locus-tag	class	description
CCX79_RS00015	COG0436	Aminotransferase
CCX79_RS00020	COG0194	GDP metabolic process
CCX79_RS00025	COG0531	amino acid
CCX79_RS00030	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
CCX79_RS00035	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CCX79_RS00050	COG5506	Protein of unknown function (DUF1694)
CCX79_RS00055	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CCX79_RS00070	COG0833	amino acid
CCX79_RS00080	COG1316	TRANSCRIPTIONal
CCX79_RS00090	COG4166	transmembrane transport
CCX79_RS00095	COG1181	Belongs to the D-alanine--D-alanine ligase family
CCX79_RS00095	COG2918	glutathione biosynthetic process
CCX79_RS00100	COG0531	amino acid
CCX79_RS00110	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CCX79_RS00125	COG0628	permease
CCX79_RS00130	COG1194	a g-specific adenine glycosylase
CCX79_RS00135	COG2814	Major facilitator Superfamily
CCX79_RS00140	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CCX79_RS00150	COG1902	pentaerythritol trinitrate reductase activity
CCX79_RS00155	COG1388	LysM domain
CCX79_RS00155	COG1705	Flagellar rod assembly protein muramidase FlgJ
CCX79_RS00160	COG0737	Belongs to the 5'-nucleotidase family
CCX79_RS00165	COG3639	organic phosphonate transmembrane transporter activity
CCX79_RS00175	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CCX79_RS00185	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CCX79_RS00190	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CCX79_RS00195	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CCX79_RS00200	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CCX79_RS00205	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CCX79_RS00210	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CCX79_RS00215	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CCX79_RS00220	COG0356	it plays a direct role in the translocation of protons across the membrane
CCX79_RS00230	COG0588	phosphoglycerate mutase activity
CCX79_RS00235	COG1278	Cold shock
CCX79_RS00250	COG1072	(Pantothenic acid kinase))
CCX79_RS00255	COG3973	AAA domain
CCX79_RS00300	COG0318	PFAM AMP-dependent synthetase and ligase
CCX79_RS00305	COG0318	PFAM AMP-dependent synthetase and ligase
CCX79_RS00330	COG1511	domain protein
CCX79_RS00330	COG1511	domain protein
CCX79_RS00335	COG1309	transcriptional regulator
CCX79_RS00345	COG0697	spore germination
CCX79_RS00355	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CCX79_RS00365	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CCX79_RS00380	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CCX79_RS00435	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CCX79_RS00435	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CCX79_RS00440	COG0488	(ABC) transporter
CCX79_RS00460	COG1064	alcohol dehydrogenase
CCX79_RS00470	COG0126	phosphoglycerate kinase activity
CCX79_RS00500	COG3590	peptidase
CCX79_RS00505	COG4608	Belongs to the ABC transporter superfamily
CCX79_RS00510	COG0444	Belongs to the ABC transporter superfamily
CCX79_RS00515	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CCX79_RS00520	COG0601	transmembrane transport
CCX79_RS00525	COG4166	transmembrane transport
CCX79_RS00530	COG0765	amino acid transport
CCX79_RS00535	COG0765	amino acid transport
CCX79_RS00540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CCX79_RS00545	COG1126	abc transporter atp-binding protein
CCX79_RS00550	COG1132	(ABC) transporter
CCX79_RS00555	COG1132	(ABC) transporter
CCX79_RS00565	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CCX79_RS00570	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CCX79_RS00575	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CCX79_RS00580	COG1959	2 iron, 2 sulfur cluster binding
CCX79_RS00585	COG1511	domain protein
CCX79_RS00590	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CCX79_RS00595	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CCX79_RS00615	COG0745	RESPONSE REGULATOR receiver
CCX79_RS00620	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CCX79_RS00635	COG0473	3-isopropylmalate dehydrogenase activity
CCX79_RS00645	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CCX79_RS00650	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CCX79_RS00660	COG0028	Belongs to the TPP enzyme family
CCX79_RS00670	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
CCX79_RS00675	COG2188	Transcriptional regulator
CCX79_RS00680	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CCX79_RS00690	COG0737	Belongs to the 5'-nucleotidase family
CCX79_RS00695	COG0305	Participates in initiation and elongation during chromosome replication
CCX79_RS00700	COG0359	binds to the 23S rRNA
CCX79_RS00710	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CCX79_RS00715	COG0629	single-stranded DNA binding
CCX79_RS00720	COG0360	Binds together with S18 to 16S ribosomal RNA
CCX79_RS00735	COG1122	ATPase activity
CCX79_RS00740	COG4720	Psort location CytoplasmicMembrane, score
CCX79_RS00750	COG0514	ATP-dependent DNA helicase (RecQ)
CCX79_RS00810	COG3866	Pectate lyase
CCX79_RS00815	COG2084	Dehydrogenase
CCX79_RS00845	COG3623	hexulose-6-phosphate isomerase
CCX79_RS00880	COG0561	phosphatase activity
CCX79_RS00895	COG3402	PFAM membrane-flanked domain
CCX79_RS00900	COG0583	DNA-binding transcription factor activity
CCX79_RS00905	COG1113	amino acid transport
CCX79_RS00910	COG1757	Na H antiporter
CCX79_RS00925	COG1733	regulation of RNA biosynthetic process
CCX79_RS00930	COG0667	Aldo Keto reductase
CCX79_RS00940	COG0667	Aldo Keto reductase
CCX79_RS00950	COG2814	Major facilitator Superfamily
CCX79_RS00960	COG1686	Belongs to the peptidase S11 family
CCX79_RS00970	COG0803	Belongs to the bacterial solute-binding protein 9 family
CCX79_RS00975	COG2226	methyltransferase
CCX79_RS00980	COG0318	PFAM AMP-dependent synthetase and ligase
CCX79_RS00990	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
CCX79_RS01020	COG0066	3-isopropylmalate dehydratase activity
CCX79_RS01025	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CCX79_RS01030	COG0473	3-isopropylmalate dehydrogenase activity
CCX79_RS01035	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CCX79_RS01040	COG2151	metal-sulfur cluster biosynthetic enzyme
CCX79_RS01045	COG0719	Fe-S assembly protein
CCX79_RS01060	COG0719	Fe-S assembly protein
CCX79_RS01065	COG0396	ATPase activity
CCX79_RS01075	COG0129	dihydroxy-acid dehydratase activity
CCX79_RS01080	COG2151	metal-sulfur cluster biosynthetic enzyme
CCX79_RS01095	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CCX79_RS01110	COG1983	PspC domain protein
CCX79_RS01120	COG2918	glutathione biosynthetic process
CCX79_RS01120	COG1181	Belongs to the D-alanine--D-alanine ligase family
CCX79_RS01125	COG0577	efflux transmembrane transporter activity
CCX79_RS01130	COG1136	(ABC) transporter
CCX79_RS01160	COG2855	membrane
CCX79_RS01180	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CCX79_RS01200	COG0706	membrane insertase activity
CCX79_RS01205	COG0594	ribonuclease P activity
CCX79_RS01210	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CCX79_RS01215	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CCX79_RS01220	COG0446	pyridine nucleotide-disulphide oxidoreductase
CCX79_RS01230	COG2084	Dehydrogenase
CCX79_RS01235	COG0561	phosphatase activity
CCX79_RS01260	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CCX79_RS01265	COG0592	DNA-directed DNA polymerase activity
CCX79_RS01275	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CCX79_RS01280	COG0187	DNA topoisomerase II activity
CCX79_RS01290	COG0386	Belongs to the glutathione peroxidase family
CCX79_RS01320	COG1073	alpha beta
CCX79_RS01335	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CCX79_RS01340	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CCX79_RS01345	COG0436	Aminotransferase
CCX79_RS01445	COG2814	Major facilitator Superfamily
CCX79_RS01450	COG0647	UMP catabolic process
CCX79_RS01470	COG1368	sulfuric ester hydrolase activity
CCX79_RS01475	COG0438	transferase activity, transferring glycosyl groups
CCX79_RS01485	COG0564	pseudouridine synthase activity
CCX79_RS01490	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CCX79_RS01495	COG2217	Heavy metal translocating P-type atpase
CCX79_RS01505	COG1725	Transcriptional regulator
CCX79_RS01510	COG1131	(ABC) transporter
CCX79_RS01520	COG1131	(ABC) transporter
CCX79_RS01530	COG0656	L-ascorbic acid biosynthetic process
CCX79_RS01540	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CCX79_RS01545	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CCX79_RS01550	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CCX79_RS01555	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CCX79_RS01560	COG1881	PFAM PEBP family protein
CCX79_RS01575	COG0569	domain protein
CCX79_RS01585	COG2271	Major facilitator Superfamily
CCX79_RS01615	COG3845	ABC transporter
CCX79_RS01620	COG4603	Belongs to the binding-protein-dependent transport system permease family
CCX79_RS01625	COG1079	Belongs to the binding-protein-dependent transport system permease family
CCX79_RS01640	COG4120	Belongs to the binding-protein-dependent transport system permease family
CCX79_RS01650	COG1396	sequence-specific DNA binding
CCX79_RS01655	COG1028	Short-chain dehydrogenase reductase Sdr
CCX79_RS01735	COG1053	succinate dehydrogenase
CCX79_RS01740	COG1131	(ABC) transporter
CCX79_RS01750	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CCX79_RS01755	COG0463	Glycosyl transferase, family 2
CCX79_RS01765	COG0446	pyridine nucleotide-disulphide oxidoreductase
CCX79_RS01780	COG1464	Belongs to the NlpA lipoprotein family
CCX79_RS01790	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CCX79_RS01795	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CCX79_RS01800	COG1307	EDD domain protein, DegV family
CCX79_RS01805	COG1272	protein, Hemolysin III
CCX79_RS01825	COG2115	Belongs to the xylose isomerase family
CCX79_RS01840	COG1968	undecaprenyl-diphosphatase activity
CCX79_RS01855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CCX79_RS01860	COG0765	amino acid transport
CCX79_RS01865	COG0765	amino acid transport
CCX79_RS01870	COG1126	abc transporter atp-binding protein
CCX79_RS01875	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CCX79_RS01885	COG4720	Psort location CytoplasmicMembrane, score
CCX79_RS01890	COG0351	phosphomethylpyrimidine kinase
CCX79_RS01905	COG1012	belongs to the aldehyde dehydrogenase family
CCX79_RS01905	COG1454	alcohol dehydrogenase
CCX79_RS01910	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CCX79_RS01945	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CCX79_RS01955	COG0756	dUTP diphosphatase activity
CCX79_RS01975	COG1309	transcriptional regulator
CCX79_RS01980	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CCX79_RS01985	COG0215	cysteine-tRNA ligase activity
CCX79_RS02085	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CCX79_RS02090	COG0653	protein targeting
CCX79_RS02095	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CCX79_RS02100	COG0542	response to heat
CCX79_RS02105	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CCX79_RS02110	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CCX79_RS02115	COG0049	tRNA binding
CCX79_RS02120	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CCX79_RS02125	COG2807	transmembrane transport
CCX79_RS02130	COG3842	ATPase activity
CCX79_RS02135	COG1177	transmembrane transport
CCX79_RS02140	COG1177	transmembrane transport
CCX79_RS02145	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CCX79_RS02150	COG0051	transcription antitermination factor activity, RNA binding
CCX79_RS02155	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CCX79_RS02160	COG0088	Forms part of the polypeptide exit tunnel
CCX79_RS02165	COG0089	rRNA binding
CCX79_RS02170	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CCX79_RS02175	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CCX79_RS02180	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CCX79_RS02185	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CCX79_RS02190	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CCX79_RS02195	COG0255	Belongs to the universal ribosomal protein uL29 family
CCX79_RS02200	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CCX79_RS02205	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CCX79_RS02210	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CCX79_RS02215	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CCX79_RS02220	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CCX79_RS02225	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CCX79_RS02230	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CCX79_RS02235	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CCX79_RS02240	COG1841	ribosomal large subunit assembly
CCX79_RS02245	COG0200	Binds to the 23S rRNA
CCX79_RS02255	COG0563	adenylate kinase activity
CCX79_RS02260	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CCX79_RS02265	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CCX79_RS02270	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CCX79_RS02275	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CCX79_RS02280	COG0202	RNA polymerase activity
CCX79_RS02285	COG0203	ribosomal protein L17
CCX79_RS02290	COG0142	geranyltranstransferase activity
CCX79_RS02300	COG1122	ATPase activity
CCX79_RS02305	COG1122	ATPase activity
CCX79_RS02310	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CCX79_RS02315	COG0101	tRNA pseudouridine synthase activity
CCX79_RS02325	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CCX79_RS02330	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CCX79_RS02335	COG0583	DNA-binding transcription factor activity
CCX79_RS02340	COG1902	pentaerythritol trinitrate reductase activity
CCX79_RS02375	COG0149	triose-phosphate isomerase activity
CCX79_RS02380	COG0148	phosphopyruvate hydratase activity
CCX79_RS02385	COG0519	Catalyzes the synthesis of GMP from XMP
CCX79_RS02395	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CCX79_RS02400	COG0248	Ppx GppA phosphatase
CCX79_RS02405	COG1739	Uncharacterized protein family UPF0029
CCX79_RS02410	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CCX79_RS02415	COG1040	competence protein
CCX79_RS02430	COG0588	phosphoglycerate mutase activity
CCX79_RS02435	COG1253	flavin adenine dinucleotide binding
CCX79_RS02440	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CCX79_RS02445	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CCX79_RS02450	COG1780	Probably involved in ribonucleotide reductase function
CCX79_RS02465	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CCX79_RS02480	COG1077	Cell shape determining protein MreB Mrl
CCX79_RS02490	COG0772	Belongs to the SEDS family
CCX79_RS02500	COG1181	Belongs to the D-alanine--D-alanine ligase family
CCX79_RS02510	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CCX79_RS02515	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CCX79_RS02525	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CCX79_RS02530	COG0081	regulation of translation
CCX79_RS02535	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CCX79_RS02540	COG0222	ribosome binding
CCX79_RS02545	COG2813	Specifically methylates the guanine in position
CCX79_RS02550	COG0590	tRNA wobble adenosine to inosine editing
CCX79_RS02565	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CCX79_RS02570	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CCX79_RS02580	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CCX79_RS02585	COG3870	Protein conserved in bacteria
CCX79_RS02590	COG0470	DNA polymerase III
CCX79_RS02605	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CCX79_RS02630	COG1609	Transcriptional regulator
CCX79_RS02640	COG1621	beta-fructofuranosidase activity
CCX79_RS02645	COG1940	carbohydrate kinase activity
CCX79_RS02660	COG1428	Deoxynucleoside kinase
CCX79_RS02665	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CCX79_RS02670	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CCX79_RS02680	COG0492	ferredoxin-NADP+ reductase activity
CCX79_RS02690	COG1418	mRNA catabolic process
CCX79_RS02695	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CCX79_RS02695	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CCX79_RS02700	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CCX79_RS02700	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CCX79_RS02730	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CCX79_RS02740	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CCX79_RS02745	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CCX79_RS02755	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CCX79_RS02760	COG1028	Short-chain dehydrogenase reductase Sdr
CCX79_RS02765	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CCX79_RS02770	COG0511	ligase activity, forming carbon-carbon bonds
CCX79_RS02780	COG0439	Biotin carboxylase
CCX79_RS02785	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CCX79_RS02830	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
CCX79_RS02855	COG0525	valine-tRNA ligase activity
CCX79_RS02860	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CCX79_RS02875	COG1388	LysM domain
CCX79_RS02875	COG3103	Sh3 type 3 domain protein
CCX79_RS02875	COG0791	NLP P60 protein
CCX79_RS02885	COG0768	penicillin binding
CCX79_RS02890	COG0640	Transcriptional regulator
CCX79_RS02900	COG1136	(ABC) transporter
CCX79_RS02900	COG0577	efflux transmembrane transporter activity
CCX79_RS02905	COG1316	TRANSCRIPTIONal
CCX79_RS02930	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CCX79_RS02940	COG1914	H( )-stimulated, divalent metal cation uptake system
CCX79_RS02950	COG0640	Transcriptional regulator
CCX79_RS02965	COG1957	nucleoside hydrolase
CCX79_RS02975	COG1192	Involved in chromosome partitioning
CCX79_RS02980	COG1475	DNA binding
CCX79_RS02985	COG4481	Protein conserved in bacteria
CCX79_RS02990	COG0012	GTP binding
CCX79_RS03000	COG0745	RESPONSE REGULATOR receiver
CCX79_RS03005	COG2205	protein histidine kinase activity
CCX79_RS03015	COG0363	glucosamine-6-phosphate deaminase activity
CCX79_RS03020	COG0166	Belongs to the GPI family
CCX79_RS03030	COG4175	Glycine betaine
CCX79_RS03030	COG3448	diguanylate cyclase activity
CCX79_RS03050	COG4152	abc transporter atp-binding protein
CCX79_RS03085	COG0765	amino acid transport
CCX79_RS03090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CCX79_RS03100	COG1126	abc transporter atp-binding protein
CCX79_RS03105	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CCX79_RS03110	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CCX79_RS03115	COG1126	abc transporter atp-binding protein
CCX79_RS03120	COG2814	Major facilitator Superfamily
CCX79_RS03125	COG0343	queuine tRNA-ribosyltransferase activity
CCX79_RS03130	COG1862	Preprotein translocase
CCX79_RS03140	COG0392	lysyltransferase activity
CCX79_RS03140	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CCX79_RS03155	COG0406	alpha-ribazole phosphatase activity
CCX79_RS03170	COG1132	(ABC) transporter
CCX79_RS03175	COG1132	(ABC) transporter
CCX79_RS03180	COG0438	transferase activity, transferring glycosyl groups
CCX79_RS03200	COG1368	sulfuric ester hydrolase activity
CCX79_RS03205	COG0556	nucleotide-excision repair
CCX79_RS03210	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CCX79_RS03215	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CCX79_RS03220	COG1481	regulation of sporulation
CCX79_RS03225	COG0740	serine-type endopeptidase activity
CCX79_RS03235	COG0193	aminoacyl-tRNA hydrolase activity
CCX79_RS03240	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CCX79_RS03245	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CCX79_RS03255	COG0037	tRNA processing
CCX79_RS03265	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CCX79_RS03270	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CCX79_RS03275	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CCX79_RS03300	COG0217	transcriptional regulatory protein
CCX79_RS03305	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CCX79_RS03315	COG2252	PERMEase
CCX79_RS03320	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CCX79_RS03360	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CCX79_RS03370	COG2188	Transcriptional regulator
CCX79_RS03380	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CCX79_RS03390	COG1464	Belongs to the NlpA lipoprotein family
CCX79_RS03425	COG1744	ABC transporter substrate-binding protein PnrA-like
CCX79_RS03430	COG0765	amino acid transport
CCX79_RS03435	COG1126	abc transporter atp-binding protein
CCX79_RS03440	COG0765	amino acid transport
CCX79_RS03470	COG1733	regulation of RNA biosynthetic process
CCX79_RS03475	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CCX79_RS03480	COG0072	phenylalanine-tRNA ligase activity
CCX79_RS03480	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CCX79_RS03485	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CCX79_RS03490	COG0254	rRNA binding
CCX79_RS03495	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CCX79_RS03500	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CCX79_RS03505	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CCX79_RS03520	COG2814	Major facilitator Superfamily
CCX79_RS03525	COG2003	Belongs to the UPF0758 family
CCX79_RS03530	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CCX79_RS03535	COG2131	deaminase
CCX79_RS03540	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CCX79_RS03545	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CCX79_RS03555	COG4537	Required for transformation and DNA binding
CCX79_RS03585	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CCX79_RS03595	COG4975	Glucose uptake
CCX79_RS03600	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CCX79_RS03635	COG0683	leucine binding
CCX79_RS03650	COG0411	ABC transporter
CCX79_RS03660	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CCX79_RS03665	COG0351	phosphomethylpyrimidine kinase
CCX79_RS03670	COG0352	thiamine-phosphate diphosphorylase activity
CCX79_RS03675	COG1012	belongs to the aldehyde dehydrogenase family
CCX79_RS03715	COG4493	Belongs to the UPF0637 family
CCX79_RS03725	COG1609	Transcriptional regulator
CCX79_RS03745	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CCX79_RS03755	COG0308	aminopeptidase N
CCX79_RS03765	COG2936	dipeptidyl-peptidase activity
CCX79_RS03775	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CCX79_RS03775	COG2190	(PTS) system
CCX79_RS03775	COG1263	PTS System
CCX79_RS03780	COG0366	Alpha amylase catalytic
CCX79_RS03785	COG2188	Transcriptional regulator
CCX79_RS03790	COG1078	dGTPase activity
CCX79_RS03800	COG3343	RNA polymerase activity
CCX79_RS03810	COG1113	amino acid transport
CCX79_RS03815	COG1268	BioY protein
CCX79_RS03825	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CCX79_RS03825	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CCX79_RS03830	COG0504	CTP synthase activity
CCX79_RS03835	COG0322	excinuclease ABC activity
CCX79_RS03840	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CCX79_RS03845	COG0028	Belongs to the TPP enzyme family
CCX79_RS03855	COG2309	aminopeptidase activity
CCX79_RS03865	COG0673	inositol 2-dehydrogenase activity
CCX79_RS03870	COG0513	Belongs to the DEAD box helicase family
CCX79_RS03875	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CCX79_RS03885	COG0237	dephospho-CoA kinase activity
CCX79_RS03895	COG1484	DNA-dependent DNA replication
CCX79_RS03920	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CCX79_RS03925	COG0416	fatty acid biosynthetic process
CCX79_RS03930	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CCX79_RS03935	COG3091	SprT-like family
CCX79_RS03940	COG0561	phosphatase activity
CCX79_RS03955	COG0006	proline dipeptidase activity
CCX79_RS03960	COG1609	Transcriptional regulator
CCX79_RS03965	COG2755	lipolytic protein G-D-S-L family
CCX79_RS03965	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CCX79_RS03970	COG2814	Major facilitator Superfamily
CCX79_RS03985	COG3527	Alpha-acetolactate decarboxylase
CCX79_RS03990	COG1737	Transcriptional regulator
CCX79_RS03995	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CCX79_RS04010	COG0531	amino acid
CCX79_RS04020	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CCX79_RS04025	COG4472	Bacterial protein of unknown function (DUF965)
CCX79_RS04030	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CCX79_RS04035	COG3906	Belongs to the UPF0473 family
CCX79_RS04040	COG1271	oxidase subunit
CCX79_RS04045	COG1294	oxidase, subunit
CCX79_RS04050	COG4988	ABC transporter
CCX79_RS04055	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CCX79_RS04060	COG1705	Flagellar rod assembly protein muramidase FlgJ
CCX79_RS04065	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CCX79_RS04080	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CCX79_RS04095	COG0542	response to heat
CCX79_RS04100	COG1077	Cell shape determining protein MreB Mrl
CCX79_RS04115	COG0765	amino acid transport
CCX79_RS04125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CCX79_RS04135	COG0612	Peptidase, M16
CCX79_RS04140	COG0612	Peptidase, M16
CCX79_RS04145	COG1426	Protein conserved in bacteria
CCX79_RS04150	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CCX79_RS04155	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CCX79_RS04160	COG0745	RESPONSE REGULATOR receiver
CCX79_RS04170	COG5002	protein histidine kinase activity
CCX79_RS04180	COG0573	inorganic phosphate transmembrane transporter activity
CCX79_RS04185	COG0581	inorganic phosphate transmembrane transporter activity
CCX79_RS04190	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CCX79_RS04195	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CCX79_RS04200	COG0704	Plays a role in the regulation of phosphate uptake
CCX79_RS04205	COG1950	PFAM Membrane protein of
CCX79_RS04210	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CCX79_RS04215	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CCX79_RS04220	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CCX79_RS04225	COG0492	ferredoxin-NADP+ reductase activity
CCX79_RS04240	COG1063	alcohol dehydrogenase
CCX79_RS04245	COG1609	Transcriptional regulator
CCX79_RS04255	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CCX79_RS04260	COG0335	large ribosomal subunit rRNA binding
CCX79_RS04265	COG1719	4-vinyl reductase, 4VR
CCX79_RS04270	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CCX79_RS04275	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CCX79_RS04285	COG2255	four-way junction helicase activity
CCX79_RS04295	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CCX79_RS04300	COG0584	glycerophosphoryl diester phosphodiesterase
CCX79_RS04305	COG0632	four-way junction helicase activity
CCX79_RS04310	COG1428	Deoxynucleoside kinase
CCX79_RS04315	COG1970	mechanosensitive ion channel activity
CCX79_RS04320	COG0577	efflux transmembrane transporter activity
CCX79_RS04325	COG1136	(ABC) transporter
CCX79_RS04330	COG4684	Psort location CytoplasmicMembrane, score
CCX79_RS04340	COG4684	Psort location CytoplasmicMembrane, score
CCX79_RS04360	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CCX79_RS04365	COG1126	abc transporter atp-binding protein
CCX79_RS04370	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CCX79_RS04380	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CCX79_RS04390	COG0671	phosphoesterase, PA-phosphatase related
CCX79_RS04395	COG0495	leucyl-tRNA aminoacylation
CCX79_RS04400	COG2244	polysaccharide biosynthetic process
CCX79_RS04415	COG1704	LemA family
CCX79_RS04420	COG0501	Belongs to the peptidase M48B family
CCX79_RS04425	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CCX79_RS04430	COG1942	4-Oxalocrotonate Tautomerase
CCX79_RS04440	COG3237	CsbD-like
CCX79_RS04445	COG0516	GMP reductase activity
CCX79_RS04445	COG0517	IMP dehydrogenase activity
CCX79_RS04450	COG0517	IMP dehydrogenase activity
CCX79_RS04450	COG0516	GMP reductase activity
CCX79_RS04465	COG3331	DNA recombination
CCX79_RS04475	COG4474	Belongs to the UPF0398 family
CCX79_RS04480	COG3599	regulation of cell shape
CCX79_RS04490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CCX79_RS04495	COG2706	6-phosphogluconolactonase activity
CCX79_RS04500	COG0628	permease
CCX79_RS04515	COG1280	lysine exporter protein (LysE YggA)
CCX79_RS04515	COG1674	ftsk spoiiie
CCX79_RS04520	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CCX79_RS04525	COG1113	amino acid transport
CCX79_RS04530	COG0586	Pfam SNARE associated Golgi protein
CCX79_RS04540	COG3001	Fructosamine kinase
CCX79_RS04550	COG2171	N-acyltransferase activity
CCX79_RS04555	COG1473	amidohydrolase
CCX79_RS04560	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CCX79_RS04565	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CCX79_RS04570	COG2137	regulation of response to DNA damage stimulus
CCX79_RS04575	COG3557	Belongs to the UPF0374 family
CCX79_RS04580	COG0705	Rhomboid family
CCX79_RS04590	COG1940	carbohydrate kinase activity
CCX79_RS04600	COG2357	RelA SpoT domain protein
CCX79_RS04605	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CCX79_RS04610	COG0564	pseudouridine synthase activity
CCX79_RS04615	COG2239	Acts as a magnesium transporter
CCX79_RS04625	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CCX79_RS04630	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CCX79_RS04635	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CCX79_RS04640	COG4589	Belongs to the CDS family
CCX79_RS04645	COG0750	zinc metalloprotease
CCX79_RS04650	COG0442	prolyl-tRNA aminoacylation
CCX79_RS04655	COG2176	DNA-directed DNA polymerase activity
CCX79_RS04670	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
CCX79_RS04670	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CCX79_RS04690	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CCX79_RS04695	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CCX79_RS04705	COG0667	Aldo Keto reductase
CCX79_RS04710	COG0151	Belongs to the GarS family
CCX79_RS04715	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CCX79_RS04720	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CCX79_RS04725	COG1278	Cold shock
CCX79_RS04730	COG0494	nUDIX hydrolase
CCX79_RS04740	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CCX79_RS04745	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CCX79_RS04750	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CCX79_RS04765	COG1621	beta-fructofuranosidase activity
CCX79_RS04770	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CCX79_RS04770	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CCX79_RS04775	COG3764	Sortase (surface protein transpeptidase)
CCX79_RS04785	COG0789	Transcriptional regulator
CCX79_RS04790	COG0174	glutamine synthetase
CCX79_RS04795	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CCX79_RS04800	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CCX79_RS04805	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CCX79_RS04810	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CCX79_RS04820	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CCX79_RS04830	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CCX79_RS04835	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CCX79_RS04840	COG0138	bifunctional purine biosynthesis protein purh
CCX79_RS04845	COG0420	3'-5' exonuclease activity
CCX79_RS04850	COG4717	serine-type aminopeptidase activity
CCX79_RS04870	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CCX79_RS04880	COG0095	Lipoate-protein ligase
CCX79_RS04895	COG0508	dehydrogenase complex catalyzes the overall conversion of
CCX79_RS04905	COG2267	carboxylic ester hydrolase activity
CCX79_RS04910	COG0584	glycerophosphoryl diester phosphodiesterase
CCX79_RS04930	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CCX79_RS04935	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CCX79_RS04945	COG0351	phosphomethylpyrimidine kinase
CCX79_RS04950	COG1169	isochorismate synthase
CCX79_RS04955	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CCX79_RS04975	COG0617	tRNA 3'-terminal CCA addition
CCX79_RS04985	COG1307	EDD domain protein, DegV family
CCX79_RS05005	COG2755	lipolytic protein G-D-S-L family
CCX79_RS05015	COG4479	Belongs to the UPF0346 family
CCX79_RS05020	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CCX79_RS05025	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CCX79_RS05035	COG1122	ATPase activity
CCX79_RS05050	COG2384	SAM-dependent methyltransferase
CCX79_RS05055	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CCX79_RS05070	COG0587	DNA-directed DNA polymerase activity
CCX79_RS05080	COG0004	ammonium transporteR
CCX79_RS05085	COG1702	phosphate starvation-inducible protein PhoH
CCX79_RS05090	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CCX79_RS05100	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CCX79_RS05105	COG1381	Involved in DNA repair and RecF pathway recombination
CCX79_RS05110	COG0252	asparaginase activity
CCX79_RS05120	COG0527	aspartate kinase activity
CCX79_RS05125	COG0083	homoserine kinase activity
CCX79_RS05130	COG0460	homoserine dehydrogenase
CCX79_RS05135	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CCX79_RS05140	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CCX79_RS05145	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CCX79_RS05155	COG0183	Belongs to the thiolase family
CCX79_RS05160	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CCX79_RS05185	COG1609	Transcriptional regulator
CCX79_RS05190	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CCX79_RS05210	COG0517	IMP dehydrogenase activity
CCX79_RS05210	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CCX79_RS05215	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CCX79_RS05230	COG1121	(ABC) transporter
CCX79_RS05235	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CCX79_RS05260	COG0415	Belongs to the DNA photolyase family
CCX79_RS05265	COG0577	efflux transmembrane transporter activity
CCX79_RS05275	COG1309	transcriptional regulator
CCX79_RS05280	COG1033	growth of symbiont in host cell
CCX79_RS05280	COG2409	Drug exporters of the RND superfamily
CCX79_RS05295	COG0069	glutamate synthase activity
CCX79_RS05295	COG0070	glutamate synthase
CCX79_RS05295	COG0067	glutamate synthase
CCX79_RS05300	COG0493	'glutamate synthase
CCX79_RS05320	COG0307	riboflavin synthase, alpha
CCX79_RS05330	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CCX79_RS05335	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CCX79_RS05345	COG0738	Major facilitator superfamily
CCX79_RS05350	COG0366	Alpha amylase catalytic
CCX79_RS05355	COG1609	Transcriptional regulator
CCX79_RS05360	COG0693	protein deglycase activity
CCX79_RS05365	COG0745	RESPONSE REGULATOR receiver
CCX79_RS05370	COG5002	protein histidine kinase activity
CCX79_RS05375	COG1136	(ABC) transporter
CCX79_RS05385	COG0667	Aldo Keto reductase
CCX79_RS05395	COG2207	Transcriptional regulator
CCX79_RS05400	COG1874	Beta-galactosidase
CCX79_RS05430	COG0789	Transcriptional regulator
CCX79_RS05445	COG1609	Transcriptional regulator
CCX79_RS05450	COG2160	L-arabinose isomerase activity
CCX79_RS05475	COG5263	repeat protein
CCX79_RS05475	COG0366	Alpha amylase catalytic
CCX79_RS05480	COG1028	Short-chain dehydrogenase reductase Sdr
CCX79_RS05490	COG2261	transglycosylase associated protein
CCX79_RS05515	COG2261	transglycosylase associated protein
CCX79_RS05525	COG2814	Major facilitator Superfamily
CCX79_RS05530	COG5039	Polysaccharide pyruvyl transferase
CCX79_RS05565	COG1472	Belongs to the glycosyl hydrolase 3 family
CCX79_RS05590	COG1609	Transcriptional regulator
CCX79_RS05600	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CCX79_RS05605	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
CCX79_RS05615	COG1609	Transcriptional regulator
CCX79_RS05615	COG2207	Transcriptional regulator
CCX79_RS05650	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CCX79_RS05660	COG0366	Alpha amylase catalytic
CCX79_RS05675	COG3711	transcriptional antiterminator
CCX79_RS05685	COG2723	6-phospho-beta-galactosidase activity
CCX79_RS05690	COG1956	GAF domain-containing protein
CCX79_RS05695	COG2244	polysaccharide biosynthetic process
CCX79_RS05700	COG1609	Transcriptional regulator
CCX79_RS05715	COG0366	Alpha amylase catalytic
CCX79_RS05730	COG1215	transferase activity, transferring glycosyl groups
CCX79_RS05745	COG0300	oxidoreductase activity
CCX79_RS05755	COG0477	Major facilitator Superfamily
CCX79_RS05760	COG1063	alcohol dehydrogenase
CCX79_RS05765	COG1573	uracil-dna glycosylase
CCX79_RS05770	COG4720	Psort location CytoplasmicMembrane, score
CCX79_RS05775	COG0693	protein deglycase activity
CCX79_RS05800	COG1028	Short-chain dehydrogenase reductase Sdr
CCX79_RS05805	COG2610	gluconate transmembrane transporter activity
CCX79_RS05810	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CCX79_RS05820	COG2723	6-phospho-beta-galactosidase activity
CCX79_RS05830	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CCX79_RS05830	COG3711	transcriptional antiterminator
CCX79_RS05835	COG1447	Phosphotransferase system cellobiose-specific component IIA
CCX79_RS05845	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CCX79_RS05855	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CCX79_RS05865	COG1733	regulation of RNA biosynthetic process
CCX79_RS05870	COG1846	Transcriptional regulator
CCX79_RS05890	COG1442	glycosyl transferase family 8
CCX79_RS05895	COG1121	(ABC) transporter
CCX79_RS05900	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CCX79_RS05910	COG3527	Alpha-acetolactate decarboxylase
CCX79_RS05920	COG1316	TRANSCRIPTIONal
CCX79_RS05925	COG1846	Transcriptional regulator
CCX79_RS05930	COG2814	Major facilitator Superfamily
CCX79_RS05935	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CCX79_RS05955	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CCX79_RS05960	COG0300	oxidoreductase activity
CCX79_RS05970	COG2364	Membrane
CCX79_RS05975	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CCX79_RS05990	COG0028	Belongs to the TPP enzyme family
CCX79_RS05995	COG0071	Belongs to the small heat shock protein (HSP20) family
CCX79_RS06035	COG0745	RESPONSE REGULATOR receiver
CCX79_RS06040	COG5002	protein histidine kinase activity
CCX79_RS06040	COG3850	Histidine kinase
CCX79_RS06055	COG0655	NAD(P)H dehydrogenase (quinone) activity
CCX79_RS06095	COG1129	ABC transporter
CCX79_RS06115	COG2270	Major facilitator Superfamily
CCX79_RS06135	COG0583	DNA-binding transcription factor activity
CCX79_RS06150	COG2176	DNA-directed DNA polymerase activity
CCX79_RS06245	COG4336	lyase activity
CCX79_RS06250	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CCX79_RS06255	COG1914	H( )-stimulated, divalent metal cation uptake system
CCX79_RS06260	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CCX79_RS06265	COG1984	allophanate hydrolase subunit 2
CCX79_RS06300	COG0577	efflux transmembrane transporter activity
CCX79_RS06305	COG1136	(ABC) transporter
CCX79_RS06305	COG0577	efflux transmembrane transporter activity
CCX79_RS06345	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CCX79_RS06365	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CCX79_RS06380	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CCX79_RS06480	COG0542	response to heat
CCX79_RS06515	COG1192	Involved in chromosome partitioning
CCX79_RS06595	COG2826	transposase and inactivated derivatives, IS30 family
CCX79_RS06635	COG3158	transport of potassium into the cell
CCX79_RS06695	COG0433	COG0433 Predicted ATPase
CCX79_RS06720	COG1674	ftsk spoiiie
CCX79_RS06800	COG2169	Transcriptional regulator
CCX79_RS06800	COG1917	Cupin 2, conserved barrel domain protein
CCX79_RS06805	COG2197	response regulator
CCX79_RS06810	COG4585	Histidine kinase
CCX79_RS06815	COG2409	Drug exporters of the RND superfamily
CCX79_RS06830	COG2814	Major facilitator Superfamily
CCX79_RS06840	COG1028	Short-chain dehydrogenase reductase Sdr
CCX79_RS06850	COG0318	PFAM AMP-dependent synthetase and ligase
CCX79_RS06860	COG1116	anion transmembrane transporter activity
CCX79_RS06865	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CCX79_RS06880	COG0395	ABC-type sugar transport system, permease component
CCX79_RS06890	COG3842	ATPase activity
CCX79_RS06895	COG0710	3-dehydroquinate dehydratase activity
CCX79_RS06905	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CCX79_RS06910	COG0287	Prephenate dehydrogenase
CCX79_RS06915	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CCX79_RS06920	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CCX79_RS06925	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CCX79_RS06930	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CCX79_RS06945	COG0512	Glutamine amidotransferase of anthranilate synthase
CCX79_RS06950	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CCX79_RS06955	COG0159	tryptophan synthase activity
CCX79_RS06965	COG0134	indole-3-glycerol-phosphate synthase activity
CCX79_RS06970	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CCX79_RS06995	COG2848	UPF0210 protein
CCX79_RS07015	COG3425	synthase
CCX79_RS07020	COG0488	(ABC) transporter
CCX79_RS07030	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CCX79_RS07035	COG2264	protein methyltransferase activity
CCX79_RS07055	COG0673	inositol 2-dehydrogenase activity
CCX79_RS07060	COG0751	glycine-tRNA ligase activity
CCX79_RS07065	COG0752	glycyl-tRNA synthetase alpha subunit
CCX79_RS07075	COG0233	cytoplasmic translational termination
CCX79_RS07080	COG0528	UMP kinase activity
CCX79_RS07085	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CCX79_RS07090	COG0052	Belongs to the universal ribosomal protein uS2 family
CCX79_RS07095	COG2827	Endonuclease containing a URI domain
CCX79_RS07100	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CCX79_RS07105	COG0204	Acyl-transferase
CCX79_RS07110	COG3763	UPF0154 protein
CCX79_RS07115	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CCX79_RS07125	COG0284	orotidine-5'-phosphate decarboxylase activity
CCX79_RS07130	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CCX79_RS07135	COG0505	Belongs to the CarA family
CCX79_RS07140	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CCX79_RS07145	COG0540	Belongs to the ATCase OTCase family
CCX79_RS07155	COG3679	Belongs to the UPF0342 family
CCX79_RS07160	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CCX79_RS07165	COG1438	arginine binding
CCX79_RS07170	COG0018	arginyl-trna synthetase
CCX79_RS07180	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CCX79_RS07235	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CCX79_RS07245	COG1131	(ABC) transporter
CCX79_RS07250	COG0537	adenosine 5'-monophosphoramidase activity
CCX79_RS07260	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CCX79_RS07270	COG0436	Aminotransferase
CCX79_RS07275	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CCX79_RS07300	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CCX79_RS07305	COG0358	DNA primase activity
CCX79_RS07315	COG3716	PTS system mannose fructose sorbose family IID component
CCX79_RS07345	COG0758	DNA mediated transformation
CCX79_RS07350	COG0488	(ABC) transporter
CCX79_RS07355	COG0167	dihydroorotate dehydrogenase activity
CCX79_RS07360	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CCX79_RS07365	COG0860	N-Acetylmuramoyl-L-alanine amidase
CCX79_RS07375	COG2183	response to ionizing radiation
CCX79_RS07395	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CCX79_RS07400	COG0626	cystathionine gamma-synthase activity
CCX79_RS07405	COG1045	serine acetyltransferase
CCX79_RS07415	COG0776	regulation of translation
CCX79_RS07420	COG1160	GTP binding
CCX79_RS07425	COG0539	negative regulation of cytoplasmic translation
CCX79_RS07430	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CCX79_RS07440	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CCX79_RS07445	COG1187	pseudouridine synthase activity
CCX79_RS07450	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CCX79_RS07455	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CCX79_RS07465	COG4974	Belongs to the 'phage' integrase family
CCX79_RS07470	COG2996	Protein conserved in bacteria
CCX79_RS07475	COG1610	YqeY-like protein
CCX79_RS07480	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CCX79_RS07485	COG0477	Major facilitator Superfamily
CCX79_RS07490	COG2508	Transcriptional regulator
CCX79_RS07495	COG1113	amino acid transport
CCX79_RS07500	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CCX79_RS07505	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CCX79_RS07510	COG0124	histidyl-tRNA synthetase
CCX79_RS07515	COG2017	converts alpha-aldose to the beta-anomer
CCX79_RS07520	COG2207	Transcriptional regulator
CCX79_RS07525	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CCX79_RS07535	COG0406	alpha-ribazole phosphatase activity
CCX79_RS07540	COG0584	glycerophosphoryl diester phosphodiesterase
CCX79_RS07555	COG1175	transmembrane transport
CCX79_RS07565	COG0667	Aldo Keto reductase
CCX79_RS07570	COG3250	beta-galactosidase activity
CCX79_RS07580	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CCX79_RS07585	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CCX79_RS07595	COG4470	Protein conserved in bacteria
CCX79_RS07600	COG0737	Belongs to the 5'-nucleotidase family
CCX79_RS07610	COG0006	proline dipeptidase activity
CCX79_RS07615	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CCX79_RS07620	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CCX79_RS07655	COG1247	-acetyltransferase
CCX79_RS07660	COG2962	Rard protein
CCX79_RS07685	COG1217	gtp-binding protein TYPA
CCX79_RS07690	COG0483	inositol monophosphate 1-phosphatase activity
CCX79_RS07695	COG4476	Belongs to the UPF0223 family
CCX79_RS07700	COG0242	peptide deformylase activity
CCX79_RS07705	COG0484	heat shock protein binding
CCX79_RS07710	COG0443	Heat shock 70 kDa protein
CCX79_RS07715	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CCX79_RS07720	COG1420	regulation of RNA biosynthetic process
CCX79_RS07725	COG0196	riboflavin kinase activity
CCX79_RS07730	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CCX79_RS07740	COG0436	Aminotransferase
CCX79_RS07745	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CCX79_RS07750	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CCX79_RS07760	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CCX79_RS07765	COG0195	Participates in both transcription termination and antitermination
CCX79_RS07770	COG0779	Required for maturation of 30S ribosomal subunits
CCX79_RS07775	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CCX79_RS07780	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CCX79_RS07785	COG1227	inorganic diphosphatase activity
CCX79_RS07795	COG0187	DNA topoisomerase II activity
CCX79_RS07805	COG1490	D-aminoacyl-tRNA deacylase activity
CCX79_RS07810	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CCX79_RS07830	COG0505	Belongs to the CarA family
CCX79_RS07835	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CCX79_RS07840	COG0564	pseudouridine synthase activity
CCX79_RS07850	COG0328	RNA-DNA hybrid ribonuclease activity
CCX79_RS07860	COG0436	Aminotransferase
CCX79_RS07865	COG0116	Belongs to the methyltransferase superfamily
CCX79_RS07880	COG0017	Asparaginyl-tRNA synthetase
CCX79_RS07895	COG1199	ATP-dependent helicase activity
CCX79_RS07895	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CCX79_RS07915	COG1304	FMN binding
CCX79_RS07925	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CCX79_RS07930	COG2116	formate transmembrane transporter activity
CCX79_RS07935	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CCX79_RS07940	COG0716	FMN binding
CCX79_RS07950	COG1216	Glycosyl transferase, family 2
CCX79_RS07990	COG0463	Glycosyl transferase, family 2
CCX79_RS07995	COG0562	UDP-galactopyranose mutase
CCX79_RS08085	COG1091	dTDP-4-dehydrorhamnose reductase activity
CCX79_RS08090	COG1088	dTDP-glucose 4,6-dehydratase activity
CCX79_RS08100	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CCX79_RS08120	COG1215	transferase activity, transferring glycosyl groups
CCX79_RS08150	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CCX79_RS08155	COG0489	protein tyrosine kinase activity
CCX79_RS08170	COG0024	Methionine aminopeptidase
CCX79_RS08175	COG1316	TRANSCRIPTIONal
CCX79_RS08180	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CCX79_RS08185	COG1114	Component of the transport system for branched-chain amino acids
CCX79_RS08190	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CCX79_RS08195	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CCX79_RS08215	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CCX79_RS08220	COG3142	Participates in the control of copper homeostasis
CCX79_RS08250	COG0165	Argininosuccinate lyase
CCX79_RS08255	COG0137	argininosuccinate synthase activity
CCX79_RS08260	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CCX79_RS08265	COG0217	transcriptional regulatory protein
CCX79_RS08275	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CCX79_RS08280	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CCX79_RS08295	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CCX79_RS08325	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CCX79_RS08330	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CCX79_RS08330	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CCX79_RS08335	COG1234	tRNA 3'-trailer cleavage
CCX79_RS08340	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CCX79_RS08345	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CCX79_RS08350	COG0336	Belongs to the RNA methyltransferase TrmD family
CCX79_RS08355	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CCX79_RS08365	COG1074	ATP-dependent DNA helicase activity
CCX79_RS08370	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
CCX79_RS08385	COG0228	four-way junction DNA binding
CCX79_RS08410	COG0762	integral membrane protein
CCX79_RS08415	COG1799	cell septum assembly
CCX79_RS08430	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CCX79_RS08435	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CCX79_RS08445	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CCX79_RS08450	COG0768	penicillin binding
CCX79_RS08460	COG0275	rRNA processing
CCX79_RS08465	COG2001	Belongs to the MraZ family
CCX79_RS08480	COG1461	Dihydroxyacetone kinase
CCX79_RS08490	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CCX79_RS08495	COG3118	belongs to the thioredoxin family
CCX79_RS08505	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CCX79_RS08510	COG1162	GTPase activity
CCX79_RS08515	COG2815	serine threonine protein kinase
CCX79_RS08515	COG0515	serine threonine protein kinase
CCX79_RS08520	COG0631	protein serine/threonine phosphatase activity
CCX79_RS08525	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CCX79_RS08525	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CCX79_RS08530	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CCX79_RS08535	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CCX79_RS08550	COG3201	nicotinamide mononucleotide transporter
CCX79_RS08555	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CCX79_RS08560	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CCX79_RS08565	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CCX79_RS08575	COG4974	Belongs to the 'phage' integrase family
CCX79_RS08590	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CCX79_RS08595	COG0544	peptidyl-prolyl cis-trans isomerase activity
CCX79_RS08600	COG1335	isochorismatase
CCX79_RS08605	COG0531	amino acid
CCX79_RS08615	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CCX79_RS08625	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CCX79_RS08630	COG0708	Exodeoxyribonuclease III
CCX79_RS08635	COG2176	DNA-directed DNA polymerase activity
CCX79_RS08640	COG0456	acetyltransferase
CCX79_RS08645	COG0802	atpase or kinase
CCX79_RS08680	COG0602	queuosine metabolic process
CCX79_RS08685	COG1328	CTP reductase activity
CCX79_RS08690	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CCX79_RS08695	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CCX79_RS08725	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CCX79_RS08730	COG0140	phosphoribosyl-ATP diphosphatase activity
CCX79_RS08735	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CCX79_RS08740	COG0107	imidazoleglycerol-phosphate synthase activity
CCX79_RS08745	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CCX79_RS08755	COG0131	Imidazoleglycerol-phosphate dehydratase
CCX79_RS08760	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CCX79_RS08775	COG2199	diguanylate cyclase activity
CCX79_RS08775	COG2200	EAL domain
CCX79_RS08780	COG1215	transferase activity, transferring glycosyl groups
CCX79_RS08790	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CCX79_RS08795	COG0561	phosphatase activity
CCX79_RS08805	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CCX79_RS08815	COG0552	protein localization to endoplasmic reticulum
CCX79_RS08820	COG1196	nuclear chromosome segregation
CCX79_RS08825	COG0571	ribonuclease III activity
CCX79_RS08830	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CCX79_RS08850	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CCX79_RS08855	COG0105	UTP biosynthetic process
CCX79_RS08860	COG4807	Protein conserved in bacteria
CCX79_RS08865	COG3237	CsbD-like
CCX79_RS08895	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CCX79_RS08900	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CCX79_RS08905	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CCX79_RS08910	COG1597	lipid kinase activity
CCX79_RS08915	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CCX79_RS08920	COG0154	amidase activity
CCX79_RS08925	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CCX79_RS08930	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CCX79_RS08935	COG0268	Binds directly to 16S ribosomal RNA
CCX79_RS08940	COG0513	Belongs to the DEAD box helicase family
CCX79_RS08945	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CCX79_RS08950	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CCX79_RS08955	COG1466	dna polymerase III delta subunit
CCX79_RS08960	COG2333	competence protein COMEC
CCX79_RS08960	COG0658	competence protein
CCX79_RS08965	COG1596	polysaccharide export
CCX79_RS08965	COG1555	photosystem II stabilization
CCX79_RS08970	COG3480	Lon protease (S16) C-terminal proteolytic domain
CCX79_RS08975	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CCX79_RS08980	COG0742	ribosomal rna small subunit methyltransferase
CCX79_RS08985	COG4471	UPF0298 protein
CCX79_RS08990	COG0772	Belongs to the SEDS family
CCX79_RS08995	COG1363	Peptidase, m42
CCX79_RS09000	COG0588	phosphoglycerate mutase activity
CCX79_RS09005	COG0534	Mate efflux family protein
CCX79_RS09010	COG2252	PERMEase
CCX79_RS09015	COG0497	DNA recombination
CCX79_RS09020	COG1438	arginine binding
CCX79_RS09025	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CCX79_RS09030	COG0142	geranyltranstransferase activity
CCX79_RS09035	COG1722	exodeoxyribonuclease VII activity
CCX79_RS09040	COG1570	exodeoxyribonuclease VII activity
CCX79_RS09055	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CCX79_RS09060	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CCX79_RS09065	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CCX79_RS09070	COG1121	(ABC) transporter
CCX79_RS09080	COG4466	Protein conserved in bacteria
CCX79_RS09085	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CCX79_RS09090	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CCX79_RS09095	COG0084	hydrolase, TatD family'
CCX79_RS09100	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CCX79_RS09105	COG1302	Protein conserved in bacteria
CCX79_RS09110	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CCX79_RS09125	COG1984	allophanate hydrolase subunit 2
CCX79_RS09130	COG0439	Biotin carboxylase
CCX79_RS09135	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CCX79_RS09145	COG2814	Major facilitator Superfamily
CCX79_RS09150	COG0583	DNA-binding transcription factor activity
CCX79_RS09155	COG1063	alcohol dehydrogenase
CCX79_RS09160	COG2814	Major facilitator Superfamily
CCX79_RS09165	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CCX79_RS09170	COG1611	Belongs to the LOG family
CCX79_RS09175	COG5503	Protein of unknown function (DUF1447)
CCX79_RS09385	COG3723	Recombinational DNA repair protein, rece pathway
CCX79_RS09455	COG3152	Membrane
CCX79_RS09465	COG1892	Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four- carbon dicarboxylic acid source for the tricarboxylic acid cycle
CCX79_RS09480	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CCX79_RS09490	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CCX79_RS09495	COG0584	glycerophosphoryl diester phosphodiesterase
CCX79_RS09510	COG4862	establishment of competence for transformation
CCX79_RS09515	COG1393	Belongs to the ArsC family
CCX79_RS09545	COG1098	S1 RNA binding domain
CCX79_RS09555	COG1758	RNA polymerase activity
CCX79_RS09560	COG0194	GDP metabolic process
CCX79_RS09580	COG1193	negative regulation of DNA recombination
CCX79_RS09600	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CCX79_RS09615	COG1418	mRNA catabolic process
CCX79_RS09620	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CCX79_RS09625	COG0557	exoribonuclease II activity
CCX79_RS09635	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CCX79_RS09640	COG0706	membrane insertase activity
CCX79_RS09645	COG1254	Belongs to the acylphosphatase family
CCX79_RS09650	COG5002	protein histidine kinase activity
CCX79_RS09655	COG0745	RESPONSE REGULATOR receiver
CCX79_RS09665	COG1323	Belongs to the UPF0348 family
CCX79_RS09670	COG2226	methyltransferase
CCX79_RS09675	COG0799	negative regulation of ribosome biogenesis
CCX79_RS09680	COG1713	HD superfamily hydrolase involved in NAD metabolism
CCX79_RS09685	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CCX79_RS09690	COG1534	Rna-binding protein
CCX79_RS09695	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CCX79_RS09700	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
CCX79_RS09725	COG1959	2 iron, 2 sulfur cluster binding
CCX79_RS09730	COG0366	Alpha amylase catalytic
CCX79_RS09730	COG5263	repeat protein
CCX79_RS09755	COG5263	repeat protein
CCX79_RS09755	COG0366	Alpha amylase catalytic
CCX79_RS09785	COG2323	membrane
CCX79_RS09795	COG3579	cysteine-type endopeptidase activity
CCX79_RS09800	COG0477	Major facilitator Superfamily
CCX79_RS09810	COG0459	protein refolding
CCX79_RS09815	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CCX79_RS09830	COG3716	PTS system mannose fructose sorbose family IID component
CCX79_RS09835	COG3715	PTS system
CCX79_RS09845	COG1482	cell wall glycoprotein biosynthetic process
CCX79_RS09850	COG0778	Nitroreductase
CCX79_RS09860	COG0561	phosphatase activity
CCX79_RS09870	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CCX79_RS09875	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CCX79_RS09890	COG1214	PFAM Peptidase M22, glycoprotease
CCX79_RS09895	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CCX79_RS09905	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CCX79_RS09910	COG0009	L-threonylcarbamoyladenylate synthase
CCX79_RS09915	COG2890	protein-(glutamine-N5) methyltransferase activity
CCX79_RS09920	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CCX79_RS09925	COG1435	thymidine kinase activity
CCX79_RS09930	COG0791	NLP P60 protein
CCX79_RS09930	COG3883	PFAM NLP P60 protein
CCX79_RS09935	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CCX79_RS09940	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CCX79_RS09945	COG0302	gtp cyclohydrolase
CCX79_RS09950	COG0302	gtp cyclohydrolase
CCX79_RS09950	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CCX79_RS09960	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CCX79_RS09965	COG3442	glutamine amidotransferase
CCX79_RS09970	COG0531	amino acid
CCX79_RS09980	COG0628	permease
CCX79_RS09985	COG2040	homocysteine
CCX79_RS09990	COG0833	amino acid
CCX79_RS09995	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CCX79_RS10000	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CCX79_RS10005	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CCX79_RS10010	COG4166	transmembrane transport
CCX79_RS10015	COG2873	o-acetylhomoserine
CCX79_RS10020	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CCX79_RS10025	COG1854	S-ribosylhomocysteine lyase activity
CCX79_RS10030	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CCX79_RS10035	COG0626	cystathionine gamma-synthase activity
CCX79_RS10040	COG0626	cystathionine gamma-synthase activity
CCX79_RS10045	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
CCX79_RS10050	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CCX79_RS10055	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CCX79_RS10060	COG5002	protein histidine kinase activity
CCX79_RS10065	COG0745	RESPONSE REGULATOR receiver
CCX79_RS10070	COG2337	Toxic component of a toxin-antitoxin (TA) module
CCX79_RS10075	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CCX79_RS10080	COG0736	holo-[acyl-carrier-protein] synthase activity
CCX79_RS10085	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CCX79_RS10090	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CCX79_RS10095	COG1696	Membrane protein involved in D-alanine export
CCX79_RS10100	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CCX79_RS10125	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CCX79_RS10130	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CCX79_RS10135	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CCX79_RS10140	COG0085	RNA polymerase activity