locus-tag	class	description
FGL76_RS00015	COG0640	Transcriptional regulator
FGL76_RS00045	COG0357	Ribosomal RNA small subunit methyltransferase G
FGL76_RS00050	COG1192	Involved in chromosome partitioning
FGL76_RS00055	COG1475	DNA binding
FGL76_RS00060	COG4481	Protein conserved in bacteria
FGL76_RS00065	COG0012	GTP binding
FGL76_RS00075	COG0745	RESPONSE REGULATOR receiver
FGL76_RS00090	COG0363	glucosamine-6-phosphate deaminase activity
FGL76_RS00095	COG0166	Belongs to the GPI family
FGL76_RS00100	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FGL76_RS00105	COG1459	type II secretion system
FGL76_RS00110	COG4537	Required for transformation and DNA binding
FGL76_RS00140	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FGL76_RS00150	COG4975	Glucose uptake
FGL76_RS00155	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FGL76_RS00165	COG0768	penicillin binding
FGL76_RS00200	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FGL76_RS00205	COG0351	phosphomethylpyrimidine kinase
FGL76_RS00210	COG0352	thiamine-phosphate diphosphorylase activity
FGL76_RS00230	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FGL76_RS00235	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FGL76_RS00245	COG0492	ferredoxin-NADP+ reductase activity
FGL76_RS00255	COG1126	abc transporter atp-binding protein
FGL76_RS00260	COG0765	amino acid transport
FGL76_RS00265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FGL76_RS00270	COG1418	mRNA catabolic process
FGL76_RS00275	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FGL76_RS00275	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FGL76_RS00280	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FGL76_RS00280	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FGL76_RS00295	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FGL76_RS00305	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FGL76_RS00310	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FGL76_RS00320	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FGL76_RS00330	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FGL76_RS00335	COG0511	ligase activity, forming carbon-carbon bonds
FGL76_RS00345	COG0439	Biotin carboxylase
FGL76_RS00350	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FGL76_RS00385	COG0561	phosphatase activity
FGL76_RS00395	COG3620	sequence-specific DNA binding
FGL76_RS00465	COG4974	Belongs to the 'phage' integrase family
FGL76_RS00485	COG2226	methyltransferase
FGL76_RS00500	COG0789	Transcriptional regulator
FGL76_RS00525	COG1621	beta-fructofuranosidase activity
FGL76_RS00535	COG2211	Major facilitator Superfamily
FGL76_RS00565	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
FGL76_RS00580	COG2272	Belongs to the type-B carboxylesterase lipase family
FGL76_RS00605	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FGL76_RS00620	COG1193	negative regulation of DNA recombination
FGL76_RS00625	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FGL76_RS00645	COG1484	DNA-dependent DNA replication
FGL76_RS00680	COG1744	ABC transporter substrate-binding protein PnrA-like
FGL76_RS00685	COG0765	amino acid transport
FGL76_RS00690	COG1126	abc transporter atp-binding protein
FGL76_RS00695	COG0765	amino acid transport
FGL76_RS00710	COG0295	cytidine deaminase activity
FGL76_RS00720	COG1609	Transcriptional regulator
FGL76_RS00725	COG1063	alcohol dehydrogenase
FGL76_RS00745	COG1940	carbohydrate kinase activity
FGL76_RS00750	COG1733	regulation of RNA biosynthetic process
FGL76_RS00755	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FGL76_RS00760	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FGL76_RS00760	COG0072	phenylalanine-tRNA ligase activity
FGL76_RS00765	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FGL76_RS00770	COG0254	rRNA binding
FGL76_RS00775	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FGL76_RS00780	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FGL76_RS00785	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FGL76_RS00800	COG2814	Major facilitator Superfamily
FGL76_RS00805	COG2003	Belongs to the UPF0758 family
FGL76_RS00810	COG0343	queuine tRNA-ribosyltransferase activity
FGL76_RS00815	COG1862	Preprotein translocase
FGL76_RS00825	COG0392	lysyltransferase activity
FGL76_RS00825	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FGL76_RS00840	COG1136	(ABC) transporter
FGL76_RS00840	COG0577	efflux transmembrane transporter activity
FGL76_RS00845	COG1132	(ABC) transporter
FGL76_RS00850	COG1132	(ABC) transporter
FGL76_RS00855	COG0438	transferase activity, transferring glycosyl groups
FGL76_RS00875	COG1368	sulfuric ester hydrolase activity
FGL76_RS00880	COG0556	nucleotide-excision repair
FGL76_RS00885	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FGL76_RS00890	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FGL76_RS00895	COG1481	regulation of sporulation
FGL76_RS00900	COG0740	serine-type endopeptidase activity
FGL76_RS00925	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FGL76_RS00930	COG1534	Rna-binding protein
FGL76_RS00935	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FGL76_RS00940	COG1713	HD superfamily hydrolase involved in NAD metabolism
FGL76_RS00945	COG0799	negative regulation of ribosome biogenesis
FGL76_RS00950	COG2226	methyltransferase
FGL76_RS00955	COG1323	Belongs to the UPF0348 family
FGL76_RS00965	COG0745	RESPONSE REGULATOR receiver
FGL76_RS00970	COG5002	protein histidine kinase activity
FGL76_RS00975	COG1254	Belongs to the acylphosphatase family
FGL76_RS00980	COG0706	membrane insertase activity
FGL76_RS00985	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FGL76_RS00995	COG0557	exoribonuclease II activity
FGL76_RS01000	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FGL76_RS01005	COG1418	mRNA catabolic process
FGL76_RS01035	COG0194	GDP metabolic process
FGL76_RS01040	COG1758	RNA polymerase activity
FGL76_RS01050	COG1098	S1 RNA binding domain
FGL76_RS01090	COG1393	Belongs to the ArsC family
FGL76_RS01095	COG4862	establishment of competence for transformation
FGL76_RS01100	COG0425	Belongs to the sulfur carrier protein TusA family
FGL76_RS01100	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FGL76_RS01105	COG0095	Lipoate-protein ligase
FGL76_RS01145	COG1309	transcriptional regulator
FGL76_RS01155	COG1028	Short-chain dehydrogenase reductase Sdr
FGL76_RS01160	COG0477	Major facilitator Superfamily
FGL76_RS01175	COG0584	glycerophosphoryl diester phosphodiesterase
FGL76_RS01180	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FGL76_RS01190	COG0308	aminopeptidase N
FGL76_RS01195	COG2814	Major facilitator Superfamily
FGL76_RS01205	COG1078	dGTPase activity
FGL76_RS01215	COG3343	RNA polymerase activity
FGL76_RS01225	COG1113	amino acid transport
FGL76_RS01230	COG0416	fatty acid biosynthetic process
FGL76_RS01235	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FGL76_RS01260	COG0561	phosphatase activity
FGL76_RS01280	COG1609	Transcriptional regulator
FGL76_RS01285	COG2755	lipolytic protein G-D-S-L family
FGL76_RS01285	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FGL76_RS01290	COG3527	Alpha-acetolactate decarboxylase
FGL76_RS01295	COG0572	uridine kinase
FGL76_RS01300	COG1737	Transcriptional regulator
FGL76_RS01305	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FGL76_RS01310	COG1070	Carbohydrate kinase
FGL76_RS01320	COG0531	amino acid
FGL76_RS01330	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FGL76_RS01335	COG4472	Bacterial protein of unknown function (DUF965)
FGL76_RS01340	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FGL76_RS01345	COG3906	Belongs to the UPF0473 family
FGL76_RS01350	COG1271	oxidase subunit
FGL76_RS01355	COG1294	oxidase, subunit
FGL76_RS01360	COG4988	ABC transporter
FGL76_RS01365	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FGL76_RS01370	COG1705	Flagellar rod assembly protein muramidase FlgJ
FGL76_RS01380	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FGL76_RS01390	COG1570	exodeoxyribonuclease VII activity
FGL76_RS01395	COG1722	exodeoxyribonuclease VII activity
FGL76_RS01400	COG0142	geranyltranstransferase activity
FGL76_RS01405	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FGL76_RS01410	COG1438	arginine binding
FGL76_RS01415	COG0497	DNA recombination
FGL76_RS01420	COG2252	PERMEase
FGL76_RS01425	COG0588	phosphoglycerate mutase activity
FGL76_RS01430	COG1363	Peptidase, m42
FGL76_RS01435	COG0772	Belongs to the SEDS family
FGL76_RS01440	COG4471	UPF0298 protein
FGL76_RS01445	COG0742	ribosomal rna small subunit methyltransferase
FGL76_RS01450	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FGL76_RS01455	COG3480	Lon protease (S16) C-terminal proteolytic domain
FGL76_RS01465	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FGL76_RS01470	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FGL76_RS01475	COG0802	atpase or kinase
FGL76_RS01480	COG1214	PFAM Peptidase M22, glycoprotease
FGL76_RS01480	COG0456	acetyltransferase
FGL76_RS01490	COG0708	Exodeoxyribonuclease III
FGL76_RS01495	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FGL76_RS01520	COG0544	peptidyl-prolyl cis-trans isomerase activity
FGL76_RS01525	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FGL76_RS01530	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FGL76_RS01535	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FGL76_RS01540	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FGL76_RS01545	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FGL76_RS01545	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FGL76_RS01550	COG0631	protein serine/threonine phosphatase activity
FGL76_RS01555	COG0515	serine threonine protein kinase
FGL76_RS01555	COG2815	serine threonine protein kinase
FGL76_RS01560	COG1162	GTPase activity
FGL76_RS01565	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FGL76_RS01575	COG3118	belongs to the thioredoxin family
FGL76_RS01580	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FGL76_RS01590	COG1461	Dihydroxyacetone kinase
FGL76_RS01605	COG2001	Belongs to the MraZ family
FGL76_RS01610	COG0275	rRNA processing
FGL76_RS01620	COG0768	penicillin binding
FGL76_RS01625	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FGL76_RS01630	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FGL76_RS01635	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FGL76_RS01640	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FGL76_RS01655	COG1799	cell septum assembly
FGL76_RS01665	COG2302	S4 RNA-binding domain
FGL76_RS01680	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FGL76_RS01685	COG1447	Phosphotransferase system cellobiose-specific component IIA
FGL76_RS01690	COG4684	Psort location CytoplasmicMembrane, score
FGL76_RS01705	COG1114	Component of the transport system for branched-chain amino acids
FGL76_RS01710	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FGL76_RS01725	COG0559	Belongs to the binding-protein-dependent transport system permease family
FGL76_RS01745	COG0833	amino acid
FGL76_RS01750	COG2040	homocysteine
FGL76_RS01760	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FGL76_RS01765	COG0280	phosphate acetyltransferase
FGL76_RS01775	COG1132	(ABC) transporter
FGL76_RS01785	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FGL76_RS01790	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FGL76_RS01800	COG0217	transcriptional regulatory protein
FGL76_RS01810	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FGL76_RS01815	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FGL76_RS01820	COG1113	amino acid transport
FGL76_RS01835	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FGL76_RS01840	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FGL76_RS01860	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FGL76_RS01865	COG1126	abc transporter atp-binding protein
FGL76_RS01880	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FGL76_RS01890	COG0671	phosphoesterase, PA-phosphatase related
FGL76_RS01895	COG0495	leucyl-tRNA aminoacylation
FGL76_RS01900	COG2244	polysaccharide biosynthetic process
FGL76_RS01915	COG1704	LemA family
FGL76_RS01920	COG0501	Belongs to the peptidase M48B family
FGL76_RS01925	COG0517	IMP dehydrogenase activity
FGL76_RS01925	COG0516	GMP reductase activity
FGL76_RS01930	COG0516	GMP reductase activity
FGL76_RS01930	COG0517	IMP dehydrogenase activity
FGL76_RS01955	COG0577	efflux transmembrane transporter activity
FGL76_RS01960	COG1136	(ABC) transporter
FGL76_RS01970	COG0745	RESPONSE REGULATOR receiver
FGL76_RS01975	COG3331	DNA recombination
FGL76_RS01985	COG4474	Belongs to the UPF0398 family
FGL76_RS01990	COG3599	regulation of cell shape
FGL76_RS02000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FGL76_RS02005	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FGL76_RS02010	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FGL76_RS02015	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FGL76_RS02020	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FGL76_RS02025	COG0047	phosphoribosylformylglycinamidine synthase activity
FGL76_RS02030	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FGL76_RS02045	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FGL76_RS02050	COG0138	bifunctional purine biosynthesis protein purh
FGL76_RS02060	COG0151	Belongs to the GarS family
FGL76_RS02065	COG2759	Belongs to the formate--tetrahydrofolate ligase family
FGL76_RS02080	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FGL76_RS02090	COG1304	FMN binding
FGL76_RS02105	COG0628	permease
FGL76_RS02120	COG1674	ftsk spoiiie
FGL76_RS02130	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FGL76_RS02135	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FGL76_RS02140	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FGL76_RS02145	COG4589	Belongs to the CDS family
FGL76_RS02150	COG0750	zinc metalloprotease
FGL76_RS02155	COG0442	prolyl-tRNA aminoacylation
FGL76_RS02160	COG2176	DNA-directed DNA polymerase activity
FGL76_RS02175	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
FGL76_RS02175	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FGL76_RS02180	COG1744	ABC transporter substrate-binding protein PnrA-like
FGL76_RS02195	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FGL76_RS02200	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FGL76_RS02210	COG0667	Aldo Keto reductase
FGL76_RS02230	COG1199	ATP-dependent helicase activity
FGL76_RS02230	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FGL76_RS02240	COG0436	Aminotransferase
FGL76_RS02245	COG0017	Asparaginyl-tRNA synthetase
FGL76_RS02260	COG0116	Belongs to the methyltransferase superfamily
FGL76_RS02265	COG0436	Aminotransferase
FGL76_RS02290	COG1609	Transcriptional regulator
FGL76_RS02305	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FGL76_RS02310	COG1609	Transcriptional regulator
FGL76_RS02315	COG0366	Alpha amylase catalytic
FGL76_RS02325	COG0366	Alpha amylase catalytic
FGL76_RS02330	COG0124	histidyl-tRNA synthetase
FGL76_RS02335	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FGL76_RS02340	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FGL76_RS02345	COG1113	amino acid transport
FGL76_RS02350	COG2508	Transcriptional regulator
FGL76_RS02355	COG0477	Major facilitator Superfamily
FGL76_RS02360	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FGL76_RS02365	COG1610	YqeY-like protein
FGL76_RS02370	COG2996	Protein conserved in bacteria
FGL76_RS02375	COG4974	Belongs to the 'phage' integrase family
FGL76_RS02385	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FGL76_RS02390	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FGL76_RS02395	COG1187	pseudouridine synthase activity
FGL76_RS02400	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
FGL76_RS02410	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FGL76_RS02415	COG0539	negative regulation of cytoplasmic translation
FGL76_RS02420	COG1160	GTP binding
FGL76_RS02450	COG0617	tRNA 3'-terminal CCA addition
FGL76_RS02455	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FGL76_RS02460	COG1307	EDD domain protein, DegV family
FGL76_RS02475	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FGL76_RS02480	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FGL76_RS02485	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FGL76_RS02485	COG1605	Chorismate mutase
FGL76_RS02490	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FGL76_RS02495	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FGL76_RS02500	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FGL76_RS02510	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FGL76_RS02530	COG0587	DNA-directed DNA polymerase activity
FGL76_RS02540	COG0004	ammonium transporteR
FGL76_RS02545	COG1702	phosphate starvation-inducible protein PhoH
FGL76_RS02550	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FGL76_RS02555	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FGL76_RS02560	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FGL76_RS02565	COG1381	Involved in DNA repair and RecF pathway recombination
FGL76_RS02570	COG0252	asparaginase activity
FGL76_RS02600	COG0527	aspartate kinase activity
FGL76_RS02605	COG0083	homoserine kinase activity
FGL76_RS02610	COG0460	homoserine dehydrogenase
FGL76_RS02615	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FGL76_RS02620	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FGL76_RS02625	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FGL76_RS02635	COG0860	N-Acetylmuramoyl-L-alanine amidase
FGL76_RS02640	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FGL76_RS02645	COG0488	(ABC) transporter
FGL76_RS02650	COG0758	DNA mediated transformation
FGL76_RS02655	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FGL76_RS02675	COG3716	PTS system mannose fructose sorbose family IID component
FGL76_RS02685	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FGL76_RS02690	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FGL76_RS02710	COG0358	DNA primase activity
FGL76_RS02715	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FGL76_RS02725	COG1028	Short-chain dehydrogenase reductase Sdr
FGL76_RS02730	COG1573	uracil-dna glycosylase
FGL76_RS02770	COG1063	alcohol dehydrogenase
FGL76_RS02775	COG0386	Belongs to the glutathione peroxidase family
FGL76_RS02780	COG2706	6-phosphogluconolactonase activity
FGL76_RS02785	COG3158	transport of potassium into the cell
FGL76_RS02790	COG1316	TRANSCRIPTIONal
FGL76_RS02795	COG0628	permease
FGL76_RS02805	COG0307	riboflavin synthase, alpha
FGL76_RS02810	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FGL76_RS02810	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FGL76_RS02815	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FGL76_RS02835	COG0431	NADPH-dependent FMN reductase
FGL76_RS02835	COG3976	FMN-binding domain protein
FGL76_RS02835	COG1053	succinate dehydrogenase
FGL76_RS02845	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FGL76_RS02850	COG2261	transglycosylase associated protein
FGL76_RS02880	COG1619	proteins homologs of microcin C7 resistance protein MccF
FGL76_RS02910	COG2270	Major facilitator Superfamily
FGL76_RS02920	COG1028	Short-chain dehydrogenase reductase Sdr
FGL76_RS02930	COG1233	COG1233 Phytoene dehydrogenase and related
FGL76_RS02935	COG1562	ergosterol biosynthetic process
FGL76_RS02945	COG2261	transglycosylase associated protein
FGL76_RS02950	COG1970	mechanosensitive ion channel activity
FGL76_RS02955	COG2188	Transcriptional regulator
FGL76_RS02960	COG2723	6-phospho-beta-galactosidase activity
FGL76_RS02965	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FGL76_RS02970	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FGL76_RS02985	COG0446	pyridine nucleotide-disulphide oxidoreductase
FGL76_RS02990	COG1011	Hydrolase
FGL76_RS03000	COG3853	Toxic anion resistance protein (TelA)
FGL76_RS03015	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FGL76_RS03050	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FGL76_RS03065	COG2176	DNA-directed DNA polymerase activity
FGL76_RS03070	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FGL76_RS03150	COG0433	COG0433 Predicted ATPase
FGL76_RS03165	COG1674	ftsk spoiiie
FGL76_RS03180	COG0586	Pfam SNARE associated Golgi protein
FGL76_RS03185	COG0745	RESPONSE REGULATOR receiver
FGL76_RS03195	COG0671	phosphoesterase, PA-phosphatase related
FGL76_RS03265	COG1136	(ABC) transporter
FGL76_RS03265	COG0577	efflux transmembrane transporter activity
FGL76_RS03275	COG1120	ATPase activity
FGL76_RS03405	COG0542	response to heat
FGL76_RS03500	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FGL76_RS03550	COG0463	Glycosyl transferase, family 2
FGL76_RS03620	COG2826	transposase and inactivated derivatives, IS30 family
FGL76_RS03660	COG1674	ftsk spoiiie
FGL76_RS03690	COG0433	COG0433 Predicted ATPase
FGL76_RS03710	COG3942	CHAP domain
FGL76_RS03710	COG1388	LysM domain
FGL76_RS03755	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FGL76_RS03780	COG0393	Putative heavy-metal-binding
FGL76_RS03800	COG0463	Glycosyl transferase, family 2
FGL76_RS03815	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FGL76_RS03825	COG1132	(ABC) transporter
FGL76_RS03840	COG0577	efflux transmembrane transporter activity
FGL76_RS03850	COG1959	2 iron, 2 sulfur cluster binding
FGL76_RS03860	COG0277	FAD linked oxidase domain protein
FGL76_RS03865	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FGL76_RS03870	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FGL76_RS03875	COG3866	Pectate lyase
FGL76_RS03885	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FGL76_RS03890	COG2723	6-phospho-beta-galactosidase activity
FGL76_RS03905	COG0446	pyridine nucleotide-disulphide oxidoreductase
FGL76_RS03915	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FGL76_RS03925	COG4479	Belongs to the UPF0346 family
FGL76_RS03935	COG2755	lipolytic protein G-D-S-L family
FGL76_RS03945	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FGL76_RS03950	COG2384	SAM-dependent methyltransferase
FGL76_RS03960	COG0596	Alpha beta hydrolase
FGL76_RS03965	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FGL76_RS03970	COG1169	isochorismate synthase
FGL76_RS03975	COG4720	Psort location CytoplasmicMembrane, score
FGL76_RS03980	COG0351	phosphomethylpyrimidine kinase
FGL76_RS03990	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FGL76_RS04000	COG2183	response to ionizing radiation
FGL76_RS04005	COG3711	transcriptional antiterminator
FGL76_RS04010	COG2723	6-phospho-beta-galactosidase activity
FGL76_RS04015	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FGL76_RS04015	COG1263	PTS System
FGL76_RS04015	COG2190	(PTS) system
FGL76_RS04030	COG0285	dihydrofolate synthase activity
FGL76_RS04035	COG0302	gtp cyclohydrolase
FGL76_RS04040	COG0302	gtp cyclohydrolase
FGL76_RS04040	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FGL76_RS04070	COG2848	UPF0210 protein
FGL76_RS04075	COG3830	Belongs to the UPF0237 family
FGL76_RS04080	COG3425	synthase
FGL76_RS04085	COG0488	(ABC) transporter
FGL76_RS04095	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FGL76_RS04100	COG2264	protein methyltransferase activity
FGL76_RS04105	COG0604	alcohol dehydrogenase
FGL76_RS04115	COG0697	spore germination
FGL76_RS04120	COG0673	inositol 2-dehydrogenase activity
FGL76_RS04125	COG0751	glycine-tRNA ligase activity
FGL76_RS04130	COG0752	glycyl-tRNA synthetase alpha subunit
FGL76_RS04135	COG0233	cytoplasmic translational termination
FGL76_RS04140	COG0528	UMP kinase activity
FGL76_RS04145	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FGL76_RS04150	COG0052	Belongs to the universal ribosomal protein uS2 family
FGL76_RS04155	COG2827	Endonuclease containing a URI domain
FGL76_RS04160	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FGL76_RS04165	COG0204	Acyl-transferase
FGL76_RS04175	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FGL76_RS04185	COG0284	orotidine-5'-phosphate decarboxylase activity
FGL76_RS04190	COG0167	dihydroorotate dehydrogenase activity
FGL76_RS04195	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FGL76_RS04200	COG0505	Belongs to the CarA family
FGL76_RS04210	COG0540	Belongs to the ATCase OTCase family
FGL76_RS04220	COG3679	Belongs to the UPF0342 family
FGL76_RS04225	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FGL76_RS04235	COG0018	arginyl-trna synthetase
FGL76_RS04245	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FGL76_RS04260	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FGL76_RS04265	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FGL76_RS04275	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FGL76_RS04280	COG0285	dihydrofolate synthase activity
FGL76_RS04285	COG0584	glycerophosphoryl diester phosphodiesterase
FGL76_RS04295	COG0395	ABC-type sugar transport system, permease component
FGL76_RS04300	COG1175	transmembrane transport
FGL76_RS04310	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FGL76_RS04320	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FGL76_RS04330	COG4470	Protein conserved in bacteria
FGL76_RS04335	COG0737	Belongs to the 5'-nucleotidase family
FGL76_RS04350	COG0006	proline dipeptidase activity
FGL76_RS04355	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FGL76_RS04360	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FGL76_RS04465	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FGL76_RS04475	COG1131	(ABC) transporter
FGL76_RS04480	COG0537	adenosine 5'-monophosphoramidase activity
FGL76_RS04490	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FGL76_RS04495	COG3481	metal-dependent phosphohydrolase, HD sub domain
FGL76_RS04500	COG4717	serine-type aminopeptidase activity
FGL76_RS04510	COG2706	6-phosphogluconolactonase activity
FGL76_RS04520	COG2962	Rard protein
FGL76_RS04535	COG1217	gtp-binding protein TYPA
FGL76_RS04540	COG0483	inositol monophosphate 1-phosphatase activity
FGL76_RS04545	COG4476	Belongs to the UPF0223 family
FGL76_RS04550	COG0242	peptide deformylase activity
FGL76_RS04555	COG0484	heat shock protein binding
FGL76_RS04560	COG0443	Heat shock 70 kDa protein
FGL76_RS04565	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FGL76_RS04570	COG1420	regulation of RNA biosynthetic process
FGL76_RS04575	COG0196	riboflavin kinase activity
FGL76_RS04580	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FGL76_RS04590	COG0436	Aminotransferase
FGL76_RS04595	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FGL76_RS04600	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FGL76_RS04610	COG2740	Nucleic-acid-binding protein implicated in transcription termination
FGL76_RS04615	COG0195	Participates in both transcription termination and antitermination
FGL76_RS04620	COG0779	Required for maturation of 30S ribosomal subunits
FGL76_RS04625	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FGL76_RS04630	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FGL76_RS04635	COG1227	inorganic diphosphatase activity
FGL76_RS04645	COG0187	DNA topoisomerase II activity
FGL76_RS04665	COG1490	D-aminoacyl-tRNA deacylase activity
FGL76_RS04670	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FGL76_RS04675	COG2814	Major facilitator Superfamily
FGL76_RS04685	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FGL76_RS04690	COG0505	Belongs to the CarA family
FGL76_RS04695	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FGL76_RS04700	COG0564	pseudouridine synthase activity
FGL76_RS04710	COG0328	RNA-DNA hybrid ribonuclease activity
FGL76_RS04715	COG1940	carbohydrate kinase activity
FGL76_RS04720	COG1621	beta-fructofuranosidase activity
FGL76_RS04730	COG1609	Transcriptional regulator
FGL76_RS04740	COG1942	4-Oxalocrotonate Tautomerase
FGL76_RS04745	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FGL76_RS04750	COG0174	glutamine synthetase
FGL76_RS04755	COG0789	Transcriptional regulator
FGL76_RS04760	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FGL76_RS04760	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FGL76_RS04765	COG0670	Belongs to the BI1 family
FGL76_RS04770	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FGL76_RS04780	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FGL76_RS04785	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FGL76_RS04800	COG1278	Cold shock
FGL76_RS04805	COG2252	PERMEase
FGL76_RS04815	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FGL76_RS04820	COG0463	Glycosyl transferase, family 2
FGL76_RS04825	COG0562	UDP-galactopyranose mutase
FGL76_RS04860	COG1940	carbohydrate kinase activity
FGL76_RS04870	COG0705	Rhomboid family
FGL76_RS04875	COG1074	ATP-dependent DNA helicase activity
FGL76_RS04880	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
FGL76_RS04885	COG3557	Belongs to the UPF0374 family
FGL76_RS04895	COG2137	regulation of response to DNA damage stimulus
FGL76_RS04900	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FGL76_RS04905	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FGL76_RS04910	COG1473	amidohydrolase
FGL76_RS04915	COG2171	N-acyltransferase activity
FGL76_RS04940	COG0586	Pfam SNARE associated Golgi protein
FGL76_RS04955	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FGL76_RS04960	COG3142	Participates in the control of copper homeostasis
FGL76_RS04965	COG1293	RNA-binding protein homologous to eukaryotic snRNP
FGL76_RS04970	COG0477	Major facilitator Superfamily
FGL76_RS04980	COG0165	Argininosuccinate lyase
FGL76_RS04985	COG0137	argininosuccinate synthase activity
FGL76_RS04990	COG1316	TRANSCRIPTIONal
FGL76_RS04995	COG2239	Acts as a magnesium transporter
FGL76_RS05000	COG0564	pseudouridine synthase activity
FGL76_RS05005	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FGL76_RS05010	COG2357	RelA SpoT domain protein
FGL76_RS05025	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FGL76_RS05030	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FGL76_RS05030	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FGL76_RS05035	COG1234	tRNA 3'-trailer cleavage
FGL76_RS05040	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FGL76_RS05065	COG2160	L-arabinose isomerase activity
FGL76_RS05070	COG1609	Transcriptional regulator
FGL76_RS05080	COG0415	Belongs to the DNA photolyase family
FGL76_RS05095	COG4716	Myosin-crossreactive antigen
FGL76_RS05105	COG1088	dTDP-glucose 4,6-dehydratase activity
FGL76_RS05120	COG1216	Glycosyl transferase, family 2
FGL76_RS05120	COG1442	glycosyl transferase family 8
FGL76_RS05130	COG0438	transferase activity, transferring glycosyl groups
FGL76_RS05135	COG1215	transferase activity, transferring glycosyl groups
FGL76_RS05140	COG1442	glycosyl transferase family 8
FGL76_RS05140	COG1216	Glycosyl transferase, family 2
FGL76_RS05150	COG0438	transferase activity, transferring glycosyl groups
FGL76_RS05160	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FGL76_RS05165	COG0489	protein tyrosine kinase activity
FGL76_RS05185	COG0336	Belongs to the RNA methyltransferase TrmD family
FGL76_RS05190	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FGL76_RS05210	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FGL76_RS05210	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FGL76_RS05210	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FGL76_RS05215	COG1105	Belongs to the carbohydrate kinase PfkB family
FGL76_RS05230	COG0228	four-way junction DNA binding
FGL76_RS05250	COG1970	mechanosensitive ion channel activity
FGL76_RS05255	COG1428	Deoxynucleoside kinase
FGL76_RS05260	COG0632	four-way junction helicase activity
FGL76_RS05265	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FGL76_RS05275	COG2255	four-way junction helicase activity
FGL76_RS05285	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FGL76_RS05290	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FGL76_RS05295	COG1719	4-vinyl reductase, 4VR
FGL76_RS05300	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FGL76_RS05305	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FGL76_RS05310	COG1696	Membrane protein involved in D-alanine export
FGL76_RS05315	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FGL76_RS05335	COG0513	Belongs to the DEAD box helicase family
FGL76_RS05340	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FGL76_RS05345	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FGL76_RS05350	COG0335	large ribosomal subunit rRNA binding
FGL76_RS05355	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FGL76_RS05360	COG0586	Pfam SNARE associated Golgi protein
FGL76_RS05365	COG0366	Alpha amylase catalytic
FGL76_RS05375	COG0492	ferredoxin-NADP+ reductase activity
FGL76_RS05380	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FGL76_RS05385	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FGL76_RS05390	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FGL76_RS05395	COG1950	PFAM Membrane protein of
FGL76_RS05400	COG0704	Plays a role in the regulation of phosphate uptake
FGL76_RS05405	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FGL76_RS05410	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FGL76_RS05415	COG0581	inorganic phosphate transmembrane transporter activity
FGL76_RS05420	COG0573	inorganic phosphate transmembrane transporter activity
FGL76_RS05430	COG5002	protein histidine kinase activity
FGL76_RS05440	COG0745	RESPONSE REGULATOR receiver
FGL76_RS05445	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FGL76_RS05450	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FGL76_RS05455	COG1426	Protein conserved in bacteria
FGL76_RS05460	COG0612	Peptidase, M16
FGL76_RS05470	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FGL76_RS05480	COG1126	abc transporter atp-binding protein
FGL76_RS05485	COG0765	amino acid transport
FGL76_RS05500	COG1077	Cell shape determining protein MreB Mrl
FGL76_RS05505	COG0542	response to heat
FGL76_RS05515	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FGL76_RS05530	COG1215	transferase activity, transferring glycosyl groups
FGL76_RS05545	COG5263	repeat protein
FGL76_RS05545	COG0366	Alpha amylase catalytic
FGL76_RS05550	COG5263	repeat protein
FGL76_RS05550	COG0366	Alpha amylase catalytic
FGL76_RS05555	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FGL76_RS05560	COG0561	phosphatase activity
FGL76_RS05570	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FGL76_RS05575	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
FGL76_RS05580	COG0552	protein localization to endoplasmic reticulum
FGL76_RS05585	COG1196	nuclear chromosome segregation
FGL76_RS05590	COG0571	ribonuclease III activity
FGL76_RS05595	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FGL76_RS05605	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FGL76_RS05610	COG0025	NhaP-type Na H and K H
FGL76_RS05615	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FGL76_RS05620	COG0105	UTP biosynthetic process
FGL76_RS05625	COG4807	Protein conserved in bacteria
FGL76_RS05630	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FGL76_RS05635	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FGL76_RS05640	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FGL76_RS05645	COG1012	belongs to the aldehyde dehydrogenase family
FGL76_RS05655	COG3237	CsbD-like
FGL76_RS05710	COG4152	abc transporter atp-binding protein
FGL76_RS05715	COG1668	transmembrane transport
FGL76_RS05730	COG3448	diguanylate cyclase activity
FGL76_RS05730	COG4175	Glycine betaine
FGL76_RS05735	COG2188	Transcriptional regulator
FGL76_RS05740	COG1268	BioY protein
FGL76_RS05750	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FGL76_RS05755	COG2131	deaminase
FGL76_RS05760	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FGL76_RS05765	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FGL76_RS05770	COG1215	transferase activity, transferring glycosyl groups
FGL76_RS05785	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FGL76_RS05790	COG1682	transport, permease protein
FGL76_RS05795	COG1134	teichoic acid transport
FGL76_RS05795	COG1388	LysM domain
FGL76_RS05800	COG0602	queuosine metabolic process
FGL76_RS05805	COG1328	CTP reductase activity
FGL76_RS05810	COG0028	Belongs to the TPP enzyme family
FGL76_RS05815	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FGL76_RS05820	COG0322	excinuclease ABC activity
FGL76_RS05825	COG0504	CTP synthase activity
FGL76_RS05830	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FGL76_RS05835	COG1597	lipid kinase activity
FGL76_RS05840	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FGL76_RS05845	COG0154	amidase activity
FGL76_RS05850	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FGL76_RS05855	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FGL76_RS05860	COG0268	Binds directly to 16S ribosomal RNA
FGL76_RS05865	COG1466	dna polymerase III delta subunit
FGL76_RS05870	COG0658	competence protein
FGL76_RS05870	COG2333	competence protein COMEC
FGL76_RS05895	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FGL76_RS05900	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FGL76_RS05905	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FGL76_RS05910	COG1121	(ABC) transporter
FGL76_RS05920	COG4466	Protein conserved in bacteria
FGL76_RS05925	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FGL76_RS05930	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FGL76_RS05935	COG0084	hydrolase, TatD family'
FGL76_RS05940	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FGL76_RS05945	COG1302	Protein conserved in bacteria
FGL76_RS05950	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FGL76_RS05965	COG5503	Protein of unknown function (DUF1447)
FGL76_RS05975	COG1892	Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four- carbon dicarboxylic acid source for the tricarboxylic acid cycle
FGL76_RS05980	COG1597	lipid kinase activity
FGL76_RS05990	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FGL76_RS06000	COG4493	Belongs to the UPF0637 family
FGL76_RS06060	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FGL76_RS06070	COG2188	Transcriptional regulator
FGL76_RS06080	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FGL76_RS06090	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FGL76_RS06100	COG1122	ATPase activity
FGL76_RS06115	COG5263	repeat protein
FGL76_RS06115	COG0366	Alpha amylase catalytic
FGL76_RS06120	COG2814	Major facilitator Superfamily
FGL76_RS06135	COG1028	Short-chain dehydrogenase reductase Sdr
FGL76_RS06140	COG1546	Belongs to the CinA family
FGL76_RS06140	COG1058	Belongs to the CinA family
FGL76_RS06150	COG2249	NAD(P)H dehydrogenase (quinone) activity
FGL76_RS06195	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FGL76_RS06210	COG2188	Transcriptional regulator
FGL76_RS06235	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FGL76_RS06240	COG0531	amino acid
FGL76_RS06245	COG2814	Major facilitator Superfamily
FGL76_RS06275	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FGL76_RS06280	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FGL76_RS06285	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FGL76_RS06290	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
FGL76_RS06295	COG0037	tRNA processing
FGL76_RS06305	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FGL76_RS06310	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FGL76_RS06315	COG0193	aminoacyl-tRNA hydrolase activity
FGL76_RS06325	COG0366	Alpha amylase catalytic
FGL76_RS06340	COG1609	Transcriptional regulator
FGL76_RS06350	COG2323	membrane
FGL76_RS06365	COG0459	protein refolding
FGL76_RS06370	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FGL76_RS06385	COG3716	PTS system mannose fructose sorbose family IID component
FGL76_RS06390	COG3715	PTS system
FGL76_RS06400	COG1482	cell wall glycoprotein biosynthetic process
FGL76_RS06435	COG0778	Nitroreductase
FGL76_RS06445	COG0561	phosphatase activity
FGL76_RS06455	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
FGL76_RS06460	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FGL76_RS06475	COG1214	PFAM Peptidase M22, glycoprotease
FGL76_RS06490	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FGL76_RS06500	COG0009	L-threonylcarbamoyladenylate synthase
FGL76_RS06505	COG2890	protein-(glutamine-N5) methyltransferase activity
FGL76_RS06510	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FGL76_RS06515	COG1435	thymidine kinase activity
FGL76_RS06520	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FGL76_RS06525	COG3442	glutamine amidotransferase
FGL76_RS06530	COG0531	amino acid
FGL76_RS06535	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FGL76_RS06540	COG4166	transmembrane transport
FGL76_RS06545	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FGL76_RS06550	COG1854	S-ribosylhomocysteine lyase activity
FGL76_RS06555	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FGL76_RS06560	COG0626	cystathionine gamma-synthase activity
FGL76_RS06565	COG0626	cystathionine gamma-synthase activity
FGL76_RS06570	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FGL76_RS06575	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FGL76_RS06585	COG0738	Major facilitator superfamily
FGL76_RS06590	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FGL76_RS06595	COG5002	protein histidine kinase activity
FGL76_RS06600	COG0745	RESPONSE REGULATOR receiver
FGL76_RS06605	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
FGL76_RS06615	COG0066	3-isopropylmalate dehydratase activity
FGL76_RS06620	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FGL76_RS06625	COG0473	3-isopropylmalate dehydrogenase activity
FGL76_RS06630	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FGL76_RS06635	COG2151	metal-sulfur cluster biosynthetic enzyme
FGL76_RS06640	COG0719	Fe-S assembly protein
FGL76_RS06645	COG0822	iron-sulfur transferase activity
FGL76_RS06650	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FGL76_RS06655	COG0719	Fe-S assembly protein
FGL76_RS06660	COG0396	ATPase activity
FGL76_RS06670	COG0513	Belongs to the DEAD box helicase family
FGL76_RS06675	COG0673	inositol 2-dehydrogenase activity
FGL76_RS06685	COG2309	aminopeptidase activity
FGL76_RS06690	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FGL76_RS06695	COG1428	Deoxynucleoside kinase
FGL76_RS06700	COG1876	peptidase activity
FGL76_RS06720	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FGL76_RS06740	COG3870	Protein conserved in bacteria
FGL76_RS06745	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FGL76_RS06755	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FGL76_RS06760	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FGL76_RS06780	COG2813	Specifically methylates the guanine in position
FGL76_RS06785	COG0222	ribosome binding
FGL76_RS06790	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FGL76_RS06795	COG0081	regulation of translation
FGL76_RS06800	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FGL76_RS06815	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FGL76_RS06820	COG1309	transcriptional regulator
FGL76_RS06835	COG1040	competence protein
FGL76_RS06840	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
FGL76_RS06845	COG1739	Uncharacterized protein family UPF0029
FGL76_RS06850	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FGL76_RS06855	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FGL76_RS06875	COG1609	Transcriptional regulator
FGL76_RS06880	COG0248	Ppx GppA phosphatase
FGL76_RS06885	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FGL76_RS06895	COG2818	Glycosylase
FGL76_RS06900	COG0148	phosphopyruvate hydratase activity
FGL76_RS06910	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FGL76_RS06915	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
FGL76_RS06920	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FGL76_RS06925	COG0085	RNA polymerase activity
FGL76_RS06930	COG0149	triose-phosphate isomerase activity
FGL76_RS06945	COG1278	Cold shock
FGL76_RS06950	COG0588	phosphoglycerate mutase activity
FGL76_RS06975	COG1780	Probably involved in ribonucleotide reductase function
FGL76_RS06980	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FGL76_RS06985	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FGL76_RS06990	COG1253	flavin adenine dinucleotide binding
FGL76_RS07000	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FGL76_RS07010	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FGL76_RS07015	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FGL76_RS07020	COG0101	tRNA pseudouridine synthase activity
FGL76_RS07030	COG1122	ATPase activity
FGL76_RS07035	COG1122	ATPase activity
FGL76_RS07050	COG0203	ribosomal protein L17
FGL76_RS07055	COG0202	RNA polymerase activity
FGL76_RS07060	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FGL76_RS07065	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FGL76_RS07070	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FGL76_RS07075	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FGL76_RS07080	COG0563	adenylate kinase activity
FGL76_RS07090	COG0200	Binds to the 23S rRNA
FGL76_RS07095	COG1841	ribosomal large subunit assembly
FGL76_RS07100	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FGL76_RS07105	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FGL76_RS07110	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FGL76_RS07115	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FGL76_RS07120	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FGL76_RS07125	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FGL76_RS07130	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FGL76_RS07135	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FGL76_RS07140	COG0255	Belongs to the universal ribosomal protein uL29 family
FGL76_RS07145	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FGL76_RS07150	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FGL76_RS07155	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FGL76_RS07160	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FGL76_RS07165	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FGL76_RS07170	COG0089	rRNA binding
FGL76_RS07175	COG0088	Forms part of the polypeptide exit tunnel
FGL76_RS07180	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FGL76_RS07185	COG0051	transcription antitermination factor activity, RNA binding
FGL76_RS07195	COG1177	transmembrane transport
FGL76_RS07200	COG4149	molybdate abc transporter
FGL76_RS07205	COG3842	ATPase activity
FGL76_RS07210	COG2807	transmembrane transport
FGL76_RS07215	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FGL76_RS07220	COG0049	tRNA binding
FGL76_RS07225	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FGL76_RS07230	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FGL76_RS07235	COG0542	response to heat
FGL76_RS07240	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FGL76_RS07245	COG0653	protein targeting
FGL76_RS07250	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FGL76_RS07350	COG0215	cysteine-tRNA ligase activity
FGL76_RS07355	COG0126	phosphoglycerate kinase activity
FGL76_RS07375	COG2814	Major facilitator Superfamily
FGL76_RS07385	COG3973	AAA domain
FGL76_RS07395	COG1902	pentaerythritol trinitrate reductase activity
FGL76_RS07405	COG3858	chitin binding
FGL76_RS07405	COG1388	LysM domain
FGL76_RS07410	COG0737	Belongs to the 5'-nucleotidase family
FGL76_RS07425	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FGL76_RS07435	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FGL76_RS07440	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FGL76_RS07445	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FGL76_RS07450	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FGL76_RS07455	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FGL76_RS07460	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FGL76_RS07465	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FGL76_RS07470	COG0356	it plays a direct role in the translocation of protons across the membrane
FGL76_RS07480	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FGL76_RS07490	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FGL76_RS07495	COG1968	undecaprenyl-diphosphatase activity
FGL76_RS07505	COG1272	protein, Hemolysin III
FGL76_RS07510	COG1307	EDD domain protein, DegV family
FGL76_RS07515	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FGL76_RS07520	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FGL76_RS07530	COG0471	metal ion transport
FGL76_RS07535	COG1053	succinate dehydrogenase
FGL76_RS07585	COG4120	Belongs to the binding-protein-dependent transport system permease family
FGL76_RS07590	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FGL76_RS07595	COG1113	amino acid transport
FGL76_RS07605	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FGL76_RS07610	COG1079	Belongs to the binding-protein-dependent transport system permease family
FGL76_RS07615	COG4603	Belongs to the binding-protein-dependent transport system permease family
FGL76_RS07620	COG3845	ABC transporter
FGL76_RS07625	COG1438	arginine binding
FGL76_RS07645	COG2235	arginine
FGL76_RS07660	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FGL76_RS07665	COG0569	domain protein
FGL76_RS07680	COG1695	Transcriptional regulator
FGL76_RS07685	COG0477	Major facilitator Superfamily
FGL76_RS07700	COG1881	PFAM PEBP family protein
FGL76_RS07705	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FGL76_RS07710	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FGL76_RS07715	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FGL76_RS07720	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FGL76_RS07730	COG2226	methyltransferase
FGL76_RS07745	COG2217	Heavy metal translocating P-type atpase
FGL76_RS07760	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FGL76_RS07765	COG0564	pseudouridine synthase activity
FGL76_RS07775	COG0438	transferase activity, transferring glycosyl groups
FGL76_RS07780	COG1368	sulfuric ester hydrolase activity
FGL76_RS07800	COG0647	UMP catabolic process
FGL76_RS07805	COG2814	Major facilitator Superfamily
FGL76_RS07905	COG0436	Aminotransferase
FGL76_RS07910	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FGL76_RS07915	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FGL76_RS07950	COG0183	Belongs to the thiolase family
FGL76_RS07955	COG0318	PFAM AMP-dependent synthetase and ligase
FGL76_RS07960	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FGL76_RS07975	COG0584	glycerophosphoryl diester phosphodiesterase
FGL76_RS07980	COG0706	membrane insertase activity
FGL76_RS07985	COG0594	ribonuclease P activity
FGL76_RS07990	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FGL76_RS08005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FGL76_RS08010	COG0592	DNA-directed DNA polymerase activity
FGL76_RS08020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FGL76_RS08025	COG0187	DNA topoisomerase II activity
FGL76_RS08030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FGL76_RS08080	COG0577	efflux transmembrane transporter activity
FGL76_RS08085	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FGL76_RS08095	COG2814	Major facilitator Superfamily
FGL76_RS08100	COG1846	Transcriptional regulator
FGL76_RS08105	COG1266	CAAX protease self-immunity
FGL76_RS08110	COG0488	(ABC) transporter
FGL76_RS08125	COG0697	spore germination
FGL76_RS08135	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FGL76_RS08140	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FGL76_RS08145	COG2084	Dehydrogenase
FGL76_RS08175	COG3279	Response regulator of the LytR AlgR family
FGL76_RS08185	COG0561	phosphatase activity
FGL76_RS08210	COG1725	Transcriptional regulator
FGL76_RS08215	COG1131	(ABC) transporter
FGL76_RS08225	COG1131	(ABC) transporter
FGL76_RS08235	COG0656	L-ascorbic acid biosynthetic process
FGL76_RS08255	COG1136	(ABC) transporter
FGL76_RS08260	COG0737	Belongs to the 5'-nucleotidase family
FGL76_RS08300	COG2814	Major facilitator Superfamily
FGL76_RS08305	COG1757	Na H antiporter
FGL76_RS08310	COG2855	membrane
FGL76_RS08345	COG0588	phosphoglycerate mutase activity
FGL76_RS08350	COG0514	ATP-dependent DNA helicase (RecQ)
FGL76_RS08355	COG2211	Major facilitator Superfamily
FGL76_RS08360	COG3507	Belongs to the glycosyl hydrolase 43 family
FGL76_RS08375	COG2115	Belongs to the xylose isomerase family
FGL76_RS08400	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FGL76_RS08420	COG3759	membrane
FGL76_RS08510	COG0477	Major facilitator Superfamily
FGL76_RS08520	COG4720	Psort location CytoplasmicMembrane, score
FGL76_RS08555	COG3052	prosthetic group binding
FGL76_RS08575	COG2267	carboxylic ester hydrolase activity
FGL76_RS08590	COG3842	ATPase activity
FGL76_RS08595	COG1178	ABC-type Fe3 transport system permease component
FGL76_RS08600	COG0584	glycerophosphoryl diester phosphodiesterase
FGL76_RS08605	COG1454	alcohol dehydrogenase
FGL76_RS08605	COG1012	belongs to the aldehyde dehydrogenase family
FGL76_RS08610	COG1511	domain protein
FGL76_RS08615	COG1959	2 iron, 2 sulfur cluster binding
FGL76_RS08620	COG2207	Transcriptional regulator
FGL76_RS08640	COG2723	6-phospho-beta-galactosidase activity
FGL76_RS08645	COG3711	transcriptional antiterminator
FGL76_RS08665	COG1063	alcohol dehydrogenase
FGL76_RS08670	COG3759	membrane
FGL76_RS08675	COG5263	repeat protein
FGL76_RS08675	COG0366	Alpha amylase catalytic
FGL76_RS08680	COG3706	GGDEF domain
FGL76_RS08705	COG0488	(ABC) transporter
FGL76_RS08710	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FGL76_RS08715	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FGL76_RS08720	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FGL76_RS08730	COG1126	abc transporter atp-binding protein
FGL76_RS08735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FGL76_RS08740	COG0765	amino acid transport
FGL76_RS08745	COG0765	amino acid transport
FGL76_RS08750	COG4166	transmembrane transport
FGL76_RS08755	COG0601	transmembrane transport
FGL76_RS08760	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FGL76_RS08765	COG0444	Belongs to the ABC transporter superfamily
FGL76_RS08770	COG4608	Belongs to the ABC transporter superfamily
FGL76_RS08775	COG3590	peptidase
FGL76_RS08795	COG1027	Aspartate ammonia-lyase
FGL76_RS08800	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FGL76_RS08810	COG0756	dUTP diphosphatase activity
FGL76_RS08820	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FGL76_RS08825	COG2130	NADP-dependent
FGL76_RS08830	COG1064	alcohol dehydrogenase
FGL76_RS08840	COG4720	Psort location CytoplasmicMembrane, score
FGL76_RS08845	COG1122	ATPase activity
FGL76_RS08855	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FGL76_RS08865	COG0360	Binds together with S18 to 16S ribosomal RNA
FGL76_RS08870	COG0629	single-stranded DNA binding
FGL76_RS08875	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FGL76_RS08885	COG0359	binds to the 23S rRNA
FGL76_RS08890	COG0305	Participates in initiation and elongation during chromosome replication
FGL76_RS08895	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FGL76_RS08900	COG2188	Transcriptional regulator
FGL76_RS08905	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
FGL76_RS08910	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FGL76_RS08920	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FGL76_RS08930	COG0561	phosphatase activity
FGL76_RS08935	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FGL76_RS08940	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FGL76_RS08945	COG0745	RESPONSE REGULATOR receiver
FGL76_RS08950	COG5002	protein histidine kinase activity
FGL76_RS08965	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FGL76_RS08970	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FGL76_RS08975	COG2814	Major facilitator Superfamily
FGL76_RS08980	COG1194	a g-specific adenine glycosylase
FGL76_RS08985	COG0628	permease
FGL76_RS09005	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FGL76_RS09025	COG1051	belongs to the nudix hydrolase family
FGL76_RS09030	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FGL76_RS09035	COG0180	Tryptophanyl-tRNA synthetase
FGL76_RS09040	COG1316	TRANSCRIPTIONal
FGL76_RS09050	COG0730	response to heat
FGL76_RS09060	COG0833	amino acid
FGL76_RS09070	COG1077	Cell shape determining protein MreB Mrl
FGL76_RS09080	COG0772	Belongs to the SEDS family
FGL76_RS09090	COG1181	Belongs to the D-alanine--D-alanine ligase family
FGL76_RS09100	COG0589	response to stress
FGL76_RS09110	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FGL76_RS09120	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FGL76_RS09125	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
FGL76_RS09130	COG0531	amino acid
FGL76_RS09135	COG0194	GDP metabolic process
FGL76_RS09140	COG0436	Aminotransferase
FGL76_RS09145	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FGL76_RS09205	COG0736	holo-[acyl-carrier-protein] synthase activity
FGL76_RS09210	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FGL76_RS09215	COG2337	Toxic component of a toxin-antitoxin (TA) module
FGL76_RS09225	COG0525	valine-tRNA ligase activity
FGL76_RS09235	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FGL76_RS09240	COG3942	CHAP domain
FGL76_RS09240	COG1388	LysM domain
FGL76_RS09250	COG1388	LysM domain
FGL76_RS09250	COG3584	3D domain protein
FGL76_RS09260	COG1316	TRANSCRIPTIONal
FGL76_RS09270	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FGL76_RS09270	COG0248	Ppx GppA phosphatase
FGL76_RS09285	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FGL76_RS09305	COG2271	Major facilitator Superfamily
FGL76_RS09335	COG1192	Involved in chromosome partitioning
FGL76_RS09365	COG2814	Major facilitator Superfamily
FGL76_RS09370	COG2261	transglycosylase associated protein
FGL76_RS09385	COG2801	Transposase and inactivated derivatives
FGL76_RS09390	COG1028	Short-chain dehydrogenase reductase Sdr
FGL76_RS09410	COG2261	transglycosylase associated protein
FGL76_RS09440	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FGL76_RS09450	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FGL76_RS09455	COG0297	glycogen (starch) synthase activity
FGL76_RS09460	COG0058	SHG alpha-glucan phosphorylase activity
FGL76_RS09470	COG3764	Sortase (surface protein transpeptidase)
FGL76_RS09475	COG0640	Transcriptional regulator
FGL76_RS09480	COG3118	belongs to the thioredoxin family
FGL76_RS09485	COG3118	belongs to the thioredoxin family
FGL76_RS09490	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FGL76_RS09500	COG0492	ferredoxin-NADP+ reductase activity
FGL76_RS09510	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FGL76_RS09560	COG1131	(ABC) transporter
FGL76_RS09605	COG1192	Involved in chromosome partitioning
FGL76_RS09650	COG2261	transglycosylase associated protein
FGL76_RS09665	COG1028	Short-chain dehydrogenase reductase Sdr
FGL76_RS09670	COG2801	Transposase and inactivated derivatives
FGL76_RS09680	COG2261	transglycosylase associated protein
FGL76_RS09685	COG2814	Major facilitator Superfamily
FGL76_RS09690	COG5039	Polysaccharide pyruvyl transferase
FGL76_RS09725	COG2801	Transposase and inactivated derivatives
FGL76_RS09780	COG0446	pyridine nucleotide-disulphide oxidoreductase
FGL76_RS09820	COG2217	Heavy metal translocating P-type atpase
FGL76_RS09830	COG3682	Transcriptional regulator
FGL76_RS09900	COG4619	ABC transporter
FGL76_RS09905	COG0390	transport system, permease component
FGL76_RS09930	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FGL76_RS09935	COG1192	Involved in chromosome partitioning
FGL76_RS09945	COG0662	Cupin 2, conserved barrel domain protein