locus-tag	class	description
AZI11_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AZI11_RS00010	COG0592	DNA-directed DNA polymerase activity
AZI11_RS00015	COG2501	S4 domain
AZI11_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AZI11_RS00025	COG0187	DNA topoisomerase II activity
AZI11_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AZI11_RS00035	COG0360	Binds together with S18 to 16S ribosomal RNA
AZI11_RS00040	COG0629	single-stranded DNA binding
AZI11_RS00045	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AZI11_RS00055	COG4166	transmembrane transport
AZI11_RS00070	COG4166	transmembrane transport
AZI11_RS00090	COG0359	binds to the 23S rRNA
AZI11_RS00100	COG2211	Major facilitator Superfamily
AZI11_RS00105	COG3507	Belongs to the glycosyl hydrolase 43 family
AZI11_RS00110	COG0305	Participates in initiation and elongation during chromosome replication
AZI11_RS00115	COG0655	NAD(P)H dehydrogenase (quinone) activity
AZI11_RS00130	COG4166	transmembrane transport
AZI11_RS00150	COG0745	RESPONSE REGULATOR receiver
AZI11_RS00170	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AZI11_RS00175	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AZI11_RS00180	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AZI11_RS00195	COG1983	PspC domain protein
AZI11_RS00300	COG0737	Belongs to the 5'-nucleotidase family
AZI11_RS00315	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AZI11_RS00345	COG0488	(ABC) transporter
AZI11_RS00355	COG0477	Major facilitator Superfamily
AZI11_RS00365	COG1846	Transcriptional regulator
AZI11_RS00375	COG1397	ADP-ribosylglycohydrolase
AZI11_RS00380	COG0110	maltose O-acetyltransferase activity
AZI11_RS00405	COG4166	transmembrane transport
AZI11_RS00420	COG0789	Transcriptional regulator
AZI11_RS00470	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AZI11_RS00495	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AZI11_RS00535	COG0531	amino acid
AZI11_RS00540	COG0076	glutamate decarboxylase activity
AZI11_RS00545	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AZI11_RS00575	COG0450	alkyl hydroperoxide reductase
AZI11_RS00585	COG0702	epimerase
AZI11_RS00615	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AZI11_RS00645	COG2746	aminoglycoside 3-N-acetyltransferase activity
AZI11_RS00660	COG0667	Aldo Keto reductase
AZI11_RS00670	COG2814	Major facilitator Superfamily
AZI11_RS00675	COG2271	Major facilitator Superfamily
AZI11_RS00680	COG2910	NAD(P)H-binding
AZI11_RS00685	COG0477	Major facilitator Superfamily
AZI11_RS00695	COG0778	Nitroreductase
AZI11_RS00705	COG0488	(ABC) transporter
AZI11_RS00710	COG0477	Major facilitator Superfamily
AZI11_RS00720	COG1028	Short-chain dehydrogenase reductase Sdr
AZI11_RS00725	COG1609	Transcriptional regulator
AZI11_RS00730	COG1309	transcriptional regulator
AZI11_RS00735	COG0300	oxidoreductase activity
AZI11_RS00740	COG1253	flavin adenine dinucleotide binding
AZI11_RS00755	COG0531	amino acid
AZI11_RS00760	COG0656	L-ascorbic acid biosynthetic process
AZI11_RS00770	COG0583	DNA-binding transcription factor activity
AZI11_RS00780	COG0656	L-ascorbic acid biosynthetic process
AZI11_RS00800	COG1454	alcohol dehydrogenase
AZI11_RS00800	COG1012	belongs to the aldehyde dehydrogenase family
AZI11_RS00805	COG0791	NLP P60 protein
AZI11_RS00805	COG1388	LysM domain
AZI11_RS00810	COG1388	LysM domain
AZI11_RS00810	COG0791	NLP P60 protein
AZI11_RS00820	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AZI11_RS00845	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
AZI11_RS00850	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AZI11_RS00855	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AZI11_RS00870	COG1131	(ABC) transporter
AZI11_RS00875	COG1418	mRNA catabolic process
AZI11_RS00880	COG0534	Mate efflux family protein
AZI11_RS00885	COG1904	glucuronate isomerase
AZI11_RS00890	COG2211	Major facilitator Superfamily
AZI11_RS00905	COG2610	gluconate transmembrane transporter activity
AZI11_RS00915	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AZI11_RS00920	COG1904	glucuronate isomerase
AZI11_RS00940	COG1312	Catalyzes the dehydration of D-mannonate
AZI11_RS00945	COG0246	Mannitol dehydrogenase
AZI11_RS00955	COG0588	phosphoglycerate mutase activity
AZI11_RS00960	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AZI11_RS00965	COG1070	Carbohydrate kinase
AZI11_RS00970	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
AZI11_RS00980	COG1312	Catalyzes the dehydration of D-mannonate
AZI11_RS00985	COG1609	Transcriptional regulator
AZI11_RS00990	COG2211	Major facilitator Superfamily
AZI11_RS01000	COG1904	glucuronate isomerase
AZI11_RS01015	COG0477	Major facilitator Superfamily
AZI11_RS01040	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AZI11_RS01045	COG2188	Transcriptional regulator
AZI11_RS01055	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AZI11_RS01085	COG0564	pseudouridine synthase activity
AZI11_RS01115	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AZI11_RS01120	COG0601	transmembrane transport
AZI11_RS01125	COG4608	Belongs to the ABC transporter superfamily
AZI11_RS01140	COG0095	Lipoate-protein ligase
AZI11_RS01160	COG2115	Belongs to the xylose isomerase family
AZI11_RS01180	COG5646	InterPro IPR014922
AZI11_RS01195	COG1881	PFAM PEBP family protein
AZI11_RS01215	COG0656	L-ascorbic acid biosynthetic process
AZI11_RS01230	COG1757	Na H antiporter
AZI11_RS01240	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AZI11_RS01245	COG3290	protein histidine kinase activity
AZI11_RS01250	COG4565	transcriptional regulatory protein
AZI11_RS01260	COG1309	transcriptional regulator
AZI11_RS01285	COG3479	Phenolic acid decarboxylase
AZI11_RS01290	COG1695	Transcriptional regulator
AZI11_RS01305	COG2153	protein acetylation
AZI11_RS01310	COG1846	Transcriptional regulator
AZI11_RS01340	COG1914	H( )-stimulated, divalent metal cation uptake system
AZI11_RS01350	COG0516	GMP reductase activity
AZI11_RS01355	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AZI11_RS01360	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AZI11_RS01370	COG1012	belongs to the aldehyde dehydrogenase family
AZI11_RS01380	COG1309	transcriptional regulator
AZI11_RS01390	COG2365	Tyrosine phosphatase family
AZI11_RS01410	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AZI11_RS01440	COG1335	isochorismatase
AZI11_RS01460	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AZI11_RS01465	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AZI11_RS01470	COG0716	FMN binding
AZI11_RS01480	COG1113	amino acid transport
AZI11_RS01505	COG1064	alcohol dehydrogenase
AZI11_RS01515	COG1125	glycine betaine transport
AZI11_RS01515	COG0517	IMP dehydrogenase activity
AZI11_RS01525	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AZI11_RS01540	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AZI11_RS01555	COG0110	maltose O-acetyltransferase activity
AZI11_RS01580	COG1686	Belongs to the peptidase S11 family
AZI11_RS01585	COG0656	L-ascorbic acid biosynthetic process
AZI11_RS01590	COG2217	Heavy metal translocating P-type atpase
AZI11_RS01600	COG0726	polysaccharide deacetylase
AZI11_RS01610	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AZI11_RS01615	COG2755	lipolytic protein G-D-S-L family
AZI11_RS01615	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AZI11_RS01665	COG1942	4-Oxalocrotonate Tautomerase
AZI11_RS01680	COG1174	glycine betaine transport
AZI11_RS01685	COG1732	Glycine betaine
AZI11_RS01715	COG2837	iron assimilation
AZI11_RS01735	COG0463	Glycosyl transferase, family 2
AZI11_RS01750	COG0628	permease
AZI11_RS01755	COG0577	efflux transmembrane transporter activity
AZI11_RS01760	COG1136	(ABC) transporter
AZI11_RS01765	COG0366	Alpha amylase catalytic
AZI11_RS01785	COG0028	Belongs to the TPP enzyme family
AZI11_RS01800	COG5002	protein histidine kinase activity
AZI11_RS01805	COG0745	RESPONSE REGULATOR receiver
AZI11_RS01815	COG0702	epimerase
AZI11_RS01820	COG1252	NADH dehydrogenase
AZI11_RS01825	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AZI11_RS01835	COG1012	belongs to the aldehyde dehydrogenase family
AZI11_RS01840	COG1414	Transcriptional regulator
AZI11_RS01855	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
AZI11_RS01860	COG1028	Short-chain dehydrogenase reductase Sdr
AZI11_RS01870	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AZI11_RS01890	COG1914	H( )-stimulated, divalent metal cation uptake system
AZI11_RS01895	COG1307	EDD domain protein, DegV family
AZI11_RS01900	COG0446	pyridine nucleotide-disulphide oxidoreductase
AZI11_RS01905	COG3118	belongs to the thioredoxin family
AZI11_RS01910	COG1937	Protein conserved in bacteria
AZI11_RS01915	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AZI11_RS01920	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AZI11_RS01930	COG0657	acetylesterase activity
AZI11_RS01935	COG1854	S-ribosylhomocysteine lyase activity
AZI11_RS01945	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AZI11_RS01955	COG0583	DNA-binding transcription factor activity
AZI11_RS01980	COG2357	RelA SpoT domain protein
AZI11_RS02005	COG0745	RESPONSE REGULATOR receiver
AZI11_RS02010	COG5002	protein histidine kinase activity
AZI11_RS02015	COG1609	Transcriptional regulator
AZI11_RS02035	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AZI11_RS02040	COG2017	converts alpha-aldose to the beta-anomer
AZI11_RS02050	COG0561	phosphatase activity
AZI11_RS02065	COG1393	Belongs to the ArsC family
AZI11_RS02070	COG3103	Sh3 type 3 domain protein
AZI11_RS02070	COG1388	LysM domain
AZI11_RS02070	COG0791	NLP P60 protein
AZI11_RS02085	COG0730	response to heat
AZI11_RS02090	COG1028	Short-chain dehydrogenase reductase Sdr
AZI11_RS02095	COG2211	Major facilitator Superfamily
AZI11_RS02105	COG2207	Transcriptional regulator
AZI11_RS02110	COG1028	Short-chain dehydrogenase reductase Sdr
AZI11_RS02120	COG1959	2 iron, 2 sulfur cluster binding
AZI11_RS02125	COG0463	Glycosyl transferase, family 2
AZI11_RS02125	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AZI11_RS02135	COG1733	regulation of RNA biosynthetic process
AZI11_RS02140	COG2814	Major facilitator Superfamily
AZI11_RS02145	COG4989	oxidoreductase activity
AZI11_RS02150	COG1136	(ABC) transporter
AZI11_RS02175	COG2217	Heavy metal translocating P-type atpase
AZI11_RS02205	COG1131	(ABC) transporter
AZI11_RS02230	COG0583	DNA-binding transcription factor activity
AZI11_RS02235	COG2814	Major facilitator Superfamily
AZI11_RS02245	COG0488	(ABC) transporter
AZI11_RS02275	COG3052	prosthetic group binding
AZI11_RS02295	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
AZI11_RS02330	COG1725	Transcriptional regulator
AZI11_RS02335	COG1131	(ABC) transporter
AZI11_RS02345	COG3835	regulator
AZI11_RS02350	COG2610	gluconate transmembrane transporter activity
AZI11_RS02355	COG1929	Belongs to the glycerate kinase type-1 family
AZI11_RS02365	COG3428	Bacterial PH domain
AZI11_RS02410	COG1914	H( )-stimulated, divalent metal cation uptake system
AZI11_RS02420	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AZI11_RS02445	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AZI11_RS02450	COG2323	membrane
AZI11_RS02505	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AZI11_RS02520	COG1609	Transcriptional regulator
AZI11_RS02535	COG3973	AAA domain
AZI11_RS02545	COG0248	Ppx GppA phosphatase
AZI11_RS02560	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AZI11_RS02570	COG1801	Protein of unknown function DUF72
AZI11_RS02575	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AZI11_RS02575	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AZI11_RS02580	COG0084	hydrolase, TatD family'
AZI11_RS02585	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AZI11_RS02590	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AZI11_RS02595	COG4466	Protein conserved in bacteria
AZI11_RS02600	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AZI11_RS02605	COG1573	uracil-dna glycosylase
AZI11_RS02625	COG2723	6-phospho-beta-galactosidase activity
AZI11_RS02630	COG1940	carbohydrate kinase activity
AZI11_RS02655	COG3279	Response regulator of the LytR AlgR family
AZI11_RS02670	COG1121	(ABC) transporter
AZI11_RS02675	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AZI11_RS02685	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AZI11_RS02690	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AZI11_RS02695	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AZI11_RS02710	COG2188	Transcriptional regulator
AZI11_RS02715	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
AZI11_RS02720	COG0561	phosphatase activity
AZI11_RS02725	COG1078	dGTPase activity
AZI11_RS02730	COG0095	Lipoate-protein ligase
AZI11_RS02740	COG3343	RNA polymerase activity
AZI11_RS02745	COG0504	CTP synthase activity
AZI11_RS02765	COG0028	Belongs to the TPP enzyme family
AZI11_RS02770	COG3527	Alpha-acetolactate decarboxylase
AZI11_RS02780	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AZI11_RS02785	COG0254	rRNA binding
AZI11_RS02790	COG3764	Sortase (surface protein transpeptidase)
AZI11_RS02850	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AZI11_RS02855	COG1704	LemA family
AZI11_RS02860	COG0501	Belongs to the peptidase M48B family
AZI11_RS02870	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AZI11_RS02885	COG0736	holo-[acyl-carrier-protein] synthase activity
AZI11_RS02890	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AZI11_RS02900	COG2337	Toxic component of a toxin-antitoxin (TA) module
AZI11_RS02920	COG0193	aminoacyl-tRNA hydrolase activity
AZI11_RS02925	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AZI11_RS02930	COG2244	polysaccharide biosynthetic process
AZI11_RS02935	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AZI11_RS02945	COG1098	S1 RNA binding domain
AZI11_RS02950	COG0037	tRNA processing
AZI11_RS02965	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AZI11_RS02970	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AZI11_RS03015	COG3104	oligopeptide transport
AZI11_RS03035	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AZI11_RS03040	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AZI11_RS03045	COG2188	Transcriptional regulator
AZI11_RS03060	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AZI11_RS03065	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AZI11_RS03075	COG2183	response to ionizing radiation
AZI11_RS03080	COG3091	SprT-like family
AZI11_RS03085	COG0083	homoserine kinase activity
AZI11_RS03120	COG0534	Mate efflux family protein
AZI11_RS03135	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AZI11_RS03135	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AZI11_RS03140	COG3715	PTS system
AZI11_RS03145	COG3716	PTS system mannose fructose sorbose family IID component
AZI11_RS03150	COG0628	permease
AZI11_RS03170	COG1511	domain protein
AZI11_RS03175	COG0803	Belongs to the bacterial solute-binding protein 9 family
AZI11_RS03180	COG1316	TRANSCRIPTIONal
AZI11_RS03190	COG0697	spore germination
AZI11_RS03195	COG0588	phosphoglycerate mutase activity
AZI11_RS03225	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AZI11_RS03235	COG0756	dUTP diphosphatase activity
AZI11_RS03245	COG4956	integral membrane protein (PIN domain superfamily)
AZI11_RS03250	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AZI11_RS03255	COG0215	cysteine-tRNA ligase activity
AZI11_RS03260	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
AZI11_RS03265	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AZI11_RS03270	COG3688	RNA-binding protein containing a PIN domain
AZI11_RS03280	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AZI11_RS03290	COG0250	Participates in transcription elongation, termination and antitermination
AZI11_RS03295	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AZI11_RS03300	COG0081	regulation of translation
AZI11_RS03305	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AZI11_RS03310	COG0222	ribosome binding
AZI11_RS03315	COG0745	RESPONSE REGULATOR receiver
AZI11_RS03320	COG5002	protein histidine kinase activity
AZI11_RS03325	COG0463	Glycosyl transferase, family 2
AZI11_RS03340	COG0392	lysyltransferase activity
AZI11_RS03340	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AZI11_RS03350	COG1250	3-hydroxyacyl-CoA dehydrogenase
AZI11_RS03355	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AZI11_RS03365	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AZI11_RS03370	COG2813	Specifically methylates the guanine in position
AZI11_RS03385	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AZI11_RS03390	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AZI11_RS03395	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AZI11_RS03405	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AZI11_RS03410	COG3870	Protein conserved in bacteria
AZI11_RS03415	COG0470	DNA polymerase III
AZI11_RS03420	COG4467	Involved in initiation control of chromosome replication
AZI11_RS03435	COG1214	PFAM Peptidase M22, glycoprotease
AZI11_RS03445	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AZI11_RS03450	COG2807	transmembrane transport
AZI11_RS03455	COG0640	Transcriptional regulator
AZI11_RS03460	COG0488	(ABC) transporter
AZI11_RS03465	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
AZI11_RS03470	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AZI11_RS03475	COG0459	protein refolding
AZI11_RS03480	COG0531	amino acid
AZI11_RS03485	COG1346	cytolysis
AZI11_RS03495	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AZI11_RS03500	COG1739	Uncharacterized protein family UPF0029
AZI11_RS03505	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
AZI11_RS03520	COG0653	protein targeting
AZI11_RS03535	COG0745	RESPONSE REGULATOR receiver
AZI11_RS03540	COG5002	protein histidine kinase activity
AZI11_RS03550	COG0573	inorganic phosphate transmembrane transporter activity
AZI11_RS03555	COG0581	inorganic phosphate transmembrane transporter activity
AZI11_RS03560	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AZI11_RS03565	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AZI11_RS03570	COG0704	Plays a role in the regulation of phosphate uptake
AZI11_RS03575	COG1983	PspC domain protein
AZI11_RS03585	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AZI11_RS03590	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AZI11_RS03595	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AZI11_RS03600	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AZI11_RS03605	COG0492	ferredoxin-NADP+ reductase activity
AZI11_RS03620	COG0556	nucleotide-excision repair
AZI11_RS03625	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AZI11_RS03635	COG1660	Displays ATPase and GTPase activities
AZI11_RS03640	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AZI11_RS03645	COG1481	regulation of sporulation
AZI11_RS03650	COG0740	serine-type endopeptidase activity
AZI11_RS03670	COG4684	Psort location CytoplasmicMembrane, score
AZI11_RS03690	COG0126	phosphoglycerate kinase activity
AZI11_RS03695	COG0149	triose-phosphate isomerase activity
AZI11_RS03700	COG0148	phosphopyruvate hydratase activity
AZI11_RS03715	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AZI11_RS03725	COG0557	exoribonuclease II activity
AZI11_RS03730	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AZI11_RS03745	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AZI11_RS03750	COG0280	phosphate acetyltransferase
AZI11_RS03755	COG0802	atpase or kinase
AZI11_RS03765	COG0667	Aldo Keto reductase
AZI11_RS03775	COG0708	Exodeoxyribonuclease III
AZI11_RS03780	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AZI11_RS03785	COG0025	NhaP-type Na H and K H
AZI11_RS03795	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AZI11_RS03805	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AZI11_RS03810	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AZI11_RS03815	COG0363	glucosamine-6-phosphate deaminase activity
AZI11_RS03820	COG1388	LysM domain
AZI11_RS03820	COG1705	Flagellar rod assembly protein muramidase FlgJ
AZI11_RS03845	COG1134	teichoic acid transport
AZI11_RS03880	COG1120	ATPase activity
AZI11_RS03885	COG0248	Ppx GppA phosphatase
AZI11_RS03890	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AZI11_RS03900	COG3475	LICD family
AZI11_RS03925	COG3759	membrane
AZI11_RS03935	COG0114	fumarate hydratase activity
AZI11_RS03955	COG1609	Transcriptional regulator
AZI11_RS03975	COG2235	arginine
AZI11_RS04055	COG0745	RESPONSE REGULATOR receiver
AZI11_RS04060	COG5002	protein histidine kinase activity
AZI11_RS04060	COG3850	Histidine kinase
AZI11_RS04065	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AZI11_RS04070	COG4975	Glucose uptake
AZI11_RS04075	COG0166	Belongs to the GPI family
AZI11_RS04085	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
AZI11_RS04140	COG1396	sequence-specific DNA binding
AZI11_RS04190	COG3617	BRO family, N-terminal domain
AZI11_RS04235	COG0589	response to stress
AZI11_RS04255	COG5484	DNA packaging
AZI11_RS04260	COG1783	phage Terminase large subunit
AZI11_RS04335	COG5412	phage tail tape measure protein
AZI11_RS04335	COG3953	SLT domain
AZI11_RS04440	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AZI11_RS04445	COG2203	Gaf domain
AZI11_RS04445	COG5001	Diguanylate cyclase
AZI11_RS04445	COG4251	negative regulation of phosphorylation
AZI11_RS04445	COG3706	GGDEF domain
AZI11_RS04480	COG3442	glutamine amidotransferase
AZI11_RS04485	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AZI11_RS04490	COG1435	thymidine kinase activity
AZI11_RS04495	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AZI11_RS04500	COG2890	protein-(glutamine-N5) methyltransferase activity
AZI11_RS04505	COG0009	L-threonylcarbamoyladenylate synthase
AZI11_RS04510	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AZI11_RS04515	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AZI11_RS04520	COG0356	it plays a direct role in the translocation of protons across the membrane
AZI11_RS04525	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AZI11_RS04530	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AZI11_RS04535	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AZI11_RS04540	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AZI11_RS04555	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AZI11_RS04565	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AZI11_RS04570	COG1077	Cell shape determining protein MreB Mrl
AZI11_RS04575	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AZI11_RS04585	COG0772	Belongs to the SEDS family
AZI11_RS04590	COG0509	glycine decarboxylation via glycine cleavage system
AZI11_RS04605	COG1181	Belongs to the D-alanine--D-alanine ligase family
AZI11_RS04620	COG0589	response to stress
AZI11_RS04630	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AZI11_RS04640	COG4493	Belongs to the UPF0637 family
AZI11_RS04650	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AZI11_RS04655	COG1956	GAF domain-containing protein
AZI11_RS04660	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
AZI11_RS04665	COG1104	cysteine desulfurase activity
AZI11_RS04670	COG0301	tRNA thio-modification
AZI11_RS04680	COG0525	valine-tRNA ligase activity
AZI11_RS04685	COG0285	dihydrofolate synthase activity
AZI11_RS04690	COG2003	Belongs to the UPF0758 family
AZI11_RS04695	COG1077	Cell shape determining protein MreB Mrl
AZI11_RS04700	COG1792	Involved in formation and maintenance of cell shape
AZI11_RS04710	COG0850	regulation of cytokinetic process
AZI11_RS04715	COG2894	cell division
AZI11_RS04720	COG0765	amino acid transport
AZI11_RS04725	COG1126	abc transporter atp-binding protein
AZI11_RS04730	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZI11_RS04735	COG0612	Peptidase, M16
AZI11_RS04740	COG0612	Peptidase, M16
AZI11_RS04745	COG1426	Protein conserved in bacteria
AZI11_RS04750	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AZI11_RS04755	COG1546	Belongs to the CinA family
AZI11_RS04755	COG1058	Belongs to the CinA family
AZI11_RS04760	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AZI11_RS04765	COG1418	mRNA catabolic process
AZI11_RS04770	COG1692	metallophosphoesterase
AZI11_RS04775	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AZI11_RS04780	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AZI11_RS04785	COG0632	four-way junction helicase activity
AZI11_RS04790	COG2255	four-way junction helicase activity
AZI11_RS04795	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AZI11_RS04800	COG0343	queuine tRNA-ribosyltransferase activity
AZI11_RS04810	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AZI11_RS04815	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AZI11_RS04820	COG0513	Belongs to the DEAD box helicase family
AZI11_RS04825	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AZI11_RS04830	COG4472	Bacterial protein of unknown function (DUF965)
AZI11_RS04835	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AZI11_RS04840	COG3906	Belongs to the UPF0473 family
AZI11_RS04855	COG1193	negative regulation of DNA recombination
AZI11_RS04860	COG3118	belongs to the thioredoxin family
AZI11_RS04865	COG1719	4-vinyl reductase, 4VR
AZI11_RS04870	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AZI11_RS04875	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AZI11_RS04885	COG0517	IMP dehydrogenase activity
AZI11_RS04925	COG0668	transmembrane transport
AZI11_RS04940	COG0006	proline dipeptidase activity
AZI11_RS04945	COG1609	Transcriptional regulator
AZI11_RS04955	COG1126	abc transporter atp-binding protein
AZI11_RS04960	COG0765	amino acid transport
AZI11_RS04965	COG0217	transcriptional regulatory protein
AZI11_RS04970	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AZI11_RS04975	COG1459	type II secretion system
AZI11_RS04980	COG4537	Required for transformation and DNA binding
AZI11_RS05005	COG0827	DNA restriction-modification system
AZI11_RS05015	COG1113	amino acid transport
AZI11_RS05020	COG0656	L-ascorbic acid biosynthetic process
AZI11_RS05030	COG0737	Belongs to the 5'-nucleotidase family
AZI11_RS05035	COG4470	Protein conserved in bacteria
AZI11_RS05065	COG0531	amino acid
AZI11_RS05070	COG1028	Short-chain dehydrogenase reductase Sdr
AZI11_RS05075	COG0656	L-ascorbic acid biosynthetic process
AZI11_RS05080	COG0300	oxidoreductase activity
AZI11_RS05085	COG0789	Transcriptional regulator
AZI11_RS05090	COG0586	Pfam SNARE associated Golgi protein
AZI11_RS05095	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AZI11_RS05100	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AZI11_RS05105	COG0539	negative regulation of cytoplasmic translation
AZI11_RS05225	COG1234	tRNA 3'-trailer cleavage
AZI11_RS05230	COG1393	Belongs to the ArsC family
AZI11_RS05235	COG4862	establishment of competence for transformation
AZI11_RS05250	COG1215	transferase activity, transferring glycosyl groups
AZI11_RS05260	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
AZI11_RS05265	COG0671	phosphoesterase, PA-phosphatase related
AZI11_RS05270	COG0495	leucyl-tRNA aminoacylation
AZI11_RS05280	COG1129	ABC transporter
AZI11_RS05295	COG2244	polysaccharide biosynthetic process
AZI11_RS05300	COG1187	pseudouridine synthase activity
AZI11_RS05305	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AZI11_RS05315	COG0589	response to stress
AZI11_RS05325	COG1113	amino acid transport
AZI11_RS05335	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AZI11_RS05340	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AZI11_RS05345	COG1674	ftsk spoiiie
AZI11_RS05350	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AZI11_RS05370	COG0402	S-adenosylhomocysteine deaminase activity
AZI11_RS05375	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AZI11_RS05375	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AZI11_RS05380	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AZI11_RS05385	COG0237	dephospho-CoA kinase activity
AZI11_RS05390	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AZI11_RS05400	COG1484	DNA-dependent DNA replication
AZI11_RS05405	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AZI11_RS05410	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AZI11_RS05415	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AZI11_RS05420	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AZI11_RS05425	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
AZI11_RS05430	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AZI11_RS05440	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AZI11_RS05445	COG1713	HD superfamily hydrolase involved in NAD metabolism
AZI11_RS05450	COG0799	negative regulation of ribosome biogenesis
AZI11_RS05455	COG2226	methyltransferase
AZI11_RS05460	COG1323	Belongs to the UPF0348 family
AZI11_RS05470	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AZI11_RS05475	COG0561	phosphatase activity
AZI11_RS05480	COG0640	Transcriptional regulator
AZI11_RS05485	COG5549	protein import
AZI11_RS05485	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AZI11_RS05490	COG1064	alcohol dehydrogenase
AZI11_RS05495	COG0745	RESPONSE REGULATOR receiver
AZI11_RS05500	COG5002	protein histidine kinase activity
AZI11_RS05510	COG0706	membrane insertase activity
AZI11_RS05515	COG1254	Belongs to the acylphosphatase family
AZI11_RS05520	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AZI11_RS05530	COG1733	regulation of RNA biosynthetic process
AZI11_RS05535	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AZI11_RS05540	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AZI11_RS05540	COG0072	phenylalanine-tRNA ligase activity
AZI11_RS05545	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AZI11_RS05550	COG0572	uridine kinase
AZI11_RS05555	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AZI11_RS05570	COG2155	Conserved Protein
AZI11_RS05575	COG0768	penicillin binding
AZI11_RS05580	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AZI11_RS05585	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AZI11_RS05590	COG0705	Rhomboid family
AZI11_RS05590	COG0457	Tetratricopeptide repeat
AZI11_RS05600	COG1940	carbohydrate kinase activity
AZI11_RS05615	COG0584	glycerophosphoryl diester phosphodiesterase
AZI11_RS05625	COG0789	Transcriptional regulator
AZI11_RS05655	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AZI11_RS05660	COG2868	ribosomal protein
AZI11_RS05665	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AZI11_RS05670	COG0006	proline dipeptidase activity
AZI11_RS05675	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AZI11_RS05680	COG1302	Protein conserved in bacteria
AZI11_RS05685	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AZI11_RS05690	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AZI11_RS05695	COG1570	exodeoxyribonuclease VII activity
AZI11_RS05700	COG1722	exodeoxyribonuclease VII activity
AZI11_RS05710	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
AZI11_RS05715	COG1438	arginine binding
AZI11_RS05720	COG0497	DNA recombination
AZI11_RS05735	COG0194	GDP metabolic process
AZI11_RS05740	COG1758	RNA polymerase activity
AZI11_RS05745	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AZI11_RS05750	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AZI11_RS05755	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AZI11_RS05760	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AZI11_RS05760	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AZI11_RS05765	COG0631	protein serine/threonine phosphatase activity
AZI11_RS05770	COG2815	serine threonine protein kinase
AZI11_RS05770	COG0515	serine threonine protein kinase
AZI11_RS05775	COG1162	GTPase activity
AZI11_RS05780	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AZI11_RS05785	COG1564	THIamine pyrophosphokinase
AZI11_RS05790	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AZI11_RS05795	COG1302	Protein conserved in bacteria
AZI11_RS05800	COG1461	Dihydroxyacetone kinase
AZI11_RS05805	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AZI11_RS05810	COG0416	fatty acid biosynthetic process
AZI11_RS05815	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AZI11_RS05820	COG0571	ribonuclease III activity
AZI11_RS05825	COG1196	nuclear chromosome segregation
AZI11_RS05835	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
AZI11_RS05840	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AZI11_RS05865	COG0228	four-way junction DNA binding
AZI11_RS05870	COG1837	Belongs to the UPF0109 family
AZI11_RS05875	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AZI11_RS05880	COG0336	Belongs to the RNA methyltransferase TrmD family
AZI11_RS05885	COG0335	large ribosomal subunit rRNA binding
AZI11_RS05895	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AZI11_RS05905	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AZI11_RS05910	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AZI11_RS05920	COG1028	Short-chain dehydrogenase reductase Sdr
AZI11_RS05930	COG0511	ligase activity, forming carbon-carbon bonds
AZI11_RS05935	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AZI11_RS05940	COG0439	Biotin carboxylase
AZI11_RS05945	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AZI11_RS05950	COG0825	malonyl-CoA metabolic process
AZI11_RS05955	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AZI11_RS05965	COG1268	BioY protein
AZI11_RS05970	COG1694	Mazg nucleotide pyrophosphohydrolase
AZI11_RS05980	COG1028	Short-chain dehydrogenase reductase Sdr
AZI11_RS05985	COG0789	Transcriptional regulator
AZI11_RS05995	COG2814	Major facilitator Superfamily
AZI11_RS06020	COG2814	Major facilitator Superfamily
AZI11_RS06025	COG1598	PFAM Uncharacterised protein family UPF0150
AZI11_RS06030	COG0789	Transcriptional regulator
AZI11_RS06035	COG0667	Aldo Keto reductase
AZI11_RS06045	COG1214	PFAM Peptidase M22, glycoprotease
AZI11_RS06045	COG0456	acetyltransferase
AZI11_RS06065	COG0446	pyridine nucleotide-disulphide oxidoreductase
AZI11_RS06090	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AZI11_RS06095	COG1942	4-Oxalocrotonate Tautomerase
AZI11_RS06100	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AZI11_RS06115	COG3655	Transcriptional regulator
AZI11_RS06130	COG1215	transferase activity, transferring glycosyl groups
AZI11_RS06145	COG0577	efflux transmembrane transporter activity
AZI11_RS06145	COG1136	(ABC) transporter
AZI11_RS06155	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AZI11_RS06190	COG1309	transcriptional regulator
AZI11_RS06195	COG1304	FMN binding
AZI11_RS06205	COG0025	NhaP-type Na H and K H
AZI11_RS06210	COG2807	transmembrane transport
AZI11_RS06215	COG3158	transport of potassium into the cell
AZI11_RS06230	COG0789	Transcriptional regulator
AZI11_RS06250	COG0583	DNA-binding transcription factor activity
AZI11_RS06270	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AZI11_RS06280	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
AZI11_RS06280	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AZI11_RS06285	COG1304	FMN binding
AZI11_RS06305	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AZI11_RS06305	COG1199	ATP-dependent helicase activity
AZI11_RS06335	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AZI11_RS06340	COG3331	DNA recombination
AZI11_RS06350	COG3599	regulation of cell shape
AZI11_RS06360	COG0116	Belongs to the methyltransferase superfamily
AZI11_RS06370	COG0004	ammonium transporteR
AZI11_RS06405	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AZI11_RS06420	COG2759	Belongs to the formate--tetrahydrofolate ligase family
AZI11_RS06425	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AZI11_RS06430	COG0564	pseudouridine synthase activity
AZI11_RS06435	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AZI11_RS06450	COG1293	RNA-binding protein homologous to eukaryotic snRNP
AZI11_RS06455	COG1846	Transcriptional regulator
AZI11_RS06465	COG2270	Major facilitator Superfamily
AZI11_RS06470	COG1307	EDD domain protein, DegV family
AZI11_RS06475	COG4720	Psort location CytoplasmicMembrane, score
AZI11_RS06480	COG2246	polysaccharide biosynthetic process
AZI11_RS06545	COG0300	oxidoreductase activity
AZI11_RS06565	COG4221	oxidoreductase activity
AZI11_RS06570	COG0583	DNA-binding transcription factor activity
AZI11_RS06575	COG0583	DNA-binding transcription factor activity
AZI11_RS06580	COG4221	oxidoreductase activity
AZI11_RS06605	COG1309	transcriptional regulator
AZI11_RS06610	COG4974	Belongs to the 'phage' integrase family
AZI11_RS06625	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AZI11_RS06635	COG1227	inorganic diphosphatase activity
AZI11_RS06640	COG0583	DNA-binding transcription factor activity
AZI11_RS06650	COG0187	DNA topoisomerase II activity
AZI11_RS06655	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AZI11_RS06665	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AZI11_RS06670	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AZI11_RS06680	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AZI11_RS06685	COG0758	DNA mediated transformation
AZI11_RS06690	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AZI11_RS06695	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AZI11_RS06785	COG1070	Carbohydrate kinase
AZI11_RS06800	COG4479	Belongs to the UPF0346 family
AZI11_RS06810	COG2755	lipolytic protein G-D-S-L family
AZI11_RS06815	COG1307	EDD domain protein, DegV family
AZI11_RS06820	COG1272	protein, Hemolysin III
AZI11_RS06825	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AZI11_RS06830	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AZI11_RS06835	COG0488	(ABC) transporter
AZI11_RS06840	COG0617	tRNA 3'-terminal CCA addition
AZI11_RS06845	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AZI11_RS06850	COG0457	Tetratricopeptide repeat
AZI11_RS06860	COG1160	GTP binding
AZI11_RS06865	COG0539	negative regulation of cytoplasmic translation
AZI11_RS06870	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AZI11_RS06875	COG1705	Flagellar rod assembly protein muramidase FlgJ
AZI11_RS06875	COG1388	LysM domain
AZI11_RS06880	COG0514	ATP-dependent DNA helicase (RecQ)
AZI11_RS06890	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
AZI11_RS06895	COG1187	pseudouridine synthase activity
AZI11_RS06900	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AZI11_RS06905	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AZI11_RS06920	COG2996	Protein conserved in bacteria
AZI11_RS06935	COG0587	DNA-directed DNA polymerase activity
AZI11_RS06940	COG0542	response to heat
AZI11_RS06950	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AZI11_RS06955	COG2384	SAM-dependent methyltransferase
AZI11_RS06960	COG1033	growth of symbiont in host cell
AZI11_RS06960	COG2409	Drug exporters of the RND superfamily
AZI11_RS06965	COG1959	2 iron, 2 sulfur cluster binding
AZI11_RS06970	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AZI11_RS06975	COG0358	DNA primase activity
AZI11_RS06980	COG0751	glycine-tRNA ligase activity
AZI11_RS06985	COG0752	glycyl-tRNA synthetase alpha subunit
AZI11_RS06990	COG1381	Involved in DNA repair and RecF pathway recombination
AZI11_RS06995	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AZI11_RS07000	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AZI11_RS07005	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AZI11_RS07010	COG1702	phosphate starvation-inducible protein PhoH
AZI11_RS07015	COG1610	YqeY-like protein
AZI11_RS07020	COG1733	regulation of RNA biosynthetic process
AZI11_RS07030	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AZI11_RS07035	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AZI11_RS07040	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
AZI11_RS07045	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AZI11_RS07050	COG1682	transport, permease protein
AZI11_RS07060	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AZI11_RS07065	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AZI11_RS07070	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AZI11_RS07075	COG0124	histidyl-tRNA synthetase
AZI11_RS07085	COG0860	N-Acetylmuramoyl-L-alanine amidase
AZI11_RS07090	COG3001	Fructosamine kinase
AZI11_RS07100	COG1490	D-aminoacyl-tRNA deacylase activity
AZI11_RS07105	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AZI11_RS07115	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AZI11_RS07120	COG2264	protein methyltransferase activity
AZI11_RS07130	COG1970	mechanosensitive ion channel activity
AZI11_RS07145	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AZI11_RS07165	COG0481	GTPase activity
AZI11_RS07170	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
AZI11_RS07175	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AZI11_RS07180	COG1696	Membrane protein involved in D-alanine export
AZI11_RS07185	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AZI11_RS07195	COG0484	heat shock protein binding
AZI11_RS07200	COG0443	Heat shock 70 kDa protein
AZI11_RS07205	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AZI11_RS07210	COG1420	regulation of RNA biosynthetic process
AZI11_RS07215	COG0196	riboflavin kinase activity
AZI11_RS07220	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AZI11_RS07225	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AZI11_RS07230	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AZI11_RS07240	COG2740	Nucleic-acid-binding protein implicated in transcription termination
AZI11_RS07245	COG0195	Participates in both transcription termination and antitermination
AZI11_RS07250	COG0779	Required for maturation of 30S ribosomal subunits
AZI11_RS07260	COG2176	DNA-directed DNA polymerase activity
AZI11_RS07265	COG0442	prolyl-tRNA aminoacylation
AZI11_RS07270	COG0750	zinc metalloprotease
AZI11_RS07275	COG4589	Belongs to the CDS family
AZI11_RS07280	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AZI11_RS07295	COG0528	UMP kinase activity
AZI11_RS07300	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AZI11_RS07305	COG0052	Belongs to the universal ribosomal protein uS2 family
AZI11_RS07315	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AZI11_RS07320	COG2827	Endonuclease containing a URI domain
AZI11_RS07325	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AZI11_RS07330	COG0204	Acyl-transferase
AZI11_RS07335	COG1132	(ABC) transporter
AZI11_RS07340	COG1132	(ABC) transporter
AZI11_RS07345	COG3763	UPF0154 protein
AZI11_RS07350	COG4224	UPF0291 protein
AZI11_RS07355	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AZI11_RS07370	COG3425	synthase
AZI11_RS07375	COG2326	polyphosphate kinase activity
AZI11_RS07390	COG0105	UTP biosynthetic process
AZI11_RS07415	COG1597	lipid kinase activity
AZI11_RS07430	COG0589	response to stress
AZI11_RS07435	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AZI11_RS07440	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AZI11_RS07440	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AZI11_RS07445	COG5416	Lipopolysaccharide assembly protein A domain
AZI11_RS07450	COG1234	tRNA 3'-trailer cleavage
AZI11_RS07465	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AZI11_RS07470	COG0322	excinuclease ABC activity
AZI11_RS07485	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AZI11_RS07490	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AZI11_RS07495	COG0544	peptidyl-prolyl cis-trans isomerase activity
AZI11_RS07500	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AZI11_RS07515	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AZI11_RS07520	COG0268	Binds directly to 16S ribosomal RNA
AZI11_RS07530	COG1309	transcriptional regulator
AZI11_RS07535	COG1466	dna polymerase III delta subunit
AZI11_RS07540	COG0658	competence protein
AZI11_RS07540	COG2333	competence protein COMEC
AZI11_RS07545	COG2131	deaminase
AZI11_RS07550	COG1555	photosystem II stabilization
AZI11_RS07550	COG1596	polysaccharide export
AZI11_RS07555	COG3480	Lon protease (S16) C-terminal proteolytic domain
AZI11_RS07560	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AZI11_RS07565	COG0742	ribosomal rna small subunit methyltransferase
AZI11_RS07570	COG4471	UPF0298 protein
AZI11_RS07575	COG0772	Belongs to the SEDS family
AZI11_RS07580	COG1217	gtp-binding protein TYPA
AZI11_RS07585	COG0483	inositol monophosphate 1-phosphatase activity
AZI11_RS07590	COG4476	Belongs to the UPF0223 family
AZI11_RS07615	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AZI11_RS07620	COG0242	peptide deformylase activity
AZI11_RS07630	COG5503	Protein of unknown function (DUF1447)
AZI11_RS07635	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AZI11_RS07640	COG1597	lipid kinase activity
AZI11_RS07650	COG0791	NLP P60 protein
AZI11_RS07650	COG1388	LysM domain
AZI11_RS07675	COG1609	Transcriptional regulator
AZI11_RS07680	COG0667	Aldo Keto reductase
AZI11_RS07685	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AZI11_RS07690	COG4166	transmembrane transport
AZI11_RS07700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZI11_RS07705	COG0765	amino acid transport
AZI11_RS07715	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AZI11_RS07720	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AZI11_RS07735	COG0482	sulfurtransferase activity
AZI11_RS07745	COG1104	cysteine desulfurase activity
AZI11_RS07750	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AZI11_RS07760	COG0494	nUDIX hydrolase
AZI11_RS07765	COG1278	Cold shock
AZI11_RS07770	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AZI11_RS07775	COG3599	regulation of cell shape
AZI11_RS07790	COG1799	cell septum assembly
AZI11_RS07795	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AZI11_RS07805	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AZI11_RS07810	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AZI11_RS07815	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AZI11_RS07820	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AZI11_RS07825	COG0768	penicillin binding
AZI11_RS07835	COG0275	rRNA processing
AZI11_RS07840	COG2001	Belongs to the MraZ family
AZI11_RS07855	COG1674	ftsk spoiiie
AZI11_RS07860	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AZI11_RS07870	COG0628	permease
AZI11_RS07875	COG3142	Participates in the control of copper homeostasis
AZI11_RS07915	COG0564	pseudouridine synthase activity
AZI11_RS07920	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AZI11_RS07925	COG2357	RelA SpoT domain protein
AZI11_RS07935	COG1307	EDD domain protein, DegV family
AZI11_RS07950	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AZI11_RS07955	COG0510	thiamine kinase activity
AZI11_RS07965	COG1131	(ABC) transporter
AZI11_RS07970	COG0537	adenosine 5'-monophosphoramidase activity
AZI11_RS07980	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AZI11_RS07990	COG4717	serine-type aminopeptidase activity
AZI11_RS07995	COG0420	3'-5' exonuclease activity
AZI11_RS08000	COG3679	Belongs to the UPF0342 family
AZI11_RS08005	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AZI11_RS08010	COG1438	arginine binding
AZI11_RS08015	COG0018	arginyl-trna synthetase
AZI11_RS08030	COG5632	N-Acetylmuramoyl-L-alanine amidase
AZI11_RS08030	COG4193	domain, Protein
AZI11_RS08030	COG3266	domain, Protein
AZI11_RS08070	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AZI11_RS08070	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AZI11_RS08075	COG1794	racemase activity, acting on amino acids and derivatives
AZI11_RS08085	COG0367	asparagine synthase
AZI11_RS08140	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AZI11_RS08275	COG5484	DNA packaging
AZI11_RS08375	COG3646	Phage regulatory protein
AZI11_RS08395	COG1396	sequence-specific DNA binding
AZI11_RS08420	COG1970	mechanosensitive ion channel activity
AZI11_RS08465	COG1846	Transcriptional regulator
AZI11_RS08480	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AZI11_RS08485	COG1554	hydrolase, family 65, central catalytic
AZI11_RS08490	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AZI11_RS08500	COG1428	Deoxynucleoside kinase
AZI11_RS08510	COG0477	Major facilitator Superfamily
AZI11_RS08515	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AZI11_RS08535	COG0393	Putative heavy-metal-binding
AZI11_RS08630	COG1368	sulfuric ester hydrolase activity
AZI11_RS08645	COG0438	transferase activity, transferring glycosyl groups
AZI11_RS08650	COG0438	transferase activity, transferring glycosyl groups
AZI11_RS08655	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AZI11_RS08670	COG0542	response to heat
AZI11_RS08690	COG0446	pyridine nucleotide-disulphide oxidoreductase
AZI11_RS08700	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AZI11_RS08710	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AZI11_RS08720	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AZI11_RS08725	COG0628	permease
AZI11_RS08730	COG3557	Belongs to the UPF0374 family
AZI11_RS08745	COG2137	regulation of response to DNA damage stimulus
AZI11_RS08755	COG1295	ribonuclease BN
AZI11_RS08765	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AZI11_RS08770	COG0463	Glycosyl transferase, family 2
AZI11_RS08775	COG2610	gluconate transmembrane transporter activity
AZI11_RS08795	COG0513	Belongs to the DEAD box helicase family
AZI11_RS08820	COG1070	Carbohydrate kinase
AZI11_RS08830	COG0531	amino acid
AZI11_RS08835	COG0738	Major facilitator superfamily
AZI11_RS08840	COG1869	D-ribose catabolic process
AZI11_RS08845	COG1181	Belongs to the D-alanine--D-alanine ligase family
AZI11_RS08845	COG2918	glutathione biosynthetic process
AZI11_RS08855	COG2390	Transcriptional regulator
AZI11_RS08860	COG0813	purine-nucleoside phosphorylase activity
AZI11_RS08865	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
AZI11_RS08870	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AZI11_RS08885	COG2365	Tyrosine phosphatase family
AZI11_RS08890	COG1902	pentaerythritol trinitrate reductase activity
AZI11_RS08910	COG1012	belongs to the aldehyde dehydrogenase family
AZI11_RS08925	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
AZI11_RS08935	COG4869	propanediol catabolic process
AZI11_RS08990	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AZI11_RS09000	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AZI11_RS09005	COG1597	lipid kinase activity
AZI11_RS09010	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AZI11_RS09015	COG0154	amidase activity
AZI11_RS09020	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AZI11_RS09025	COG4851	CamS sex pheromone cAM373 precursor
AZI11_RS09030	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AZI11_RS09040	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AZI11_RS09045	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AZI11_RS09060	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AZI11_RS09065	COG4988	ABC transporter
AZI11_RS09070	COG1294	oxidase, subunit
AZI11_RS09075	COG1271	oxidase subunit
AZI11_RS09115	COG2244	polysaccharide biosynthetic process
AZI11_RS09120	COG0562	UDP-galactopyranose mutase
AZI11_RS09125	COG0463	Glycosyl transferase, family 2
AZI11_RS09125	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AZI11_RS09135	COG1215	transferase activity, transferring glycosyl groups
AZI11_RS09145	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AZI11_RS09150	COG4464	protein tyrosine phosphatase activity
AZI11_RS09155	COG0489	protein tyrosine kinase activity
AZI11_RS09165	COG1316	TRANSCRIPTIONal
AZI11_RS09170	COG0095	Lipoate-protein ligase
AZI11_RS09175	COG0531	amino acid
AZI11_RS09180	COG2502	aspartate--ammonia ligase
AZI11_RS09185	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AZI11_RS09195	COG0307	riboflavin synthase, alpha
AZI11_RS09200	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AZI11_RS09200	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AZI11_RS09205	COG0569	domain protein
AZI11_RS09210	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AZI11_RS09215	COG1482	cell wall glycoprotein biosynthetic process
AZI11_RS09220	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AZI11_RS09225	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AZI11_RS09230	COG0101	tRNA pseudouridine synthase activity
AZI11_RS09235	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AZI11_RS09240	COG1122	ATPase activity
AZI11_RS09245	COG1122	ATPase activity
AZI11_RS09250	COG0203	ribosomal protein L17
AZI11_RS09255	COG0202	RNA polymerase activity
AZI11_RS09260	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AZI11_RS09265	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AZI11_RS09270	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AZI11_RS09275	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AZI11_RS09290	COG0200	Binds to the 23S rRNA
AZI11_RS09295	COG1841	ribosomal large subunit assembly
AZI11_RS09300	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AZI11_RS09305	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AZI11_RS09310	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AZI11_RS09315	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AZI11_RS09320	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AZI11_RS09325	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AZI11_RS09330	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AZI11_RS09335	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AZI11_RS09340	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AZI11_RS09345	COG0255	Belongs to the universal ribosomal protein uL29 family
AZI11_RS09350	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AZI11_RS09355	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AZI11_RS09360	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AZI11_RS09365	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AZI11_RS09370	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AZI11_RS09375	COG0089	rRNA binding
AZI11_RS09380	COG0088	Forms part of the polypeptide exit tunnel
AZI11_RS09385	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AZI11_RS09390	COG0051	transcription antitermination factor activity, RNA binding
AZI11_RS09400	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AZI11_RS09405	COG0049	tRNA binding
AZI11_RS09410	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AZI11_RS09420	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AZI11_RS09425	COG0085	RNA polymerase activity
AZI11_RS09435	COG0542	response to heat
AZI11_RS09440	COG4463	regulation of RNA biosynthetic process
AZI11_RS09490	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AZI11_RS09495	COG1428	Deoxynucleoside kinase
AZI11_RS09500	COG0833	amino acid
AZI11_RS09550	COG2814	Major facilitator Superfamily
AZI11_RS09565	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AZI11_RS09590	COG0456	acetyltransferase
AZI11_RS09610	COG0564	pseudouridine synthase activity
AZI11_RS09625	COG0110	maltose O-acetyltransferase activity
AZI11_RS09630	COG2160	L-arabinose isomerase activity
AZI11_RS09655	COG0110	maltose O-acetyltransferase activity
AZI11_RS09665	COG3940	Belongs to the glycosyl hydrolase 43 family
AZI11_RS09680	COG0514	ATP-dependent DNA helicase (RecQ)
AZI11_RS09695	COG4690	dipeptidase activity
AZI11_RS09705	COG0308	aminopeptidase N
AZI11_RS09770	COG0519	Catalyzes the synthesis of GMP from XMP
AZI11_RS09770	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AZI11_RS09780	COG1072	(Pantothenic acid kinase))
AZI11_RS09785	COG3973	AAA domain
AZI11_RS09790	COG0475	glutathione-regulated potassium exporter activity
AZI11_RS09790	COG0569	domain protein
AZI11_RS09800	COG4608	Belongs to the ABC transporter superfamily
AZI11_RS09805	COG0444	Belongs to the ABC transporter superfamily
AZI11_RS09810	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AZI11_RS09815	COG0601	transmembrane transport
AZI11_RS09820	COG4166	transmembrane transport
AZI11_RS09825	COG4166	transmembrane transport
AZI11_RS09830	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AZI11_RS09835	COG0765	amino acid transport
AZI11_RS09840	COG0765	amino acid transport
AZI11_RS09845	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZI11_RS09850	COG1126	abc transporter atp-binding protein
AZI11_RS09865	COG0735	belongs to the Fur family
AZI11_RS09870	COG0194	GDP metabolic process
AZI11_RS09880	COG0531	amino acid
AZI11_RS09885	COG2936	dipeptidyl-peptidase activity
AZI11_RS09890	COG2267	carboxylic ester hydrolase activity
AZI11_RS09895	COG1376	ErfK ybiS ycfS ynhG family protein
AZI11_RS09900	COG0488	(ABC) transporter
AZI11_RS09915	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AZI11_RS09920	COG4120	Belongs to the binding-protein-dependent transport system permease family
AZI11_RS09930	COG1307	EDD domain protein, DegV family
AZI11_RS09940	COG4120	Belongs to the binding-protein-dependent transport system permease family
AZI11_RS09980	COG2084	Dehydrogenase
AZI11_RS09985	COG0861	Integral membrane protein TerC family
AZI11_RS09995	COG1705	Flagellar rod assembly protein muramidase FlgJ
AZI11_RS10010	COG1028	Short-chain dehydrogenase reductase Sdr
AZI11_RS10025	COG2814	Major facilitator Superfamily
AZI11_RS10035	COG0789	Transcriptional regulator
AZI11_RS10040	COG3103	Sh3 type 3 domain protein
AZI11_RS10040	COG0791	NLP P60 protein
AZI11_RS10040	COG1388	LysM domain
AZI11_RS10050	COG0588	phosphoglycerate mutase activity
AZI11_RS10055	COG1368	sulfuric ester hydrolase activity
AZI11_RS10060	COG0492	ferredoxin-NADP+ reductase activity
AZI11_RS10090	COG0561	phosphatase activity
AZI11_RS10100	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AZI11_RS10105	COG0561	phosphatase activity
AZI11_RS10125	COG1686	Belongs to the peptidase S11 family
AZI11_RS10130	COG1686	Belongs to the peptidase S11 family
AZI11_RS10140	COG4172	Belongs to the ABC transporter superfamily
AZI11_RS10150	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AZI11_RS10185	COG2233	PERMEase
AZI11_RS10190	COG4152	abc transporter atp-binding protein
AZI11_RS10195	COG1668	transmembrane transport
AZI11_RS10215	COG0656	L-ascorbic acid biosynthetic process
AZI11_RS10230	COG0076	glutamate decarboxylase activity
AZI11_RS10235	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AZI11_RS10240	COG3875	lactate racemase activity
AZI11_RS10245	COG1691	(AIR) carboxylase
AZI11_RS10250	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
AZI11_RS10255	COG1606	tRNA processing
AZI11_RS10260	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AZI11_RS10265	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
AZI11_RS10295	COG3842	ATPase activity
AZI11_RS10300	COG1176	ABC-type spermidine putrescine transport system, permease component I
AZI11_RS10315	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AZI11_RS10320	COG0581	inorganic phosphate transmembrane transporter activity
AZI11_RS10325	COG0573	inorganic phosphate transmembrane transporter activity
AZI11_RS10365	COG2706	6-phosphogluconolactonase activity
AZI11_RS10375	COG0531	amino acid
AZI11_RS10390	COG0735	belongs to the Fur family
AZI11_RS10415	COG0589	response to stress
AZI11_RS10430	COG1846	Transcriptional regulator
AZI11_RS10435	COG3590	peptidase
AZI11_RS10445	COG2096	Adenosyltransferase
AZI11_RS10455	COG1131	(ABC) transporter
AZI11_RS10465	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AZI11_RS10475	COG1609	Transcriptional regulator
AZI11_RS10480	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
AZI11_RS10485	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AZI11_RS10490	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AZI11_RS10495	COG2190	(PTS) system
AZI11_RS10495	COG2211	Major facilitator Superfamily
AZI11_RS10505	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AZI11_RS10510	COG2017	converts alpha-aldose to the beta-anomer
AZI11_RS10515	COG1960	acyl-CoA dehydrogenase activity
AZI11_RS10525	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AZI11_RS10530	COG0604	alcohol dehydrogenase
AZI11_RS10535	COG0640	Transcriptional regulator
AZI11_RS10560	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AZI11_RS10565	COG1028	Short-chain dehydrogenase reductase Sdr
AZI11_RS10575	COG2814	Major facilitator Superfamily
AZI11_RS10580	COG0024	Methionine aminopeptidase
AZI11_RS10585	COG2226	methyltransferase
AZI11_RS10595	COG2094	Belongs to the DNA glycosylase MPG family
AZI11_RS10600	COG3189	MarR family transcriptional regulator
AZI11_RS10605	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AZI11_RS10620	COG0110	maltose O-acetyltransferase activity
AZI11_RS10630	COG0328	RNA-DNA hybrid ribonuclease activity
AZI11_RS10640	COG0402	S-adenosylhomocysteine deaminase activity
AZI11_RS10650	COG0351	phosphomethylpyrimidine kinase
AZI11_RS10660	COG2249	NAD(P)H dehydrogenase (quinone) activity
AZI11_RS10680	COG1278	Cold shock
AZI11_RS10685	COG0400	carboxylic ester hydrolase activity
AZI11_RS10700	COG4166	transmembrane transport
AZI11_RS10720	COG0509	glycine decarboxylation via glycine cleavage system
AZI11_RS10725	COG0667	Aldo Keto reductase
AZI11_RS10740	COG2011	ABC-type metal ion transport system permease component
AZI11_RS10745	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AZI11_RS10750	COG1464	Belongs to the NlpA lipoprotein family
AZI11_RS10755	COG0519	Catalyzes the synthesis of GMP from XMP
AZI11_RS10760	COG4166	transmembrane transport
AZI11_RS10770	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
AZI11_RS10775	COG0419	ATPase involved in DNA repair
AZI11_RS10780	COG0420	3'-5' exonuclease activity
AZI11_RS10785	COG2818	Glycosylase
AZI11_RS10805	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AZI11_RS10815	COG0789	Transcriptional regulator
AZI11_RS10820	COG1309	transcriptional regulator
AZI11_RS10840	COG2814	Major facilitator Superfamily
AZI11_RS10845	COG2814	Major facilitator Superfamily
AZI11_RS10850	COG1902	pentaerythritol trinitrate reductase activity
AZI11_RS10855	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
AZI11_RS10895	COG0163	prenyltransferase activity
AZI11_RS10900	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AZI11_RS10905	COG0583	DNA-binding transcription factor activity
AZI11_RS10910	COG0242	peptide deformylase activity
AZI11_RS10925	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AZI11_RS10930	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
AZI11_RS10935	COG1132	(ABC) transporter
AZI11_RS10940	COG1846	Transcriptional regulator
AZI11_RS10960	COG1131	(ABC) transporter
AZI11_RS10965	COG1725	Transcriptional regulator
AZI11_RS10975	COG0386	Belongs to the glutathione peroxidase family
AZI11_RS10985	COG2814	Major facilitator Superfamily
AZI11_RS10990	COG0561	phosphatase activity
AZI11_RS11005	COG4221	oxidoreductase activity
AZI11_RS11010	COG1733	regulation of RNA biosynthetic process
AZI11_RS11015	COG1302	Protein conserved in bacteria
AZI11_RS11020	COG1302	Protein conserved in bacteria
AZI11_RS11035	COG2261	transglycosylase associated protein
AZI11_RS11050	COG0477	Major facilitator Superfamily
AZI11_RS11090	COG0025	NhaP-type Na H and K H
AZI11_RS11105	COG2814	Major facilitator Superfamily
AZI11_RS11215	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AZI11_RS11215	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AZI11_RS11255	COG1611	Belongs to the LOG family
AZI11_RS11260	COG0588	phosphoglycerate mutase activity
AZI11_RS11270	COG0628	permease
AZI11_RS11275	COG1940	carbohydrate kinase activity
AZI11_RS11275	COG1846	Transcriptional regulator
AZI11_RS11285	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AZI11_RS11315	COG1511	domain protein
AZI11_RS11320	COG1686	Belongs to the peptidase S11 family
AZI11_RS11335	COG0517	IMP dehydrogenase activity
AZI11_RS11335	COG0516	GMP reductase activity
AZI11_RS11350	COG0012	GTP binding
AZI11_RS11355	COG4481	Protein conserved in bacteria
AZI11_RS11360	COG1475	DNA binding
AZI11_RS11365	COG1192	Involved in chromosome partitioning
AZI11_RS11375	COG0357	Ribosomal RNA small subunit methyltransferase G
AZI11_RS11395	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AZI11_RS11405	COG0702	epimerase
AZI11_RS11460	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AZI11_RS11500	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AZI11_RS11505	COG0577	efflux transmembrane transporter activity
AZI11_RS11505	COG1136	(ABC) transporter
AZI11_RS11510	COG0352	thiamine-phosphate diphosphorylase activity
AZI11_RS11515	COG0351	phosphomethylpyrimidine kinase
AZI11_RS11520	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
AZI11_RS11525	COG0300	oxidoreductase activity
AZI11_RS11530	COG0390	transport system, permease component
AZI11_RS11535	COG4619	ABC transporter
AZI11_RS11540	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AZI11_RS11580	COG0789	Transcriptional regulator
AZI11_RS11610	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AZI11_RS11615	COG1418	mRNA catabolic process
AZI11_RS11635	COG1396	sequence-specific DNA binding
AZI11_RS11650	COG1114	Component of the transport system for branched-chain amino acids
AZI11_RS11660	COG0531	amino acid
AZI11_RS11695	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AZI11_RS11720	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
AZI11_RS11730	COG2244	polysaccharide biosynthetic process
AZI11_RS11740	COG0823	Involved in the tonB-independent uptake of proteins
AZI11_RS11740	COG1506	peptidase
AZI11_RS11740	COG4946	Tricorn protease homolog
AZI11_RS11745	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AZI11_RS11755	COG1393	Belongs to the ArsC family
AZI11_RS11760	COG0025	NhaP-type Na H and K H
AZI11_RS11765	COG0737	Belongs to the 5'-nucleotidase family
AZI11_RS11790	COG1609	Transcriptional regulator
AZI11_RS11800	COG4475	Protein of unknown function (DUF436)
AZI11_RS11810	COG0351	phosphomethylpyrimidine kinase
AZI11_RS11815	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AZI11_RS11820	COG1316	TRANSCRIPTIONal
AZI11_RS11835	COG0772	Belongs to the SEDS family
AZI11_RS11840	COG2814	Major facilitator Superfamily
AZI11_RS11845	COG1733	regulation of RNA biosynthetic process
AZI11_RS11870	COG1940	carbohydrate kinase activity
AZI11_RS11885	COG2076	Multidrug Resistance protein
AZI11_RS11890	COG2076	Multidrug Resistance protein
AZI11_RS11925	COG4166	transmembrane transport
AZI11_RS11940	COG1609	Transcriptional regulator
AZI11_RS11950	COG0366	Alpha amylase catalytic
AZI11_RS11990	COG1902	pentaerythritol trinitrate reductase activity
AZI11_RS12000	COG1733	regulation of RNA biosynthetic process
AZI11_RS12015	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AZI11_RS12045	COG1881	PFAM PEBP family protein
AZI11_RS12060	COG0577	efflux transmembrane transporter activity
AZI11_RS12070	COG2814	Major facilitator Superfamily
AZI11_RS12095	COG3623	hexulose-6-phosphate isomerase
AZI11_RS12100	COG1070	Carbohydrate kinase
AZI11_RS12115	COG1609	Transcriptional regulator
AZI11_RS12130	COG0281	malic enzyme
AZI11_RS12135	COG0583	DNA-binding transcription factor activity
AZI11_RS12155	COG2957	Belongs to the agmatine deiminase family
AZI11_RS12160	COG0531	amino acid
AZI11_RS12165	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AZI11_RS12170	COG0531	amino acid
AZI11_RS12185	COG0183	Belongs to the thiolase family
AZI11_RS12215	COG2261	transglycosylase associated protein
AZI11_RS12225	COG2207	Transcriptional regulator
AZI11_RS12255	COG3022	response to hydroperoxide
AZI11_RS12260	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AZI11_RS12265	COG0284	orotidine-5'-phosphate decarboxylase activity
AZI11_RS12270	COG2814	Major facilitator Superfamily
AZI11_RS12280	COG2267	carboxylic ester hydrolase activity
AZI11_RS12285	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AZI11_RS12295	COG1397	ADP-ribosylglycohydrolase
AZI11_RS12300	COG2188	Transcriptional regulator
AZI11_RS12330	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AZI11_RS12350	COG4977	sequence-specific DNA binding
AZI11_RS12350	COG1917	Cupin 2, conserved barrel domain protein
AZI11_RS12365	COG0110	maltose O-acetyltransferase activity
AZI11_RS12400	COG4932	domain protein
AZI11_RS12400	COG4886	Leucine-rich repeat (LRR) protein
AZI11_RS12410	COG4886	Leucine-rich repeat (LRR) protein
AZI11_RS12410	COG4932	domain protein
AZI11_RS12425	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AZI11_RS12430	COG2814	Major facilitator Superfamily
AZI11_RS12435	COG2814	Major facilitator Superfamily
AZI11_RS12505	COG3250	beta-galactosidase activity
AZI11_RS12510	COG1959	2 iron, 2 sulfur cluster binding
AZI11_RS12515	COG0702	epimerase
AZI11_RS12535	COG1917	Cupin 2, conserved barrel domain protein
AZI11_RS12535	COG4977	sequence-specific DNA binding
AZI11_RS12550	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
AZI11_RS12555	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AZI11_RS12560	COG0726	polysaccharide deacetylase
AZI11_RS12575	COG0667	Aldo Keto reductase
AZI11_RS12580	COG2252	PERMEase
AZI11_RS12585	COG1846	Transcriptional regulator
AZI11_RS12605	COG4485	Bacterial membrane protein, YfhO
AZI11_RS12630	COG2211	Major facilitator Superfamily
AZI11_RS12635	COG2207	Transcriptional regulator
AZI11_RS12695	COG2814	Major facilitator Superfamily
AZI11_RS12705	COG1607	acyl-coa hydrolase
AZI11_RS12710	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AZI11_RS12720	COG1114	Component of the transport system for branched-chain amino acids
AZI11_RS12730	COG1011	Hydrolase
AZI11_RS12745	COG0445	tRNA wobble uridine modification
AZI11_RS12750	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AZI11_RS12760	COG0706	membrane insertase activity
AZI11_RS12765	COG0594	ribonuclease P activity
AZI11_RS12770	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AZI11_RS12830	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AZI11_RS12860	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AZI11_RS12860	COG1754	DNA topoisomerase type I activity
AZI11_RS12870	COG0542	response to heat
AZI11_RS12955	COG2826	transposase and inactivated derivatives, IS30 family
AZI11_RS12985	COG3328	transposase activity
AZI11_RS13065	COG2017	converts alpha-aldose to the beta-anomer
AZI11_RS13070	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AZI11_RS13150	COG0803	Belongs to the bacterial solute-binding protein 9 family
AZI11_RS13180	COG2826	transposase and inactivated derivatives, IS30 family
AZI11_RS13205	COG0210	DNA helicase
AZI11_RS13295	COG1192	Involved in chromosome partitioning
AZI11_RS13445	COG1442	glycosyl transferase family 8
AZI11_RS13455	COG1132	(ABC) transporter
AZI11_RS13460	COG1442	glycosyl transferase family 8
AZI11_RS13465	COG0402	S-adenosylhomocysteine deaminase activity
AZI11_RS13480	COG1192	Involved in chromosome partitioning
AZI11_RS13560	COG0542	response to heat
AZI11_RS13665	COG0076	glutamate decarboxylase activity
AZI11_RS13700	COG0531	amino acid
AZI11_RS13720	COG1192	Involved in chromosome partitioning
AZI11_RS13730	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AZI11_RS13825	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
AZI11_RS13835	COG0463	Glycosyl transferase, family 2
AZI11_RS13895	COG1192	Involved in chromosome partitioning
AZI11_RS13905	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AZI11_RS14000	COG1192	Involved in chromosome partitioning
AZI11_RS14115	COG0589	response to stress
AZI11_RS14135	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AZI11_RS14140	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AZI11_RS14145	COG0148	phosphopyruvate hydratase activity
AZI11_RS14195	COG0629	single-stranded DNA binding
AZI11_RS14195	COG0629	single-stranded DNA binding
AZI11_RS14245	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AZI11_RS14305	COG1192	Involved in chromosome partitioning
AZI11_RS14380	COG3953	SLT domain
AZI11_RS14380	COG5280	Phage tail tape measure protein TP901
AZI11_RS14905	COG2801	Transposase and inactivated derivatives
AZI11_RS14945	COG0791	NLP P60 protein
AZI11_RS14945	COG3883	PFAM NLP P60 protein