locus-tag	class	description
IGB11_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IGB11_RS00010	COG0592	DNA-directed DNA polymerase activity
IGB11_RS00020	COG2501	S4 domain
IGB11_RS00030	COG0187	DNA topoisomerase II activity
IGB11_RS00040	COG0360	Binds together with S18 to 16S ribosomal RNA
IGB11_RS00045	COG0629	single-stranded DNA binding
IGB11_RS00060	COG2801	Transposase and inactivated derivatives
IGB11_RS00075	COG2084	Dehydrogenase
IGB11_RS00080	COG1215	transferase activity, transferring glycosyl groups
IGB11_RS00090	COG0367	asparagine synthase
IGB11_RS00105	COG0028	Belongs to the TPP enzyme family
IGB11_RS00140	COG4975	Glucose uptake
IGB11_RS00155	COG0697	spore germination
IGB11_RS00165	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IGB11_RS00170	COG0626	cystathionine gamma-synthase activity
IGB11_RS00175	COG0371	Dehydrogenase
IGB11_RS00205	COG1132	(ABC) transporter
IGB11_RS00210	COG1132	(ABC) transporter
IGB11_RS00225	COG1696	Membrane protein involved in D-alanine export
IGB11_RS00240	COG2274	protein secretion by the type I secretion system
IGB11_RS00250	COG0745	RESPONSE REGULATOR receiver
IGB11_RS00255	COG5002	protein histidine kinase activity
IGB11_RS00265	COG4853	Protein conserved in bacteria
IGB11_RS00275	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
IGB11_RS00280	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IGB11_RS00295	COG2271	Major facilitator Superfamily
IGB11_RS00355	COG1442	glycosyl transferase family 8
IGB11_RS00355	COG1216	Glycosyl transferase, family 2
IGB11_RS00360	COG1216	Glycosyl transferase, family 2
IGB11_RS00360	COG1442	glycosyl transferase family 8
IGB11_RS00365	COG1216	Glycosyl transferase, family 2
IGB11_RS00365	COG1442	glycosyl transferase family 8
IGB11_RS00370	COG1215	transferase activity, transferring glycosyl groups
IGB11_RS00380	COG0438	transferase activity, transferring glycosyl groups
IGB11_RS00405	COG4372	Transposase
IGB11_RS00415	COG0438	transferase activity, transferring glycosyl groups
IGB11_RS00425	COG1442	glycosyl transferase family 8
IGB11_RS00425	COG1216	Glycosyl transferase, family 2
IGB11_RS00435	COG1216	Glycosyl transferase, family 2
IGB11_RS00435	COG1442	glycosyl transferase family 8
IGB11_RS00450	COG1442	glycosyl transferase family 8
IGB11_RS00455	COG0534	Mate efflux family protein
IGB11_RS00465	COG0488	(ABC) transporter
IGB11_RS00475	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
IGB11_RS00510	COG0765	amino acid transport
IGB11_RS00515	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IGB11_RS00545	COG1263	PTS System
IGB11_RS00545	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IGB11_RS00545	COG2190	(PTS) system
IGB11_RS00550	COG0366	Alpha amylase catalytic
IGB11_RS00555	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IGB11_RS00560	COG0569	domain protein
IGB11_RS00570	COG1216	Glycosyl transferase, family 2
IGB11_RS00585	COG1268	BioY protein
IGB11_RS00590	COG0477	Major facilitator Superfamily
IGB11_RS00595	COG1686	Belongs to the peptidase S11 family
IGB11_RS00615	COG2814	Major facilitator Superfamily
IGB11_RS00620	COG0789	Transcriptional regulator
IGB11_RS00625	COG0346	lactoylglutathione lyase activity
IGB11_RS00630	COG1811	Na channel or pump
IGB11_RS00640	COG2197	response regulator
IGB11_RS00645	COG4585	Histidine kinase
IGB11_RS00660	COG3715	PTS system
IGB11_RS00665	COG3716	PTS system mannose fructose sorbose family IID component
IGB11_RS00685	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IGB11_RS00690	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IGB11_RS00695	COG1573	uracil-dna glycosylase
IGB11_RS00705	COG1695	Transcriptional regulator
IGB11_RS00735	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IGB11_RS00740	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
IGB11_RS00750	COG1176	ABC-type spermidine putrescine transport system, permease component I
IGB11_RS00755	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
IGB11_RS00780	COG1376	ErfK ybiS ycfS ynhG family protein
IGB11_RS00785	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IGB11_RS00800	COG0588	phosphoglycerate mutase activity
IGB11_RS00820	COG2217	Heavy metal translocating P-type atpase
IGB11_RS00845	COG0745	RESPONSE REGULATOR receiver
IGB11_RS00855	COG5002	protein histidine kinase activity
IGB11_RS00860	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IGB11_RS00895	COG1125	glycine betaine transport
IGB11_RS00940	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IGB11_RS00945	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IGB11_RS00950	COG1464	Belongs to the NlpA lipoprotein family
IGB11_RS00960	COG2011	ABC-type metal ion transport system permease component
IGB11_RS00970	COG0778	Nitroreductase
IGB11_RS00985	COG0446	pyridine nucleotide-disulphide oxidoreductase
IGB11_RS00990	COG1982	Orn Lys Arg decarboxylase major
IGB11_RS01000	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
IGB11_RS01005	COG0732	type I restriction modification DNA specificity domain
IGB11_RS01015	COG4974	Belongs to the 'phage' integrase family
IGB11_RS01035	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IGB11_RS01040	COG2011	ABC-type metal ion transport system permease component
IGB11_RS01045	COG1464	Belongs to the NlpA lipoprotein family
IGB11_RS01085	COG0095	Lipoate-protein ligase
IGB11_RS01105	COG3830	Belongs to the UPF0237 family
IGB11_RS01115	COG1349	DNA-binding transcription factor activity
IGB11_RS01120	COG1105	Belongs to the carbohydrate kinase PfkB family
IGB11_RS01125	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IGB11_RS01125	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IGB11_RS01125	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IGB11_RS01140	COG0531	amino acid
IGB11_RS01145	COG2217	Heavy metal translocating P-type atpase
IGB11_RS01150	COG1307	EDD domain protein, DegV family
IGB11_RS01155	COG0463	Glycosyl transferase, family 2
IGB11_RS01160	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IGB11_RS01160	COG0519	Catalyzes the synthesis of GMP from XMP
IGB11_RS01165	COG2050	protein possibly involved in aromatic compounds catabolism
IGB11_RS01170	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IGB11_RS01185	COG2814	Major facilitator Superfamily
IGB11_RS01210	COG0730	response to heat
IGB11_RS01215	COG0583	DNA-binding transcription factor activity
IGB11_RS01230	COG0028	Belongs to the TPP enzyme family
IGB11_RS01235	COG3527	Alpha-acetolactate decarboxylase
IGB11_RS01240	COG0833	amino acid
IGB11_RS01325	COG0505	Belongs to the CarA family
IGB11_RS01335	COG0167	dihydroorotate dehydrogenase activity
IGB11_RS01345	COG4463	regulation of RNA biosynthetic process
IGB11_RS01350	COG0542	response to heat
IGB11_RS01370	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
IGB11_RS01395	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IGB11_RS01420	COG2271	Major facilitator Superfamily
IGB11_RS01425	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IGB11_RS01430	COG0577	efflux transmembrane transporter activity
IGB11_RS01430	COG1136	(ABC) transporter
IGB11_RS01435	COG1309	transcriptional regulator
IGB11_RS01445	COG1132	(ABC) transporter
IGB11_RS01455	COG2153	protein acetylation
IGB11_RS01460	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
IGB11_RS01465	COG1704	LemA family
IGB11_RS01480	COG3973	AAA domain
IGB11_RS01500	COG1131	(ABC) transporter
IGB11_RS01510	COG1309	transcriptional regulator
IGB11_RS01530	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IGB11_RS01530	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IGB11_RS01540	COG0084	hydrolase, TatD family'
IGB11_RS01555	COG4466	Protein conserved in bacteria
IGB11_RS01565	COG0436	Aminotransferase
IGB11_RS01570	COG1438	arginine binding
IGB11_RS01580	COG0004	ammonium transporteR
IGB11_RS01595	COG0436	Aminotransferase
IGB11_RS01600	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IGB11_RS01620	COG0789	Transcriptional regulator
IGB11_RS01625	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IGB11_RS01640	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IGB11_RS01670	COG0813	purine-nucleoside phosphorylase activity
IGB11_RS01675	COG0488	(ABC) transporter
IGB11_RS01705	COG0464	growth
IGB11_RS01735	COG0561	phosphatase activity
IGB11_RS01740	COG1078	dGTPase activity
IGB11_RS01775	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IGB11_RS01780	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IGB11_RS01815	COG2252	PERMEase
IGB11_RS01825	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IGB11_RS01850	COG2337	Toxic component of a toxin-antitoxin (TA) module
IGB11_RS01860	COG1801	Protein of unknown function DUF72
IGB11_RS01870	COG0242	peptide deformylase activity
IGB11_RS01885	COG1597	lipid kinase activity
IGB11_RS01900	COG2137	regulation of response to DNA damage stimulus
IGB11_RS01905	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IGB11_RS01915	COG0628	permease
IGB11_RS01925	COG1134	teichoic acid transport
IGB11_RS01935	COG3250	beta-galactosidase activity
IGB11_RS01950	COG1609	Transcriptional regulator
IGB11_RS01960	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IGB11_RS01990	COG0542	response to heat
IGB11_RS02000	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IGB11_RS02005	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IGB11_RS02015	COG0438	transferase activity, transferring glycosyl groups
IGB11_RS02020	COG0438	transferase activity, transferring glycosyl groups
IGB11_RS02035	COG1368	sulfuric ester hydrolase activity
IGB11_RS02125	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
IGB11_RS02130	COG4862	establishment of competence for transformation
IGB11_RS02140	COG1164	Oligoendopeptidase f
IGB11_RS02155	COG0573	inorganic phosphate transmembrane transporter activity
IGB11_RS02160	COG0581	inorganic phosphate transmembrane transporter activity
IGB11_RS02175	COG0704	Plays a role in the regulation of phosphate uptake
IGB11_RS02200	COG1272	protein, Hemolysin III
IGB11_RS02205	COG0640	Transcriptional regulator
IGB11_RS02210	COG0328	RNA-DNA hybrid ribonuclease activity
IGB11_RS02230	COG0006	proline dipeptidase activity
IGB11_RS02235	COG1609	Transcriptional regulator
IGB11_RS02255	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IGB11_RS02315	COG3561	AntA/AntB antirepressor
IGB11_RS02355	COG0305	Participates in initiation and elongation during chromosome replication
IGB11_RS02505	COG0740	serine-type endopeptidase activity
IGB11_RS02640	COG0827	DNA restriction-modification system
IGB11_RS02645	COG1113	amino acid transport
IGB11_RS02655	COG4470	Protein conserved in bacteria
IGB11_RS02660	COG0647	UMP catabolic process
IGB11_RS02670	COG0586	Pfam SNARE associated Golgi protein
IGB11_RS02680	COG1098	S1 RNA binding domain
IGB11_RS02805	COG1113	amino acid transport
IGB11_RS02815	COG2244	polysaccharide biosynthetic process
IGB11_RS02820	COG1187	pseudouridine synthase activity
IGB11_RS02825	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IGB11_RS02850	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IGB11_RS02860	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IGB11_RS02865	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IGB11_RS02875	COG1028	Short-chain dehydrogenase reductase Sdr
IGB11_RS02880	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IGB11_RS02885	COG0511	ligase activity, forming carbon-carbon bonds
IGB11_RS02895	COG0439	Biotin carboxylase
IGB11_RS02905	COG0825	malonyl-CoA metabolic process
IGB11_RS02910	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
IGB11_RS02915	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IGB11_RS02930	COG1368	sulfuric ester hydrolase activity
IGB11_RS02935	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
IGB11_RS02955	COG0668	transmembrane transport
IGB11_RS02965	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IGB11_RS02995	COG0537	adenosine 5'-monophosphoramidase activity
IGB11_RS03000	COG1131	(ABC) transporter
IGB11_RS03005	COG4473	ABC transporter
IGB11_RS03010	COG0510	thiamine kinase activity
IGB11_RS03025	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IGB11_RS03030	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IGB11_RS03035	COG1674	ftsk spoiiie
IGB11_RS03050	COG0670	Belongs to the BI1 family
IGB11_RS03070	COG0237	dephospho-CoA kinase activity
IGB11_RS03085	COG1484	DNA-dependent DNA replication
IGB11_RS03095	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IGB11_RS03110	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
IGB11_RS03115	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IGB11_RS03120	COG1534	Rna-binding protein
IGB11_RS03125	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IGB11_RS03130	COG1713	HD superfamily hydrolase involved in NAD metabolism
IGB11_RS03135	COG0799	negative regulation of ribosome biogenesis
IGB11_RS03140	COG2226	methyltransferase
IGB11_RS03160	COG0204	Acyl-transferase
IGB11_RS03165	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
IGB11_RS03170	COG2827	Endonuclease containing a URI domain
IGB11_RS03185	COG0582	viral genome integration into host DNA
IGB11_RS03200	COG1396	sequence-specific DNA binding
IGB11_RS03430	COG1428	Deoxynucleoside kinase
IGB11_RS03435	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IGB11_RS03440	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IGB11_RS03445	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IGB11_RS03460	COG0745	RESPONSE REGULATOR receiver
IGB11_RS03465	COG5002	protein histidine kinase activity
IGB11_RS03475	COG0706	membrane insertase activity
IGB11_RS03485	COG3425	synthase
IGB11_RS03505	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IGB11_RS03510	COG1302	Protein conserved in bacteria
IGB11_RS03530	COG1722	exodeoxyribonuclease VII activity
IGB11_RS03535	COG0142	geranyltranstransferase activity
IGB11_RS03540	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
IGB11_RS03545	COG1438	arginine binding
IGB11_RS03550	COG0497	DNA recombination
IGB11_RS03560	COG4224	UPF0291 protein
IGB11_RS03595	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IGB11_RS03600	COG0457	Tetratricopeptide repeat
IGB11_RS03600	COG0705	Rhomboid family
IGB11_RS03610	COG1940	carbohydrate kinase activity
IGB11_RS03615	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IGB11_RS03630	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
IGB11_RS03635	COG0789	Transcriptional regulator
IGB11_RS03640	COG0174	glutamine synthetase
IGB11_RS03650	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IGB11_RS03670	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IGB11_RS03675	COG4589	Belongs to the CDS family
IGB11_RS03680	COG0750	zinc metalloprotease
IGB11_RS03700	COG0195	Participates in both transcription termination and antitermination
IGB11_RS03705	COG2740	Nucleic-acid-binding protein implicated in transcription termination
IGB11_RS03730	COG0196	riboflavin kinase activity
IGB11_RS03740	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IGB11_RS03750	COG0484	heat shock protein binding
IGB11_RS03770	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IGB11_RS03775	COG1126	abc transporter atp-binding protein
IGB11_RS03790	COG3442	glutamine amidotransferase
IGB11_RS03795	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IGB11_RS03800	COG1435	thymidine kinase activity
IGB11_RS03810	COG2890	protein-(glutamine-N5) methyltransferase activity
IGB11_RS03815	COG0009	L-threonylcarbamoyladenylate synthase
IGB11_RS03825	COG0356	it plays a direct role in the translocation of protons across the membrane
IGB11_RS03830	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IGB11_RS03870	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IGB11_RS03875	COG1077	Cell shape determining protein MreB Mrl
IGB11_RS03890	COG0772	Belongs to the SEDS family
IGB11_RS03920	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IGB11_RS03925	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IGB11_RS03935	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IGB11_RS03935	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IGB11_RS03940	COG0631	protein serine/threonine phosphatase activity
IGB11_RS03945	COG0515	serine threonine protein kinase
IGB11_RS03945	COG2815	serine threonine protein kinase
IGB11_RS03950	COG1162	GTPase activity
IGB11_RS03970	COG1461	Dihydroxyacetone kinase
IGB11_RS03975	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IGB11_RS03985	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IGB11_RS03995	COG1196	nuclear chromosome segregation
IGB11_RS04000	COG0552	protein localization to endoplasmic reticulum
IGB11_RS04010	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IGB11_RS04020	COG1837	Belongs to the UPF0109 family
IGB11_RS04035	COG1247	-acetyltransferase
IGB11_RS04045	COG0531	amino acid
IGB11_RS04100	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IGB11_RS04110	COG5503	Protein of unknown function (DUF1447)
IGB11_RS04130	COG4476	Belongs to the UPF0223 family
IGB11_RS04135	COG0483	inositol monophosphate 1-phosphatase activity
IGB11_RS04140	COG1217	gtp-binding protein TYPA
IGB11_RS04150	COG3715	PTS system
IGB11_RS04155	COG3716	PTS system mannose fructose sorbose family IID component
IGB11_RS04160	COG0772	Belongs to the SEDS family
IGB11_RS04165	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
IGB11_RS04170	COG4471	UPF0298 protein
IGB11_RS04175	COG0742	ribosomal rna small subunit methyltransferase
IGB11_RS04180	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IGB11_RS04185	COG3480	Lon protease (S16) C-terminal proteolytic domain
IGB11_RS04195	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
IGB11_RS04200	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IGB11_RS04225	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IGB11_RS04235	COG0151	Belongs to the GarS family
IGB11_RS04260	COG2801	Transposase and inactivated derivatives
IGB11_RS04275	COG4974	Belongs to the 'phage' integrase family
IGB11_RS04280	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IGB11_RS04285	COG0583	DNA-binding transcription factor activity
IGB11_RS04300	COG1011	Hydrolase
IGB11_RS04310	COG1596	polysaccharide export
IGB11_RS04310	COG1555	photosystem II stabilization
IGB11_RS04315	COG2131	deaminase
IGB11_RS04320	COG0658	competence protein
IGB11_RS04320	COG2333	competence protein COMEC
IGB11_RS04325	COG1466	dna polymerase III delta subunit
IGB11_RS04330	COG1304	FMN binding
IGB11_RS04350	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IGB11_RS04350	COG1199	ATP-dependent helicase activity
IGB11_RS04360	COG0436	Aminotransferase
IGB11_RS04375	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IGB11_RS04390	COG0438	transferase activity, transferring glycosyl groups
IGB11_RS04400	COG1216	Glycosyl transferase, family 2
IGB11_RS04425	COG1610	YqeY-like protein
IGB11_RS04440	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IGB11_RS04455	COG0488	(ABC) transporter
IGB11_RS04470	COG0656	L-ascorbic acid biosynthetic process
IGB11_RS04475	COG0789	Transcriptional regulator
IGB11_RS04480	COG4989	oxidoreductase activity
IGB11_RS04485	COG2755	lipolytic protein G-D-S-L family
IGB11_RS04540	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
IGB11_RS04575	COG2801	Transposase and inactivated derivatives
IGB11_RS04580	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IGB11_RS04595	COG3775	system Galactitol-specific IIC component
IGB11_RS04610	COG0406	alpha-ribazole phosphatase activity
IGB11_RS04620	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IGB11_RS04645	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IGB11_RS04655	COG1733	regulation of RNA biosynthetic process
IGB11_RS04665	COG0072	phenylalanine-tRNA ligase activity
IGB11_RS04665	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IGB11_RS04670	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IGB11_RS04680	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IGB11_RS04700	COG2264	protein methyltransferase activity
IGB11_RS04705	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IGB11_RS04710	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IGB11_RS04730	COG0564	pseudouridine synthase activity
IGB11_RS04740	COG2233	PERMEase
IGB11_RS04745	COG0505	Belongs to the CarA family
IGB11_RS04770	COG1227	inorganic diphosphatase activity
IGB11_RS04780	COG0436	Aminotransferase
IGB11_RS04785	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IGB11_RS04805	COG0116	Belongs to the methyltransferase superfamily
IGB11_RS04810	COG0328	RNA-DNA hybrid ribonuclease activity
IGB11_RS04840	COG0477	Major facilitator Superfamily
IGB11_RS04845	COG2384	SAM-dependent methyltransferase
IGB11_RS04850	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IGB11_RS04865	COG0697	spore germination
IGB11_RS04870	COG0457	Tetratricopeptide repeat
IGB11_RS04890	COG1757	Na H antiporter
IGB11_RS04910	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IGB11_RS04915	COG1104	cysteine desulfurase activity
IGB11_RS04930	COG0542	response to heat
IGB11_RS04940	COG0587	DNA-directed DNA polymerase activity
IGB11_RS04965	COG3759	membrane
IGB11_RS04975	COG0187	DNA topoisomerase II activity
IGB11_RS04980	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IGB11_RS04990	COG1293	RNA-binding protein homologous to eukaryotic snRNP
IGB11_RS05275	COG2801	Transposase and inactivated derivatives
IGB11_RS05405	COG1307	EDD domain protein, DegV family
IGB11_RS05430	COG0697	spore germination
IGB11_RS05440	COG4152	abc transporter atp-binding protein
IGB11_RS05460	COG0539	negative regulation of cytoplasmic translation
IGB11_RS05470	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
IGB11_RS05475	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IGB11_RS05480	COG1696	Membrane protein involved in D-alanine export
IGB11_RS05485	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IGB11_RS05505	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
IGB11_RS05515	COG1702	phosphate starvation-inducible protein PhoH
IGB11_RS05520	COG4991	sh3 domain protein
IGB11_RS05520	COG3103	Sh3 type 3 domain protein
IGB11_RS05520	COG0860	N-Acetylmuramoyl-L-alanine amidase
IGB11_RS05535	COG0514	ATP-dependent DNA helicase (RecQ)
IGB11_RS05545	COG1914	H( )-stimulated, divalent metal cation uptake system
IGB11_RS05550	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IGB11_RS05555	COG0358	DNA primase activity
IGB11_RS05575	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IGB11_RS05605	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
IGB11_RS05615	COG1051	belongs to the nudix hydrolase family
IGB11_RS05630	COG0110	maltose O-acetyltransferase activity
IGB11_RS05660	COG1757	Na H antiporter
IGB11_RS05670	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IGB11_RS05680	COG2996	Protein conserved in bacteria
IGB11_RS05690	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IGB11_RS05695	COG1187	pseudouridine synthase activity
IGB11_RS05725	COG4974	Belongs to the 'phage' integrase family
IGB11_RS05730	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IGB11_RS05735	COG1597	lipid kinase activity
IGB11_RS05750	COG0534	Mate efflux family protein
IGB11_RS05790	COG0211	Belongs to the bacterial ribosomal protein bL27 family
IGB11_RS05795	COG2868	ribosomal protein
IGB11_RS05855	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IGB11_RS05900	COG0702	epimerase
IGB11_RS05920	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IGB11_RS05920	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
IGB11_RS05930	COG1073	alpha beta
IGB11_RS05935	COG0561	phosphatase activity
IGB11_RS05950	COG0019	diaminopimelate decarboxylase activity
IGB11_RS05955	COG1942	4-Oxalocrotonate Tautomerase
IGB11_RS05970	COG2207	Transcriptional regulator
IGB11_RS06005	COG1252	NADH dehydrogenase
IGB11_RS06015	COG0142	geranyltranstransferase activity
IGB11_RS06020	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IGB11_RS06025	COG4988	ABC transporter
IGB11_RS06030	COG1294	oxidase, subunit
IGB11_RS06035	COG1271	oxidase subunit
IGB11_RS06105	COG3599	regulation of cell shape
IGB11_RS06110	COG2302	S4 RNA-binding domain
IGB11_RS06125	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IGB11_RS06155	COG0768	penicillin binding
IGB11_RS06180	COG0527	aspartate kinase activity
IGB11_RS06195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IGB11_RS06200	COG1126	abc transporter atp-binding protein
IGB11_RS06205	COG0765	amino acid transport
IGB11_RS06210	COG2894	cell division
IGB11_RS06225	COG1792	Involved in formation and maintenance of cell shape
IGB11_RS06230	COG1077	Cell shape determining protein MreB Mrl
IGB11_RS06245	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IGB11_RS06280	COG0285	dihydrofolate synthase activity
IGB11_RS06295	COG0525	valine-tRNA ligase activity
IGB11_RS06305	COG1104	cysteine desulfurase activity
IGB11_RS06310	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
IGB11_RS06315	COG1956	GAF domain-containing protein
IGB11_RS06330	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IGB11_RS06345	COG0589	response to stress
IGB11_RS06350	COG0519	Catalyzes the synthesis of GMP from XMP
IGB11_RS06380	COG0768	penicillin binding
IGB11_RS06395	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
IGB11_RS06395	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
IGB11_RS06400	COG0300	oxidoreductase activity
IGB11_RS06420	COG2755	lipolytic protein G-D-S-L family
IGB11_RS06420	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
IGB11_RS06435	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IGB11_RS06455	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IGB11_RS06460	COG1719	4-vinyl reductase, 4VR
IGB11_RS06465	COG3118	belongs to the thioredoxin family
IGB11_RS06505	COG0513	Belongs to the DEAD box helicase family
IGB11_RS06510	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
IGB11_RS06660	COG1475	DNA binding
IGB11_RS06710	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
IGB11_RS06770	COG3561	AntA/AntB antirepressor
IGB11_RS06810	COG0582	viral genome integration into host DNA
IGB11_RS06820	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IGB11_RS06830	COG1139	Iron-sulfur cluster binding protein
IGB11_RS06835	COG0247	lactate metabolic process
IGB11_RS06840	COG0531	amino acid
IGB11_RS06865	COG1862	Preprotein translocase
IGB11_RS06870	COG0343	queuine tRNA-ribosyltransferase activity
IGB11_RS06875	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IGB11_RS06905	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IGB11_RS06910	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IGB11_RS06915	COG1426	Protein conserved in bacteria
IGB11_RS06920	COG0300	oxidoreductase activity
IGB11_RS06925	COG0612	Peptidase, M16
IGB11_RS06930	COG0612	Peptidase, M16
IGB11_RS06935	COG1674	ftsk spoiiie
IGB11_RS06970	COG2706	6-phosphogluconolactonase activity
IGB11_RS06995	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IGB11_RS07010	COG2176	DNA-directed DNA polymerase activity
IGB11_RS07015	COG0802	atpase or kinase
IGB11_RS07020	COG0280	phosphate acetyltransferase
IGB11_RS07025	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IGB11_RS07030	COG0561	phosphatase activity
IGB11_RS07045	COG0557	exoribonuclease II activity
IGB11_RS07050	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IGB11_RS07060	COG2814	Major facilitator Superfamily
IGB11_RS07065	COG5002	protein histidine kinase activity
IGB11_RS07065	COG3850	Histidine kinase
IGB11_RS07070	COG0745	RESPONSE REGULATOR receiver
IGB11_RS07075	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IGB11_RS07120	COG0391	Required for morphogenesis under gluconeogenic growth conditions
IGB11_RS07150	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IGB11_RS07155	COG0556	nucleotide-excision repair
IGB11_RS07160	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IGB11_RS07175	COG1950	PFAM Membrane protein of
IGB11_RS07180	COG1983	PspC domain protein
IGB11_RS07185	COG5002	protein histidine kinase activity
IGB11_RS07190	COG0745	RESPONSE REGULATOR receiver
IGB11_RS07210	COG2807	transmembrane transport
IGB11_RS07225	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
IGB11_RS07230	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IGB11_RS07240	COG0531	amino acid
IGB11_RS07245	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
IGB11_RS07265	COG1266	CAAX protease self-immunity
IGB11_RS07275	COG0488	(ABC) transporter
IGB11_RS07290	COG1214	PFAM Peptidase M22, glycoprotease
IGB11_RS07315	COG0470	DNA polymerase III
IGB11_RS07340	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IGB11_RS07350	COG0590	tRNA wobble adenosine to inosine editing
IGB11_RS07355	COG2813	Specifically methylates the guanine in position
IGB11_RS07360	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IGB11_RS07365	COG1780	Probably involved in ribonucleotide reductase function
IGB11_RS07370	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IGB11_RS07375	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IGB11_RS07380	COG0392	lysyltransferase activity
IGB11_RS07380	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IGB11_RS07410	COG0250	Participates in transcription elongation, termination and antitermination
IGB11_RS07430	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IGB11_RS07435	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IGB11_RS07450	COG4956	integral membrane protein (PIN domain superfamily)
IGB11_RS07460	COG0756	dUTP diphosphatase activity
IGB11_RS07480	COG0588	phosphoglycerate mutase activity
IGB11_RS07490	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IGB11_RS07500	COG3091	SprT-like family
IGB11_RS07505	COG2183	response to ionizing radiation
IGB11_RS07515	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IGB11_RS07525	COG2188	Transcriptional regulator
IGB11_RS07530	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IGB11_RS07545	COG3104	oligopeptide transport
IGB11_RS07580	COG0791	NLP P60 protein
IGB11_RS07580	COG1388	LysM domain
IGB11_RS07585	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IGB11_RS07590	COG0024	Methionine aminopeptidase
IGB11_RS07595	COG0716	FMN binding
IGB11_RS07600	COG2246	polysaccharide biosynthetic process
IGB11_RS07640	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
IGB11_RS07645	COG2309	aminopeptidase activity
IGB11_RS07655	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IGB11_RS07665	COG2017	converts alpha-aldose to the beta-anomer
IGB11_RS07675	COG1609	Transcriptional regulator
IGB11_RS07700	COG0673	inositol 2-dehydrogenase activity
IGB11_RS07715	COG0058	SHG alpha-glucan phosphorylase activity
IGB11_RS07725	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IGB11_RS07740	COG0366	Alpha amylase catalytic
IGB11_RS07750	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IGB11_RS07755	COG1012	belongs to the aldehyde dehydrogenase family
IGB11_RS07770	COG2239	Acts as a magnesium transporter
IGB11_RS07775	COG0564	pseudouridine synthase activity
IGB11_RS07785	COG2357	RelA SpoT domain protein
IGB11_RS07800	COG2233	PERMEase
IGB11_RS07810	COG1705	Flagellar rod assembly protein muramidase FlgJ
IGB11_RS07825	COG0281	malic enzyme
IGB11_RS07830	COG0583	DNA-binding transcription factor activity
IGB11_RS07845	COG0589	response to stress
IGB11_RS07870	COG0586	Pfam SNARE associated Golgi protein
IGB11_RS07885	COG0471	metal ion transport
IGB11_RS07895	COG0114	fumarate hydratase activity
IGB11_RS07905	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IGB11_RS07910	COG1393	Belongs to the ArsC family
IGB11_RS07915	COG0602	queuosine metabolic process
IGB11_RS07920	COG1328	CTP reductase activity
IGB11_RS07925	COG4475	Protein of unknown function (DUF436)
IGB11_RS07940	COG2801	Transposase and inactivated derivatives
IGB11_RS07960	COG0464	growth
IGB11_RS08030	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IGB11_RS08040	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IGB11_RS08045	COG1597	lipid kinase activity
IGB11_RS08075	COG0210	DNA helicase
IGB11_RS08080	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IGB11_RS08130	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
IGB11_RS08135	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IGB11_RS08140	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IGB11_RS08150	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
IGB11_RS08155	COG0037	tRNA processing
IGB11_RS08160	COG1098	S1 RNA binding domain
IGB11_RS08170	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
IGB11_RS08175	COG2244	polysaccharide biosynthetic process
IGB11_RS08180	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IGB11_RS08210	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IGB11_RS08215	COG2801	Transposase and inactivated derivatives
IGB11_RS08230	COG0735	belongs to the Fur family
IGB11_RS08235	COG1988	membrane-bound metal-dependent
IGB11_RS08240	COG0419	ATPase involved in DNA repair
IGB11_RS08245	COG0420	3'-5' exonuclease activity
IGB11_RS08250	COG1388	LysM domain
IGB11_RS08250	COG0791	NLP P60 protein
IGB11_RS08255	COG0028	Belongs to the TPP enzyme family
IGB11_RS08280	COG0778	Nitroreductase
IGB11_RS08285	COG3973	AAA domain
IGB11_RS08290	COG0475	glutathione-regulated potassium exporter activity
IGB11_RS08290	COG0569	domain protein
IGB11_RS08475	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IGB11_RS08485	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IGB11_RS08500	COG0531	amino acid
IGB11_RS08505	COG0765	amino acid transport
IGB11_RS08510	COG0765	amino acid transport
IGB11_RS08515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IGB11_RS08520	COG1126	abc transporter atp-binding protein
IGB11_RS08540	COG0735	belongs to the Fur family
IGB11_RS08545	COG0531	amino acid
IGB11_RS08550	COG0516	GMP reductase activity
IGB11_RS08550	COG0517	IMP dehydrogenase activity
IGB11_RS08560	COG2365	Tyrosine phosphatase family
IGB11_RS08565	COG1253	flavin adenine dinucleotide binding
IGB11_RS08575	COG0564	pseudouridine synthase activity
IGB11_RS08585	COG1136	(ABC) transporter
IGB11_RS08620	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IGB11_RS08625	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IGB11_RS08630	COG1028	Short-chain dehydrogenase reductase Sdr
IGB11_RS08640	COG4708	membrane
IGB11_RS08645	COG1307	EDD domain protein, DegV family
IGB11_RS08665	COG0561	phosphatase activity
IGB11_RS08685	COG1278	Cold shock
IGB11_RS08695	COG0564	pseudouridine synthase activity
IGB11_RS08735	COG0708	Exodeoxyribonuclease III
IGB11_RS08740	COG1511	domain protein
IGB11_RS08740	COG1511	domain protein
IGB11_RS08765	COG0588	phosphoglycerate mutase activity
IGB11_RS08770	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
IGB11_RS08775	COG0628	permease
IGB11_RS08780	COG0697	spore germination
IGB11_RS08790	COG2017	converts alpha-aldose to the beta-anomer
IGB11_RS08810	COG1733	regulation of RNA biosynthetic process
IGB11_RS08815	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IGB11_RS08820	COG2188	Transcriptional regulator
IGB11_RS08825	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
IGB11_RS08830	COG1335	isochorismatase
IGB11_RS08840	COG1263	PTS System
IGB11_RS08840	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IGB11_RS08840	COG2190	(PTS) system
IGB11_RS08845	COG2188	Transcriptional regulator
IGB11_RS08850	COG0366	Alpha amylase catalytic
IGB11_RS08865	COG5632	N-Acetylmuramoyl-L-alanine amidase
IGB11_RS08865	COG5263	repeat protein
IGB11_RS08875	COG0460	homoserine dehydrogenase
IGB11_RS08890	COG1705	Flagellar rod assembly protein muramidase FlgJ
IGB11_RS08905	COG0438	transferase activity, transferring glycosyl groups
IGB11_RS08920	COG1368	sulfuric ester hydrolase activity
IGB11_RS08950	COG0431	NADPH-dependent FMN reductase
IGB11_RS08950	COG3976	FMN-binding domain protein
IGB11_RS08950	COG1053	succinate dehydrogenase
IGB11_RS08955	COG1053	succinate dehydrogenase
IGB11_RS08955	COG0431	NADPH-dependent FMN reductase
IGB11_RS08955	COG3976	FMN-binding domain protein
IGB11_RS08960	COG1686	Belongs to the peptidase S11 family
IGB11_RS08975	COG5290	Psort location Cytoplasmic, score
IGB11_RS08995	COG1126	abc transporter atp-binding protein
IGB11_RS09000	COG0765	amino acid transport
IGB11_RS09010	COG1694	Mazg nucleotide pyrophosphohydrolase
IGB11_RS09040	COG0562	UDP-galactopyranose mutase
IGB11_RS09050	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IGB11_RS09055	COG1316	TRANSCRIPTIONal
IGB11_RS09060	COG4464	protein tyrosine phosphatase activity
IGB11_RS09070	COG0489	protein tyrosine kinase activity
IGB11_RS09080	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
IGB11_RS09090	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IGB11_RS09110	COG1442	glycosyl transferase family 8
IGB11_RS09110	COG1216	Glycosyl transferase, family 2
IGB11_RS09115	COG0438	transferase activity, transferring glycosyl groups
IGB11_RS09130	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IGB11_RS09135	COG1091	dTDP-4-dehydrorhamnose reductase activity
IGB11_RS09140	COG1088	dTDP-glucose 4,6-dehydratase activity
IGB11_RS09170	COG1739	Uncharacterized protein family UPF0029
IGB11_RS09180	COG2814	Major facilitator Superfamily
IGB11_RS09190	COG1418	mRNA catabolic process
IGB11_RS09195	COG0789	Transcriptional regulator
IGB11_RS09205	COG0351	phosphomethylpyrimidine kinase
IGB11_RS09225	COG0803	Belongs to the bacterial solute-binding protein 9 family
IGB11_RS09245	COG0012	GTP binding
IGB11_RS09250	COG4481	Protein conserved in bacteria
IGB11_RS09255	COG1475	DNA binding
IGB11_RS09260	COG1192	Involved in chromosome partitioning
IGB11_RS09280	COG0584	glycerophosphoryl diester phosphodiesterase
IGB11_RS09290	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
IGB11_RS09315	COG3764	Sortase (surface protein transpeptidase)
IGB11_RS09350	COG1482	cell wall glycoprotein biosynthetic process
IGB11_RS09365	COG1131	(ABC) transporter
IGB11_RS09370	COG1725	Transcriptional regulator
IGB11_RS09380	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IGB11_RS09385	COG2213	PTS system mannitol-specific
IGB11_RS09390	COG0861	Integral membrane protein TerC family
IGB11_RS09400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IGB11_RS09405	COG1126	abc transporter atp-binding protein
IGB11_RS09410	COG0765	amino acid transport
IGB11_RS09420	COG0446	pyridine nucleotide-disulphide oxidoreductase
IGB11_RS09425	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IGB11_RS09435	COG0025	NhaP-type Na H and K H
IGB11_RS09440	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
IGB11_RS09445	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
IGB11_RS09450	COG1461	Dihydroxyacetone kinase
IGB11_RS09455	COG2376	Dihydroxyacetone kinase
IGB11_RS09460	COG2376	Dihydroxyacetone kinase
IGB11_RS09465	COG1309	transcriptional regulator
IGB11_RS09470	COG1114	Component of the transport system for branched-chain amino acids
IGB11_RS09490	COG2217	Heavy metal translocating P-type atpase
IGB11_RS09495	COG0640	Transcriptional regulator
IGB11_RS09500	COG4716	Myosin-crossreactive antigen
IGB11_RS09505	COG1428	Deoxynucleoside kinase
IGB11_RS09525	COG1846	Transcriptional regulator
IGB11_RS09530	COG1847	R3H domain protein
IGB11_RS09545	COG3590	peptidase
IGB11_RS09565	COG4720	Psort location CytoplasmicMembrane, score
IGB11_RS09610	COG0346	lactoylglutathione lyase activity
IGB11_RS09620	COG1733	regulation of RNA biosynthetic process
IGB11_RS09625	COG0390	transport system, permease component
IGB11_RS09630	COG4619	ABC transporter
IGB11_RS09640	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IGB11_RS09680	COG2040	homocysteine
IGB11_RS09685	COG0833	amino acid
IGB11_RS09695	COG4608	Belongs to the ABC transporter superfamily
IGB11_RS09700	COG0444	Belongs to the ABC transporter superfamily
IGB11_RS09705	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IGB11_RS09710	COG0601	transmembrane transport
IGB11_RS09715	COG4166	transmembrane transport
IGB11_RS09720	COG1113	amino acid transport
IGB11_RS09725	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IGB11_RS09730	COG0561	phosphatase activity
IGB11_RS09735	COG0588	phosphoglycerate mutase activity
IGB11_RS09740	COG2217	Heavy metal translocating P-type atpase
IGB11_RS09755	COG1929	Belongs to the glycerate kinase type-1 family
IGB11_RS09775	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IGB11_RS09785	COG2267	carboxylic ester hydrolase activity
IGB11_RS09805	COG2873	o-acetylhomoserine
IGB11_RS09810	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
IGB11_RS09815	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IGB11_RS09820	COG0778	Nitroreductase
IGB11_RS09835	COG1607	acyl-coa hydrolase
IGB11_RS09840	COG0492	ferredoxin-NADP+ reductase activity
IGB11_RS09855	COG0305	Participates in initiation and elongation during chromosome replication
IGB11_RS09980	COG0583	DNA-binding transcription factor activity
IGB11_RS09985	COG2855	membrane
IGB11_RS09990	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IGB11_RS09995	COG0706	membrane insertase activity
IGB11_RS10020	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IGB11_RS10040	COG2217	Heavy metal translocating P-type atpase
IGB11_RS10060	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IGB11_RS10075	COG0710	3-dehydroquinate dehydratase activity
IGB11_RS10100	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
IGB11_RS10105	COG2365	Tyrosine phosphatase family
IGB11_RS10110	COG2197	response regulator
IGB11_RS10115	COG4585	Histidine kinase
IGB11_RS10125	COG1131	(ABC) transporter
IGB11_RS10130	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IGB11_RS10135	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IGB11_RS10175	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IGB11_RS10185	COG2226	methyltransferase
IGB11_RS10245	COG1307	EDD domain protein, DegV family
IGB11_RS10275	COG0464	growth
IGB11_RS10295	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IGB11_RS10300	COG1061	Type III restriction enzyme res subunit
IGB11_RS10305	COG1002	Type II restriction enzyme, methylase subunits
IGB11_RS10310	COG1002	Type II restriction enzyme, methylase subunits
IGB11_RS10360	COG0235	Class ii aldolase
IGB11_RS10405	COG2610	gluconate transmembrane transporter activity
IGB11_RS10435	COG0673	inositol 2-dehydrogenase activity
IGB11_RS10440	COG1082	Xylose isomerase domain protein TIM barrel
IGB11_RS10445	COG0673	inositol 2-dehydrogenase activity
IGB11_RS10450	COG2814	Major facilitator Superfamily
IGB11_RS10455	COG0673	inositol 2-dehydrogenase activity
IGB11_RS10460	COG4702	Belongs to the UPF0303 family
IGB11_RS10465	COG0656	L-ascorbic acid biosynthetic process
IGB11_RS10515	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IGB11_RS10525	COG0308	aminopeptidase N
IGB11_RS10540	COG1192	Involved in chromosome partitioning
IGB11_RS10585	COG2801	Transposase and inactivated derivatives
IGB11_RS10590	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
IGB11_RS10595	COG1349	DNA-binding transcription factor activity
IGB11_RS10610	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IGB11_RS10620	COG3716	PTS system mannose fructose sorbose family IID component
IGB11_RS10625	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IGB11_RS10630	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IGB11_RS10680	COG1349	DNA-binding transcription factor activity
IGB11_RS10690	COG1070	Carbohydrate kinase
IGB11_RS10695	COG1070	Carbohydrate kinase
IGB11_RS10700	COG2814	Major facilitator Superfamily
IGB11_RS10725	COG0531	amino acid
IGB11_RS10735	COG1737	Transcriptional regulator
IGB11_RS10740	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
IGB11_RS10745	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IGB11_RS10760	COG1760	l-serine dehydratase
IGB11_RS10765	COG1760	l-serine dehydratase
IGB11_RS10770	COG2151	metal-sulfur cluster biosynthetic enzyme
IGB11_RS10780	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IGB11_RS10785	COG0436	Aminotransferase
IGB11_RS10820	COG0860	N-Acetylmuramoyl-L-alanine amidase
IGB11_RS10820	COG1388	LysM domain
IGB11_RS10860	COG1012	belongs to the aldehyde dehydrogenase family
IGB11_RS10860	COG1454	alcohol dehydrogenase
IGB11_RS10865	COG2070	2-Nitropropane dioxygenase
IGB11_RS10910	COG3730	PTS system glucitol sorbitol-specific
IGB11_RS10915	COG3732	PTS system glucitol sorbitol-specific
IGB11_RS10950	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
IGB11_RS10960	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
IGB11_RS10975	COG4166	transmembrane transport
IGB11_RS10985	COG0719	Fe-S assembly protein
IGB11_RS10990	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IGB11_RS10995	COG0822	iron-sulfur transferase activity
IGB11_RS11010	COG1882	Formate acetyltransferase
IGB11_RS11015	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IGB11_RS11090	COG2801	Transposase and inactivated derivatives
IGB11_RS11135	COG2801	Transposase and inactivated derivatives
IGB11_RS11190	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IGB11_RS11230	COG2337	Toxic component of a toxin-antitoxin (TA) module
IGB11_RS11255	COG0582	viral genome integration into host DNA
IGB11_RS11285	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IGB11_RS11370	COG0456	acetyltransferase
IGB11_RS11435	COG4372	Transposase
IGB11_RS11520	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs