2135	peptidase activity
ABH19_RS07685	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
ABH19_RS07800	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
ABH19_RS07815	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ABH19_RS07860	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ABH19_RS07885	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ABH19_RS07890	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ABH19_RS07895	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ABH19_RS07905	COG1660	Displays ATPase and GTPase activities
ABH19_RS07945	COG1566	PFAM secretion protein HlyD family protein
ABH19_RS07985	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ABH19_RS07995	COG0157	Belongs to the NadC ModD family
ABH19_RS08000	COG0525	valine-tRNA ligase activity
ABH19_RS08005	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ABH19_RS08010	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ABH19_RS08020	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ABH19_RS08025	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ABH19_RS08050	COG3706	GGDEF domain
ABH19_RS08055	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
ABH19_RS08060	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ABH19_RS08065	COG1982	Orn Lys Arg decarboxylase major
ABH19_RS08070	COG1615	UPF0182 protein
ABH19_RS08075	COG0497	DNA recombination
ABH19_RS08085	COG0459	protein refolding
ABH19_RS08090	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ABH19_RS08095	COG0793	Belongs to the peptidase S41A family
ABH19_RS08110	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ABH19_RS08115	COG0335	large ribosomal subunit rRNA binding
ABH19_RS08120	COG0336	Belongs to the RNA methyltransferase TrmD family
ABH19_RS08130	COG1837	Belongs to the UPF0109 family
ABH19_RS08135	COG0228	four-way junction DNA binding
ABH19_RS08140	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ABH19_RS08145	COG0776	regulation of translation
ABH19_RS08150	COG0616	signal peptide processing
ABH19_RS08155	COG2183	response to ionizing radiation
ABH19_RS08155	COG0539	negative regulation of cytoplasmic translation
ABH19_RS08200	COG3620	sequence-specific DNA binding
ABH19_RS08200	COG0617	tRNA 3'-terminal CCA addition
ABH19_RS08200	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ABH19_RS08220	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ABH19_RS08255	COG0723	plastoquinol--plastocyanin reductase activity
ABH19_RS08275	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ABH19_RS08285	COG1573	uracil-dna glycosylase
ABH19_RS08290	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ABH19_RS08290	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ABH19_RS08295	COG0736	holo-[acyl-carrier-protein] synthase activity
ABH19_RS08300	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ABH19_RS08305	COG0612	Peptidase, M16
ABH19_RS08310	COG1185	polyribonucleotide nucleotidyltransferase activity
ABH19_RS08315	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ABH19_RS08320	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ABH19_RS08325	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ABH19_RS08335	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ABH19_RS08340	COG0195	Participates in both transcription termination and antitermination
ABH19_RS08345	COG0779	Required for maturation of 30S ribosomal subunits
ABH19_RS08360	COG0784	Response regulator, receiver
ABH19_RS08360	COG0835	chemotaxis
ABH19_RS08375	COG2326	polyphosphate kinase activity
ABH19_RS08385	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ABH19_RS08400	COG1480	7TM receptor with intracellular HD hydrolase
ABH19_RS08405	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ABH19_RS08410	COG0552	protein localization to endoplasmic reticulum
ABH19_RS08415	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ABH19_RS08425	COG0322	excinuclease ABC activity
ABH19_RS08430	COG0542	response to heat
ABH19_RS08445	COG0646	methionine synthase
ABH19_RS08445	COG1410	methionine synthase
ABH19_RS08450	COG1234	tRNA 3'-trailer cleavage
ABH19_RS08460	COG1217	gtp-binding protein TYPA
ABH19_RS08465	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ABH19_RS08485	COG1381	Involved in DNA repair and RecF pathway recombination
ABH19_RS08490	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ABH19_RS08495	COG0300	oxidoreductase activity
ABH19_RS08520	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
ABH19_RS08520	COG0662	Cupin 2, conserved barrel domain protein
ABH19_RS08530	COG1017	nitric oxide dioxygenase activity
ABH19_RS08530	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ABH19_RS08550	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ABH19_RS08550	COG0543	2 iron, 2 sulfur cluster binding
ABH19_RS08560	COG1959	2 iron, 2 sulfur cluster binding
ABH19_RS08580	COG1022	Amp-dependent synthetase and ligase
ABH19_RS08585	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
ABH19_RS08625	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ABH19_RS08630	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ABH19_RS08665	COG0166	Belongs to the GPI family
ABH19_RS08670	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ABH19_RS08690	COG3258	Cytochrome c
ABH19_RS08710	COG1215	transferase activity, transferring glycosyl groups
ABH19_RS08715	COG0457	Tetratricopeptide repeat
ABH19_RS08730	COG0492	ferredoxin-NADP+ reductase activity
ABH19_RS08755	COG3258	Cytochrome c
ABH19_RS08800	COG1459	type II secretion system
ABH19_RS08805	COG2165	general secretion pathway protein
ABH19_RS08825	COG3156	type II secretion system protein K
ABH19_RS08870	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
ABH19_RS08885	COG0347	Belongs to the P(II) protein family
ABH19_RS08890	COG0004	ammonium transporteR
ABH19_RS08900	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ABH19_RS08920	COG0713	ATP synthesis coupled electron transport
ABH19_RS08935	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ABH19_RS08960	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ABH19_RS08965	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ABH19_RS08970	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ABH19_RS08975	COG0653	protein targeting
ABH19_RS08980	COG0739	heme binding
ABH19_RS08985	COG1324	tolerance protein
ABH19_RS08990	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ABH19_RS09000	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ABH19_RS09010	COG1722	exodeoxyribonuclease VII activity
ABH19_RS09015	COG1570	exodeoxyribonuclease VII activity
ABH19_RS09025	COG1418	mRNA catabolic process
ABH19_RS09030	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
ABH19_RS09030	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ABH19_RS09060	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ABH19_RS09065	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ABH19_RS09070	COG1674	ftsk spoiiie
ABH19_RS09085	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ABH19_RS09090	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ABH19_RS09120	COG1127	ABC transporter
ABH19_RS09125	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ABH19_RS09130	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
ABH19_RS09140	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ABH19_RS09145	COG5002	protein histidine kinase activity
ABH19_RS09150	COG0745	RESPONSE REGULATOR receiver
ABH19_RS09160	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ABH19_RS09170	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
ABH19_RS09180	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ABH19_RS09185	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ABH19_RS09195	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ABH19_RS09200	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ABH19_RS09215	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ABH19_RS09220	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ABH19_RS09250	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ABH19_RS09255	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ABH19_RS09275	COG1657	PFAM Prenyltransferase squalene oxidase
ABH19_RS09295	COG1872	DUF167
ABH19_RS09305	COG0762	integral membrane protein
ABH19_RS09310	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ABH19_RS09320	COG1496	oxidoreductase activity
ABH19_RS09325	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ABH19_RS09340	COG1181	Belongs to the D-alanine--D-alanine ligase family
ABH19_RS09345	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ABH19_RS09350	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ABH19_RS09355	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ABH19_RS09360	COG0772	Belongs to the SEDS family
ABH19_RS09365	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ABH19_RS09370	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ABH19_RS09375	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ABH19_RS09380	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ABH19_RS09385	COG0768	penicillin binding
ABH19_RS09395	COG0275	rRNA processing
ABH19_RS09400	COG2001	Belongs to the MraZ family
ABH19_RS09410	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ABH19_RS09415	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ABH19_RS09420	COG0045	succinate-CoA ligase (ADP-forming) activity
ABH19_RS09440	COG0372	Belongs to the citrate synthase family
ABH19_RS09445	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ABH19_RS09450	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ABH19_RS09455	COG0045	succinate-CoA ligase (ADP-forming) activity
ABH19_RS09500	COG0438	transferase activity, transferring glycosyl groups
ABH19_RS09505	COG0438	transferase activity, transferring glycosyl groups
ABH19_RS09515	COG1012	belongs to the aldehyde dehydrogenase family
ABH19_RS09545	COG3002	Belongs to the UPF0753 family
ABH19_RS09555	COG0129	dihydroxy-acid dehydratase activity
ABH19_RS09560	COG0009	L-threonylcarbamoyladenylate synthase
ABH19_RS09565	COG0129	dihydroxy-acid dehydratase activity
ABH19_RS09580	COG3002	Belongs to the UPF0753 family
ABH19_RS09585	COG3852	Histidine kinase
ABH19_RS09590	COG2204	response regulator
ABH19_RS09705	COG0477	Major facilitator Superfamily
ABH19_RS09710	COG1902	pentaerythritol trinitrate reductase activity
ABH19_RS09715	COG0697	spore germination
ABH19_RS09720	COG0579	oxidoreductase
ABH19_RS09730	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ABH19_RS09735	COG3278	Belongs to the heme-copper respiratory oxidase family
ABH19_RS09760	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ABH19_RS09765	COG0671	phosphoesterase, PA-phosphatase related
ABH19_RS09785	COG0730	response to heat
ABH19_RS09800	COG5002	protein histidine kinase activity
ABH19_RS09800	COG0784	Response regulator, receiver
ABH19_RS09805	COG0739	heme binding
ABH19_RS09815	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ABH19_RS09825	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ABH19_RS09825	COG0517	IMP dehydrogenase activity
ABH19_RS09830	COG2877	3-deoxy-8-phosphooctulonate synthase activity
ABH19_RS09835	COG0504	CTP synthase activity
ABH19_RS09840	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
ABH19_RS09855	COG0481	GTPase activity
ABH19_RS09870	COG0124	histidyl-tRNA synthetase
ABH19_RS09880	COG2207	Transcriptional regulator
ABH19_RS09885	COG0667	Aldo Keto reductase
ABH19_RS09895	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ABH19_RS09900	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ABH19_RS09910	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ABH19_RS09915	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ABH19_RS09930	COG1793	dna ligase
ABH19_RS09960	COG0516	GMP reductase activity
ABH19_RS09960	COG0517	IMP dehydrogenase activity
ABH19_RS09965	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ABH19_RS09965	COG0519	Catalyzes the synthesis of GMP from XMP
ABH19_RS09970	COG1187	pseudouridine synthase activity
ABH19_RS09975	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ABH19_RS10010	COG0316	Belongs to the HesB IscA family
ABH19_RS10020	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ABH19_RS10025	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ABH19_RS10035	COG0505	Belongs to the CarA family
ABH19_RS10040	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ABH19_RS10045	COG0540	Belongs to the ATCase OTCase family
ABH19_RS10050	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
ABH19_RS10110	COG2379	hydroxypyruvate reductase
ABH19_RS10120	COG0616	signal peptide processing
ABH19_RS10125	COG1666	GTP binding
ABH19_RS10165	COG0493	'glutamate synthase
ABH19_RS10165	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ABH19_RS10175	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ABH19_RS10185	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ABH19_RS10195	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ABH19_RS10200	COG0159	tryptophan synthase activity
ABH19_RS10210	COG0135	phosphoribosylanthranilate isomerase activity
ABH19_RS10220	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ABH19_RS10225	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ABH19_RS10225	COG0512	Glutamine amidotransferase of anthranilate synthase
ABH19_RS10335	COG0083	homoserine kinase activity
ABH19_RS10345	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
ABH19_RS10355	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
ABH19_RS10365	COG4122	O-methyltransferase activity
ABH19_RS10370	COG1222	aaa ATPase
ABH19_RS10380	COG0778	Nitroreductase
ABH19_RS10385	COG1509	lysine 2,3-aminomutase activity
ABH19_RS10405	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ABH19_RS10410	COG0181	hydroxymethylbilane synthase activity
ABH19_RS10425	COG0113	porphobilinogen synthase activity
ABH19_RS10430	COG0196	riboflavin kinase activity
ABH19_RS10440	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
ABH19_RS10445	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ABH19_RS10450	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ABH19_RS10455	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
ABH19_RS10470	COG3180	Ammonia monooxygenase
ABH19_RS10475	COG1335	isochorismatase
ABH19_RS10485	COG0025	NhaP-type Na H and K H
ABH19_RS10515	COG1566	PFAM secretion protein HlyD family protein
ABH19_RS10535	COG0415	Belongs to the DNA photolyase family
ABH19_RS10540	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ABH19_RS10565	COG0582	viral genome integration into host DNA
ABH19_RS10575	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ABH19_RS10615	COG3657	addiction module killer protein
ABH19_RS10620	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ABH19_RS10800	COG3437	response regulator, receiver
ABH19_RS10830	COG0582	viral genome integration into host DNA
ABH19_RS10840	COG3077	Addiction module antitoxin, RelB DinJ family
ABH19_RS10860	COG0811	peptide transport
ABH19_RS10865	COG0848	biopolymer transport protein
ABH19_RS10880	COG0745	RESPONSE REGULATOR receiver
ABH19_RS10895	COG1074	ATP-dependent DNA helicase activity
ABH19_RS10900	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
ABH19_RS10940	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ABH19_RS10955	COG3447	MASE1 domain protein
ABH19_RS10955	COG5001	Diguanylate cyclase
ABH19_RS10955	COG5002	protein histidine kinase activity
ABH19_RS10995	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ABH19_RS11000	COG1959	2 iron, 2 sulfur cluster binding
ABH19_RS11005	COG1902	pentaerythritol trinitrate reductase activity
ABH19_RS11055	COG2204	response regulator
ABH19_RS11080	COG0148	phosphopyruvate hydratase activity
ABH19_RS11095	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ABH19_RS11100	COG0154	amidase activity
ABH19_RS11105	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ABH19_RS11110	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ABH19_RS11115	COG0210	DNA helicase
ABH19_RS11125	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ABH19_RS11155	COG0640	Transcriptional regulator
ABH19_RS11165	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ABH19_RS11180	COG1846	Transcriptional regulator
ABH19_RS11185	COG0235	Class ii aldolase
ABH19_RS11205	COG0450	alkyl hydroperoxide reductase
ABH19_RS11210	COG1858	cytochrome C peroxidase
ABH19_RS11220	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ABH19_RS11225	COG0470	DNA polymerase III
ABH19_RS11230	COG1774	PSP1 C-terminal conserved region
ABH19_RS11235	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ABH19_RS11235	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ABH19_RS11240	COG0084	hydrolase, TatD family'
ABH19_RS11255	COG0531	amino acid
ABH19_RS11275	COG0531	amino acid
ABH19_RS11280	COG1252	NADH dehydrogenase
ABH19_RS11300	COG1160	GTP binding
ABH19_RS11305	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ABH19_RS11305	COG0574	Belongs to the PEP-utilizing enzyme family
ABH19_RS11355	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
ABH19_RS11405	COG0582	viral genome integration into host DNA
ABH19_RS11415	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ABH19_RS11420	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ABH19_RS11435	COG0571	ribonuclease III activity
ABH19_RS11440	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ABH19_RS11450	COG1028	Short-chain dehydrogenase reductase Sdr
ABH19_RS11460	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ABH19_RS11465	COG0416	fatty acid biosynthetic process
ABH19_RS11480	COG0442	prolyl-tRNA aminoacylation
ABH19_RS11485	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ABH19_RS11490	COG0750	zinc metalloprotease
ABH19_RS11505	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ABH19_RS11515	COG2759	Belongs to the formate--tetrahydrofolate ligase family
ABH19_RS11520	COG1968	undecaprenyl-diphosphatase activity
ABH19_RS11525	COG0805	protein transport
ABH19_RS11550	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ABH19_RS11565	COG0312	modulator of DNA gyrase
ABH19_RS11570	COG0312	modulator of DNA gyrase
ABH19_RS11585	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
ABH19_RS11590	COG1562	ergosterol biosynthetic process
ABH19_RS11600	COG1192	Involved in chromosome partitioning
ABH19_RS11610	COG1619	proteins homologs of microcin C7 resistance protein MccF
ABH19_RS11750	COG3657	addiction module killer protein
ABH19_RS11755	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ABH19_RS11790	COG3012	SEC-C Motif Domain Protein
ABH19_RS11830	COG3012	SEC-C Motif Domain Protein
ABH19_RS11875	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ABH19_RS11940	COG3012	SEC-C Motif Domain Protein
ABH19_RS12010	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ABH19_RS12015	COG0588	phosphoglycerate mutase activity
ABH19_RS12025	COG0513	Belongs to the DEAD box helicase family
ABH19_RS12030	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
ABH19_RS12050	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ABH19_RS12055	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ABH19_RS12065	COG0488	(ABC) transporter
ABH19_RS12080	COG1187	pseudouridine synthase activity
ABH19_RS12115	COG0358	DNA primase activity
ABH19_RS12135	COG0776	regulation of translation
ABH19_RS12140	COG0537	adenosine 5'-monophosphoramidase activity
ABH19_RS12150	COG0107	imidazoleglycerol-phosphate synthase activity
ABH19_RS12155	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ABH19_RS12170	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ABH19_RS12175	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ABH19_RS12180	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ABH19_RS12185	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ABH19_RS12190	COG2890	protein-(glutamine-N5) methyltransferase activity
ABH19_RS12195	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ABH19_RS12200	COG0254	rRNA binding
ABH19_RS12205	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ABH19_RS12220	COG0123	including yeast histone deacetylase and acetoin utilization protein
ABH19_RS12235	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
ABH19_RS12240	COG1012	belongs to the aldehyde dehydrogenase family
ABH19_RS12250	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
ABH19_RS12255	COG0704	Plays a role in the regulation of phosphate uptake
ABH19_RS12260	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ABH19_RS12265	COG0581	inorganic phosphate transmembrane transporter activity
ABH19_RS12275	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ABH19_RS12285	COG0745	RESPONSE REGULATOR receiver
ABH19_RS12305	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ABH19_RS12325	COG2003	Belongs to the UPF0758 family
ABH19_RS12350	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ABH19_RS12360	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
ABH19_RS12400	COG3002	Belongs to the UPF0753 family
ABH19_RS12430	COG1136	(ABC) transporter
ABH19_RS12430	COG0577	efflux transmembrane transporter activity
ABH19_RS12435	COG1136	(ABC) transporter
ABH19_RS12485	COG4641	Protein conserved in bacteria
ABH19_RS12510	COG1516	flagellar protein fliS
ABH19_RS12520	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ABH19_RS12525	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
ABH19_RS12540	COG1256	bacterial-type flagellum assembly
ABH19_RS12555	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ABH19_RS12565	COG1706	bacterial-type flagellum-dependent cell motility
ABH19_RS12585	COG4786	Flagellar basal body rod
ABH19_RS12595	COG0179	Fumarylacetoacetate (FAA) hydrolase
ABH19_RS12615	COG0019	diaminopimelate decarboxylase activity
ABH19_RS12620	COG0165	Argininosuccinate lyase
ABH19_RS12625	COG0137	argininosuccinate synthase activity
ABH19_RS12630	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ABH19_RS12635	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ABH19_RS12640	COG0475	glutathione-regulated potassium exporter activity
ABH19_RS12640	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ABH19_RS12645	COG2814	Major facilitator Superfamily
ABH19_RS12670	COG2226	methyltransferase
ABH19_RS12685	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ABH19_RS12690	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ABH19_RS12700	COG0698	ribose 5-phosphate isomerase
ABH19_RS12705	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ABH19_RS12710	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ABH19_RS12715	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ABH19_RS12730	COG0785	Cytochrome C biogenesis protein
ABH19_RS12735	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ABH19_RS12740	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ABH19_RS12745	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ABH19_RS12750	COG1333	cytochrome c biogenesis protein
ABH19_RS12760	COG1127	ABC transporter
ABH19_RS12765	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ABH19_RS12770	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ABH19_RS12775	COG0233	cytoplasmic translational termination
ABH19_RS12780	COG0528	UMP kinase activity
ABH19_RS12785	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ABH19_RS12790	COG0052	Belongs to the universal ribosomal protein uS2 family
ABH19_RS12795	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ABH19_RS12800	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ABH19_RS12805	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ABH19_RS12810	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ABH19_RS12815	COG1032	radical SAM domain protein
ABH19_RS12820	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ABH19_RS12840	COG1530	ribonuclease E activity
ABH19_RS12845	COG0772	Belongs to the SEDS family
ABH19_RS12850	COG0768	penicillin binding
ABH19_RS12865	COG1077	Cell shape determining protein MreB Mrl
ABH19_RS12875	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ABH19_RS12885	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ABH19_RS12890	COG0242	peptide deformylase activity
ABH19_RS12895	COG3328	transposase activity
ABH19_RS12910	COG1331	Highly conserved protein containing a thioredoxin domain
ABH19_RS12955	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ABH19_RS12985	COG1543	Belongs to the glycosyl hydrolase 57 family
ABH19_RS13000	COG1449	Belongs to the glycosyl hydrolase 57 family
ABH19_RS13010	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ABH19_RS13045	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ABH19_RS13065	COG0542	response to heat
ABH19_RS13085	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ABH19_RS13095	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ABH19_RS13125	COG1013	pyruvate-flavodoxin oxidoreductase activity
ABH19_RS13130	COG0674	pyruvate-flavodoxin oxidoreductase activity
ABH19_RS13150	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ABH19_RS13150	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ABH19_RS13150	COG1013	pyruvate-flavodoxin oxidoreductase activity
ABH19_RS13150	COG0674	pyruvate-flavodoxin oxidoreductase activity
ABH19_RS13170	COG0484	heat shock protein binding
ABH19_RS13185	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ABH19_RS13190	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ABH19_RS13195	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ABH19_RS13195	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
ABH19_RS13200	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ABH19_RS13210	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ABH19_RS13215	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ABH19_RS13220	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ABH19_RS13245	COG2855	membrane
ABH19_RS13270	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ABH19_RS13275	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ABH19_RS13285	COG0564	pseudouridine synthase activity
ABH19_RS13295	COG0142	geranyltranstransferase activity
ABH19_RS13320	COG1892	Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four- carbon dicarboxylic acid source for the tricarboxylic acid cycle
ABH19_RS13330	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
ABH19_RS13350	COG0425	Belongs to the sulfur carrier protein TusA family
ABH19_RS13355	COG0571	ribonuclease III activity
ABH19_RS13365	COG0482	sulfurtransferase activity
ABH19_RS13375	COG1475	DNA binding
ABH19_RS13385	COG0357	Ribosomal RNA small subunit methyltransferase G
ABH19_RS13390	COG0445	tRNA wobble uridine modification
ABH19_RS13395	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ABH19_RS13400	COG0706	membrane insertase activity
ABH19_RS13405	COG0359	binds to the 23S rRNA
ABH19_RS13425	COG1970	mechanosensitive ion channel activity
ABH19_RS13445	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
ABH19_RS13485	COG0284	orotidine-5'-phosphate decarboxylase activity
ABH19_RS13490	COG2264	protein methyltransferase activity
ABH19_RS13500	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ABH19_RS13500	COG0785	Cytochrome C biogenesis protein
ABH19_RS13525	COG1850	ribulose-bisphosphate carboxylase activity
ABH19_RS13530	COG1032	radical SAM domain protein
ABH19_RS13580	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ABH19_RS13585	COG0473	3-isopropylmalate dehydrogenase activity
ABH19_RS13590	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ABH19_RS13595	COG1183	phosphatidylcholine synthase activity
ABH19_RS13600	COG0688	phosphatidylethanolamine metabolic process
ABH19_RS13605	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ABH19_RS13610	COG0440	acetolactate synthase activity
ABH19_RS13615	COG0028	Belongs to the TPP enzyme family
ABH19_RS13635	COG1648	precorrin-2 dehydrogenase activity
ABH19_RS13635	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ABH19_RS13665	COG2003	Belongs to the UPF0758 family
ABH19_RS13680	COG0582	viral genome integration into host DNA
ABH19_RS13685	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ABH19_RS13690	COG2204	response regulator
ABH19_RS13705	COG4251	negative regulation of phosphorylation
ABH19_RS13710	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ABH19_RS13720	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ABH19_RS13725	COG0739	heme binding
ABH19_RS13730	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ABH19_RS13740	COG0494	nUDIX hydrolase
ABH19_RS13750	COG1472	Belongs to the glycosyl hydrolase 3 family