locus-tag	class	description
JYQ67_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JYQ67_RS00010	COG0592	DNA-directed DNA polymerase activity
JYQ67_RS00015	COG2501	S4 domain
JYQ67_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JYQ67_RS00025	COG0187	DNA topoisomerase II activity
JYQ67_RS00045	COG0360	Binds together with S18 to 16S ribosomal RNA
JYQ67_RS00050	COG0629	single-stranded DNA binding
JYQ67_RS00055	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JYQ67_RS00065	COG0359	binds to the 23S rRNA
JYQ67_RS00070	COG0305	Participates in initiation and elongation during chromosome replication
JYQ67_RS00090	COG2826	transposase and inactivated derivatives, IS30 family
JYQ67_RS00105	COG0745	RESPONSE REGULATOR receiver
JYQ67_RS00125	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
JYQ67_RS00130	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JYQ67_RS00135	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
JYQ67_RS00140	COG1959	2 iron, 2 sulfur cluster binding
JYQ67_RS00145	COG1609	Transcriptional regulator
JYQ67_RS00155	COG1554	hydrolase, family 65, central catalytic
JYQ67_RS00160	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JYQ67_RS00170	COG1131	(ABC) transporter
JYQ67_RS00190	COG0436	Aminotransferase
JYQ67_RS00210	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
JYQ67_RS00215	COG1074	ATP-dependent DNA helicase activity
JYQ67_RS00220	COG0656	L-ascorbic acid biosynthetic process
JYQ67_RS00270	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JYQ67_RS00275	COG1012	belongs to the aldehyde dehydrogenase family
JYQ67_RS00280	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JYQ67_RS00285	COG0284	orotidine-5'-phosphate decarboxylase activity
JYQ67_RS00290	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JYQ67_RS00305	COG0438	transferase activity, transferring glycosyl groups
JYQ67_RS00335	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JYQ67_RS00340	COG1114	Component of the transport system for branched-chain amino acids
JYQ67_RS00345	COG0667	Aldo Keto reductase
JYQ67_RS00350	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
JYQ67_RS00360	COG1696	Membrane protein involved in D-alanine export
JYQ67_RS00365	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JYQ67_RS00375	COG0420	3'-5' exonuclease activity
JYQ67_RS00380	COG0419	ATPase involved in DNA repair
JYQ67_RS00390	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JYQ67_RS00405	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JYQ67_RS00410	COG0765	amino acid transport
JYQ67_RS00420	COG1113	amino acid transport
JYQ67_RS00425	COG2826	transposase and inactivated derivatives, IS30 family
JYQ67_RS00440	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JYQ67_RS00450	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JYQ67_RS00460	COG0357	Ribosomal RNA small subunit methyltransferase G
JYQ67_RS00470	COG1475	DNA binding
JYQ67_RS00475	COG4481	Protein conserved in bacteria
JYQ67_RS00480	COG0012	GTP binding
JYQ67_RS00490	COG0517	IMP dehydrogenase activity
JYQ67_RS00490	COG0516	GMP reductase activity
JYQ67_RS00505	COG0489	protein tyrosine kinase activity
JYQ67_RS00510	COG4464	protein tyrosine phosphatase activity
JYQ67_RS00525	COG1216	Glycosyl transferase, family 2
JYQ67_RS00535	COG1216	Glycosyl transferase, family 2
JYQ67_RS00545	COG0438	transferase activity, transferring glycosyl groups
JYQ67_RS00550	COG0728	peptidoglycan biosynthetic process
JYQ67_RS00560	COG3328	transposase activity
JYQ67_RS00565	COG3328	transposase activity
JYQ67_RS00570	COG0438	transferase activity, transferring glycosyl groups
JYQ67_RS00595	COG0438	transferase activity, transferring glycosyl groups
JYQ67_RS00615	COG2801	Transposase and inactivated derivatives
JYQ67_RS00630	COG2801	Transposase and inactivated derivatives
JYQ67_RS00650	COG3328	transposase activity
JYQ67_RS00665	COG0745	RESPONSE REGULATOR receiver
JYQ67_RS00675	COG1686	Belongs to the peptidase S11 family
JYQ67_RS00695	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JYQ67_RS00700	COG0675	Transposase, IS605 OrfB family
JYQ67_RS00710	COG3328	transposase activity
JYQ67_RS00725	COG0628	permease
JYQ67_RS00730	COG2759	Belongs to the formate--tetrahydrofolate ligase family
JYQ67_RS00735	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JYQ67_RS00740	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
JYQ67_RS00745	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JYQ67_RS00760	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
JYQ67_RS00765	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JYQ67_RS00770	COG0047	phosphoribosylformylglycinamidine synthase activity
JYQ67_RS00775	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JYQ67_RS00785	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
JYQ67_RS00790	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JYQ67_RS00795	COG0138	bifunctional purine biosynthesis protein purh
JYQ67_RS00800	COG0151	Belongs to the GarS family
JYQ67_RS00805	COG0588	phosphoglycerate mutase activity
JYQ67_RS00810	COG0436	Aminotransferase
JYQ67_RS00890	COG1609	Transcriptional regulator
JYQ67_RS00910	COG1942	4-Oxalocrotonate Tautomerase
JYQ67_RS00930	COG4221	oxidoreductase activity
JYQ67_RS00945	COG0667	Aldo Keto reductase
JYQ67_RS00955	COG0675	Transposase, IS605 OrfB family
JYQ67_RS00965	COG0697	spore germination
JYQ67_RS01000	COG1120	ATPase activity
JYQ67_RS01005	COG0477	Major facilitator Superfamily
JYQ67_RS01020	COG0708	Exodeoxyribonuclease III
JYQ67_RS01050	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
JYQ67_RS01060	COG2508	Transcriptional regulator
JYQ67_RS01080	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
JYQ67_RS01110	COG1063	alcohol dehydrogenase
JYQ67_RS01130	COG0583	DNA-binding transcription factor activity
JYQ67_RS01140	COG0778	Nitroreductase
JYQ67_RS01160	COG3973	AAA domain
JYQ67_RS01165	COG0248	Ppx GppA phosphatase
JYQ67_RS01180	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
JYQ67_RS01190	COG1801	Protein of unknown function DUF72
JYQ67_RS01195	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JYQ67_RS01195	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JYQ67_RS01200	COG0084	hydrolase, TatD family'
JYQ67_RS01205	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
JYQ67_RS01210	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
JYQ67_RS01215	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
JYQ67_RS01230	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JYQ67_RS01235	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JYQ67_RS01240	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JYQ67_RS01245	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JYQ67_RS01260	COG1078	dGTPase activity
JYQ67_RS01270	COG3343	RNA polymerase activity
JYQ67_RS01275	COG0504	CTP synthase activity
JYQ67_RS01280	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JYQ67_RS01285	COG0254	rRNA binding
JYQ67_RS01295	COG3764	Sortase (surface protein transpeptidase)
JYQ67_RS01310	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JYQ67_RS01315	COG1704	LemA family
JYQ67_RS01320	COG0501	Belongs to the peptidase M48B family
JYQ67_RS01325	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JYQ67_RS01335	COG0736	holo-[acyl-carrier-protein] synthase activity
JYQ67_RS01340	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JYQ67_RS01345	COG2337	Toxic component of a toxin-antitoxin (TA) module
JYQ67_RS01355	COG0193	aminoacyl-tRNA hydrolase activity
JYQ67_RS01360	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JYQ67_RS01365	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
JYQ67_RS01375	COG1098	S1 RNA binding domain
JYQ67_RS01380	COG0037	tRNA processing
JYQ67_RS01395	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
JYQ67_RS01400	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JYQ67_RS01405	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
JYQ67_RS01455	COG3328	transposase activity
JYQ67_RS01495	COG3104	oligopeptide transport
JYQ67_RS01520	COG1794	racemase activity, acting on amino acids and derivatives
JYQ67_RS01525	COG2188	Transcriptional regulator
JYQ67_RS01530	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JYQ67_RS01535	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
JYQ67_RS01540	COG2183	response to ionizing radiation
JYQ67_RS01545	COG3091	SprT-like family
JYQ67_RS01555	COG3250	beta-galactosidase activity
JYQ67_RS01560	COG3250	beta-galactosidase activity
JYQ67_RS01570	COG0588	phosphoglycerate mutase activity
JYQ67_RS01575	COG0657	acetylesterase activity
JYQ67_RS01585	COG0110	maltose O-acetyltransferase activity
JYQ67_RS01610	COG0756	dUTP diphosphatase activity
JYQ67_RS01615	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JYQ67_RS01620	COG4956	integral membrane protein (PIN domain superfamily)
JYQ67_RS01625	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JYQ67_RS01635	COG0215	cysteine-tRNA ligase activity
JYQ67_RS01640	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
JYQ67_RS01645	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JYQ67_RS01655	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JYQ67_RS01665	COG0250	Participates in transcription elongation, termination and antitermination
JYQ67_RS01670	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
JYQ67_RS01675	COG0081	regulation of translation
JYQ67_RS01680	COG2826	transposase and inactivated derivatives, IS30 family
JYQ67_RS01685	COG0531	amino acid
JYQ67_RS01690	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JYQ67_RS01695	COG0222	ribosome binding
JYQ67_RS01700	COG1271	oxidase subunit
JYQ67_RS01705	COG1294	oxidase, subunit
JYQ67_RS01710	COG4988	ABC transporter
JYQ67_RS01715	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
JYQ67_RS01720	COG1454	alcohol dehydrogenase
JYQ67_RS01720	COG1012	belongs to the aldehyde dehydrogenase family
JYQ67_RS01725	COG1114	Component of the transport system for branched-chain amino acids
JYQ67_RS01730	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JYQ67_RS01735	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JYQ67_RS01740	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
JYQ67_RS01745	COG0590	tRNA wobble adenosine to inosine editing
JYQ67_RS01755	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JYQ67_RS01760	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JYQ67_RS01765	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JYQ67_RS01775	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JYQ67_RS01780	COG3870	Protein conserved in bacteria
JYQ67_RS01785	COG0470	DNA polymerase III
JYQ67_RS01790	COG4467	Involved in initiation control of chromosome replication
JYQ67_RS01810	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
JYQ67_RS01815	COG0248	Ppx GppA phosphatase
JYQ67_RS01820	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JYQ67_RS01830	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JYQ67_RS01840	COG2235	arginine
JYQ67_RS01850	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JYQ67_RS01855	COG0436	Aminotransferase
JYQ67_RS01860	COG2826	transposase and inactivated derivatives, IS30 family
JYQ67_RS01865	COG1214	PFAM Peptidase M22, glycoprotease
JYQ67_RS01875	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JYQ67_RS01890	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JYQ67_RS01900	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JYQ67_RS01910	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
JYQ67_RS01915	COG1028	Short-chain dehydrogenase reductase Sdr
JYQ67_RS01920	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JYQ67_RS01925	COG0511	ligase activity, forming carbon-carbon bonds
JYQ67_RS01935	COG0439	Biotin carboxylase
JYQ67_RS01940	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
JYQ67_RS01945	COG0825	malonyl-CoA metabolic process
JYQ67_RS01950	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
JYQ67_RS01955	COG1268	BioY protein
JYQ67_RS01965	COG0488	(ABC) transporter
JYQ67_RS01970	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
JYQ67_RS01975	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
JYQ67_RS01980	COG0459	protein refolding
JYQ67_RS01985	COG0531	amino acid
JYQ67_RS02000	COG1739	Uncharacterized protein family UPF0029
JYQ67_RS02005	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
JYQ67_RS02020	COG0653	protein targeting
JYQ67_RS02035	COG1950	PFAM Membrane protein of
JYQ67_RS02040	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
JYQ67_RS02045	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JYQ67_RS02050	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
JYQ67_RS02060	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JYQ67_RS02065	COG0436	Aminotransferase
JYQ67_RS02070	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JYQ67_RS02080	COG0675	Transposase, IS605 OrfB family
JYQ67_RS02095	COG2801	Transposase and inactivated derivatives
JYQ67_RS02100	COG0492	ferredoxin-NADP+ reductase activity
JYQ67_RS02105	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
JYQ67_RS02110	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JYQ67_RS02115	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JYQ67_RS02125	COG0561	phosphatase activity
JYQ67_RS02135	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JYQ67_RS02150	COG0556	nucleotide-excision repair
JYQ67_RS02155	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JYQ67_RS02165	COG1660	Displays ATPase and GTPase activities
JYQ67_RS02170	COG0391	Required for morphogenesis under gluconeogenic growth conditions
JYQ67_RS02175	COG1481	regulation of sporulation
JYQ67_RS02185	COG0740	serine-type endopeptidase activity
JYQ67_RS02255	COG2801	Transposase and inactivated derivatives
JYQ67_RS02275	COG0126	phosphoglycerate kinase activity
JYQ67_RS02280	COG0149	triose-phosphate isomerase activity
JYQ67_RS02285	COG0148	phosphopyruvate hydratase activity
JYQ67_RS02290	COG1113	amino acid transport
JYQ67_RS02305	COG0557	exoribonuclease II activity
JYQ67_RS02310	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
JYQ67_RS02320	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
JYQ67_RS02325	COG0280	phosphate acetyltransferase
JYQ67_RS02330	COG0802	atpase or kinase
JYQ67_RS02340	COG2176	DNA-directed DNA polymerase activity
JYQ67_RS02345	COG0812	UDP-N-acetylmuramate dehydrogenase activity
JYQ67_RS02360	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JYQ67_RS02365	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JYQ67_RS02375	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
JYQ67_RS02375	COG2755	lipolytic protein G-D-S-L family
JYQ67_RS02380	COG0561	phosphatase activity
JYQ67_RS02385	COG3942	CHAP domain
JYQ67_RS02385	COG1388	LysM domain
JYQ67_RS02390	COG2855	membrane
JYQ67_RS02395	COG0583	DNA-binding transcription factor activity
JYQ67_RS02400	COG1482	cell wall glycoprotein biosynthetic process
JYQ67_RS02405	COG1307	EDD domain protein, DegV family
JYQ67_RS02425	COG3715	PTS system
JYQ67_RS02430	COG3716	PTS system mannose fructose sorbose family IID component
JYQ67_RS02445	COG0745	RESPONSE REGULATOR receiver
JYQ67_RS02450	COG5002	protein histidine kinase activity
JYQ67_RS02450	COG3850	Histidine kinase
JYQ67_RS02455	COG4975	Glucose uptake
JYQ67_RS02465	COG2801	Transposase and inactivated derivatives
JYQ67_RS02475	COG0675	Transposase, IS605 OrfB family
JYQ67_RS02480	COG0450	alkyl hydroperoxide reductase
JYQ67_RS02510	COG0656	L-ascorbic acid biosynthetic process
JYQ67_RS02515	COG0149	triose-phosphate isomerase activity
JYQ67_RS02520	COG3527	Alpha-acetolactate decarboxylase
JYQ67_RS02555	COG1132	(ABC) transporter
JYQ67_RS02560	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JYQ67_RS02575	COG3442	glutamine amidotransferase
JYQ67_RS02580	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JYQ67_RS02585	COG1435	thymidine kinase activity
JYQ67_RS02590	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JYQ67_RS02595	COG2890	protein-(glutamine-N5) methyltransferase activity
JYQ67_RS02600	COG0009	L-threonylcarbamoyladenylate synthase
JYQ67_RS02605	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JYQ67_RS02610	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JYQ67_RS02630	COG2233	PERMEase
JYQ67_RS02635	COG0356	it plays a direct role in the translocation of protons across the membrane
JYQ67_RS02640	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JYQ67_RS02645	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JYQ67_RS02650	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JYQ67_RS02655	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JYQ67_RS02660	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JYQ67_RS02665	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JYQ67_RS02670	COG0355	proton-transporting ATP synthase activity, rotational mechanism
JYQ67_RS02680	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JYQ67_RS02685	COG1077	Cell shape determining protein MreB Mrl
JYQ67_RS02690	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
JYQ67_RS02700	COG0772	Belongs to the SEDS family
JYQ67_RS02715	COG1181	Belongs to the D-alanine--D-alanine ligase family
JYQ67_RS02725	COG0589	response to stress
JYQ67_RS02735	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JYQ67_RS02755	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JYQ67_RS02770	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JYQ67_RS02775	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
JYQ67_RS02780	COG1104	cysteine desulfurase activity
JYQ67_RS02785	COG0301	tRNA thio-modification
JYQ67_RS02790	COG2610	gluconate transmembrane transporter activity
JYQ67_RS02795	COG1929	Belongs to the glycerate kinase type-1 family
JYQ67_RS02830	COG0675	Transposase, IS605 OrfB family
JYQ67_RS02845	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
JYQ67_RS02850	COG0525	valine-tRNA ligase activity
JYQ67_RS02855	COG0285	dihydrofolate synthase activity
JYQ67_RS02870	COG1077	Cell shape determining protein MreB Mrl
JYQ67_RS02875	COG1792	Involved in formation and maintenance of cell shape
JYQ67_RS02885	COG0765	amino acid transport
JYQ67_RS02890	COG1126	abc transporter atp-binding protein
JYQ67_RS02895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JYQ67_RS02900	COG0612	Peptidase, M16
JYQ67_RS02905	COG0612	Peptidase, M16
JYQ67_RS02910	COG1426	Protein conserved in bacteria
JYQ67_RS02915	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JYQ67_RS02920	COG1058	Belongs to the CinA family
JYQ67_RS02920	COG1546	Belongs to the CinA family
JYQ67_RS02925	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JYQ67_RS02935	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JYQ67_RS02940	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JYQ67_RS02945	COG0632	four-way junction helicase activity
JYQ67_RS02950	COG2255	four-way junction helicase activity
JYQ67_RS02965	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
JYQ67_RS02970	COG0513	Belongs to the DEAD box helicase family
JYQ67_RS02975	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JYQ67_RS02980	COG4472	Bacterial protein of unknown function (DUF965)
JYQ67_RS02985	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JYQ67_RS02990	COG3906	Belongs to the UPF0473 family
JYQ67_RS02995	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JYQ67_RS03005	COG1193	negative regulation of DNA recombination
JYQ67_RS03010	COG3118	belongs to the thioredoxin family
JYQ67_RS03025	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
JYQ67_RS03030	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JYQ67_RS03035	COG0622	Phosphoesterase
JYQ67_RS03040	COG0561	phosphatase activity
JYQ67_RS03045	COG0668	transmembrane transport
JYQ67_RS03060	COG0006	proline dipeptidase activity
JYQ67_RS03065	COG1609	Transcriptional regulator
JYQ67_RS03075	COG0217	transcriptional regulatory protein
JYQ67_RS03080	COG0791	NLP P60 protein
JYQ67_RS03080	COG1388	LysM domain
JYQ67_RS03090	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JYQ67_RS03100	COG4537	Required for transformation and DNA binding
JYQ67_RS03120	COG0827	DNA restriction-modification system
JYQ67_RS03125	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JYQ67_RS03135	COG4470	Protein conserved in bacteria
JYQ67_RS03140	COG0647	UMP catabolic process
JYQ67_RS03150	COG0586	Pfam SNARE associated Golgi protein
JYQ67_RS03270	COG1393	Belongs to the ArsC family
JYQ67_RS03275	COG4862	establishment of competence for transformation
JYQ67_RS03290	COG2357	RelA SpoT domain protein
JYQ67_RS03295	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JYQ67_RS03300	COG0564	pseudouridine synthase activity
JYQ67_RS03305	COG2706	6-phosphogluconolactonase activity
JYQ67_RS03310	COG0500	methyltransferase
JYQ67_RS03320	COG1674	ftsk spoiiie
JYQ67_RS03335	COG2001	Belongs to the MraZ family
JYQ67_RS03340	COG0275	rRNA processing
JYQ67_RS03350	COG0768	penicillin binding
JYQ67_RS03355	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JYQ67_RS03360	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JYQ67_RS03365	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JYQ67_RS03375	COG0849	cell division
JYQ67_RS03380	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JYQ67_RS03385	COG1799	cell septum assembly
JYQ67_RS03400	COG3599	regulation of cell shape
JYQ67_RS03405	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JYQ67_RS03410	COG1278	Cold shock
JYQ67_RS03425	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JYQ67_RS03435	COG0482	sulfurtransferase activity
JYQ67_RS03450	COG0406	alpha-ribazole phosphatase activity
JYQ67_RS03460	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
JYQ67_RS03465	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JYQ67_RS03470	COG1393	Belongs to the ArsC family
JYQ67_RS03475	COG1597	lipid kinase activity
JYQ67_RS03480	COG5503	Protein of unknown function (DUF1447)
JYQ67_RS03490	COG0242	peptide deformylase activity
JYQ67_RS03495	COG4476	Belongs to the UPF0223 family
JYQ67_RS03500	COG0483	inositol monophosphate 1-phosphatase activity
JYQ67_RS03505	COG1217	gtp-binding protein TYPA
JYQ67_RS03515	COG4471	UPF0298 protein
JYQ67_RS03520	COG0742	ribosomal rna small subunit methyltransferase
JYQ67_RS03525	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JYQ67_RS03530	COG3480	Lon protease (S16) C-terminal proteolytic domain
JYQ67_RS03535	COG1596	polysaccharide export
JYQ67_RS03535	COG1555	photosystem II stabilization
JYQ67_RS03540	COG2131	deaminase
JYQ67_RS03545	COG2333	competence protein COMEC
JYQ67_RS03545	COG0658	competence protein
JYQ67_RS03550	COG1466	dna polymerase III delta subunit
JYQ67_RS03555	COG0268	Binds directly to 16S ribosomal RNA
JYQ67_RS03560	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
JYQ67_RS03590	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JYQ67_RS03595	COG0544	peptidyl-prolyl cis-trans isomerase activity
JYQ67_RS03600	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JYQ67_RS03605	COG0218	Necessary for normal cell division and for the maintenance of normal septation
JYQ67_RS03620	COG1126	abc transporter atp-binding protein
JYQ67_RS03625	COG0322	excinuclease ABC activity
JYQ67_RS03630	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JYQ67_RS03635	COG1234	tRNA 3'-trailer cleavage
JYQ67_RS03640	COG0300	oxidoreductase activity
JYQ67_RS03645	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
JYQ67_RS03645	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
JYQ67_RS03650	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JYQ67_RS03660	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JYQ67_RS03675	COG2249	NAD(P)H dehydrogenase (quinone) activity
JYQ67_RS03695	COG1396	sequence-specific DNA binding
JYQ67_RS03710	COG1028	Short-chain dehydrogenase reductase Sdr
JYQ67_RS03735	COG2814	Major facilitator Superfamily
JYQ67_RS03745	COG0367	asparagine synthase
JYQ67_RS03845	COG1393	Belongs to the ArsC family
JYQ67_RS03900	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JYQ67_RS03935	COG4152	abc transporter atp-binding protein
JYQ67_RS03975	COG2801	Transposase and inactivated derivatives
JYQ67_RS04045	COG2217	Heavy metal translocating P-type atpase
JYQ67_RS04070	COG2814	Major facilitator Superfamily
JYQ67_RS04090	COG0446	pyridine nucleotide-disulphide oxidoreductase
JYQ67_RS04185	COG1396	sequence-specific DNA binding
JYQ67_RS04195	COG3646	Phage regulatory protein
JYQ67_RS04195	COG3645	SOS response
JYQ67_RS04245	COG0629	single-stranded DNA binding
JYQ67_RS04315	COG2801	Transposase and inactivated derivatives
JYQ67_RS04335	COG1196	nuclear chromosome segregation
JYQ67_RS04350	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
JYQ67_RS04355	COG2826	transposase and inactivated derivatives, IS30 family
JYQ67_RS04365	COG2826	transposase and inactivated derivatives, IS30 family
JYQ67_RS04375	COG3328	transposase activity
JYQ67_RS04400	COG1556	Lactate utilization protein
JYQ67_RS04405	COG1139	Iron-sulfur cluster binding protein
JYQ67_RS04410	COG0247	lactate metabolic process
JYQ67_RS04415	COG3425	synthase
JYQ67_RS04420	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JYQ67_RS04425	COG4224	UPF0291 protein
JYQ67_RS04430	COG3763	UPF0154 protein
JYQ67_RS04435	COG0204	Acyl-transferase
JYQ67_RS04440	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
JYQ67_RS04445	COG2827	Endonuclease containing a URI domain
JYQ67_RS04450	COG0052	Belongs to the universal ribosomal protein uS2 family
JYQ67_RS04455	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JYQ67_RS04465	COG0233	cytoplasmic translational termination
JYQ67_RS04470	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JYQ67_RS04475	COG4589	Belongs to the CDS family
JYQ67_RS04480	COG0750	zinc metalloprotease
JYQ67_RS04485	COG0442	prolyl-tRNA aminoacylation
JYQ67_RS04490	COG2176	DNA-directed DNA polymerase activity
JYQ67_RS04495	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JYQ67_RS04500	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
JYQ67_RS04505	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
JYQ67_RS04510	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
JYQ67_RS04515	COG0505	Belongs to the CarA family
JYQ67_RS04520	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JYQ67_RS04525	COG0779	Required for maturation of 30S ribosomal subunits
JYQ67_RS04530	COG0195	Participates in both transcription termination and antitermination
JYQ67_RS04535	COG2740	Nucleic-acid-binding protein implicated in transcription termination
JYQ67_RS04545	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JYQ67_RS04550	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JYQ67_RS04555	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JYQ67_RS04560	COG0196	riboflavin kinase activity
JYQ67_RS04565	COG2814	Major facilitator Superfamily
JYQ67_RS04590	COG3328	transposase activity
JYQ67_RS04595	COG2801	Transposase and inactivated derivatives
JYQ67_RS04620	COG1609	Transcriptional regulator
JYQ67_RS04625	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JYQ67_RS04665	COG3759	membrane
JYQ67_RS04690	COG2801	Transposase and inactivated derivatives
JYQ67_RS04700	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JYQ67_RS04725	COG1420	regulation of RNA biosynthetic process
JYQ67_RS04730	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JYQ67_RS04735	COG0443	Heat shock 70 kDa protein
JYQ67_RS04740	COG0484	heat shock protein binding
JYQ67_RS04755	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
JYQ67_RS04760	COG0140	phosphoribosyl-ATP diphosphatase activity
JYQ67_RS04765	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JYQ67_RS04770	COG0481	GTPase activity
JYQ67_RS04780	COG0406	alpha-ribazole phosphatase activity
JYQ67_RS04785	COG0667	Aldo Keto reductase
JYQ67_RS04790	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
JYQ67_RS04795	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JYQ67_RS04810	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
JYQ67_RS04820	COG0307	riboflavin synthase, alpha
JYQ67_RS04825	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JYQ67_RS04825	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JYQ67_RS04835	COG5002	protein histidine kinase activity
JYQ67_RS04840	COG0745	RESPONSE REGULATOR receiver
JYQ67_RS04850	COG1104	cysteine desulfurase activity
JYQ67_RS04870	COG1811	Na channel or pump
JYQ67_RS04875	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JYQ67_RS04885	COG1464	Belongs to the NlpA lipoprotein family
JYQ67_RS04890	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JYQ67_RS04905	COG0351	phosphomethylpyrimidine kinase
JYQ67_RS04910	COG0352	thiamine-phosphate diphosphorylase activity
JYQ67_RS04915	COG0351	phosphomethylpyrimidine kinase
JYQ67_RS04920	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
JYQ67_RS04935	COG1518	maintenance of DNA repeat elements
JYQ67_RS04955	COG0657	acetylesterase activity
JYQ67_RS04985	COG0039	L-malate dehydrogenase activity
JYQ67_RS04995	COG2264	protein methyltransferase activity
JYQ67_RS05000	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JYQ67_RS05010	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JYQ67_RS05015	COG1490	D-aminoacyl-tRNA deacylase activity
JYQ67_RS05025	COG0626	cystathionine gamma-synthase activity
JYQ67_RS05030	COG0626	cystathionine gamma-synthase activity
JYQ67_RS05035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JYQ67_RS05040	COG0456	acetyltransferase
JYQ67_RS05045	COG0765	amino acid transport
JYQ67_RS05050	COG1126	abc transporter atp-binding protein
JYQ67_RS05055	COG1473	amidohydrolase
JYQ67_RS05060	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JYQ67_RS05065	COG2079	MmgE PrpD family protein
JYQ67_RS05070	COG0765	amino acid transport
JYQ67_RS05075	COG0765	amino acid transport
JYQ67_RS05080	COG1126	abc transporter atp-binding protein
JYQ67_RS05095	COG0460	homoserine dehydrogenase
JYQ67_RS05100	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
JYQ67_RS05105	COG0833	amino acid
JYQ67_RS05110	COG2040	homocysteine
JYQ67_RS05115	COG3001	Fructosamine kinase
JYQ67_RS05120	COG0860	N-Acetylmuramoyl-L-alanine amidase
JYQ67_RS05130	COG0124	histidyl-tRNA synthetase
JYQ67_RS05135	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
JYQ67_RS05145	COG0828	Belongs to the bacterial ribosomal protein bS21 family
JYQ67_RS05150	COG1610	YqeY-like protein
JYQ67_RS05155	COG1702	phosphate starvation-inducible protein PhoH
JYQ67_RS05160	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JYQ67_RS05165	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
JYQ67_RS05170	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JYQ67_RS05175	COG1381	Involved in DNA repair and RecF pathway recombination
JYQ67_RS05180	COG0752	glycyl-tRNA synthetase alpha subunit
JYQ67_RS05185	COG0751	glycine-tRNA ligase activity
JYQ67_RS05190	COG0358	DNA primase activity
JYQ67_RS05195	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JYQ67_RS05210	COG2801	Transposase and inactivated derivatives
JYQ67_RS05235	COG2261	transglycosylase associated protein
JYQ67_RS05245	COG2826	transposase and inactivated derivatives, IS30 family
JYQ67_RS05265	COG0527	aspartate kinase activity
JYQ67_RS05270	COG0019	diaminopimelate decarboxylase activity
JYQ67_RS05275	COG2171	N-acyltransferase activity
JYQ67_RS05280	COG1473	amidohydrolase
JYQ67_RS05285	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JYQ67_RS05290	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JYQ67_RS05295	COG0436	Aminotransferase
JYQ67_RS05300	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JYQ67_RS05305	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JYQ67_RS05310	COG0569	domain protein
JYQ67_RS05315	COG2384	SAM-dependent methyltransferase
JYQ67_RS05320	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JYQ67_RS05325	COG2195	Cleaves the N-terminal amino acid of tripeptides
JYQ67_RS05335	COG0587	DNA-directed DNA polymerase activity
JYQ67_RS05360	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
JYQ67_RS05365	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JYQ67_RS05370	COG1187	pseudouridine synthase activity
JYQ67_RS05375	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
JYQ67_RS05385	COG0514	ATP-dependent DNA helicase (RecQ)
JYQ67_RS05395	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
JYQ67_RS05400	COG0539	negative regulation of cytoplasmic translation
JYQ67_RS05405	COG1160	GTP binding
JYQ67_RS05415	COG0457	Tetratricopeptide repeat
JYQ67_RS05425	COG0617	tRNA 3'-terminal CCA addition
JYQ67_RS05430	COG0488	(ABC) transporter
JYQ67_RS05435	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
JYQ67_RS05440	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JYQ67_RS05445	COG1272	protein, Hemolysin III
JYQ67_RS05450	COG1307	EDD domain protein, DegV family
JYQ67_RS05455	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JYQ67_RS05465	COG2755	lipolytic protein G-D-S-L family
JYQ67_RS05470	COG4698	Protein conserved in bacteria
JYQ67_RS05475	COG4479	Belongs to the UPF0346 family
JYQ67_RS05480	COG3328	transposase activity
JYQ67_RS05550	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JYQ67_RS05555	COG0758	DNA mediated transformation
JYQ67_RS05560	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JYQ67_RS05575	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
JYQ67_RS05580	COG0187	DNA topoisomerase II activity
JYQ67_RS05585	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JYQ67_RS05605	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JYQ67_RS05615	COG1956	GAF domain-containing protein
JYQ67_RS05625	COG0402	S-adenosylhomocysteine deaminase activity
JYQ67_RS05640	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JYQ67_RS05645	COG1811	Na channel or pump
JYQ67_RS05650	COG2223	nitrite transmembrane transporter activity
JYQ67_RS05665	COG2814	Major facilitator Superfamily
JYQ67_RS05690	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JYQ67_RS05695	COG0110	maltose O-acetyltransferase activity
JYQ67_RS05700	COG0110	maltose O-acetyltransferase activity
JYQ67_RS05720	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JYQ67_RS05730	COG2423	ornithine cyclodeaminase activity
JYQ67_RS05775	COG0656	L-ascorbic acid biosynthetic process
JYQ67_RS05780	COG4720	Psort location CytoplasmicMembrane, score
JYQ67_RS05790	COG0538	isocitrate dehydrogenase activity
JYQ67_RS05800	COG4974	Belongs to the 'phage' integrase family
JYQ67_RS05805	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
JYQ67_RS05810	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
JYQ67_RS05825	COG1063	alcohol dehydrogenase
JYQ67_RS05850	COG1732	Glycine betaine
JYQ67_RS05880	COG3328	transposase activity
JYQ67_RS05890	COG2814	Major facilitator Superfamily
JYQ67_RS05925	COG4975	Glucose uptake
JYQ67_RS05935	COG4975	Glucose uptake
JYQ67_RS05940	COG1609	Transcriptional regulator
JYQ67_RS05945	COG2801	Transposase and inactivated derivatives
JYQ67_RS06030	COG0318	PFAM AMP-dependent synthetase and ligase
JYQ67_RS06035	COG2271	Major facilitator Superfamily
JYQ67_RS06045	COG0626	cystathionine gamma-synthase activity
JYQ67_RS06050	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JYQ67_RS06060	COG2848	UPF0210 protein
JYQ67_RS06085	COG2826	transposase and inactivated derivatives, IS30 family
JYQ67_RS06100	COG0697	spore germination
JYQ67_RS06110	COG1053	succinate dehydrogenase
JYQ67_RS06110	COG3976	FMN-binding domain protein
JYQ67_RS06115	COG0583	DNA-binding transcription factor activity
JYQ67_RS06125	COG0183	Belongs to the thiolase family
JYQ67_RS06130	COG0628	permease
JYQ67_RS06135	COG0730	response to heat
JYQ67_RS06140	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
JYQ67_RS06145	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JYQ67_RS06170	COG1250	3-hydroxyacyl-CoA dehydrogenase
JYQ67_RS06180	COG4690	dipeptidase activity
JYQ67_RS06190	COG2826	transposase and inactivated derivatives, IS30 family
JYQ67_RS06195	COG1113	amino acid transport
JYQ67_RS06205	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
JYQ67_RS06225	COG0105	UTP biosynthetic process
JYQ67_RS06230	COG1695	Transcriptional regulator
JYQ67_RS06235	COG3479	Phenolic acid decarboxylase
JYQ67_RS06255	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JYQ67_RS06260	COG2918	glutathione biosynthetic process
JYQ67_RS06260	COG1181	Belongs to the D-alanine--D-alanine ligase family
JYQ67_RS06265	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JYQ67_RS06270	COG0402	S-adenosylhomocysteine deaminase activity
JYQ67_RS06275	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JYQ67_RS06315	COG2801	Transposase and inactivated derivatives
JYQ67_RS06325	COG0390	transport system, permease component
JYQ67_RS06335	COG0028	Belongs to the TPP enzyme family
JYQ67_RS06370	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JYQ67_RS06370	COG1263	PTS System
JYQ67_RS06370	COG2190	(PTS) system
JYQ67_RS06375	COG2188	Transcriptional regulator
JYQ67_RS06380	COG0366	Alpha amylase catalytic
JYQ67_RS06405	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JYQ67_RS06450	COG0582	viral genome integration into host DNA
JYQ67_RS06470	COG2801	Transposase and inactivated derivatives
JYQ67_RS06475	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JYQ67_RS06485	COG1397	ADP-ribosylglycohydrolase
JYQ67_RS06515	COG2610	gluconate transmembrane transporter activity
JYQ67_RS06520	COG1609	Transcriptional regulator
JYQ67_RS06530	COG0436	Aminotransferase
JYQ67_RS06565	COG2181	nitrate reductase activity
JYQ67_RS06575	COG1140	nitrate reductase beta subunit
JYQ67_RS06580	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
JYQ67_RS06585	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JYQ67_RS06600	COG0315	cyclic pyranopterin monophosphate synthase activity
JYQ67_RS06625	COG2197	response regulator
JYQ67_RS06650	COG2226	methyltransferase
JYQ67_RS06660	COG2151	metal-sulfur cluster biosynthetic enzyme
JYQ67_RS06665	COG2223	nitrite transmembrane transporter activity
JYQ67_RS06670	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JYQ67_RS06690	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JYQ67_RS06695	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
JYQ67_RS06700	COG1252	NADH dehydrogenase
JYQ67_RS06705	COG2151	metal-sulfur cluster biosynthetic enzyme
JYQ67_RS06725	COG2826	transposase and inactivated derivatives, IS30 family
JYQ67_RS06735	COG0719	Fe-S assembly protein
JYQ67_RS06740	COG0822	iron-sulfur transferase activity
JYQ67_RS06745	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JYQ67_RS06750	COG0719	Fe-S assembly protein
JYQ67_RS06785	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JYQ67_RS06790	COG0436	Aminotransferase
JYQ67_RS06795	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JYQ67_RS06800	COG0287	Prephenate dehydrogenase
JYQ67_RS06805	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
JYQ67_RS06815	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
JYQ67_RS06820	COG1605	Chorismate mutase
JYQ67_RS06820	COG0077	Prephenate dehydratase
JYQ67_RS06825	COG0738	Major facilitator superfamily
JYQ67_RS06830	COG3104	oligopeptide transport
JYQ67_RS06840	COG0561	phosphatase activity
JYQ67_RS06855	COG0477	Major facilitator Superfamily
JYQ67_RS06885	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JYQ67_RS06890	COG1942	4-Oxalocrotonate Tautomerase
JYQ67_RS06895	COG0475	glutathione-regulated potassium exporter activity
JYQ67_RS06895	COG0569	domain protein
JYQ67_RS06910	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JYQ67_RS06915	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JYQ67_RS06925	COG0477	Major facilitator Superfamily
JYQ67_RS06935	COG1253	flavin adenine dinucleotide binding
JYQ67_RS06940	COG2814	Major facilitator Superfamily
JYQ67_RS06955	COG0583	DNA-binding transcription factor activity
JYQ67_RS06965	COG0095	Lipoate-protein ligase
JYQ67_RS07000	COG1687	branched-chain amino acid
JYQ67_RS07015	COG0460	homoserine dehydrogenase
JYQ67_RS07020	COG0083	homoserine kinase activity
JYQ67_RS07030	COG0702	epimerase
JYQ67_RS07035	COG1418	mRNA catabolic process
JYQ67_RS07040	COG3022	response to hydroperoxide
JYQ67_RS07050	COG1307	EDD domain protein, DegV family
JYQ67_RS07055	COG1293	RNA-binding protein homologous to eukaryotic snRNP
JYQ67_RS07070	COG3328	transposase activity
JYQ67_RS07080	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JYQ67_RS07085	COG0505	Belongs to the CarA family
JYQ67_RS07090	COG0564	pseudouridine synthase activity
JYQ67_RS07105	COG0328	RNA-DNA hybrid ribonuclease activity
JYQ67_RS07115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JYQ67_RS07120	COG0765	amino acid transport
JYQ67_RS07125	COG1442	glycosyl transferase family 8
JYQ67_RS07125	COG1216	Glycosyl transferase, family 2
JYQ67_RS07145	COG0154	amidase activity
JYQ67_RS07155	COG0116	Belongs to the methyltransferase superfamily
JYQ67_RS07160	COG1051	belongs to the nudix hydrolase family
JYQ67_RS07180	COG3599	regulation of cell shape
JYQ67_RS07185	COG4474	Belongs to the UPF0398 family
JYQ67_RS07190	COG3331	DNA recombination
JYQ67_RS07200	COG0697	spore germination
JYQ67_RS07205	COG0667	Aldo Keto reductase
JYQ67_RS07230	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JYQ67_RS07230	COG1199	ATP-dependent helicase activity
JYQ67_RS07255	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JYQ67_RS07260	COG0675	Transposase, IS605 OrfB family
JYQ67_RS07270	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
JYQ67_RS07270	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JYQ67_RS07275	COG0561	phosphatase activity
JYQ67_RS07290	COG2801	Transposase and inactivated derivatives
JYQ67_RS07330	COG2261	transglycosylase associated protein
JYQ67_RS07390	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JYQ67_RS07400	COG0028	Belongs to the TPP enzyme family
JYQ67_RS07415	COG0167	dihydroorotate dehydrogenase activity
JYQ67_RS07420	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JYQ67_RS07425	COG0505	Belongs to the CarA family
JYQ67_RS07430	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JYQ67_RS07440	COG4336	lyase activity
JYQ67_RS07495	COG0163	prenyltransferase activity
JYQ67_RS07530	COG1518	maintenance of DNA repeat elements
JYQ67_RS07545	COG1857	crispr-associated protein
JYQ67_RS07565	COG0335	large ribosomal subunit rRNA binding
JYQ67_RS07570	COG0531	amino acid
JYQ67_RS07575	COG0336	Belongs to the RNA methyltransferase TrmD family
JYQ67_RS07580	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JYQ67_RS07585	COG1837	Belongs to the UPF0109 family
JYQ67_RS07590	COG0228	four-way junction DNA binding
JYQ67_RS07600	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JYQ67_RS07605	COG0581	inorganic phosphate transmembrane transporter activity
JYQ67_RS07610	COG0573	inorganic phosphate transmembrane transporter activity
JYQ67_RS07615	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
JYQ67_RS07620	COG0745	RESPONSE REGULATOR receiver
JYQ67_RS07635	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JYQ67_RS07640	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
JYQ67_RS07645	COG0552	protein localization to endoplasmic reticulum
JYQ67_RS07650	COG1196	nuclear chromosome segregation
JYQ67_RS07655	COG0571	ribonuclease III activity
JYQ67_RS07660	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JYQ67_RS07665	COG0416	fatty acid biosynthetic process
JYQ67_RS07670	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JYQ67_RS07675	COG1461	Dihydroxyacetone kinase
JYQ67_RS07685	COG0227	Belongs to the bacterial ribosomal protein bL28 family
JYQ67_RS07690	COG1564	THIamine pyrophosphokinase
JYQ67_RS07695	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JYQ67_RS07700	COG1162	GTPase activity
JYQ67_RS07705	COG0515	serine threonine protein kinase
JYQ67_RS07705	COG2815	serine threonine protein kinase
JYQ67_RS07715	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JYQ67_RS07715	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JYQ67_RS07720	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JYQ67_RS07725	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JYQ67_RS07730	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JYQ67_RS07735	COG1758	RNA polymerase activity
JYQ67_RS07750	COG0497	DNA recombination
JYQ67_RS07755	COG1438	arginine binding
JYQ67_RS07760	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
JYQ67_RS07775	COG1570	exodeoxyribonuclease VII activity
JYQ67_RS07780	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JYQ67_RS07785	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JYQ67_RS07790	COG1302	Protein conserved in bacteria
JYQ67_RS07795	COG0006	proline dipeptidase activity
JYQ67_RS07800	COG0211	Belongs to the bacterial ribosomal protein bL27 family
JYQ67_RS07810	COG0261	This protein binds to 23S rRNA in the presence of protein L20
JYQ67_RS07815	COG1309	transcriptional regulator
JYQ67_RS07845	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JYQ67_RS07855	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JYQ67_RS07860	COG1940	carbohydrate kinase activity
JYQ67_RS07875	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JYQ67_RS07880	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JYQ67_RS07885	COG0768	penicillin binding
JYQ67_RS07895	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JYQ67_RS07900	COG0572	uridine kinase
JYQ67_RS07905	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JYQ67_RS07905	COG0072	phenylalanine-tRNA ligase activity
JYQ67_RS07910	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JYQ67_RS07915	COG1733	regulation of RNA biosynthetic process
JYQ67_RS07925	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JYQ67_RS07930	COG1254	Belongs to the acylphosphatase family
JYQ67_RS07935	COG0706	membrane insertase activity
JYQ67_RS07940	COG0242	peptide deformylase activity
JYQ67_RS07950	COG5002	protein histidine kinase activity
JYQ67_RS07955	COG0745	RESPONSE REGULATOR receiver
JYQ67_RS07960	COG0333	Belongs to the bacterial ribosomal protein bL32 family
JYQ67_RS07970	COG1323	Belongs to the UPF0348 family
JYQ67_RS07975	COG2226	methyltransferase
JYQ67_RS07980	COG0799	negative regulation of ribosome biogenesis
JYQ67_RS07990	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JYQ67_RS08000	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JYQ67_RS08015	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
JYQ67_RS08020	COG0291	Belongs to the bacterial ribosomal protein bL35 family
JYQ67_RS08025	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
JYQ67_RS08030	COG1484	DNA-dependent DNA replication
JYQ67_RS08040	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JYQ67_RS08045	COG0237	dephospho-CoA kinase activity
JYQ67_RS08050	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
JYQ67_RS08065	COG0670	Belongs to the BI1 family
JYQ67_RS08070	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JYQ67_RS08075	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JYQ67_RS08080	COG3118	belongs to the thioredoxin family
JYQ67_RS08090	COG0220	tRNA (guanine-N7-)-methyltransferase activity
JYQ67_RS08100	COG1131	(ABC) transporter
JYQ67_RS08105	COG0537	adenosine 5'-monophosphoramidase activity
JYQ67_RS08120	COG3481	metal-dependent phosphohydrolase, HD sub domain
JYQ67_RS08125	COG3679	Belongs to the UPF0342 family
JYQ67_RS08130	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JYQ67_RS08135	COG0018	arginyl-trna synthetase
JYQ67_RS08155	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JYQ67_RS08160	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JYQ67_RS08170	COG0302	gtp cyclohydrolase
JYQ67_RS08175	COG0302	gtp cyclohydrolase
JYQ67_RS08175	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JYQ67_RS08190	COG1609	Transcriptional regulator
JYQ67_RS08200	COG1428	Deoxynucleoside kinase
JYQ67_RS08205	COG1705	Flagellar rod assembly protein muramidase FlgJ
JYQ67_RS08205	COG1388	LysM domain
JYQ67_RS08215	COG0589	response to stress
JYQ67_RS08220	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JYQ67_RS08225	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
JYQ67_RS08235	COG2244	polysaccharide biosynthetic process
JYQ67_RS08245	COG0495	leucyl-tRNA aminoacylation
JYQ67_RS08250	COG0671	phosphoesterase, PA-phosphatase related
JYQ67_RS08255	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JYQ67_RS08260	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JYQ67_RS08265	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JYQ67_RS08275	COG2818	Glycosylase
JYQ67_RS08280	COG2814	Major facilitator Superfamily
JYQ67_RS08290	COG1113	amino acid transport
JYQ67_RS08330	COG1607	acyl-coa hydrolase
JYQ67_RS08345	COG2233	PERMEase
JYQ67_RS08355	COG0602	queuosine metabolic process
JYQ67_RS08365	COG0765	amino acid transport
JYQ67_RS08370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JYQ67_RS08375	COG2076	Multidrug Resistance protein
JYQ67_RS08390	COG2826	transposase and inactivated derivatives, IS30 family
JYQ67_RS08475	COG0438	transferase activity, transferring glycosyl groups
JYQ67_RS08480	COG0438	transferase activity, transferring glycosyl groups
JYQ67_RS08485	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JYQ67_RS08500	COG0542	response to heat
JYQ67_RS08510	COG1335	isochorismatase
JYQ67_RS08515	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JYQ67_RS08530	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JYQ67_RS08545	COG2826	transposase and inactivated derivatives, IS30 family
JYQ67_RS08565	COG1131	(ABC) transporter
JYQ67_RS08570	COG2188	Transcriptional regulator
JYQ67_RS08575	COG1088	dTDP-glucose 4,6-dehydratase activity
JYQ67_RS08585	COG1215	transferase activity, transferring glycosyl groups
JYQ67_RS08590	COG0438	transferase activity, transferring glycosyl groups
JYQ67_RS08595	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
JYQ67_RS08605	COG0463	Glycosyl transferase, family 2
JYQ67_RS08610	COG0628	permease
JYQ67_RS08615	COG0463	Glycosyl transferase, family 2
JYQ67_RS08625	COG0791	NLP P60 protein
JYQ67_RS08665	COG1705	Flagellar rod assembly protein muramidase FlgJ
JYQ67_RS08680	COG0562	UDP-galactopyranose mutase
JYQ67_RS08700	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JYQ67_RS08705	COG2137	regulation of response to DNA damage stimulus
JYQ67_RS08720	COG1295	ribonuclease BN
JYQ67_RS08725	COG1368	sulfuric ester hydrolase activity
JYQ67_RS08730	COG0024	Methionine aminopeptidase
JYQ67_RS08735	COG0716	FMN binding
JYQ67_RS08740	COG2246	polysaccharide biosynthetic process
JYQ67_RS08755	COG0513	Belongs to the DEAD box helicase family
JYQ67_RS08780	COG2918	glutathione biosynthetic process
JYQ67_RS08790	COG4841	protein insertion into membrane
JYQ67_RS08795	COG0488	(ABC) transporter
JYQ67_RS08805	COG2826	transposase and inactivated derivatives, IS30 family
JYQ67_RS08820	COG0783	Belongs to the Dps family
JYQ67_RS08830	COG1316	TRANSCRIPTIONal
JYQ67_RS08835	COG1846	Transcriptional regulator
JYQ67_RS08840	COG2223	nitrite transmembrane transporter activity
JYQ67_RS08850	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JYQ67_RS08865	COG2226	methyltransferase
JYQ67_RS08885	COG3760	aminoacyl-tRNA metabolism involved in translational fidelity
JYQ67_RS08895	COG1757	Na H antiporter
JYQ67_RS08920	COG2801	Transposase and inactivated derivatives
JYQ67_RS08970	COG2801	Transposase and inactivated derivatives
JYQ67_RS08980	COG3328	transposase activity
JYQ67_RS08990	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JYQ67_RS09020	COG0675	Transposase, IS605 OrfB family
JYQ67_RS09030	COG3328	transposase activity
JYQ67_RS09065	COG0732	type I restriction modification DNA specificity domain
JYQ67_RS09075	COG4974	Belongs to the 'phage' integrase family
JYQ67_RS09085	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
JYQ67_RS09125	COG2826	transposase and inactivated derivatives, IS30 family
JYQ67_RS09175	COG2801	Transposase and inactivated derivatives
JYQ67_RS09200	COG1802	Transcriptional regulator
JYQ67_RS09200	COG4626	Terminase
JYQ67_RS09205	COG4695	Portal protein
JYQ67_RS09210	COG0740	serine-type endopeptidase activity
JYQ67_RS09265	COG3328	transposase activity
JYQ67_RS09280	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JYQ67_RS09285	COG1597	lipid kinase activity
JYQ67_RS09290	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JYQ67_RS09295	COG0154	amidase activity
JYQ67_RS09300	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JYQ67_RS09305	COG4851	CamS sex pheromone cAM373 precursor
JYQ67_RS09310	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JYQ67_RS09325	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JYQ67_RS09330	COG1705	Flagellar rod assembly protein muramidase FlgJ
JYQ67_RS09345	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
JYQ67_RS09350	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JYQ67_RS09355	COG0101	tRNA pseudouridine synthase activity
JYQ67_RS09365	COG1122	ATPase activity
JYQ67_RS09370	COG1122	ATPase activity
JYQ67_RS09375	COG0203	ribosomal protein L17
JYQ67_RS09380	COG0202	RNA polymerase activity
JYQ67_RS09385	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JYQ67_RS09390	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JYQ67_RS09395	COG0257	Belongs to the bacterial ribosomal protein bL36 family
JYQ67_RS09400	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
JYQ67_RS09405	COG0563	adenylate kinase activity
JYQ67_RS09415	COG0200	Binds to the 23S rRNA
JYQ67_RS09420	COG1841	ribosomal large subunit assembly
JYQ67_RS09425	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JYQ67_RS09430	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
JYQ67_RS09435	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JYQ67_RS09440	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JYQ67_RS09445	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JYQ67_RS09450	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
JYQ67_RS09455	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
JYQ67_RS09460	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JYQ67_RS09470	COG0255	Belongs to the universal ribosomal protein uL29 family
JYQ67_RS09475	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
JYQ67_RS09480	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JYQ67_RS09485	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
JYQ67_RS09490	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JYQ67_RS09495	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JYQ67_RS09500	COG0089	rRNA binding
JYQ67_RS09505	COG0088	Forms part of the polypeptide exit tunnel
JYQ67_RS09510	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JYQ67_RS09515	COG0051	transcription antitermination factor activity, RNA binding
JYQ67_RS09520	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JYQ67_RS09525	COG0049	tRNA binding
JYQ67_RS09530	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
JYQ67_RS09545	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
JYQ67_RS09550	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JYQ67_RS09555	COG0085	RNA polymerase activity
JYQ67_RS09565	COG0542	response to heat
JYQ67_RS09570	COG4463	regulation of RNA biosynthetic process
JYQ67_RS09575	COG1064	alcohol dehydrogenase
JYQ67_RS09590	COG0110	maltose O-acetyltransferase activity
JYQ67_RS09610	COG0789	Transcriptional regulator
JYQ67_RS09625	COG1968	undecaprenyl-diphosphatase activity
JYQ67_RS09635	COG1028	Short-chain dehydrogenase reductase Sdr
JYQ67_RS09640	COG1028	Short-chain dehydrogenase reductase Sdr
JYQ67_RS09670	COG1428	Deoxynucleoside kinase
JYQ67_RS09675	COG0833	amino acid
JYQ67_RS09710	COG2826	transposase and inactivated derivatives, IS30 family
JYQ67_RS09715	COG1278	Cold shock
JYQ67_RS09770	COG2814	Major facilitator Superfamily
JYQ67_RS09785	COG0564	pseudouridine synthase activity
JYQ67_RS09795	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
JYQ67_RS09795	COG0392	lysyltransferase activity
JYQ67_RS09800	COG0693	protein deglycase activity
JYQ67_RS09805	COG0657	acetylesterase activity
JYQ67_RS09825	COG2267	carboxylic ester hydrolase activity
JYQ67_RS09845	COG3052	prosthetic group binding
JYQ67_RS09855	COG0281	malic enzyme
JYQ67_RS09865	COG0471	metal ion transport
JYQ67_RS09870	COG0039	L-malate dehydrogenase activity
JYQ67_RS09875	COG1053	succinate dehydrogenase
JYQ67_RS09880	COG0114	fumarate hydratase activity
JYQ67_RS09885	COG3976	FMN-binding domain protein
JYQ67_RS09885	COG0431	NADPH-dependent FMN reductase
JYQ67_RS09885	COG1053	succinate dehydrogenase
JYQ67_RS09890	COG3976	FMN-binding domain protein
JYQ67_RS09890	COG1053	succinate dehydrogenase
JYQ67_RS09890	COG0431	NADPH-dependent FMN reductase
JYQ67_RS09895	COG0281	malic enzyme
JYQ67_RS09900	COG0583	DNA-binding transcription factor activity
JYQ67_RS09915	COG0657	acetylesterase activity
JYQ67_RS09925	COG1263	PTS System
JYQ67_RS09925	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JYQ67_RS09925	COG2190	(PTS) system
JYQ67_RS09945	COG0583	DNA-binding transcription factor activity
JYQ67_RS09950	COG2326	polyphosphate kinase activity
JYQ67_RS09975	COG1686	Belongs to the peptidase S11 family
JYQ67_RS09985	COG2706	6-phosphogluconolactonase activity
JYQ67_RS10005	COG0494	nUDIX hydrolase
JYQ67_RS10035	COG1854	S-ribosylhomocysteine lyase activity
JYQ67_RS10040	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JYQ67_RS10055	COG1011	Hydrolase
JYQ67_RS10060	COG2502	aspartate--ammonia ligase
JYQ67_RS10075	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JYQ67_RS10085	COG0789	Transcriptional regulator
JYQ67_RS10090	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
JYQ67_RS10095	COG1984	allophanate hydrolase subunit 2
JYQ67_RS10105	COG0439	Biotin carboxylase
JYQ67_RS10110	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
JYQ67_RS10115	COG1914	H( )-stimulated, divalent metal cation uptake system
JYQ67_RS10130	COG3118	belongs to the thioredoxin family
JYQ67_RS10160	COG0531	amino acid
JYQ67_RS10170	COG0494	nUDIX hydrolase
JYQ67_RS10175	COG0110	maltose O-acetyltransferase activity
JYQ67_RS10180	COG0165	Argininosuccinate lyase
JYQ67_RS10200	COG0577	efflux transmembrane transporter activity
JYQ67_RS10200	COG1136	(ABC) transporter
JYQ67_RS10215	COG1136	(ABC) transporter
JYQ67_RS10215	COG0577	efflux transmembrane transporter activity
JYQ67_RS10225	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
JYQ67_RS10230	COG0393	Putative heavy-metal-binding
JYQ67_RS10240	COG2070	2-Nitropropane dioxygenase
JYQ67_RS10245	COG0640	Transcriptional regulator
JYQ67_RS10270	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JYQ67_RS10280	COG0519	Catalyzes the synthesis of GMP from XMP
JYQ67_RS10285	COG2357	RelA SpoT domain protein
JYQ67_RS10290	COG0745	RESPONSE REGULATOR receiver
JYQ67_RS10295	COG5002	protein histidine kinase activity
JYQ67_RS10300	COG1072	(Pantothenic acid kinase))
JYQ67_RS10310	COG1028	Short-chain dehydrogenase reductase Sdr
JYQ67_RS10315	COG1368	sulfuric ester hydrolase activity
JYQ67_RS10325	COG3973	AAA domain
JYQ67_RS10330	COG0586	Pfam SNARE associated Golgi protein
JYQ67_RS10340	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JYQ67_RS10345	COG4948	Mandelate Racemase Muconate Lactonizing
JYQ67_RS10355	COG0531	amino acid
JYQ67_RS10370	COG1511	domain protein
JYQ67_RS10380	COG2017	converts alpha-aldose to the beta-anomer
JYQ67_RS10395	COG0735	belongs to the Fur family
JYQ67_RS10400	COG0194	GDP metabolic process
JYQ67_RS10410	COG0531	amino acid
JYQ67_RS10415	COG2936	dipeptidyl-peptidase activity
JYQ67_RS10420	COG0675	Transposase, IS605 OrfB family
JYQ67_RS10430	COG2267	carboxylic ester hydrolase activity
JYQ67_RS10445	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JYQ67_RS10450	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JYQ67_RS10455	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JYQ67_RS10465	COG1376	ErfK ybiS ycfS ynhG family protein
JYQ67_RS10480	COG0488	(ABC) transporter
JYQ67_RS10490	COG4120	Belongs to the binding-protein-dependent transport system permease family
JYQ67_RS10495	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
JYQ67_RS10505	COG0004	ammonium transporteR
JYQ67_RS10510	COG0534	Mate efflux family protein
JYQ67_RS10515	COG1940	carbohydrate kinase activity
JYQ67_RS10525	COG1609	Transcriptional regulator
JYQ67_RS10530	COG2084	Dehydrogenase
JYQ67_RS10540	COG3118	belongs to the thioredoxin family
JYQ67_RS10545	COG0861	Integral membrane protein TerC family
JYQ67_RS10550	COG0564	pseudouridine synthase activity
JYQ67_RS10560	COG2233	PERMEase
JYQ67_RS10575	COG0702	epimerase
JYQ67_RS10580	COG0406	alpha-ribazole phosphatase activity
JYQ67_RS10585	COG1368	sulfuric ester hydrolase activity
JYQ67_RS10595	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JYQ67_RS10605	COG2217	Heavy metal translocating P-type atpase
JYQ67_RS10610	COG2217	Heavy metal translocating P-type atpase
JYQ67_RS10615	COG0492	ferredoxin-NADP+ reductase activity
JYQ67_RS10620	COG1957	nucleoside hydrolase
JYQ67_RS10630	COG1122	ATPase activity
JYQ67_RS10650	COG0095	Lipoate-protein ligase
JYQ67_RS10665	COG1396	sequence-specific DNA binding
JYQ67_RS10685	COG0589	response to stress
JYQ67_RS10710	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JYQ67_RS10715	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
JYQ67_RS10735	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
JYQ67_RS10740	COG1606	tRNA processing
JYQ67_RS10745	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JYQ67_RS10750	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
JYQ67_RS10770	COG3875	lactate racemase activity
JYQ67_RS10775	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JYQ67_RS10790	COG3328	transposase activity
JYQ67_RS10815	COG1869	D-ribose catabolic process
JYQ67_RS10825	COG2390	Transcriptional regulator
JYQ67_RS10830	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JYQ67_RS10840	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JYQ67_RS10845	COG3775	system Galactitol-specific IIC component
JYQ67_RS10850	COG1609	Transcriptional regulator
JYQ67_RS10875	COG0561	phosphatase activity
JYQ67_RS10880	COG2188	Transcriptional regulator
JYQ67_RS10885	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JYQ67_RS10915	COG1253	flavin adenine dinucleotide binding
JYQ67_RS10930	COG2807	transmembrane transport
JYQ67_RS10940	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
JYQ67_RS10945	COG0589	response to stress
JYQ67_RS10950	COG1522	sequence-specific DNA binding
JYQ67_RS10955	COG1028	Short-chain dehydrogenase reductase Sdr
JYQ67_RS10960	COG1609	Transcriptional regulator
JYQ67_RS10965	COG1164	Oligoendopeptidase f
JYQ67_RS10970	COG1301	dicarboxylic acid transport
JYQ67_RS10990	COG0277	FAD linked oxidase domain protein
JYQ67_RS11005	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JYQ67_RS11005	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JYQ67_RS11045	COG2826	transposase and inactivated derivatives, IS30 family
JYQ67_RS11090	COG2217	Heavy metal translocating P-type atpase
JYQ67_RS11110	COG0577	efflux transmembrane transporter activity
JYQ67_RS11140	COG1609	Transcriptional regulator
JYQ67_RS11145	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
JYQ67_RS11150	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JYQ67_RS11160	COG2365	Tyrosine phosphatase family
JYQ67_RS11165	COG1881	PFAM PEBP family protein
JYQ67_RS11175	COG1126	abc transporter atp-binding protein
JYQ67_RS11180	COG0765	amino acid transport
JYQ67_RS11185	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JYQ67_RS11195	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JYQ67_RS11200	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JYQ67_RS11210	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
JYQ67_RS11215	COG3590	peptidase
JYQ67_RS11220	COG2252	PERMEase
JYQ67_RS11240	COG2094	Belongs to the DNA glycosylase MPG family
JYQ67_RS11245	COG3189	MarR family transcriptional regulator
JYQ67_RS11255	COG2249	NAD(P)H dehydrogenase (quinone) activity
JYQ67_RS11265	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
JYQ67_RS11270	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JYQ67_RS11285	COG1609	Transcriptional regulator
JYQ67_RS11290	COG1705	Flagellar rod assembly protein muramidase FlgJ
JYQ67_RS11290	COG1388	LysM domain
JYQ67_RS11295	COG0640	Transcriptional regulator
JYQ67_RS11300	COG0675	Transposase, IS605 OrfB family
JYQ67_RS11355	COG3328	transposase activity
JYQ67_RS11365	COG1914	H( )-stimulated, divalent metal cation uptake system
JYQ67_RS11375	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JYQ67_RS11400	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JYQ67_RS11405	COG0367	asparagine synthase
JYQ67_RS11410	COG0833	amino acid
JYQ67_RS11415	COG1970	mechanosensitive ion channel activity
JYQ67_RS11420	COG0445	tRNA wobble uridine modification
JYQ67_RS11425	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JYQ67_RS11435	COG0706	membrane insertase activity
JYQ67_RS11440	COG0594	ribonuclease P activity
JYQ67_RS11445	COG0230	Belongs to the bacterial ribosomal protein bL34 family