locus-tag	class	description
JYQ65_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JYQ65_RS00010	COG0592	DNA-directed DNA polymerase activity
JYQ65_RS00015	COG2501	S4 domain
JYQ65_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JYQ65_RS00025	COG0187	DNA topoisomerase II activity
JYQ65_RS00045	COG0360	Binds together with S18 to 16S ribosomal RNA
JYQ65_RS00050	COG0629	single-stranded DNA binding
JYQ65_RS00055	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JYQ65_RS00065	COG0359	binds to the 23S rRNA
JYQ65_RS00070	COG0305	Participates in initiation and elongation during chromosome replication
JYQ65_RS00090	COG2826	transposase and inactivated derivatives, IS30 family
JYQ65_RS00105	COG0745	RESPONSE REGULATOR receiver
JYQ65_RS00125	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
JYQ65_RS00130	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JYQ65_RS00135	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
JYQ65_RS00140	COG1959	2 iron, 2 sulfur cluster binding
JYQ65_RS00145	COG1609	Transcriptional regulator
JYQ65_RS00155	COG1554	hydrolase, family 65, central catalytic
JYQ65_RS00160	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JYQ65_RS00165	COG1131	(ABC) transporter
JYQ65_RS00185	COG0436	Aminotransferase
JYQ65_RS00205	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
JYQ65_RS00210	COG1074	ATP-dependent DNA helicase activity
JYQ65_RS00215	COG0656	L-ascorbic acid biosynthetic process
JYQ65_RS00265	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JYQ65_RS00270	COG1012	belongs to the aldehyde dehydrogenase family
JYQ65_RS00275	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JYQ65_RS00280	COG0284	orotidine-5'-phosphate decarboxylase activity
JYQ65_RS00285	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JYQ65_RS00300	COG0438	transferase activity, transferring glycosyl groups
JYQ65_RS00330	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JYQ65_RS00335	COG1114	Component of the transport system for branched-chain amino acids
JYQ65_RS00340	COG0667	Aldo Keto reductase
JYQ65_RS00345	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
JYQ65_RS00355	COG1696	Membrane protein involved in D-alanine export
JYQ65_RS00360	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JYQ65_RS00370	COG0420	3'-5' exonuclease activity
JYQ65_RS00375	COG0419	ATPase involved in DNA repair
JYQ65_RS00380	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JYQ65_RS00395	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JYQ65_RS00400	COG0765	amino acid transport
JYQ65_RS00410	COG1113	amino acid transport
JYQ65_RS00415	COG2826	transposase and inactivated derivatives, IS30 family
JYQ65_RS00430	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JYQ65_RS00440	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JYQ65_RS00450	COG0357	Ribosomal RNA small subunit methyltransferase G
JYQ65_RS00460	COG1475	DNA binding
JYQ65_RS00465	COG4481	Protein conserved in bacteria
JYQ65_RS00470	COG0012	GTP binding
JYQ65_RS00480	COG0516	GMP reductase activity
JYQ65_RS00480	COG0517	IMP dehydrogenase activity
JYQ65_RS00495	COG0489	protein tyrosine kinase activity
JYQ65_RS00500	COG4464	protein tyrosine phosphatase activity
JYQ65_RS00515	COG1216	Glycosyl transferase, family 2
JYQ65_RS00525	COG1216	Glycosyl transferase, family 2
JYQ65_RS00535	COG0438	transferase activity, transferring glycosyl groups
JYQ65_RS00540	COG0728	peptidoglycan biosynthetic process
JYQ65_RS00550	COG3328	transposase activity
JYQ65_RS00555	COG0438	transferase activity, transferring glycosyl groups
JYQ65_RS00580	COG0438	transferase activity, transferring glycosyl groups
JYQ65_RS00600	COG2801	Transposase and inactivated derivatives
JYQ65_RS00615	COG2801	Transposase and inactivated derivatives
JYQ65_RS00635	COG3328	transposase activity
JYQ65_RS00650	COG0745	RESPONSE REGULATOR receiver
JYQ65_RS00660	COG1686	Belongs to the peptidase S11 family
JYQ65_RS00680	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JYQ65_RS00685	COG0675	Transposase, IS605 OrfB family
JYQ65_RS00695	COG3328	transposase activity
JYQ65_RS00710	COG0628	permease
JYQ65_RS00715	COG2759	Belongs to the formate--tetrahydrofolate ligase family
JYQ65_RS00720	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JYQ65_RS00725	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
JYQ65_RS00730	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JYQ65_RS00745	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
JYQ65_RS00750	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JYQ65_RS00755	COG0047	phosphoribosylformylglycinamidine synthase activity
JYQ65_RS00760	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JYQ65_RS00770	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
JYQ65_RS00775	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JYQ65_RS00780	COG0138	bifunctional purine biosynthesis protein purh
JYQ65_RS00785	COG0151	Belongs to the GarS family
JYQ65_RS00790	COG0588	phosphoglycerate mutase activity
JYQ65_RS00795	COG0436	Aminotransferase
JYQ65_RS00875	COG1609	Transcriptional regulator
JYQ65_RS00895	COG1942	4-Oxalocrotonate Tautomerase
JYQ65_RS00915	COG4221	oxidoreductase activity
JYQ65_RS00930	COG0667	Aldo Keto reductase
JYQ65_RS00940	COG0675	Transposase, IS605 OrfB family
JYQ65_RS00950	COG0697	spore germination
JYQ65_RS00985	COG1120	ATPase activity
JYQ65_RS00990	COG0477	Major facilitator Superfamily
JYQ65_RS01005	COG0708	Exodeoxyribonuclease III
JYQ65_RS01035	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
JYQ65_RS01045	COG2508	Transcriptional regulator
JYQ65_RS01065	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
JYQ65_RS01095	COG1063	alcohol dehydrogenase
JYQ65_RS01115	COG0583	DNA-binding transcription factor activity
JYQ65_RS01125	COG0778	Nitroreductase
JYQ65_RS01145	COG3973	AAA domain
JYQ65_RS01150	COG0248	Ppx GppA phosphatase
JYQ65_RS01165	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
JYQ65_RS01175	COG1801	Protein of unknown function DUF72
JYQ65_RS01180	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JYQ65_RS01180	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JYQ65_RS01185	COG0084	hydrolase, TatD family'
JYQ65_RS01190	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
JYQ65_RS01195	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
JYQ65_RS01200	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
JYQ65_RS01210	COG1121	(ABC) transporter
JYQ65_RS01215	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JYQ65_RS01220	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JYQ65_RS01225	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JYQ65_RS01230	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JYQ65_RS01245	COG1078	dGTPase activity
JYQ65_RS01255	COG3343	RNA polymerase activity
JYQ65_RS01260	COG0504	CTP synthase activity
JYQ65_RS01265	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JYQ65_RS01270	COG0254	rRNA binding
JYQ65_RS01280	COG3764	Sortase (surface protein transpeptidase)
JYQ65_RS01295	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JYQ65_RS01300	COG1704	LemA family
JYQ65_RS01305	COG0501	Belongs to the peptidase M48B family
JYQ65_RS01310	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JYQ65_RS01320	COG0736	holo-[acyl-carrier-protein] synthase activity
JYQ65_RS01325	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JYQ65_RS01330	COG2337	Toxic component of a toxin-antitoxin (TA) module
JYQ65_RS01340	COG0193	aminoacyl-tRNA hydrolase activity
JYQ65_RS01345	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JYQ65_RS01350	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
JYQ65_RS01360	COG1098	S1 RNA binding domain
JYQ65_RS01365	COG0037	tRNA processing
JYQ65_RS01380	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
JYQ65_RS01385	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JYQ65_RS01390	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
JYQ65_RS01440	COG3328	transposase activity
JYQ65_RS01480	COG3104	oligopeptide transport
JYQ65_RS01505	COG1794	racemase activity, acting on amino acids and derivatives
JYQ65_RS01510	COG2188	Transcriptional regulator
JYQ65_RS01515	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JYQ65_RS01520	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
JYQ65_RS01525	COG2183	response to ionizing radiation
JYQ65_RS01530	COG3091	SprT-like family
JYQ65_RS01540	COG3250	beta-galactosidase activity
JYQ65_RS01545	COG3250	beta-galactosidase activity
JYQ65_RS01555	COG0588	phosphoglycerate mutase activity
JYQ65_RS01560	COG0657	acetylesterase activity
JYQ65_RS01570	COG0110	maltose O-acetyltransferase activity
JYQ65_RS01595	COG0756	dUTP diphosphatase activity
JYQ65_RS01600	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JYQ65_RS01605	COG4956	integral membrane protein (PIN domain superfamily)
JYQ65_RS01610	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JYQ65_RS01620	COG0215	cysteine-tRNA ligase activity
JYQ65_RS01625	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
JYQ65_RS01630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JYQ65_RS01640	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JYQ65_RS01650	COG0250	Participates in transcription elongation, termination and antitermination
JYQ65_RS01655	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
JYQ65_RS01660	COG0081	regulation of translation
JYQ65_RS01665	COG2826	transposase and inactivated derivatives, IS30 family
JYQ65_RS01670	COG0531	amino acid
JYQ65_RS01675	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JYQ65_RS01680	COG0222	ribosome binding
JYQ65_RS01685	COG1271	oxidase subunit
JYQ65_RS01690	COG1294	oxidase, subunit
JYQ65_RS01695	COG4988	ABC transporter
JYQ65_RS01700	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
JYQ65_RS01705	COG1012	belongs to the aldehyde dehydrogenase family
JYQ65_RS01705	COG1454	alcohol dehydrogenase
JYQ65_RS01710	COG1114	Component of the transport system for branched-chain amino acids
JYQ65_RS01715	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JYQ65_RS01720	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JYQ65_RS01725	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
JYQ65_RS01730	COG0590	tRNA wobble adenosine to inosine editing
JYQ65_RS01740	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JYQ65_RS01745	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JYQ65_RS01750	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JYQ65_RS01760	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JYQ65_RS01765	COG3870	Protein conserved in bacteria
JYQ65_RS01770	COG0470	DNA polymerase III
JYQ65_RS01775	COG4467	Involved in initiation control of chromosome replication
JYQ65_RS01795	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
JYQ65_RS01800	COG0248	Ppx GppA phosphatase
JYQ65_RS01805	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JYQ65_RS01815	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JYQ65_RS01825	COG2235	arginine
JYQ65_RS01835	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JYQ65_RS01840	COG0436	Aminotransferase
JYQ65_RS01845	COG2826	transposase and inactivated derivatives, IS30 family
JYQ65_RS01850	COG1214	PFAM Peptidase M22, glycoprotease
JYQ65_RS01860	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JYQ65_RS01875	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JYQ65_RS01885	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JYQ65_RS01895	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
JYQ65_RS01900	COG1028	Short-chain dehydrogenase reductase Sdr
JYQ65_RS01905	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JYQ65_RS01910	COG0511	ligase activity, forming carbon-carbon bonds
JYQ65_RS01920	COG0439	Biotin carboxylase
JYQ65_RS01925	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
JYQ65_RS01930	COG0825	malonyl-CoA metabolic process
JYQ65_RS01935	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
JYQ65_RS01940	COG1268	BioY protein
JYQ65_RS01950	COG0488	(ABC) transporter
JYQ65_RS01955	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
JYQ65_RS01960	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
JYQ65_RS01965	COG0459	protein refolding
JYQ65_RS01970	COG0531	amino acid
JYQ65_RS01985	COG1739	Uncharacterized protein family UPF0029
JYQ65_RS01990	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
JYQ65_RS02005	COG0653	protein targeting
JYQ65_RS02020	COG1950	PFAM Membrane protein of
JYQ65_RS02025	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
JYQ65_RS02030	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JYQ65_RS02035	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
JYQ65_RS02045	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JYQ65_RS02050	COG0436	Aminotransferase
JYQ65_RS02055	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JYQ65_RS02065	COG0675	Transposase, IS605 OrfB family
JYQ65_RS02080	COG2801	Transposase and inactivated derivatives
JYQ65_RS02085	COG0492	ferredoxin-NADP+ reductase activity
JYQ65_RS02090	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
JYQ65_RS02095	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JYQ65_RS02100	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JYQ65_RS02110	COG0561	phosphatase activity
JYQ65_RS02120	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JYQ65_RS02135	COG0556	nucleotide-excision repair
JYQ65_RS02140	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JYQ65_RS02150	COG1660	Displays ATPase and GTPase activities
JYQ65_RS02155	COG0391	Required for morphogenesis under gluconeogenic growth conditions
JYQ65_RS02160	COG1481	regulation of sporulation
JYQ65_RS02170	COG0740	serine-type endopeptidase activity
JYQ65_RS02240	COG2801	Transposase and inactivated derivatives
JYQ65_RS02260	COG0126	phosphoglycerate kinase activity
JYQ65_RS02265	COG0149	triose-phosphate isomerase activity
JYQ65_RS02270	COG0148	phosphopyruvate hydratase activity
JYQ65_RS02275	COG1113	amino acid transport
JYQ65_RS02290	COG0557	exoribonuclease II activity
JYQ65_RS02295	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
JYQ65_RS02305	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
JYQ65_RS02310	COG0280	phosphate acetyltransferase
JYQ65_RS02315	COG0802	atpase or kinase
JYQ65_RS02325	COG2176	DNA-directed DNA polymerase activity
JYQ65_RS02330	COG0812	UDP-N-acetylmuramate dehydrogenase activity
JYQ65_RS02345	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JYQ65_RS02350	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JYQ65_RS02360	COG2755	lipolytic protein G-D-S-L family
JYQ65_RS02360	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
JYQ65_RS02365	COG0561	phosphatase activity
JYQ65_RS02370	COG3942	CHAP domain
JYQ65_RS02370	COG1388	LysM domain
JYQ65_RS02375	COG2855	membrane
JYQ65_RS02380	COG0583	DNA-binding transcription factor activity
JYQ65_RS02385	COG1482	cell wall glycoprotein biosynthetic process
JYQ65_RS02390	COG1307	EDD domain protein, DegV family
JYQ65_RS02410	COG3715	PTS system
JYQ65_RS02415	COG3716	PTS system mannose fructose sorbose family IID component
JYQ65_RS02430	COG0745	RESPONSE REGULATOR receiver
JYQ65_RS02435	COG5002	protein histidine kinase activity
JYQ65_RS02435	COG3850	Histidine kinase
JYQ65_RS02440	COG4975	Glucose uptake
JYQ65_RS02450	COG2801	Transposase and inactivated derivatives
JYQ65_RS02460	COG0675	Transposase, IS605 OrfB family
JYQ65_RS02465	COG0450	alkyl hydroperoxide reductase
JYQ65_RS02495	COG0656	L-ascorbic acid biosynthetic process
JYQ65_RS02500	COG0149	triose-phosphate isomerase activity
JYQ65_RS02505	COG3527	Alpha-acetolactate decarboxylase
JYQ65_RS02540	COG1132	(ABC) transporter
JYQ65_RS02545	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JYQ65_RS02560	COG3442	glutamine amidotransferase
JYQ65_RS02565	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JYQ65_RS02570	COG1435	thymidine kinase activity
JYQ65_RS02575	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JYQ65_RS02580	COG2890	protein-(glutamine-N5) methyltransferase activity
JYQ65_RS02585	COG0009	L-threonylcarbamoyladenylate synthase
JYQ65_RS02590	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JYQ65_RS02595	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JYQ65_RS02615	COG2233	PERMEase
JYQ65_RS02620	COG0356	it plays a direct role in the translocation of protons across the membrane
JYQ65_RS02625	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JYQ65_RS02630	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JYQ65_RS02635	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JYQ65_RS02640	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JYQ65_RS02645	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JYQ65_RS02650	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JYQ65_RS02655	COG0355	proton-transporting ATP synthase activity, rotational mechanism
JYQ65_RS02665	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JYQ65_RS02670	COG1077	Cell shape determining protein MreB Mrl
JYQ65_RS02675	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
JYQ65_RS02685	COG0772	Belongs to the SEDS family
JYQ65_RS02700	COG1181	Belongs to the D-alanine--D-alanine ligase family
JYQ65_RS02710	COG0589	response to stress
JYQ65_RS02720	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JYQ65_RS02740	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JYQ65_RS02755	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JYQ65_RS02760	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
JYQ65_RS02765	COG1104	cysteine desulfurase activity
JYQ65_RS02770	COG0301	tRNA thio-modification
JYQ65_RS02775	COG2610	gluconate transmembrane transporter activity
JYQ65_RS02780	COG1929	Belongs to the glycerate kinase type-1 family
JYQ65_RS02815	COG0675	Transposase, IS605 OrfB family
JYQ65_RS02830	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
JYQ65_RS02835	COG0525	valine-tRNA ligase activity
JYQ65_RS02840	COG0285	dihydrofolate synthase activity
JYQ65_RS02855	COG1077	Cell shape determining protein MreB Mrl
JYQ65_RS02860	COG1792	Involved in formation and maintenance of cell shape
JYQ65_RS02870	COG0765	amino acid transport
JYQ65_RS02875	COG1126	abc transporter atp-binding protein
JYQ65_RS02880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JYQ65_RS02885	COG0612	Peptidase, M16
JYQ65_RS02890	COG0612	Peptidase, M16
JYQ65_RS02895	COG1426	Protein conserved in bacteria
JYQ65_RS02900	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JYQ65_RS02905	COG1058	Belongs to the CinA family
JYQ65_RS02905	COG1546	Belongs to the CinA family
JYQ65_RS02910	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JYQ65_RS02920	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JYQ65_RS02925	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JYQ65_RS02930	COG0632	four-way junction helicase activity
JYQ65_RS02935	COG2255	four-way junction helicase activity
JYQ65_RS02950	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
JYQ65_RS02955	COG0513	Belongs to the DEAD box helicase family
JYQ65_RS02960	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JYQ65_RS02965	COG4472	Bacterial protein of unknown function (DUF965)
JYQ65_RS02970	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JYQ65_RS02975	COG3906	Belongs to the UPF0473 family
JYQ65_RS02980	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JYQ65_RS02990	COG1193	negative regulation of DNA recombination
JYQ65_RS02995	COG3118	belongs to the thioredoxin family
JYQ65_RS03010	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
JYQ65_RS03015	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JYQ65_RS03020	COG0622	Phosphoesterase
JYQ65_RS03025	COG0561	phosphatase activity
JYQ65_RS03030	COG0668	transmembrane transport
JYQ65_RS03045	COG0006	proline dipeptidase activity
JYQ65_RS03050	COG1609	Transcriptional regulator
JYQ65_RS03060	COG0217	transcriptional regulatory protein
JYQ65_RS03065	COG1388	LysM domain
JYQ65_RS03065	COG0791	NLP P60 protein
JYQ65_RS03075	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JYQ65_RS03085	COG4537	Required for transformation and DNA binding
JYQ65_RS03105	COG0827	DNA restriction-modification system
JYQ65_RS03110	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JYQ65_RS03120	COG4470	Protein conserved in bacteria
JYQ65_RS03125	COG0647	UMP catabolic process
JYQ65_RS03135	COG0586	Pfam SNARE associated Golgi protein
JYQ65_RS03255	COG1393	Belongs to the ArsC family
JYQ65_RS03260	COG4862	establishment of competence for transformation
JYQ65_RS03275	COG2357	RelA SpoT domain protein
JYQ65_RS03280	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JYQ65_RS03285	COG0564	pseudouridine synthase activity
JYQ65_RS03290	COG2706	6-phosphogluconolactonase activity
JYQ65_RS03295	COG0500	methyltransferase
JYQ65_RS03305	COG1674	ftsk spoiiie
JYQ65_RS03320	COG2001	Belongs to the MraZ family
JYQ65_RS03325	COG0275	rRNA processing
JYQ65_RS03335	COG0768	penicillin binding
JYQ65_RS03340	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JYQ65_RS03345	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JYQ65_RS03350	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JYQ65_RS03360	COG0849	cell division
JYQ65_RS03365	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JYQ65_RS03370	COG1799	cell septum assembly
JYQ65_RS03385	COG3599	regulation of cell shape
JYQ65_RS03390	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JYQ65_RS03395	COG1278	Cold shock
JYQ65_RS03410	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JYQ65_RS03420	COG0482	sulfurtransferase activity
JYQ65_RS03435	COG0406	alpha-ribazole phosphatase activity
JYQ65_RS03445	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
JYQ65_RS03450	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JYQ65_RS03455	COG1393	Belongs to the ArsC family
JYQ65_RS03460	COG1597	lipid kinase activity
JYQ65_RS03465	COG5503	Protein of unknown function (DUF1447)
JYQ65_RS03475	COG0242	peptide deformylase activity
JYQ65_RS03480	COG4476	Belongs to the UPF0223 family
JYQ65_RS03485	COG0483	inositol monophosphate 1-phosphatase activity
JYQ65_RS03490	COG1217	gtp-binding protein TYPA
JYQ65_RS03500	COG4471	UPF0298 protein
JYQ65_RS03505	COG0742	ribosomal rna small subunit methyltransferase
JYQ65_RS03510	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JYQ65_RS03515	COG3480	Lon protease (S16) C-terminal proteolytic domain
JYQ65_RS03520	COG1596	polysaccharide export
JYQ65_RS03520	COG1555	photosystem II stabilization
JYQ65_RS03525	COG2131	deaminase
JYQ65_RS03530	COG2333	competence protein COMEC
JYQ65_RS03530	COG0658	competence protein
JYQ65_RS03535	COG1466	dna polymerase III delta subunit
JYQ65_RS03540	COG0268	Binds directly to 16S ribosomal RNA
JYQ65_RS03545	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
JYQ65_RS03575	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JYQ65_RS03580	COG0544	peptidyl-prolyl cis-trans isomerase activity
JYQ65_RS03585	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JYQ65_RS03590	COG0218	Necessary for normal cell division and for the maintenance of normal septation
JYQ65_RS03605	COG1126	abc transporter atp-binding protein
JYQ65_RS03610	COG0322	excinuclease ABC activity
JYQ65_RS03615	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JYQ65_RS03620	COG1234	tRNA 3'-trailer cleavage
JYQ65_RS03625	COG0300	oxidoreductase activity
JYQ65_RS03630	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
JYQ65_RS03630	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
JYQ65_RS03635	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JYQ65_RS03645	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JYQ65_RS03660	COG2249	NAD(P)H dehydrogenase (quinone) activity
JYQ65_RS03680	COG1396	sequence-specific DNA binding
JYQ65_RS03695	COG1028	Short-chain dehydrogenase reductase Sdr
JYQ65_RS03715	COG2814	Major facilitator Superfamily
JYQ65_RS03725	COG0367	asparagine synthase
JYQ65_RS03825	COG1393	Belongs to the ArsC family
JYQ65_RS03880	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JYQ65_RS03915	COG4152	abc transporter atp-binding protein
JYQ65_RS03950	COG2801	Transposase and inactivated derivatives
JYQ65_RS04020	COG2217	Heavy metal translocating P-type atpase
JYQ65_RS04045	COG2814	Major facilitator Superfamily
JYQ65_RS04065	COG0446	pyridine nucleotide-disulphide oxidoreductase
JYQ65_RS04160	COG1396	sequence-specific DNA binding
JYQ65_RS04170	COG3645	SOS response
JYQ65_RS04170	COG3646	Phage regulatory protein
JYQ65_RS04215	COG0629	single-stranded DNA binding
JYQ65_RS04285	COG2801	Transposase and inactivated derivatives
JYQ65_RS04305	COG1196	nuclear chromosome segregation
JYQ65_RS04320	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
JYQ65_RS04325	COG2826	transposase and inactivated derivatives, IS30 family
JYQ65_RS04335	COG2826	transposase and inactivated derivatives, IS30 family
JYQ65_RS04345	COG3328	transposase activity
JYQ65_RS04370	COG1556	Lactate utilization protein
JYQ65_RS04375	COG1139	Iron-sulfur cluster binding protein
JYQ65_RS04380	COG0247	lactate metabolic process
JYQ65_RS04385	COG3425	synthase
JYQ65_RS04390	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JYQ65_RS04395	COG4224	UPF0291 protein
JYQ65_RS04400	COG3763	UPF0154 protein
JYQ65_RS04405	COG0204	Acyl-transferase
JYQ65_RS04410	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
JYQ65_RS04415	COG2827	Endonuclease containing a URI domain
JYQ65_RS04420	COG0052	Belongs to the universal ribosomal protein uS2 family
JYQ65_RS04425	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JYQ65_RS04435	COG0233	cytoplasmic translational termination
JYQ65_RS04440	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JYQ65_RS04445	COG4589	Belongs to the CDS family
JYQ65_RS04450	COG0750	zinc metalloprotease
JYQ65_RS04455	COG0442	prolyl-tRNA aminoacylation
JYQ65_RS04460	COG2176	DNA-directed DNA polymerase activity
JYQ65_RS04465	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JYQ65_RS04470	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
JYQ65_RS04475	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
JYQ65_RS04480	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
JYQ65_RS04485	COG0505	Belongs to the CarA family
JYQ65_RS04490	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JYQ65_RS04495	COG0779	Required for maturation of 30S ribosomal subunits
JYQ65_RS04500	COG0195	Participates in both transcription termination and antitermination
JYQ65_RS04505	COG2740	Nucleic-acid-binding protein implicated in transcription termination
JYQ65_RS04515	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JYQ65_RS04520	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JYQ65_RS04525	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JYQ65_RS04530	COG0196	riboflavin kinase activity
JYQ65_RS04535	COG2814	Major facilitator Superfamily
JYQ65_RS04560	COG3328	transposase activity
JYQ65_RS04565	COG2801	Transposase and inactivated derivatives
JYQ65_RS04590	COG1609	Transcriptional regulator
JYQ65_RS04595	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JYQ65_RS04635	COG3759	membrane
JYQ65_RS04660	COG2801	Transposase and inactivated derivatives
JYQ65_RS04670	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JYQ65_RS04695	COG1420	regulation of RNA biosynthetic process
JYQ65_RS04700	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JYQ65_RS04705	COG0443	Heat shock 70 kDa protein
JYQ65_RS04710	COG0484	heat shock protein binding
JYQ65_RS04725	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
JYQ65_RS04730	COG0140	phosphoribosyl-ATP diphosphatase activity
JYQ65_RS04735	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JYQ65_RS04740	COG0481	GTPase activity
JYQ65_RS04750	COG0406	alpha-ribazole phosphatase activity
JYQ65_RS04755	COG0667	Aldo Keto reductase
JYQ65_RS04760	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
JYQ65_RS04765	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JYQ65_RS04780	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
JYQ65_RS04790	COG0307	riboflavin synthase, alpha
JYQ65_RS04795	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JYQ65_RS04795	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JYQ65_RS04805	COG5002	protein histidine kinase activity
JYQ65_RS04810	COG0745	RESPONSE REGULATOR receiver
JYQ65_RS04820	COG1104	cysteine desulfurase activity
JYQ65_RS04840	COG1811	Na channel or pump
JYQ65_RS04845	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JYQ65_RS04855	COG1464	Belongs to the NlpA lipoprotein family
JYQ65_RS04860	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JYQ65_RS04875	COG0351	phosphomethylpyrimidine kinase
JYQ65_RS04880	COG0352	thiamine-phosphate diphosphorylase activity
JYQ65_RS04885	COG0351	phosphomethylpyrimidine kinase
JYQ65_RS04890	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
JYQ65_RS04905	COG1518	maintenance of DNA repeat elements
JYQ65_RS04925	COG0657	acetylesterase activity
JYQ65_RS04955	COG0039	L-malate dehydrogenase activity
JYQ65_RS04965	COG2264	protein methyltransferase activity
JYQ65_RS04970	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JYQ65_RS04980	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JYQ65_RS04985	COG1490	D-aminoacyl-tRNA deacylase activity
JYQ65_RS04995	COG0626	cystathionine gamma-synthase activity
JYQ65_RS05000	COG0626	cystathionine gamma-synthase activity
JYQ65_RS05005	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JYQ65_RS05010	COG0456	acetyltransferase
JYQ65_RS05015	COG0765	amino acid transport
JYQ65_RS05020	COG1126	abc transporter atp-binding protein
JYQ65_RS05025	COG1473	amidohydrolase
JYQ65_RS05030	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JYQ65_RS05035	COG2079	MmgE PrpD family protein
JYQ65_RS05040	COG0765	amino acid transport
JYQ65_RS05045	COG0765	amino acid transport
JYQ65_RS05050	COG1126	abc transporter atp-binding protein
JYQ65_RS05065	COG0460	homoserine dehydrogenase
JYQ65_RS05070	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
JYQ65_RS05075	COG0833	amino acid
JYQ65_RS05080	COG2040	homocysteine
JYQ65_RS05085	COG3001	Fructosamine kinase
JYQ65_RS05090	COG0860	N-Acetylmuramoyl-L-alanine amidase
JYQ65_RS05100	COG0124	histidyl-tRNA synthetase
JYQ65_RS05105	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
JYQ65_RS05115	COG0828	Belongs to the bacterial ribosomal protein bS21 family
JYQ65_RS05120	COG1610	YqeY-like protein
JYQ65_RS05125	COG1702	phosphate starvation-inducible protein PhoH
JYQ65_RS05130	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JYQ65_RS05135	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
JYQ65_RS05140	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JYQ65_RS05145	COG1381	Involved in DNA repair and RecF pathway recombination
JYQ65_RS05150	COG0752	glycyl-tRNA synthetase alpha subunit
JYQ65_RS05155	COG0751	glycine-tRNA ligase activity
JYQ65_RS05160	COG0358	DNA primase activity
JYQ65_RS05165	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JYQ65_RS05180	COG2801	Transposase and inactivated derivatives
JYQ65_RS05205	COG2261	transglycosylase associated protein
JYQ65_RS05215	COG2826	transposase and inactivated derivatives, IS30 family
JYQ65_RS05235	COG0527	aspartate kinase activity
JYQ65_RS05240	COG0019	diaminopimelate decarboxylase activity
JYQ65_RS05245	COG2171	N-acyltransferase activity
JYQ65_RS05250	COG1473	amidohydrolase
JYQ65_RS05255	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JYQ65_RS05260	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JYQ65_RS05265	COG0436	Aminotransferase
JYQ65_RS05270	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JYQ65_RS05275	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JYQ65_RS05280	COG0569	domain protein
JYQ65_RS05285	COG2384	SAM-dependent methyltransferase
JYQ65_RS05290	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JYQ65_RS05295	COG2195	Cleaves the N-terminal amino acid of tripeptides
JYQ65_RS05305	COG0587	DNA-directed DNA polymerase activity
JYQ65_RS05330	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
JYQ65_RS05335	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JYQ65_RS05340	COG1187	pseudouridine synthase activity
JYQ65_RS05345	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
JYQ65_RS05355	COG0514	ATP-dependent DNA helicase (RecQ)
JYQ65_RS05365	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
JYQ65_RS05370	COG0539	negative regulation of cytoplasmic translation
JYQ65_RS05375	COG1160	GTP binding
JYQ65_RS05385	COG0457	Tetratricopeptide repeat
JYQ65_RS05395	COG0617	tRNA 3'-terminal CCA addition
JYQ65_RS05400	COG0488	(ABC) transporter
JYQ65_RS05405	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
JYQ65_RS05410	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JYQ65_RS05415	COG1272	protein, Hemolysin III
JYQ65_RS05420	COG1307	EDD domain protein, DegV family
JYQ65_RS05425	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JYQ65_RS05435	COG2755	lipolytic protein G-D-S-L family
JYQ65_RS05440	COG4698	Protein conserved in bacteria
JYQ65_RS05445	COG4479	Belongs to the UPF0346 family
JYQ65_RS05450	COG3328	transposase activity
JYQ65_RS05520	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JYQ65_RS05525	COG0758	DNA mediated transformation
JYQ65_RS05530	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JYQ65_RS05545	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
JYQ65_RS05550	COG0187	DNA topoisomerase II activity
JYQ65_RS05555	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JYQ65_RS05575	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JYQ65_RS05585	COG1956	GAF domain-containing protein
JYQ65_RS05595	COG0402	S-adenosylhomocysteine deaminase activity
JYQ65_RS05610	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JYQ65_RS05615	COG1811	Na channel or pump
JYQ65_RS05620	COG2223	nitrite transmembrane transporter activity
JYQ65_RS05635	COG2814	Major facilitator Superfamily
JYQ65_RS05660	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JYQ65_RS05665	COG0110	maltose O-acetyltransferase activity
JYQ65_RS05670	COG0110	maltose O-acetyltransferase activity
JYQ65_RS05690	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JYQ65_RS05700	COG2423	ornithine cyclodeaminase activity
JYQ65_RS05745	COG0656	L-ascorbic acid biosynthetic process
JYQ65_RS05750	COG4720	Psort location CytoplasmicMembrane, score
JYQ65_RS05760	COG0538	isocitrate dehydrogenase activity
JYQ65_RS05770	COG4974	Belongs to the 'phage' integrase family
JYQ65_RS05775	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
JYQ65_RS05780	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
JYQ65_RS05795	COG1063	alcohol dehydrogenase
JYQ65_RS05820	COG1732	Glycine betaine
JYQ65_RS05850	COG3328	transposase activity
JYQ65_RS05855	COG2814	Major facilitator Superfamily
JYQ65_RS05890	COG4975	Glucose uptake
JYQ65_RS05900	COG4975	Glucose uptake
JYQ65_RS05905	COG1609	Transcriptional regulator
JYQ65_RS05910	COG2801	Transposase and inactivated derivatives
JYQ65_RS05995	COG0318	PFAM AMP-dependent synthetase and ligase
JYQ65_RS06000	COG2271	Major facilitator Superfamily
JYQ65_RS06010	COG0626	cystathionine gamma-synthase activity
JYQ65_RS06015	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JYQ65_RS06025	COG2848	UPF0210 protein
JYQ65_RS06050	COG2826	transposase and inactivated derivatives, IS30 family
JYQ65_RS06065	COG0697	spore germination
JYQ65_RS06075	COG3976	FMN-binding domain protein
JYQ65_RS06075	COG1053	succinate dehydrogenase
JYQ65_RS06080	COG0583	DNA-binding transcription factor activity
JYQ65_RS06090	COG0183	Belongs to the thiolase family
JYQ65_RS06095	COG0628	permease
JYQ65_RS06100	COG0730	response to heat
JYQ65_RS06105	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
JYQ65_RS06110	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JYQ65_RS06135	COG1250	3-hydroxyacyl-CoA dehydrogenase
JYQ65_RS06145	COG4690	dipeptidase activity
JYQ65_RS06155	COG2826	transposase and inactivated derivatives, IS30 family
JYQ65_RS06160	COG1113	amino acid transport
JYQ65_RS06170	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
JYQ65_RS06190	COG0105	UTP biosynthetic process
JYQ65_RS06195	COG1695	Transcriptional regulator
JYQ65_RS06200	COG3479	Phenolic acid decarboxylase
JYQ65_RS06220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JYQ65_RS06225	COG2918	glutathione biosynthetic process
JYQ65_RS06225	COG1181	Belongs to the D-alanine--D-alanine ligase family
JYQ65_RS06230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JYQ65_RS06235	COG0402	S-adenosylhomocysteine deaminase activity
JYQ65_RS06240	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JYQ65_RS06280	COG2801	Transposase and inactivated derivatives
JYQ65_RS06290	COG0390	transport system, permease component
JYQ65_RS06300	COG0028	Belongs to the TPP enzyme family
JYQ65_RS06335	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JYQ65_RS06335	COG2190	(PTS) system
JYQ65_RS06335	COG1263	PTS System
JYQ65_RS06340	COG2188	Transcriptional regulator
JYQ65_RS06345	COG0366	Alpha amylase catalytic
JYQ65_RS06370	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JYQ65_RS06415	COG0582	viral genome integration into host DNA
JYQ65_RS06435	COG2801	Transposase and inactivated derivatives
JYQ65_RS06445	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JYQ65_RS06455	COG1397	ADP-ribosylglycohydrolase
JYQ65_RS06485	COG2610	gluconate transmembrane transporter activity
JYQ65_RS06490	COG1609	Transcriptional regulator
JYQ65_RS06500	COG0436	Aminotransferase
JYQ65_RS06535	COG2181	nitrate reductase activity
JYQ65_RS06545	COG1140	nitrate reductase beta subunit
JYQ65_RS06550	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
JYQ65_RS06555	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JYQ65_RS06570	COG0315	cyclic pyranopterin monophosphate synthase activity
JYQ65_RS06595	COG2197	response regulator
JYQ65_RS06620	COG2226	methyltransferase
JYQ65_RS06630	COG2151	metal-sulfur cluster biosynthetic enzyme
JYQ65_RS06635	COG2223	nitrite transmembrane transporter activity
JYQ65_RS06640	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JYQ65_RS06660	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JYQ65_RS06665	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
JYQ65_RS06670	COG1252	NADH dehydrogenase
JYQ65_RS06675	COG2151	metal-sulfur cluster biosynthetic enzyme
JYQ65_RS06695	COG2826	transposase and inactivated derivatives, IS30 family
JYQ65_RS06705	COG0719	Fe-S assembly protein
JYQ65_RS06710	COG0822	iron-sulfur transferase activity
JYQ65_RS06715	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JYQ65_RS06720	COG0719	Fe-S assembly protein
JYQ65_RS06755	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JYQ65_RS06760	COG0436	Aminotransferase
JYQ65_RS06765	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JYQ65_RS06770	COG0287	Prephenate dehydrogenase
JYQ65_RS06775	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
JYQ65_RS06785	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
JYQ65_RS06790	COG1605	Chorismate mutase
JYQ65_RS06790	COG0077	Prephenate dehydratase
JYQ65_RS06795	COG0738	Major facilitator superfamily
JYQ65_RS06800	COG3104	oligopeptide transport
JYQ65_RS06810	COG0561	phosphatase activity
JYQ65_RS06825	COG0477	Major facilitator Superfamily
JYQ65_RS06855	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JYQ65_RS06860	COG1942	4-Oxalocrotonate Tautomerase
JYQ65_RS06865	COG0569	domain protein
JYQ65_RS06865	COG0475	glutathione-regulated potassium exporter activity
JYQ65_RS06880	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JYQ65_RS06885	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JYQ65_RS06895	COG0477	Major facilitator Superfamily
JYQ65_RS06905	COG1253	flavin adenine dinucleotide binding
JYQ65_RS06910	COG2814	Major facilitator Superfamily
JYQ65_RS06925	COG0583	DNA-binding transcription factor activity
JYQ65_RS06935	COG0095	Lipoate-protein ligase
JYQ65_RS06970	COG1687	branched-chain amino acid
JYQ65_RS06985	COG0460	homoserine dehydrogenase
JYQ65_RS06990	COG0083	homoserine kinase activity
JYQ65_RS07000	COG0702	epimerase
JYQ65_RS07005	COG1418	mRNA catabolic process
JYQ65_RS07010	COG3022	response to hydroperoxide
JYQ65_RS07020	COG1307	EDD domain protein, DegV family
JYQ65_RS07025	COG1293	RNA-binding protein homologous to eukaryotic snRNP
JYQ65_RS07040	COG3328	transposase activity
JYQ65_RS07050	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JYQ65_RS07055	COG0505	Belongs to the CarA family
JYQ65_RS07060	COG0564	pseudouridine synthase activity
JYQ65_RS07075	COG0328	RNA-DNA hybrid ribonuclease activity
JYQ65_RS07085	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JYQ65_RS07090	COG0765	amino acid transport
JYQ65_RS07095	COG1216	Glycosyl transferase, family 2
JYQ65_RS07095	COG1442	glycosyl transferase family 8
JYQ65_RS07115	COG0154	amidase activity
JYQ65_RS07125	COG0116	Belongs to the methyltransferase superfamily
JYQ65_RS07130	COG1051	belongs to the nudix hydrolase family
JYQ65_RS07150	COG3599	regulation of cell shape
JYQ65_RS07155	COG4474	Belongs to the UPF0398 family
JYQ65_RS07160	COG3331	DNA recombination
JYQ65_RS07170	COG0697	spore germination
JYQ65_RS07175	COG0667	Aldo Keto reductase
JYQ65_RS07200	COG1199	ATP-dependent helicase activity
JYQ65_RS07200	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JYQ65_RS07225	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JYQ65_RS07230	COG0675	Transposase, IS605 OrfB family
JYQ65_RS07240	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
JYQ65_RS07240	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JYQ65_RS07245	COG0561	phosphatase activity
JYQ65_RS07260	COG2801	Transposase and inactivated derivatives
JYQ65_RS07300	COG2261	transglycosylase associated protein
JYQ65_RS07360	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JYQ65_RS07370	COG0028	Belongs to the TPP enzyme family
JYQ65_RS07385	COG0167	dihydroorotate dehydrogenase activity
JYQ65_RS07390	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JYQ65_RS07395	COG0505	Belongs to the CarA family
JYQ65_RS07400	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JYQ65_RS07410	COG4336	lyase activity
JYQ65_RS07465	COG0163	prenyltransferase activity
JYQ65_RS07500	COG1518	maintenance of DNA repeat elements
JYQ65_RS07515	COG1857	crispr-associated protein
JYQ65_RS07535	COG0335	large ribosomal subunit rRNA binding
JYQ65_RS07540	COG0531	amino acid
JYQ65_RS07545	COG0336	Belongs to the RNA methyltransferase TrmD family
JYQ65_RS07550	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JYQ65_RS07555	COG1837	Belongs to the UPF0109 family
JYQ65_RS07560	COG0228	four-way junction DNA binding
JYQ65_RS07570	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JYQ65_RS07575	COG0581	inorganic phosphate transmembrane transporter activity
JYQ65_RS07580	COG0573	inorganic phosphate transmembrane transporter activity
JYQ65_RS07585	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
JYQ65_RS07590	COG0745	RESPONSE REGULATOR receiver
JYQ65_RS07605	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JYQ65_RS07610	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
JYQ65_RS07615	COG0552	protein localization to endoplasmic reticulum
JYQ65_RS07620	COG1196	nuclear chromosome segregation
JYQ65_RS07625	COG0571	ribonuclease III activity
JYQ65_RS07630	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JYQ65_RS07635	COG0416	fatty acid biosynthetic process
JYQ65_RS07640	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JYQ65_RS07645	COG1461	Dihydroxyacetone kinase
JYQ65_RS07655	COG0227	Belongs to the bacterial ribosomal protein bL28 family
JYQ65_RS07660	COG1564	THIamine pyrophosphokinase
JYQ65_RS07665	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JYQ65_RS07670	COG1162	GTPase activity
JYQ65_RS07675	COG0515	serine threonine protein kinase
JYQ65_RS07675	COG2815	serine threonine protein kinase
JYQ65_RS07685	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JYQ65_RS07685	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JYQ65_RS07690	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JYQ65_RS07695	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JYQ65_RS07700	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JYQ65_RS07705	COG1758	RNA polymerase activity
JYQ65_RS07720	COG0497	DNA recombination
JYQ65_RS07725	COG1438	arginine binding
JYQ65_RS07730	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
JYQ65_RS07745	COG1570	exodeoxyribonuclease VII activity
JYQ65_RS07750	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JYQ65_RS07755	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JYQ65_RS07760	COG1302	Protein conserved in bacteria
JYQ65_RS07765	COG0006	proline dipeptidase activity
JYQ65_RS07770	COG0211	Belongs to the bacterial ribosomal protein bL27 family
JYQ65_RS07780	COG0261	This protein binds to 23S rRNA in the presence of protein L20
JYQ65_RS07785	COG1309	transcriptional regulator
JYQ65_RS07815	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JYQ65_RS07825	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JYQ65_RS07830	COG1940	carbohydrate kinase activity
JYQ65_RS07845	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JYQ65_RS07850	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JYQ65_RS07855	COG0768	penicillin binding
JYQ65_RS07865	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JYQ65_RS07870	COG0572	uridine kinase
JYQ65_RS07875	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JYQ65_RS07875	COG0072	phenylalanine-tRNA ligase activity
JYQ65_RS07880	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JYQ65_RS07885	COG1733	regulation of RNA biosynthetic process
JYQ65_RS07895	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JYQ65_RS07900	COG1254	Belongs to the acylphosphatase family
JYQ65_RS07905	COG0706	membrane insertase activity
JYQ65_RS07910	COG0242	peptide deformylase activity
JYQ65_RS07920	COG5002	protein histidine kinase activity
JYQ65_RS07925	COG0745	RESPONSE REGULATOR receiver
JYQ65_RS07930	COG0333	Belongs to the bacterial ribosomal protein bL32 family
JYQ65_RS07940	COG1323	Belongs to the UPF0348 family
JYQ65_RS07945	COG2226	methyltransferase
JYQ65_RS07950	COG0799	negative regulation of ribosome biogenesis
JYQ65_RS07960	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JYQ65_RS07970	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JYQ65_RS07985	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
JYQ65_RS07990	COG0291	Belongs to the bacterial ribosomal protein bL35 family
JYQ65_RS07995	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
JYQ65_RS08000	COG1484	DNA-dependent DNA replication
JYQ65_RS08010	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JYQ65_RS08015	COG0237	dephospho-CoA kinase activity
JYQ65_RS08020	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
JYQ65_RS08035	COG0670	Belongs to the BI1 family
JYQ65_RS08040	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JYQ65_RS08045	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JYQ65_RS08050	COG3118	belongs to the thioredoxin family
JYQ65_RS08060	COG0220	tRNA (guanine-N7-)-methyltransferase activity
JYQ65_RS08070	COG1131	(ABC) transporter
JYQ65_RS08075	COG0537	adenosine 5'-monophosphoramidase activity
JYQ65_RS08090	COG3481	metal-dependent phosphohydrolase, HD sub domain
JYQ65_RS08095	COG3679	Belongs to the UPF0342 family
JYQ65_RS08100	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JYQ65_RS08105	COG0018	arginyl-trna synthetase
JYQ65_RS08125	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JYQ65_RS08130	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JYQ65_RS08140	COG0302	gtp cyclohydrolase
JYQ65_RS08145	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JYQ65_RS08145	COG0302	gtp cyclohydrolase
JYQ65_RS08160	COG1609	Transcriptional regulator
JYQ65_RS08170	COG1428	Deoxynucleoside kinase
JYQ65_RS08175	COG1388	LysM domain
JYQ65_RS08175	COG1705	Flagellar rod assembly protein muramidase FlgJ
JYQ65_RS08185	COG0589	response to stress
JYQ65_RS08190	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JYQ65_RS08195	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
JYQ65_RS08205	COG2244	polysaccharide biosynthetic process
JYQ65_RS08215	COG0495	leucyl-tRNA aminoacylation
JYQ65_RS08220	COG0671	phosphoesterase, PA-phosphatase related
JYQ65_RS08225	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JYQ65_RS08230	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JYQ65_RS08235	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JYQ65_RS08245	COG2818	Glycosylase
JYQ65_RS08250	COG2814	Major facilitator Superfamily
JYQ65_RS08260	COG1113	amino acid transport
JYQ65_RS08300	COG1607	acyl-coa hydrolase
JYQ65_RS08315	COG2233	PERMEase
JYQ65_RS08325	COG0602	queuosine metabolic process
JYQ65_RS08335	COG0765	amino acid transport
JYQ65_RS08340	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JYQ65_RS08345	COG2076	Multidrug Resistance protein
JYQ65_RS08360	COG2826	transposase and inactivated derivatives, IS30 family
JYQ65_RS08445	COG0438	transferase activity, transferring glycosyl groups
JYQ65_RS08450	COG0438	transferase activity, transferring glycosyl groups
JYQ65_RS08455	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JYQ65_RS08470	COG0542	response to heat
JYQ65_RS08480	COG1335	isochorismatase
JYQ65_RS08485	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JYQ65_RS08500	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JYQ65_RS08515	COG2826	transposase and inactivated derivatives, IS30 family
JYQ65_RS08535	COG1131	(ABC) transporter
JYQ65_RS08540	COG2188	Transcriptional regulator
JYQ65_RS08545	COG1088	dTDP-glucose 4,6-dehydratase activity
JYQ65_RS08555	COG1215	transferase activity, transferring glycosyl groups
JYQ65_RS08560	COG0438	transferase activity, transferring glycosyl groups
JYQ65_RS08565	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
JYQ65_RS08575	COG0463	Glycosyl transferase, family 2
JYQ65_RS08580	COG0628	permease
JYQ65_RS08585	COG0463	Glycosyl transferase, family 2
JYQ65_RS08595	COG0791	NLP P60 protein
JYQ65_RS08635	COG1705	Flagellar rod assembly protein muramidase FlgJ
JYQ65_RS08650	COG0562	UDP-galactopyranose mutase
JYQ65_RS08670	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JYQ65_RS08675	COG2137	regulation of response to DNA damage stimulus
JYQ65_RS08690	COG1295	ribonuclease BN
JYQ65_RS08695	COG1368	sulfuric ester hydrolase activity
JYQ65_RS08700	COG0024	Methionine aminopeptidase
JYQ65_RS08705	COG0716	FMN binding
JYQ65_RS08710	COG2246	polysaccharide biosynthetic process
JYQ65_RS08725	COG0513	Belongs to the DEAD box helicase family
JYQ65_RS08750	COG2918	glutathione biosynthetic process
JYQ65_RS08760	COG4841	protein insertion into membrane
JYQ65_RS08765	COG0488	(ABC) transporter
JYQ65_RS08775	COG2826	transposase and inactivated derivatives, IS30 family
JYQ65_RS08790	COG0783	Belongs to the Dps family
JYQ65_RS08800	COG1316	TRANSCRIPTIONal
JYQ65_RS08805	COG1846	Transcriptional regulator
JYQ65_RS08810	COG2223	nitrite transmembrane transporter activity
JYQ65_RS08820	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JYQ65_RS08835	COG2226	methyltransferase
JYQ65_RS08855	COG3760	aminoacyl-tRNA metabolism involved in translational fidelity
JYQ65_RS08865	COG1757	Na H antiporter
JYQ65_RS08890	COG2801	Transposase and inactivated derivatives
JYQ65_RS08930	COG2801	Transposase and inactivated derivatives
JYQ65_RS08940	COG3328	transposase activity
JYQ65_RS08950	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JYQ65_RS08980	COG0675	Transposase, IS605 OrfB family
JYQ65_RS08990	COG3328	transposase activity
JYQ65_RS09025	COG0732	type I restriction modification DNA specificity domain
JYQ65_RS09035	COG4974	Belongs to the 'phage' integrase family
JYQ65_RS09045	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
JYQ65_RS09085	COG2826	transposase and inactivated derivatives, IS30 family
JYQ65_RS09135	COG2801	Transposase and inactivated derivatives
JYQ65_RS09160	COG1802	Transcriptional regulator
JYQ65_RS09160	COG4626	Terminase
JYQ65_RS09165	COG4695	Portal protein
JYQ65_RS09170	COG0740	serine-type endopeptidase activity
JYQ65_RS09225	COG3328	transposase activity
JYQ65_RS09235	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JYQ65_RS09240	COG1597	lipid kinase activity
JYQ65_RS09245	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JYQ65_RS09250	COG0154	amidase activity
JYQ65_RS09255	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JYQ65_RS09260	COG4851	CamS sex pheromone cAM373 precursor
JYQ65_RS09265	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JYQ65_RS09280	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JYQ65_RS09285	COG1705	Flagellar rod assembly protein muramidase FlgJ
JYQ65_RS09300	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
JYQ65_RS09305	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JYQ65_RS09310	COG0101	tRNA pseudouridine synthase activity
JYQ65_RS09320	COG1122	ATPase activity
JYQ65_RS09325	COG1122	ATPase activity
JYQ65_RS09330	COG0203	ribosomal protein L17
JYQ65_RS09335	COG0202	RNA polymerase activity
JYQ65_RS09340	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JYQ65_RS09345	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JYQ65_RS09350	COG0257	Belongs to the bacterial ribosomal protein bL36 family
JYQ65_RS09355	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
JYQ65_RS09360	COG0563	adenylate kinase activity
JYQ65_RS09370	COG0200	Binds to the 23S rRNA
JYQ65_RS09375	COG1841	ribosomal large subunit assembly
JYQ65_RS09380	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JYQ65_RS09385	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
JYQ65_RS09390	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JYQ65_RS09395	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JYQ65_RS09400	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JYQ65_RS09405	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
JYQ65_RS09410	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
JYQ65_RS09415	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JYQ65_RS09425	COG0255	Belongs to the universal ribosomal protein uL29 family
JYQ65_RS09430	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
JYQ65_RS09435	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JYQ65_RS09440	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
JYQ65_RS09445	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JYQ65_RS09450	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JYQ65_RS09455	COG0089	rRNA binding
JYQ65_RS09460	COG0088	Forms part of the polypeptide exit tunnel
JYQ65_RS09465	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JYQ65_RS09470	COG0051	transcription antitermination factor activity, RNA binding
JYQ65_RS09475	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JYQ65_RS09480	COG0049	tRNA binding
JYQ65_RS09485	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
JYQ65_RS09500	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
JYQ65_RS09505	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JYQ65_RS09510	COG0085	RNA polymerase activity
JYQ65_RS09520	COG0542	response to heat
JYQ65_RS09525	COG4463	regulation of RNA biosynthetic process
JYQ65_RS09530	COG1064	alcohol dehydrogenase
JYQ65_RS09545	COG0110	maltose O-acetyltransferase activity
JYQ65_RS09565	COG0789	Transcriptional regulator
JYQ65_RS09580	COG1968	undecaprenyl-diphosphatase activity
JYQ65_RS09590	COG1028	Short-chain dehydrogenase reductase Sdr
JYQ65_RS09595	COG1028	Short-chain dehydrogenase reductase Sdr
JYQ65_RS09625	COG1428	Deoxynucleoside kinase
JYQ65_RS09630	COG0833	amino acid
JYQ65_RS09665	COG2826	transposase and inactivated derivatives, IS30 family
JYQ65_RS09670	COG1278	Cold shock
JYQ65_RS09725	COG2814	Major facilitator Superfamily
JYQ65_RS09740	COG0564	pseudouridine synthase activity
JYQ65_RS09750	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
JYQ65_RS09750	COG0392	lysyltransferase activity
JYQ65_RS09755	COG0693	protein deglycase activity
JYQ65_RS09760	COG0657	acetylesterase activity
JYQ65_RS09780	COG2267	carboxylic ester hydrolase activity
JYQ65_RS09800	COG3052	prosthetic group binding
JYQ65_RS09810	COG0281	malic enzyme
JYQ65_RS09820	COG0471	metal ion transport
JYQ65_RS09825	COG0039	L-malate dehydrogenase activity
JYQ65_RS09830	COG1053	succinate dehydrogenase
JYQ65_RS09835	COG0114	fumarate hydratase activity
JYQ65_RS09840	COG1053	succinate dehydrogenase
JYQ65_RS09840	COG0431	NADPH-dependent FMN reductase
JYQ65_RS09840	COG3976	FMN-binding domain protein
JYQ65_RS09845	COG0431	NADPH-dependent FMN reductase
JYQ65_RS09845	COG1053	succinate dehydrogenase
JYQ65_RS09845	COG3976	FMN-binding domain protein
JYQ65_RS09850	COG0281	malic enzyme
JYQ65_RS09855	COG0583	DNA-binding transcription factor activity
JYQ65_RS09870	COG0657	acetylesterase activity
JYQ65_RS09880	COG1263	PTS System
JYQ65_RS09880	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JYQ65_RS09880	COG2190	(PTS) system
JYQ65_RS09900	COG0583	DNA-binding transcription factor activity
JYQ65_RS09905	COG2326	polyphosphate kinase activity
JYQ65_RS09930	COG1686	Belongs to the peptidase S11 family
JYQ65_RS09940	COG2706	6-phosphogluconolactonase activity
JYQ65_RS09960	COG0494	nUDIX hydrolase
JYQ65_RS09990	COG1854	S-ribosylhomocysteine lyase activity
JYQ65_RS09995	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JYQ65_RS10010	COG1011	Hydrolase
JYQ65_RS10015	COG2502	aspartate--ammonia ligase
JYQ65_RS10030	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JYQ65_RS10040	COG0789	Transcriptional regulator
JYQ65_RS10045	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
JYQ65_RS10050	COG1984	allophanate hydrolase subunit 2
JYQ65_RS10060	COG0439	Biotin carboxylase
JYQ65_RS10065	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
JYQ65_RS10070	COG1914	H( )-stimulated, divalent metal cation uptake system
JYQ65_RS10085	COG3118	belongs to the thioredoxin family
JYQ65_RS10115	COG0531	amino acid
JYQ65_RS10125	COG0494	nUDIX hydrolase
JYQ65_RS10130	COG0110	maltose O-acetyltransferase activity
JYQ65_RS10135	COG0165	Argininosuccinate lyase
JYQ65_RS10155	COG1136	(ABC) transporter
JYQ65_RS10155	COG0577	efflux transmembrane transporter activity
JYQ65_RS10170	COG0577	efflux transmembrane transporter activity
JYQ65_RS10170	COG1136	(ABC) transporter
JYQ65_RS10180	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
JYQ65_RS10185	COG0393	Putative heavy-metal-binding
JYQ65_RS10195	COG2070	2-Nitropropane dioxygenase
JYQ65_RS10200	COG0640	Transcriptional regulator
JYQ65_RS10225	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JYQ65_RS10235	COG0519	Catalyzes the synthesis of GMP from XMP
JYQ65_RS10240	COG2357	RelA SpoT domain protein
JYQ65_RS10245	COG0745	RESPONSE REGULATOR receiver
JYQ65_RS10250	COG5002	protein histidine kinase activity
JYQ65_RS10255	COG1072	(Pantothenic acid kinase))
JYQ65_RS10265	COG1028	Short-chain dehydrogenase reductase Sdr
JYQ65_RS10270	COG1368	sulfuric ester hydrolase activity
JYQ65_RS10280	COG3973	AAA domain
JYQ65_RS10285	COG0586	Pfam SNARE associated Golgi protein
JYQ65_RS10295	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JYQ65_RS10300	COG4948	Mandelate Racemase Muconate Lactonizing
JYQ65_RS10310	COG0531	amino acid
JYQ65_RS10325	COG1511	domain protein
JYQ65_RS10335	COG2017	converts alpha-aldose to the beta-anomer
JYQ65_RS10350	COG0735	belongs to the Fur family
JYQ65_RS10355	COG0194	GDP metabolic process
JYQ65_RS10365	COG0531	amino acid
JYQ65_RS10370	COG2936	dipeptidyl-peptidase activity
JYQ65_RS10375	COG0675	Transposase, IS605 OrfB family
JYQ65_RS10385	COG2267	carboxylic ester hydrolase activity
JYQ65_RS10400	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JYQ65_RS10405	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JYQ65_RS10410	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JYQ65_RS10420	COG1376	ErfK ybiS ycfS ynhG family protein
JYQ65_RS10435	COG0488	(ABC) transporter
JYQ65_RS10445	COG4120	Belongs to the binding-protein-dependent transport system permease family
JYQ65_RS10450	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
JYQ65_RS10460	COG0004	ammonium transporteR
JYQ65_RS10465	COG0534	Mate efflux family protein
JYQ65_RS10470	COG1940	carbohydrate kinase activity
JYQ65_RS10480	COG1609	Transcriptional regulator
JYQ65_RS10485	COG2084	Dehydrogenase
JYQ65_RS10495	COG3118	belongs to the thioredoxin family
JYQ65_RS10500	COG0861	Integral membrane protein TerC family
JYQ65_RS10505	COG0564	pseudouridine synthase activity
JYQ65_RS10515	COG2233	PERMEase
JYQ65_RS10530	COG0702	epimerase
JYQ65_RS10535	COG0406	alpha-ribazole phosphatase activity
JYQ65_RS10540	COG1368	sulfuric ester hydrolase activity
JYQ65_RS10550	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JYQ65_RS10560	COG2217	Heavy metal translocating P-type atpase
JYQ65_RS10565	COG2217	Heavy metal translocating P-type atpase
JYQ65_RS10570	COG0492	ferredoxin-NADP+ reductase activity
JYQ65_RS10575	COG1957	nucleoside hydrolase
JYQ65_RS10585	COG1122	ATPase activity
JYQ65_RS10605	COG0095	Lipoate-protein ligase
JYQ65_RS10620	COG1396	sequence-specific DNA binding
JYQ65_RS10640	COG0589	response to stress
JYQ65_RS10665	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JYQ65_RS10670	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
JYQ65_RS10690	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
JYQ65_RS10695	COG1606	tRNA processing
JYQ65_RS10700	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JYQ65_RS10705	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
JYQ65_RS10725	COG3875	lactate racemase activity
JYQ65_RS10730	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JYQ65_RS10745	COG3328	transposase activity
JYQ65_RS10770	COG1869	D-ribose catabolic process
JYQ65_RS10780	COG2390	Transcriptional regulator
JYQ65_RS10785	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JYQ65_RS10795	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JYQ65_RS10800	COG3775	system Galactitol-specific IIC component
JYQ65_RS10805	COG1609	Transcriptional regulator
JYQ65_RS10830	COG0561	phosphatase activity
JYQ65_RS10835	COG2188	Transcriptional regulator
JYQ65_RS10840	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JYQ65_RS10870	COG1253	flavin adenine dinucleotide binding
JYQ65_RS10885	COG2807	transmembrane transport
JYQ65_RS10895	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
JYQ65_RS10900	COG0589	response to stress
JYQ65_RS10905	COG1522	sequence-specific DNA binding
JYQ65_RS10910	COG1028	Short-chain dehydrogenase reductase Sdr
JYQ65_RS10915	COG1609	Transcriptional regulator
JYQ65_RS10920	COG1164	Oligoendopeptidase f
JYQ65_RS10925	COG1301	dicarboxylic acid transport
JYQ65_RS10945	COG0277	FAD linked oxidase domain protein
JYQ65_RS10960	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JYQ65_RS10960	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JYQ65_RS11000	COG2826	transposase and inactivated derivatives, IS30 family
JYQ65_RS11040	COG2217	Heavy metal translocating P-type atpase
JYQ65_RS11060	COG0577	efflux transmembrane transporter activity
JYQ65_RS11090	COG1609	Transcriptional regulator
JYQ65_RS11095	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
JYQ65_RS11100	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JYQ65_RS11110	COG2365	Tyrosine phosphatase family
JYQ65_RS11115	COG1881	PFAM PEBP family protein
JYQ65_RS11125	COG1126	abc transporter atp-binding protein
JYQ65_RS11130	COG0765	amino acid transport
JYQ65_RS11135	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JYQ65_RS11145	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JYQ65_RS11150	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JYQ65_RS11160	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
JYQ65_RS11165	COG3590	peptidase
JYQ65_RS11170	COG2252	PERMEase
JYQ65_RS11190	COG2094	Belongs to the DNA glycosylase MPG family
JYQ65_RS11195	COG3189	MarR family transcriptional regulator
JYQ65_RS11205	COG2249	NAD(P)H dehydrogenase (quinone) activity
JYQ65_RS11215	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
JYQ65_RS11220	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JYQ65_RS11235	COG1609	Transcriptional regulator
JYQ65_RS11240	COG1388	LysM domain
JYQ65_RS11240	COG1705	Flagellar rod assembly protein muramidase FlgJ
JYQ65_RS11245	COG0640	Transcriptional regulator
JYQ65_RS11250	COG0675	Transposase, IS605 OrfB family
JYQ65_RS11305	COG3328	transposase activity
JYQ65_RS11315	COG1914	H( )-stimulated, divalent metal cation uptake system
JYQ65_RS11325	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JYQ65_RS11350	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JYQ65_RS11355	COG0367	asparagine synthase
JYQ65_RS11360	COG0833	amino acid
JYQ65_RS11365	COG1970	mechanosensitive ion channel activity
JYQ65_RS11370	COG0445	tRNA wobble uridine modification
JYQ65_RS11375	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JYQ65_RS11385	COG0706	membrane insertase activity
JYQ65_RS11390	COG0594	ribonuclease P activity
JYQ65_RS11395	COG0230	Belongs to the bacterial ribosomal protein bL34 family