locus-tag	class	description
CCX80_RS00015	COG0436	Aminotransferase
CCX80_RS00020	COG0194	GDP metabolic process
CCX80_RS00025	COG0531	amino acid
CCX80_RS00030	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
CCX80_RS00035	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CCX80_RS00045	COG2211	Major facilitator Superfamily
CCX80_RS00050	COG5506	Protein of unknown function (DUF1694)
CCX80_RS00055	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CCX80_RS00070	COG0833	amino acid
CCX80_RS00080	COG1316	TRANSCRIPTIONal
CCX80_RS00085	COG1228	amidohydrolase
CCX80_RS00090	COG4166	transmembrane transport
CCX80_RS00095	COG0531	amino acid
CCX80_RS00105	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CCX80_RS00120	COG0628	permease
CCX80_RS00125	COG1194	a g-specific adenine glycosylase
CCX80_RS00130	COG2814	Major facilitator Superfamily
CCX80_RS00135	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CCX80_RS00145	COG1902	pentaerythritol trinitrate reductase activity
CCX80_RS00150	COG1705	Flagellar rod assembly protein muramidase FlgJ
CCX80_RS00150	COG1388	LysM domain
CCX80_RS00155	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CCX80_RS00160	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CCX80_RS00165	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CCX80_RS00170	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CCX80_RS00175	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CCX80_RS00180	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CCX80_RS00185	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CCX80_RS00190	COG0356	it plays a direct role in the translocation of protons across the membrane
CCX80_RS00200	COG0588	phosphoglycerate mutase activity
CCX80_RS00205	COG1278	Cold shock
CCX80_RS00215	COG2814	Major facilitator Superfamily
CCX80_RS00225	COG3973	AAA domain
CCX80_RS00270	COG1511	domain protein
CCX80_RS00270	COG1511	domain protein
CCX80_RS00275	COG1309	transcriptional regulator
CCX80_RS00285	COG0697	spore germination
CCX80_RS00295	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CCX80_RS00400	COG0488	(ABC) transporter
CCX80_RS00420	COG1064	alcohol dehydrogenase
CCX80_RS00425	COG2814	Major facilitator Superfamily
CCX80_RS00430	COG0126	phosphoglycerate kinase activity
CCX80_RS00460	COG3590	peptidase
CCX80_RS00465	COG4608	Belongs to the ABC transporter superfamily
CCX80_RS00470	COG0444	Belongs to the ABC transporter superfamily
CCX80_RS00475	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CCX80_RS00480	COG0601	transmembrane transport
CCX80_RS00485	COG4166	transmembrane transport
CCX80_RS00490	COG0765	amino acid transport
CCX80_RS00495	COG0765	amino acid transport
CCX80_RS00500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CCX80_RS00505	COG1126	abc transporter atp-binding protein
CCX80_RS00510	COG1132	(ABC) transporter
CCX80_RS00515	COG1132	(ABC) transporter
CCX80_RS00525	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CCX80_RS00530	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CCX80_RS00535	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CCX80_RS00540	COG1959	2 iron, 2 sulfur cluster binding
CCX80_RS00545	COG1511	domain protein
CCX80_RS00550	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CCX80_RS00555	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CCX80_RS00575	COG0745	RESPONSE REGULATOR receiver
CCX80_RS00580	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CCX80_RS00595	COG0473	3-isopropylmalate dehydrogenase activity
CCX80_RS00605	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CCX80_RS00610	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CCX80_RS00620	COG0028	Belongs to the TPP enzyme family
CCX80_RS00625	COG1119	ATPase activity
CCX80_RS00630	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
CCX80_RS00635	COG2188	Transcriptional regulator
CCX80_RS00640	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CCX80_RS00650	COG0305	Participates in initiation and elongation during chromosome replication
CCX80_RS00655	COG0359	binds to the 23S rRNA
CCX80_RS00665	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CCX80_RS00670	COG0629	single-stranded DNA binding
CCX80_RS00675	COG0360	Binds together with S18 to 16S ribosomal RNA
CCX80_RS00680	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CCX80_RS00690	COG1122	ATPase activity
CCX80_RS00695	COG4720	Psort location CytoplasmicMembrane, score
CCX80_RS00705	COG0514	ATP-dependent DNA helicase (RecQ)
CCX80_RS00780	COG3623	hexulose-6-phosphate isomerase
CCX80_RS00815	COG0561	phosphatase activity
CCX80_RS00850	COG1757	Na H antiporter
CCX80_RS00860	COG1902	pentaerythritol trinitrate reductase activity
CCX80_RS00865	COG1733	regulation of RNA biosynthetic process
CCX80_RS00870	COG0667	Aldo Keto reductase
CCX80_RS00880	COG0667	Aldo Keto reductase
CCX80_RS00890	COG2814	Major facilitator Superfamily
CCX80_RS00900	COG1686	Belongs to the peptidase S11 family
CCX80_RS00910	COG0803	Belongs to the bacterial solute-binding protein 9 family
CCX80_RS00915	COG2226	methyltransferase
CCX80_RS00920	COG0318	PFAM AMP-dependent synthetase and ligase
CCX80_RS00930	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
CCX80_RS00960	COG0066	3-isopropylmalate dehydratase activity
CCX80_RS00965	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CCX80_RS00970	COG0473	3-isopropylmalate dehydrogenase activity
CCX80_RS00980	COG2151	metal-sulfur cluster biosynthetic enzyme
CCX80_RS00985	COG0719	Fe-S assembly protein
CCX80_RS00995	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CCX80_RS01000	COG0719	Fe-S assembly protein
CCX80_RS01005	COG0396	ATPase activity
CCX80_RS01015	COG0129	dihydroxy-acid dehydratase activity
CCX80_RS01020	COG2151	metal-sulfur cluster biosynthetic enzyme
CCX80_RS01035	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CCX80_RS01050	COG1983	PspC domain protein
CCX80_RS01065	COG0577	efflux transmembrane transporter activity
CCX80_RS01070	COG1136	(ABC) transporter
CCX80_RS01105	COG2855	membrane
CCX80_RS01110	COG0583	DNA-binding transcription factor activity
CCX80_RS01115	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CCX80_RS01130	COG0681	Belongs to the peptidase S26 family
CCX80_RS01135	COG0706	membrane insertase activity
CCX80_RS01140	COG0594	ribonuclease P activity
CCX80_RS01145	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CCX80_RS01150	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CCX80_RS01155	COG0446	pyridine nucleotide-disulphide oxidoreductase
CCX80_RS01165	COG2084	Dehydrogenase
CCX80_RS01170	COG0561	phosphatase activity
CCX80_RS01190	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CCX80_RS01195	COG0592	DNA-directed DNA polymerase activity
CCX80_RS01205	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CCX80_RS01210	COG0187	DNA topoisomerase II activity
CCX80_RS01220	COG0386	Belongs to the glutathione peroxidase family
CCX80_RS01250	COG1073	alpha beta
CCX80_RS01265	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CCX80_RS01270	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CCX80_RS01275	COG0436	Aminotransferase
CCX80_RS01375	COG2814	Major facilitator Superfamily
CCX80_RS01380	COG0647	UMP catabolic process
CCX80_RS01400	COG1368	sulfuric ester hydrolase activity
CCX80_RS01405	COG0438	transferase activity, transferring glycosyl groups
CCX80_RS01415	COG0564	pseudouridine synthase activity
CCX80_RS01420	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CCX80_RS01425	COG2217	Heavy metal translocating P-type atpase
CCX80_RS01435	COG1725	Transcriptional regulator
CCX80_RS01440	COG1131	(ABC) transporter
CCX80_RS01450	COG1131	(ABC) transporter
CCX80_RS01460	COG0656	L-ascorbic acid biosynthetic process
CCX80_RS01470	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CCX80_RS01475	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CCX80_RS01480	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CCX80_RS01485	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CCX80_RS01490	COG1881	PFAM PEBP family protein
CCX80_RS01505	COG0569	domain protein
CCX80_RS01515	COG0738	Major facilitator superfamily
CCX80_RS01550	COG3845	ABC transporter
CCX80_RS01555	COG4603	Belongs to the binding-protein-dependent transport system permease family
CCX80_RS01560	COG1079	Belongs to the binding-protein-dependent transport system permease family
CCX80_RS01575	COG4120	Belongs to the binding-protein-dependent transport system permease family
CCX80_RS01585	COG1396	sequence-specific DNA binding
CCX80_RS01660	COG0351	phosphomethylpyrimidine kinase
CCX80_RS01670	COG1053	succinate dehydrogenase
CCX80_RS01675	COG1131	(ABC) transporter
CCX80_RS01685	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CCX80_RS01690	COG0463	Glycosyl transferase, family 2
CCX80_RS01700	COG0446	pyridine nucleotide-disulphide oxidoreductase
CCX80_RS01720	COG0456	acetyltransferase
CCX80_RS01725	COG0765	amino acid transport
CCX80_RS01735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CCX80_RS01740	COG1473	amidohydrolase
CCX80_RS01745	COG3118	belongs to the thioredoxin family
CCX80_RS01750	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CCX80_RS01755	COG0531	amino acid
CCX80_RS01765	COG1464	Belongs to the NlpA lipoprotein family
CCX80_RS01775	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CCX80_RS01780	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CCX80_RS01785	COG1307	EDD domain protein, DegV family
CCX80_RS01790	COG1272	protein, Hemolysin III
CCX80_RS01805	COG2115	Belongs to the xylose isomerase family
CCX80_RS01820	COG1968	undecaprenyl-diphosphatase activity
CCX80_RS01835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CCX80_RS01840	COG0765	amino acid transport
CCX80_RS01845	COG0765	amino acid transport
CCX80_RS01850	COG1126	abc transporter atp-binding protein
CCX80_RS01855	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CCX80_RS01865	COG4720	Psort location CytoplasmicMembrane, score
CCX80_RS01870	COG0351	phosphomethylpyrimidine kinase
CCX80_RS01885	COG1454	alcohol dehydrogenase
CCX80_RS01885	COG1012	belongs to the aldehyde dehydrogenase family
CCX80_RS01890	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CCX80_RS01925	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CCX80_RS01935	COG0756	dUTP diphosphatase activity
CCX80_RS01950	COG1309	transcriptional regulator
CCX80_RS01955	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CCX80_RS01960	COG0215	cysteine-tRNA ligase activity
CCX80_RS02060	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CCX80_RS02065	COG0653	protein targeting
CCX80_RS02070	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CCX80_RS02075	COG0542	response to heat
CCX80_RS02085	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CCX80_RS02090	COG0049	tRNA binding
CCX80_RS02095	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CCX80_RS02100	COG2807	transmembrane transport
CCX80_RS02105	COG3842	ATPase activity
CCX80_RS02110	COG1177	transmembrane transport
CCX80_RS02115	COG1177	transmembrane transport
CCX80_RS02125	COG0051	transcription antitermination factor activity, RNA binding
CCX80_RS02130	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CCX80_RS02135	COG0088	Forms part of the polypeptide exit tunnel
CCX80_RS02140	COG0089	rRNA binding
CCX80_RS02145	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CCX80_RS02150	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CCX80_RS02155	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CCX80_RS02160	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CCX80_RS02165	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CCX80_RS02170	COG0255	Belongs to the universal ribosomal protein uL29 family
CCX80_RS02175	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CCX80_RS02180	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CCX80_RS02185	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CCX80_RS02190	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CCX80_RS02195	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CCX80_RS02200	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CCX80_RS02205	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CCX80_RS02210	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CCX80_RS02215	COG1841	ribosomal large subunit assembly
CCX80_RS02220	COG0200	Binds to the 23S rRNA
CCX80_RS02230	COG0563	adenylate kinase activity
CCX80_RS02235	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CCX80_RS02240	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CCX80_RS02245	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CCX80_RS02250	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CCX80_RS02255	COG0202	RNA polymerase activity
CCX80_RS02260	COG0203	ribosomal protein L17
CCX80_RS02265	COG0142	geranyltranstransferase activity
CCX80_RS02275	COG1122	ATPase activity
CCX80_RS02280	COG1122	ATPase activity
CCX80_RS02285	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CCX80_RS02290	COG0101	tRNA pseudouridine synthase activity
CCX80_RS02300	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CCX80_RS02305	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CCX80_RS02310	COG0583	DNA-binding transcription factor activity
CCX80_RS02315	COG1902	pentaerythritol trinitrate reductase activity
CCX80_RS02350	COG0149	triose-phosphate isomerase activity
CCX80_RS02355	COG0148	phosphopyruvate hydratase activity
CCX80_RS02370	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CCX80_RS02380	COG1739	Uncharacterized protein family UPF0029
CCX80_RS02385	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CCX80_RS02390	COG1040	competence protein
CCX80_RS02405	COG0588	phosphoglycerate mutase activity
CCX80_RS02410	COG1253	flavin adenine dinucleotide binding
CCX80_RS02415	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CCX80_RS02420	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CCX80_RS02425	COG1780	Probably involved in ribonucleotide reductase function
CCX80_RS02440	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CCX80_RS02455	COG1077	Cell shape determining protein MreB Mrl
CCX80_RS02465	COG0772	Belongs to the SEDS family
CCX80_RS02475	COG1181	Belongs to the D-alanine--D-alanine ligase family
CCX80_RS02485	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CCX80_RS02500	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CCX80_RS02505	COG0081	regulation of translation
CCX80_RS02510	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CCX80_RS02515	COG0222	ribosome binding
CCX80_RS02520	COG2813	Specifically methylates the guanine in position
CCX80_RS02525	COG0590	tRNA wobble adenosine to inosine editing
CCX80_RS02540	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CCX80_RS02545	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CCX80_RS02555	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CCX80_RS02560	COG3870	Protein conserved in bacteria
CCX80_RS02565	COG0470	DNA polymerase III
CCX80_RS02580	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CCX80_RS02600	COG1609	Transcriptional regulator
CCX80_RS02610	COG1621	beta-fructofuranosidase activity
CCX80_RS02615	COG1940	carbohydrate kinase activity
CCX80_RS02630	COG1428	Deoxynucleoside kinase
CCX80_RS02635	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CCX80_RS02640	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CCX80_RS02650	COG0492	ferredoxin-NADP+ reductase activity
CCX80_RS02660	COG1418	mRNA catabolic process
CCX80_RS02665	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CCX80_RS02665	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CCX80_RS02670	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CCX80_RS02670	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CCX80_RS02700	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CCX80_RS02710	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CCX80_RS02715	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CCX80_RS02725	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CCX80_RS02730	COG1028	Short-chain dehydrogenase reductase Sdr
CCX80_RS02735	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CCX80_RS02750	COG0439	Biotin carboxylase
CCX80_RS02755	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CCX80_RS02775	COG0525	valine-tRNA ligase activity
CCX80_RS02780	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CCX80_RS02795	COG0791	NLP P60 protein
CCX80_RS02795	COG1388	LysM domain
CCX80_RS02795	COG3103	Sh3 type 3 domain protein
CCX80_RS02805	COG0768	penicillin binding
CCX80_RS02810	COG0640	Transcriptional regulator
CCX80_RS02820	COG0577	efflux transmembrane transporter activity
CCX80_RS02820	COG1136	(ABC) transporter
CCX80_RS02825	COG1316	TRANSCRIPTIONal
CCX80_RS02850	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CCX80_RS02860	COG1914	H( )-stimulated, divalent metal cation uptake system
CCX80_RS02870	COG0640	Transcriptional regulator
CCX80_RS02885	COG1957	nucleoside hydrolase
CCX80_RS02890	COG0357	Ribosomal RNA small subunit methyltransferase G
CCX80_RS02895	COG1192	Involved in chromosome partitioning
CCX80_RS02900	COG1475	DNA binding
CCX80_RS02905	COG4481	Protein conserved in bacteria
CCX80_RS02910	COG0012	GTP binding
CCX80_RS02920	COG0745	RESPONSE REGULATOR receiver
CCX80_RS02925	COG2205	protein histidine kinase activity
CCX80_RS02935	COG0363	glucosamine-6-phosphate deaminase activity
CCX80_RS02940	COG0166	Belongs to the GPI family
CCX80_RS02950	COG3448	diguanylate cyclase activity
CCX80_RS02950	COG4175	Glycine betaine
CCX80_RS02970	COG4152	abc transporter atp-binding protein
CCX80_RS03005	COG0765	amino acid transport
CCX80_RS03010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CCX80_RS03015	COG0765	amino acid transport
CCX80_RS03020	COG1126	abc transporter atp-binding protein
CCX80_RS03025	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CCX80_RS03030	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CCX80_RS03035	COG1126	abc transporter atp-binding protein
CCX80_RS03040	COG2814	Major facilitator Superfamily
CCX80_RS03045	COG0343	queuine tRNA-ribosyltransferase activity
CCX80_RS03050	COG1862	Preprotein translocase
CCX80_RS03060	COG0392	lysyltransferase activity
CCX80_RS03060	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CCX80_RS03075	COG0406	alpha-ribazole phosphatase activity
CCX80_RS03090	COG1132	(ABC) transporter
CCX80_RS03095	COG1132	(ABC) transporter
CCX80_RS03100	COG0438	transferase activity, transferring glycosyl groups
CCX80_RS03120	COG1368	sulfuric ester hydrolase activity
CCX80_RS03125	COG0556	nucleotide-excision repair
CCX80_RS03130	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CCX80_RS03135	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CCX80_RS03140	COG1481	regulation of sporulation
CCX80_RS03145	COG0740	serine-type endopeptidase activity
CCX80_RS03155	COG0193	aminoacyl-tRNA hydrolase activity
CCX80_RS03160	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CCX80_RS03165	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CCX80_RS03175	COG0037	tRNA processing
CCX80_RS03185	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CCX80_RS03190	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CCX80_RS03195	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CCX80_RS03220	COG0217	transcriptional regulatory protein
CCX80_RS03225	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CCX80_RS03235	COG2252	PERMEase
CCX80_RS03240	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CCX80_RS03285	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CCX80_RS03295	COG2188	Transcriptional regulator
CCX80_RS03305	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CCX80_RS03315	COG1464	Belongs to the NlpA lipoprotein family
CCX80_RS03350	COG1744	ABC transporter substrate-binding protein PnrA-like
CCX80_RS03355	COG0765	amino acid transport
CCX80_RS03360	COG1126	abc transporter atp-binding protein
CCX80_RS03365	COG0765	amino acid transport
CCX80_RS03395	COG1733	regulation of RNA biosynthetic process
CCX80_RS03400	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CCX80_RS03405	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CCX80_RS03405	COG0072	phenylalanine-tRNA ligase activity
CCX80_RS03410	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CCX80_RS03415	COG0254	rRNA binding
CCX80_RS03420	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CCX80_RS03425	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CCX80_RS03445	COG2814	Major facilitator Superfamily
CCX80_RS03450	COG2003	Belongs to the UPF0758 family
CCX80_RS03455	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CCX80_RS03460	COG2131	deaminase
CCX80_RS03465	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CCX80_RS03470	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CCX80_RS03480	COG4537	Required for transformation and DNA binding
CCX80_RS03510	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CCX80_RS03520	COG4975	Glucose uptake
CCX80_RS03525	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CCX80_RS03560	COG0683	leucine binding
CCX80_RS03565	COG0559	Belongs to the binding-protein-dependent transport system permease family
CCX80_RS03575	COG0411	ABC transporter
CCX80_RS03585	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CCX80_RS03590	COG0351	phosphomethylpyrimidine kinase
CCX80_RS03595	COG0352	thiamine-phosphate diphosphorylase activity
CCX80_RS03600	COG1012	belongs to the aldehyde dehydrogenase family
CCX80_RS03640	COG4493	Belongs to the UPF0637 family
CCX80_RS03650	COG1609	Transcriptional regulator
CCX80_RS03670	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CCX80_RS03680	COG0308	aminopeptidase N
CCX80_RS03700	COG1263	PTS System
CCX80_RS03700	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CCX80_RS03700	COG2190	(PTS) system
CCX80_RS03705	COG0366	Alpha amylase catalytic
CCX80_RS03710	COG2188	Transcriptional regulator
CCX80_RS03715	COG1078	dGTPase activity
CCX80_RS03725	COG3343	RNA polymerase activity
CCX80_RS03735	COG1113	amino acid transport
CCX80_RS03740	COG1268	BioY protein
CCX80_RS03750	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CCX80_RS03750	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CCX80_RS03755	COG0504	CTP synthase activity
CCX80_RS03760	COG0322	excinuclease ABC activity
CCX80_RS03765	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CCX80_RS03770	COG0028	Belongs to the TPP enzyme family
CCX80_RS03780	COG2309	aminopeptidase activity
CCX80_RS03790	COG0673	inositol 2-dehydrogenase activity
CCX80_RS03795	COG0513	Belongs to the DEAD box helicase family
CCX80_RS03810	COG0237	dephospho-CoA kinase activity
CCX80_RS03820	COG1484	DNA-dependent DNA replication
CCX80_RS03845	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CCX80_RS03850	COG0416	fatty acid biosynthetic process
CCX80_RS03855	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CCX80_RS03860	COG3091	SprT-like family
CCX80_RS03865	COG0561	phosphatase activity
CCX80_RS03885	COG1609	Transcriptional regulator
CCX80_RS03895	COG2814	Major facilitator Superfamily
CCX80_RS03910	COG3527	Alpha-acetolactate decarboxylase
CCX80_RS03915	COG1737	Transcriptional regulator
CCX80_RS03920	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CCX80_RS03935	COG0531	amino acid
CCX80_RS03945	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CCX80_RS03950	COG4472	Bacterial protein of unknown function (DUF965)
CCX80_RS03955	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CCX80_RS03960	COG3906	Belongs to the UPF0473 family
CCX80_RS03965	COG1271	oxidase subunit
CCX80_RS03970	COG1294	oxidase, subunit
CCX80_RS03975	COG4988	ABC transporter
CCX80_RS03980	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CCX80_RS03985	COG1705	Flagellar rod assembly protein muramidase FlgJ
CCX80_RS03990	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CCX80_RS04005	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CCX80_RS04020	COG0542	response to heat
CCX80_RS04025	COG1077	Cell shape determining protein MreB Mrl
CCX80_RS04040	COG0765	amino acid transport
CCX80_RS04060	COG0612	Peptidase, M16
CCX80_RS04065	COG0612	Peptidase, M16
CCX80_RS04070	COG1426	Protein conserved in bacteria
CCX80_RS04075	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CCX80_RS04080	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CCX80_RS04085	COG0745	RESPONSE REGULATOR receiver
CCX80_RS04090	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CCX80_RS04105	COG0573	inorganic phosphate transmembrane transporter activity
CCX80_RS04110	COG0581	inorganic phosphate transmembrane transporter activity
CCX80_RS04115	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CCX80_RS04120	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CCX80_RS04125	COG0704	Plays a role in the regulation of phosphate uptake
CCX80_RS04135	COG1950	PFAM Membrane protein of
CCX80_RS04140	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CCX80_RS04145	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CCX80_RS04150	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CCX80_RS04155	COG0492	ferredoxin-NADP+ reductase activity
CCX80_RS04170	COG1063	alcohol dehydrogenase
CCX80_RS04175	COG1609	Transcriptional regulator
CCX80_RS04185	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CCX80_RS04190	COG0335	large ribosomal subunit rRNA binding
CCX80_RS04195	COG1719	4-vinyl reductase, 4VR
CCX80_RS04200	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CCX80_RS04205	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CCX80_RS04215	COG2255	four-way junction helicase activity
CCX80_RS04225	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CCX80_RS04230	COG0584	glycerophosphoryl diester phosphodiesterase
CCX80_RS04235	COG0632	four-way junction helicase activity
CCX80_RS04240	COG1428	Deoxynucleoside kinase
CCX80_RS04245	COG1970	mechanosensitive ion channel activity
CCX80_RS04250	COG0577	efflux transmembrane transporter activity
CCX80_RS04255	COG1136	(ABC) transporter
CCX80_RS04260	COG4684	Psort location CytoplasmicMembrane, score
CCX80_RS04270	COG4684	Psort location CytoplasmicMembrane, score
CCX80_RS04290	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CCX80_RS04295	COG1126	abc transporter atp-binding protein
CCX80_RS04300	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CCX80_RS04310	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CCX80_RS04320	COG0671	phosphoesterase, PA-phosphatase related
CCX80_RS04325	COG0495	leucyl-tRNA aminoacylation
CCX80_RS04330	COG2244	polysaccharide biosynthetic process
CCX80_RS04345	COG1704	LemA family
CCX80_RS04350	COG0501	Belongs to the peptidase M48B family
CCX80_RS04355	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CCX80_RS04360	COG1942	4-Oxalocrotonate Tautomerase
CCX80_RS04370	COG3237	CsbD-like
CCX80_RS04375	COG0516	GMP reductase activity
CCX80_RS04375	COG0517	IMP dehydrogenase activity
CCX80_RS04380	COG0516	GMP reductase activity
CCX80_RS04380	COG0517	IMP dehydrogenase activity
CCX80_RS04415	COG3331	DNA recombination
CCX80_RS04425	COG4474	Belongs to the UPF0398 family
CCX80_RS04430	COG3599	regulation of cell shape
CCX80_RS04440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CCX80_RS04445	COG2706	6-phosphogluconolactonase activity
CCX80_RS04450	COG0628	permease
CCX80_RS04465	COG1674	ftsk spoiiie
CCX80_RS04465	COG1280	lysine exporter protein (LysE YggA)
CCX80_RS04470	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CCX80_RS04475	COG1113	amino acid transport
CCX80_RS04480	COG0586	Pfam SNARE associated Golgi protein
CCX80_RS04490	COG3001	Fructosamine kinase
CCX80_RS04500	COG2171	N-acyltransferase activity
CCX80_RS04505	COG1473	amidohydrolase
CCX80_RS04510	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CCX80_RS04515	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CCX80_RS04525	COG3557	Belongs to the UPF0374 family
CCX80_RS04530	COG0705	Rhomboid family
CCX80_RS04540	COG1940	carbohydrate kinase activity
CCX80_RS04550	COG2357	RelA SpoT domain protein
CCX80_RS04555	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CCX80_RS04560	COG0564	pseudouridine synthase activity
CCX80_RS04565	COG2239	Acts as a magnesium transporter
CCX80_RS04575	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CCX80_RS04580	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CCX80_RS04585	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CCX80_RS04590	COG4589	Belongs to the CDS family
CCX80_RS04595	COG0750	zinc metalloprotease
CCX80_RS04600	COG0442	prolyl-tRNA aminoacylation
CCX80_RS04605	COG2176	DNA-directed DNA polymerase activity
CCX80_RS04620	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CCX80_RS04620	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
CCX80_RS04625	COG1744	ABC transporter substrate-binding protein PnrA-like
CCX80_RS04640	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CCX80_RS04645	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CCX80_RS04655	COG0667	Aldo Keto reductase
CCX80_RS04660	COG0151	Belongs to the GarS family
CCX80_RS04665	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CCX80_RS04675	COG1278	Cold shock
CCX80_RS04680	COG0494	nUDIX hydrolase
CCX80_RS04690	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CCX80_RS04695	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CCX80_RS04700	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CCX80_RS04720	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CCX80_RS04720	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CCX80_RS04725	COG3764	Sortase (surface protein transpeptidase)
CCX80_RS04735	COG0789	Transcriptional regulator
CCX80_RS04740	COG0174	glutamine synthetase
CCX80_RS04745	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CCX80_RS04750	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CCX80_RS04755	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CCX80_RS04760	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CCX80_RS04770	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CCX80_RS04780	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CCX80_RS04785	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CCX80_RS04790	COG0138	bifunctional purine biosynthesis protein purh
CCX80_RS04795	COG0420	3'-5' exonuclease activity
CCX80_RS04800	COG4717	serine-type aminopeptidase activity
CCX80_RS04820	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CCX80_RS04830	COG0095	Lipoate-protein ligase
CCX80_RS04845	COG0508	dehydrogenase complex catalyzes the overall conversion of
CCX80_RS04855	COG2267	carboxylic ester hydrolase activity
CCX80_RS04880	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CCX80_RS04885	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CCX80_RS04895	COG0351	phosphomethylpyrimidine kinase
CCX80_RS04905	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CCX80_RS04925	COG0617	tRNA 3'-terminal CCA addition
CCX80_RS04935	COG1307	EDD domain protein, DegV family
CCX80_RS04940	COG1957	nucleoside hydrolase
CCX80_RS04950	COG2755	lipolytic protein G-D-S-L family
CCX80_RS04960	COG4479	Belongs to the UPF0346 family
CCX80_RS04965	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CCX80_RS04970	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CCX80_RS04980	COG1122	ATPase activity
CCX80_RS04995	COG2384	SAM-dependent methyltransferase
CCX80_RS05000	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CCX80_RS05015	COG0587	DNA-directed DNA polymerase activity
CCX80_RS05025	COG0004	ammonium transporteR
CCX80_RS05030	COG1702	phosphate starvation-inducible protein PhoH
CCX80_RS05035	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CCX80_RS05045	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CCX80_RS05050	COG1381	Involved in DNA repair and RecF pathway recombination
CCX80_RS05055	COG0252	asparaginase activity
CCX80_RS05065	COG0527	aspartate kinase activity
CCX80_RS05070	COG0083	homoserine kinase activity
CCX80_RS05075	COG0460	homoserine dehydrogenase
CCX80_RS05080	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CCX80_RS05085	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CCX80_RS05090	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CCX80_RS05095	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CCX80_RS05120	COG1609	Transcriptional regulator
CCX80_RS05125	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CCX80_RS05145	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CCX80_RS05145	COG0517	IMP dehydrogenase activity
CCX80_RS05150	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CCX80_RS05165	COG1121	(ABC) transporter
CCX80_RS05170	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CCX80_RS05190	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CCX80_RS05195	COG0415	Belongs to the DNA photolyase family
CCX80_RS05200	COG0577	efflux transmembrane transporter activity
CCX80_RS05215	COG2409	Drug exporters of the RND superfamily
CCX80_RS05215	COG1033	growth of symbiont in host cell
CCX80_RS05235	COG0067	glutamate synthase
CCX80_RS05235	COG0069	glutamate synthase activity
CCX80_RS05235	COG0070	glutamate synthase
CCX80_RS05240	COG0493	'glutamate synthase
CCX80_RS05255	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CCX80_RS05255	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CCX80_RS05260	COG0307	riboflavin synthase, alpha
CCX80_RS05270	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CCX80_RS05275	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CCX80_RS05280	COG2814	Major facilitator Superfamily
CCX80_RS05290	COG1609	Transcriptional regulator
CCX80_RS05315	COG0745	RESPONSE REGULATOR receiver
CCX80_RS05320	COG5002	protein histidine kinase activity
CCX80_RS05325	COG1136	(ABC) transporter
CCX80_RS05335	COG0583	DNA-binding transcription factor activity
CCX80_RS05345	COG1045	serine acetyltransferase
CCX80_RS05355	COG0667	Aldo Keto reductase
CCX80_RS05370	COG1874	Beta-galactosidase
CCX80_RS05400	COG1609	Transcriptional regulator
CCX80_RS05405	COG2160	L-arabinose isomerase activity
CCX80_RS05430	COG5263	repeat protein
CCX80_RS05430	COG0366	Alpha amylase catalytic
CCX80_RS05435	COG1028	Short-chain dehydrogenase reductase Sdr
CCX80_RS05450	COG2261	transglycosylase associated protein
CCX80_RS05475	COG2261	transglycosylase associated protein
CCX80_RS05485	COG2814	Major facilitator Superfamily
CCX80_RS05490	COG5039	Polysaccharide pyruvyl transferase
CCX80_RS05515	COG1472	Belongs to the glycosyl hydrolase 3 family
CCX80_RS05540	COG2190	(PTS) system
CCX80_RS05540	COG2211	Major facilitator Superfamily
CCX80_RS05545	COG1609	Transcriptional regulator
CCX80_RS05555	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CCX80_RS05560	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
CCX80_RS05590	COG3534	alpha-L-arabinofuranosidase
CCX80_RS05600	COG1609	Transcriptional regulator
CCX80_RS05615	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CCX80_RS05625	COG0366	Alpha amylase catalytic
CCX80_RS05635	COG0366	Alpha amylase catalytic
CCX80_RS05640	COG3711	transcriptional antiterminator
CCX80_RS05650	COG2723	6-phospho-beta-galactosidase activity
CCX80_RS05660	COG1956	GAF domain-containing protein
CCX80_RS05665	COG2244	polysaccharide biosynthetic process
CCX80_RS05670	COG1609	Transcriptional regulator
CCX80_RS05700	COG1215	transferase activity, transferring glycosyl groups
CCX80_RS05715	COG0300	oxidoreductase activity
CCX80_RS05725	COG0477	Major facilitator Superfamily
CCX80_RS05730	COG1063	alcohol dehydrogenase
CCX80_RS05745	COG1573	uracil-dna glycosylase
CCX80_RS05750	COG4720	Psort location CytoplasmicMembrane, score
CCX80_RS05765	COG0693	protein deglycase activity
CCX80_RS05775	COG0436	Aminotransferase
CCX80_RS05780	COG1028	Short-chain dehydrogenase reductase Sdr
CCX80_RS05785	COG2610	gluconate transmembrane transporter activity
CCX80_RS05790	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CCX80_RS05795	COG1619	proteins homologs of microcin C7 resistance protein MccF
CCX80_RS05805	COG2723	6-phospho-beta-galactosidase activity
CCX80_RS05815	COG3711	transcriptional antiterminator
CCX80_RS05815	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CCX80_RS05820	COG1447	Phosphotransferase system cellobiose-specific component IIA
CCX80_RS05830	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CCX80_RS05850	COG1028	Short-chain dehydrogenase reductase Sdr
CCX80_RS05860	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CCX80_RS05880	COG2723	6-phospho-beta-galactosidase activity
CCX80_RS05895	COG1733	regulation of RNA biosynthetic process
CCX80_RS05900	COG1846	Transcriptional regulator
CCX80_RS05920	COG1442	glycosyl transferase family 8
CCX80_RS05925	COG1121	(ABC) transporter
CCX80_RS05930	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CCX80_RS05940	COG3527	Alpha-acetolactate decarboxylase
CCX80_RS05950	COG0745	RESPONSE REGULATOR receiver
CCX80_RS05955	COG5002	protein histidine kinase activity
CCX80_RS05975	COG1316	TRANSCRIPTIONal
CCX80_RS05980	COG1846	Transcriptional regulator
CCX80_RS05985	COG2814	Major facilitator Superfamily
CCX80_RS05990	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CCX80_RS06000	COG0656	L-ascorbic acid biosynthetic process
CCX80_RS06005	COG0789	Transcriptional regulator
CCX80_RS06010	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CCX80_RS06015	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CCX80_RS06020	COG0300	oxidoreductase activity
CCX80_RS06030	COG2364	Membrane
CCX80_RS06035	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CCX80_RS06050	COG0028	Belongs to the TPP enzyme family
CCX80_RS06055	COG0071	Belongs to the small heat shock protein (HSP20) family
CCX80_RS06060	COG0702	epimerase
CCX80_RS06075	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CCX80_RS06085	COG3340	Belongs to the peptidase S51 family
CCX80_RS06095	COG0384	phenazine biosynthesis protein PhzF
CCX80_RS06105	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CCX80_RS06110	COG0511	ligase activity, forming carbon-carbon bonds
CCX80_RS06120	COG4336	lyase activity
CCX80_RS06125	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CCX80_RS06130	COG1914	H( )-stimulated, divalent metal cation uptake system
CCX80_RS06135	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CCX80_RS06160	COG2801	Transposase and inactivated derivatives
CCX80_RS06185	COG2017	converts alpha-aldose to the beta-anomer
CCX80_RS06190	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CCX80_RS06200	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CCX80_RS06200	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CCX80_RS06220	COG0281	malic enzyme
CCX80_RS06250	COG2267	carboxylic ester hydrolase activity
CCX80_RS06365	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CCX80_RS06375	COG4122	O-methyltransferase activity
CCX80_RS06395	COG0542	response to heat
CCX80_RS06465	COG2364	Membrane
CCX80_RS06500	COG2826	transposase and inactivated derivatives, IS30 family
CCX80_RS06515	COG3158	transport of potassium into the cell
CCX80_RS06575	COG0433	COG0433 Predicted ATPase
CCX80_RS06600	COG1674	ftsk spoiiie
CCX80_RS06625	COG1511	domain protein
CCX80_RS06630	COG1959	2 iron, 2 sulfur cluster binding
CCX80_RS06645	COG2826	transposase and inactivated derivatives, IS30 family
CCX80_RS06665	COG0131	Imidazoleglycerol-phosphate dehydratase
CCX80_RS06665	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CCX80_RS06700	COG2197	response regulator
CCX80_RS06705	COG4585	Histidine kinase
CCX80_RS06710	COG2409	Drug exporters of the RND superfamily
CCX80_RS06725	COG2814	Major facilitator Superfamily
CCX80_RS06735	COG1028	Short-chain dehydrogenase reductase Sdr
CCX80_RS06745	COG0318	PFAM AMP-dependent synthetase and ligase
CCX80_RS06755	COG1116	anion transmembrane transporter activity
CCX80_RS06760	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CCX80_RS06765	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CCX80_RS06780	COG2104	thiamine diphosphate biosynthetic process
CCX80_RS06780	COG2022	thiamine diphosphate biosynthetic process
CCX80_RS06785	COG0352	thiamine-phosphate diphosphorylase activity
CCX80_RS06790	COG0710	3-dehydroquinate dehydratase activity
CCX80_RS06800	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CCX80_RS06805	COG0287	Prephenate dehydrogenase
CCX80_RS06810	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CCX80_RS06815	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CCX80_RS06820	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CCX80_RS06825	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CCX80_RS06835	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CCX80_RS06840	COG0512	Glutamine amidotransferase of anthranilate synthase
CCX80_RS06845	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CCX80_RS06850	COG0159	tryptophan synthase activity
CCX80_RS06860	COG0134	indole-3-glycerol-phosphate synthase activity
CCX80_RS06865	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CCX80_RS06890	COG2848	UPF0210 protein
CCX80_RS06910	COG3425	synthase
CCX80_RS06915	COG0488	(ABC) transporter
CCX80_RS06925	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CCX80_RS06930	COG2264	protein methyltransferase activity
CCX80_RS06950	COG0673	inositol 2-dehydrogenase activity
CCX80_RS06955	COG0751	glycine-tRNA ligase activity
CCX80_RS06960	COG0752	glycyl-tRNA synthetase alpha subunit
CCX80_RS06970	COG0233	cytoplasmic translational termination
CCX80_RS06975	COG0528	UMP kinase activity
CCX80_RS06980	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CCX80_RS06985	COG0052	Belongs to the universal ribosomal protein uS2 family
CCX80_RS06990	COG2827	Endonuclease containing a URI domain
CCX80_RS06995	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CCX80_RS07000	COG0204	Acyl-transferase
CCX80_RS07005	COG3763	UPF0154 protein
CCX80_RS07010	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CCX80_RS07015	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CCX80_RS07020	COG0284	orotidine-5'-phosphate decarboxylase activity
CCX80_RS07025	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CCX80_RS07030	COG0505	Belongs to the CarA family
CCX80_RS07035	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CCX80_RS07040	COG0540	Belongs to the ATCase OTCase family
CCX80_RS07050	COG3679	Belongs to the UPF0342 family
CCX80_RS07055	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CCX80_RS07060	COG1438	arginine binding
CCX80_RS07065	COG0018	arginyl-trna synthetase
CCX80_RS07075	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CCX80_RS07110	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CCX80_RS07120	COG1131	(ABC) transporter
CCX80_RS07125	COG0537	adenosine 5'-monophosphoramidase activity
CCX80_RS07135	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CCX80_RS07145	COG0436	Aminotransferase
CCX80_RS07150	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CCX80_RS07155	COG1126	abc transporter atp-binding protein
CCX80_RS07160	COG0765	amino acid transport
CCX80_RS07165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CCX80_RS07170	COG0626	cystathionine gamma-synthase activity
CCX80_RS07180	COG1028	Short-chain dehydrogenase reductase Sdr
CCX80_RS07190	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CCX80_RS07195	COG0358	DNA primase activity
CCX80_RS07200	COG2826	transposase and inactivated derivatives, IS30 family
CCX80_RS07420	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CCX80_RS07440	COG0745	RESPONSE REGULATOR receiver
CCX80_RS07445	COG2205	protein histidine kinase activity
CCX80_RS07450	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CCX80_RS07480	COG2801	Transposase and inactivated derivatives
CCX80_RS07545	COG3716	PTS system mannose fructose sorbose family IID component
CCX80_RS07575	COG0758	DNA mediated transformation
CCX80_RS07580	COG0488	(ABC) transporter
CCX80_RS07585	COG0167	dihydroorotate dehydrogenase activity
CCX80_RS07590	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CCX80_RS07595	COG0860	N-Acetylmuramoyl-L-alanine amidase
CCX80_RS07605	COG2183	response to ionizing radiation
CCX80_RS07615	COG1970	mechanosensitive ion channel activity
CCX80_RS07625	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CCX80_RS07630	COG0626	cystathionine gamma-synthase activity
CCX80_RS07635	COG1045	serine acetyltransferase
CCX80_RS07640	COG0776	regulation of translation
CCX80_RS07645	COG1160	GTP binding
CCX80_RS07650	COG0539	negative regulation of cytoplasmic translation
CCX80_RS07665	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CCX80_RS07670	COG1187	pseudouridine synthase activity
CCX80_RS07675	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CCX80_RS07680	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CCX80_RS07690	COG4974	Belongs to the 'phage' integrase family
CCX80_RS07695	COG2996	Protein conserved in bacteria
CCX80_RS07700	COG1610	YqeY-like protein
CCX80_RS07705	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CCX80_RS07710	COG0477	Major facilitator Superfamily
CCX80_RS07715	COG2508	Transcriptional regulator
CCX80_RS07720	COG1113	amino acid transport
CCX80_RS07725	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CCX80_RS07730	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CCX80_RS07735	COG0124	histidyl-tRNA synthetase
CCX80_RS07740	COG2017	converts alpha-aldose to the beta-anomer
CCX80_RS07745	COG2207	Transcriptional regulator
CCX80_RS07750	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CCX80_RS07760	COG0667	Aldo Keto reductase
CCX80_RS07765	COG3250	beta-galactosidase activity
CCX80_RS07775	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CCX80_RS07780	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CCX80_RS07790	COG4470	Protein conserved in bacteria
CCX80_RS07795	COG0737	Belongs to the 5'-nucleotidase family
CCX80_RS07805	COG0006	proline dipeptidase activity
CCX80_RS07810	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CCX80_RS07815	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CCX80_RS07855	COG1247	-acetyltransferase
CCX80_RS07860	COG2962	Rard protein
CCX80_RS07885	COG1217	gtp-binding protein TYPA
CCX80_RS07890	COG0483	inositol monophosphate 1-phosphatase activity
CCX80_RS07895	COG4476	Belongs to the UPF0223 family
CCX80_RS07900	COG0242	peptide deformylase activity
CCX80_RS07905	COG0484	heat shock protein binding
CCX80_RS07910	COG0443	Heat shock 70 kDa protein
CCX80_RS07915	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CCX80_RS07920	COG1420	regulation of RNA biosynthetic process
CCX80_RS07925	COG0196	riboflavin kinase activity
CCX80_RS07930	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CCX80_RS07940	COG0436	Aminotransferase
CCX80_RS07945	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CCX80_RS07950	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CCX80_RS07960	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CCX80_RS07965	COG0195	Participates in both transcription termination and antitermination
CCX80_RS07970	COG0779	Required for maturation of 30S ribosomal subunits
CCX80_RS07975	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CCX80_RS07980	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CCX80_RS07985	COG1227	inorganic diphosphatase activity
CCX80_RS08005	COG1490	D-aminoacyl-tRNA deacylase activity
CCX80_RS08010	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CCX80_RS08030	COG0505	Belongs to the CarA family
CCX80_RS08035	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CCX80_RS08040	COG0564	pseudouridine synthase activity
CCX80_RS08050	COG0328	RNA-DNA hybrid ribonuclease activity
CCX80_RS08060	COG0436	Aminotransferase
CCX80_RS08065	COG0116	Belongs to the methyltransferase superfamily
CCX80_RS08080	COG0017	Asparaginyl-tRNA synthetase
CCX80_RS08095	COG1199	ATP-dependent helicase activity
CCX80_RS08095	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CCX80_RS08115	COG1304	FMN binding
CCX80_RS08125	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CCX80_RS08130	COG2116	formate transmembrane transporter activity
CCX80_RS08135	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CCX80_RS08140	COG0716	FMN binding
CCX80_RS08150	COG1216	Glycosyl transferase, family 2
CCX80_RS08180	COG0463	Glycosyl transferase, family 2
CCX80_RS08185	COG0562	UDP-galactopyranose mutase
CCX80_RS08205	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CCX80_RS08220	COG1621	beta-fructofuranosidase activity
CCX80_RS08270	COG1088	dTDP-glucose 4,6-dehydratase activity
CCX80_RS08280	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CCX80_RS08310	COG0463	Glycosyl transferase, family 2
CCX80_RS08310	COG1216	Glycosyl transferase, family 2
CCX80_RS08315	COG0463	Glycosyl transferase, family 2
CCX80_RS08335	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CCX80_RS08340	COG0489	protein tyrosine kinase activity
CCX80_RS08355	COG0024	Methionine aminopeptidase
CCX80_RS08360	COG1316	TRANSCRIPTIONal
CCX80_RS08365	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CCX80_RS08375	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CCX80_RS08380	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CCX80_RS08400	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CCX80_RS08405	COG3142	Participates in the control of copper homeostasis
CCX80_RS08720	COG0582	viral genome integration into host DNA
CCX80_RS08745	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
CCX80_RS08755	COG0165	Argininosuccinate lyase
CCX80_RS08760	COG0137	argininosuccinate synthase activity
CCX80_RS08765	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CCX80_RS08770	COG0217	transcriptional regulatory protein
CCX80_RS08780	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CCX80_RS08785	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CCX80_RS08795	COG0280	phosphate acetyltransferase
CCX80_RS08800	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CCX80_RS08830	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CCX80_RS08835	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CCX80_RS08835	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CCX80_RS08840	COG1234	tRNA 3'-trailer cleavage
CCX80_RS08845	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CCX80_RS08850	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CCX80_RS08855	COG0336	Belongs to the RNA methyltransferase TrmD family
CCX80_RS08860	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CCX80_RS08870	COG1074	ATP-dependent DNA helicase activity
CCX80_RS08875	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
CCX80_RS08890	COG0228	four-way junction DNA binding
CCX80_RS08900	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CCX80_RS08915	COG0762	integral membrane protein
CCX80_RS08920	COG1799	cell septum assembly
CCX80_RS08935	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CCX80_RS08940	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CCX80_RS08945	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CCX80_RS08950	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CCX80_RS08955	COG0768	penicillin binding
CCX80_RS08965	COG0275	rRNA processing
CCX80_RS08970	COG2001	Belongs to the MraZ family
CCX80_RS08985	COG1461	Dihydroxyacetone kinase
CCX80_RS08995	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CCX80_RS09000	COG3118	belongs to the thioredoxin family
CCX80_RS09005	COG1564	THIamine pyrophosphokinase
CCX80_RS09010	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CCX80_RS09015	COG1162	GTPase activity
CCX80_RS09020	COG2815	serine threonine protein kinase
CCX80_RS09020	COG0515	serine threonine protein kinase
CCX80_RS09025	COG0631	protein serine/threonine phosphatase activity
CCX80_RS09030	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CCX80_RS09030	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CCX80_RS09035	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CCX80_RS09040	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CCX80_RS09055	COG3201	nicotinamide mononucleotide transporter
CCX80_RS09060	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CCX80_RS09065	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CCX80_RS09070	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CCX80_RS09080	COG4974	Belongs to the 'phage' integrase family
CCX80_RS09085	COG1373	ATPase (AAA superfamily
CCX80_RS09105	COG0544	peptidyl-prolyl cis-trans isomerase activity
CCX80_RS09125	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CCX80_RS09130	COG0708	Exodeoxyribonuclease III
CCX80_RS09135	COG2176	DNA-directed DNA polymerase activity
CCX80_RS09140	COG0456	acetyltransferase
CCX80_RS09145	COG0802	atpase or kinase
CCX80_RS09180	COG0602	queuosine metabolic process
CCX80_RS09185	COG1328	CTP reductase activity
CCX80_RS09190	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CCX80_RS09195	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CCX80_RS09210	COG4172	Belongs to the ABC transporter superfamily
CCX80_RS09225	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CCX80_RS09230	COG0140	phosphoribosyl-ATP diphosphatase activity
CCX80_RS09235	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CCX80_RS09240	COG0107	imidazoleglycerol-phosphate synthase activity
CCX80_RS09245	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CCX80_RS09255	COG0131	Imidazoleglycerol-phosphate dehydratase
CCX80_RS09260	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CCX80_RS09280	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CCX80_RS09285	COG0561	phosphatase activity
CCX80_RS09295	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CCX80_RS09305	COG0552	protein localization to endoplasmic reticulum
CCX80_RS09310	COG1196	nuclear chromosome segregation
CCX80_RS09315	COG0571	ribonuclease III activity
CCX80_RS09320	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CCX80_RS09340	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CCX80_RS09345	COG0105	UTP biosynthetic process
CCX80_RS09350	COG4807	Protein conserved in bacteria
CCX80_RS09355	COG3237	CsbD-like
CCX80_RS09360	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CCX80_RS09365	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CCX80_RS09370	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CCX80_RS09375	COG1597	lipid kinase activity
CCX80_RS09380	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CCX80_RS09385	COG0154	amidase activity
CCX80_RS09390	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CCX80_RS09395	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CCX80_RS09400	COG0268	Binds directly to 16S ribosomal RNA
CCX80_RS09405	COG0513	Belongs to the DEAD box helicase family
CCX80_RS09410	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CCX80_RS09415	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CCX80_RS09420	COG1466	dna polymerase III delta subunit
CCX80_RS09425	COG2333	competence protein COMEC
CCX80_RS09425	COG0658	competence protein
CCX80_RS09430	COG1555	photosystem II stabilization
CCX80_RS09430	COG1596	polysaccharide export
CCX80_RS09435	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CCX80_RS09440	COG0742	ribosomal rna small subunit methyltransferase
CCX80_RS09445	COG4471	UPF0298 protein
CCX80_RS09450	COG0772	Belongs to the SEDS family
CCX80_RS09455	COG1363	Peptidase, m42
CCX80_RS09460	COG0588	phosphoglycerate mutase activity
CCX80_RS09465	COG0534	Mate efflux family protein
CCX80_RS09470	COG2252	PERMEase
CCX80_RS09475	COG0497	DNA recombination
CCX80_RS09480	COG1438	arginine binding
CCX80_RS09485	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CCX80_RS09490	COG0142	geranyltranstransferase activity
CCX80_RS09495	COG1722	exodeoxyribonuclease VII activity
CCX80_RS09500	COG1570	exodeoxyribonuclease VII activity
CCX80_RS09515	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CCX80_RS09520	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CCX80_RS09525	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CCX80_RS09530	COG1121	(ABC) transporter
CCX80_RS09540	COG4466	Protein conserved in bacteria
CCX80_RS09545	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CCX80_RS09550	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CCX80_RS09555	COG0084	hydrolase, TatD family'
CCX80_RS09560	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CCX80_RS09570	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CCX80_RS09580	COG1611	Belongs to the LOG family
CCX80_RS09585	COG5503	Protein of unknown function (DUF1447)
CCX80_RS09695	COG0740	serine-type endopeptidase activity
CCX80_RS09870	COG3152	Membrane
CCX80_RS09880	COG1892	Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four- carbon dicarboxylic acid source for the tricarboxylic acid cycle
CCX80_RS09895	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CCX80_RS09905	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CCX80_RS09910	COG0584	glycerophosphoryl diester phosphodiesterase
CCX80_RS09925	COG4862	establishment of competence for transformation
CCX80_RS09930	COG1393	Belongs to the ArsC family
CCX80_RS09960	COG1098	S1 RNA binding domain
CCX80_RS09970	COG1758	RNA polymerase activity
CCX80_RS09975	COG0194	GDP metabolic process
CCX80_RS09995	COG1193	negative regulation of DNA recombination
CCX80_RS10015	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CCX80_RS10030	COG1418	mRNA catabolic process
CCX80_RS10035	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CCX80_RS10040	COG0557	exoribonuclease II activity
CCX80_RS10050	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CCX80_RS10055	COG0706	membrane insertase activity
CCX80_RS10060	COG1254	Belongs to the acylphosphatase family
CCX80_RS10065	COG5002	protein histidine kinase activity
CCX80_RS10070	COG0745	RESPONSE REGULATOR receiver
CCX80_RS10085	COG2226	methyltransferase
CCX80_RS10090	COG0799	negative regulation of ribosome biogenesis
CCX80_RS10095	COG1713	HD superfamily hydrolase involved in NAD metabolism
CCX80_RS10100	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CCX80_RS10110	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CCX80_RS10115	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
CCX80_RS10140	COG1959	2 iron, 2 sulfur cluster binding
CCX80_RS10145	COG5263	repeat protein
CCX80_RS10145	COG0366	Alpha amylase catalytic
CCX80_RS10195	COG2323	membrane
CCX80_RS10215	COG0459	protein refolding
CCX80_RS10220	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CCX80_RS10235	COG3716	PTS system mannose fructose sorbose family IID component
CCX80_RS10240	COG3715	PTS system
CCX80_RS10250	COG1482	cell wall glycoprotein biosynthetic process
CCX80_RS10255	COG0778	Nitroreductase
CCX80_RS10265	COG0561	phosphatase activity
CCX80_RS10275	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CCX80_RS10280	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CCX80_RS10295	COG1214	PFAM Peptidase M22, glycoprotease
CCX80_RS10300	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CCX80_RS10310	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CCX80_RS10315	COG0009	L-threonylcarbamoyladenylate synthase
CCX80_RS10320	COG2890	protein-(glutamine-N5) methyltransferase activity
CCX80_RS10325	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CCX80_RS10330	COG1435	thymidine kinase activity
CCX80_RS10335	COG3883	PFAM NLP P60 protein
CCX80_RS10335	COG0791	NLP P60 protein
CCX80_RS10340	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CCX80_RS10345	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CCX80_RS10350	COG3442	glutamine amidotransferase
CCX80_RS10355	COG0531	amino acid
CCX80_RS10365	COG0628	permease
CCX80_RS10370	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CCX80_RS10375	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CCX80_RS10380	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CCX80_RS10390	COG2873	o-acetylhomoserine
CCX80_RS10395	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CCX80_RS10400	COG1854	S-ribosylhomocysteine lyase activity
CCX80_RS10405	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CCX80_RS10410	COG0626	cystathionine gamma-synthase activity
CCX80_RS10415	COG0626	cystathionine gamma-synthase activity
CCX80_RS10420	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
CCX80_RS10425	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CCX80_RS10430	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CCX80_RS10435	COG5002	protein histidine kinase activity
CCX80_RS10440	COG0745	RESPONSE REGULATOR receiver
CCX80_RS10445	COG2337	Toxic component of a toxin-antitoxin (TA) module
CCX80_RS10450	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CCX80_RS10455	COG0736	holo-[acyl-carrier-protein] synthase activity
CCX80_RS10460	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CCX80_RS10465	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CCX80_RS10470	COG1696	Membrane protein involved in D-alanine export
CCX80_RS10475	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CCX80_RS10500	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CCX80_RS10505	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CCX80_RS10510	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CCX80_RS10515	COG0085	RNA polymerase activity
CCX80_RS10555	COG2801	Transposase and inactivated derivatives
CCX80_RS10560	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CCX80_RS10565	COG1573	uracil-dna glycosylase
CCX80_RS10575	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
CCX80_RS10580	COG1733	regulation of RNA biosynthetic process
CCX80_RS10600	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CCX80_RS10630	COG2801	Transposase and inactivated derivatives
CCX80_RS10655	COG1192	Involved in chromosome partitioning
CCX80_RS10665	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CCX80_RS10705	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CCX80_RS10720	COG2409	Drug exporters of the RND superfamily