locus-tag	class	description
FGL72_RS00015	COG1253	flavin adenine dinucleotide binding
FGL72_RS00020	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FGL72_RS00025	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FGL72_RS00030	COG1780	Probably involved in ribonucleotide reductase function
FGL72_RS00055	COG0588	phosphoglycerate mutase activity
FGL72_RS00060	COG1278	Cold shock
FGL72_RS00075	COG0149	triose-phosphate isomerase activity
FGL72_RS00080	COG0085	RNA polymerase activity
FGL72_RS00085	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FGL72_RS00090	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
FGL72_RS00095	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FGL72_RS00105	COG0148	phosphopyruvate hydratase activity
FGL72_RS00110	COG2818	Glycosylase
FGL72_RS00120	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FGL72_RS00125	COG0248	Ppx GppA phosphatase
FGL72_RS00130	COG1609	Transcriptional regulator
FGL72_RS00150	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FGL72_RS00155	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FGL72_RS00160	COG1739	Uncharacterized protein family UPF0029
FGL72_RS00165	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
FGL72_RS00185	COG1309	transcriptional regulator
FGL72_RS00190	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FGL72_RS00205	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FGL72_RS00210	COG0081	regulation of translation
FGL72_RS00215	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FGL72_RS00220	COG0222	ribosome binding
FGL72_RS00225	COG2813	Specifically methylates the guanine in position
FGL72_RS00245	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FGL72_RS00250	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FGL72_RS00260	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FGL72_RS00265	COG3870	Protein conserved in bacteria
FGL72_RS00285	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FGL72_RS00305	COG1876	peptidase activity
FGL72_RS00310	COG1428	Deoxynucleoside kinase
FGL72_RS00315	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FGL72_RS00320	COG2309	aminopeptidase activity
FGL72_RS00330	COG0673	inositol 2-dehydrogenase activity
FGL72_RS00335	COG0513	Belongs to the DEAD box helicase family
FGL72_RS00345	COG0396	ATPase activity
FGL72_RS00350	COG0719	Fe-S assembly protein
FGL72_RS00355	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FGL72_RS00360	COG0822	iron-sulfur transferase activity
FGL72_RS00365	COG0719	Fe-S assembly protein
FGL72_RS00370	COG2151	metal-sulfur cluster biosynthetic enzyme
FGL72_RS00375	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FGL72_RS00380	COG0473	3-isopropylmalate dehydrogenase activity
FGL72_RS00385	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FGL72_RS00390	COG0066	3-isopropylmalate dehydratase activity
FGL72_RS00400	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
FGL72_RS00405	COG0745	RESPONSE REGULATOR receiver
FGL72_RS00410	COG5002	protein histidine kinase activity
FGL72_RS00415	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FGL72_RS00420	COG0738	Major facilitator superfamily
FGL72_RS00430	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FGL72_RS00435	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FGL72_RS00440	COG0626	cystathionine gamma-synthase activity
FGL72_RS00445	COG0626	cystathionine gamma-synthase activity
FGL72_RS00450	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FGL72_RS00455	COG1854	S-ribosylhomocysteine lyase activity
FGL72_RS00460	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FGL72_RS00465	COG4166	transmembrane transport
FGL72_RS00470	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FGL72_RS00475	COG0531	amino acid
FGL72_RS00480	COG3442	glutamine amidotransferase
FGL72_RS00485	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FGL72_RS00490	COG1435	thymidine kinase activity
FGL72_RS00495	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FGL72_RS00500	COG2890	protein-(glutamine-N5) methyltransferase activity
FGL72_RS00505	COG0009	L-threonylcarbamoyladenylate synthase
FGL72_RS00515	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FGL72_RS00530	COG1214	PFAM Peptidase M22, glycoprotease
FGL72_RS00545	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FGL72_RS00550	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
FGL72_RS00560	COG0561	phosphatase activity
FGL72_RS00570	COG0778	Nitroreductase
FGL72_RS00595	COG1482	cell wall glycoprotein biosynthetic process
FGL72_RS00605	COG3715	PTS system
FGL72_RS00610	COG3716	PTS system mannose fructose sorbose family IID component
FGL72_RS00625	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FGL72_RS00630	COG0459	protein refolding
FGL72_RS00645	COG2323	membrane
FGL72_RS00655	COG1609	Transcriptional regulator
FGL72_RS00670	COG0366	Alpha amylase catalytic
FGL72_RS00680	COG0193	aminoacyl-tRNA hydrolase activity
FGL72_RS00685	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FGL72_RS00690	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FGL72_RS00700	COG0037	tRNA processing
FGL72_RS00705	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
FGL72_RS00710	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FGL72_RS00715	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FGL72_RS00720	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FGL72_RS00750	COG2814	Major facilitator Superfamily
FGL72_RS00755	COG0531	amino acid
FGL72_RS00760	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FGL72_RS00770	COG0561	phosphatase activity
FGL72_RS00805	COG3623	hexulose-6-phosphate isomerase
FGL72_RS00825	COG2188	Transcriptional regulator
FGL72_RS00830	COG1263	PTS System
FGL72_RS00830	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FGL72_RS00830	COG2190	(PTS) system
FGL72_RS00835	COG1554	hydrolase, family 65, central catalytic
FGL72_RS00840	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FGL72_RS00885	COG2249	NAD(P)H dehydrogenase (quinone) activity
FGL72_RS00895	COG1546	Belongs to the CinA family
FGL72_RS00895	COG1058	Belongs to the CinA family
FGL72_RS00900	COG1028	Short-chain dehydrogenase reductase Sdr
FGL72_RS00915	COG2814	Major facilitator Superfamily
FGL72_RS00935	COG1122	ATPase activity
FGL72_RS00945	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FGL72_RS00955	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FGL72_RS00965	COG2188	Transcriptional regulator
FGL72_RS00975	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FGL72_RS01035	COG4493	Belongs to the UPF0637 family
FGL72_RS01045	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FGL72_RS01055	COG1597	lipid kinase activity
FGL72_RS01060	COG1892	Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four- carbon dicarboxylic acid source for the tricarboxylic acid cycle
FGL72_RS01070	COG5503	Protein of unknown function (DUF1447)
FGL72_RS01085	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FGL72_RS01090	COG1302	Protein conserved in bacteria
FGL72_RS01095	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FGL72_RS01100	COG0084	hydrolase, TatD family'
FGL72_RS01105	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FGL72_RS01110	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FGL72_RS01115	COG4466	Protein conserved in bacteria
FGL72_RS01125	COG1121	(ABC) transporter
FGL72_RS01130	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FGL72_RS01135	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FGL72_RS01140	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FGL72_RS01160	COG1555	photosystem II stabilization
FGL72_RS01160	COG1596	polysaccharide export
FGL72_RS01165	COG2333	competence protein COMEC
FGL72_RS01165	COG0658	competence protein
FGL72_RS01170	COG1466	dna polymerase III delta subunit
FGL72_RS01175	COG0268	Binds directly to 16S ribosomal RNA
FGL72_RS01180	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FGL72_RS01185	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FGL72_RS01190	COG0154	amidase activity
FGL72_RS01195	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FGL72_RS01200	COG1597	lipid kinase activity
FGL72_RS01205	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FGL72_RS01210	COG0504	CTP synthase activity
FGL72_RS01215	COG0322	excinuclease ABC activity
FGL72_RS01220	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FGL72_RS01225	COG0028	Belongs to the TPP enzyme family
FGL72_RS01230	COG1328	CTP reductase activity
FGL72_RS01235	COG0602	queuosine metabolic process
FGL72_RS01240	COG1388	LysM domain
FGL72_RS01240	COG1134	teichoic acid transport
FGL72_RS01245	COG1682	transport, permease protein
FGL72_RS01250	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FGL72_RS01265	COG1215	transferase activity, transferring glycosyl groups
FGL72_RS01270	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FGL72_RS01275	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FGL72_RS01280	COG2131	deaminase
FGL72_RS01285	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FGL72_RS01295	COG1268	BioY protein
FGL72_RS01300	COG2188	Transcriptional regulator
FGL72_RS01305	COG4175	Glycine betaine
FGL72_RS01305	COG3448	diguanylate cyclase activity
FGL72_RS01320	COG1668	transmembrane transport
FGL72_RS01325	COG4152	abc transporter atp-binding protein
FGL72_RS01395	COG3237	CsbD-like
FGL72_RS01405	COG1012	belongs to the aldehyde dehydrogenase family
FGL72_RS01410	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FGL72_RS01415	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FGL72_RS01420	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FGL72_RS01425	COG4807	Protein conserved in bacteria
FGL72_RS01430	COG0105	UTP biosynthetic process
FGL72_RS01435	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FGL72_RS01440	COG0025	NhaP-type Na H and K H
FGL72_RS01445	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FGL72_RS01455	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FGL72_RS01460	COG0571	ribonuclease III activity
FGL72_RS01465	COG1196	nuclear chromosome segregation
FGL72_RS01470	COG0552	protein localization to endoplasmic reticulum
FGL72_RS01475	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
FGL72_RS01480	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FGL72_RS01490	COG0561	phosphatase activity
FGL72_RS01495	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FGL72_RS01500	COG0366	Alpha amylase catalytic
FGL72_RS01500	COG5263	repeat protein
FGL72_RS01515	COG1215	transferase activity, transferring glycosyl groups
FGL72_RS01530	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FGL72_RS01540	COG0542	response to heat
FGL72_RS01545	COG1077	Cell shape determining protein MreB Mrl
FGL72_RS01560	COG0765	amino acid transport
FGL72_RS01565	COG1126	abc transporter atp-binding protein
FGL72_RS01575	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FGL72_RS01585	COG0612	Peptidase, M16
FGL72_RS01590	COG1426	Protein conserved in bacteria
FGL72_RS01595	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FGL72_RS01600	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FGL72_RS01605	COG0745	RESPONSE REGULATOR receiver
FGL72_RS01615	COG5002	protein histidine kinase activity
FGL72_RS01625	COG0573	inorganic phosphate transmembrane transporter activity
FGL72_RS01630	COG0581	inorganic phosphate transmembrane transporter activity
FGL72_RS01635	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FGL72_RS01640	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FGL72_RS01645	COG0704	Plays a role in the regulation of phosphate uptake
FGL72_RS01650	COG1950	PFAM Membrane protein of
FGL72_RS01655	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FGL72_RS01660	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FGL72_RS01665	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FGL72_RS01670	COG0492	ferredoxin-NADP+ reductase activity
FGL72_RS01680	COG0366	Alpha amylase catalytic
FGL72_RS01685	COG0586	Pfam SNARE associated Golgi protein
FGL72_RS01690	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FGL72_RS01695	COG0335	large ribosomal subunit rRNA binding
FGL72_RS01700	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FGL72_RS01705	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FGL72_RS01710	COG0513	Belongs to the DEAD box helicase family
FGL72_RS01730	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FGL72_RS01735	COG1696	Membrane protein involved in D-alanine export
FGL72_RS01740	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FGL72_RS01745	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FGL72_RS01750	COG1719	4-vinyl reductase, 4VR
FGL72_RS01755	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FGL72_RS01760	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FGL72_RS01770	COG2255	four-way junction helicase activity
FGL72_RS01780	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FGL72_RS01785	COG0632	four-way junction helicase activity
FGL72_RS01790	COG1428	Deoxynucleoside kinase
FGL72_RS01795	COG1970	mechanosensitive ion channel activity
FGL72_RS01815	COG0228	four-way junction DNA binding
FGL72_RS01830	COG1105	Belongs to the carbohydrate kinase PfkB family
FGL72_RS01835	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FGL72_RS01835	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FGL72_RS01835	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FGL72_RS01860	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FGL72_RS01865	COG0336	Belongs to the RNA methyltransferase TrmD family
FGL72_RS01880	COG0489	protein tyrosine kinase activity
FGL72_RS01885	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FGL72_RS01890	COG0438	transferase activity, transferring glycosyl groups
FGL72_RS01895	COG0438	transferase activity, transferring glycosyl groups
FGL72_RS01905	COG1216	Glycosyl transferase, family 2
FGL72_RS01920	COG1088	dTDP-glucose 4,6-dehydratase activity
FGL72_RS01930	COG4716	Myosin-crossreactive antigen
FGL72_RS01945	COG0415	Belongs to the DNA photolyase family
FGL72_RS01955	COG1609	Transcriptional regulator
FGL72_RS01960	COG2160	L-arabinose isomerase activity
FGL72_RS01985	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FGL72_RS01990	COG1234	tRNA 3'-trailer cleavage
FGL72_RS01995	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FGL72_RS01995	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FGL72_RS02000	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FGL72_RS02015	COG2357	RelA SpoT domain protein
FGL72_RS02020	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FGL72_RS02025	COG0564	pseudouridine synthase activity
FGL72_RS02030	COG2239	Acts as a magnesium transporter
FGL72_RS02035	COG1316	TRANSCRIPTIONal
FGL72_RS02040	COG0137	argininosuccinate synthase activity
FGL72_RS02045	COG0165	Argininosuccinate lyase
FGL72_RS02055	COG0477	Major facilitator Superfamily
FGL72_RS02060	COG1293	RNA-binding protein homologous to eukaryotic snRNP
FGL72_RS02065	COG3142	Participates in the control of copper homeostasis
FGL72_RS02070	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FGL72_RS02085	COG0586	Pfam SNARE associated Golgi protein
FGL72_RS02110	COG2171	N-acyltransferase activity
FGL72_RS02115	COG1473	amidohydrolase
FGL72_RS02120	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FGL72_RS02125	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FGL72_RS02130	COG2137	regulation of response to DNA damage stimulus
FGL72_RS02140	COG3557	Belongs to the UPF0374 family
FGL72_RS02145	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
FGL72_RS02150	COG1074	ATP-dependent DNA helicase activity
FGL72_RS02155	COG0705	Rhomboid family
FGL72_RS02165	COG1940	carbohydrate kinase activity
FGL72_RS02190	COG0562	UDP-galactopyranose mutase
FGL72_RS02195	COG0463	Glycosyl transferase, family 2
FGL72_RS02200	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FGL72_RS02210	COG2252	PERMEase
FGL72_RS02215	COG1278	Cold shock
FGL72_RS02230	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FGL72_RS02235	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FGL72_RS02245	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FGL72_RS02250	COG0670	Belongs to the BI1 family
FGL72_RS02255	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FGL72_RS02255	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FGL72_RS02260	COG0789	Transcriptional regulator
FGL72_RS02265	COG0174	glutamine synthetase
FGL72_RS02270	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FGL72_RS02275	COG1942	4-Oxalocrotonate Tautomerase
FGL72_RS02280	COG1609	Transcriptional regulator
FGL72_RS02290	COG1621	beta-fructofuranosidase activity
FGL72_RS02295	COG1940	carbohydrate kinase activity
FGL72_RS02300	COG0328	RNA-DNA hybrid ribonuclease activity
FGL72_RS02310	COG0564	pseudouridine synthase activity
FGL72_RS02315	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FGL72_RS02320	COG0505	Belongs to the CarA family
FGL72_RS02325	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FGL72_RS02335	COG2814	Major facilitator Superfamily
FGL72_RS02340	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FGL72_RS02345	COG1490	D-aminoacyl-tRNA deacylase activity
FGL72_RS02355	COG0187	DNA topoisomerase II activity
FGL72_RS02365	COG1227	inorganic diphosphatase activity
FGL72_RS02370	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FGL72_RS02375	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FGL72_RS02380	COG0779	Required for maturation of 30S ribosomal subunits
FGL72_RS02385	COG0195	Participates in both transcription termination and antitermination
FGL72_RS02390	COG2740	Nucleic-acid-binding protein implicated in transcription termination
FGL72_RS02400	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FGL72_RS02405	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FGL72_RS02410	COG0436	Aminotransferase
FGL72_RS02420	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FGL72_RS02425	COG0196	riboflavin kinase activity
FGL72_RS02430	COG1420	regulation of RNA biosynthetic process
FGL72_RS02435	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FGL72_RS02440	COG0443	Heat shock 70 kDa protein
FGL72_RS02445	COG0484	heat shock protein binding
FGL72_RS02450	COG0242	peptide deformylase activity
FGL72_RS02455	COG4476	Belongs to the UPF0223 family
FGL72_RS02460	COG0483	inositol monophosphate 1-phosphatase activity
FGL72_RS02465	COG1217	gtp-binding protein TYPA
FGL72_RS02525	COG1396	sequence-specific DNA binding
FGL72_RS02555	COG0629	single-stranded DNA binding
FGL72_RS02590	COG0662	Cupin 2, conserved barrel domain protein
FGL72_RS02630	COG0740	serine-type endopeptidase activity
FGL72_RS02720	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FGL72_RS02735	COG2962	Rard protein
FGL72_RS02745	COG2706	6-phosphogluconolactonase activity
FGL72_RS02755	COG4717	serine-type aminopeptidase activity
FGL72_RS02760	COG3481	metal-dependent phosphohydrolase, HD sub domain
FGL72_RS02765	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FGL72_RS02775	COG0537	adenosine 5'-monophosphoramidase activity
FGL72_RS02780	COG1131	(ABC) transporter
FGL72_RS02790	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FGL72_RS02880	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FGL72_RS02885	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FGL72_RS02890	COG0006	proline dipeptidase activity
FGL72_RS02905	COG0737	Belongs to the 5'-nucleotidase family
FGL72_RS02910	COG4470	Protein conserved in bacteria
FGL72_RS02920	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FGL72_RS02930	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FGL72_RS02945	COG0395	ABC-type sugar transport system, permease component
FGL72_RS02955	COG0584	glycerophosphoryl diester phosphodiesterase
FGL72_RS02960	COG0285	dihydrofolate synthase activity
FGL72_RS02965	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FGL72_RS02975	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FGL72_RS02980	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FGL72_RS02995	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FGL72_RS03005	COG0018	arginyl-trna synthetase
FGL72_RS03015	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FGL72_RS03020	COG3679	Belongs to the UPF0342 family
FGL72_RS03030	COG0540	Belongs to the ATCase OTCase family
FGL72_RS03040	COG0505	Belongs to the CarA family
FGL72_RS03045	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FGL72_RS03050	COG0167	dihydroorotate dehydrogenase activity
FGL72_RS03055	COG0284	orotidine-5'-phosphate decarboxylase activity
FGL72_RS03065	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FGL72_RS03075	COG0204	Acyl-transferase
FGL72_RS03080	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FGL72_RS03085	COG2827	Endonuclease containing a URI domain
FGL72_RS03090	COG0052	Belongs to the universal ribosomal protein uS2 family
FGL72_RS03095	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FGL72_RS03100	COG0528	UMP kinase activity
FGL72_RS03105	COG0233	cytoplasmic translational termination
FGL72_RS03110	COG0752	glycyl-tRNA synthetase alpha subunit
FGL72_RS03115	COG0751	glycine-tRNA ligase activity
FGL72_RS03120	COG0673	inositol 2-dehydrogenase activity
FGL72_RS03125	COG0697	spore germination
FGL72_RS03135	COG0604	alcohol dehydrogenase
FGL72_RS03140	COG2264	protein methyltransferase activity
FGL72_RS03145	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FGL72_RS03155	COG0488	(ABC) transporter
FGL72_RS03160	COG3425	synthase
FGL72_RS03165	COG3830	Belongs to the UPF0237 family
FGL72_RS03170	COG2848	UPF0210 protein
FGL72_RS03200	COG0302	gtp cyclohydrolase
FGL72_RS03200	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FGL72_RS03205	COG0302	gtp cyclohydrolase
FGL72_RS03210	COG0285	dihydrofolate synthase activity
FGL72_RS03225	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FGL72_RS03225	COG2190	(PTS) system
FGL72_RS03225	COG1263	PTS System
FGL72_RS03230	COG2723	6-phospho-beta-galactosidase activity
FGL72_RS03240	COG2183	response to ionizing radiation
FGL72_RS03250	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FGL72_RS03260	COG0351	phosphomethylpyrimidine kinase
FGL72_RS03265	COG4720	Psort location CytoplasmicMembrane, score
FGL72_RS03270	COG1169	isochorismate synthase
FGL72_RS03275	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FGL72_RS03280	COG0596	Alpha beta hydrolase
FGL72_RS03290	COG2384	SAM-dependent methyltransferase
FGL72_RS03295	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FGL72_RS03300	COG2195	Cleaves the N-terminal amino acid of tripeptides
FGL72_RS03305	COG2755	lipolytic protein G-D-S-L family
FGL72_RS03315	COG4479	Belongs to the UPF0346 family
FGL72_RS03325	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FGL72_RS03335	COG0446	pyridine nucleotide-disulphide oxidoreductase
FGL72_RS03350	COG2723	6-phospho-beta-galactosidase activity
FGL72_RS03365	COG3866	Pectate lyase
FGL72_RS03370	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FGL72_RS03375	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FGL72_RS03380	COG0277	FAD linked oxidase domain protein
FGL72_RS03390	COG1959	2 iron, 2 sulfur cluster binding
FGL72_RS03400	COG0577	efflux transmembrane transporter activity
FGL72_RS03415	COG1132	(ABC) transporter
FGL72_RS03425	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FGL72_RS03440	COG0463	Glycosyl transferase, family 2
FGL72_RS03460	COG0393	Putative heavy-metal-binding
FGL72_RS03475	COG1611	Belongs to the LOG family
FGL72_RS03485	COG2826	transposase and inactivated derivatives, IS30 family
FGL72_RS03525	COG1674	ftsk spoiiie
FGL72_RS03550	COG0433	COG0433 Predicted ATPase
FGL72_RS03635	COG2826	transposase and inactivated derivatives, IS30 family
FGL72_RS03710	COG1192	Involved in chromosome partitioning
FGL72_RS03735	COG0542	response to heat
FGL72_RS03925	COG0519	Catalyzes the synthesis of GMP from XMP
FGL72_RS03945	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FGL72_RS03960	COG0477	Major facilitator Superfamily
FGL72_RS04005	COG0477	Major facilitator Superfamily
FGL72_RS04010	COG1609	Transcriptional regulator
FGL72_RS04015	COG2017	converts alpha-aldose to the beta-anomer
FGL72_RS04020	COG3250	beta-galactosidase activity
FGL72_RS04035	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FGL72_RS04060	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FGL72_RS04075	COG3853	Toxic anion resistance protein (TelA)
FGL72_RS04085	COG1011	Hydrolase
FGL72_RS04090	COG0446	pyridine nucleotide-disulphide oxidoreductase
FGL72_RS04105	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FGL72_RS04115	COG2723	6-phospho-beta-galactosidase activity
FGL72_RS04120	COG2188	Transcriptional regulator
FGL72_RS04125	COG1970	mechanosensitive ion channel activity
FGL72_RS04130	COG2261	transglycosylase associated protein
FGL72_RS04140	COG1562	ergosterol biosynthetic process
FGL72_RS04145	COG1233	COG1233 Phytoene dehydrogenase and related
FGL72_RS04155	COG1028	Short-chain dehydrogenase reductase Sdr
FGL72_RS04165	COG2270	Major facilitator Superfamily
FGL72_RS04195	COG1619	proteins homologs of microcin C7 resistance protein MccF
FGL72_RS04225	COG2261	transglycosylase associated protein
FGL72_RS04230	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FGL72_RS04240	COG1053	succinate dehydrogenase
FGL72_RS04240	COG0431	NADPH-dependent FMN reductase
FGL72_RS04240	COG3976	FMN-binding domain protein
FGL72_RS04260	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FGL72_RS04265	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FGL72_RS04265	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FGL72_RS04270	COG0307	riboflavin synthase, alpha
FGL72_RS04280	COG0628	permease
FGL72_RS04285	COG1316	TRANSCRIPTIONal
FGL72_RS04290	COG3158	transport of potassium into the cell
FGL72_RS04295	COG2706	6-phosphogluconolactonase activity
FGL72_RS04300	COG0386	Belongs to the glutathione peroxidase family
FGL72_RS04305	COG1063	alcohol dehydrogenase
FGL72_RS04345	COG1573	uracil-dna glycosylase
FGL72_RS04350	COG1028	Short-chain dehydrogenase reductase Sdr
FGL72_RS04360	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FGL72_RS04365	COG0358	DNA primase activity
FGL72_RS04370	COG2826	transposase and inactivated derivatives, IS30 family
FGL72_RS04485	COG0542	response to heat
FGL72_RS04545	COG0693	protein deglycase activity
FGL72_RS04550	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FGL72_RS04585	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FGL72_RS04605	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FGL72_RS04610	COG2017	converts alpha-aldose to the beta-anomer
FGL72_RS04715	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FGL72_RS04720	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FGL72_RS04730	COG3716	PTS system mannose fructose sorbose family IID component
FGL72_RS04750	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FGL72_RS04755	COG0758	DNA mediated transformation
FGL72_RS04760	COG0488	(ABC) transporter
FGL72_RS04765	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FGL72_RS04770	COG0860	N-Acetylmuramoyl-L-alanine amidase
FGL72_RS04780	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FGL72_RS04785	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FGL72_RS04790	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FGL72_RS04795	COG0460	homoserine dehydrogenase
FGL72_RS04800	COG0083	homoserine kinase activity
FGL72_RS04805	COG0527	aspartate kinase activity
FGL72_RS04810	COG0252	asparaginase activity
FGL72_RS04815	COG1381	Involved in DNA repair and RecF pathway recombination
FGL72_RS04820	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FGL72_RS04825	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FGL72_RS04830	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FGL72_RS04835	COG1702	phosphate starvation-inducible protein PhoH
FGL72_RS04840	COG0004	ammonium transporteR
FGL72_RS04850	COG0587	DNA-directed DNA polymerase activity
FGL72_RS04870	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FGL72_RS04880	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FGL72_RS04885	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FGL72_RS04890	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FGL72_RS04895	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FGL72_RS04900	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FGL72_RS04905	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FGL72_RS04920	COG1307	EDD domain protein, DegV family
FGL72_RS04925	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FGL72_RS04930	COG0617	tRNA 3'-terminal CCA addition
FGL72_RS04960	COG1160	GTP binding
FGL72_RS04965	COG0539	negative regulation of cytoplasmic translation
FGL72_RS04970	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FGL72_RS04980	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
FGL72_RS04985	COG1187	pseudouridine synthase activity
FGL72_RS04990	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FGL72_RS04995	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FGL72_RS05005	COG4974	Belongs to the 'phage' integrase family
FGL72_RS05010	COG2996	Protein conserved in bacteria
FGL72_RS05015	COG1610	YqeY-like protein
FGL72_RS05020	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FGL72_RS05025	COG0477	Major facilitator Superfamily
FGL72_RS05030	COG2508	Transcriptional regulator
FGL72_RS05035	COG1113	amino acid transport
FGL72_RS05040	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FGL72_RS05045	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FGL72_RS05050	COG0124	histidyl-tRNA synthetase
FGL72_RS05065	COG0366	Alpha amylase catalytic
FGL72_RS05070	COG1609	Transcriptional regulator
FGL72_RS05075	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FGL72_RS05090	COG1609	Transcriptional regulator
FGL72_RS05115	COG0436	Aminotransferase
FGL72_RS05120	COG0116	Belongs to the methyltransferase superfamily
FGL72_RS05135	COG0017	Asparaginyl-tRNA synthetase
FGL72_RS05140	COG0436	Aminotransferase
FGL72_RS05150	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FGL72_RS05150	COG1199	ATP-dependent helicase activity
FGL72_RS05170	COG0667	Aldo Keto reductase
FGL72_RS05180	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FGL72_RS05185	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FGL72_RS05200	COG1744	ABC transporter substrate-binding protein PnrA-like
FGL72_RS05205	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
FGL72_RS05205	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FGL72_RS05220	COG2176	DNA-directed DNA polymerase activity
FGL72_RS05225	COG0442	prolyl-tRNA aminoacylation
FGL72_RS05230	COG0750	zinc metalloprotease
FGL72_RS05235	COG4589	Belongs to the CDS family
FGL72_RS05240	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FGL72_RS05245	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FGL72_RS05250	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FGL72_RS05260	COG1674	ftsk spoiiie
FGL72_RS05275	COG0628	permease
FGL72_RS05290	COG1304	FMN binding
FGL72_RS05300	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FGL72_RS05315	COG2759	Belongs to the formate--tetrahydrofolate ligase family
FGL72_RS05320	COG0151	Belongs to the GarS family
FGL72_RS05330	COG0138	bifunctional purine biosynthesis protein purh
FGL72_RS05335	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FGL72_RS05340	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FGL72_RS05350	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FGL72_RS05355	COG0047	phosphoribosylformylglycinamidine synthase activity
FGL72_RS05360	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FGL72_RS05365	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FGL72_RS05370	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FGL72_RS05375	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FGL72_RS05380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FGL72_RS05390	COG3599	regulation of cell shape
FGL72_RS05395	COG4474	Belongs to the UPF0398 family
FGL72_RS05405	COG3331	DNA recombination
FGL72_RS05410	COG0745	RESPONSE REGULATOR receiver
FGL72_RS05420	COG1136	(ABC) transporter
FGL72_RS05425	COG0577	efflux transmembrane transporter activity
FGL72_RS05450	COG0516	GMP reductase activity
FGL72_RS05450	COG0517	IMP dehydrogenase activity
FGL72_RS05455	COG0517	IMP dehydrogenase activity
FGL72_RS05455	COG0516	GMP reductase activity
FGL72_RS05460	COG0501	Belongs to the peptidase M48B family
FGL72_RS05465	COG1704	LemA family
FGL72_RS05480	COG2244	polysaccharide biosynthetic process
FGL72_RS05485	COG0495	leucyl-tRNA aminoacylation
FGL72_RS05490	COG0671	phosphoesterase, PA-phosphatase related
FGL72_RS05500	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FGL72_RS05515	COG1126	abc transporter atp-binding protein
FGL72_RS05520	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FGL72_RS05540	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FGL72_RS05545	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FGL72_RS05560	COG1113	amino acid transport
FGL72_RS05565	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FGL72_RS05570	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FGL72_RS05580	COG0217	transcriptional regulatory protein
FGL72_RS05590	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FGL72_RS05595	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FGL72_RS05605	COG1132	(ABC) transporter
FGL72_RS05615	COG0280	phosphate acetyltransferase
FGL72_RS05620	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FGL72_RS05630	COG2040	homocysteine
FGL72_RS05635	COG0833	amino acid
FGL72_RS05655	COG0559	Belongs to the binding-protein-dependent transport system permease family
FGL72_RS05670	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FGL72_RS05675	COG1114	Component of the transport system for branched-chain amino acids
FGL72_RS05690	COG4684	Psort location CytoplasmicMembrane, score
FGL72_RS05695	COG1447	Phosphotransferase system cellobiose-specific component IIA
FGL72_RS05700	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FGL72_RS05715	COG2302	S4 RNA-binding domain
FGL72_RS05725	COG1799	cell septum assembly
FGL72_RS05740	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FGL72_RS05745	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FGL72_RS05750	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FGL72_RS05755	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FGL72_RS05760	COG0768	penicillin binding
FGL72_RS05770	COG0275	rRNA processing
FGL72_RS05775	COG2001	Belongs to the MraZ family
FGL72_RS05790	COG1461	Dihydroxyacetone kinase
FGL72_RS05800	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FGL72_RS05805	COG3118	belongs to the thioredoxin family
FGL72_RS05815	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FGL72_RS05820	COG1162	GTPase activity
FGL72_RS05825	COG0515	serine threonine protein kinase
FGL72_RS05825	COG2815	serine threonine protein kinase
FGL72_RS05830	COG0631	protein serine/threonine phosphatase activity
FGL72_RS05835	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FGL72_RS05835	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FGL72_RS05840	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FGL72_RS05845	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FGL72_RS05850	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FGL72_RS05855	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FGL72_RS05860	COG0544	peptidyl-prolyl cis-trans isomerase activity
FGL72_RS05885	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FGL72_RS05890	COG0708	Exodeoxyribonuclease III
FGL72_RS05900	COG0456	acetyltransferase
FGL72_RS05900	COG1214	PFAM Peptidase M22, glycoprotease
FGL72_RS05905	COG0802	atpase or kinase
FGL72_RS05910	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FGL72_RS05915	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FGL72_RS05925	COG3480	Lon protease (S16) C-terminal proteolytic domain
FGL72_RS05930	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FGL72_RS05935	COG0742	ribosomal rna small subunit methyltransferase
FGL72_RS05940	COG4471	UPF0298 protein
FGL72_RS05945	COG0772	Belongs to the SEDS family
FGL72_RS05950	COG1363	Peptidase, m42
FGL72_RS05955	COG0588	phosphoglycerate mutase activity
FGL72_RS05960	COG2252	PERMEase
FGL72_RS05965	COG0497	DNA recombination
FGL72_RS05970	COG1438	arginine binding
FGL72_RS05975	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FGL72_RS05980	COG0142	geranyltranstransferase activity
FGL72_RS05985	COG1722	exodeoxyribonuclease VII activity
FGL72_RS05990	COG1570	exodeoxyribonuclease VII activity
FGL72_RS06000	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FGL72_RS06010	COG1705	Flagellar rod assembly protein muramidase FlgJ
FGL72_RS06015	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FGL72_RS06020	COG4988	ABC transporter
FGL72_RS06025	COG1294	oxidase, subunit
FGL72_RS06030	COG1271	oxidase subunit
FGL72_RS06035	COG3906	Belongs to the UPF0473 family
FGL72_RS06040	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FGL72_RS06045	COG4472	Bacterial protein of unknown function (DUF965)
FGL72_RS06050	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FGL72_RS06060	COG0531	amino acid
FGL72_RS06070	COG1070	Carbohydrate kinase
FGL72_RS06075	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FGL72_RS06080	COG1737	Transcriptional regulator
FGL72_RS06085	COG0572	uridine kinase
FGL72_RS06090	COG3527	Alpha-acetolactate decarboxylase
FGL72_RS06100	COG1609	Transcriptional regulator
FGL72_RS06120	COG0561	phosphatase activity
FGL72_RS06145	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FGL72_RS06150	COG0416	fatty acid biosynthetic process
FGL72_RS06155	COG1113	amino acid transport
FGL72_RS06165	COG3343	RNA polymerase activity
FGL72_RS06175	COG1078	dGTPase activity
FGL72_RS06185	COG2814	Major facilitator Superfamily
FGL72_RS06190	COG0308	aminopeptidase N
FGL72_RS06200	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FGL72_RS06205	COG0584	glycerophosphoryl diester phosphodiesterase
FGL72_RS06220	COG0477	Major facilitator Superfamily
FGL72_RS06225	COG1028	Short-chain dehydrogenase reductase Sdr
FGL72_RS06235	COG1309	transcriptional regulator
FGL72_RS06275	COG0095	Lipoate-protein ligase
FGL72_RS06280	COG0425	Belongs to the sulfur carrier protein TusA family
FGL72_RS06280	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FGL72_RS06285	COG4862	establishment of competence for transformation
FGL72_RS06290	COG1393	Belongs to the ArsC family
FGL72_RS06320	COG1098	S1 RNA binding domain
FGL72_RS06330	COG1758	RNA polymerase activity
FGL72_RS06335	COG0194	GDP metabolic process
FGL72_RS06365	COG1418	mRNA catabolic process
FGL72_RS06370	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FGL72_RS06375	COG0557	exoribonuclease II activity
FGL72_RS06385	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FGL72_RS06390	COG0706	membrane insertase activity
FGL72_RS06395	COG1254	Belongs to the acylphosphatase family
FGL72_RS06400	COG5002	protein histidine kinase activity
FGL72_RS06405	COG0745	RESPONSE REGULATOR receiver
FGL72_RS06415	COG1323	Belongs to the UPF0348 family
FGL72_RS06420	COG2226	methyltransferase
FGL72_RS06425	COG0799	negative regulation of ribosome biogenesis
FGL72_RS06430	COG1713	HD superfamily hydrolase involved in NAD metabolism
FGL72_RS06435	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FGL72_RS06440	COG1534	Rna-binding protein
FGL72_RS06445	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FGL72_RS06470	COG0740	serine-type endopeptidase activity
FGL72_RS06475	COG1481	regulation of sporulation
FGL72_RS06480	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FGL72_RS06485	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FGL72_RS06490	COG0556	nucleotide-excision repair
FGL72_RS06495	COG1368	sulfuric ester hydrolase activity
FGL72_RS06515	COG0438	transferase activity, transferring glycosyl groups
FGL72_RS06520	COG1132	(ABC) transporter
FGL72_RS06525	COG1132	(ABC) transporter
FGL72_RS06530	COG1136	(ABC) transporter
FGL72_RS06530	COG0577	efflux transmembrane transporter activity
FGL72_RS06545	COG0392	lysyltransferase activity
FGL72_RS06545	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FGL72_RS06555	COG1862	Preprotein translocase
FGL72_RS06560	COG0343	queuine tRNA-ribosyltransferase activity
FGL72_RS06565	COG2003	Belongs to the UPF0758 family
FGL72_RS06570	COG2814	Major facilitator Superfamily
FGL72_RS06585	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FGL72_RS06590	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FGL72_RS06595	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FGL72_RS06600	COG0254	rRNA binding
FGL72_RS06605	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FGL72_RS06610	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FGL72_RS06610	COG0072	phenylalanine-tRNA ligase activity
FGL72_RS06615	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FGL72_RS06620	COG1733	regulation of RNA biosynthetic process
FGL72_RS06625	COG1940	carbohydrate kinase activity
FGL72_RS06645	COG1063	alcohol dehydrogenase
FGL72_RS06650	COG1609	Transcriptional regulator
FGL72_RS06675	COG0765	amino acid transport
FGL72_RS06680	COG1126	abc transporter atp-binding protein
FGL72_RS06685	COG0765	amino acid transport
FGL72_RS06690	COG1744	ABC transporter substrate-binding protein PnrA-like
FGL72_RS06725	COG1484	DNA-dependent DNA replication
FGL72_RS06745	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FGL72_RS06750	COG1193	negative regulation of DNA recombination
FGL72_RS06765	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FGL72_RS06780	COG2272	Belongs to the type-B carboxylesterase lipase family
FGL72_RS06795	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
FGL72_RS06810	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FGL72_RS06825	COG3620	sequence-specific DNA binding
FGL72_RS06850	COG2226	methyltransferase
FGL72_RS06875	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FGL72_RS06880	COG0439	Biotin carboxylase
FGL72_RS06890	COG0511	ligase activity, forming carbon-carbon bonds
FGL72_RS06895	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FGL72_RS06905	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FGL72_RS06915	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FGL72_RS06920	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FGL72_RS06930	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FGL72_RS06945	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FGL72_RS06945	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FGL72_RS06950	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FGL72_RS06950	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FGL72_RS06955	COG1418	mRNA catabolic process
FGL72_RS06960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FGL72_RS06965	COG0765	amino acid transport
FGL72_RS06970	COG1126	abc transporter atp-binding protein
FGL72_RS06980	COG0492	ferredoxin-NADP+ reductase activity
FGL72_RS06990	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FGL72_RS06995	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FGL72_RS07015	COG0352	thiamine-phosphate diphosphorylase activity
FGL72_RS07020	COG0351	phosphomethylpyrimidine kinase
FGL72_RS07025	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FGL72_RS07060	COG0768	penicillin binding
FGL72_RS07070	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FGL72_RS07075	COG4975	Glucose uptake
FGL72_RS07085	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FGL72_RS07115	COG4537	Required for transformation and DNA binding
FGL72_RS07120	COG1459	type II secretion system
FGL72_RS07125	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FGL72_RS07130	COG0166	Belongs to the GPI family
FGL72_RS07135	COG0363	glucosamine-6-phosphate deaminase activity
FGL72_RS07150	COG0745	RESPONSE REGULATOR receiver
FGL72_RS07160	COG0012	GTP binding
FGL72_RS07165	COG4481	Protein conserved in bacteria
FGL72_RS07170	COG1475	DNA binding
FGL72_RS07175	COG1192	Involved in chromosome partitioning
FGL72_RS07180	COG0357	Ribosomal RNA small subunit methyltransferase G
FGL72_RS07210	COG0640	Transcriptional regulator
FGL72_RS07225	COG1914	H( )-stimulated, divalent metal cation uptake system
FGL72_RS07235	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FGL72_RS07260	COG1316	TRANSCRIPTIONal
FGL72_RS07270	COG1388	LysM domain
FGL72_RS07270	COG3584	3D domain protein
FGL72_RS07280	COG3942	CHAP domain
FGL72_RS07280	COG1388	LysM domain
FGL72_RS07285	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FGL72_RS07295	COG0525	valine-tRNA ligase activity
FGL72_RS07305	COG2337	Toxic component of a toxin-antitoxin (TA) module
FGL72_RS07310	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FGL72_RS07315	COG0736	holo-[acyl-carrier-protein] synthase activity
FGL72_RS07375	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FGL72_RS07380	COG0436	Aminotransferase
FGL72_RS07385	COG0194	GDP metabolic process
FGL72_RS07390	COG0531	amino acid
FGL72_RS07395	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
FGL72_RS07400	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FGL72_RS07410	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FGL72_RS07420	COG0589	response to stress
FGL72_RS07430	COG1181	Belongs to the D-alanine--D-alanine ligase family
FGL72_RS07440	COG0772	Belongs to the SEDS family
FGL72_RS07450	COG1077	Cell shape determining protein MreB Mrl
FGL72_RS07460	COG0833	amino acid
FGL72_RS07470	COG0730	response to heat
FGL72_RS07480	COG1316	TRANSCRIPTIONal
FGL72_RS07485	COG0180	Tryptophanyl-tRNA synthetase
FGL72_RS07490	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FGL72_RS07515	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FGL72_RS07535	COG0628	permease
FGL72_RS07540	COG1194	a g-specific adenine glycosylase
FGL72_RS07545	COG2814	Major facilitator Superfamily
FGL72_RS07550	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FGL72_RS07555	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FGL72_RS07570	COG5002	protein histidine kinase activity
FGL72_RS07575	COG0745	RESPONSE REGULATOR receiver
FGL72_RS07580	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FGL72_RS07585	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FGL72_RS07590	COG0561	phosphatase activity
FGL72_RS07600	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FGL72_RS07610	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FGL72_RS07615	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
FGL72_RS07620	COG2188	Transcriptional regulator
FGL72_RS07625	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FGL72_RS07630	COG0305	Participates in initiation and elongation during chromosome replication
FGL72_RS07635	COG0359	binds to the 23S rRNA
FGL72_RS07645	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FGL72_RS07650	COG0629	single-stranded DNA binding
FGL72_RS07655	COG0360	Binds together with S18 to 16S ribosomal RNA
FGL72_RS07665	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FGL72_RS07675	COG1122	ATPase activity
FGL72_RS07680	COG4720	Psort location CytoplasmicMembrane, score
FGL72_RS07690	COG1064	alcohol dehydrogenase
FGL72_RS07695	COG2130	NADP-dependent
FGL72_RS07700	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FGL72_RS07710	COG0756	dUTP diphosphatase activity
FGL72_RS07720	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FGL72_RS07725	COG1027	Aspartate ammonia-lyase
FGL72_RS07745	COG3590	peptidase
FGL72_RS07750	COG4608	Belongs to the ABC transporter superfamily
FGL72_RS07755	COG0444	Belongs to the ABC transporter superfamily
FGL72_RS07760	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FGL72_RS07765	COG0601	transmembrane transport
FGL72_RS07770	COG4166	transmembrane transport
FGL72_RS07775	COG0765	amino acid transport
FGL72_RS07780	COG0765	amino acid transport
FGL72_RS07785	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FGL72_RS07790	COG1126	abc transporter atp-binding protein
FGL72_RS07800	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FGL72_RS07805	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FGL72_RS07815	COG0488	(ABC) transporter
FGL72_RS07840	COG2199	diguanylate cyclase activity
FGL72_RS07845	COG5263	repeat protein
FGL72_RS07845	COG0366	Alpha amylase catalytic
FGL72_RS07850	COG3759	membrane
FGL72_RS07875	COG3711	transcriptional antiterminator
FGL72_RS07880	COG2723	6-phospho-beta-galactosidase activity
FGL72_RS07900	COG2207	Transcriptional regulator
FGL72_RS07905	COG1959	2 iron, 2 sulfur cluster binding
FGL72_RS07910	COG1511	domain protein
FGL72_RS07930	COG1454	alcohol dehydrogenase
FGL72_RS07930	COG1012	belongs to the aldehyde dehydrogenase family
FGL72_RS07945	COG2267	carboxylic ester hydrolase activity
FGL72_RS07965	COG3052	prosthetic group binding
FGL72_RS08000	COG4720	Psort location CytoplasmicMembrane, score
FGL72_RS08010	COG0477	Major facilitator Superfamily
FGL72_RS08035	COG4974	Belongs to the 'phage' integrase family
FGL72_RS08105	COG3759	membrane
FGL72_RS08125	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FGL72_RS08145	COG0514	ATP-dependent DNA helicase (RecQ)
FGL72_RS08150	COG0588	phosphoglycerate mutase activity
FGL72_RS08175	COG0789	Transcriptional regulator
FGL72_RS08180	COG1476	TRANSCRIPTIONal
FGL72_RS08200	COG0583	DNA-binding transcription factor activity
FGL72_RS08205	COG2855	membrane
FGL72_RS08210	COG1757	Na H antiporter
FGL72_RS08215	COG2814	Major facilitator Superfamily
FGL72_RS08255	COG0737	Belongs to the 5'-nucleotidase family
FGL72_RS08260	COG1136	(ABC) transporter
FGL72_RS08280	COG0656	L-ascorbic acid biosynthetic process
FGL72_RS08290	COG1131	(ABC) transporter
FGL72_RS08300	COG1131	(ABC) transporter
FGL72_RS08305	COG1725	Transcriptional regulator
FGL72_RS08330	COG0561	phosphatase activity
FGL72_RS08340	COG3279	Response regulator of the LytR AlgR family
FGL72_RS08355	COG2084	Dehydrogenase
FGL72_RS08360	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FGL72_RS08365	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FGL72_RS08375	COG0697	spore germination
FGL72_RS08390	COG1846	Transcriptional regulator
FGL72_RS08395	COG2814	Major facilitator Superfamily
FGL72_RS08405	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FGL72_RS08415	COG0577	efflux transmembrane transporter activity
FGL72_RS08420	COG1136	(ABC) transporter
FGL72_RS08475	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FGL72_RS08480	COG0187	DNA topoisomerase II activity
FGL72_RS08485	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FGL72_RS08495	COG0592	DNA-directed DNA polymerase activity
FGL72_RS08500	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FGL72_RS08515	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FGL72_RS08520	COG0594	ribonuclease P activity
FGL72_RS08525	COG0706	membrane insertase activity
FGL72_RS08530	COG0584	glycerophosphoryl diester phosphodiesterase
FGL72_RS08545	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FGL72_RS08550	COG0318	PFAM AMP-dependent synthetase and ligase
FGL72_RS08555	COG0183	Belongs to the thiolase family
FGL72_RS08590	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FGL72_RS08595	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FGL72_RS08600	COG0436	Aminotransferase
FGL72_RS08700	COG2814	Major facilitator Superfamily
FGL72_RS08705	COG0647	UMP catabolic process
FGL72_RS08725	COG1368	sulfuric ester hydrolase activity
FGL72_RS08730	COG0438	transferase activity, transferring glycosyl groups
FGL72_RS08740	COG0564	pseudouridine synthase activity
FGL72_RS08745	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FGL72_RS08775	COG2226	methyltransferase
FGL72_RS08785	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FGL72_RS08790	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FGL72_RS08795	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FGL72_RS08800	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FGL72_RS08805	COG1881	PFAM PEBP family protein
FGL72_RS08820	COG0477	Major facilitator Superfamily
FGL72_RS08825	COG1695	Transcriptional regulator
FGL72_RS08830	COG1764	response to oxidative stress
FGL72_RS08840	COG0569	domain protein
FGL72_RS08845	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FGL72_RS08855	COG1438	arginine binding
FGL72_RS08860	COG3845	ABC transporter
FGL72_RS08865	COG4603	Belongs to the binding-protein-dependent transport system permease family
FGL72_RS08870	COG1079	Belongs to the binding-protein-dependent transport system permease family
FGL72_RS08875	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FGL72_RS08885	COG1113	amino acid transport
FGL72_RS08890	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FGL72_RS08895	COG4120	Belongs to the binding-protein-dependent transport system permease family
FGL72_RS08925	COG0583	DNA-binding transcription factor activity
FGL72_RS08935	COG1053	succinate dehydrogenase
FGL72_RS08940	COG0471	metal ion transport
FGL72_RS08950	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FGL72_RS08955	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FGL72_RS08960	COG1307	EDD domain protein, DegV family
FGL72_RS08965	COG1272	protein, Hemolysin III
FGL72_RS08975	COG1968	undecaprenyl-diphosphatase activity
FGL72_RS08980	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FGL72_RS08990	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FGL72_RS09000	COG0356	it plays a direct role in the translocation of protons across the membrane
FGL72_RS09005	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FGL72_RS09010	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FGL72_RS09015	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FGL72_RS09020	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FGL72_RS09025	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FGL72_RS09030	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FGL72_RS09035	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FGL72_RS09045	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FGL72_RS09060	COG0737	Belongs to the 5'-nucleotidase family
FGL72_RS09065	COG1388	LysM domain
FGL72_RS09065	COG3858	chitin binding
FGL72_RS09075	COG1902	pentaerythritol trinitrate reductase activity
FGL72_RS09085	COG3973	AAA domain
FGL72_RS09090	COG1072	(Pantothenic acid kinase))
FGL72_RS09095	COG2814	Major facilitator Superfamily
FGL72_RS09115	COG0126	phosphoglycerate kinase activity
FGL72_RS09120	COG0215	cysteine-tRNA ligase activity
FGL72_RS09220	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FGL72_RS09225	COG0653	protein targeting
FGL72_RS09230	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FGL72_RS09235	COG0542	response to heat
FGL72_RS09240	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FGL72_RS09245	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FGL72_RS09250	COG0049	tRNA binding
FGL72_RS09255	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FGL72_RS09260	COG2807	transmembrane transport
FGL72_RS09265	COG3842	ATPase activity
FGL72_RS09270	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FGL72_RS09275	COG1177	transmembrane transport
FGL72_RS09285	COG0051	transcription antitermination factor activity, RNA binding
FGL72_RS09290	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FGL72_RS09295	COG0088	Forms part of the polypeptide exit tunnel
FGL72_RS09300	COG0089	rRNA binding
FGL72_RS09305	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FGL72_RS09310	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FGL72_RS09315	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FGL72_RS09320	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FGL72_RS09325	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FGL72_RS09330	COG0255	Belongs to the universal ribosomal protein uL29 family
FGL72_RS09335	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FGL72_RS09340	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FGL72_RS09345	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FGL72_RS09350	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FGL72_RS09355	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FGL72_RS09360	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FGL72_RS09365	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FGL72_RS09370	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FGL72_RS09375	COG1841	ribosomal large subunit assembly
FGL72_RS09380	COG0200	Binds to the 23S rRNA
FGL72_RS09390	COG0563	adenylate kinase activity
FGL72_RS09395	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FGL72_RS09400	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FGL72_RS09405	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FGL72_RS09410	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FGL72_RS09415	COG0202	RNA polymerase activity
FGL72_RS09420	COG0203	ribosomal protein L17
FGL72_RS09425	COG0142	geranyltranstransferase activity
FGL72_RS09435	COG1122	ATPase activity
FGL72_RS09440	COG1122	ATPase activity
FGL72_RS09450	COG0101	tRNA pseudouridine synthase activity
FGL72_RS09455	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FGL72_RS09460	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FGL72_RS09475	COG2946	Replication initiation factor
FGL72_RS09515	COG0433	COG0433 Predicted ATPase
FGL72_RS09585	COG1522	sequence-specific DNA binding
FGL72_RS09590	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FGL72_RS09595	COG3118	belongs to the thioredoxin family
FGL72_RS09600	COG0446	pyridine nucleotide-disulphide oxidoreductase
FGL72_RS09605	COG1937	Protein conserved in bacteria
FGL72_RS09615	COG0481	GTPase activity
FGL72_RS09620	COG1733	regulation of RNA biosynthetic process
FGL72_RS09625	COG2910	NAD(P)H-binding
FGL72_RS09630	COG3118	belongs to the thioredoxin family
FGL72_RS09655	COG1192	Involved in chromosome partitioning
FGL72_RS09665	COG1396	sequence-specific DNA binding