locus-tag	class	description
GJV51_RS00015	COG0165	Argininosuccinate lyase
GJV51_RS00020	COG0137	argininosuccinate synthase activity
GJV51_RS00025	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GJV51_RS00030	COG0217	transcriptional regulatory protein
GJV51_RS00040	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GJV51_RS00045	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GJV51_RS00060	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GJV51_RS00090	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GJV51_RS00095	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
GJV51_RS00095	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GJV51_RS00100	COG1234	tRNA 3'-trailer cleavage
GJV51_RS00105	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GJV51_RS00110	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GJV51_RS00115	COG0336	Belongs to the RNA methyltransferase TrmD family
GJV51_RS00120	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GJV51_RS00130	COG1074	ATP-dependent DNA helicase activity
GJV51_RS00135	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
GJV51_RS00150	COG0228	four-way junction DNA binding
GJV51_RS00160	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GJV51_RS00175	COG0762	integral membrane protein
GJV51_RS00180	COG1799	cell septum assembly
GJV51_RS00195	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GJV51_RS00200	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GJV51_RS00205	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GJV51_RS00210	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GJV51_RS00215	COG0768	penicillin binding
GJV51_RS00225	COG0275	rRNA processing
GJV51_RS00230	COG2001	Belongs to the MraZ family
GJV51_RS00245	COG1461	Dihydroxyacetone kinase
GJV51_RS00255	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GJV51_RS00260	COG3118	belongs to the thioredoxin family
GJV51_RS00270	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GJV51_RS00275	COG1162	GTPase activity
GJV51_RS00280	COG0515	serine threonine protein kinase
GJV51_RS00280	COG2815	serine threonine protein kinase
GJV51_RS00285	COG0631	protein serine/threonine phosphatase activity
GJV51_RS00290	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GJV51_RS00290	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GJV51_RS00295	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GJV51_RS00300	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GJV51_RS00315	COG3201	nicotinamide mononucleotide transporter
GJV51_RS00320	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GJV51_RS00325	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GJV51_RS00330	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GJV51_RS00335	COG0544	peptidyl-prolyl cis-trans isomerase activity
GJV51_RS00370	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GJV51_RS00375	COG0708	Exodeoxyribonuclease III
GJV51_RS00380	COG2176	DNA-directed DNA polymerase activity
GJV51_RS00390	COG0802	atpase or kinase
GJV51_RS00455	COG0438	transferase activity, transferring glycosyl groups
GJV51_RS00480	COG1073	alpha beta
GJV51_RS00495	COG0602	queuosine metabolic process
GJV51_RS00500	COG1328	CTP reductase activity
GJV51_RS00505	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GJV51_RS00510	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GJV51_RS00520	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GJV51_RS00530	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GJV51_RS00535	COG0107	imidazoleglycerol-phosphate synthase activity
GJV51_RS00540	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GJV51_RS00550	COG0131	Imidazoleglycerol-phosphate dehydratase
GJV51_RS00555	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GJV51_RS00565	COG2199	diguanylate cyclase activity
GJV51_RS00575	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GJV51_RS00580	COG0561	phosphatase activity
GJV51_RS00590	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GJV51_RS00600	COG0552	protein localization to endoplasmic reticulum
GJV51_RS00605	COG1196	nuclear chromosome segregation
GJV51_RS00610	COG0571	ribonuclease III activity
GJV51_RS00615	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GJV51_RS00635	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GJV51_RS00640	COG0105	UTP biosynthetic process
GJV51_RS00645	COG4807	Protein conserved in bacteria
GJV51_RS00670	COG3759	membrane
GJV51_RS00675	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GJV51_RS00680	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GJV51_RS00685	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GJV51_RS00690	COG1597	lipid kinase activity
GJV51_RS00695	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GJV51_RS00700	COG0154	amidase activity
GJV51_RS00705	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GJV51_RS00710	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GJV51_RS00715	COG0268	Binds directly to 16S ribosomal RNA
GJV51_RS00720	COG0513	Belongs to the DEAD box helicase family
GJV51_RS00725	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GJV51_RS00735	COG1466	dna polymerase III delta subunit
GJV51_RS00745	COG1596	polysaccharide export
GJV51_RS00745	COG1555	photosystem II stabilization
GJV51_RS00750	COG3480	Lon protease (S16) C-terminal proteolytic domain
GJV51_RS00755	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GJV51_RS00760	COG0742	ribosomal rna small subunit methyltransferase
GJV51_RS00765	COG4471	UPF0298 protein
GJV51_RS00770	COG0772	Belongs to the SEDS family
GJV51_RS00775	COG1363	Peptidase, m42
GJV51_RS00780	COG0588	phosphoglycerate mutase activity
GJV51_RS00785	COG0534	Mate efflux family protein
GJV51_RS00790	COG2252	PERMEase
GJV51_RS00795	COG0497	DNA recombination
GJV51_RS00800	COG1438	arginine binding
GJV51_RS00805	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
GJV51_RS00810	COG0142	geranyltranstransferase activity
GJV51_RS00815	COG1722	exodeoxyribonuclease VII activity
GJV51_RS00820	COG1570	exodeoxyribonuclease VII activity
GJV51_RS00835	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GJV51_RS00840	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GJV51_RS00845	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GJV51_RS00850	COG1121	(ABC) transporter
GJV51_RS00860	COG4466	Protein conserved in bacteria
GJV51_RS00865	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GJV51_RS00870	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GJV51_RS00875	COG0084	hydrolase, TatD family'
GJV51_RS00880	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GJV51_RS00890	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GJV51_RS00905	COG5503	Protein of unknown function (DUF1447)
GJV51_RS00915	COG3152	Membrane
GJV51_RS00925	COG1892	Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four- carbon dicarboxylic acid source for the tricarboxylic acid cycle
GJV51_RS00940	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GJV51_RS00950	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GJV51_RS00955	COG0584	glycerophosphoryl diester phosphodiesterase
GJV51_RS00970	COG4862	establishment of competence for transformation
GJV51_RS01005	COG1098	S1 RNA binding domain
GJV51_RS01015	COG1758	RNA polymerase activity
GJV51_RS01020	COG0194	GDP metabolic process
GJV51_RS01040	COG1193	negative regulation of DNA recombination
GJV51_RS01060	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GJV51_RS01075	COG1418	mRNA catabolic process
GJV51_RS01080	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GJV51_RS01085	COG0557	exoribonuclease II activity
GJV51_RS01095	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GJV51_RS01100	COG0706	membrane insertase activity
GJV51_RS01105	COG1254	Belongs to the acylphosphatase family
GJV51_RS01110	COG5002	protein histidine kinase activity
GJV51_RS01115	COG0745	RESPONSE REGULATOR receiver
GJV51_RS01125	COG1323	Belongs to the UPF0348 family
GJV51_RS01130	COG2226	methyltransferase
GJV51_RS01135	COG0799	negative regulation of ribosome biogenesis
GJV51_RS01140	COG1713	HD superfamily hydrolase involved in NAD metabolism
GJV51_RS01145	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GJV51_RS01150	COG1534	Rna-binding protein
GJV51_RS01155	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GJV51_RS01160	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
GJV51_RS01185	COG1959	2 iron, 2 sulfur cluster binding
GJV51_RS01190	COG0366	Alpha amylase catalytic
GJV51_RS01190	COG5263	repeat protein
GJV51_RS01215	COG0366	Alpha amylase catalytic
GJV51_RS01215	COG5263	repeat protein
GJV51_RS01245	COG2323	membrane
GJV51_RS01260	COG0459	protein refolding
GJV51_RS01265	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GJV51_RS01280	COG3716	PTS system mannose fructose sorbose family IID component
GJV51_RS01285	COG3715	PTS system
GJV51_RS01295	COG1482	cell wall glycoprotein biosynthetic process
GJV51_RS01300	COG0778	Nitroreductase
GJV51_RS01310	COG0561	phosphatase activity
GJV51_RS01320	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GJV51_RS01325	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GJV51_RS01340	COG1214	PFAM Peptidase M22, glycoprotease
GJV51_RS01345	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GJV51_RS01355	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GJV51_RS01360	COG0009	L-threonylcarbamoyladenylate synthase
GJV51_RS01365	COG2890	protein-(glutamine-N5) methyltransferase activity
GJV51_RS01370	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GJV51_RS01375	COG1435	thymidine kinase activity
GJV51_RS01380	COG3883	PFAM NLP P60 protein
GJV51_RS01380	COG0791	NLP P60 protein
GJV51_RS01385	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GJV51_RS01390	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GJV51_RS01395	COG3442	glutamine amidotransferase
GJV51_RS01400	COG0531	amino acid
GJV51_RS01410	COG0628	permease
GJV51_RS01415	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GJV51_RS01420	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GJV51_RS01425	COG2873	o-acetylhomoserine
GJV51_RS01430	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GJV51_RS01435	COG1854	S-ribosylhomocysteine lyase activity
GJV51_RS01440	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GJV51_RS01445	COG0626	cystathionine gamma-synthase activity
GJV51_RS01450	COG0626	cystathionine gamma-synthase activity
GJV51_RS01455	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
GJV51_RS01460	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GJV51_RS01465	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GJV51_RS01470	COG5002	protein histidine kinase activity
GJV51_RS01475	COG0745	RESPONSE REGULATOR receiver
GJV51_RS01480	COG2337	Toxic component of a toxin-antitoxin (TA) module
GJV51_RS01490	COG0736	holo-[acyl-carrier-protein] synthase activity
GJV51_RS01495	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GJV51_RS01500	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GJV51_RS01505	COG1696	Membrane protein involved in D-alanine export
GJV51_RS01510	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GJV51_RS01535	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GJV51_RS01540	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GJV51_RS01545	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GJV51_RS01550	COG0085	RNA polymerase activity
GJV51_RS01610	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GJV51_RS01615	COG0436	Aminotransferase
GJV51_RS01620	COG0194	GDP metabolic process
GJV51_RS01625	COG0531	amino acid
GJV51_RS01630	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
GJV51_RS01635	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GJV51_RS01640	COG5506	Protein of unknown function (DUF1694)
GJV51_RS01645	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GJV51_RS01660	COG0833	amino acid
GJV51_RS01670	COG1316	TRANSCRIPTIONal
GJV51_RS01675	COG0531	amino acid
GJV51_RS01685	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GJV51_RS01700	COG0628	permease
GJV51_RS01705	COG1194	a g-specific adenine glycosylase
GJV51_RS01710	COG2814	Major facilitator Superfamily
GJV51_RS01715	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GJV51_RS01725	COG1902	pentaerythritol trinitrate reductase activity
GJV51_RS01730	COG1705	Flagellar rod assembly protein muramidase FlgJ
GJV51_RS01730	COG1388	LysM domain
GJV51_RS01735	COG0737	Belongs to the 5'-nucleotidase family
GJV51_RS01740	COG3639	organic phosphonate transmembrane transporter activity
GJV51_RS01750	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
GJV51_RS01760	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GJV51_RS01765	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GJV51_RS01770	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GJV51_RS01775	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GJV51_RS01780	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GJV51_RS01785	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GJV51_RS01790	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GJV51_RS01795	COG0356	it plays a direct role in the translocation of protons across the membrane
GJV51_RS01805	COG0588	phosphoglycerate mutase activity
GJV51_RS01810	COG1278	Cold shock
GJV51_RS01820	COG2814	Major facilitator Superfamily
GJV51_RS01825	COG1072	(Pantothenic acid kinase))
GJV51_RS01830	COG3973	AAA domain
GJV51_RS01875	COG1511	domain protein
GJV51_RS01880	COG1309	transcriptional regulator
GJV51_RS01925	COG2720	vancomycin resistance protein
GJV51_RS01975	COG2246	polysaccharide biosynthetic process
GJV51_RS01995	COG0488	(ABC) transporter
GJV51_RS02005	COG1064	alcohol dehydrogenase
GJV51_RS02010	COG2814	Major facilitator Superfamily
GJV51_RS02015	COG0126	phosphoglycerate kinase activity
GJV51_RS02045	COG3590	peptidase
GJV51_RS02050	COG4608	Belongs to the ABC transporter superfamily
GJV51_RS02055	COG0444	Belongs to the ABC transporter superfamily
GJV51_RS02060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GJV51_RS02065	COG0601	transmembrane transport
GJV51_RS02070	COG4166	transmembrane transport
GJV51_RS02075	COG0765	amino acid transport
GJV51_RS02080	COG0765	amino acid transport
GJV51_RS02085	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GJV51_RS02090	COG1126	abc transporter atp-binding protein
GJV51_RS02095	COG1132	(ABC) transporter
GJV51_RS02100	COG1132	(ABC) transporter
GJV51_RS02110	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GJV51_RS02115	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GJV51_RS02120	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GJV51_RS02125	COG1959	2 iron, 2 sulfur cluster binding
GJV51_RS02130	COG1511	domain protein
GJV51_RS02135	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GJV51_RS02140	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GJV51_RS02160	COG0745	RESPONSE REGULATOR receiver
GJV51_RS02165	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GJV51_RS02185	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
GJV51_RS02190	COG2188	Transcriptional regulator
GJV51_RS02195	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GJV51_RS02205	COG0305	Participates in initiation and elongation during chromosome replication
GJV51_RS02210	COG0359	binds to the 23S rRNA
GJV51_RS02220	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GJV51_RS02225	COG0629	single-stranded DNA binding
GJV51_RS02230	COG0360	Binds together with S18 to 16S ribosomal RNA
GJV51_RS02235	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GJV51_RS02245	COG1122	ATPase activity
GJV51_RS02250	COG4720	Psort location CytoplasmicMembrane, score
GJV51_RS02260	COG0514	ATP-dependent DNA helicase (RecQ)
GJV51_RS02295	COG1757	Na H antiporter
GJV51_RS02305	COG1122	ATPase activity
GJV51_RS02320	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
GJV51_RS02330	COG2814	Major facilitator Superfamily
GJV51_RS02345	COG0803	Belongs to the bacterial solute-binding protein 9 family
GJV51_RS02350	COG2226	methyltransferase
GJV51_RS02365	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
GJV51_RS02390	COG0066	3-isopropylmalate dehydratase activity
GJV51_RS02395	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GJV51_RS02400	COG0473	3-isopropylmalate dehydrogenase activity
GJV51_RS02405	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GJV51_RS02410	COG2151	metal-sulfur cluster biosynthetic enzyme
GJV51_RS02415	COG0702	epimerase
GJV51_RS02420	COG0719	Fe-S assembly protein
GJV51_RS02430	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GJV51_RS02435	COG0719	Fe-S assembly protein
GJV51_RS02440	COG0396	ATPase activity
GJV51_RS02455	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GJV51_RS02470	COG1983	PspC domain protein
GJV51_RS02485	COG0577	efflux transmembrane transporter activity
GJV51_RS02490	COG1136	(ABC) transporter
GJV51_RS02520	COG2855	membrane
GJV51_RS02525	COG0583	DNA-binding transcription factor activity
GJV51_RS02530	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GJV51_RS02550	COG0706	membrane insertase activity
GJV51_RS02555	COG0594	ribonuclease P activity
GJV51_RS02560	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GJV51_RS02565	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GJV51_RS02570	COG0446	pyridine nucleotide-disulphide oxidoreductase
GJV51_RS02580	COG2084	Dehydrogenase
GJV51_RS02585	COG0561	phosphatase activity
GJV51_RS02605	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GJV51_RS02610	COG0592	DNA-directed DNA polymerase activity
GJV51_RS02620	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GJV51_RS02625	COG0187	DNA topoisomerase II activity
GJV51_RS02635	COG0386	Belongs to the glutathione peroxidase family
GJV51_RS02645	COG1073	alpha beta
GJV51_RS02660	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GJV51_RS02665	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GJV51_RS02670	COG0436	Aminotransferase
GJV51_RS02770	COG2814	Major facilitator Superfamily
GJV51_RS02775	COG0647	UMP catabolic process
GJV51_RS02795	COG1368	sulfuric ester hydrolase activity
GJV51_RS02800	COG0438	transferase activity, transferring glycosyl groups
GJV51_RS02810	COG0564	pseudouridine synthase activity
GJV51_RS02815	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GJV51_RS02820	COG2217	Heavy metal translocating P-type atpase
GJV51_RS02830	COG1725	Transcriptional regulator
GJV51_RS02835	COG1131	(ABC) transporter
GJV51_RS02845	COG1131	(ABC) transporter
GJV51_RS02855	COG0656	L-ascorbic acid biosynthetic process
GJV51_RS02865	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GJV51_RS02870	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GJV51_RS02875	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
GJV51_RS02880	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GJV51_RS02885	COG1881	PFAM PEBP family protein
GJV51_RS02900	COG0569	domain protein
GJV51_RS02905	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GJV51_RS02935	COG3845	ABC transporter
GJV51_RS02940	COG4603	Belongs to the binding-protein-dependent transport system permease family
GJV51_RS02945	COG1079	Belongs to the binding-protein-dependent transport system permease family
GJV51_RS02960	COG4120	Belongs to the binding-protein-dependent transport system permease family
GJV51_RS03040	COG0446	pyridine nucleotide-disulphide oxidoreductase
GJV51_RS03050	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
GJV51_RS03055	COG1464	Belongs to the NlpA lipoprotein family
GJV51_RS03070	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GJV51_RS03075	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GJV51_RS03080	COG1307	EDD domain protein, DegV family
GJV51_RS03085	COG1272	protein, Hemolysin III
GJV51_RS03095	COG1968	undecaprenyl-diphosphatase activity
GJV51_RS03110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GJV51_RS03115	COG0765	amino acid transport
GJV51_RS03120	COG0765	amino acid transport
GJV51_RS03125	COG1126	abc transporter atp-binding protein
GJV51_RS03130	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GJV51_RS03140	COG4720	Psort location CytoplasmicMembrane, score
GJV51_RS03145	COG0351	phosphomethylpyrimidine kinase
GJV51_RS03160	COG1012	belongs to the aldehyde dehydrogenase family
GJV51_RS03160	COG1454	alcohol dehydrogenase
GJV51_RS03165	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GJV51_RS03200	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GJV51_RS03210	COG0756	dUTP diphosphatase activity
GJV51_RS03230	COG1309	transcriptional regulator
GJV51_RS03235	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GJV51_RS03240	COG0215	cysteine-tRNA ligase activity
GJV51_RS03340	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GJV51_RS03345	COG0653	protein targeting
GJV51_RS03350	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GJV51_RS03355	COG0542	response to heat
GJV51_RS03360	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
GJV51_RS03365	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GJV51_RS03370	COG0049	tRNA binding
GJV51_RS03375	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GJV51_RS03385	COG3842	ATPase activity
GJV51_RS03395	COG1177	transmembrane transport
GJV51_RS03405	COG0051	transcription antitermination factor activity, RNA binding
GJV51_RS03410	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GJV51_RS03415	COG0088	Forms part of the polypeptide exit tunnel
GJV51_RS03420	COG0089	rRNA binding
GJV51_RS03425	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GJV51_RS03430	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GJV51_RS03435	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GJV51_RS03440	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GJV51_RS03445	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GJV51_RS03450	COG0255	Belongs to the universal ribosomal protein uL29 family
GJV51_RS03455	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GJV51_RS03460	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GJV51_RS03465	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GJV51_RS03470	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GJV51_RS03475	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GJV51_RS03480	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GJV51_RS03485	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GJV51_RS03490	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GJV51_RS03495	COG1841	ribosomal large subunit assembly
GJV51_RS03500	COG0200	Binds to the 23S rRNA
GJV51_RS03510	COG0563	adenylate kinase activity
GJV51_RS03515	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GJV51_RS03520	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GJV51_RS03525	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GJV51_RS03530	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GJV51_RS03535	COG0202	RNA polymerase activity
GJV51_RS03540	COG0203	ribosomal protein L17
GJV51_RS03545	COG0142	geranyltranstransferase activity
GJV51_RS03555	COG1122	ATPase activity
GJV51_RS03560	COG1122	ATPase activity
GJV51_RS03565	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GJV51_RS03570	COG0101	tRNA pseudouridine synthase activity
GJV51_RS03580	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GJV51_RS03585	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GJV51_RS03620	COG0149	triose-phosphate isomerase activity
GJV51_RS03625	COG0148	phosphopyruvate hydratase activity
GJV51_RS03640	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GJV51_RS03645	COG0248	Ppx GppA phosphatase
GJV51_RS03650	COG1739	Uncharacterized protein family UPF0029
GJV51_RS03655	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
GJV51_RS03660	COG1040	competence protein
GJV51_RS03675	COG0588	phosphoglycerate mutase activity
GJV51_RS03680	COG1253	flavin adenine dinucleotide binding
GJV51_RS03685	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GJV51_RS03690	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GJV51_RS03695	COG1780	Probably involved in ribonucleotide reductase function
GJV51_RS03710	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GJV51_RS03725	COG1077	Cell shape determining protein MreB Mrl
GJV51_RS03735	COG0772	Belongs to the SEDS family
GJV51_RS03745	COG1181	Belongs to the D-alanine--D-alanine ligase family
GJV51_RS03755	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GJV51_RS03770	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GJV51_RS03775	COG0081	regulation of translation
GJV51_RS03780	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GJV51_RS03785	COG0222	ribosome binding
GJV51_RS03790	COG2813	Specifically methylates the guanine in position
GJV51_RS03795	COG0590	tRNA wobble adenosine to inosine editing
GJV51_RS03810	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GJV51_RS03815	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GJV51_RS03825	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GJV51_RS03830	COG3870	Protein conserved in bacteria
GJV51_RS03835	COG0470	DNA polymerase III
GJV51_RS03850	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GJV51_RS03855	COG1609	Transcriptional regulator
GJV51_RS03865	COG1621	beta-fructofuranosidase activity
GJV51_RS03870	COG1940	carbohydrate kinase activity
GJV51_RS03885	COG1428	Deoxynucleoside kinase
GJV51_RS03890	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GJV51_RS03895	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GJV51_RS03905	COG0492	ferredoxin-NADP+ reductase activity
GJV51_RS03915	COG1418	mRNA catabolic process
GJV51_RS03920	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GJV51_RS03920	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GJV51_RS03935	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GJV51_RS03945	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GJV51_RS03950	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GJV51_RS03960	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GJV51_RS03970	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GJV51_RS03985	COG0439	Biotin carboxylase
GJV51_RS03990	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GJV51_RS04010	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GJV51_RS04015	COG1573	uracil-dna glycosylase
GJV51_RS04020	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
GJV51_RS04035	COG3340	Belongs to the peptidase S51 family
GJV51_RS04040	COG0525	valine-tRNA ligase activity
GJV51_RS04045	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GJV51_RS04060	COG3103	Sh3 type 3 domain protein
GJV51_RS04060	COG0791	NLP P60 protein
GJV51_RS04060	COG1388	LysM domain
GJV51_RS04070	COG0768	penicillin binding
GJV51_RS04075	COG0640	Transcriptional regulator
GJV51_RS04085	COG1136	(ABC) transporter
GJV51_RS04085	COG0577	efflux transmembrane transporter activity
GJV51_RS04090	COG1316	TRANSCRIPTIONal
GJV51_RS04115	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GJV51_RS04125	COG1914	H( )-stimulated, divalent metal cation uptake system
GJV51_RS04135	COG0640	Transcriptional regulator
GJV51_RS04145	COG1957	nucleoside hydrolase
GJV51_RS04150	COG0357	Ribosomal RNA small subunit methyltransferase G
GJV51_RS04155	COG1192	Involved in chromosome partitioning
GJV51_RS04160	COG1475	DNA binding
GJV51_RS04165	COG4481	Protein conserved in bacteria
GJV51_RS04170	COG0012	GTP binding
GJV51_RS04180	COG0745	RESPONSE REGULATOR receiver
GJV51_RS04185	COG2205	protein histidine kinase activity
GJV51_RS04195	COG0363	glucosamine-6-phosphate deaminase activity
GJV51_RS04200	COG0166	Belongs to the GPI family
GJV51_RS04210	COG3448	diguanylate cyclase activity
GJV51_RS04210	COG4175	Glycine betaine
GJV51_RS04230	COG4152	abc transporter atp-binding protein
GJV51_RS04355	COG4974	Belongs to the 'phage' integrase family
GJV51_RS04360	COG0343	queuine tRNA-ribosyltransferase activity
GJV51_RS04365	COG1862	Preprotein translocase
GJV51_RS04375	COG0392	lysyltransferase activity
GJV51_RS04375	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GJV51_RS04390	COG0406	alpha-ribazole phosphatase activity
GJV51_RS04405	COG1132	(ABC) transporter
GJV51_RS04410	COG1132	(ABC) transporter
GJV51_RS04415	COG0438	transferase activity, transferring glycosyl groups
GJV51_RS04435	COG1368	sulfuric ester hydrolase activity
GJV51_RS04440	COG0556	nucleotide-excision repair
GJV51_RS04445	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GJV51_RS04450	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GJV51_RS04455	COG1481	regulation of sporulation
GJV51_RS04460	COG0740	serine-type endopeptidase activity
GJV51_RS04470	COG0193	aminoacyl-tRNA hydrolase activity
GJV51_RS04475	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GJV51_RS04480	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GJV51_RS04490	COG0037	tRNA processing
GJV51_RS04500	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GJV51_RS04505	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GJV51_RS04510	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GJV51_RS04535	COG0217	transcriptional regulatory protein
GJV51_RS04545	COG2252	PERMEase
GJV51_RS04550	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GJV51_RS04575	COG0477	Major facilitator Superfamily
GJV51_RS04595	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GJV51_RS04605	COG2188	Transcriptional regulator
GJV51_RS04615	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GJV51_RS04625	COG1464	Belongs to the NlpA lipoprotein family
GJV51_RS04660	COG1744	ABC transporter substrate-binding protein PnrA-like
GJV51_RS04665	COG0765	amino acid transport
GJV51_RS04670	COG1126	abc transporter atp-binding protein
GJV51_RS04675	COG0765	amino acid transport
GJV51_RS04700	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GJV51_RS04705	COG1733	regulation of RNA biosynthetic process
GJV51_RS04710	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GJV51_RS04715	COG0072	phenylalanine-tRNA ligase activity
GJV51_RS04715	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GJV51_RS04720	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GJV51_RS04725	COG0254	rRNA binding
GJV51_RS04730	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GJV51_RS04735	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GJV51_RS04740	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GJV51_RS04755	COG2814	Major facilitator Superfamily
GJV51_RS04760	COG2003	Belongs to the UPF0758 family
GJV51_RS04765	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GJV51_RS04770	COG2131	deaminase
GJV51_RS04775	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GJV51_RS04780	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GJV51_RS04790	COG4537	Required for transformation and DNA binding
GJV51_RS04820	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GJV51_RS04825	COG1705	Flagellar rod assembly protein muramidase FlgJ
GJV51_RS04830	COG4975	Glucose uptake
GJV51_RS04835	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GJV51_RS04875	COG0559	Belongs to the binding-protein-dependent transport system permease family
GJV51_RS04885	COG0411	ABC transporter
GJV51_RS04895	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
GJV51_RS04900	COG0351	phosphomethylpyrimidine kinase
GJV51_RS04905	COG0352	thiamine-phosphate diphosphorylase activity
GJV51_RS04910	COG1012	belongs to the aldehyde dehydrogenase family
GJV51_RS04945	COG4493	Belongs to the UPF0637 family
GJV51_RS04950	COG0025	NhaP-type Na H and K H
GJV51_RS04955	COG1609	Transcriptional regulator
GJV51_RS04975	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GJV51_RS04985	COG0308	aminopeptidase N
GJV51_RS04995	COG2936	dipeptidyl-peptidase activity
GJV51_RS05000	COG2190	(PTS) system
GJV51_RS05005	COG2190	(PTS) system
GJV51_RS05005	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GJV51_RS05005	COG1263	PTS System
GJV51_RS05010	COG0366	Alpha amylase catalytic
GJV51_RS05015	COG2188	Transcriptional regulator
GJV51_RS05020	COG1078	dGTPase activity
GJV51_RS05030	COG3343	RNA polymerase activity
GJV51_RS05040	COG1113	amino acid transport
GJV51_RS05045	COG1268	BioY protein
GJV51_RS05055	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
GJV51_RS05055	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
GJV51_RS05060	COG0504	CTP synthase activity
GJV51_RS05065	COG0322	excinuclease ABC activity
GJV51_RS05070	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GJV51_RS05075	COG0028	Belongs to the TPP enzyme family
GJV51_RS05080	COG2309	aminopeptidase activity
GJV51_RS05090	COG0673	inositol 2-dehydrogenase activity
GJV51_RS05095	COG0513	Belongs to the DEAD box helicase family
GJV51_RS05100	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GJV51_RS05110	COG0237	dephospho-CoA kinase activity
GJV51_RS05120	COG1484	DNA-dependent DNA replication
GJV51_RS05145	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GJV51_RS05150	COG0416	fatty acid biosynthetic process
GJV51_RS05155	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GJV51_RS05160	COG3091	SprT-like family
GJV51_RS05165	COG0561	phosphatase activity
GJV51_RS05185	COG1609	Transcriptional regulator
GJV51_RS05190	COG2755	lipolytic protein G-D-S-L family
GJV51_RS05190	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GJV51_RS05195	COG2814	Major facilitator Superfamily
GJV51_RS05205	COG0697	spore germination
GJV51_RS05210	COG3527	Alpha-acetolactate decarboxylase
GJV51_RS05215	COG1737	Transcriptional regulator
GJV51_RS05220	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
GJV51_RS05235	COG0531	amino acid
GJV51_RS05245	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GJV51_RS05250	COG4472	Bacterial protein of unknown function (DUF965)
GJV51_RS05255	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GJV51_RS05260	COG3906	Belongs to the UPF0473 family
GJV51_RS05265	COG1271	oxidase subunit
GJV51_RS05270	COG1294	oxidase, subunit
GJV51_RS05275	COG4988	ABC transporter
GJV51_RS05280	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GJV51_RS05285	COG1705	Flagellar rod assembly protein muramidase FlgJ
GJV51_RS05290	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GJV51_RS05305	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GJV51_RS05310	COG4851	CamS sex pheromone cAM373 precursor
GJV51_RS05320	COG0542	response to heat
GJV51_RS05325	COG1077	Cell shape determining protein MreB Mrl
GJV51_RS05340	COG0765	amino acid transport
GJV51_RS05350	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GJV51_RS05360	COG0612	Peptidase, M16
GJV51_RS05365	COG0612	Peptidase, M16
GJV51_RS05370	COG1426	Protein conserved in bacteria
GJV51_RS05375	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GJV51_RS05380	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GJV51_RS05385	COG0745	RESPONSE REGULATOR receiver
GJV51_RS05405	COG0573	inorganic phosphate transmembrane transporter activity
GJV51_RS05410	COG0581	inorganic phosphate transmembrane transporter activity
GJV51_RS05415	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GJV51_RS05420	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GJV51_RS05425	COG0704	Plays a role in the regulation of phosphate uptake
GJV51_RS05435	COG1950	PFAM Membrane protein of
GJV51_RS05440	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GJV51_RS05445	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GJV51_RS05450	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GJV51_RS05455	COG0492	ferredoxin-NADP+ reductase activity
GJV51_RS05470	COG1063	alcohol dehydrogenase
GJV51_RS05475	COG1609	Transcriptional regulator
GJV51_RS05485	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GJV51_RS05490	COG0335	large ribosomal subunit rRNA binding
GJV51_RS05495	COG1719	4-vinyl reductase, 4VR
GJV51_RS05505	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GJV51_RS05515	COG2255	four-way junction helicase activity
GJV51_RS05525	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GJV51_RS05530	COG0584	glycerophosphoryl diester phosphodiesterase
GJV51_RS05535	COG0632	four-way junction helicase activity
GJV51_RS05540	COG1428	Deoxynucleoside kinase
GJV51_RS05545	COG1970	mechanosensitive ion channel activity
GJV51_RS05550	COG4684	Psort location CytoplasmicMembrane, score
GJV51_RS05560	COG4684	Psort location CytoplasmicMembrane, score
GJV51_RS05580	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GJV51_RS05585	COG1126	abc transporter atp-binding protein
GJV51_RS05590	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GJV51_RS05600	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GJV51_RS05610	COG0671	phosphoesterase, PA-phosphatase related
GJV51_RS05615	COG0495	leucyl-tRNA aminoacylation
GJV51_RS05620	COG2244	polysaccharide biosynthetic process
GJV51_RS05635	COG1704	LemA family
GJV51_RS05640	COG0501	Belongs to the peptidase M48B family
GJV51_RS05645	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GJV51_RS05650	COG1942	4-Oxalocrotonate Tautomerase
GJV51_RS05665	COG0517	IMP dehydrogenase activity
GJV51_RS05665	COG0516	GMP reductase activity
GJV51_RS05670	COG0516	GMP reductase activity
GJV51_RS05670	COG0517	IMP dehydrogenase activity
GJV51_RS05720	COG1674	ftsk spoiiie
GJV51_RS05750	COG3331	DNA recombination
GJV51_RS05760	COG4474	Belongs to the UPF0398 family
GJV51_RS05765	COG3599	regulation of cell shape
GJV51_RS05775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GJV51_RS05780	COG2706	6-phosphogluconolactonase activity
GJV51_RS05785	COG0628	permease
GJV51_RS05790	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GJV51_RS05800	COG1674	ftsk spoiiie
GJV51_RS05805	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GJV51_RS05810	COG1113	amino acid transport
GJV51_RS05815	COG0586	Pfam SNARE associated Golgi protein
GJV51_RS05825	COG3001	Fructosamine kinase
GJV51_RS05835	COG2171	N-acyltransferase activity
GJV51_RS05840	COG1473	amidohydrolase
GJV51_RS05845	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GJV51_RS05850	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GJV51_RS05855	COG2137	regulation of response to DNA damage stimulus
GJV51_RS05860	COG3557	Belongs to the UPF0374 family
GJV51_RS05865	COG0705	Rhomboid family
GJV51_RS05875	COG1940	carbohydrate kinase activity
GJV51_RS05885	COG2357	RelA SpoT domain protein
GJV51_RS05890	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GJV51_RS05895	COG0564	pseudouridine synthase activity
GJV51_RS05900	COG2239	Acts as a magnesium transporter
GJV51_RS05910	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GJV51_RS05915	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GJV51_RS05920	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GJV51_RS05925	COG4589	Belongs to the CDS family
GJV51_RS05930	COG0750	zinc metalloprotease
GJV51_RS05935	COG0442	prolyl-tRNA aminoacylation
GJV51_RS05940	COG2176	DNA-directed DNA polymerase activity
GJV51_RS05955	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GJV51_RS05955	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
GJV51_RS05960	COG1744	ABC transporter substrate-binding protein PnrA-like
GJV51_RS05975	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GJV51_RS05980	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GJV51_RS05990	COG0667	Aldo Keto reductase
GJV51_RS05995	COG0151	Belongs to the GarS family
GJV51_RS06000	COG2759	Belongs to the formate--tetrahydrofolate ligase family
GJV51_RS06005	COG1278	Cold shock
GJV51_RS06010	COG0494	nUDIX hydrolase
GJV51_RS06020	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GJV51_RS06025	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GJV51_RS06030	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GJV51_RS06050	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GJV51_RS06050	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GJV51_RS06055	COG3764	Sortase (surface protein transpeptidase)
GJV51_RS06065	COG0789	Transcriptional regulator
GJV51_RS06070	COG0174	glutamine synthetase
GJV51_RS06075	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GJV51_RS06080	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GJV51_RS06085	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GJV51_RS06090	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GJV51_RS06100	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GJV51_RS06110	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GJV51_RS06115	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GJV51_RS06120	COG0138	bifunctional purine biosynthesis protein purh
GJV51_RS06125	COG0420	3'-5' exonuclease activity
GJV51_RS06130	COG4717	serine-type aminopeptidase activity
GJV51_RS06150	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GJV51_RS06160	COG0095	Lipoate-protein ligase
GJV51_RS06185	COG2267	carboxylic ester hydrolase activity
GJV51_RS06190	COG0584	glycerophosphoryl diester phosphodiesterase
GJV51_RS06210	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GJV51_RS06215	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GJV51_RS06225	COG0351	phosphomethylpyrimidine kinase
GJV51_RS06230	COG1169	isochorismate synthase
GJV51_RS06235	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GJV51_RS06245	COG4948	Mandelate Racemase Muconate Lactonizing
GJV51_RS06255	COG0617	tRNA 3'-terminal CCA addition
GJV51_RS06265	COG1307	EDD domain protein, DegV family
GJV51_RS06280	COG2755	lipolytic protein G-D-S-L family
GJV51_RS06290	COG4479	Belongs to the UPF0346 family
GJV51_RS06295	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GJV51_RS06300	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GJV51_RS06310	COG1122	ATPase activity
GJV51_RS06325	COG2384	SAM-dependent methyltransferase
GJV51_RS06330	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GJV51_RS06345	COG0587	DNA-directed DNA polymerase activity
GJV51_RS06355	COG0004	ammonium transporteR
GJV51_RS06360	COG1702	phosphate starvation-inducible protein PhoH
GJV51_RS06365	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GJV51_RS06375	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GJV51_RS06380	COG1381	Involved in DNA repair and RecF pathway recombination
GJV51_RS06385	COG0252	asparaginase activity
GJV51_RS06395	COG0527	aspartate kinase activity
GJV51_RS06400	COG0083	homoserine kinase activity
GJV51_RS06405	COG0460	homoserine dehydrogenase
GJV51_RS06410	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GJV51_RS06415	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GJV51_RS06420	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GJV51_RS06435	COG1609	Transcriptional regulator
GJV51_RS06440	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GJV51_RS06455	COG0517	IMP dehydrogenase activity
GJV51_RS06455	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GJV51_RS06460	COG2877	3-deoxy-8-phosphooctulonate synthase activity
GJV51_RS06475	COG1136	(ABC) transporter
GJV51_RS06480	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GJV51_RS06500	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GJV51_RS06505	COG0415	Belongs to the DNA photolyase family
GJV51_RS06510	COG0577	efflux transmembrane transporter activity
GJV51_RS06530	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GJV51_RS06545	COG1609	Transcriptional regulator
GJV51_RS06550	COG0745	RESPONSE REGULATOR receiver
GJV51_RS06555	COG5002	protein histidine kinase activity
GJV51_RS06560	COG1136	(ABC) transporter
GJV51_RS06570	COG0667	Aldo Keto reductase
GJV51_RS06585	COG1028	Short-chain dehydrogenase reductase Sdr
GJV51_RS06600	COG2261	transglycosylase associated protein
GJV51_RS06620	COG2261	transglycosylase associated protein
GJV51_RS06630	COG2814	Major facilitator Superfamily
GJV51_RS06635	COG5039	Polysaccharide pyruvyl transferase
GJV51_RS06640	COG1472	Belongs to the glycosyl hydrolase 3 family
GJV51_RS06675	COG0366	Alpha amylase catalytic
GJV51_RS06685	COG0366	Alpha amylase catalytic
GJV51_RS06690	COG3711	transcriptional antiterminator
GJV51_RS06695	COG1263	PTS System
GJV51_RS06695	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GJV51_RS06695	COG2190	(PTS) system
GJV51_RS06700	COG2723	6-phospho-beta-galactosidase activity
GJV51_RS06705	COG1956	GAF domain-containing protein
GJV51_RS06710	COG2244	polysaccharide biosynthetic process
GJV51_RS06715	COG1609	Transcriptional regulator
GJV51_RS06730	COG0366	Alpha amylase catalytic
GJV51_RS06760	COG0300	oxidoreductase activity
GJV51_RS06765	COG1063	alcohol dehydrogenase
GJV51_RS06775	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GJV51_RS06780	COG1619	proteins homologs of microcin C7 resistance protein MccF
GJV51_RS06790	COG2723	6-phospho-beta-galactosidase activity
GJV51_RS06805	COG1447	Phosphotransferase system cellobiose-specific component IIA
GJV51_RS06815	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GJV51_RS06835	COG1028	Short-chain dehydrogenase reductase Sdr
GJV51_RS06850	COG1846	Transcriptional regulator
GJV51_RS06860	COG0604	alcohol dehydrogenase
GJV51_RS06865	COG1442	glycosyl transferase family 8
GJV51_RS06870	COG1121	(ABC) transporter
GJV51_RS06875	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GJV51_RS06890	COG1316	TRANSCRIPTIONal
GJV51_RS06895	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GJV51_RS06905	COG2364	Membrane
GJV51_RS06920	COG0534	Mate efflux family protein
GJV51_RS06945	COG1122	ATPase activity
GJV51_RS06955	COG0789	Transcriptional regulator
GJV51_RS06990	COG0702	epimerase
GJV51_RS07025	COG1233	COG1233 Phytoene dehydrogenase and related
GJV51_RS07030	COG1562	ergosterol biosynthetic process
GJV51_RS07035	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GJV51_RS07040	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GJV51_RS07045	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GJV51_RS07055	COG1476	TRANSCRIPTIONal
GJV51_RS07070	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GJV51_RS07095	COG1136	(ABC) transporter
GJV51_RS07095	COG0577	efflux transmembrane transporter activity
GJV51_RS07120	COG0384	phenazine biosynthesis protein PhzF
GJV51_RS07125	COG2814	Major facilitator Superfamily
GJV51_RS07145	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GJV51_RS07150	COG1309	transcriptional regulator
GJV51_RS07175	COG0667	Aldo Keto reductase
GJV51_RS07355	COG0433	COG0433 Predicted ATPase
GJV51_RS07380	COG1674	ftsk spoiiie
GJV51_RS07420	COG2826	transposase and inactivated derivatives, IS30 family
GJV51_RS07430	COG1611	Belongs to the LOG family
GJV51_RS07505	COG0433	COG0433 Predicted ATPase
GJV51_RS07530	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GJV51_RS07620	COG0542	response to heat
GJV51_RS07645	COG1192	Involved in chromosome partitioning
GJV51_RS07710	COG2826	transposase and inactivated derivatives, IS30 family
GJV51_RS07730	COG1028	Short-chain dehydrogenase reductase Sdr
GJV51_RS07735	COG0710	3-dehydroquinate dehydratase activity
GJV51_RS07745	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GJV51_RS07750	COG0287	Prephenate dehydrogenase
GJV51_RS07755	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GJV51_RS07760	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GJV51_RS07765	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GJV51_RS07770	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
GJV51_RS07780	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GJV51_RS07785	COG0512	Glutamine amidotransferase of anthranilate synthase
GJV51_RS07790	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GJV51_RS07795	COG0159	tryptophan synthase activity
GJV51_RS07805	COG0134	indole-3-glycerol-phosphate synthase activity
GJV51_RS07810	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GJV51_RS07835	COG2848	UPF0210 protein
GJV51_RS07840	COG3830	Belongs to the UPF0237 family
GJV51_RS07855	COG3425	synthase
GJV51_RS07860	COG0488	(ABC) transporter
GJV51_RS07870	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GJV51_RS07875	COG2264	protein methyltransferase activity
GJV51_RS07880	COG0604	alcohol dehydrogenase
GJV51_RS07895	COG0673	inositol 2-dehydrogenase activity
GJV51_RS07900	COG0751	glycine-tRNA ligase activity
GJV51_RS07905	COG0752	glycyl-tRNA synthetase alpha subunit
GJV51_RS07910	COG0233	cytoplasmic translational termination
GJV51_RS07915	COG0528	UMP kinase activity
GJV51_RS07920	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GJV51_RS07925	COG0052	Belongs to the universal ribosomal protein uS2 family
GJV51_RS07930	COG2827	Endonuclease containing a URI domain
GJV51_RS07935	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GJV51_RS07940	COG0204	Acyl-transferase
GJV51_RS07945	COG3763	UPF0154 protein
GJV51_RS07950	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GJV51_RS07960	COG0284	orotidine-5'-phosphate decarboxylase activity
GJV51_RS07965	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GJV51_RS07970	COG0505	Belongs to the CarA family
GJV51_RS07975	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GJV51_RS07980	COG0540	Belongs to the ATCase OTCase family
GJV51_RS07990	COG3679	Belongs to the UPF0342 family
GJV51_RS07995	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GJV51_RS08000	COG1438	arginine binding
GJV51_RS08005	COG0018	arginyl-trna synthetase
GJV51_RS08015	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GJV51_RS08050	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GJV51_RS08060	COG1131	(ABC) transporter
GJV51_RS08065	COG0537	adenosine 5'-monophosphoramidase activity
GJV51_RS08075	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GJV51_RS08080	COG1028	Short-chain dehydrogenase reductase Sdr
GJV51_RS08090	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GJV51_RS08095	COG0358	DNA primase activity
GJV51_RS08110	COG3716	PTS system mannose fructose sorbose family IID component
GJV51_RS08140	COG0758	DNA mediated transformation
GJV51_RS08145	COG0488	(ABC) transporter
GJV51_RS08150	COG0167	dihydroorotate dehydrogenase activity
GJV51_RS08155	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GJV51_RS08170	COG2183	response to ionizing radiation
GJV51_RS08185	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GJV51_RS08190	COG0626	cystathionine gamma-synthase activity
GJV51_RS08195	COG1045	serine acetyltransferase
GJV51_RS08205	COG0776	regulation of translation
GJV51_RS08210	COG1160	GTP binding
GJV51_RS08215	COG0539	negative regulation of cytoplasmic translation
GJV51_RS08220	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GJV51_RS08230	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GJV51_RS08235	COG1187	pseudouridine synthase activity
GJV51_RS08240	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GJV51_RS08245	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GJV51_RS08255	COG4974	Belongs to the 'phage' integrase family
GJV51_RS08260	COG2996	Protein conserved in bacteria
GJV51_RS08265	COG1610	YqeY-like protein
GJV51_RS08270	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GJV51_RS08275	COG0477	Major facilitator Superfamily
GJV51_RS08280	COG2508	Transcriptional regulator
GJV51_RS08285	COG1113	amino acid transport
GJV51_RS08290	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GJV51_RS08295	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GJV51_RS08300	COG0124	histidyl-tRNA synthetase
GJV51_RS08310	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GJV51_RS08315	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GJV51_RS08325	COG4470	Protein conserved in bacteria
GJV51_RS08330	COG0737	Belongs to the 5'-nucleotidase family
GJV51_RS08340	COG0006	proline dipeptidase activity
GJV51_RS08345	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GJV51_RS08350	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GJV51_RS08380	COG1247	-acetyltransferase
GJV51_RS08385	COG2962	Rard protein
GJV51_RS08410	COG1217	gtp-binding protein TYPA
GJV51_RS08415	COG0483	inositol monophosphate 1-phosphatase activity
GJV51_RS08420	COG4476	Belongs to the UPF0223 family
GJV51_RS08425	COG0242	peptide deformylase activity
GJV51_RS08430	COG0484	heat shock protein binding
GJV51_RS08435	COG0443	Heat shock 70 kDa protein
GJV51_RS08440	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GJV51_RS08445	COG1420	regulation of RNA biosynthetic process
GJV51_RS08450	COG0196	riboflavin kinase activity
GJV51_RS08455	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GJV51_RS08465	COG0436	Aminotransferase
GJV51_RS08470	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GJV51_RS08475	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GJV51_RS08485	COG2740	Nucleic-acid-binding protein implicated in transcription termination
GJV51_RS08490	COG0195	Participates in both transcription termination and antitermination
GJV51_RS08495	COG0779	Required for maturation of 30S ribosomal subunits
GJV51_RS08500	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GJV51_RS08505	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GJV51_RS08510	COG1227	inorganic diphosphatase activity
GJV51_RS08520	COG0187	DNA topoisomerase II activity
GJV51_RS08530	COG1490	D-aminoacyl-tRNA deacylase activity
GJV51_RS08535	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GJV51_RS08540	COG2814	Major facilitator Superfamily
GJV51_RS08555	COG0505	Belongs to the CarA family
GJV51_RS08560	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GJV51_RS08565	COG0564	pseudouridine synthase activity
GJV51_RS08575	COG0328	RNA-DNA hybrid ribonuclease activity
GJV51_RS08585	COG0436	Aminotransferase
GJV51_RS08590	COG0116	Belongs to the methyltransferase superfamily
GJV51_RS08605	COG0017	Asparaginyl-tRNA synthetase
GJV51_RS08610	COG0436	Aminotransferase
GJV51_RS08620	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GJV51_RS08620	COG1199	ATP-dependent helicase activity
GJV51_RS08640	COG1304	FMN binding
GJV51_RS08650	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GJV51_RS08655	COG2116	formate transmembrane transporter activity
GJV51_RS08660	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GJV51_RS08665	COG0716	FMN binding
GJV51_RS08670	COG2246	polysaccharide biosynthetic process
GJV51_RS08675	COG1216	Glycosyl transferase, family 2
GJV51_RS08685	COG1368	sulfuric ester hydrolase activity
GJV51_RS08700	COG0463	Glycosyl transferase, family 2
GJV51_RS08705	COG0562	UDP-galactopyranose mutase
GJV51_RS08725	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GJV51_RS08785	COG0024	Methionine aminopeptidase
GJV51_RS08790	COG1316	TRANSCRIPTIONal
GJV51_RS08795	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GJV51_RS08800	COG1114	Component of the transport system for branched-chain amino acids
GJV51_RS08805	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GJV51_RS08810	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GJV51_RS08830	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GJV51_RS08835	COG3142	Participates in the control of copper homeostasis
GJV51_RS08865	COG2910	NAD(P)H-binding
GJV51_RS08870	COG1733	regulation of RNA biosynthetic process
GJV51_RS08885	COG1937	Protein conserved in bacteria
GJV51_RS08890	COG0446	pyridine nucleotide-disulphide oxidoreductase
GJV51_RS08895	COG3118	belongs to the thioredoxin family
GJV51_RS08900	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GJV51_RS08905	COG1522	sequence-specific DNA binding
GJV51_RS08975	COG0433	COG0433 Predicted ATPase
GJV51_RS09015	COG2946	Replication initiation factor
GJV51_RS09045	COG1396	sequence-specific DNA binding
GJV51_RS09055	COG1192	Involved in chromosome partitioning
GJV51_RS09085	COG3118	belongs to the thioredoxin family
GJV51_RS09090	COG1573	uracil-dna glycosylase
GJV51_RS09095	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GJV51_RS09100	COG2801	Transposase and inactivated derivatives
GJV51_RS09120	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GJV51_RS09185	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GJV51_RS09195	COG4619	ABC transporter
GJV51_RS09200	COG0390	transport system, permease component
GJV51_RS09230	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GJV51_RS09235	COG0783	Belongs to the Dps family
GJV51_RS09260	COG1937	Protein conserved in bacteria
GJV51_RS09265	COG0446	pyridine nucleotide-disulphide oxidoreductase
GJV51_RS09270	COG3118	belongs to the thioredoxin family
GJV51_RS09330	COG1192	Involved in chromosome partitioning