locus-tag	class	description
ARA02_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ARA02_RS00010	COG0592	DNA-directed DNA polymerase activity
ARA02_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ARA02_RS00025	COG0187	DNA topoisomerase II activity
ARA02_RS00035	COG0386	Belongs to the glutathione peroxidase family
ARA02_RS00065	COG1073	alpha beta
ARA02_RS00080	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
ARA02_RS00085	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ARA02_RS00090	COG0436	Aminotransferase
ARA02_RS00190	COG2814	Major facilitator Superfamily
ARA02_RS00215	COG1368	sulfuric ester hydrolase activity
ARA02_RS00220	COG0438	transferase activity, transferring glycosyl groups
ARA02_RS00230	COG0564	pseudouridine synthase activity
ARA02_RS00235	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ARA02_RS00250	COG1725	Transcriptional regulator
ARA02_RS00255	COG1131	(ABC) transporter
ARA02_RS00265	COG1131	(ABC) transporter
ARA02_RS00275	COG0656	L-ascorbic acid biosynthetic process
ARA02_RS00285	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ARA02_RS00295	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ARA02_RS00300	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ARA02_RS00305	COG1881	PFAM PEBP family protein
ARA02_RS00320	COG0569	domain protein
ARA02_RS00325	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ARA02_RS00330	COG2271	Major facilitator Superfamily
ARA02_RS00355	COG3845	ABC transporter
ARA02_RS00360	COG4603	Belongs to the binding-protein-dependent transport system permease family
ARA02_RS00365	COG1079	Belongs to the binding-protein-dependent transport system permease family
ARA02_RS00380	COG4120	Belongs to the binding-protein-dependent transport system permease family
ARA02_RS00390	COG1396	sequence-specific DNA binding
ARA02_RS00455	COG0351	phosphomethylpyrimidine kinase
ARA02_RS00470	COG1131	(ABC) transporter
ARA02_RS00480	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ARA02_RS00485	COG0463	Glycosyl transferase, family 2
ARA02_RS00495	COG0446	pyridine nucleotide-disulphide oxidoreductase
ARA02_RS00515	COG0456	acetyltransferase
ARA02_RS00520	COG0765	amino acid transport
ARA02_RS00525	COG1126	abc transporter atp-binding protein
ARA02_RS00530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ARA02_RS00535	COG1473	amidohydrolase
ARA02_RS00540	COG3118	belongs to the thioredoxin family
ARA02_RS00545	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
ARA02_RS00550	COG0531	amino acid
ARA02_RS00560	COG1464	Belongs to the NlpA lipoprotein family
ARA02_RS00570	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ARA02_RS00575	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ARA02_RS00580	COG1307	EDD domain protein, DegV family
ARA02_RS00585	COG1272	protein, Hemolysin III
ARA02_RS00600	COG2115	Belongs to the xylose isomerase family
ARA02_RS00615	COG1968	undecaprenyl-diphosphatase activity
ARA02_RS00630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ARA02_RS00635	COG0765	amino acid transport
ARA02_RS00640	COG0765	amino acid transport
ARA02_RS00645	COG1126	abc transporter atp-binding protein
ARA02_RS00650	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ARA02_RS00660	COG4720	Psort location CytoplasmicMembrane, score
ARA02_RS00665	COG0351	phosphomethylpyrimidine kinase
ARA02_RS00680	COG1012	belongs to the aldehyde dehydrogenase family
ARA02_RS00680	COG1454	alcohol dehydrogenase
ARA02_RS00685	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ARA02_RS00720	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ARA02_RS00730	COG0756	dUTP diphosphatase activity
ARA02_RS00745	COG1309	transcriptional regulator
ARA02_RS00750	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ARA02_RS00755	COG0215	cysteine-tRNA ligase activity
ARA02_RS00855	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ARA02_RS00860	COG0653	protein targeting
ARA02_RS00865	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ARA02_RS00870	COG0542	response to heat
ARA02_RS00880	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ARA02_RS00885	COG0049	tRNA binding
ARA02_RS00890	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ARA02_RS00895	COG2807	transmembrane transport
ARA02_RS00900	COG3842	ATPase activity
ARA02_RS00905	COG1177	transmembrane transport
ARA02_RS00910	COG1177	transmembrane transport
ARA02_RS00920	COG0051	transcription antitermination factor activity, RNA binding
ARA02_RS00925	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ARA02_RS00930	COG0088	Forms part of the polypeptide exit tunnel
ARA02_RS00935	COG0089	rRNA binding
ARA02_RS00940	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ARA02_RS00945	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ARA02_RS00950	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ARA02_RS00955	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ARA02_RS00960	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ARA02_RS00965	COG0255	Belongs to the universal ribosomal protein uL29 family
ARA02_RS00970	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ARA02_RS00975	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ARA02_RS00980	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ARA02_RS00985	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ARA02_RS00990	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ARA02_RS00995	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ARA02_RS01000	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ARA02_RS01005	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ARA02_RS01010	COG1841	ribosomal large subunit assembly
ARA02_RS01015	COG0200	Binds to the 23S rRNA
ARA02_RS01025	COG0563	adenylate kinase activity
ARA02_RS01030	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ARA02_RS01035	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ARA02_RS01040	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ARA02_RS01045	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ARA02_RS01050	COG0202	RNA polymerase activity
ARA02_RS01055	COG0203	ribosomal protein L17
ARA02_RS01060	COG0142	geranyltranstransferase activity
ARA02_RS01070	COG1122	ATPase activity
ARA02_RS01075	COG1122	ATPase activity
ARA02_RS01080	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ARA02_RS01085	COG0101	tRNA pseudouridine synthase activity
ARA02_RS01095	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ARA02_RS01100	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ARA02_RS01135	COG0149	triose-phosphate isomerase activity
ARA02_RS01140	COG0148	phosphopyruvate hydratase activity
ARA02_RS01145	COG0519	Catalyzes the synthesis of GMP from XMP
ARA02_RS01155	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ARA02_RS01165	COG1739	Uncharacterized protein family UPF0029
ARA02_RS01170	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
ARA02_RS01175	COG1040	competence protein
ARA02_RS01190	COG0588	phosphoglycerate mutase activity
ARA02_RS01195	COG1253	flavin adenine dinucleotide binding
ARA02_RS01200	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ARA02_RS01205	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ARA02_RS01210	COG1780	Probably involved in ribonucleotide reductase function
ARA02_RS01225	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ARA02_RS01240	COG1077	Cell shape determining protein MreB Mrl
ARA02_RS01250	COG0772	Belongs to the SEDS family
ARA02_RS01260	COG1181	Belongs to the D-alanine--D-alanine ligase family
ARA02_RS01270	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ARA02_RS01285	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ARA02_RS01290	COG0081	regulation of translation
ARA02_RS01295	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ARA02_RS01300	COG0222	ribosome binding
ARA02_RS01305	COG2813	Specifically methylates the guanine in position
ARA02_RS01310	COG0590	tRNA wobble adenosine to inosine editing
ARA02_RS01325	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ARA02_RS01330	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ARA02_RS01340	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ARA02_RS01345	COG3870	Protein conserved in bacteria
ARA02_RS01350	COG0470	DNA polymerase III
ARA02_RS01365	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ARA02_RS01385	COG1609	Transcriptional regulator
ARA02_RS01395	COG1621	beta-fructofuranosidase activity
ARA02_RS01400	COG1940	carbohydrate kinase activity
ARA02_RS01415	COG1428	Deoxynucleoside kinase
ARA02_RS01420	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ARA02_RS01425	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ARA02_RS01435	COG0492	ferredoxin-NADP+ reductase activity
ARA02_RS01445	COG1418	mRNA catabolic process
ARA02_RS01450	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ARA02_RS01450	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ARA02_RS01455	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
ARA02_RS01455	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
ARA02_RS01465	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ARA02_RS01490	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ARA02_RS01500	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ARA02_RS01505	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ARA02_RS01515	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ARA02_RS01520	COG1028	Short-chain dehydrogenase reductase Sdr
ARA02_RS01525	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ARA02_RS01530	COG0511	ligase activity, forming carbon-carbon bonds
ARA02_RS01540	COG0439	Biotin carboxylase
ARA02_RS01545	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ARA02_RS01565	COG0525	valine-tRNA ligase activity
ARA02_RS01570	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ARA02_RS01585	COG3103	Sh3 type 3 domain protein
ARA02_RS01585	COG1388	LysM domain
ARA02_RS01585	COG0791	NLP P60 protein
ARA02_RS01595	COG0768	penicillin binding
ARA02_RS01600	COG0640	Transcriptional regulator
ARA02_RS01610	COG0577	efflux transmembrane transporter activity
ARA02_RS01610	COG1136	(ABC) transporter
ARA02_RS01615	COG1316	TRANSCRIPTIONal
ARA02_RS01640	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ARA02_RS01650	COG1914	H( )-stimulated, divalent metal cation uptake system
ARA02_RS01660	COG0640	Transcriptional regulator
ARA02_RS01675	COG1957	nucleoside hydrolase
ARA02_RS01680	COG0357	Ribosomal RNA small subunit methyltransferase G
ARA02_RS01685	COG1192	Involved in chromosome partitioning
ARA02_RS01690	COG1475	DNA binding
ARA02_RS01695	COG4481	Protein conserved in bacteria
ARA02_RS01700	COG0012	GTP binding
ARA02_RS01710	COG0745	RESPONSE REGULATOR receiver
ARA02_RS01715	COG2205	protein histidine kinase activity
ARA02_RS01725	COG0363	glucosamine-6-phosphate deaminase activity
ARA02_RS01730	COG0166	Belongs to the GPI family
ARA02_RS01740	COG3448	diguanylate cyclase activity
ARA02_RS01740	COG4175	Glycine betaine
ARA02_RS01795	COG0765	amino acid transport
ARA02_RS01800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ARA02_RS01805	COG0765	amino acid transport
ARA02_RS01810	COG1126	abc transporter atp-binding protein
ARA02_RS01815	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ARA02_RS01820	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ARA02_RS01825	COG1126	abc transporter atp-binding protein
ARA02_RS01830	COG2814	Major facilitator Superfamily
ARA02_RS01835	COG0343	queuine tRNA-ribosyltransferase activity
ARA02_RS01840	COG1862	Preprotein translocase
ARA02_RS01865	COG0406	alpha-ribazole phosphatase activity
ARA02_RS01880	COG1132	(ABC) transporter
ARA02_RS01885	COG1132	(ABC) transporter
ARA02_RS01890	COG0438	transferase activity, transferring glycosyl groups
ARA02_RS01910	COG1368	sulfuric ester hydrolase activity
ARA02_RS01915	COG0556	nucleotide-excision repair
ARA02_RS01920	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ARA02_RS01925	COG0391	Required for morphogenesis under gluconeogenic growth conditions
ARA02_RS01930	COG1481	regulation of sporulation
ARA02_RS01935	COG0740	serine-type endopeptidase activity
ARA02_RS01945	COG0193	aminoacyl-tRNA hydrolase activity
ARA02_RS01950	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ARA02_RS01955	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ARA02_RS01965	COG0037	tRNA processing
ARA02_RS01975	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ARA02_RS01980	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ARA02_RS01985	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ARA02_RS02010	COG0217	transcriptional regulatory protein
ARA02_RS02015	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ARA02_RS02025	COG2252	PERMEase
ARA02_RS02030	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ARA02_RS02075	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ARA02_RS02085	COG2188	Transcriptional regulator
ARA02_RS02095	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ARA02_RS02105	COG1464	Belongs to the NlpA lipoprotein family
ARA02_RS02140	COG1744	ABC transporter substrate-binding protein PnrA-like
ARA02_RS02145	COG0765	amino acid transport
ARA02_RS02150	COG1126	abc transporter atp-binding protein
ARA02_RS02155	COG0765	amino acid transport
ARA02_RS02180	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ARA02_RS02185	COG1733	regulation of RNA biosynthetic process
ARA02_RS02190	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ARA02_RS02195	COG0072	phenylalanine-tRNA ligase activity
ARA02_RS02195	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ARA02_RS02200	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ARA02_RS02205	COG0254	rRNA binding
ARA02_RS02210	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ARA02_RS02215	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ARA02_RS02235	COG2814	Major facilitator Superfamily
ARA02_RS02240	COG2003	Belongs to the UPF0758 family
ARA02_RS02245	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ARA02_RS02250	COG2131	deaminase
ARA02_RS02255	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ARA02_RS02260	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ARA02_RS02270	COG4537	Required for transformation and DNA binding
ARA02_RS02300	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ARA02_RS02310	COG4975	Glucose uptake
ARA02_RS02315	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ARA02_RS02350	COG0683	leucine binding
ARA02_RS02365	COG0411	ABC transporter
ARA02_RS02375	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
ARA02_RS02385	COG0352	thiamine-phosphate diphosphorylase activity
ARA02_RS02390	COG1012	belongs to the aldehyde dehydrogenase family
ARA02_RS02430	COG4493	Belongs to the UPF0637 family
ARA02_RS02435	COG0025	NhaP-type Na H and K H
ARA02_RS02440	COG1609	Transcriptional regulator
ARA02_RS02460	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ARA02_RS02470	COG0308	aminopeptidase N
ARA02_RS02480	COG2936	dipeptidyl-peptidase activity
ARA02_RS02490	COG1263	PTS System
ARA02_RS02490	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ARA02_RS02490	COG2190	(PTS) system
ARA02_RS02495	COG0366	Alpha amylase catalytic
ARA02_RS02500	COG2188	Transcriptional regulator
ARA02_RS02505	COG1078	dGTPase activity
ARA02_RS02515	COG3343	RNA polymerase activity
ARA02_RS02525	COG1113	amino acid transport
ARA02_RS02530	COG1268	BioY protein
ARA02_RS02540	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
ARA02_RS02540	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
ARA02_RS02545	COG0504	CTP synthase activity
ARA02_RS02550	COG0322	excinuclease ABC activity
ARA02_RS02555	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ARA02_RS02560	COG0028	Belongs to the TPP enzyme family
ARA02_RS02570	COG2309	aminopeptidase activity
ARA02_RS02580	COG0673	inositol 2-dehydrogenase activity
ARA02_RS02585	COG0513	Belongs to the DEAD box helicase family
ARA02_RS02590	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ARA02_RS02600	COG0237	dephospho-CoA kinase activity
ARA02_RS02610	COG1484	DNA-dependent DNA replication
ARA02_RS02635	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ARA02_RS02640	COG0416	fatty acid biosynthetic process
ARA02_RS02645	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ARA02_RS02650	COG3091	SprT-like family
ARA02_RS02655	COG0561	phosphatase activity
ARA02_RS02675	COG1609	Transcriptional regulator
ARA02_RS02680	COG2755	lipolytic protein G-D-S-L family
ARA02_RS02680	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ARA02_RS02685	COG2814	Major facilitator Superfamily
ARA02_RS02700	COG3527	Alpha-acetolactate decarboxylase
ARA02_RS02705	COG1737	Transcriptional regulator
ARA02_RS02710	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
ARA02_RS02725	COG0531	amino acid
ARA02_RS02735	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ARA02_RS02740	COG4472	Bacterial protein of unknown function (DUF965)
ARA02_RS02745	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ARA02_RS02750	COG3906	Belongs to the UPF0473 family
ARA02_RS02755	COG1271	oxidase subunit
ARA02_RS02760	COG1294	oxidase, subunit
ARA02_RS02765	COG4988	ABC transporter
ARA02_RS02770	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ARA02_RS02775	COG1705	Flagellar rod assembly protein muramidase FlgJ
ARA02_RS02775	COG3942	CHAP domain
ARA02_RS02795	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ARA02_RS02810	COG0542	response to heat
ARA02_RS02815	COG1077	Cell shape determining protein MreB Mrl
ARA02_RS02830	COG0765	amino acid transport
ARA02_RS02840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ARA02_RS02850	COG0612	Peptidase, M16
ARA02_RS02855	COG0612	Peptidase, M16
ARA02_RS02860	COG1426	Protein conserved in bacteria
ARA02_RS02865	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ARA02_RS02870	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ARA02_RS02875	COG0745	RESPONSE REGULATOR receiver
ARA02_RS02880	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ARA02_RS02895	COG0573	inorganic phosphate transmembrane transporter activity
ARA02_RS02900	COG0581	inorganic phosphate transmembrane transporter activity
ARA02_RS02905	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ARA02_RS02910	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ARA02_RS02915	COG0704	Plays a role in the regulation of phosphate uptake
ARA02_RS02925	COG1950	PFAM Membrane protein of
ARA02_RS02930	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
ARA02_RS02935	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ARA02_RS02940	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ARA02_RS02945	COG0492	ferredoxin-NADP+ reductase activity
ARA02_RS02965	COG1609	Transcriptional regulator
ARA02_RS02975	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ARA02_RS02980	COG0335	large ribosomal subunit rRNA binding
ARA02_RS02985	COG1719	4-vinyl reductase, 4VR
ARA02_RS02990	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ARA02_RS02995	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ARA02_RS03005	COG2255	four-way junction helicase activity
ARA02_RS03015	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ARA02_RS03020	COG0584	glycerophosphoryl diester phosphodiesterase
ARA02_RS03025	COG0632	four-way junction helicase activity
ARA02_RS03030	COG1428	Deoxynucleoside kinase
ARA02_RS03035	COG1970	mechanosensitive ion channel activity
ARA02_RS03040	COG0577	efflux transmembrane transporter activity
ARA02_RS03045	COG1136	(ABC) transporter
ARA02_RS03050	COG4684	Psort location CytoplasmicMembrane, score
ARA02_RS03060	COG4684	Psort location CytoplasmicMembrane, score
ARA02_RS03080	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ARA02_RS03085	COG1126	abc transporter atp-binding protein
ARA02_RS03090	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ARA02_RS03100	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ARA02_RS03110	COG0671	phosphoesterase, PA-phosphatase related
ARA02_RS03115	COG0495	leucyl-tRNA aminoacylation
ARA02_RS03120	COG2244	polysaccharide biosynthetic process
ARA02_RS03135	COG1704	LemA family
ARA02_RS03140	COG0501	Belongs to the peptidase M48B family
ARA02_RS03145	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ARA02_RS03150	COG1942	4-Oxalocrotonate Tautomerase
ARA02_RS03160	COG3237	CsbD-like
ARA02_RS03165	COG0517	IMP dehydrogenase activity
ARA02_RS03165	COG0516	GMP reductase activity
ARA02_RS03170	COG0517	IMP dehydrogenase activity
ARA02_RS03170	COG0516	GMP reductase activity
ARA02_RS03185	COG3331	DNA recombination
ARA02_RS03195	COG4474	Belongs to the UPF0398 family
ARA02_RS03200	COG3599	regulation of cell shape
ARA02_RS03210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ARA02_RS03215	COG2706	6-phosphogluconolactonase activity
ARA02_RS03220	COG0628	permease
ARA02_RS03235	COG1674	ftsk spoiiie
ARA02_RS03235	COG1280	lysine exporter protein (LysE YggA)
ARA02_RS03240	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ARA02_RS03245	COG1113	amino acid transport
ARA02_RS03250	COG0586	Pfam SNARE associated Golgi protein
ARA02_RS03260	COG3001	Fructosamine kinase
ARA02_RS03270	COG2171	N-acyltransferase activity
ARA02_RS03275	COG1473	amidohydrolase
ARA02_RS03280	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ARA02_RS03285	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ARA02_RS03295	COG3557	Belongs to the UPF0374 family
ARA02_RS03300	COG0705	Rhomboid family
ARA02_RS03310	COG1940	carbohydrate kinase activity
ARA02_RS03320	COG2357	RelA SpoT domain protein
ARA02_RS03325	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ARA02_RS03330	COG0564	pseudouridine synthase activity
ARA02_RS03335	COG2239	Acts as a magnesium transporter
ARA02_RS03345	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
ARA02_RS03350	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ARA02_RS03355	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ARA02_RS03360	COG4589	Belongs to the CDS family
ARA02_RS03365	COG0750	zinc metalloprotease
ARA02_RS03370	COG0442	prolyl-tRNA aminoacylation
ARA02_RS03375	COG2176	DNA-directed DNA polymerase activity
ARA02_RS03395	COG1744	ABC transporter substrate-binding protein PnrA-like
ARA02_RS03410	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ARA02_RS03415	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ARA02_RS03425	COG0667	Aldo Keto reductase
ARA02_RS03430	COG0151	Belongs to the GarS family
ARA02_RS03435	COG2759	Belongs to the formate--tetrahydrofolate ligase family
ARA02_RS03440	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ARA02_RS03445	COG1278	Cold shock
ARA02_RS03450	COG0494	nUDIX hydrolase
ARA02_RS03460	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ARA02_RS03465	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ARA02_RS03470	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ARA02_RS03485	COG3583	domain protein
ARA02_RS03485	COG5492	domain, Protein
ARA02_RS03485	COG1621	beta-fructofuranosidase activity
ARA02_RS03490	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ARA02_RS03490	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ARA02_RS03495	COG3764	Sortase (surface protein transpeptidase)
ARA02_RS03505	COG0789	Transcriptional regulator
ARA02_RS03510	COG0174	glutamine synthetase
ARA02_RS03515	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ARA02_RS03520	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ARA02_RS03525	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ARA02_RS03530	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ARA02_RS03540	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ARA02_RS03550	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ARA02_RS03555	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ARA02_RS03565	COG0420	3'-5' exonuclease activity
ARA02_RS03570	COG4717	serine-type aminopeptidase activity
ARA02_RS03590	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ARA02_RS03600	COG0095	Lipoate-protein ligase
ARA02_RS03615	COG0508	dehydrogenase complex catalyzes the overall conversion of
ARA02_RS03625	COG2267	carboxylic ester hydrolase activity
ARA02_RS03630	COG0584	glycerophosphoryl diester phosphodiesterase
ARA02_RS03650	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ARA02_RS03655	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ARA02_RS03665	COG0351	phosphomethylpyrimidine kinase
ARA02_RS03670	COG1169	isochorismate synthase
ARA02_RS03675	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
ARA02_RS03695	COG0617	tRNA 3'-terminal CCA addition
ARA02_RS03705	COG1307	EDD domain protein, DegV family
ARA02_RS03710	COG1957	nucleoside hydrolase
ARA02_RS03720	COG2755	lipolytic protein G-D-S-L family
ARA02_RS03730	COG4479	Belongs to the UPF0346 family
ARA02_RS03735	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
ARA02_RS03740	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ARA02_RS03750	COG1122	ATPase activity
ARA02_RS03765	COG2384	SAM-dependent methyltransferase
ARA02_RS03770	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ARA02_RS03785	COG0587	DNA-directed DNA polymerase activity
ARA02_RS03795	COG0004	ammonium transporteR
ARA02_RS03800	COG1702	phosphate starvation-inducible protein PhoH
ARA02_RS03805	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ARA02_RS03815	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ARA02_RS03820	COG1381	Involved in DNA repair and RecF pathway recombination
ARA02_RS03825	COG0252	asparaginase activity
ARA02_RS03835	COG0527	aspartate kinase activity
ARA02_RS03840	COG0083	homoserine kinase activity
ARA02_RS03845	COG0460	homoserine dehydrogenase
ARA02_RS03850	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ARA02_RS03855	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ARA02_RS03860	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ARA02_RS03865	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ARA02_RS03890	COG1609	Transcriptional regulator
ARA02_RS03895	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ARA02_RS03915	COG0517	IMP dehydrogenase activity
ARA02_RS03915	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ARA02_RS03920	COG2877	3-deoxy-8-phosphooctulonate synthase activity
ARA02_RS03935	COG1121	(ABC) transporter
ARA02_RS03940	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ARA02_RS03960	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ARA02_RS03965	COG0415	Belongs to the DNA photolyase family
ARA02_RS03970	COG0577	efflux transmembrane transporter activity
ARA02_RS03985	COG2409	Drug exporters of the RND superfamily
ARA02_RS03985	COG1033	growth of symbiont in host cell
ARA02_RS04020	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ARA02_RS04020	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ARA02_RS04025	COG0307	riboflavin synthase, alpha
ARA02_RS04035	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ARA02_RS04040	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ARA02_RS04045	COG2814	Major facilitator Superfamily
ARA02_RS04055	COG1609	Transcriptional regulator
ARA02_RS04075	COG0693	protein deglycase activity
ARA02_RS04080	COG0745	RESPONSE REGULATOR receiver
ARA02_RS04085	COG5002	protein histidine kinase activity
ARA02_RS04090	COG1136	(ABC) transporter
ARA02_RS04100	COG0583	DNA-binding transcription factor activity
ARA02_RS04105	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ARA02_RS04110	COG1045	serine acetyltransferase
ARA02_RS04120	COG0667	Aldo Keto reductase
ARA02_RS04135	COG1874	Beta-galactosidase
ARA02_RS04165	COG0789	Transcriptional regulator
ARA02_RS04180	COG1609	Transcriptional regulator
ARA02_RS04185	COG2160	L-arabinose isomerase activity
ARA02_RS04205	COG1028	Short-chain dehydrogenase reductase Sdr
ARA02_RS04215	COG2261	transglycosylase associated protein
ARA02_RS04240	COG2261	transglycosylase associated protein
ARA02_RS04250	COG2814	Major facilitator Superfamily
ARA02_RS04255	COG5039	Polysaccharide pyruvyl transferase
ARA02_RS04260	COG1472	Belongs to the glycosyl hydrolase 3 family
ARA02_RS04290	COG2211	Major facilitator Superfamily
ARA02_RS04290	COG2190	(PTS) system
ARA02_RS04295	COG1609	Transcriptional regulator
ARA02_RS04305	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ARA02_RS04310	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
ARA02_RS04315	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ARA02_RS04340	COG1609	Transcriptional regulator
ARA02_RS04355	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ARA02_RS04365	COG0366	Alpha amylase catalytic
ARA02_RS04375	COG0366	Alpha amylase catalytic
ARA02_RS04390	COG2723	6-phospho-beta-galactosidase activity
ARA02_RS04400	COG1956	GAF domain-containing protein
ARA02_RS04405	COG2244	polysaccharide biosynthetic process
ARA02_RS04410	COG1609	Transcriptional regulator
ARA02_RS04440	COG1215	transferase activity, transferring glycosyl groups
ARA02_RS04455	COG0300	oxidoreductase activity
ARA02_RS04465	COG0477	Major facilitator Superfamily
ARA02_RS04470	COG1063	alcohol dehydrogenase
ARA02_RS04480	COG1129	ABC transporter
ARA02_RS04485	COG1573	uracil-dna glycosylase
ARA02_RS04490	COG4720	Psort location CytoplasmicMembrane, score
ARA02_RS04505	COG0693	protein deglycase activity
ARA02_RS04515	COG0436	Aminotransferase
ARA02_RS04520	COG1028	Short-chain dehydrogenase reductase Sdr
ARA02_RS04530	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ARA02_RS04535	COG1619	proteins homologs of microcin C7 resistance protein MccF
ARA02_RS04565	COG1447	Phosphotransferase system cellobiose-specific component IIA
ARA02_RS04575	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ARA02_RS04595	COG1028	Short-chain dehydrogenase reductase Sdr
ARA02_RS04605	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
ARA02_RS04625	COG2723	6-phospho-beta-galactosidase activity
ARA02_RS04640	COG1733	regulation of RNA biosynthetic process
ARA02_RS04645	COG1846	Transcriptional regulator
ARA02_RS04665	COG1442	glycosyl transferase family 8
ARA02_RS04670	COG1121	(ABC) transporter
ARA02_RS04675	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ARA02_RS04685	COG3527	Alpha-acetolactate decarboxylase
ARA02_RS04695	COG0745	RESPONSE REGULATOR receiver
ARA02_RS04700	COG5002	protein histidine kinase activity
ARA02_RS04720	COG1316	TRANSCRIPTIONal
ARA02_RS04725	COG1846	Transcriptional regulator
ARA02_RS04745	COG0656	L-ascorbic acid biosynthetic process
ARA02_RS04750	COG0789	Transcriptional regulator
ARA02_RS04755	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ARA02_RS04765	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ARA02_RS04780	COG2364	Membrane
ARA02_RS04785	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ARA02_RS04800	COG0028	Belongs to the TPP enzyme family
ARA02_RS04805	COG0071	Belongs to the small heat shock protein (HSP20) family
ARA02_RS04810	COG0702	epimerase
ARA02_RS04820	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ARA02_RS04825	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ARA02_RS04835	COG3340	Belongs to the peptidase S51 family
ARA02_RS04845	COG1733	regulation of RNA biosynthetic process
ARA02_RS04850	COG0577	efflux transmembrane transporter activity
ARA02_RS04850	COG1136	(ABC) transporter
ARA02_RS04960	COG1309	transcriptional regulator
ARA02_RS04965	COG0604	alcohol dehydrogenase
ARA02_RS05010	COG0586	Pfam SNARE associated Golgi protein
ARA02_RS05015	COG0745	RESPONSE REGULATOR receiver
ARA02_RS05025	COG0671	phosphoesterase, PA-phosphatase related
ARA02_RS05040	COG0463	Glycosyl transferase, family 2
ARA02_RS05120	COG0542	response to heat
ARA02_RS05145	COG1192	Involved in chromosome partitioning
ARA02_RS05190	COG2364	Membrane
ARA02_RS05230	COG2826	transposase and inactivated derivatives, IS30 family
ARA02_RS05235	COG0358	DNA primase activity
ARA02_RS05240	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ARA02_RS05250	COG1028	Short-chain dehydrogenase reductase Sdr
ARA02_RS05260	COG0626	cystathionine gamma-synthase activity
ARA02_RS05265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ARA02_RS05270	COG0765	amino acid transport
ARA02_RS05275	COG1126	abc transporter atp-binding protein
ARA02_RS05280	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ARA02_RS05285	COG0436	Aminotransferase
ARA02_RS05295	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ARA02_RS05305	COG0537	adenosine 5'-monophosphoramidase activity
ARA02_RS05310	COG1131	(ABC) transporter
ARA02_RS05320	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ARA02_RS05385	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ARA02_RS05395	COG0018	arginyl-trna synthetase
ARA02_RS05400	COG1438	arginine binding
ARA02_RS05405	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ARA02_RS05410	COG3679	Belongs to the UPF0342 family
ARA02_RS05420	COG0540	Belongs to the ATCase OTCase family
ARA02_RS05425	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ARA02_RS05430	COG0505	Belongs to the CarA family
ARA02_RS05435	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ARA02_RS05440	COG0284	orotidine-5'-phosphate decarboxylase activity
ARA02_RS05450	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ARA02_RS05455	COG3763	UPF0154 protein
ARA02_RS05460	COG0204	Acyl-transferase
ARA02_RS05465	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
ARA02_RS05470	COG2827	Endonuclease containing a URI domain
ARA02_RS05475	COG0052	Belongs to the universal ribosomal protein uS2 family
ARA02_RS05480	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ARA02_RS05485	COG0528	UMP kinase activity
ARA02_RS05490	COG0233	cytoplasmic translational termination
ARA02_RS05500	COG0752	glycyl-tRNA synthetase alpha subunit
ARA02_RS05505	COG0751	glycine-tRNA ligase activity
ARA02_RS05510	COG0673	inositol 2-dehydrogenase activity
ARA02_RS05530	COG2264	protein methyltransferase activity
ARA02_RS05535	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ARA02_RS05545	COG0488	(ABC) transporter
ARA02_RS05550	COG3425	synthase
ARA02_RS05570	COG2848	UPF0210 protein
ARA02_RS05600	COG0134	indole-3-glycerol-phosphate synthase activity
ARA02_RS05610	COG0159	tryptophan synthase activity
ARA02_RS05615	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ARA02_RS05620	COG0512	Glutamine amidotransferase of anthranilate synthase
ARA02_RS05625	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ARA02_RS05635	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
ARA02_RS05640	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ARA02_RS05645	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ARA02_RS05650	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ARA02_RS05655	COG0287	Prephenate dehydrogenase
ARA02_RS05660	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ARA02_RS05670	COG0710	3-dehydroquinate dehydratase activity
ARA02_RS05675	COG0352	thiamine-phosphate diphosphorylase activity
ARA02_RS05680	COG2104	thiamine diphosphate biosynthetic process
ARA02_RS05680	COG2022	thiamine diphosphate biosynthetic process
ARA02_RS05685	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ARA02_RS05690	COG2022	thiamine diphosphate biosynthetic process
ARA02_RS05700	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ARA02_RS05705	COG1028	Short-chain dehydrogenase reductase Sdr
ARA02_RS05715	COG2814	Major facilitator Superfamily
ARA02_RS05730	COG2409	Drug exporters of the RND superfamily
ARA02_RS05735	COG4585	Histidine kinase
ARA02_RS05740	COG2197	response regulator
ARA02_RS05775	COG0131	Imidazoleglycerol-phosphate dehydratase
ARA02_RS05775	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ARA02_RS05795	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
ARA02_RS05835	COG0758	DNA mediated transformation
ARA02_RS05840	COG0488	(ABC) transporter
ARA02_RS05845	COG0167	dihydroorotate dehydrogenase activity
ARA02_RS05850	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ARA02_RS05855	COG0860	N-Acetylmuramoyl-L-alanine amidase
ARA02_RS05865	COG2183	response to ionizing radiation
ARA02_RS05875	COG1970	mechanosensitive ion channel activity
ARA02_RS05890	COG0626	cystathionine gamma-synthase activity
ARA02_RS05895	COG1045	serine acetyltransferase
ARA02_RS05905	COG0776	regulation of translation
ARA02_RS05910	COG1160	GTP binding
ARA02_RS05915	COG0539	negative regulation of cytoplasmic translation
ARA02_RS05920	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ARA02_RS05930	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
ARA02_RS05935	COG1187	pseudouridine synthase activity
ARA02_RS05940	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ARA02_RS05945	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ARA02_RS05955	COG4974	Belongs to the 'phage' integrase family
ARA02_RS05960	COG2996	Protein conserved in bacteria
ARA02_RS05965	COG1610	YqeY-like protein
ARA02_RS05970	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ARA02_RS05975	COG0477	Major facilitator Superfamily
ARA02_RS05980	COG2508	Transcriptional regulator
ARA02_RS05985	COG1113	amino acid transport
ARA02_RS05990	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ARA02_RS05995	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ARA02_RS06000	COG0124	histidyl-tRNA synthetase
ARA02_RS06005	COG2017	converts alpha-aldose to the beta-anomer
ARA02_RS06010	COG2207	Transcriptional regulator
ARA02_RS06015	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ARA02_RS06025	COG0667	Aldo Keto reductase
ARA02_RS06030	COG3250	beta-galactosidase activity
ARA02_RS06040	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ARA02_RS06045	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ARA02_RS06055	COG4470	Protein conserved in bacteria
ARA02_RS06060	COG0737	Belongs to the 5'-nucleotidase family
ARA02_RS06070	COG0006	proline dipeptidase activity
ARA02_RS06075	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ARA02_RS06080	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ARA02_RS06120	COG1247	-acetyltransferase
ARA02_RS06125	COG2962	Rard protein
ARA02_RS06155	COG1217	gtp-binding protein TYPA
ARA02_RS06160	COG0483	inositol monophosphate 1-phosphatase activity
ARA02_RS06165	COG4476	Belongs to the UPF0223 family
ARA02_RS06170	COG0242	peptide deformylase activity
ARA02_RS06175	COG0484	heat shock protein binding
ARA02_RS06180	COG0443	Heat shock 70 kDa protein
ARA02_RS06185	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ARA02_RS06190	COG1420	regulation of RNA biosynthetic process
ARA02_RS06195	COG0196	riboflavin kinase activity
ARA02_RS06200	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ARA02_RS06210	COG0436	Aminotransferase
ARA02_RS06215	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ARA02_RS06220	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ARA02_RS06230	COG2740	Nucleic-acid-binding protein implicated in transcription termination
ARA02_RS06235	COG0195	Participates in both transcription termination and antitermination
ARA02_RS06240	COG0779	Required for maturation of 30S ribosomal subunits
ARA02_RS06245	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ARA02_RS06250	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ARA02_RS06255	COG1227	inorganic diphosphatase activity
ARA02_RS06265	COG0187	DNA topoisomerase II activity
ARA02_RS06275	COG1490	D-aminoacyl-tRNA deacylase activity
ARA02_RS06280	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ARA02_RS06300	COG0505	Belongs to the CarA family
ARA02_RS06305	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
ARA02_RS06310	COG0564	pseudouridine synthase activity
ARA02_RS06320	COG0328	RNA-DNA hybrid ribonuclease activity
ARA02_RS06330	COG0436	Aminotransferase
ARA02_RS06335	COG0116	Belongs to the methyltransferase superfamily
ARA02_RS06350	COG0017	Asparaginyl-tRNA synthetase
ARA02_RS06365	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ARA02_RS06365	COG1199	ATP-dependent helicase activity
ARA02_RS06385	COG1304	FMN binding
ARA02_RS06395	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ARA02_RS06400	COG2116	formate transmembrane transporter activity
ARA02_RS06405	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ARA02_RS06410	COG0716	FMN binding
ARA02_RS06420	COG1216	Glycosyl transferase, family 2
ARA02_RS06440	COG0463	Glycosyl transferase, family 2
ARA02_RS06445	COG0562	UDP-galactopyranose mutase
ARA02_RS06465	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ARA02_RS06490	COG0366	Alpha amylase catalytic
ARA02_RS06490	COG5263	repeat protein
ARA02_RS06495	COG0366	Alpha amylase catalytic
ARA02_RS06495	COG5263	repeat protein
ARA02_RS06545	COG1088	dTDP-glucose 4,6-dehydratase activity
ARA02_RS06555	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ARA02_RS06580	COG1216	Glycosyl transferase, family 2
ARA02_RS06590	COG0463	Glycosyl transferase, family 2
ARA02_RS06590	COG1216	Glycosyl transferase, family 2
ARA02_RS06605	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ARA02_RS06610	COG0489	protein tyrosine kinase activity
ARA02_RS06625	COG0024	Methionine aminopeptidase
ARA02_RS06630	COG1316	TRANSCRIPTIONal
ARA02_RS06635	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ARA02_RS06640	COG1114	Component of the transport system for branched-chain amino acids
ARA02_RS06645	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ARA02_RS06650	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ARA02_RS06670	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ARA02_RS06675	COG3142	Participates in the control of copper homeostasis
ARA02_RS06720	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
ARA02_RS06730	COG0165	Argininosuccinate lyase
ARA02_RS06735	COG0137	argininosuccinate synthase activity
ARA02_RS06740	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ARA02_RS06745	COG0217	transcriptional regulatory protein
ARA02_RS06755	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ARA02_RS06760	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ARA02_RS06770	COG0280	phosphate acetyltransferase
ARA02_RS06775	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ARA02_RS06805	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ARA02_RS06810	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
ARA02_RS06810	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ARA02_RS06815	COG1234	tRNA 3'-trailer cleavage
ARA02_RS06820	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ARA02_RS06825	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ARA02_RS06830	COG0336	Belongs to the RNA methyltransferase TrmD family
ARA02_RS06835	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ARA02_RS06845	COG1074	ATP-dependent DNA helicase activity
ARA02_RS06850	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
ARA02_RS06865	COG0228	four-way junction DNA binding
ARA02_RS06890	COG0762	integral membrane protein
ARA02_RS06895	COG1799	cell septum assembly
ARA02_RS06910	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ARA02_RS06915	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ARA02_RS06920	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ARA02_RS06925	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ARA02_RS06930	COG0768	penicillin binding
ARA02_RS06940	COG0275	rRNA processing
ARA02_RS06945	COG2001	Belongs to the MraZ family
ARA02_RS06960	COG1461	Dihydroxyacetone kinase
ARA02_RS06970	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ARA02_RS06975	COG3118	belongs to the thioredoxin family
ARA02_RS06980	COG1564	THIamine pyrophosphokinase
ARA02_RS06985	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ARA02_RS07000	COG0631	protein serine/threonine phosphatase activity
ARA02_RS07005	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ARA02_RS07005	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ARA02_RS07010	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ARA02_RS07015	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ARA02_RS07030	COG3201	nicotinamide mononucleotide transporter
ARA02_RS07035	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ARA02_RS07040	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ARA02_RS07045	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ARA02_RS07055	COG4974	Belongs to the 'phage' integrase family
ARA02_RS07070	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
ARA02_RS07075	COG0544	peptidyl-prolyl cis-trans isomerase activity
ARA02_RS07095	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ARA02_RS07100	COG0708	Exodeoxyribonuclease III
ARA02_RS07105	COG2176	DNA-directed DNA polymerase activity
ARA02_RS07110	COG0456	acetyltransferase
ARA02_RS07115	COG0802	atpase or kinase
ARA02_RS07150	COG0602	queuosine metabolic process
ARA02_RS07155	COG1328	CTP reductase activity
ARA02_RS07160	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ARA02_RS07165	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ARA02_RS07180	COG4172	Belongs to the ABC transporter superfamily
ARA02_RS07195	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ARA02_RS07200	COG0140	phosphoribosyl-ATP diphosphatase activity
ARA02_RS07205	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ARA02_RS07210	COG0107	imidazoleglycerol-phosphate synthase activity
ARA02_RS07215	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ARA02_RS07225	COG0131	Imidazoleglycerol-phosphate dehydratase
ARA02_RS07230	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ARA02_RS07245	COG2199	diguanylate cyclase activity
ARA02_RS07265	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
ARA02_RS07270	COG0561	phosphatase activity
ARA02_RS07280	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ARA02_RS07290	COG0552	protein localization to endoplasmic reticulum
ARA02_RS07295	COG1196	nuclear chromosome segregation
ARA02_RS07300	COG0571	ribonuclease III activity
ARA02_RS07305	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ARA02_RS07330	COG0105	UTP biosynthetic process
ARA02_RS07335	COG4807	Protein conserved in bacteria
ARA02_RS07340	COG3237	CsbD-like
ARA02_RS07345	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ARA02_RS07350	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ARA02_RS07355	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ARA02_RS07360	COG1597	lipid kinase activity
ARA02_RS07370	COG0154	amidase activity
ARA02_RS07375	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ARA02_RS07380	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ARA02_RS07385	COG0268	Binds directly to 16S ribosomal RNA
ARA02_RS07390	COG0513	Belongs to the DEAD box helicase family
ARA02_RS07395	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ARA02_RS07400	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ARA02_RS07405	COG1466	dna polymerase III delta subunit
ARA02_RS07410	COG0658	competence protein
ARA02_RS07410	COG2333	competence protein COMEC
ARA02_RS07415	COG1555	photosystem II stabilization
ARA02_RS07415	COG1596	polysaccharide export
ARA02_RS07420	COG3480	Lon protease (S16) C-terminal proteolytic domain
ARA02_RS07425	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ARA02_RS07430	COG0742	ribosomal rna small subunit methyltransferase
ARA02_RS07440	COG0772	Belongs to the SEDS family
ARA02_RS07445	COG1363	Peptidase, m42
ARA02_RS07450	COG0588	phosphoglycerate mutase activity
ARA02_RS07455	COG0534	Mate efflux family protein
ARA02_RS07460	COG2252	PERMEase
ARA02_RS07465	COG0497	DNA recombination
ARA02_RS07470	COG1438	arginine binding
ARA02_RS07475	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
ARA02_RS07480	COG0142	geranyltranstransferase activity
ARA02_RS07485	COG1722	exodeoxyribonuclease VII activity
ARA02_RS07490	COG1570	exodeoxyribonuclease VII activity
ARA02_RS07505	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ARA02_RS07510	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ARA02_RS07515	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ARA02_RS07520	COG1121	(ABC) transporter
ARA02_RS07530	COG4466	Protein conserved in bacteria
ARA02_RS07535	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ARA02_RS07540	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
ARA02_RS07545	COG0084	hydrolase, TatD family'
ARA02_RS07550	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ARA02_RS07560	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ARA02_RS07570	COG1611	Belongs to the LOG family
ARA02_RS07575	COG5503	Protein of unknown function (DUF1447)
ARA02_RS07585	COG3152	Membrane
ARA02_RS07595	COG1892	Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four- carbon dicarboxylic acid source for the tricarboxylic acid cycle
ARA02_RS07610	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ARA02_RS07620	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ARA02_RS07625	COG0584	glycerophosphoryl diester phosphodiesterase
ARA02_RS07645	COG1393	Belongs to the ArsC family
ARA02_RS07675	COG1098	S1 RNA binding domain
ARA02_RS07685	COG1758	RNA polymerase activity
ARA02_RS07690	COG0194	GDP metabolic process
ARA02_RS07710	COG1193	negative regulation of DNA recombination
ARA02_RS07730	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ARA02_RS07745	COG1418	mRNA catabolic process
ARA02_RS07750	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ARA02_RS07755	COG0557	exoribonuclease II activity
ARA02_RS07765	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ARA02_RS07770	COG0706	membrane insertase activity
ARA02_RS07780	COG1254	Belongs to the acylphosphatase family
ARA02_RS07785	COG0745	RESPONSE REGULATOR receiver
ARA02_RS07795	COG1323	Belongs to the UPF0348 family
ARA02_RS07800	COG2226	methyltransferase
ARA02_RS07805	COG0799	negative regulation of ribosome biogenesis
ARA02_RS07810	COG1713	HD superfamily hydrolase involved in NAD metabolism
ARA02_RS07815	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ARA02_RS07820	COG1534	Rna-binding protein
ARA02_RS07825	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
ARA02_RS07830	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
ARA02_RS07855	COG1959	2 iron, 2 sulfur cluster binding
ARA02_RS07885	COG5263	repeat protein
ARA02_RS07885	COG0366	Alpha amylase catalytic
ARA02_RS07910	COG2323	membrane
ARA02_RS07930	COG0459	protein refolding
ARA02_RS07935	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ARA02_RS07950	COG3716	PTS system mannose fructose sorbose family IID component
ARA02_RS07955	COG3715	PTS system
ARA02_RS07965	COG1482	cell wall glycoprotein biosynthetic process
ARA02_RS07970	COG0778	Nitroreductase
ARA02_RS07980	COG0561	phosphatase activity
ARA02_RS07990	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
ARA02_RS07995	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ARA02_RS08010	COG1214	PFAM Peptidase M22, glycoprotease
ARA02_RS08025	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
ARA02_RS08030	COG0009	L-threonylcarbamoyladenylate synthase
ARA02_RS08035	COG2890	protein-(glutamine-N5) methyltransferase activity
ARA02_RS08045	COG1435	thymidine kinase activity
ARA02_RS08050	COG3883	PFAM NLP P60 protein
ARA02_RS08050	COG0791	NLP P60 protein
ARA02_RS08055	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ARA02_RS08060	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ARA02_RS08065	COG3442	glutamine amidotransferase
ARA02_RS08070	COG0531	amino acid
ARA02_RS08080	COG0628	permease
ARA02_RS08085	COG2040	homocysteine
ARA02_RS08090	COG0833	amino acid
ARA02_RS08095	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ARA02_RS08100	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ARA02_RS08105	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
ARA02_RS08115	COG2873	o-acetylhomoserine
ARA02_RS08120	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ARA02_RS08125	COG1854	S-ribosylhomocysteine lyase activity
ARA02_RS08130	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ARA02_RS08135	COG0626	cystathionine gamma-synthase activity
ARA02_RS08140	COG0626	cystathionine gamma-synthase activity
ARA02_RS08145	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
ARA02_RS08150	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ARA02_RS08155	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ARA02_RS08160	COG5002	protein histidine kinase activity
ARA02_RS08165	COG0745	RESPONSE REGULATOR receiver
ARA02_RS08170	COG2337	Toxic component of a toxin-antitoxin (TA) module
ARA02_RS08175	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ARA02_RS08180	COG0736	holo-[acyl-carrier-protein] synthase activity
ARA02_RS08185	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
ARA02_RS08190	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ARA02_RS08195	COG1696	Membrane protein involved in D-alanine export
ARA02_RS08200	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ARA02_RS08225	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ARA02_RS08230	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
ARA02_RS08235	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ARA02_RS08240	COG0085	RNA polymerase activity
ARA02_RS08305	COG0436	Aminotransferase
ARA02_RS08315	COG0531	amino acid
ARA02_RS08320	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
ARA02_RS08325	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ARA02_RS08335	COG2211	Major facilitator Superfamily
ARA02_RS08340	COG5506	Protein of unknown function (DUF1694)
ARA02_RS08345	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ARA02_RS08360	COG0833	amino acid
ARA02_RS08370	COG1316	TRANSCRIPTIONal
ARA02_RS08375	COG0531	amino acid
ARA02_RS08385	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ARA02_RS08400	COG0628	permease
ARA02_RS08405	COG1194	a g-specific adenine glycosylase
ARA02_RS08410	COG2814	Major facilitator Superfamily
ARA02_RS08415	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ARA02_RS08425	COG1902	pentaerythritol trinitrate reductase activity
ARA02_RS08430	COG1388	LysM domain
ARA02_RS08430	COG1705	Flagellar rod assembly protein muramidase FlgJ
ARA02_RS08435	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ARA02_RS08440	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ARA02_RS08445	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ARA02_RS08450	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ARA02_RS08455	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ARA02_RS08460	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ARA02_RS08465	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ARA02_RS08470	COG0356	it plays a direct role in the translocation of protons across the membrane
ARA02_RS08480	COG0588	phosphoglycerate mutase activity
ARA02_RS08485	COG1278	Cold shock
ARA02_RS08495	COG2814	Major facilitator Superfamily
ARA02_RS08505	COG3973	AAA domain
ARA02_RS08570	COG1511	domain protein
ARA02_RS08570	COG1511	domain protein
ARA02_RS08575	COG1309	transcriptional regulator
ARA02_RS08585	COG0697	spore germination
ARA02_RS08680	COG0488	(ABC) transporter
ARA02_RS08700	COG1064	alcohol dehydrogenase
ARA02_RS08705	COG2814	Major facilitator Superfamily
ARA02_RS08710	COG0126	phosphoglycerate kinase activity
ARA02_RS08740	COG3590	peptidase
ARA02_RS08745	COG4608	Belongs to the ABC transporter superfamily
ARA02_RS08750	COG0444	Belongs to the ABC transporter superfamily
ARA02_RS08755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ARA02_RS08765	COG4166	transmembrane transport
ARA02_RS08770	COG0765	amino acid transport
ARA02_RS08775	COG0765	amino acid transport
ARA02_RS08780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ARA02_RS08785	COG1126	abc transporter atp-binding protein
ARA02_RS08790	COG1132	(ABC) transporter
ARA02_RS08795	COG1132	(ABC) transporter
ARA02_RS08805	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ARA02_RS08810	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ARA02_RS08815	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ARA02_RS08820	COG1959	2 iron, 2 sulfur cluster binding
ARA02_RS08825	COG1511	domain protein
ARA02_RS08830	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ARA02_RS08835	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ARA02_RS08855	COG0745	RESPONSE REGULATOR receiver
ARA02_RS08860	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ARA02_RS08875	COG0473	3-isopropylmalate dehydrogenase activity
ARA02_RS08885	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ARA02_RS08890	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ARA02_RS08900	COG0028	Belongs to the TPP enzyme family
ARA02_RS08905	COG1119	ATPase activity
ARA02_RS08910	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
ARA02_RS08915	COG2188	Transcriptional regulator
ARA02_RS08920	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ARA02_RS08930	COG0305	Participates in initiation and elongation during chromosome replication
ARA02_RS08935	COG0359	binds to the 23S rRNA
ARA02_RS08945	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ARA02_RS08950	COG0629	single-stranded DNA binding
ARA02_RS08955	COG0360	Binds together with S18 to 16S ribosomal RNA
ARA02_RS08960	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ARA02_RS08975	COG4720	Psort location CytoplasmicMembrane, score
ARA02_RS08985	COG0514	ATP-dependent DNA helicase (RecQ)
ARA02_RS09045	COG0235	Class ii aldolase
ARA02_RS09050	COG3623	hexulose-6-phosphate isomerase
ARA02_RS09085	COG0561	phosphatase activity
ARA02_RS09110	COG2814	Major facilitator Superfamily
ARA02_RS09125	COG0583	DNA-binding transcription factor activity
ARA02_RS09130	COG1113	amino acid transport
ARA02_RS09135	COG1757	Na H antiporter
ARA02_RS09150	COG1733	regulation of RNA biosynthetic process
ARA02_RS09155	COG0667	Aldo Keto reductase
ARA02_RS09165	COG0667	Aldo Keto reductase
ARA02_RS09185	COG1686	Belongs to the peptidase S11 family
ARA02_RS09195	COG0803	Belongs to the bacterial solute-binding protein 9 family
ARA02_RS09200	COG2226	methyltransferase
ARA02_RS09205	COG0318	PFAM AMP-dependent synthetase and ligase
ARA02_RS09215	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
ARA02_RS09240	COG0477	Major facilitator Superfamily
ARA02_RS09245	COG0066	3-isopropylmalate dehydratase activity
ARA02_RS09250	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ARA02_RS09255	COG0473	3-isopropylmalate dehydrogenase activity
ARA02_RS09265	COG2151	metal-sulfur cluster biosynthetic enzyme
ARA02_RS09270	COG0719	Fe-S assembly protein
ARA02_RS09280	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ARA02_RS09285	COG0719	Fe-S assembly protein
ARA02_RS09290	COG0396	ATPase activity
ARA02_RS09300	COG0129	dihydroxy-acid dehydratase activity
ARA02_RS09305	COG2151	metal-sulfur cluster biosynthetic enzyme
ARA02_RS09320	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ARA02_RS09335	COG1983	PspC domain protein
ARA02_RS09350	COG0577	efflux transmembrane transporter activity
ARA02_RS09355	COG1136	(ABC) transporter
ARA02_RS09385	COG2855	membrane
ARA02_RS09390	COG0583	DNA-binding transcription factor activity
ARA02_RS09395	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ARA02_RS09415	COG0706	membrane insertase activity
ARA02_RS09420	COG0594	ribonuclease P activity
ARA02_RS09425	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ARA02_RS09430	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ARA02_RS09435	COG0446	pyridine nucleotide-disulphide oxidoreductase
ARA02_RS09445	COG2084	Dehydrogenase
ARA02_RS09475	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
ARA02_RS09490	COG0693	protein deglycase activity
ARA02_RS09495	COG1733	regulation of RNA biosynthetic process
ARA02_RS09505	COG0604	alcohol dehydrogenase
ARA02_RS09530	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ARA02_RS09545	COG1464	Belongs to the NlpA lipoprotein family
ARA02_RS09560	COG1573	uracil-dna glycosylase
ARA02_RS09565	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ARA02_RS09610	COG2801	Transposase and inactivated derivatives
ARA02_RS09630	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ARA02_RS09640	COG1609	Transcriptional regulator
ARA02_RS09665	COG1192	Involved in chromosome partitioning
ARA02_RS09775	COG1511	domain protein
ARA02_RS09775	COG1511	domain protein
ARA02_RS09820	COG1192	Involved in chromosome partitioning
ARA02_RS09920	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ARA02_RS09930	COG0492	ferredoxin-NADP+ reductase activity
ARA02_RS09940	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ARA02_RS09945	COG3118	belongs to the thioredoxin family
ARA02_RS09950	COG3118	belongs to the thioredoxin family
ARA02_RS09955	COG0640	Transcriptional regulator
ARA02_RS09965	COG2801	Transposase and inactivated derivatives