locus-tag	class	description
C7M45_RS00035	ENOG4105ST3	Transcriptional regulator
C7M45_RS00040	ENOG4105ECB	domain protein
C7M45_RS00040	ENOG4105ECB	domain protein
C7M45_RS00105	ENOG4105EEM	helicase
C7M45_RS00110	ENOG4105CS9	pantothenic acid kinase
C7M45_RS00130	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
C7M45_RS00140	ENOG4107RFS	it plays a direct role in the translocation of protons across the membrane (By similarity)
C7M45_RS00145	ENOG4105WS6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
C7M45_RS00150	ENOG4107ZFM	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
C7M45_RS00155	ENOG4107YZM	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
C7M45_RS00160	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
C7M45_RS00165	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
C7M45_RS00170	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
C7M45_RS00175	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
C7M45_RS00180	ENOG4107X35	defense response to bacterium
C7M45_RS00185	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
C7M45_RS00195	ENOG4105II7	pyrroline-5-carboxylate reductase
C7M45_RS00205	ENOG4105CEN	a g-specific adenine glycosylase
C7M45_RS00210	ENOG4105C02	permease
C7M45_RS00225	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
C7M45_RS00235	ENOG4107R7I	amino acid
C7M45_RS00240	ENOG4108KGH	TRANSCRIPTIONal
C7M45_RS00250	ENOG4108IQI	permease
C7M45_RS00265	ENOG4105D1H	recombination factor protein RarA
C7M45_RS00275	ENOG4105E5W	Transporter
C7M45_RS00285	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
C7M45_RS00290	ENOG4105DGY	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization (By similarity)
C7M45_RS00295	ENOG4105CUB	amino acid
C7M45_RS00300	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
C7M45_RS00305	ENOG4105CHM	Aminotransferase
C7M45_RS00310	ENOG4105C5I	Dehydrogenase
C7M45_RS00370	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
C7M45_RS00375	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
C7M45_RS00380	ENOG4105KEB	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
C7M45_RS00385	ENOG4105C2N	RNA methyltransferase TrmH family group 3
C7M45_RS00410	ENOG4108IQD	Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp (By similarity)
C7M45_RS00415	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
C7M45_RS00420	ENOG4106C1H	Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Activated D-alanyl-Dcp donates its D-alanyl substituent to membrane-associated LTA (By similarity)
C7M45_RS00425	ENOG4108M4D	D-alanyl-lipoteichoic acid biosynthesis protein DltD
C7M45_RS00430	ENOG41082V8	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
C7M45_RS00440	ENOG4108YZM	Toxic component of a toxin-antitoxin (TA) module (By similarity)
C7M45_RS00445	ENOG4108STX	response regulator
C7M45_RS00450	ENOG4105US7	Histidine kinase
C7M45_RS00455	ENOG4105C0H	protease
C7M45_RS00460	ENOG4105SZ6	Thioredoxin
C7M45_RS00465	ENOG4105CVG	Homoserine O-transsuccinylase
C7M45_RS00470	ENOG4105C28	cystathionine
C7M45_RS00475	ENOG4105C28	cystathionine
C7M45_RS00485	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
C7M45_RS00500	ENOG4107QSI	ABC, transporter
C7M45_RS00510	ENOG4105SYT	Methylenetetrahydrofolate reductase
C7M45_RS00515	ENOG4107QYE	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
C7M45_RS00520	ENOG4108IQI	permease
C7M45_RS00525	ENOG4108J5H	Homocysteine s-methyltransferase
C7M45_RS00530	ENOG4106F5Q	Membrane
C7M45_RS00540	ENOG4105C0X	amino acid
C7M45_RS00545	ENOG4105F1K	Glutamine amidotransferase
C7M45_RS00550	ENOG4105DMS	mur ligase
C7M45_RS00555	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
C7M45_RS00560	ENOG4105Z8B	NlpC/P60 family
C7M45_RS00565	ENOG4107104	thymidine kinase
C7M45_RS00570	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
C7M45_RS00575	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
C7M45_RS00580	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
C7M45_RS00585	ENOG4105CTD	carboxy-peptidase
C7M45_RS00590	ENOG4105KRI	phosphocarrier protein (HPr
C7M45_RS00595	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
C7M45_RS00600	ENOG41072GX	Peptidase M22 Glycoprotease
C7M45_RS00615	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
C7M45_RS00620	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
C7M45_RS00630	ENOG4108HCJ	Hydrolase
C7M45_RS00640	ENOG4108DBC	nitroreductase
C7M45_RS00645	ENOG4105DG6	mannose-6-phosphate isomerase
C7M45_RS00655	ENOG4105ETZ	PTS System
C7M45_RS00660	ENOG4105F3R	pts system mannose fructose sorbose family iid
C7M45_RS00675	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
C7M45_RS00680	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
C7M45_RS00700	ENOG4108QY0	Membrane
C7M45_RS00760	ENOG4108Z40	Transcriptional regulator
C7M45_RS00785	ENOG4108WJV	had superfamily (subfamily IIIa) phosphatase
C7M45_RS00790	ENOG4105CQW	ribosome biogenesis GTPase YqeH
C7M45_RS00795	ENOG410812S	Rna-binding protein
C7M45_RS00800	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
C7M45_RS00805	ENOG4108WF2	Metal Dependent Phosphohydrolase
C7M45_RS00815	ENOG4105DXX	methyltransferase
C7M45_RS00820	ENOG4105CDE	UPF0348 protein
C7M45_RS00830	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
C7M45_RS00835	ENOG4105GR3	Histidine kinase
C7M45_RS00840	ENOG410855V	Acylphosphatase
C7M45_RS00845	ENOG4107XQC	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins (By similarity)
C7M45_RS00850	ENOG4108RWN	rrna methyltransferase
C7M45_RS00860	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
C7M45_RS00865	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
C7M45_RS00870	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
C7M45_RS00885	ENOG4107FSS	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
C7M45_RS00905	ENOG4105C98	muts2 protein
C7M45_RS00925	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
C7M45_RS00930	ENOG4105ZAD	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
C7M45_RS00970	ENOG41090SU	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity)
C7M45_RS00975	ENOG4108SQ7	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
C7M45_RS00990	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
C7M45_RS00995	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
C7M45_RS01005	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
C7M45_RS01020	ENOG4108MYP	Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four- carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
C7M45_RS01030	ENOG4105KAF	membrAne
C7M45_RS01230	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
C7M45_RS01340	ENOG4106EHS	UPF0356 protein
C7M45_RS01345	ENOG4108URH	decarboxylase
C7M45_RS01355	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
C7M45_RS01365	ENOG4105M7K	Involved in the transcription termination process (By similarity)
C7M45_RS01370	ENOG4105F8V	Hydrolase, tatD family
C7M45_RS01375	ENOG4105HVR	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity)
C7M45_RS01380	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
C7M45_RS01385	ENOG4105W42	Veg protein
C7M45_RS01395	ENOG4105FDK	ABC transporter
C7M45_RS01400	ENOG4105FAV	ABC, transporter
C7M45_RS01405	ENOG4105DFT	pur operon repressor
C7M45_RS01425	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
C7M45_RS01430	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
C7M45_RS01435	ENOG4105CTB	Polyprenyl synthetase
C7M45_RS01440	ENOG4105DX0	Hemolysin A
C7M45_RS01445	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
C7M45_RS01450	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
C7M45_RS01455	ENOG4105C7N	Xanthine uracil vitamin C permease
C7M45_RS01465	ENOG4108K79	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
C7M45_RS01470	ENOG4105CN9	Peptidase m42 family protein
C7M45_RS01475	ENOG4105CNI	cell division protein FtsW
C7M45_RS01480	ENOG4105WUC	UPF0298 protein
C7M45_RS01485	ENOG4106H78	methyltransferase
C7M45_RS01490	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
C7M45_RS01495	ENOG41063PX	domain protein
C7M45_RS01500	ENOG4105KQC	Competence protein
C7M45_RS01505	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
C7M45_RS01510	ENOG4105TQK	DNA polymerase iii, delta' subunit
C7M45_RS01515	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
C7M45_RS01520	ENOG4105SFS	phosphoesterase RecJ domain protein
C7M45_RS01525	ENOG4105C1J	atp-dependent rna helicase
C7M45_RS01530	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
C7M45_RS01535	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
C7M45_RS01540	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
C7M45_RS01545	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
C7M45_RS01550	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
C7M45_RS01555	ENOG4105CBD	Diacylglycerol kinase
C7M45_RS01560	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
C7M45_RS01565	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
C7M45_RS01570	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
C7M45_RS01575	ENOG4106EMP	CsbD-like
C7M45_RS01580	ENOG4108W15	Protein of unknown function (DUF1456)
C7M45_RS01585	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
C7M45_RS01590	ENOG4105D4A	Cell wall formation (By similarity)
C7M45_RS01595	ENOG4105EEQ	Na H antiporter
C7M45_RS01610	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
C7M45_RS01615	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
C7M45_RS01620	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
C7M45_RS01625	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
C7M45_RS01635	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C7M45_RS01645	ENOG4108HCJ	Hydrolase
C7M45_RS01650	ENOG4108W76	histidinol phosphate phosphatase hisj family
C7M45_RS01660	ENOG4107QZ7	Cellulose synthase catalytic subunit
C7M45_RS01670	ENOG4105BZU	Histidine kinase
C7M45_RS01680	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
C7M45_RS01685	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
C7M45_RS01690	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
C7M45_RS01695	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
C7M45_RS01700	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
C7M45_RS01705	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
C7M45_RS01710	ENOG41083RF	phosphoribosyl-ATP pyrophosphatase
C7M45_RS01715	ENOG4105CIH	Imidazole acetol-phosphate transaminase
C7M45_RS01730	ENOG4108JJB	ABC transporter
C7M45_RS01745	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
C7M45_RS01750	ENOG4105DAP	Nicotinate phosphoribosyltransferase
C7M45_RS01755	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
C7M45_RS01760	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
C7M45_RS01765	ENOG4108KB1	transcriptional regulator, arac family
C7M45_RS01795	ENOG4105K8N	protein family UPF0079, ATPase
C7M45_RS01800	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
C7M45_RS01805	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
C7M45_RS01810	ENOG4105CGK	Exodeoxyribonuclease III
C7M45_RS01815	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
C7M45_RS01835	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
C7M45_RS01840	ENOG4105DZR	Type I site-specific deoxyribonuclease
C7M45_RS01855	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
C7M45_RS01865	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
C7M45_RS01870	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
C7M45_RS01875	ENOG4105E0X	reductase
C7M45_RS01885	ENOG4107VZS	Nicotinamide-nucleotide adenylyltransferase
C7M45_RS01895	ENOG4105C25	Primosomal protein n'
C7M45_RS01900	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
C7M45_RS01905	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
C7M45_RS01910	ENOG4108ZF3	Phosphatase
C7M45_RS01915	ENOG4105D9P	serine threonine protein kinase
C7M45_RS01920	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
C7M45_RS01925	ENOG4105DJV	ribulose-phosphate 3-epimerase
C7M45_RS01930	ENOG4105FJ0	thiamine
C7M45_RS01935	ENOG4105K63	Thioredoxin
C7M45_RS01940	ENOG4105VB9	50S ribosomal protein l28
C7M45_RS01950	ENOG4105DP4	dak2 domain fusion protein ylov
C7M45_RS01965	ENOG4108V6E	Cell division protein mraZ
C7M45_RS01970	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
C7M45_RS01980	ENOG4105CJN	penicillin-binding protein
C7M45_RS01985	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
C7M45_RS01990	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
C7M45_RS01995	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
C7M45_RS02015	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
C7M45_RS02020	ENOG41067XK	integral membrane protein
C7M45_RS02045	ENOG4105K5M	30s ribosomal protein S16
C7M45_RS02055	ENOG4107UWA	esterase
C7M45_RS02060	ENOG4105C5N	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
C7M45_RS02065	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
C7M45_RS02075	ENOG4107Z8R	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
C7M45_RS02080	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
C7M45_RS02085	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
C7M45_RS02090	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
C7M45_RS02095	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
C7M45_RS02100	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
C7M45_RS02105	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
C7M45_RS02135	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
C7M45_RS02140	ENOG4108IJ2	phosphate acetyltransferase
C7M45_RS02150	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
C7M45_RS02155	ENOG4108JQ1	Dehydrogenase
C7M45_RS02165	ENOG4105CDY	transcriptional regulatory protein
C7M45_RS02170	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
C7M45_RS02175	ENOG4105CDH	Citrulline--aspartate ligase
C7M45_RS02180	ENOG4105CH7	arginosuccinase
C7M45_RS02190	ENOG4107QRI	Phosphoketolase
C7M45_RS02205	ENOG4108MIC	Mg-protoporphyrin IX methyl transferase
C7M45_RS02210	ENOG4105F23	Fibronectin-binding protein
C7M45_RS02220	ENOG4105D3R	alkyl hydroperoxide reductase
C7M45_RS02235	ENOG4106N3A	copper homeostasis protein cutc
C7M45_RS02240	ENOG41086FC	50S ribosomal protein l32
C7M45_RS02260	ENOG4105VJV	50s ribosomal protein L35
C7M45_RS02265	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
C7M45_RS02270	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
C7M45_RS02275	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
C7M45_RS02280	ENOG4108KGH	TRANSCRIPTIONal
C7M45_RS02285	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
C7M45_RS02295	ENOG4105HTX	biosynthesis protein
C7M45_RS02300	ENOG4107YJ4	chain length determinant protein
C7M45_RS02305	ENOG4105D3Q	Sugar transferase
C7M45_RS02315	ENOG4105KPE	licD family
C7M45_RS02320	ENOG4107YSK	Glycerol-3-phosphate cytidylyltransferase
C7M45_RS02350	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
C7M45_RS02360	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
C7M45_RS02365	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
C7M45_RS02410	ENOG4105EDQ	levansucrase EC 2.4.1.10
C7M45_RS02415	ENOG4105EDQ	levansucrase EC 2.4.1.10
C7M45_RS02430	ENOG4105D3Q	Sugar transferase
C7M45_RS02450	ENOG4105D5D	udp-galactopyranose mutase
C7M45_RS02455	ENOG4105CKK	Glycosyl transferase, family 2
C7M45_RS02475	ENOG4108RJ9	Glycosyl transferase, family 2
C7M45_RS02485	ENOG4105NQC	Flavodoxin
C7M45_RS02490	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
C7M45_RS02495	ENOG4105TMB	Formate nitrite transporter
C7M45_RS02500	ENOG4105C83	adenylosuccinate lyase
C7M45_RS02510	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
C7M45_RS02530	ENOG4105DVT	helicase
C7M45_RS02545	ENOG4105C5S	asparaginyl-tRNA synthetase
C7M45_RS02560	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
C7M45_RS02565	ENOG4105CHM	Aminotransferase
C7M45_RS02575	ENOG4105VND	Ribonuclease
C7M45_RS02585	ENOG4105C34	Pseudouridine synthase
C7M45_RS02590	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
C7M45_RS02595	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
C7M45_RS02600	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
C7M45_RS02615	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
C7M45_RS02620	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
C7M45_RS02625	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
C7M45_RS02630	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
C7M45_RS02635	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
C7M45_RS02640	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
C7M45_RS02650	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
C7M45_RS02655	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
C7M45_RS02660	ENOG4105CHV	Transcription elongation factor NusA
C7M45_RS02665	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
C7M45_RS02675	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
C7M45_RS02680	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
C7M45_RS02685	ENOG4105CHM	Aminotransferase
C7M45_RS02695	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
C7M45_RS02700	ENOG4105DTN	riboflavin biosynthesis protein ribF
C7M45_RS02705	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
C7M45_RS02710	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
C7M45_RS02715	ENOG4105CFG	Acts as a chaperone (By similarity)
C7M45_RS02720	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
C7M45_RS02725	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
C7M45_RS02730	ENOG4105WBI	UPF0223 protein
C7M45_RS02735	ENOG4105ECY	inositol monophosphatase
C7M45_RS02740	ENOG4105CI3	gtp-binding protein typa
C7M45_RS02760	ENOG4105KPY	Small multidrug resistance protein
C7M45_RS02770	ENOG4105FR1	rard protein
C7M45_RS02775	ENOG4107TCE	N-acetyltransferase
C7M45_RS02815	ENOG4105K46	50S ribosomal protein l27
C7M45_RS02820	ENOG4105DC7	peptidase M24
C7M45_RS02830	ENOG4107R8B	5'-nucleotidase
C7M45_RS02835	ENOG4105MMD	transcriptional regulator
C7M45_RS02845	ENOG4105CM2	brancheD-chain amino acid aminotransferase
C7M45_RS02850	ENOG4105C5I	Dehydrogenase
C7M45_RS02860	ENOG4105CNT	hydrolase family 2
C7M45_RS02865	ENOG4105CPC	Aldo Keto reductase
C7M45_RS02870	ENOG4107RBJ	symporter
C7M45_RS02875	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
C7M45_RS02885	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
C7M45_RS02890	ENOG4105CUT	histidyl-tRNA synthetase
C7M45_RS02895	ENOG4105C9M	aspartyl-trna synthetase
C7M45_RS02900	ENOG4107AYK	membrAne
C7M45_RS02905	ENOG4105C85	amino acid
C7M45_RS02910	ENOG4105G9B	Transcriptional regulator
C7M45_RS02915	ENOG4105CSH	Transporter
C7M45_RS02920	ENOG4105VCC	30S ribosomal protein S21
C7M45_RS02925	ENOG4105KTH	gatB Yqey
C7M45_RS02930	ENOG4105QNR	S1 RNA binding domain protein
C7M45_RS02935	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
C7M45_RS02945	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
C7M45_RS02950	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
C7M45_RS02955	ENOG4105FE9	pseudouridine synthase
C7M45_RS02970	ENOG4105CAT	Cytidine monophosphate kinase
C7M45_RS02975	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
C7M45_RS02980	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
C7M45_RS02985	ENOG4105K70	DNA-binding protein
C7M45_RS02995	ENOG4105D7W	serine acetyltransferase
C7M45_RS03000	ENOG4105C28	cystathionine
C7M45_RS03005	ENOG4105C6T	cysteine synthase
C7M45_RS03015	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
C7M45_RS03035	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
C7M45_RS03045	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
C7M45_RS03050	ENOG4105C5H	ABC transporter
C7M45_RS03055	ENOG4105C79	DNA protecting protein DprA
C7M45_RS03085	ENOG4105F3R	pts system mannose fructose sorbose family iid
C7M45_RS03095	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
C7M45_RS03100	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
C7M45_RS03110	ENOG4105CHR	reductase
C7M45_RS03120	ENOG4105C28	cystathionine
C7M45_RS03125	ENOG4105EAB	amino acid AbC transporter
C7M45_RS03130	ENOG4105E5Q	amino acid AbC transporter
C7M45_RS03135	ENOG4105CDA	abc transporter atp-binding protein
C7M45_RS03140	ENOG4108JQ1	Dehydrogenase
C7M45_RS03145	ENOG4105CHM	Aminotransferase
C7M45_RS03155	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
C7M45_RS03165	ENOG4105K59	histidine triad (HIT) protein
C7M45_RS03180	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
C7M45_RS03255	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
C7M45_RS03265	ENOG4105C75	arginyL-tRNA synthetase
C7M45_RS03270	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
C7M45_RS03275	ENOG4105BZ4	penicillin-binding protein
C7M45_RS03280	ENOG4105WZB	UPF0342 protein
C7M45_RS03290	ENOG4105CXT	aspartate transcarbamylase
C7M45_RS03295	ENOG4105CD3	dihydroorotase
C7M45_RS03300	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
C7M45_RS03305	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
C7M45_RS03310	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
C7M45_RS03315	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
C7M45_RS03320	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
C7M45_RS03325	ENOG4105VXM	UPF0154 protein
C7M45_RS03330	ENOG4105F6E	Acyl-transferase
C7M45_RS03335	ENOG41060K3	Methyltransferase
C7M45_RS03340	ENOG4105VC4	domain protein
C7M45_RS03345	ENOG4105CE9	30S ribosomal protein S2
C7M45_RS03350	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
C7M45_RS03355	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
C7M45_RS03360	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
C7M45_RS03370	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
C7M45_RS03375	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
C7M45_RS03380	ENOG4105D9R	oxidoreductase
C7M45_RS03385	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
C7M45_RS03400	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
C7M45_RS03405	ENOG4107TVK	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
C7M45_RS03415	ENOG4105C5H	ABC transporter
C7M45_RS03420	ENOG4105F99	Hydroxymethylglutaryl-CoA synthase
C7M45_RS03435	ENOG4105VUC	UPF0237 protein
C7M45_RS03440	ENOG4105CAG	UPF0210 protein
C7M45_RS03450	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
C7M45_RS03465	ENOG4108I0Q	anthranilate phosphoribosyltransferase
C7M45_RS03470	ENOG4105DK0	Indole-3-glycerol phosphate synthase
C7M45_RS03475	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
C7M45_RS03480	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
C7M45_RS03485	ENOG4105CRQ	synthase (Component I)
C7M45_RS03490	ENOG4105DDQ	anthranilate synthase
C7M45_RS03495	ENOG4105CV1	Transketolase (EC 2.2.1.1)
C7M45_RS03505	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
C7M45_RS03510	ENOG4105D49	3-dehydroquinate synthase
C7M45_RS03515	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
C7M45_RS03520	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
C7M45_RS03525	ENOG4105EVN	Prephenate dehydrogenase
C7M45_RS03530	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
C7M45_RS03540	ENOG4105FF2	Type I DHQase
C7M45_RS03545	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
C7M45_RS03550	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
C7M45_RS03555	ENOG4105D06	uba thif-type nad fad binding protein
C7M45_RS03560	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
C7M45_RS03565	ENOG4105CXY	transporter
C7M45_RS03575	ENOG4105CHR	reductase
C7M45_RS03600	ENOG4105EYF	MMPL domain protein
C7M45_RS03605	ENOG4105ENE	Histidine kinase
C7M45_RS03610	ENOG4108VB1	regulatoR
C7M45_RS03645	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
C7M45_RS03680	ENOG4105F9F	transposase
C7M45_RS03765	ENOG41089N3	Inherit from COG: cobyrinic Acid a,c-diamide synthase
C7M45_RS03790	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
C7M45_RS03875	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
C7M45_RS03880	ENOG4105ECB	domain protein
C7M45_RS03885	ENOG4105KA3	membrAne
C7M45_RS03890	ENOG4105CIS	alcohol dehydrogenase
C7M45_RS03895	ENOG4105DC8	reductase
C7M45_RS03900	ENOG4105K56	Transcriptional regulator
C7M45_RS03930	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
C7M45_RS03965	ENOG4105DZR	Type I site-specific deoxyribonuclease
C7M45_RS04025	ENOG4105U0F	oligosaccharide H symporter, major facilitator superfamily (MFS)
C7M45_RS04030	ENOG4107R3K	hydrolase
C7M45_RS04040	ENOG4105ETE	Transcriptional regulator (LacI family
C7M45_RS04120	ENOG4105CBK	multidrug resistance protein
C7M45_RS04195	ENOG4105F9F	transposase
C7M45_RS04205	ENOG4105RV9	Transcriptional regulator
C7M45_RS04215	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
C7M45_RS04225	ENOG4105JAB	phenazine biosynthesis protein, phzf family
C7M45_RS04235	ENOG4107UIE	peptidase
C7M45_RS04240	ENOG4105ETU	transcriptional activator (TenA
C7M45_RS04260	ENOG4107Y70	Heat shock protein
C7M45_RS04265	ENOG4105C7K	acetolactate synthase
C7M45_RS04280	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
C7M45_RS04320	ENOG4107QJZ	Glycosyl transferase, family 2
C7M45_RS04340	ENOG4105E1F	short-chain dehydrogenase reductase
C7M45_RS04345	ENOG4105C5I	Dehydrogenase
C7M45_RS04350	ENOG4108NIW	Leucine export protein LeuE
C7M45_RS04355	ENOG4108UIN	ybak prolyl-trna synthetase associated region
C7M45_RS04360	ENOG4105VUF	Transcriptional regulator
C7M45_RS04380	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
C7M45_RS04385	ENOG4108T3F	Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes
C7M45_RS04390	ENOG4108KGH	TRANSCRIPTIONal
C7M45_RS04410	ENOG4105BZU	Histidine kinase
C7M45_RS04415	ENOG4105EFI	regulatoR
C7M45_RS04425	ENOG4107FQX	Alpha-acetolactate decarboxylase
C7M45_RS04430	ENOG4105DSE	periplasmic solute binding protein
C7M45_RS04435	ENOG4105CC5	ABC transporter
C7M45_RS04440	ENOG4105DIK	(ABC) transporter
C7M45_RS04445	ENOG4105X1N	Glycosyl transferase family 8
C7M45_RS04455	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
C7M45_RS04460	ENOG4105DC8	reductase
C7M45_RS04465	ENOG4105K56	Transcriptional regulator
C7M45_RS04485	ENOG4105CS2	ec 3.2.1.21
C7M45_RS04505	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
C7M45_RS04515	ENOG4105CHR	reductase
C7M45_RS04535	ENOG4105CK1	PTS System
C7M45_RS04545	ENOG4105VCP	PTS System
C7M45_RS04550	ENOG4105EMD	TRANSCRIPTIONal
C7M45_RS04560	ENOG4105CS2	ec 3.2.1.21
C7M45_RS04570	ENOG4105EU2	peptidase U61 LD-carboxypeptidase A
C7M45_RS04575	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
C7M45_RS04580	ENOG4105C6Z	Gluconate
C7M45_RS04585	ENOG4105CHR	reductase
C7M45_RS04590	ENOG4105CHM	Aminotransferase
C7M45_RS04600	ENOG4108Z0Z	intracellular protease Pfpi family
C7M45_RS04615	ENOG4105PUK	Membrane
C7M45_RS04620	ENOG4108RG0	uracil-dna glycosylase
C7M45_RS04625	ENOG4108JJB	ABC transporter
C7M45_RS04640	ENOG41079KZ	Major Facilitator Superfamily
C7M45_RS04650	ENOG4105E1F	short-chain dehydrogenase reductase
C7M45_RS04665	ENOG4105CND	Glycosyl transferase, family 2
C7M45_RS04695	ENOG4105ETE	Transcriptional regulator (LacI family
C7M45_RS04715	ENOG4105CS2	ec 3.2.1.21
C7M45_RS04725	ENOG4105CID	antiterminator
C7M45_RS04730	ENOG4105CG3	alpha amylase, catalytic region
C7M45_RS04740	ENOG4105CG3	alpha amylase, catalytic region
C7M45_RS04750	ENOG4107URF	beta-phospho-glucomutase
C7M45_RS04765	ENOG4105FKQ	transcriptional regulator
C7M45_RS04790	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
C7M45_RS04795	ENOG4105CKN	UDP-glucose-hexose-1-phosphate uridylyltransferase
C7M45_RS04800	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
C7M45_RS04805	ENOG4105DME	alpha-galactosidase
C7M45_RS04815	ENOG4107RBJ	symporter
C7M45_RS04820	ENOG4108ZMI	UPF0477 protein
C7M45_RS04840	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
C7M45_RS04850	ENOG4107QNK	)-transporter
C7M45_RS04860	ENOG4107BMA	Transglycosylase associated protein
C7M45_RS04870	ENOG4105VBF	alkaline shock protein
C7M45_RS04885	ENOG4107BMA	Transglycosylase associated protein
C7M45_RS04900	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
C7M45_RS04905	ENOG4107R0P	L-ribulose-5-phosphate 4-epimerase
C7M45_RS04915	ENOG4107QNK	)-transporter
C7M45_RS04920	ENOG4105CAC	Catalyzes the conversion of L-arabinose to L-ribulose (By similarity)
C7M45_RS04925	ENOG4105CMD	Transcriptional regulator, GntR family
C7M45_RS04940	ENOG4105W1Y	Transcriptional regulator
C7M45_RS04980	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
C7M45_RS04985	ENOG4105CPC	Aldo Keto reductase
C7M45_RS05005	ENOG4105C5Q	Transcriptional regulator
C7M45_RS05015	ENOG4105C19	ABC transporter
C7M45_RS05020	ENOG4105EWM	Histidine kinase
C7M45_RS05025	ENOG4105CJZ	response regulator
C7M45_RS05030	ENOG4108V4B	ThiJ pfpI
C7M45_RS05050	ENOG4105ETE	Transcriptional regulator (LacI family
C7M45_RS05060	ENOG4107QNK	)-transporter
C7M45_RS05070	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
C7M45_RS05080	ENOG4108R6K	riboflavin synthase, subunit alpha
C7M45_RS05085	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
C7M45_RS05100	ENOG4105BZ8	glutamate synthase
C7M45_RS05110	ENOG4105KWG	Pfam:DUF1696
C7M45_RS05120	ENOG4105EYF	MMPL domain protein
C7M45_RS05135	ENOG4105I2S	Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity)
C7M45_RS05140	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
C7M45_RS05145	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
C7M45_RS05160	ENOG4105DC8	reductase
C7M45_RS05170	ENOG4105FDK	ABC transporter
C7M45_RS05185	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
C7M45_RS05190	ENOG4105C2X	Arabinose 5-phosphate isomerase
C7M45_RS05205	ENOG4105DU0	nucleoside hydrolase
C7M45_RS05215	ENOG4105ETE	Transcriptional regulator (LacI family
C7M45_RS05225	ENOG4105E66	phosphoriboisomerase A
C7M45_RS05245	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
C7M45_RS05250	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
C7M45_RS05255	ENOG4107QID	Threonine synthase
C7M45_RS05260	ENOG4105D6E	homoserine dehydrogenase
C7M45_RS05265	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
C7M45_RS05270	ENOG4105CFH	Aspartokinase
C7M45_RS05280	ENOG4107RB3	L-asparaginase
C7M45_RS05285	ENOG4108SAY	Involved in DNA repair and RecF pathway recombination (By similarity)
C7M45_RS05290	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
C7M45_RS05300	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
C7M45_RS05305	ENOG4105C9A	Phoh family
C7M45_RS05310	ENOG4105BZU	Histidine kinase
C7M45_RS05315	ENOG4105CA9	Pyruvate kinase
C7M45_RS05320	ENOG4105C0B	DNA polymerase III (alpha subunit)
C7M45_RS05330	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
C7M45_RS05335	ENOG4105EGD	dinuclear metal center protein, YbgI family
C7M45_RS05355	ENOG4108JJB	ABC transporter
C7M45_RS05365	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
C7M45_RS05370	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
C7M45_RS05375	ENOG4106E6V	UPF0346 protein
C7M45_RS05385	ENOG41090WU	lipolytic protein G-D-S-L family
C7M45_RS05395	ENOG4105DU0	nucleoside hydrolase
C7M45_RS05400	ENOG4108RCR	degv family
C7M45_RS05410	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
C7M45_RS05425	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
C7M45_RS05430	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
C7M45_RS05435	ENOG4105E4F	Isochorismate synthase
C7M45_RS05440	ENOG4105DWF	phosphomethylpyrimidine kinase
C7M45_RS05450	ENOG4108JYZ	YitT family
C7M45_RS05455	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
C7M45_RS05475	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
C7M45_RS05485	ENOG4107QN2	dihydrolipoyl dehydrogenase
C7M45_RS05490	ENOG4105C7S	Dehydrogenase
C7M45_RS05495	ENOG4105CPP	Dehydrogenase, E1 component
C7M45_RS05505	ENOG4105DF9	Lipoate-protein, ligase
C7M45_RS05515	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
C7M45_RS05535	ENOG4106D4I	domain protein
C7M45_RS05540	ENOG4107VRP	DNA repair exonuclease
C7M45_RS05545	ENOG4105DC1	bifunctional purine biosynthesis protein purh
C7M45_RS05550	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
C7M45_RS05555	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
C7M45_RS05565	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
C7M45_RS05580	ENOG4105C8V	SAICAR synthetase
C7M45_RS05585	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
C7M45_RS05590	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
C7M45_RS05595	ENOG4105C5F	glutamine synthetase
C7M45_RS05600	ENOG4105KV4	Transcriptional regulator
C7M45_RS05610	ENOG4108Z6X	(sortase) family
C7M45_RS05615	ENOG4105C2M	dna polymerase I
C7M45_RS05620	ENOG4105D7K	pfkb domain protein
C7M45_RS05635	ENOG4105DFU	Cell wall formation (By similarity)
C7M45_RS05645	ENOG4108VDD	TRNA binding domain protein
C7M45_RS05650	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
C7M45_RS05660	ENOG4108YZ4	nudix hydrolase
C7M45_RS05665	ENOG4105VEQ	Cold shock protein
C7M45_RS05675	ENOG4105CKU	formyltetrahydrofolate synthetase
C7M45_RS05680	ENOG4105C12	Phosphoribosylglycinamide synthetase
C7M45_RS05685	ENOG4105CPC	Aldo Keto reductase
C7M45_RS05695	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
C7M45_RS05700	ENOG4105C7H	Helicase, RecD TraA family
C7M45_RS05715	ENOG4105DIH	basic membrane
C7M45_RS05720	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
C7M45_RS05735	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
C7M45_RS05740	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
C7M45_RS05745	ENOG4105DZP	Membrane-associated zinc metalloprotease
C7M45_RS05750	ENOG4105KNE	Phosphatidate cytidylyltransferase
C7M45_RS05755	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
C7M45_RS05760	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
C7M45_RS05765	ENOG4105CPN	adenine deaminase
C7M45_RS05775	ENOG4105CJW	magnesium transporter
C7M45_RS05780	ENOG4105EMS	pseudouridine synthase
C7M45_RS05785	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
C7M45_RS05815	ENOG4105EVI	UPF0374 protein
C7M45_RS05820	ENOG410902V	Modulates RecA activity (By similarity)
C7M45_RS05825	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
C7M45_RS05830	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
C7M45_RS05835	ENOG4105CH2	amidohydrolase
C7M45_RS05840	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
C7M45_RS05850	ENOG4105FGM	Fructosamine kinase
C7M45_RS05860	ENOG4105DQR	SNARE associated Golgi
C7M45_RS05865	ENOG4105C85	amino acid
C7M45_RS05870	ENOG4105C22	threonyL-tRNA synthetase
C7M45_RS05875	ENOG4105CNU	cell division protein FtsK
C7M45_RS05885	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
C7M45_RS05895	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
C7M45_RS05900	ENOG4108HW3	(ABC) transporter
C7M45_RS05910	ENOG4105XWG	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation (By similarity)
C7M45_RS05915	ENOG4108UKS	UPF0398 protein
C7M45_RS05925	ENOG4108UI2	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation (By similarity)
C7M45_RS05935	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
C7M45_RS05940	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
C7M45_RS05945	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
C7M45_RS05950	ENOG4106EMP	CsbD-like
C7M45_RS05960	ENOG41069HH	4-oxalocrotonate tautomerase
C7M45_RS05965	ENOG4107AYK	membrAne
C7M45_RS05970	ENOG4105D0M	Protease HtpX homolog
C7M45_RS05975	ENOG4108V0P	LemA family
C7M45_RS05995	ENOG4105C8T	Leucyl-tRNA synthetase
C7M45_RS06000	ENOG410841Q	phosphoesterase PA-phosphatase related protein
C7M45_RS06010	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
C7M45_RS06020	ENOG4105E66	phosphoriboisomerase A
C7M45_RS06025	ENOG4105CDA	abc transporter atp-binding protein
C7M45_RS06030	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
C7M45_RS06070	ENOG4107WD8	ABC transporter, permease
C7M45_RS06075	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
C7M45_RS06080	ENOG4105ZMH	deoxynucleoside kinase
C7M45_RS06085	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
C7M45_RS06090	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
C7M45_RS06095	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
C7M45_RS06105	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
C7M45_RS06115	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
C7M45_RS06120	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
C7M45_RS06130	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
C7M45_RS06145	ENOG4105ETE	Transcriptional regulator (LacI family
C7M45_RS06150	ENOG4105CPQ	Dehydrogenase
C7M45_RS06165	ENOG4105C3M	thioredoxin reductase
C7M45_RS06170	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
C7M45_RS06175	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
C7M45_RS06180	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
C7M45_RS06185	ENOG41086DT	Membrane protein of unknown function
C7M45_RS06195	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
C7M45_RS06200	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
C7M45_RS06205	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
C7M45_RS06210	ENOG4105E2Z	phosphate ABC transporter (Permease
C7M45_RS06215	ENOG4105C8U	phosphate abc transporter
C7M45_RS06220	ENOG4105CVA	phosphate
C7M45_RS06225	ENOG4105BZU	Histidine kinase
C7M45_RS06230	ENOG4105CVA	phosphate
C7M45_RS06235	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
C7M45_RS06240	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
C7M45_RS06245	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
C7M45_RS06270	ENOG4105EAB	amino acid AbC transporter
C7M45_RS06280	ENOG4105E5Q	amino acid AbC transporter
C7M45_RS06290	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
C7M45_RS06295	ENOG4105DFF	Rod shape-determining protein mreb
C7M45_RS06300	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
C7M45_RS06315	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
C7M45_RS06325	ENOG4105C4R	Atp-dependent dna helicase
C7M45_RS06330	ENOG4108MK9	spermidine N(1)-acetyltransferase
C7M45_RS06335	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
C7M45_RS06340	ENOG4108JJ8	(ABC) transporter
C7M45_RS06345	ENOG4108JJ9	ABC, transporter
C7M45_RS06350	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
C7M45_RS06355	ENOG4105C4M	(Ubiquinol oxidase) subunit I
C7M45_RS06360	ENOG4105VPH	UPF0473 protein
C7M45_RS06365	ENOG4108Z08	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
C7M45_RS06370	ENOG4105VBH	UPF0297 protein
C7M45_RS06375	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
C7M45_RS06380	ENOG4108JPW	Aminotransferase
C7M45_RS06385	ENOG4105CUB	amino acid
C7M45_RS06395	ENOG4105CMG	Carbohydrate kinase
C7M45_RS06405	ENOG4106KNT	transcriptional regulator
C7M45_RS06410	ENOG4107FQX	Alpha-acetolactate decarboxylase
C7M45_RS06415	ENOG4108UZ3	Transporter
C7M45_RS06430	ENOG4105EXC	Acyl-transferase
C7M45_RS06435	ENOG4105ETE	Transcriptional regulator (LacI family
C7M45_RS06440	ENOG4105DC7	peptidase M24
C7M45_RS06455	ENOG410667J	hydrolase
C7M45_RS06460	ENOG410906U	SprT-like
C7M45_RS06465	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
C7M45_RS06470	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
C7M45_RS06475	ENOG4105CB5	ATP-dependent DNA helicase recG
C7M45_RS06510	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
C7M45_RS06520	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
C7M45_RS06525	ENOG4105FDU	atp-dependent rna helicase
C7M45_RS06530	ENOG4105EE0	oxidoreductase
C7M45_RS06540	ENOG4105C88	aminopeptidase
C7M45_RS06550	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
C7M45_RS06555	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
C7M45_RS06560	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
C7M45_RS06565	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
C7M45_RS06575	ENOG41080Y5	BioY family
C7M45_RS06590	ENOG4108Z1Y	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling (By similarity)
C7M45_RS06600	ENOG4105DCI	Phosphohydrolase
C7M45_RS06605	ENOG4107414	GntR family transcriptional regulator
C7M45_RS06610	ENOG4105CG3	alpha amylase, catalytic region
C7M45_RS06615	ENOG4105C5Y	PTS System
C7M45_RS06620	ENOG4105C5Y	PTS System
C7M45_RS06625	ENOG4105GYP	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity)
C7M45_RS06635	ENOG4105CD8	aminopeptidase N
C7M45_RS06645	ENOG4105D7K	pfkb domain protein
C7M45_RS06665	ENOG4108M60	Transcriptional regulator
C7M45_RS06670	ENOG4107SUZ	Sodium/hydrogen exchanger family
C7M45_RS06675	ENOG4108WQ8	UPF0637 protein
C7M45_RS06695	ENOG4105G5W	regulator Fur family
C7M45_RS06715	ENOG4105C26	Dehydrogenase
C7M45_RS06720	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
C7M45_RS06725	ENOG4105DWF	phosphomethylpyrimidine kinase
C7M45_RS06730	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
C7M45_RS06735	ENOG4108IV0	ABC, transporter
C7M45_RS06740	ENOG4105C0Z	ABC transporter
C7M45_RS06745	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
C7M45_RS06750	ENOG4105C32	Amino acid ABC transporter (Permease)
C7M45_RS06755	ENOG4105CP9	extracellular ligand-binding receptor
C7M45_RS06790	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
C7M45_RS06795	ENOG4105CSC	Glucose uptake protein
C7M45_RS06835	ENOG4106855	Competence protein
C7M45_RS06850	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
C7M45_RS06855	ENOG4108UK2	deaminase
C7M45_RS06860	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
C7M45_RS06865	ENOG4105W5Q	DNA repair protein (RadC
C7M45_RS06870	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
C7M45_RS06880	ENOG4105C1J	atp-dependent rna helicase
C7M45_RS06890	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
C7M45_RS06895	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
C7M45_RS06900	ENOG4105NRA	50s ribosomal protein l31 type b
C7M45_RS06905	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
C7M45_RS06910	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
C7M45_RS06915	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
C7M45_RS06925	ENOG4105C5I	Dehydrogenase
C7M45_RS06950	ENOG4105EAD	ABC transporter
C7M45_RS06955	ENOG4105CDA	abc transporter atp-binding protein
C7M45_RS06960	ENOG4105EAD	ABC transporter
C7M45_RS06965	ENOG4105DIH	basic membrane
C7M45_RS06995	ENOG4105D01	(LipO)protein
C7M45_RS07005	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
C7M45_RS07010	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
C7M45_RS07015	ENOG4108UMI	ABC transporter, permease
C7M45_RS07020	ENOG4105FDP	GntR family transcriptional regulator
C7M45_RS07025	ENOG4105CE4	GlcNAc 6-P deacetylase
C7M45_RS07075	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
C7M45_RS07080	ENOG4105C7N	Xanthine uracil vitamin C permease
C7M45_RS07090	ENOG4107QT5	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
C7M45_RS07095	ENOG4105CDY	transcriptional regulatory protein
C7M45_RS07100	ENOG4108R99	pseudouridine synthase
C7M45_RS07120	ENOG4105CRK	lysyL-tRNA synthetase
C7M45_RS07125	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
C7M45_RS07130	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
C7M45_RS07135	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
C7M45_RS07140	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
C7M45_RS07150	ENOG41082I2	s4 domain protein
C7M45_RS07155	ENOG4108JA2	transcriptioN-repair coupling factor
C7M45_RS07160	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
C7M45_RS07170	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
C7M45_RS07175	ENOG4105CIE	May be required for sporulation (By similarity)
C7M45_RS07180	ENOG4105CHW	UPF0052 protein
C7M45_RS07185	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
C7M45_RS07190	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
C7M45_RS07195	ENOG4105E0M	Sulfatase
C7M45_RS07210	ENOG4105W2C	Glycosyl transferase
C7M45_RS07215	ENOG4105BZF	Glycosyl transferase (Group 1
C7M45_RS07220	ENOG4105BZ1	(ABC) transporter
C7M45_RS07225	ENOG4105BZ1	(ABC) transporter
C7M45_RS07240	ENOG4105CVJ	phosphoglycerate mutase
C7M45_RS07265	ENOG4105VIE	preprotein translocase, subunit YajC
C7M45_RS07270	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
C7M45_RS07275	ENOG4105CZM	Major Facilitator
C7M45_RS07280	ENOG4105CDA	abc transporter atp-binding protein
C7M45_RS07285	ENOG4105C5I	Dehydrogenase
C7M45_RS07295	ENOG4105CDA	abc transporter atp-binding protein
C7M45_RS07345	ENOG4108IUX	(ABC) transporter
C7M45_RS07365	ENOG4108IJ7	Glycine betaine
C7M45_RS07375	ENOG4107QYV	phosphohexose isomerase
C7M45_RS07380	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
C7M45_RS07395	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
C7M45_RS07405	ENOG4105C3G	gtp-binding protein
C7M45_RS07410	ENOG4105VDK	protein, conserved in bacteria
C7M45_RS07415	ENOG4105FA0	parb-like partition protein
C7M45_RS07420	ENOG4107QJE	Chromosome Partitioning Protein
C7M45_RS07425	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
C7M45_RS07430	ENOG4105DU0	nucleoside hydrolase
C7M45_RS07445	ENOG41066UM	arsR family transcriptional regulator
C7M45_RS07455	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
C7M45_RS07465	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
C7M45_RS07490	ENOG4108KGH	TRANSCRIPTIONal
C7M45_RS07495	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
C7M45_RS07505	ENOG41082BM	Transcriptional regulator, arsr family
C7M45_RS07510	ENOG4107RF6	penicillin-binding protein
C7M45_RS07535	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
C7M45_RS07540	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
C7M45_RS07560	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
C7M45_RS07565	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
C7M45_RS07570	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
C7M45_RS07575	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
C7M45_RS07580	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
C7M45_RS07585	ENOG4105CHR	reductase
C7M45_RS07590	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
C7M45_RS07600	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
C7M45_RS07615	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
C7M45_RS07625	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
C7M45_RS07630	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
C7M45_RS07635	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
C7M45_RS07645	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
C7M45_RS07650	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
C7M45_RS07665	ENOG4105CAY	ferredoxin--nadp reductase
C7M45_RS07675	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
C7M45_RS07680	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
C7M45_RS07685	ENOG4105ZMH	deoxynucleoside kinase
C7M45_RS07700	ENOG4105EVU	fructokinase
C7M45_RS07710	ENOG4105C5Y	PTS System
C7M45_RS07730	ENOG4105CMR	udp-glucose 4-epimerase
C7M45_RS07745	ENOG4105FA2	dna polymerase iii
C7M45_RS07750	ENOG4105X0R	protein from nitrogen regulatory protein P-II
C7M45_RS07755	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
C7M45_RS07765	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
C7M45_RS07770	ENOG4105C6E	dna polymerase iii
C7M45_RS07785	ENOG4108Z6B	deaminase
C7M45_RS07790	ENOG4107Y49	methyltransferase
C7M45_RS07795	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
C7M45_RS07800	ENOG4108VZM	50s ribosomal protein L10
C7M45_RS07805	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
C7M45_RS07810	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
C7M45_RS07815	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
C7M45_RS07835	ENOG4105CPF	Cell wall formation (By similarity)
C7M45_RS07855	ENOG4105DFF	Rod shape-determining protein mreb
C7M45_RS07870	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
C7M45_RS07885	ENOG4105MTF	NrdI protein
C7M45_RS07890	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
C7M45_RS07895	ENOG4105WAZ	(Glutaredoxin-like protein) NrdH
C7M45_RS07900	ENOG4105C37	(CBS) domain
C7M45_RS07905	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
C7M45_RS07920	ENOG41081UC	Inherit from COG: Competence protein
C7M45_RS07930	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
C7M45_RS07940	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
C7M45_RS07950	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
C7M45_RS07955	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
C7M45_RS07960	ENOG4105CP7	Triose-phosphate isomerase
C7M45_RS07990	ENOG4108UJD	30S ribosomal protein S9
C7M45_RS07995	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
C7M45_RS08005	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
C7M45_RS08010	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
C7M45_RS08015	ENOG4108JJB	ABC transporter
C7M45_RS08020	ENOG4108JJB	ABC transporter
C7M45_RS08030	ENOG4105EAH	synthase
C7M45_RS08035	ENOG4108ZT0	50S ribosomal protein l17
C7M45_RS08040	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
C7M45_RS08045	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
C7M45_RS08050	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
C7M45_RS08060	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
C7M45_RS08065	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
C7M45_RS08070	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
C7M45_RS08075	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
C7M45_RS08085	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
C7M45_RS08090	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
C7M45_RS08095	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
C7M45_RS08100	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
C7M45_RS08105	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
C7M45_RS08110	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
C7M45_RS08115	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
C7M45_RS08120	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
C7M45_RS08125	ENOG41082SA	50s ribosomal protein l29
C7M45_RS08130	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
C7M45_RS08135	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
C7M45_RS08140	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
C7M45_RS08145	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
C7M45_RS08150	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
C7M45_RS08155	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
C7M45_RS08160	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
C7M45_RS08165	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
C7M45_RS08170	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
C7M45_RS08175	ENOG4107RUE	extracellular solute-binding protein family 1
C7M45_RS08180	ENOG4105D38	putrescine abc transporter
C7M45_RS08185	ENOG4105NRK	Binding-protein-dependent transport systems, inner membrane component
C7M45_RS08190	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
C7M45_RS08195	ENOG4105DJ2	Major Facilitator Superfamily
C7M45_RS08200	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
C7M45_RS08205	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
C7M45_RS08210	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
C7M45_RS08220	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
C7M45_RS08225	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
C7M45_RS08230	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
C7M45_RS08235	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
C7M45_RS08335	ENOG4105C8N	cysteinyl-tRNA synthetase
C7M45_RS08340	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
C7M45_RS08345	ENOG4105MKU	Transcriptional regulator
C7M45_RS08360	ENOG4107Z0P	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
C7M45_RS08370	ENOG4105E66	phosphoriboisomerase A
C7M45_RS08375	ENOG4108IJ0	Aspartate ammonia-lyase
C7M45_RS08405	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
C7M45_RS08410	ENOG4108EKI	Dehydrogenase
C7M45_RS08415	ENOG4105CHR	reductase
C7M45_RS08425	ENOG4105DWF	phosphomethylpyrimidine kinase
C7M45_RS08430	ENOG4105X71	Membrane
C7M45_RS08440	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
C7M45_RS08445	ENOG4105CDA	abc transporter atp-binding protein
C7M45_RS08475	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
C7M45_RS08485	ENOG4105CMG	Carbohydrate kinase
C7M45_RS08490	ENOG4105C93	Xylose Isomerase
C7M45_RS08505	ENOG4108UT2	hemolysin iii
C7M45_RS08510	ENOG4105EPR	degv family
C7M45_RS08515	ENOG4106A8V	Protein CrcB homolog
C7M45_RS08520	ENOG4106A8V	Protein CrcB homolog
C7M45_RS08530	ENOG4105D01	(LipO)protein
C7M45_RS08535	ENOG4105CHR	reductase
C7M45_RS08540	ENOG4105CUB	amino acid
C7M45_RS08545	ENOG4106IPI	cyclase, family
C7M45_RS08550	ENOG4105K63	Thioredoxin
C7M45_RS08555	ENOG4105CH2	amidohydrolase
C7M45_RS08560	ENOG4105EAB	amino acid AbC transporter
C7M45_RS08570	ENOG4108HW4	amino acid AbC transporter
C7M45_RS08575	ENOG4108XSB	acetyltransferase, (GNAT) family
C7M45_RS08595	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
C7M45_RS08610	ENOG4105EDW	glycosyl transferase, family 39
C7M45_RS08620	ENOG4105CJ1	ABC, transporter
C7M45_RS08635	ENOG4105DWF	phosphomethylpyrimidine kinase
C7M45_RS08700	ENOG4105CHR	reductase
C7M45_RS08715	ENOG4105C7J	ABC transporter, permease
C7M45_RS08735	ENOG4105UIB	(ABC) transporter
C7M45_RS08740	ENOG4108JQ9	ABC transporter
C7M45_RS08775	ENOG4105EMV	Major Facilitator
C7M45_RS08785	ENOG4107ZYR	domain protein
C7M45_RS08800	ENOG4105KIS	phospholipid-binding protein
C7M45_RS08805	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
C7M45_RS08810	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
C7M45_RS08815	ENOG4105CAS	nag kinase
C7M45_RS08820	ENOG4105C8Y	Acetylornithine aminotransferase
C7M45_RS08840	ENOG4105DA5	(ABC) transporter
C7M45_RS08850	ENOG4105DVE	abc transporter atp-binding protein
C7M45_RS08855	ENOG4105W8V	TRANSCRIPTIONAl REGULATOR GntR family
C7M45_RS08860	ENOG4105NA0	Transcriptional regulator
C7M45_RS08870	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
C7M45_RS08875	ENOG4105C34	Pseudouridine synthase
C7M45_RS08885	ENOG4105CG5	Glycosyl transferase (Group 1
C7M45_RS08890	ENOG4105E0M	Sulfatase
C7M45_RS08895	ENOG41082BV	acetyltransferase
C7M45_RS08910	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
C7M45_RS08915	ENOG4105CZM	Major Facilitator
C7M45_RS09020	ENOG4105CQP	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
C7M45_RS09025	ENOG4108IPT	Naphthoate synthase
C7M45_RS09040	ENOG41089G2	accessory Sec system protein Asp2
C7M45_RS09055	ENOG4108NMT	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon (By similarity)
C7M45_RS09070	ENOG4108V06	Glutathione peroxidase
C7M45_RS09075	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
C7M45_RS09080	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
C7M45_RS09085	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
C7M45_RS09095	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
C7M45_RS09100	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
C7M45_RS09120	ENOG4108HCJ	Hydrolase
C7M45_RS09125	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
C7M45_RS09135	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
C7M45_RS09140	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
C7M45_RS09150	ENOG4105M7T	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
C7M45_RS09155	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
C7M45_RS09175	ENOG4108UPS	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity)
C7M45_RS09180	ENOG4105DUM	transcriptional regulator, lysR family
C7M45_RS09185	ENOG4105HMI	Membrane
C7M45_RS09215	ENOG4107R39	(ABC) transporter
C7M45_RS09220	ENOG4107RBB	ABC transporter, permease
C7M45_RS09235	ENOG41067S9	phage shock protein C, PspC
C7M45_RS09250	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
C7M45_RS09255	ENOG4105C5I	Dehydrogenase
C7M45_RS09260	ENOG4105C09	Bile acid
C7M45_RS09265	ENOG4105VG1	fes assembly suf system protein
C7M45_RS09270	ENOG4105C01	Dihydroxy-acid dehydratase
C7M45_RS09280	ENOG4105C3K	feS assembly ATPase SufC
C7M45_RS09285	ENOG4105JRK	feS assembly protein SufD
C7M45_RS09290	ENOG4105C9B	Cysteine desulfurase
C7M45_RS09295	ENOG4108UNV	SUF system FeS assembly protein, NifU family
C7M45_RS09300	ENOG4105DIW	FeS assembly protein SUFB
C7M45_RS09305	ENOG4105VG1	fes assembly suf system protein
C7M45_RS09315	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
C7M45_RS09320	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
C7M45_RS09325	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
C7M45_RS09330	ENOG4108KUU	Inner membrane metabolite transport protein ydjE
C7M45_RS09355	ENOG4105D9G	High-affinity
C7M45_RS09365	ENOG4105CEY	Amp-dependent synthetase and ligase
C7M45_RS09370	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
C7M45_RS09375	ENOG4107XSR	periplasmic solute binding protein
C7M45_RS09395	ENOG410605W	Major Facilitator
C7M45_RS09405	ENOG4105CPC	Aldo Keto reductase
C7M45_RS09415	ENOG4107SET	aldo keto reductase
C7M45_RS09420	ENOG4105KVH	Transcriptional regulator
C7M45_RS09425	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
C7M45_RS09435	ENOG4105DFD	Na H antiporter
C7M45_RS09440	ENOG4105C85	amino acid
C7M45_RS09445	ENOG4105W8I	Transcriptional regulator
C7M45_RS09455	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
C7M45_RS09480	ENOG410667J	hydrolase
C7M45_RS09515	ENOG41064BZ	L-xylulose 5-phosphate 3-epimerase
C7M45_RS09520	ENOG4107R0P	L-ribulose-5-phosphate 4-epimerase
C7M45_RS09580	ENOG4105C9U	ATP-dependent DNA helicase RecQ
C7M45_RS09590	ENOG4108V7D	UPF0397 protein
C7M45_RS09595	ENOG4108JJB	ABC transporter
C7M45_RS09605	ENOG4107QSE	Dipeptidase
C7M45_RS09610	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
C7M45_RS09615	ENOG4108UUM	single-stranded DNA-binding protein
C7M45_RS09620	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
C7M45_RS09630	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
C7M45_RS09635	ENOG4105CDU	Replicative dna helicase
C7M45_RS09645	ENOG4108Z66	YbaK ebsC protein
C7M45_RS09650	ENOG4108TZY	GntR Family Transcriptional Regulator
C7M45_RS09655	ENOG4107QRI	Phosphoketolase
C7M45_RS09660	ENOG4105DKW	ABC transporter
C7M45_RS09675	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
C7M45_RS09680	ENOG4105C7B	Threonine dehydratase
C7M45_RS09690	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
C7M45_RS09705	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
C7M45_RS09710	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
C7M45_RS09730	ENOG4105C0H	protease
C7M45_RS09735	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
C7M45_RS09740	ENOG4105ECB	domain protein
C7M45_RS09745	ENOG41062ES	Transcriptional regulator
C7M45_RS09750	ENOG4108IDQ	Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX (By similarity)
C7M45_RS09755	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
C7M45_RS09760	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
C7M45_RS09770	ENOG4105BZ1	(ABC) transporter
C7M45_RS09775	ENOG4105BZ1	(ABC) transporter
C7M45_RS09780	ENOG4105CDA	abc transporter atp-binding protein
C7M45_RS09785	ENOG4105CT1	(ABC) transporter
C7M45_RS09790	ENOG4105EAD	ABC transporter
C7M45_RS09795	ENOG4105DRP	amino acid AbC transporter
C7M45_RS09800	ENOG4108J59	Extracellular solute-binding protein, family 5
C7M45_RS09805	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
C7M45_RS09810	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
C7M45_RS09820	ENOG4108JQ7	(ABC) transporter
C7M45_RS09825	ENOG4105C9K	Endothelin-converting enzyme 1
C7M45_RS09855	ENOG4105BZA	Phosphoglycerate kinase
C7M45_RS09860	ENOG4107RGD	Major Facilitator superfamily
C7M45_RS09885	ENOG4105C5H	ABC transporter
C7M45_RS09980	ENOG4106A8V	Protein CrcB homolog
C7M45_RS09985	ENOG4105CMQ	Chloride channel
C7M45_RS10015	ENOG4105K63	Thioredoxin
C7M45_RS10020	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
C7M45_RS10025	ENOG4105VPX	protein, conserved in bacteria
C7M45_RS10050	ENOG4105HUF	DNA protection during starvation protein
C7M45_RS10055	ENOG4105IJJ	transcriptional regulator, crp fnr family
C7M45_RS10085	ENOG4105C4B	ABC transporter, permease
C7M45_RS10090	ENOG41083J0	(ABC) transporter
C7M45_RS10100	ENOG4108UXE	Protein tyrosine phosphatase
C7M45_RS10190	ENOG4107QJE	Chromosome Partitioning Protein
C7M45_RS10200	ENOG4108RG0	uracil-dna glycosylase
C7M45_RS10205	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
C7M45_RS10245	ENOG4105C3M	thioredoxin reductase
C7M45_RS10255	ENOG4105K63	Thioredoxin
C7M45_RS10275	ENOG4108IYH	Dna topoisomerase
C7M45_RS10410	ENOG4105NA0	Transcriptional regulator
C7M45_RS10440	ENOG4105MN3	Resolvase
C7M45_RS10445	ENOG4108Z40	Transcriptional regulator
C7M45_RS10450	ENOG4105CIS	alcohol dehydrogenase
C7M45_RS10470	ENOG4105DC8	reductase
C7M45_RS10480	ENOG4105C3M	thioredoxin reductase
C7M45_RS10495	ENOG4105K63	Thioredoxin