locus-tag	class	description
EVS81_RS00005	COG0484	heat shock protein binding
EVS81_RS00030	COG0577	efflux transmembrane transporter activity
EVS81_RS00030	COG1136	(ABC) transporter
EVS81_RS00035	COG1136	(ABC) transporter
EVS81_RS00040	COG0537	adenosine 5'-monophosphoramidase activity
EVS81_RS00050	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EVS81_RS00060	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EVS81_RS00085	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EVS81_RS00090	COG0632	four-way junction helicase activity
EVS81_RS00095	COG2255	four-way junction helicase activity
EVS81_RS00105	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EVS81_RS00110	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EVS81_RS00115	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EVS81_RS00125	COG1196	nuclear chromosome segregation
EVS81_RS00135	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EVS81_RS00145	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EVS81_RS00150	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EVS81_RS00155	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EVS81_RS00160	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EVS81_RS00165	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EVS81_RS00175	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EVS81_RS00180	COG0714	Associated with various cellular activities
EVS81_RS00210	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EVS81_RS00215	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EVS81_RS00220	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EVS81_RS00225	COG0540	Belongs to the ATCase OTCase family
EVS81_RS00230	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EVS81_RS00235	COG0505	Belongs to the CarA family
EVS81_RS00240	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EVS81_RS00245	COG0284	orotidine-5'-phosphate decarboxylase activity
EVS81_RS00250	COG0194	GDP metabolic process
EVS81_RS00265	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EVS81_RS00270	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EVS81_RS00275	COG1120	ATPase activity
EVS81_RS00285	COG2094	Belongs to the DNA glycosylase MPG family
EVS81_RS00300	COG3119	arylsulfatase activity
EVS81_RS00310	COG0386	Belongs to the glutathione peroxidase family
EVS81_RS00320	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EVS81_RS00325	COG3253	May function as heme-dependent peroxidase
EVS81_RS00330	COG0783	Belongs to the Dps family
EVS81_RS00340	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EVS81_RS00345	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EVS81_RS00350	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EVS81_RS00395	COG0435	Glutathione S-transferase
EVS81_RS00400	COG2814	Major facilitator Superfamily
EVS81_RS00405	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EVS81_RS00410	COG1472	Belongs to the glycosyl hydrolase 3 family
EVS81_RS00425	COG1464	Belongs to the NlpA lipoprotein family
EVS81_RS00430	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EVS81_RS00435	COG2011	ABC-type metal ion transport system permease component
EVS81_RS00470	COG0174	glutamine synthetase
EVS81_RS00475	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
EVS81_RS00480	COG0174	glutamine synthetase
EVS81_RS00495	COG0508	dehydrogenase complex catalyzes the overall conversion of
EVS81_RS00500	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EVS81_RS00510	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EVS81_RS00520	COG0187	DNA topoisomerase II activity
EVS81_RS00530	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EVS81_RS00555	COG0756	dUTP diphosphatase activity
EVS81_RS00570	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EVS81_RS00575	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EVS81_RS00580	COG1024	Enoyl-CoA hydratase
EVS81_RS00580	COG1250	3-hydroxyacyl-CoA dehydrogenase
EVS81_RS00585	COG0183	Belongs to the thiolase family
EVS81_RS00590	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
EVS81_RS00655	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EVS81_RS00665	COG0217	transcriptional regulatory protein
EVS81_RS00670	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EVS81_RS00675	COG2860	membrane
EVS81_RS00680	COG1381	Involved in DNA repair and RecF pathway recombination
EVS81_RS00685	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EVS81_RS00700	COG0358	DNA primase activity
EVS81_RS00705	COG4608	Belongs to the ABC transporter superfamily
EVS81_RS00730	COG0544	peptidyl-prolyl cis-trans isomerase activity
EVS81_RS00735	COG0740	serine-type endopeptidase activity
EVS81_RS00740	COG0740	serine-type endopeptidase activity
EVS81_RS00745	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EVS81_RS00760	COG0525	valine-tRNA ligase activity
EVS81_RS00765	COG0488	(ABC) transporter
EVS81_RS00775	COG4176	ABC-type proline glycine betaine transport system permease component
EVS81_RS00780	COG4175	Glycine betaine
EVS81_RS00780	COG0517	IMP dehydrogenase activity
EVS81_RS00785	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EVS81_RS00790	COG0285	dihydrofolate synthase activity
EVS81_RS00800	COG0105	UTP biosynthetic process
EVS81_RS00805	COG3214	Protein conserved in bacteria
EVS81_RS00820	COG0556	nucleotide-excision repair
EVS81_RS00850	COG0322	excinuclease ABC activity
EVS81_RS00855	COG1660	Displays ATPase and GTPase activities
EVS81_RS00860	COG1481	regulation of sporulation
EVS81_RS00870	COG0126	phosphoglycerate kinase activity
EVS81_RS00875	COG0149	triose-phosphate isomerase activity
EVS81_RS00880	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EVS81_RS00905	COG0166	Belongs to the GPI family
EVS81_RS00910	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EVS81_RS00920	COG0109	protoheme IX farnesyltransferase activity
EVS81_RS00925	COG2226	methyltransferase
EVS81_RS00960	COG0396	ATPase activity
EVS81_RS00965	COG2151	metal-sulfur cluster biosynthetic enzyme
EVS81_RS00980	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EVS81_RS00985	COG0363	glucosamine-6-phosphate deaminase activity
EVS81_RS00990	COG0488	(ABC) transporter
EVS81_RS01020	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EVS81_RS01025	COG0560	Phosphoserine phosphatase
EVS81_RS01030	COG1119	ATPase activity
EVS81_RS01035	COG0254	rRNA binding
EVS81_RS01060	COG0135	phosphoribosylanthranilate isomerase activity
EVS81_RS01065	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EVS81_RS01075	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EVS81_RS01080	COG1845	cytochrome c oxidase, subunit III
EVS81_RS01085	COG2010	Cytochrome c
EVS81_RS01090	COG0723	plastoquinol--plastocyanin reductase activity
EVS81_RS01095	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EVS81_RS01115	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EVS81_RS01120	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EVS81_RS01135	COG0167	dihydroorotate dehydrogenase activity
EVS81_RS01140	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EVS81_RS01145	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EVS81_RS01150	COG2890	protein-(glutamine-N5) methyltransferase activity
EVS81_RS01165	COG0067	glutamate synthase
EVS81_RS01165	COG0069	glutamate synthase activity
EVS81_RS01165	COG0070	glutamate synthase
EVS81_RS01185	COG4581	dead DEAH box helicase
EVS81_RS01190	COG0805	protein transport
EVS81_RS01220	COG0215	cysteine-tRNA ligase activity
EVS81_RS01225	COG1968	undecaprenyl-diphosphatase activity
EVS81_RS01230	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EVS81_RS01255	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EVS81_RS01265	COG0668	transmembrane transport
EVS81_RS01275	COG1280	lysine exporter protein (LysE YggA)
EVS81_RS01290	COG0477	Major facilitator Superfamily
EVS81_RS01295	COG0242	peptide deformylase activity
EVS81_RS01300	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
EVS81_RS01310	COG5001	Diguanylate cyclase
EVS81_RS01365	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EVS81_RS01370	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EVS81_RS01375	COG0730	response to heat
EVS81_RS01405	COG2409	Drug exporters of the RND superfamily
EVS81_RS01420	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EVS81_RS01475	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EVS81_RS01510	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EVS81_RS01535	COG0477	Major facilitator Superfamily
EVS81_RS01555	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EVS81_RS01670	COG0739	heme binding
EVS81_RS01670	COG1196	nuclear chromosome segregation
EVS81_RS01670	COG0741	lytic transglycosylase activity
EVS81_RS01760	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EVS81_RS01770	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EVS81_RS01780	COG0395	ABC-type sugar transport system, permease component
EVS81_RS01785	COG1175	transmembrane transport
EVS81_RS01795	COG1414	Transcriptional regulator
EVS81_RS01810	COG0129	dihydroxy-acid dehydratase activity
EVS81_RS01815	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EVS81_RS01820	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EVS81_RS01825	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EVS81_RS01830	COG0154	amidase activity
EVS81_RS01835	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EVS81_RS01840	COG0519	Catalyzes the synthesis of GMP from XMP
EVS81_RS01845	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EVS81_RS01850	COG0482	sulfurtransferase activity
EVS81_RS01875	COG0328	RNA-DNA hybrid ribonuclease activity
EVS81_RS01900	COG0233	cytoplasmic translational termination
EVS81_RS01905	COG0528	UMP kinase activity
EVS81_RS01910	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EVS81_RS01915	COG0052	Belongs to the universal ribosomal protein uS2 family
EVS81_RS01920	COG0792	nuclease activity
EVS81_RS01935	COG4974	Belongs to the 'phage' integrase family
EVS81_RS01960	COG0587	DNA-directed DNA polymerase activity
EVS81_RS01980	COG1131	(ABC) transporter
EVS81_RS02005	COG0300	oxidoreductase activity
EVS81_RS02010	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EVS81_RS02015	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EVS81_RS02030	COG1615	UPF0182 protein
EVS81_RS02035	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EVS81_RS02050	COG0210	DNA helicase
EVS81_RS02065	COG0584	glycerophosphoryl diester phosphodiesterase
EVS81_RS02070	COG0210	DNA helicase
EVS81_RS02090	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EVS81_RS02100	COG0513	Belongs to the DEAD box helicase family
EVS81_RS02110	COG0006	proline dipeptidase activity
EVS81_RS02120	COG3012	SEC-C Motif Domain Protein
EVS81_RS02135	COG1982	Orn Lys Arg decarboxylase major
EVS81_RS02145	COG2814	Major facilitator Superfamily
EVS81_RS02155	COG0765	amino acid transport
EVS81_RS02165	COG0402	S-adenosylhomocysteine deaminase activity
EVS81_RS02170	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
EVS81_RS02190	COG2076	Multidrug Resistance protein
EVS81_RS02195	COG2076	Multidrug Resistance protein
EVS81_RS02205	COG3189	MarR family transcriptional regulator
EVS81_RS02210	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EVS81_RS02220	COG2189	Belongs to the N(4) N(6)-methyltransferase family
EVS81_RS02225	COG1024	Enoyl-CoA hydratase
EVS81_RS02255	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EVS81_RS02255	COG0596	Alpha beta hydrolase
EVS81_RS02260	COG0747	negative chemotaxis
EVS81_RS02265	COG2365	Tyrosine phosphatase family
EVS81_RS02285	COG1162	GTPase activity
EVS81_RS02305	COG0137	argininosuccinate synthase activity
EVS81_RS02315	COG0039	L-malate dehydrogenase activity
EVS81_RS02340	COG1643	Atp-dependent helicase
EVS81_RS02355	COG2239	Acts as a magnesium transporter
EVS81_RS02390	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EVS81_RS02395	COG2171	N-acyltransferase activity
EVS81_RS02430	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EVS81_RS02435	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EVS81_RS02440	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EVS81_RS02445	COG1024	Enoyl-CoA hydratase
EVS81_RS02455	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EVS81_RS02460	COG2079	MmgE PrpD family protein
EVS81_RS02495	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EVS81_RS02495	COG0072	phenylalanine-tRNA ligase activity
EVS81_RS02500	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EVS81_RS02505	COG1984	allophanate hydrolase subunit 2
EVS81_RS02510	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EVS81_RS02530	COG2837	iron assimilation
EVS81_RS02535	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EVS81_RS02540	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EVS81_RS02545	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EVS81_RS02550	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EVS81_RS02560	COG0667	Aldo Keto reductase
EVS81_RS02565	COG1522	sequence-specific DNA binding
EVS81_RS02570	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
EVS81_RS02585	COG0733	neurotransmitter:sodium symporter activity
EVS81_RS02595	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EVS81_RS02600	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EVS81_RS02605	COG0131	Imidazoleglycerol-phosphate dehydratase
EVS81_RS02610	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EVS81_RS02635	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EVS81_RS02640	COG0321	lipoyl(octanoyl) transferase activity
EVS81_RS02645	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EVS81_RS02650	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EVS81_RS02660	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EVS81_RS02665	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EVS81_RS02670	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EVS81_RS02695	COG0714	Associated with various cellular activities
EVS81_RS02700	COG2813	Specifically methylates the guanine in position
EVS81_RS02705	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EVS81_RS02710	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EVS81_RS02715	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EVS81_RS02720	COG2137	regulation of response to DNA damage stimulus
EVS81_RS02725	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EVS81_RS02735	COG1396	sequence-specific DNA binding
EVS81_RS02750	COG1674	ftsk spoiiie
EVS81_RS02765	COG2348	transferase activity, transferring amino-acyl groups
EVS81_RS02770	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EVS81_RS02775	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EVS81_RS02785	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EVS81_RS02805	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EVS81_RS02810	COG0612	Peptidase, M16
EVS81_RS02815	COG1185	polyribonucleotide nucleotidyltransferase activity
EVS81_RS02840	COG1643	Atp-dependent helicase
EVS81_RS02865	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EVS81_RS02880	COG0129	dihydroxy-acid dehydratase activity
EVS81_RS02895	COG0483	inositol monophosphate 1-phosphatase activity
EVS81_RS02930	COG0300	oxidoreductase activity
EVS81_RS02935	COG1028	Short-chain dehydrogenase reductase Sdr
EVS81_RS02970	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EVS81_RS02975	COG2177	Part of the ABC transporter FtsEX involved in
EVS81_RS02980	COG2884	Cell division ATP-binding protein ftsE
EVS81_RS02985	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EVS81_RS02990	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EVS81_RS03005	COG0531	amino acid
EVS81_RS03015	COG1176	ABC-type spermidine putrescine transport system, permease component I
EVS81_RS03020	COG3842	ATPase activity
EVS81_RS03035	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EVS81_RS03045	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EVS81_RS03070	COG0746	molybdenum cofactor guanylyltransferase activity
EVS81_RS03080	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EVS81_RS03105	COG3585	molybdate ion transport
EVS81_RS03125	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EVS81_RS03130	COG0314	molybdopterin synthase activity
EVS81_RS03160	COG0521	Mo-molybdopterin cofactor biosynthetic process
EVS81_RS03160	COG0315	cyclic pyranopterin monophosphate synthase activity
EVS81_RS03165	COG2252	PERMEase
EVS81_RS03170	COG0545	Peptidyl-prolyl cis-trans isomerase
EVS81_RS03175	COG0179	Fumarylacetoacetate (FAA) hydrolase
EVS81_RS03180	COG1027	Aspartate ammonia-lyase
EVS81_RS03185	COG2814	Major facilitator Superfamily
EVS81_RS03195	COG1704	LemA family
EVS81_RS03215	COG2135	peptidase activity
EVS81_RS03225	COG2271	Major facilitator Superfamily
EVS81_RS03230	COG0583	DNA-binding transcription factor activity
EVS81_RS03245	COG1917	Cupin 2, conserved barrel domain protein
EVS81_RS03260	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EVS81_RS03265	COG4569	acetaldehyde dehydrogenase (acetylating) activity
EVS81_RS03280	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
EVS81_RS03290	COG1252	NADH dehydrogenase
EVS81_RS03305	COG0148	phosphopyruvate hydratase activity
EVS81_RS03315	COG0124	histidyl-tRNA synthetase
EVS81_RS03330	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EVS81_RS03345	COG2197	response regulator
EVS81_RS03355	COG3956	TIGRFAM MazG family protein
EVS81_RS03370	COG0193	aminoacyl-tRNA hydrolase activity
EVS81_RS03375	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EVS81_RS03395	COG0010	Belongs to the arginase family
EVS81_RS03400	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EVS81_RS03410	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EVS81_RS03440	COG1136	(ABC) transporter
EVS81_RS03440	COG0577	efflux transmembrane transporter activity
EVS81_RS03450	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EVS81_RS03455	COG0702	epimerase
EVS81_RS03475	COG0508	dehydrogenase complex catalyzes the overall conversion of
EVS81_RS03475	COG0567	Dehydrogenase, E1 component
EVS81_RS03500	COG0519	Catalyzes the synthesis of GMP from XMP
EVS81_RS03510	COG0174	glutamine synthetase
EVS81_RS03515	COG2124	cytochrome p450
EVS81_RS03535	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EVS81_RS03555	COG2957	Belongs to the agmatine deiminase family
EVS81_RS03575	COG1136	(ABC) transporter
EVS81_RS03600	COG0138	bifunctional purine biosynthesis protein purh
EVS81_RS03640	COG1090	epimerase
EVS81_RS03650	COG0045	succinate-CoA ligase (ADP-forming) activity
EVS81_RS03675	COG0252	asparaginase activity
EVS81_RS03685	COG1136	(ABC) transporter
EVS81_RS03685	COG0577	efflux transmembrane transporter activity
EVS81_RS03690	COG1136	(ABC) transporter
EVS81_RS03695	COG0584	glycerophosphoryl diester phosphodiesterase
EVS81_RS03715	COG0519	Catalyzes the synthesis of GMP from XMP
EVS81_RS03715	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EVS81_RS03745	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EVS81_RS03770	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EVS81_RS03775	COG1214	PFAM Peptidase M22, glycoprotease
EVS81_RS03775	COG0456	acetyltransferase
EVS81_RS03785	COG0802	atpase or kinase
EVS81_RS03790	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EVS81_RS03795	COG0736	holo-[acyl-carrier-protein] synthase activity
EVS81_RS03800	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EVS81_RS03805	COG1072	(Pantothenic acid kinase))
EVS81_RS03815	COG1228	amidohydrolase
EVS81_RS03830	COG1129	ABC transporter
EVS81_RS03835	COG1172	Belongs to the binding-protein-dependent transport system permease family
EVS81_RS03920	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EVS81_RS03940	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EVS81_RS03950	COG1116	anion transmembrane transporter activity
EVS81_RS03950	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EVS81_RS03960	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EVS81_RS03965	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EVS81_RS03970	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EVS81_RS03975	COG0101	tRNA pseudouridine synthase activity
EVS81_RS03980	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EVS81_RS03980	COG2755	lipolytic protein G-D-S-L family
EVS81_RS03985	COG0203	ribosomal protein L17
EVS81_RS03990	COG0202	RNA polymerase activity
EVS81_RS03995	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EVS81_RS04000	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EVS81_RS04010	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EVS81_RS04020	COG0563	adenylate kinase activity
EVS81_RS04030	COG0200	Binds to the 23S rRNA
EVS81_RS04035	COG1841	ribosomal large subunit assembly
EVS81_RS04040	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EVS81_RS04045	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EVS81_RS04050	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EVS81_RS04055	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EVS81_RS04060	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EVS81_RS04065	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EVS81_RS04070	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EVS81_RS04075	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EVS81_RS04080	COG0255	Belongs to the universal ribosomal protein uL29 family
EVS81_RS04085	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EVS81_RS04090	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EVS81_RS04095	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EVS81_RS04100	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EVS81_RS04105	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EVS81_RS04110	COG0089	rRNA binding
EVS81_RS04115	COG0088	Forms part of the polypeptide exit tunnel
EVS81_RS04120	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EVS81_RS04125	COG0051	transcription antitermination factor activity, RNA binding
EVS81_RS04140	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EVS81_RS04145	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EVS81_RS04150	COG0049	tRNA binding
EVS81_RS04155	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EVS81_RS04175	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EVS81_RS04180	COG0085	RNA polymerase activity
EVS81_RS04205	COG2514	catechol 2,3-dioxygenase activity
EVS81_RS04225	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EVS81_RS04240	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EVS81_RS04270	COG1174	glycine betaine transport
EVS81_RS04275	COG1174	glycine betaine transport
EVS81_RS04280	COG0517	IMP dehydrogenase activity
EVS81_RS04280	COG1125	glycine betaine transport
EVS81_RS04285	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EVS81_RS04310	COG3425	synthase
EVS81_RS04350	COG0402	S-adenosylhomocysteine deaminase activity
EVS81_RS04355	COG0477	Major facilitator Superfamily
EVS81_RS04385	COG0693	protein deglycase activity
EVS81_RS04425	COG2197	response regulator
EVS81_RS04435	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EVS81_RS04445	COG0083	homoserine kinase activity
EVS81_RS04450	COG0460	homoserine dehydrogenase
EVS81_RS04460	COG0531	amino acid
EVS81_RS04470	COG2508	Transcriptional regulator
EVS81_RS04480	COG0018	arginyl-trna synthetase
EVS81_RS04505	COG0477	Major facilitator Superfamily
EVS81_RS04510	COG0509	glycine decarboxylation via glycine cleavage system
EVS81_RS04515	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EVS81_RS04520	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EVS81_RS04520	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EVS81_RS04535	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EVS81_RS04540	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EVS81_RS04550	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EVS81_RS04555	COG0583	DNA-binding transcription factor activity
EVS81_RS04565	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EVS81_RS04570	COG0154	amidase activity
EVS81_RS04575	COG1611	Belongs to the LOG family
EVS81_RS04585	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EVS81_RS04590	COG0750	zinc metalloprotease
EVS81_RS04595	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EVS81_RS04630	COG0822	iron-sulfur transferase activity
EVS81_RS04640	COG0583	DNA-binding transcription factor activity
EVS81_RS04645	COG1053	succinate dehydrogenase
EVS81_RS04655	COG1104	cysteine desulfurase activity
EVS81_RS04665	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EVS81_RS04670	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EVS81_RS04680	COG1278	Cold shock
EVS81_RS04685	COG0446	pyridine nucleotide-disulphide oxidoreductase
EVS81_RS04685	COG1902	pentaerythritol trinitrate reductase activity
EVS81_RS04690	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EVS81_RS04705	COG0747	negative chemotaxis
EVS81_RS04710	COG0601	transmembrane transport
EVS81_RS04715	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EVS81_RS04720	COG4172	Belongs to the ABC transporter superfamily
EVS81_RS04750	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
EVS81_RS04780	COG1253	flavin adenine dinucleotide binding
EVS81_RS04795	COG1937	Protein conserved in bacteria
EVS81_RS04805	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
EVS81_RS04870	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EVS81_RS04870	COG0758	DNA mediated transformation
EVS81_RS04910	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EVS81_RS04925	COG0436	Aminotransferase
EVS81_RS04935	COG0686	Belongs to the AlaDH PNT family
EVS81_RS04940	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EVS81_RS04945	COG1012	belongs to the aldehyde dehydrogenase family
EVS81_RS04955	COG0512	Glutamine amidotransferase of anthranilate synthase
EVS81_RS04965	COG1028	Short-chain dehydrogenase reductase Sdr
EVS81_RS04970	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EVS81_RS04975	COG2124	cytochrome p450
EVS81_RS05025	COG1196	nuclear chromosome segregation
EVS81_RS05025	COG0741	lytic transglycosylase activity
EVS81_RS05025	COG0739	heme binding
EVS81_RS05120	COG1725	Transcriptional regulator
EVS81_RS05145	COG0444	Belongs to the ABC transporter superfamily
EVS81_RS05150	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EVS81_RS05155	COG0601	transmembrane transport
EVS81_RS05165	COG1609	Transcriptional regulator
EVS81_RS05180	COG4608	Belongs to the ABC transporter superfamily
EVS81_RS05185	COG0444	Belongs to the ABC transporter superfamily
EVS81_RS05190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EVS81_RS05195	COG0601	transmembrane transport
EVS81_RS05205	COG1609	Transcriptional regulator
EVS81_RS05210	COG1217	gtp-binding protein TYPA
EVS81_RS05215	COG2814	Major facilitator Superfamily
EVS81_RS05225	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EVS81_RS05230	COG0601	transmembrane transport
EVS81_RS05260	COG2357	RelA SpoT domain protein
EVS81_RS05285	COG0596	Alpha beta hydrolase
EVS81_RS05305	COG0012	GTP binding
EVS81_RS05335	COG1494	fructose-1,6-bisphosphatase
EVS81_RS05340	COG0191	fructose-bisphosphate aldolase activity
EVS81_RS05360	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EVS81_RS05365	COG1570	exodeoxyribonuclease VII activity
EVS81_RS05370	COG1722	exodeoxyribonuclease VII activity
EVS81_RS05385	COG0114	fumarate hydratase activity
EVS81_RS05390	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EVS81_RS05395	COG0235	Class ii aldolase
EVS81_RS05395	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EVS81_RS05405	COG3845	ABC transporter
EVS81_RS05415	COG1079	Belongs to the binding-protein-dependent transport system permease family
EVS81_RS05440	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EVS81_RS05445	COG1960	acyl-CoA dehydrogenase activity
EVS81_RS05485	COG4166	transmembrane transport
EVS81_RS05495	COG4171	peptide transport system, permease
EVS81_RS05515	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
EVS81_RS05535	COG3655	Transcriptional regulator
EVS81_RS05565	COG3842	ATPase activity
EVS81_RS05570	COG0406	alpha-ribazole phosphatase activity
EVS81_RS05585	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EVS81_RS05595	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EVS81_RS05620	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EVS81_RS05625	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EVS81_RS05630	COG0302	gtp cyclohydrolase
EVS81_RS05635	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EVS81_RS05645	COG0037	tRNA processing
EVS81_RS05650	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EVS81_RS05670	COG1522	sequence-specific DNA binding
EVS81_RS05680	COG2186	Transcriptional regulator
EVS81_RS05685	COG0747	negative chemotaxis
EVS81_RS05690	COG0601	transmembrane transport
EVS81_RS05695	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EVS81_RS05705	COG0154	amidase activity
EVS81_RS05720	COG1028	Short-chain dehydrogenase reductase Sdr
EVS81_RS05725	COG1012	belongs to the aldehyde dehydrogenase family
EVS81_RS05730	COG0473	3-isopropylmalate dehydrogenase activity
EVS81_RS05735	COG0477	Major facilitator Superfamily
EVS81_RS05785	COG1609	Transcriptional regulator
EVS81_RS05790	COG4829	muconolactone delta-isomerase
EVS81_RS05805	COG1012	belongs to the aldehyde dehydrogenase family
EVS81_RS05810	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EVS81_RS05815	COG1116	anion transmembrane transporter activity
EVS81_RS05815	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EVS81_RS05830	COG2514	catechol 2,3-dioxygenase activity
EVS81_RS05870	COG2814	Major facilitator Superfamily
EVS81_RS05910	COG4106	trans-aconitate 2-methyltransferase activity
EVS81_RS05915	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EVS81_RS05930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EVS81_RS05940	COG1126	abc transporter atp-binding protein
EVS81_RS05955	COG3328	transposase activity
EVS81_RS05995	COG3328	transposase activity
EVS81_RS06075	COG0464	growth
EVS81_RS06095	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EVS81_RS06105	COG2409	Drug exporters of the RND superfamily
EVS81_RS06115	COG0477	Major facilitator Superfamily
EVS81_RS06125	COG4977	sequence-specific DNA binding
EVS81_RS06165	COG0741	lytic transglycosylase activity
EVS81_RS06165	COG0739	heme binding
EVS81_RS06165	COG1196	nuclear chromosome segregation
EVS81_RS06205	COG1247	-acetyltransferase
EVS81_RS06235	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EVS81_RS06240	COG0640	Transcriptional regulator
EVS81_RS06250	COG0798	PFAM Bile acid sodium symporter
EVS81_RS06255	COG3118	belongs to the thioredoxin family
EVS81_RS06260	COG0492	ferredoxin-NADP+ reductase activity
EVS81_RS06275	COG4974	Belongs to the 'phage' integrase family
EVS81_RS06330	COG4941	Belongs to the sigma-70 factor family
EVS81_RS06375	COG3739	integral membrane protein
EVS81_RS06380	COG1160	GTP binding
EVS81_RS06385	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EVS81_RS06395	COG1187	pseudouridine synthase activity
EVS81_RS06400	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EVS81_RS06405	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EVS81_RS06440	COG0497	DNA recombination
EVS81_RS06445	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EVS81_RS06465	COG0647	UMP catabolic process
EVS81_RS06495	COG1953	Uracil, thiamine, allantoin
EVS81_RS06510	COG1396	sequence-specific DNA binding
EVS81_RS06515	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
EVS81_RS06530	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EVS81_RS06535	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EVS81_RS06540	COG5401	PFAM Sporulation and spore germination
EVS81_RS06545	COG5002	protein histidine kinase activity
EVS81_RS06545	COG5000	phosphorelay sensor kinase activity
EVS81_RS06580	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EVS81_RS06585	COG1194	a g-specific adenine glycosylase
EVS81_RS06590	COG2197	response regulator
EVS81_RS06605	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EVS81_RS06620	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EVS81_RS06635	COG1674	ftsk spoiiie
EVS81_RS06660	COG0442	prolyl-tRNA aminoacylation
EVS81_RS06670	COG2197	response regulator
EVS81_RS06700	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EVS81_RS06705	COG0215	cysteine-tRNA ligase activity
EVS81_RS06715	COG5002	protein histidine kinase activity
EVS81_RS06735	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EVS81_RS06735	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EVS81_RS06740	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EVS81_RS06740	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EVS81_RS06745	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EVS81_RS06755	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EVS81_RS06760	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EVS81_RS06775	COG0151	Belongs to the GarS family
EVS81_RS06785	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EVS81_RS06795	COG0047	phosphoribosylformylglycinamidine synthase activity
EVS81_RS06800	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EVS81_RS06805	COG0113	porphobilinogen synthase activity
EVS81_RS06810	COG0181	hydroxymethylbilane synthase activity
EVS81_RS06820	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EVS81_RS06825	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EVS81_RS06860	COG0454	-acetyltransferase
EVS81_RS06860	COG0456	acetyltransferase
EVS81_RS06875	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EVS81_RS06885	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EVS81_RS06890	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EVS81_RS06890	COG1754	DNA topoisomerase type I activity
EVS81_RS06920	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EVS81_RS06935	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EVS81_RS06940	COG1408	metallophosphoesterase
EVS81_RS06965	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EVS81_RS06975	COG1522	sequence-specific DNA binding
EVS81_RS06990	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EVS81_RS06995	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EVS81_RS07000	COG3842	ATPase activity
EVS81_RS07005	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EVS81_RS07010	COG1177	transmembrane transport
EVS81_RS07015	COG1176	ABC-type spermidine putrescine transport system, permease component I
EVS81_RS07020	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EVS81_RS07050	COG0222	ribosome binding
EVS81_RS07055	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EVS81_RS07060	COG0745	RESPONSE REGULATOR receiver
EVS81_RS07095	COG0747	negative chemotaxis
EVS81_RS07100	COG1228	amidohydrolase
EVS81_RS07120	COG0363	glucosamine-6-phosphate deaminase activity
EVS81_RS07125	COG3842	ATPase activity
EVS81_RS07140	COG2182	Extracellular solute-binding protein
EVS81_RS07145	COG1175	transmembrane transport
EVS81_RS07150	COG0395	ABC-type sugar transport system, permease component
EVS81_RS07155	COG1472	Belongs to the glycosyl hydrolase 3 family
EVS81_RS07160	COG1940	carbohydrate kinase activity
EVS81_RS07170	COG2962	Rard protein
EVS81_RS07175	COG1937	Protein conserved in bacteria
EVS81_RS07200	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EVS81_RS07215	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EVS81_RS07235	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EVS81_RS07240	COG1316	TRANSCRIPTIONal
EVS81_RS07250	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EVS81_RS07260	COG3253	May function as heme-dependent peroxidase
EVS81_RS07270	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EVS81_RS07305	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EVS81_RS07330	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EVS81_RS07335	COG0586	Pfam SNARE associated Golgi protein
EVS81_RS07340	COG2909	trisaccharide binding
EVS81_RS07350	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EVS81_RS07355	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EVS81_RS07370	COG1574	metal-dependent hydrolase with the TIM-barrel fold
EVS81_RS07375	COG0531	amino acid
EVS81_RS07385	COG0531	amino acid
EVS81_RS07390	COG1574	metal-dependent hydrolase with the TIM-barrel fold
EVS81_RS07405	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EVS81_RS07425	COG0232	Belongs to the dGTPase family. Type 2 subfamily
EVS81_RS07435	COG1597	lipid kinase activity
EVS81_RS07455	COG0569	domain protein
EVS81_RS07455	COG0189	ligase activity
EVS81_RS07460	COG4067	protein conserved in archaea
EVS81_RS07460	COG0189	ligase activity
EVS81_RS07470	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EVS81_RS07480	COG0659	secondary active sulfate transmembrane transporter activity
EVS81_RS07490	COG2873	o-acetylhomoserine
EVS81_RS07495	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EVS81_RS07500	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EVS81_RS07510	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EVS81_RS07520	COG2030	dehydratase
EVS81_RS07525	COG4770	biotin carboxylase activity
EVS81_RS07535	COG0477	Major facilitator Superfamily
EVS81_RS07545	COG0017	Asparaginyl-tRNA synthetase
EVS81_RS07555	COG0492	ferredoxin-NADP+ reductase activity
EVS81_RS07560	COG1396	sequence-specific DNA binding
EVS81_RS07585	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EVS81_RS07605	COG4221	oxidoreductase activity
EVS81_RS07610	COG2409	Drug exporters of the RND superfamily
EVS81_RS07625	COG1233	COG1233 Phytoene dehydrogenase and related
EVS81_RS07635	COG0142	geranyltranstransferase activity
EVS81_RS07655	COG1316	TRANSCRIPTIONal
EVS81_RS07660	COG2197	response regulator
EVS81_RS07680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EVS81_RS07685	COG0765	amino acid transport
EVS81_RS07690	COG1126	abc transporter atp-binding protein
EVS81_RS07700	COG0180	Tryptophanyl-tRNA synthetase
EVS81_RS07705	COG1064	alcohol dehydrogenase
EVS81_RS07710	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EVS81_RS07730	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EVS81_RS07730	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EVS81_RS07735	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EVS81_RS07740	COG1132	(ABC) transporter
EVS81_RS07755	COG3594	Acyltransferase
EVS81_RS07765	COG4974	Belongs to the 'phage' integrase family
EVS81_RS07915	COG0470	DNA polymerase III
EVS81_RS07920	COG1739	Uncharacterized protein family UPF0029
EVS81_RS07935	COG0444	Belongs to the ABC transporter superfamily
EVS81_RS07950	COG1473	amidohydrolase
EVS81_RS07955	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EVS81_RS07980	COG1605	Chorismate mutase
EVS81_RS07980	COG0287	Prephenate dehydrogenase
EVS81_RS07985	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EVS81_RS07995	COG1666	GTP binding
EVS81_RS08015	COG1131	(ABC) transporter
EVS81_RS08030	COG2197	response regulator
EVS81_RS08035	COG4585	Histidine kinase
EVS81_RS08045	COG1131	(ABC) transporter
EVS81_RS08060	COG0604	alcohol dehydrogenase
EVS81_RS08115	COG0423	glycine-tRNA ligase activity
EVS81_RS08195	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EVS81_RS08205	COG0644	oxidoreductase
EVS81_RS08215	COG2188	Transcriptional regulator
EVS81_RS08235	COG1054	Belongs to the UPF0176 family
EVS81_RS08240	COG0640	Transcriptional regulator
EVS81_RS08250	COG3590	peptidase
EVS81_RS08255	COG3177	Filamentation induced by cAMP protein fic
EVS81_RS08270	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
EVS81_RS08290	COG1268	BioY protein
EVS81_RS08295	COG1122	ATPase activity
EVS81_RS08325	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EVS81_RS08330	COG0439	Biotin carboxylase
EVS81_RS08335	COG0511	ligase activity, forming carbon-carbon bonds
EVS81_RS08345	COG3835	regulator
EVS81_RS08365	COG2508	Transcriptional regulator
EVS81_RS08385	COG0402	S-adenosylhomocysteine deaminase activity
EVS81_RS08390	COG4608	Belongs to the ABC transporter superfamily
EVS81_RS08400	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EVS81_RS08405	COG0601	transmembrane transport
EVS81_RS08410	COG4166	transmembrane transport
EVS81_RS08415	COG0402	S-adenosylhomocysteine deaminase activity
EVS81_RS08420	COG2186	Transcriptional regulator
EVS81_RS08430	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EVS81_RS08455	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EVS81_RS08455	COG2755	lipolytic protein G-D-S-L family
EVS81_RS08480	COG1121	(ABC) transporter
EVS81_RS08485	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EVS81_RS08490	COG1012	belongs to the aldehyde dehydrogenase family
EVS81_RS08500	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EVS81_RS08505	COG3483	tryptophan 2,3-dioxygenase activity
EVS81_RS08530	COG3842	ATPase activity
EVS81_RS08535	COG1176	ABC-type spermidine putrescine transport system, permease component I
EVS81_RS08540	COG1177	transmembrane transport
EVS81_RS08545	COG1840	ABC-type Fe3 transport system, periplasmic component
EVS81_RS08575	COG4942	peptidase
EVS81_RS08650	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EVS81_RS08660	COG2357	RelA SpoT domain protein
EVS81_RS08685	COG0582	viral genome integration into host DNA
EVS81_RS08690	COG0596	Alpha beta hydrolase
EVS81_RS08710	COG1716	ATPase activity
EVS81_RS08725	COG0768	penicillin binding
EVS81_RS08730	COG0515	serine threonine protein kinase
EVS81_RS08735	COG2815	serine threonine protein kinase
EVS81_RS08735	COG0515	serine threonine protein kinase
EVS81_RS08770	COG1051	belongs to the nudix hydrolase family
EVS81_RS08785	COG2201	protein-glutamate methylesterase activity
EVS81_RS08790	COG4585	Histidine kinase
EVS81_RS08815	COG0628	permease
EVS81_RS08825	COG2015	COG2015, Alkyl sulfatase and related hydrolases
EVS81_RS08830	COG2149	membrane
EVS81_RS08880	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EVS81_RS08915	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EVS81_RS08920	COG0187	DNA topoisomerase II activity
EVS81_RS08930	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EVS81_RS08935	COG0592	DNA-directed DNA polymerase activity
EVS81_RS08940	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EVS81_RS08945	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EVS81_RS08950	COG0594	ribonuclease P activity
EVS81_RS08955	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EVS81_RS08960	COG0706	membrane insertase activity
EVS81_RS08965	COG1847	R3H domain protein
EVS81_RS08970	COG0357	Ribosomal RNA small subunit methyltransferase G
EVS81_RS08975	COG1192	Involved in chromosome partitioning
EVS81_RS08985	COG3118	belongs to the thioredoxin family
EVS81_RS08990	COG0492	ferredoxin-NADP+ reductase activity
EVS81_RS09000	COG0617	tRNA 3'-terminal CCA addition
EVS81_RS09005	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EVS81_RS09010	COG0360	Binds together with S18 to 16S ribosomal RNA
EVS81_RS09020	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EVS81_RS09025	COG0359	binds to the 23S rRNA
EVS81_RS09030	COG0305	Participates in initiation and elongation during chromosome replication
EVS81_RS09060	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EVS81_RS09070	COG1950	PFAM Membrane protein of
EVS81_RS09075	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EVS81_RS09085	COG0022	dehydrogenase e1 component
EVS81_RS09090	COG0508	dehydrogenase complex catalyzes the overall conversion of
EVS81_RS09100	COG1174	glycine betaine transport
EVS81_RS09110	COG1174	glycine betaine transport
EVS81_RS09125	COG2084	Dehydrogenase
EVS81_RS09135	COG1028	Short-chain dehydrogenase reductase Sdr
EVS81_RS09140	COG0277	FAD linked oxidase domain protein
EVS81_RS09145	COG1070	Carbohydrate kinase
EVS81_RS09150	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EVS81_RS09175	COG0438	transferase activity, transferring glycosyl groups
EVS81_RS09185	COG2188	Transcriptional regulator
EVS81_RS09190	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EVS81_RS09205	COG3718	enzyme involved in inositol metabolism
EVS81_RS09210	COG3962	Belongs to the TPP enzyme family
EVS81_RS09225	COG1082	Xylose isomerase domain protein TIM barrel
EVS81_RS09235	COG2814	Major facilitator Superfamily
EVS81_RS09260	COG0673	inositol 2-dehydrogenase activity
EVS81_RS09270	COG1609	Transcriptional regulator
EVS81_RS09280	COG3962	Belongs to the TPP enzyme family
EVS81_RS09290	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EVS81_RS09300	COG1846	Transcriptional regulator
EVS81_RS09320	COG1028	Short-chain dehydrogenase reductase Sdr
EVS81_RS09325	COG0673	inositol 2-dehydrogenase activity
EVS81_RS09345	COG1260	myo-inositol-1-phosphate synthase
EVS81_RS09350	COG0483	inositol monophosphate 1-phosphatase activity
EVS81_RS09365	COG1121	(ABC) transporter
EVS81_RS09370	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EVS81_RS09375	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EVS81_RS09410	COG1126	abc transporter atp-binding protein
EVS81_RS09415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EVS81_RS09420	COG0765	amino acid transport
EVS81_RS09425	COG0765	amino acid transport
EVS81_RS09435	COG0667	Aldo Keto reductase
EVS81_RS09445	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EVS81_RS09450	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EVS81_RS09455	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EVS81_RS09460	COG0776	regulation of translation
EVS81_RS09465	COG3336	cytochrome c oxidase
EVS81_RS09470	COG0717	Belongs to the dCTP deaminase family
EVS81_RS09475	COG0402	S-adenosylhomocysteine deaminase activity
EVS81_RS09505	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
EVS81_RS09510	COG1116	anion transmembrane transporter activity
EVS81_RS09510	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EVS81_RS09520	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EVS81_RS09530	COG1609	Transcriptional regulator
EVS81_RS09540	COG0702	epimerase
EVS81_RS09610	COG1129	ABC transporter
EVS81_RS09630	COG2084	Dehydrogenase
EVS81_RS09640	COG1396	sequence-specific DNA binding
EVS81_RS09645	COG1063	alcohol dehydrogenase
EVS81_RS09660	COG2188	Transcriptional regulator
EVS81_RS09670	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EVS81_RS09675	COG0508	dehydrogenase complex catalyzes the overall conversion of
EVS81_RS09680	COG1309	transcriptional regulator
EVS81_RS09685	COG2409	Drug exporters of the RND superfamily
EVS81_RS09715	COG1574	metal-dependent hydrolase with the TIM-barrel fold
EVS81_RS09735	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EVS81_RS09740	COG0431	NADPH-dependent FMN reductase
EVS81_RS09760	COG1028	Short-chain dehydrogenase reductase Sdr
EVS81_RS09760	COG3347	Dehydrogenase
EVS81_RS09770	COG1349	DNA-binding transcription factor activity
EVS81_RS09780	COG1172	Belongs to the binding-protein-dependent transport system permease family
EVS81_RS09785	COG1879	ABC-type sugar transport system periplasmic component
EVS81_RS09800	COG1070	Carbohydrate kinase
EVS81_RS09820	COG1879	ABC-type sugar transport system periplasmic component
EVS81_RS09825	COG1172	Belongs to the binding-protein-dependent transport system permease family
EVS81_RS09830	COG1172	Belongs to the binding-protein-dependent transport system permease family
EVS81_RS09835	COG1129	ABC transporter
EVS81_RS09840	COG1609	Transcriptional regulator
EVS81_RS09845	COG2197	response regulator
EVS81_RS09850	COG4585	Histidine kinase
EVS81_RS09855	COG4152	abc transporter atp-binding protein
EVS81_RS09870	COG1309	transcriptional regulator
EVS81_RS09875	COG2190	(PTS) system
EVS81_RS09875	COG2211	Major facilitator Superfamily
EVS81_RS09885	COG0011	TIGRFAM Protein of
EVS81_RS09940	COG2244	polysaccharide biosynthetic process
EVS81_RS09950	COG0489	protein tyrosine kinase activity
EVS81_RS10020	COG1132	(ABC) transporter
EVS81_RS10035	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EVS81_RS10050	COG1780	Probably involved in ribonucleotide reductase function
EVS81_RS10055	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EVS81_RS10060	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EVS81_RS10070	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EVS81_RS10085	COG0477	Major facilitator Superfamily
EVS81_RS10090	COG0028	Belongs to the TPP enzyme family
EVS81_RS10100	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EVS81_RS10110	COG0183	Belongs to the thiolase family
EVS81_RS10120	COG1289	transmembrane transporter activity
EVS81_RS10125	COG1834	amidinotransferase
EVS81_RS10130	COG2902	Dehydrogenase
EVS81_RS10135	COG0542	response to heat
EVS81_RS10145	COG0667	Aldo Keto reductase
EVS81_RS10150	COG1940	carbohydrate kinase activity
EVS81_RS10155	COG0673	inositol 2-dehydrogenase activity
EVS81_RS10160	COG1129	ABC transporter
EVS81_RS10165	COG1172	Belongs to the binding-protein-dependent transport system permease family
EVS81_RS10190	COG0406	alpha-ribazole phosphatase activity
EVS81_RS10200	COG0785	Cytochrome C biogenesis protein
EVS81_RS10205	COG1333	cytochrome c biogenesis protein
EVS81_RS10230	COG0076	glutamate decarboxylase activity
EVS81_RS10240	COG4592	Periplasmic binding protein
EVS81_RS10245	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EVS81_RS10250	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EVS81_RS10255	COG1120	ATPase activity
EVS81_RS10260	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EVS81_RS10265	COG2375	cellular response to nickel ion
EVS81_RS10275	COG1028	Short-chain dehydrogenase reductase Sdr
EVS81_RS10285	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EVS81_RS10320	COG2169	Transcriptional regulator
EVS81_RS10320	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EVS81_RS10340	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EVS81_RS10350	COG0514	ATP-dependent DNA helicase (RecQ)
EVS81_RS10355	COG0443	Heat shock 70 kDa protein
EVS81_RS10360	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EVS81_RS10365	COG0484	heat shock protein binding
EVS81_RS10370	COG0789	Transcriptional regulator
EVS81_RS10375	COG2813	Specifically methylates the guanine in position
EVS81_RS10395	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EVS81_RS10400	COG2326	polyphosphate kinase activity
EVS81_RS10405	COG1169	isochorismate synthase
EVS81_RS10410	COG2226	methyltransferase
EVS81_RS10415	COG0142	geranyltranstransferase activity
EVS81_RS10440	COG0531	amino acid
EVS81_RS10450	COG0019	diaminopimelate decarboxylase activity
EVS81_RS10465	COG1126	abc transporter atp-binding protein
EVS81_RS10475	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EVS81_RS10505	COG0798	PFAM Bile acid sodium symporter
EVS81_RS10515	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EVS81_RS10520	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EVS81_RS10530	COG0659	secondary active sulfate transmembrane transporter activity
EVS81_RS10570	COG0656	L-ascorbic acid biosynthetic process
EVS81_RS10580	COG3559	Exporter of polyketide antibiotics
EVS81_RS10585	COG1131	(ABC) transporter
EVS81_RS10590	COG1309	transcriptional regulator
EVS81_RS10600	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EVS81_RS10610	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EVS81_RS10625	COG0803	Belongs to the bacterial solute-binding protein 9 family
EVS81_RS10635	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EVS81_RS10640	COG1121	(ABC) transporter
EVS81_RS10665	COG1929	Belongs to the glycerate kinase type-1 family
EVS81_RS10690	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EVS81_RS10695	COG0037	tRNA processing
EVS81_RS10695	COG0590	tRNA wobble adenosine to inosine editing
EVS81_RS10720	COG3639	organic phosphonate transmembrane transporter activity
EVS81_RS10725	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
EVS81_RS10750	COG2084	Dehydrogenase
EVS81_RS10770	COG1012	belongs to the aldehyde dehydrogenase family
EVS81_RS10775	COG0477	Major facilitator Superfamily
EVS81_RS10790	COG0569	domain protein
EVS81_RS10800	COG0640	Transcriptional regulator
EVS81_RS10845	COG4585	Histidine kinase
EVS81_RS10890	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EVS81_RS10890	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EVS81_RS10905	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EVS81_RS10915	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EVS81_RS10920	COG4948	Mandelate Racemase Muconate Lactonizing
EVS81_RS10930	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EVS81_RS10945	COG1132	(ABC) transporter
EVS81_RS10950	COG1132	(ABC) transporter
EVS81_RS10965	COG0438	transferase activity, transferring glycosyl groups
EVS81_RS10975	COG1126	abc transporter atp-binding protein
EVS81_RS10980	COG0765	amino acid transport
EVS81_RS10985	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EVS81_RS11000	COG0730	response to heat
EVS81_RS11020	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EVS81_RS11025	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EVS81_RS11025	COG1116	anion transmembrane transporter activity
EVS81_RS11050	COG0033	Phosphoglucomutase
EVS81_RS11060	COG1597	lipid kinase activity
EVS81_RS11065	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EVS81_RS11115	COG1012	belongs to the aldehyde dehydrogenase family
EVS81_RS11120	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EVS81_RS11125	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
EVS81_RS11130	COG1177	transmembrane transport
EVS81_RS11135	COG1176	ABC-type spermidine putrescine transport system, permease component I
EVS81_RS11140	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EVS81_RS11145	COG3842	ATPase activity
EVS81_RS11160	COG0662	Cupin 2, conserved barrel domain protein
EVS81_RS11160	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
EVS81_RS11165	COG2009	succinate dehydrogenase
EVS81_RS11195	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EVS81_RS11215	COG1176	ABC-type spermidine putrescine transport system, permease component I
EVS81_RS11220	COG4149	molybdate abc transporter
EVS81_RS11225	COG3842	ATPase activity
EVS81_RS11230	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EVS81_RS11275	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EVS81_RS11285	COG1063	alcohol dehydrogenase
EVS81_RS11305	COG0424	maF-like protein
EVS81_RS11320	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EVS81_RS11345	COG1511	domain protein
EVS81_RS11345	COG1511	domain protein
EVS81_RS11350	COG1309	transcriptional regulator
EVS81_RS11355	COG0436	Aminotransferase
EVS81_RS11365	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EVS81_RS11380	COG1414	Transcriptional regulator
EVS81_RS11390	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EVS81_RS11395	COG0081	regulation of translation
EVS81_RS11400	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EVS81_RS11410	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
EVS81_RS11415	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
EVS81_RS11420	COG3639	organic phosphonate transmembrane transporter activity
EVS81_RS11440	COG0714	Associated with various cellular activities
EVS81_RS11455	COG0631	protein serine/threonine phosphatase activity
EVS81_RS11465	COG1404	Belongs to the peptidase S8 family
EVS81_RS11530	COG1404	Belongs to the peptidase S8 family
EVS81_RS11540	COG1674	ftsk spoiiie
EVS81_RS11550	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EVS81_RS11585	COG2188	Transcriptional regulator
EVS81_RS11600	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
EVS81_RS11605	COG3639	organic phosphonate transmembrane transporter activity
EVS81_RS11615	COG1846	Transcriptional regulator
EVS81_RS11620	COG0477	Major facilitator Superfamily
EVS81_RS11635	COG2814	Major facilitator Superfamily
EVS81_RS11645	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EVS81_RS11650	COG1316	TRANSCRIPTIONal
EVS81_RS11655	COG1368	sulfuric ester hydrolase activity
EVS81_RS11680	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EVS81_RS11685	COG0673	inositol 2-dehydrogenase activity
EVS81_RS11720	COG1132	(ABC) transporter
EVS81_RS11745	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EVS81_RS11755	COG1216	Glycosyl transferase, family 2
EVS81_RS11775	COG1216	Glycosyl transferase, family 2
EVS81_RS11790	COG1482	cell wall glycoprotein biosynthetic process
EVS81_RS11800	COG0196	riboflavin kinase activity
EVS81_RS11805	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EVS81_RS11810	COG0205	6-phosphofructokinase activity
EVS81_RS11830	COG1012	belongs to the aldehyde dehydrogenase family
EVS81_RS11840	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EVS81_RS11845	COG1309	transcriptional regulator
EVS81_RS11850	COG1228	amidohydrolase
EVS81_RS11855	COG0531	amino acid
EVS81_RS11860	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EVS81_RS11880	COG0514	ATP-dependent DNA helicase (RecQ)
EVS81_RS11890	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EVS81_RS11900	COG0402	S-adenosylhomocysteine deaminase activity
EVS81_RS11905	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
EVS81_RS11915	COG1854	S-ribosylhomocysteine lyase activity
EVS81_RS11930	COG2354	Protein conserved in bacteria
EVS81_RS11950	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EVS81_RS11960	COG0579	oxidoreductase
EVS81_RS11975	COG1982	Orn Lys Arg decarboxylase major
EVS81_RS12015	COG0559	Belongs to the binding-protein-dependent transport system permease family
EVS81_RS12030	COG0174	glutamine synthetase
EVS81_RS12035	COG1473	amidohydrolase
EVS81_RS12040	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EVS81_RS12045	COG0165	Argininosuccinate lyase
EVS81_RS12050	COG3314	Sporulation integral membrane protein YlbJ
EVS81_RS12055	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EVS81_RS12060	COG1216	Glycosyl transferase, family 2
EVS81_RS12065	COG0653	protein targeting
EVS81_RS12100	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
EVS81_RS12105	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EVS81_RS12110	COG4558	Periplasmic binding protein
EVS81_RS12120	COG0459	protein refolding
EVS81_RS12130	COG2205	protein histidine kinase activity
EVS81_RS12135	COG0745	RESPONSE REGULATOR receiver
EVS81_RS12140	COG1061	Type III restriction enzyme res subunit
EVS81_RS12155	COG1278	Cold shock
EVS81_RS12165	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EVS81_RS12175	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EVS81_RS12200	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EVS81_RS12205	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EVS81_RS12210	COG0730	response to heat
EVS81_RS12225	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EVS81_RS12260	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EVS81_RS12275	COG2233	PERMEase
EVS81_RS12295	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EVS81_RS12300	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EVS81_RS12330	COG0577	efflux transmembrane transporter activity
EVS81_RS12330	COG1136	(ABC) transporter
EVS81_RS12360	COG1280	lysine exporter protein (LysE YggA)
EVS81_RS12365	COG1607	acyl-coa hydrolase
EVS81_RS12385	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EVS81_RS12410	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EVS81_RS12415	COG0494	nUDIX hydrolase
EVS81_RS12420	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EVS81_RS12425	COG0456	acetyltransferase
EVS81_RS12425	COG0454	-acetyltransferase
EVS81_RS12430	COG0745	RESPONSE REGULATOR receiver
EVS81_RS12445	COG0588	phosphoglycerate mutase activity
EVS81_RS12460	COG2733	membrane
EVS81_RS12465	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EVS81_RS12470	COG0513	Belongs to the DEAD box helicase family
EVS81_RS12505	COG0488	(ABC) transporter
EVS81_RS12530	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EVS81_RS12535	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EVS81_RS12540	COG1362	aminopeptidase activity
EVS81_RS12615	COG0785	Cytochrome C biogenesis protein
EVS81_RS12620	COG1333	cytochrome c biogenesis protein
EVS81_RS12640	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EVS81_RS12650	COG0739	heme binding
EVS81_RS12690	COG1230	cation diffusion facilitator family transporter
EVS81_RS12755	COG1266	CAAX protease self-immunity
EVS81_RS12760	COG2132	Multicopper oxidase
EVS81_RS12810	COG0741	lytic transglycosylase activity
EVS81_RS12810	COG1196	nuclear chromosome segregation
EVS81_RS12810	COG0739	heme binding
EVS81_RS12835	COG2252	PERMEase
EVS81_RS12855	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EVS81_RS12890	COG2184	nucleotidyltransferase activity
EVS81_RS13025	COG3328	transposase activity
EVS81_RS13075	COG1045	serine acetyltransferase
EVS81_RS13085	COG2890	protein-(glutamine-N5) methyltransferase activity
EVS81_RS13095	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EVS81_RS13105	COG0356	it plays a direct role in the translocation of protons across the membrane
EVS81_RS13110	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EVS81_RS13115	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EVS81_RS13120	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EVS81_RS13125	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EVS81_RS13130	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EVS81_RS13135	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EVS81_RS13140	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EVS81_RS13145	COG3022	response to hydroperoxide
EVS81_RS13150	COG0631	protein serine/threonine phosphatase activity
EVS81_RS13165	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EVS81_RS13170	COG0084	hydrolase, TatD family'
EVS81_RS13175	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EVS81_RS13180	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EVS81_RS13200	COG0488	(ABC) transporter
EVS81_RS13210	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EVS81_RS13235	COG0438	transferase activity, transferring glycosyl groups
EVS81_RS13250	COG2409	Drug exporters of the RND superfamily
EVS81_RS13255	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EVS81_RS13270	COG4977	sequence-specific DNA binding
EVS81_RS13270	COG1917	Cupin 2, conserved barrel domain protein
EVS81_RS13310	COG1196	nuclear chromosome segregation
EVS81_RS13310	COG0739	heme binding
EVS81_RS13310	COG0741	lytic transglycosylase activity
EVS81_RS13410	COG3119	arylsulfatase activity
EVS81_RS13415	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EVS81_RS13425	COG1028	Short-chain dehydrogenase reductase Sdr
EVS81_RS13450	COG1960	acyl-CoA dehydrogenase activity
EVS81_RS13455	COG1982	Orn Lys Arg decarboxylase major
EVS81_RS13465	COG1473	amidohydrolase
EVS81_RS13470	COG1288	antiporter activity
EVS81_RS13485	COG1309	transcriptional regulator
EVS81_RS13490	COG0154	amidase activity
EVS81_RS13505	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EVS81_RS13510	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EVS81_RS13515	COG1228	amidohydrolase
EVS81_RS13520	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EVS81_RS13555	COG1012	belongs to the aldehyde dehydrogenase family
EVS81_RS13565	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EVS81_RS13575	COG3971	2-oxopent-4-enoate hydratase activity
EVS81_RS13580	COG0747	negative chemotaxis
EVS81_RS13585	COG0601	transmembrane transport
EVS81_RS13590	COG0444	Belongs to the ABC transporter superfamily
EVS81_RS13615	COG2814	Major facilitator Superfamily
EVS81_RS13620	COG0657	acetylesterase activity
EVS81_RS13625	COG0657	acetylesterase activity
EVS81_RS13635	COG1063	alcohol dehydrogenase
EVS81_RS13640	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EVS81_RS13645	COG1028	Short-chain dehydrogenase reductase Sdr
EVS81_RS13695	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EVS81_RS13705	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EVS81_RS13710	COG1116	anion transmembrane transporter activity
EVS81_RS13775	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EVS81_RS13780	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EVS81_RS13785	COG1309	transcriptional regulator
EVS81_RS13810	COG4166	transmembrane transport
EVS81_RS13815	COG0601	transmembrane transport
EVS81_RS13820	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EVS81_RS13825	COG4172	Belongs to the ABC transporter superfamily
EVS81_RS13835	COG1228	amidohydrolase
EVS81_RS13870	COG0604	alcohol dehydrogenase
EVS81_RS13875	COG1476	TRANSCRIPTIONal
EVS81_RS13885	COG1012	belongs to the aldehyde dehydrogenase family
EVS81_RS13930	COG0513	Belongs to the DEAD box helicase family
EVS81_RS13965	COG0436	Aminotransferase
EVS81_RS13970	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
EVS81_RS13980	COG1113	amino acid transport
EVS81_RS13995	COG0686	Belongs to the AlaDH PNT family
EVS81_RS14000	COG1522	sequence-specific DNA binding
EVS81_RS14015	COG1902	pentaerythritol trinitrate reductase activity
EVS81_RS14020	COG1132	(ABC) transporter
EVS81_RS14035	COG3979	chitinase
EVS81_RS14045	COG1309	transcriptional regulator
EVS81_RS14060	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EVS81_RS14065	COG0248	Ppx GppA phosphatase
EVS81_RS14075	COG1982	Orn Lys Arg decarboxylase major
EVS81_RS14105	COG2197	response regulator
EVS81_RS14115	COG2409	Drug exporters of the RND superfamily
EVS81_RS14125	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EVS81_RS14135	COG1832	CoA-binding protein
EVS81_RS14145	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EVS81_RS14150	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EVS81_RS14160	COG1116	anion transmembrane transporter activity
EVS81_RS14175	COG2062	phosphohistidine phosphatase, SixA
EVS81_RS14215	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EVS81_RS14250	COG0028	Belongs to the TPP enzyme family
EVS81_RS14295	COG2066	Belongs to the glutaminase family
EVS81_RS14310	COG1028	Short-chain dehydrogenase reductase Sdr
EVS81_RS14320	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EVS81_RS14355	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EVS81_RS14360	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EVS81_RS14375	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EVS81_RS14380	COG4335	DNA alkylation repair
EVS81_RS14415	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EVS81_RS14440	COG0473	3-isopropylmalate dehydrogenase activity
EVS81_RS14445	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EVS81_RS14450	COG0179	Fumarylacetoacetate (FAA) hydrolase
EVS81_RS14480	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EVS81_RS14500	COG0477	Major facilitator Superfamily
EVS81_RS14505	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EVS81_RS14520	COG0343	queuine tRNA-ribosyltransferase activity
EVS81_RS14550	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EVS81_RS14550	COG2111	Na H antiporter
EVS81_RS14555	COG1006	Multisubunit Na H antiporter MnhC subunit
EVS81_RS14560	COG0651	ATP synthesis coupled electron transport
EVS81_RS14575	COG1320	monovalent cation:proton antiporter activity
EVS81_RS14590	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EVS81_RS14600	COG1716	ATPase activity
EVS81_RS14615	COG1192	Involved in chromosome partitioning
EVS81_RS14640	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
EVS81_RS14645	COG0515	serine threonine protein kinase
EVS81_RS14645	COG2815	serine threonine protein kinase
EVS81_RS14655	COG0142	geranyltranstransferase activity
EVS81_RS14665	COG2001	Belongs to the MraZ family
EVS81_RS14670	COG0275	rRNA processing
EVS81_RS14680	COG0768	penicillin binding
EVS81_RS14685	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EVS81_RS14695	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EVS81_RS14710	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EVS81_RS14715	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EVS81_RS14725	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EVS81_RS14730	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EVS81_RS14735	COG1799	cell septum assembly
EVS81_RS14750	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EVS81_RS14760	COG0587	DNA-directed DNA polymerase activity
EVS81_RS14765	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EVS81_RS14770	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EVS81_RS14775	COG0629	single-stranded DNA binding
EVS81_RS14795	COG1946	Acyl-CoA thioesterase
EVS81_RS14805	COG1758	RNA polymerase activity
EVS81_RS14810	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EVS81_RS14820	COG0133	tryptophan synthase activity
EVS81_RS14825	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EVS81_RS14845	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EVS81_RS14850	COG0140	phosphoribosyl-ATP diphosphatase activity
EVS81_RS14855	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EVS81_RS14860	COG0107	imidazoleglycerol-phosphate synthase activity
EVS81_RS14865	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EVS81_RS14885	COG0134	indole-3-glycerol-phosphate synthase activity
EVS81_RS14890	COG0133	tryptophan synthase activity
EVS81_RS14895	COG0159	tryptophan synthase activity
EVS81_RS14900	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EVS81_RS14905	COG0469	pyruvate kinase activity
EVS81_RS14910	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EVS81_RS14935	COG0539	negative regulation of cytoplasmic translation
EVS81_RS14945	COG0237	dephospho-CoA kinase activity
EVS81_RS14955	COG1530	ribonuclease E activity
EVS81_RS14960	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EVS81_RS14965	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EVS81_RS14970	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EVS81_RS14975	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EVS81_RS14980	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EVS81_RS14990	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EVS81_RS15000	COG0799	negative regulation of ribosome biogenesis
EVS81_RS15015	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EVS81_RS15015	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EVS81_RS15020	COG1028	Short-chain dehydrogenase reductase Sdr
EVS81_RS15035	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EVS81_RS15040	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EVS81_RS15045	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
EVS81_RS15050	COG0277	FAD linked oxidase domain protein
EVS81_RS15055	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EVS81_RS15065	COG2755	lipolytic protein G-D-S-L family
EVS81_RS15075	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EVS81_RS15085	COG0582	viral genome integration into host DNA
EVS81_RS15120	COG1414	Transcriptional regulator
EVS81_RS15150	COG2217	Heavy metal translocating P-type atpase
EVS81_RS15155	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EVS81_RS15160	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EVS81_RS15165	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EVS81_RS15170	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EVS81_RS15175	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EVS81_RS15180	COG0681	Belongs to the peptidase S26 family
EVS81_RS15185	COG0335	large ribosomal subunit rRNA binding
EVS81_RS15225	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EVS81_RS15235	COG2357	RelA SpoT domain protein
EVS81_RS15260	COG0582	viral genome integration into host DNA
EVS81_RS15265	COG0596	Alpha beta hydrolase
EVS81_RS15285	COG2239	Acts as a magnesium transporter
EVS81_RS15295	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EVS81_RS15300	COG0066	3-isopropylmalate dehydratase activity
EVS81_RS15305	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EVS81_RS15315	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EVS81_RS15320	COG1181	Belongs to the D-alanine--D-alanine ligase family
EVS81_RS15355	COG0742	ribosomal rna small subunit methyltransferase
EVS81_RS15375	COG4585	Histidine kinase
EVS81_RS15380	COG2197	response regulator
EVS81_RS15385	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EVS81_RS15395	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EVS81_RS15400	COG0571	ribonuclease III activity
EVS81_RS15405	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EVS81_RS15445	COG1196	nuclear chromosome segregation
EVS81_RS15470	COG1172	Belongs to the binding-protein-dependent transport system permease family
EVS81_RS15485	COG1316	TRANSCRIPTIONal
EVS81_RS15495	COG0228	four-way junction DNA binding
EVS81_RS15500	COG1837	Belongs to the UPF0109 family
EVS81_RS15505	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EVS81_RS15510	COG0336	Belongs to the RNA methyltransferase TrmD family
EVS81_RS15525	COG2353	YceI-like domain
EVS81_RS15540	COG0444	Belongs to the ABC transporter superfamily
EVS81_RS15545	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EVS81_RS15555	COG0747	negative chemotaxis
EVS81_RS15560	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EVS81_RS15570	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EVS81_RS15590	COG1609	Transcriptional regulator
EVS81_RS15615	COG0586	Pfam SNARE associated Golgi protein
EVS81_RS15620	COG1271	oxidase subunit
EVS81_RS15625	COG1294	oxidase, subunit
EVS81_RS15630	COG4988	ABC transporter
EVS81_RS15635	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EVS81_RS15655	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EVS81_RS15655	COG0512	Glutamine amidotransferase of anthranilate synthase
EVS81_RS15660	COG0495	leucyl-tRNA aminoacylation
EVS81_RS15680	COG0268	Binds directly to 16S ribosomal RNA
EVS81_RS15690	COG0481	GTPase activity
EVS81_RS15705	COG1420	regulation of RNA biosynthetic process