locus-tag	class	description
LM596_RS00010	COG0592	DNA-directed DNA polymerase activity
LM596_RS00015	COG0281	malic enzyme
LM596_RS00020	COG2501	S4 domain
LM596_RS00030	COG0187	DNA topoisomerase II activity
LM596_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LM596_RS00040	COG0360	Binds together with S18 to 16S ribosomal RNA
LM596_RS00045	COG0629	single-stranded DNA binding
LM596_RS00050	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LM596_RS00065	COG0359	binds to the 23S rRNA
LM596_RS00070	COG0305	Participates in initiation and elongation during chromosome replication
LM596_RS00080	COG1607	acyl-coa hydrolase
LM596_RS00085	COG3842	ATPase activity
LM596_RS00090	COG1175	transmembrane transport
LM596_RS00095	COG0395	ABC-type sugar transport system, permease component
LM596_RS00125	COG1737	Transcriptional regulator
LM596_RS00130	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LM596_RS00140	COG3716	PTS system mannose fructose sorbose family IID component
LM596_RS00150	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LM596_RS00155	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LM596_RS00160	COG4948	Mandelate Racemase Muconate Lactonizing
LM596_RS00190	COG0745	RESPONSE REGULATOR receiver
LM596_RS00210	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LM596_RS00215	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LM596_RS00220	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LM596_RS00225	COG2423	ornithine cyclodeaminase activity
LM596_RS00230	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LM596_RS00240	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LM596_RS00240	COG2190	(PTS) system
LM596_RS00240	COG1263	PTS System
LM596_RS00255	COG0583	DNA-binding transcription factor activity
LM596_RS00260	COG1132	(ABC) transporter
LM596_RS00265	COG1132	(ABC) transporter
LM596_RS00275	COG2267	carboxylic ester hydrolase activity
LM596_RS00280	COG0110	maltose O-acetyltransferase activity
LM596_RS00295	COG1428	Deoxynucleoside kinase
LM596_RS00320	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LM596_RS00340	COG0577	efflux transmembrane transporter activity
LM596_RS00340	COG1136	(ABC) transporter
LM596_RS00395	COG0477	Major facilitator Superfamily
LM596_RS00465	COG0095	Lipoate-protein ligase
LM596_RS00480	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LM596_RS00485	COG2814	Major facilitator Superfamily
LM596_RS00500	COG1349	DNA-binding transcription factor activity
LM596_RS00505	COG1105	Belongs to the carbohydrate kinase PfkB family
LM596_RS00510	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LM596_RS00510	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LM596_RS00510	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LM596_RS00525	COG0460	homoserine dehydrogenase
LM596_RS00550	COG0562	UDP-galactopyranose mutase
LM596_RS00560	COG1442	glycosyl transferase family 8
LM596_RS00560	COG1216	Glycosyl transferase, family 2
LM596_RS00575	COG0738	Major facilitator superfamily
LM596_RS00580	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LM596_RS00590	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LM596_RS00595	COG0287	Prephenate dehydrogenase
LM596_RS00600	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LM596_RS00610	COG1307	EDD domain protein, DegV family
LM596_RS00615	COG4948	Mandelate Racemase Muconate Lactonizing
LM596_RS00625	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
LM596_RS00630	COG1169	isochorismate synthase
LM596_RS00635	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LM596_RS00640	COG3875	lactate racemase activity
LM596_RS00645	COG1691	(AIR) carboxylase
LM596_RS00650	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
LM596_RS00655	COG1606	tRNA processing
LM596_RS00660	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LM596_RS00675	COG1012	belongs to the aldehyde dehydrogenase family
LM596_RS00680	COG0738	Major facilitator superfamily
LM596_RS00685	COG0710	3-dehydroquinate dehydratase activity
LM596_RS00690	COG0738	Major facilitator superfamily
LM596_RS00695	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LM596_RS00700	COG0583	DNA-binding transcription factor activity
LM596_RS00705	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LM596_RS00720	COG0196	riboflavin kinase activity
LM596_RS00725	COG1053	succinate dehydrogenase
LM596_RS00735	COG1556	Lactate utilization protein
LM596_RS00740	COG1139	Iron-sulfur cluster binding protein
LM596_RS00745	COG0247	lactate metabolic process
LM596_RS00750	COG0783	Belongs to the Dps family
LM596_RS00755	COG0431	NADPH-dependent FMN reductase
LM596_RS00775	COG3402	PFAM membrane-flanked domain
LM596_RS00785	COG2365	Tyrosine phosphatase family
LM596_RS00805	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LM596_RS00810	COG1388	LysM domain
LM596_RS00810	COG1705	Flagellar rod assembly protein muramidase FlgJ
LM596_RS00820	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LM596_RS00825	COG3711	transcriptional antiterminator
LM596_RS00825	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LM596_RS00845	COG0191	fructose-bisphosphate aldolase activity
LM596_RS00860	COG0667	Aldo Keto reductase
LM596_RS00875	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LM596_RS00885	COG0308	aminopeptidase N
LM596_RS00890	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LM596_RS00895	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LM596_RS00905	COG0693	protein deglycase activity
LM596_RS00910	COG4948	Mandelate Racemase Muconate Lactonizing
LM596_RS00915	COG3842	ATPase activity
LM596_RS00920	COG4120	Belongs to the binding-protein-dependent transport system permease family
LM596_RS00940	COG0561	phosphatase activity
LM596_RS00945	COG2814	Major facilitator Superfamily
LM596_RS00950	COG0584	glycerophosphoryl diester phosphodiesterase
LM596_RS00955	COG0477	Major facilitator Superfamily
LM596_RS00960	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LM596_RS00970	COG2261	transglycosylase associated protein
LM596_RS00975	COG1268	BioY protein
LM596_RS00980	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LM596_RS01000	COG1053	succinate dehydrogenase
LM596_RS01000	COG3976	FMN-binding domain protein
LM596_RS01005	COG0561	phosphatase activity
LM596_RS01010	COG0384	phenazine biosynthesis protein PhzF
LM596_RS01015	COG1307	EDD domain protein, DegV family
LM596_RS01025	COG0604	alcohol dehydrogenase
LM596_RS01025	COG3321	synthase
LM596_RS01030	COG1136	(ABC) transporter
LM596_RS01030	COG0577	efflux transmembrane transporter activity
LM596_RS01035	COG1597	lipid kinase activity
LM596_RS01040	COG0667	Aldo Keto reductase
LM596_RS01070	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
LM596_RS01080	COG0488	(ABC) transporter
LM596_RS01090	COG0028	Belongs to the TPP enzyme family
LM596_RS01105	COG1164	Oligoendopeptidase f
LM596_RS01115	COG1253	flavin adenine dinucleotide binding
LM596_RS01165	COG0861	Integral membrane protein TerC family
LM596_RS01170	COG0561	phosphatase activity
LM596_RS01180	COG0667	Aldo Keto reductase
LM596_RS01185	COG3757	hydrolase, family 25
LM596_RS01185	COG3409	Peptidoglycan-binding domain 1 protein
LM596_RS01190	COG4708	membrane
LM596_RS01205	COG2267	carboxylic ester hydrolase activity
LM596_RS01215	COG0531	amino acid
LM596_RS01220	COG0194	GDP metabolic process
LM596_RS01225	COG0735	belongs to the Fur family
LM596_RS01240	COG1126	abc transporter atp-binding protein
LM596_RS01245	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LM596_RS01250	COG0765	amino acid transport
LM596_RS01255	COG0765	amino acid transport
LM596_RS01260	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LM596_RS01265	COG4166	transmembrane transport
LM596_RS01270	COG0601	transmembrane transport
LM596_RS01275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LM596_RS01280	COG0444	Belongs to the ABC transporter superfamily
LM596_RS01285	COG4608	Belongs to the ABC transporter superfamily
LM596_RS01295	COG0586	Pfam SNARE associated Golgi protein
LM596_RS01300	COG3973	AAA domain
LM596_RS01315	COG0789	Transcriptional regulator
LM596_RS01320	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
LM596_RS01325	COG1263	PTS System
LM596_RS01325	COG2190	(PTS) system
LM596_RS01325	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LM596_RS01330	COG2723	6-phospho-beta-galactosidase activity
LM596_RS01335	COG3711	transcriptional antiterminator
LM596_RS01355	COG1263	PTS System
LM596_RS01355	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LM596_RS01375	COG1621	beta-fructofuranosidase activity
LM596_RS01380	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LM596_RS01385	COG1132	(ABC) transporter
LM596_RS01390	COG1132	(ABC) transporter
LM596_RS01405	COG2814	Major facilitator Superfamily
LM596_RS01415	COG1113	amino acid transport
LM596_RS01420	COG0583	DNA-binding transcription factor activity
LM596_RS01435	COG1737	Transcriptional regulator
LM596_RS01440	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LM596_RS01445	COG2723	6-phospho-beta-galactosidase activity
LM596_RS01450	COG1447	Phosphotransferase system cellobiose-specific component IIA
LM596_RS01465	COG2197	response regulator
LM596_RS01470	COG0386	Belongs to the glutathione peroxidase family
LM596_RS01475	COG1914	H( )-stimulated, divalent metal cation uptake system
LM596_RS01480	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
LM596_RS01485	COG4336	lyase activity
LM596_RS01490	COG0439	Biotin carboxylase
LM596_RS01495	COG0511	ligase activity, forming carbon-carbon bonds
LM596_RS01500	COG1984	allophanate hydrolase subunit 2
LM596_RS01505	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
LM596_RS01510	COG0471	metal ion transport
LM596_RS01520	COG0583	DNA-binding transcription factor activity
LM596_RS01525	COG4152	abc transporter atp-binding protein
LM596_RS01530	COG1668	transmembrane transport
LM596_RS01535	COG1136	(ABC) transporter
LM596_RS01545	COG1725	Transcriptional regulator
LM596_RS01550	COG1131	(ABC) transporter
LM596_RS01565	COG0564	pseudouridine synthase activity
LM596_RS01575	COG1278	Cold shock
LM596_RS01580	COG2814	Major facilitator Superfamily
LM596_RS01595	COG0577	efflux transmembrane transporter activity
LM596_RS01600	COG1136	(ABC) transporter
LM596_RS01620	COG1959	2 iron, 2 sulfur cluster binding
LM596_RS01625	COG0028	Belongs to the TPP enzyme family
LM596_RS01630	COG0833	amino acid
LM596_RS01710	COG4463	regulation of RNA biosynthetic process
LM596_RS01730	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
LM596_RS01735	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LM596_RS01750	COG1335	isochorismatase
LM596_RS01770	COG0089	rRNA binding
LM596_RS01795	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LM596_RS01865	COG0563	adenylate kinase activity
LM596_RS01905	COG1122	ATPase activity
LM596_RS01930	COG0561	phosphatase activity
LM596_RS01955	COG3730	PTS system glucitol sorbitol-specific
LM596_RS01960	COG3732	PTS system glucitol sorbitol-specific
LM596_RS01990	COG0488	(ABC) transporter
LM596_RS02015	COG0436	Aminotransferase
LM596_RS02030	COG0583	DNA-binding transcription factor activity
LM596_RS02040	COG4684	Psort location CytoplasmicMembrane, score
LM596_RS02045	COG1705	Flagellar rod assembly protein muramidase FlgJ
LM596_RS02055	COG2233	PERMEase
LM596_RS02060	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LM596_RS02100	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LM596_RS02105	COG0765	amino acid transport
LM596_RS02110	COG1126	abc transporter atp-binding protein
LM596_RS02115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LM596_RS02120	COG0697	spore germination
LM596_RS02145	COG0366	Alpha amylase catalytic
LM596_RS02175	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LM596_RS02180	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LM596_RS02195	COG0583	DNA-binding transcription factor activity
LM596_RS02200	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LM596_RS02220	COG1619	proteins homologs of microcin C7 resistance protein MccF
LM596_RS02230	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LM596_RS02235	COG4166	transmembrane transport
LM596_RS02250	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LM596_RS02250	COG3711	transcriptional antiterminator
LM596_RS02255	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LM596_RS02255	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LM596_RS02255	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LM596_RS02260	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LM596_RS02260	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LM596_RS02260	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LM596_RS02265	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LM596_RS02270	COG0383	alpha-mannosidase activity
LM596_RS02280	COG0174	glutamine synthetase
LM596_RS02285	COG0531	amino acid
LM596_RS02305	COG2217	Heavy metal translocating P-type atpase
LM596_RS02315	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LM596_RS02320	COG4166	transmembrane transport
LM596_RS02330	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LM596_RS02340	COG0765	amino acid transport
LM596_RS02345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LM596_RS02350	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LM596_RS02360	COG0673	inositol 2-dehydrogenase activity
LM596_RS02365	COG0513	Belongs to the DEAD box helicase family
LM596_RS02375	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LM596_RS02385	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LM596_RS02400	COG0577	efflux transmembrane transporter activity
LM596_RS02420	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LM596_RS02425	COG0420	3'-5' exonuclease activity
LM596_RS02430	COG0419	ATPase involved in DNA repair
LM596_RS02470	COG3973	AAA domain
LM596_RS02480	COG0248	Ppx GppA phosphatase
LM596_RS02500	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LM596_RS02500	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LM596_RS02505	COG0084	hydrolase, TatD family'
LM596_RS02520	COG4466	Protein conserved in bacteria
LM596_RS02540	COG0436	Aminotransferase
LM596_RS02545	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LM596_RS02555	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LM596_RS02565	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LM596_RS02585	COG0363	glucosamine-6-phosphate deaminase activity
LM596_RS02590	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
LM596_RS02590	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
LM596_RS02625	COG1078	dGTPase activity
LM596_RS02645	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LM596_RS02650	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LM596_RS02655	COG0254	rRNA binding
LM596_RS02660	COG2252	PERMEase
LM596_RS02670	COG1704	LemA family
LM596_RS02685	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LM596_RS02710	COG2337	Toxic component of a toxin-antitoxin (TA) module
LM596_RS02730	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LM596_RS02740	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LM596_RS02750	COG1098	S1 RNA binding domain
LM596_RS02755	COG0037	tRNA processing
LM596_RS02760	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
LM596_RS02770	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LM596_RS02775	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LM596_RS02805	COG3104	oligopeptide transport
LM596_RS02820	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LM596_RS02830	COG2188	Transcriptional regulator
LM596_RS02840	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LM596_RS02850	COG2183	response to ionizing radiation
LM596_RS02855	COG3091	SprT-like family
LM596_RS02865	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LM596_RS02875	COG1316	TRANSCRIPTIONal
LM596_RS02885	COG0697	spore germination
LM596_RS02895	COG0588	phosphoglycerate mutase activity
LM596_RS02905	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LM596_RS02925	COG4956	integral membrane protein (PIN domain superfamily)
LM596_RS02940	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
LM596_RS02945	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LM596_RS02955	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LM596_RS02965	COG0250	Participates in transcription elongation, termination and antitermination
LM596_RS02985	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LM596_RS02995	COG0392	lysyltransferase activity
LM596_RS02995	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LM596_RS03000	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LM596_RS03005	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LM596_RS03010	COG1780	Probably involved in ribonucleotide reductase function
LM596_RS03015	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LM596_RS03020	COG2813	Specifically methylates the guanine in position
LM596_RS03025	COG0590	tRNA wobble adenosine to inosine editing
LM596_RS03035	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LM596_RS03040	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LM596_RS03055	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LM596_RS03060	COG3870	Protein conserved in bacteria
LM596_RS03065	COG0470	DNA polymerase III
LM596_RS03075	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LM596_RS03090	COG0406	alpha-ribazole phosphatase activity
LM596_RS03095	COG1809	phosphosulfolactate synthase activity
LM596_RS03105	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LM596_RS03110	COG1214	PFAM Peptidase M22, glycoprotease
LM596_RS03115	COG0456	acetyltransferase
LM596_RS03135	COG0488	(ABC) transporter
LM596_RS03145	COG1266	CAAX protease self-immunity
LM596_RS03150	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LM596_RS03160	COG0531	amino acid
LM596_RS03165	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LM596_RS03170	COG1739	Uncharacterized protein family UPF0029
LM596_RS03175	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
LM596_RS03180	COG1040	competence protein
LM596_RS03195	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LM596_RS03200	COG2884	Cell division ATP-binding protein ftsE
LM596_RS03205	COG2177	Part of the ABC transporter FtsEX involved in
LM596_RS03215	COG0745	RESPONSE REGULATOR receiver
LM596_RS03220	COG5002	protein histidine kinase activity
LM596_RS03225	COG0704	Plays a role in the regulation of phosphate uptake
LM596_RS03235	COG1950	PFAM Membrane protein of
LM596_RS03250	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LM596_RS03255	COG0492	ferredoxin-NADP+ reductase activity
LM596_RS03260	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LM596_RS03265	COG1827	regulation of RNA biosynthetic process
LM596_RS03270	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LM596_RS03275	COG0556	nucleotide-excision repair
LM596_RS03280	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LM596_RS03405	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
LM596_RS03420	COG0126	phosphoglycerate kinase activity
LM596_RS03435	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LM596_RS03440	COG0557	exoribonuclease II activity
LM596_RS03450	COG3584	3D domain protein
LM596_RS03450	COG1388	LysM domain
LM596_RS03455	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LM596_RS03470	COG0561	phosphatase activity
LM596_RS03475	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LM596_RS03480	COG0280	phosphate acetyltransferase
LM596_RS03485	COG0802	atpase or kinase
LM596_RS03510	COG1234	tRNA 3'-trailer cleavage
LM596_RS03515	COG1393	Belongs to the ArsC family
LM596_RS03520	COG4862	establishment of competence for transformation
LM596_RS03530	COG1164	Oligoendopeptidase f
LM596_RS03540	COG2357	RelA SpoT domain protein
LM596_RS03550	COG0564	pseudouridine synthase activity
LM596_RS03555	COG2239	Acts as a magnesium transporter
LM596_RS03560	COG2706	6-phosphogluconolactonase activity
LM596_RS03580	COG0500	methyltransferase
LM596_RS03590	COG1674	ftsk spoiiie
LM596_RS03595	COG0612	Peptidase, M16
LM596_RS03600	COG0612	Peptidase, M16
LM596_RS03610	COG1426	Protein conserved in bacteria
LM596_RS03615	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LM596_RS03620	COG1546	Belongs to the CinA family
LM596_RS03620	COG1058	Belongs to the CinA family
LM596_RS03625	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LM596_RS03635	COG1438	arginine binding
LM596_RS03640	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LM596_RS03655	COG4717	serine-type aminopeptidase activity
LM596_RS03660	COG3481	metal-dependent phosphohydrolase, HD sub domain
LM596_RS03670	COG0589	response to stress
LM596_RS03685	COG0531	amino acid
LM596_RS03705	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LM596_RS03710	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LM596_RS03715	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LM596_RS03720	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
LM596_RS03725	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LM596_RS03740	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LM596_RS03750	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LM596_RS03760	COG0151	Belongs to the GarS family
LM596_RS03765	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LM596_RS03770	COG0583	DNA-binding transcription factor activity
LM596_RS03775	COG0534	Mate efflux family protein
LM596_RS03795	COG1418	mRNA catabolic process
LM596_RS03800	COG1692	metallophosphoesterase
LM596_RS03825	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LM596_RS03830	COG0343	queuine tRNA-ribosyltransferase activity
LM596_RS03835	COG1862	Preprotein translocase
LM596_RS03840	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LM596_RS03845	COG1846	Transcriptional regulator
LM596_RS03850	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LM596_RS03855	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LM596_RS03860	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LM596_RS03865	COG1028	Short-chain dehydrogenase reductase Sdr
LM596_RS03870	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LM596_RS03885	COG0439	Biotin carboxylase
LM596_RS03895	COG0825	malonyl-CoA metabolic process
LM596_RS03900	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
LM596_RS03905	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LM596_RS03910	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LM596_RS03915	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
LM596_RS03920	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LM596_RS03925	COG0513	Belongs to the DEAD box helicase family
LM596_RS03935	COG1304	FMN binding
LM596_RS03950	COG2011	ABC-type metal ion transport system permease component
LM596_RS03960	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LM596_RS03985	COG3118	belongs to the thioredoxin family
LM596_RS04020	COG1696	Membrane protein involved in D-alanine export
LM596_RS04035	COG1719	4-vinyl reductase, 4VR
LM596_RS04040	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LM596_RS04090	COG0110	maltose O-acetyltransferase activity
LM596_RS04115	COG3201	nicotinamide mononucleotide transporter
LM596_RS04150	COG0626	cystathionine gamma-synthase activity
LM596_RS04155	COG0626	cystathionine gamma-synthase activity
LM596_RS04160	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
LM596_RS04165	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LM596_RS04170	COG0564	pseudouridine synthase activity
LM596_RS04180	COG2233	PERMEase
LM596_RS04195	COG0505	Belongs to the CarA family
LM596_RS04205	COG0167	dihydroorotate dehydrogenase activity
LM596_RS04225	COG2801	Transposase and inactivated derivatives
LM596_RS04250	COG2244	polysaccharide biosynthetic process
LM596_RS04255	COG0438	transferase activity, transferring glycosyl groups
LM596_RS04260	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LM596_RS04270	COG1088	dTDP-glucose 4,6-dehydratase activity
LM596_RS04275	COG1091	dTDP-4-dehydrorhamnose reductase activity
LM596_RS04320	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LM596_RS04325	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LM596_RS04330	COG3715	PTS system
LM596_RS04360	COG1227	inorganic diphosphatase activity
LM596_RS04380	COG1940	carbohydrate kinase activity
LM596_RS04385	COG2723	6-phospho-beta-galactosidase activity
LM596_RS04430	COG3684	Belongs to the aldolase LacD family
LM596_RS04440	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LM596_RS04445	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LM596_RS04445	COG1017	nitric oxide dioxygenase activity
LM596_RS04460	COG0745	RESPONSE REGULATOR receiver
LM596_RS04465	COG5002	protein histidine kinase activity
LM596_RS04475	COG0463	Glycosyl transferase, family 2
LM596_RS04480	COG0586	Pfam SNARE associated Golgi protein
LM596_RS04500	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LM596_RS04505	COG1268	BioY protein
LM596_RS04510	COG0436	Aminotransferase
LM596_RS04525	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LM596_RS04530	COG0765	amino acid transport
LM596_RS04535	COG1126	abc transporter atp-binding protein
LM596_RS04550	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LM596_RS04555	COG0436	Aminotransferase
LM596_RS04560	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LM596_RS04565	COG1028	Short-chain dehydrogenase reductase Sdr
LM596_RS04590	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LM596_RS04605	COG0438	transferase activity, transferring glycosyl groups
LM596_RS04625	COG0110	maltose O-acetyltransferase activity
LM596_RS04645	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LM596_RS04655	COG1088	dTDP-glucose 4,6-dehydratase activity
LM596_RS04660	COG1316	TRANSCRIPTIONal
LM596_RS04670	COG0489	protein tyrosine kinase activity
LM596_RS04675	COG4464	protein tyrosine phosphatase activity
LM596_RS04695	COG0463	Glycosyl transferase, family 2
LM596_RS04710	COG3706	GGDEF domain
LM596_RS04720	COG2199	diguanylate cyclase activity
LM596_RS04745	COG0531	amino acid
LM596_RS04750	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
LM596_RS04755	COG0402	S-adenosylhomocysteine deaminase activity
LM596_RS04760	COG0604	alcohol dehydrogenase
LM596_RS04770	COG4720	Psort location CytoplasmicMembrane, score
LM596_RS04775	COG1122	ATPase activity
LM596_RS04785	COG1611	Belongs to the LOG family
LM596_RS04795	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LM596_RS04805	COG3425	synthase
LM596_RS04825	COG0248	Ppx GppA phosphatase
LM596_RS04830	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LM596_RS04845	COG2818	Glycosylase
LM596_RS04850	COG0589	response to stress
LM596_RS04865	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LM596_RS04870	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LM596_RS04875	COG1956	GAF domain-containing protein
LM596_RS04880	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
LM596_RS04890	COG1104	cysteine desulfurase activity
LM596_RS04900	COG0525	valine-tRNA ligase activity
LM596_RS04915	COG0285	dihydrofolate synthase activity
LM596_RS04920	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LM596_RS04925	COG2003	Belongs to the UPF0758 family
LM596_RS04935	COG1077	Cell shape determining protein MreB Mrl
LM596_RS04940	COG1792	Involved in formation and maintenance of cell shape
LM596_RS04950	COG0850	regulation of cytokinetic process
LM596_RS04955	COG2894	cell division
LM596_RS04960	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LM596_RS04985	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LM596_RS04990	COG1942	4-Oxalocrotonate Tautomerase
LM596_RS04995	COG0019	diaminopimelate decarboxylase activity
LM596_RS05000	COG0671	phosphoesterase, PA-phosphatase related
LM596_RS05005	COG0561	phosphatase activity
LM596_RS05010	COG1073	alpha beta
LM596_RS05015	COG2151	metal-sulfur cluster biosynthetic enzyme
LM596_RS05025	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
LM596_RS05025	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LM596_RS05030	COG1063	alcohol dehydrogenase
LM596_RS05060	COG1199	ATP-dependent helicase activity
LM596_RS05060	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LM596_RS05080	COG3935	DnaD domain protein
LM596_RS05085	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LM596_RS05090	COG0706	membrane insertase activity
LM596_RS05100	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LM596_RS05110	COG1733	regulation of RNA biosynthetic process
LM596_RS05120	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LM596_RS05120	COG0072	phenylalanine-tRNA ligase activity
LM596_RS05125	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LM596_RS05135	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LM596_RS05145	COG0778	Nitroreductase
LM596_RS05170	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LM596_RS05250	COG0863	Belongs to the N(4) N(6)-methyltransferase family
LM596_RS05255	COG3620	sequence-specific DNA binding
LM596_RS05380	COG3953	SLT domain
LM596_RS05380	COG5412	phage tail tape measure protein
LM596_RS05415	COG3942	CHAP domain
LM596_RS05415	COG1388	LysM domain
LM596_RS05430	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LM596_RS05485	COG2801	Transposase and inactivated derivatives
LM596_RS05560	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LM596_RS05565	COG0463	Glycosyl transferase, family 2
LM596_RS05575	COG0671	phosphoesterase, PA-phosphatase related
LM596_RS05590	COG0628	permease
LM596_RS05630	COG0351	phosphomethylpyrimidine kinase
LM596_RS05640	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LM596_RS05645	COG3142	Participates in the control of copper homeostasis
LM596_RS05650	COG0105	UTP biosynthetic process
LM596_RS05680	COG4166	transmembrane transport
LM596_RS05685	COG0601	transmembrane transport
LM596_RS05690	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LM596_RS05695	COG0444	Belongs to the ABC transporter superfamily
LM596_RS05710	COG4690	dipeptidase activity
LM596_RS05720	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LM596_RS05735	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
LM596_RS05740	COG0477	Major facilitator Superfamily
LM596_RS05790	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LM596_RS05815	COG1846	Transcriptional regulator
LM596_RS05820	COG2249	NAD(P)H dehydrogenase (quinone) activity
LM596_RS05840	COG1309	transcriptional regulator
LM596_RS05850	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LM596_RS05885	COG1131	(ABC) transporter
LM596_RS05895	COG0702	epimerase
LM596_RS05910	COG0477	Major facilitator Superfamily
LM596_RS05920	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
LM596_RS05925	COG1683	Conserved Protein
LM596_RS05930	COG0477	Major facilitator Superfamily
LM596_RS05955	COG2076	Multidrug Resistance protein
LM596_RS05970	COG2814	Major facilitator Superfamily
LM596_RS05985	COG0531	amino acid
LM596_RS06000	COG2226	methyltransferase
LM596_RS06010	COG3760	aminoacyl-tRNA metabolism involved in translational fidelity
LM596_RS06020	COG0583	DNA-binding transcription factor activity
LM596_RS06050	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LM596_RS06055	COG0789	Transcriptional regulator
LM596_RS06060	COG0656	L-ascorbic acid biosynthetic process
LM596_RS06080	COG2826	transposase and inactivated derivatives, IS30 family
LM596_RS06115	COG1293	RNA-binding protein homologous to eukaryotic snRNP
LM596_RS06125	COG0583	DNA-binding transcription factor activity
LM596_RS06130	COG0163	prenyltransferase activity
LM596_RS06135	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
LM596_RS06140	COG2814	Major facilitator Superfamily
LM596_RS06155	COG1028	Short-chain dehydrogenase reductase Sdr
LM596_RS06160	COG1116	anion transmembrane transporter activity
LM596_RS06165	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LM596_RS06170	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LM596_RS06185	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LM596_RS06190	COG0187	DNA topoisomerase II activity
LM596_RS06210	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
LM596_RS06215	COG4974	Belongs to the 'phage' integrase family
LM596_RS06220	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LM596_RS06225	COG0758	DNA mediated transformation
LM596_RS06230	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LM596_RS06235	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LM596_RS06240	COG0681	Belongs to the peptidase S26 family
LM596_RS06245	COG0793	Belongs to the peptidase S41A family
LM596_RS06245	COG3409	Peptidoglycan-binding domain 1 protein
LM596_RS06260	COG2755	lipolytic protein G-D-S-L family
LM596_RS06275	COG0488	(ABC) transporter
LM596_RS06290	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LM596_RS06295	COG0457	Tetratricopeptide repeat
LM596_RS06310	COG0539	negative regulation of cytoplasmic translation
LM596_RS06325	COG0514	ATP-dependent DNA helicase (RecQ)
LM596_RS06335	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LM596_RS06340	COG1187	pseudouridine synthase activity
LM596_RS06365	COG0735	belongs to the Fur family
LM596_RS06370	COG2996	Protein conserved in bacteria
LM596_RS06390	COG0587	DNA-directed DNA polymerase activity
LM596_RS06400	COG0542	response to heat
LM596_RS06410	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LM596_RS06415	COG2384	SAM-dependent methyltransferase
LM596_RS06430	COG0626	cystathionine gamma-synthase activity
LM596_RS06435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LM596_RS06440	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LM596_RS06445	COG0358	DNA primase activity
LM596_RS06470	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LM596_RS06480	COG1702	phosphate starvation-inducible protein PhoH
LM596_RS06485	COG1610	YqeY-like protein
LM596_RS06500	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
LM596_RS06525	COG0860	N-Acetylmuramoyl-L-alanine amidase
LM596_RS06540	COG1490	D-aminoacyl-tRNA deacylase activity
LM596_RS06545	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LM596_RS06555	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LM596_RS06560	COG2264	protein methyltransferase activity
LM596_RS06595	COG0443	Heat shock 70 kDa protein
LM596_RS06610	COG0196	riboflavin kinase activity
LM596_RS06620	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LM596_RS06635	COG2740	Nucleic-acid-binding protein implicated in transcription termination
LM596_RS06640	COG0195	Participates in both transcription termination and antitermination
LM596_RS06660	COG0750	zinc metalloprotease
LM596_RS06665	COG4589	Belongs to the CDS family
LM596_RS06670	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LM596_RS06680	COG0528	UMP kinase activity
LM596_RS06695	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LM596_RS06700	COG2827	Endonuclease containing a URI domain
LM596_RS06705	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
LM596_RS06710	COG0204	Acyl-transferase
LM596_RS06720	COG4224	UPF0291 protein
LM596_RS06725	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LM596_RS06730	COG0497	DNA recombination
LM596_RS06735	COG1438	arginine binding
LM596_RS06740	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
LM596_RS06750	COG1722	exodeoxyribonuclease VII activity
LM596_RS06755	COG1570	exodeoxyribonuclease VII activity
LM596_RS06765	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LM596_RS06770	COG1302	Protein conserved in bacteria
LM596_RS06775	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LM596_RS06785	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LM596_RS06790	COG2868	ribosomal protein
LM596_RS06795	COG0261	This protein binds to 23S rRNA in the presence of protein L20
LM596_RS06840	COG0385	Bile acid
LM596_RS06850	COG4166	transmembrane transport
LM596_RS06870	COG0333	Belongs to the bacterial ribosomal protein bL32 family
LM596_RS06875	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LM596_RS06890	COG0822	iron-sulfur transferase activity
LM596_RS06895	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LM596_RS06900	COG0719	Fe-S assembly protein
LM596_RS06910	COG1393	Belongs to the ArsC family
LM596_RS06915	COG0772	Belongs to the SEDS family
LM596_RS06925	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
LM596_RS06930	COG1077	Cell shape determining protein MreB Mrl
LM596_RS06935	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LM596_RS06940	COG4836	Membrane
LM596_RS06975	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LM596_RS06980	COG0356	it plays a direct role in the translocation of protons across the membrane
LM596_RS06990	COG0009	L-threonylcarbamoyladenylate synthase
LM596_RS06995	COG2890	protein-(glutamine-N5) methyltransferase activity
LM596_RS07005	COG1435	thymidine kinase activity
LM596_RS07010	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LM596_RS07015	COG3442	glutamine amidotransferase
LM596_RS07020	COG1482	cell wall glycoprotein biosynthetic process
LM596_RS07025	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LM596_RS07030	COG0406	alpha-ribazole phosphatase activity
LM596_RS07050	COG1011	Hydrolase
LM596_RS07080	COG0328	RNA-DNA hybrid ribonuclease activity
LM596_RS07085	COG0116	Belongs to the methyltransferase superfamily
LM596_RS07095	COG3599	regulation of cell shape
LM596_RS07100	COG4474	Belongs to the UPF0398 family
LM596_RS07110	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LM596_RS07115	COG1266	CAAX protease self-immunity
LM596_RS07125	COG3764	Sortase (surface protein transpeptidase)
LM596_RS07130	COG5002	protein histidine kinase activity
LM596_RS07135	COG0745	RESPONSE REGULATOR receiver
LM596_RS07140	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LM596_RS07175	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LM596_RS07190	COG1466	dna polymerase III delta subunit
LM596_RS07195	COG2333	competence protein COMEC
LM596_RS07195	COG0658	competence protein
LM596_RS07200	COG2131	deaminase
LM596_RS07205	COG1555	photosystem II stabilization
LM596_RS07205	COG1596	polysaccharide export
LM596_RS07210	COG3759	membrane
LM596_RS07215	COG3480	Lon protease (S16) C-terminal proteolytic domain
LM596_RS07220	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LM596_RS07225	COG0742	ribosomal rna small subunit methyltransferase
LM596_RS07240	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LM596_RS07250	COG4838	Belongs to the UPF0358 family
LM596_RS07255	COG1217	gtp-binding protein TYPA
LM596_RS07260	COG0483	inositol monophosphate 1-phosphatase activity
LM596_RS07280	COG5503	Protein of unknown function (DUF1447)
LM596_RS07295	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LM596_RS07320	COG1104	cysteine desulfurase activity
LM596_RS07350	COG3599	regulation of cell shape
LM596_RS07355	COG2302	S4 RNA-binding domain
LM596_RS07360	COG0762	integral membrane protein
LM596_RS07365	COG1799	cell septum assembly
LM596_RS07400	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LM596_RS07405	COG0768	penicillin binding
LM596_RS07420	COG2001	Belongs to the MraZ family
LM596_RS07430	COG0527	aspartate kinase activity
LM596_RS07475	COG4942	peptidase
LM596_RS07580	COG1783	phage Terminase large subunit
LM596_RS07585	COG3728	DNA packaging
LM596_RS07585	COG5484	DNA packaging
LM596_RS07615	COG3620	sequence-specific DNA binding
LM596_RS07625	COG0863	Belongs to the N(4) N(6)-methyltransferase family
LM596_RS07645	COG3723	Recombinational DNA repair protein, rece pathway
LM596_RS07690	COG1396	sequence-specific DNA binding
LM596_RS07705	COG1192	Involved in chromosome partitioning
LM596_RS07720	COG0582	viral genome integration into host DNA
LM596_RS07745	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LM596_RS07755	COG0552	protein localization to endoplasmic reticulum
LM596_RS07760	COG1196	nuclear chromosome segregation
LM596_RS07770	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LM596_RS07780	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LM596_RS07785	COG1461	Dihydroxyacetone kinase
LM596_RS07800	COG1564	THIamine pyrophosphokinase
LM596_RS07805	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LM596_RS07810	COG1162	GTPase activity
LM596_RS07815	COG2815	serine threonine protein kinase
LM596_RS07815	COG0515	serine threonine protein kinase
LM596_RS07820	COG0631	protein serine/threonine phosphatase activity
LM596_RS07825	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LM596_RS07825	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LM596_RS07835	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LM596_RS07840	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LM596_RS07845	COG1758	RNA polymerase activity
LM596_RS07865	COG0789	Transcriptional regulator
LM596_RS07870	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
LM596_RS07875	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LM596_RS07885	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LM596_RS07890	COG1940	carbohydrate kinase activity
LM596_RS07900	COG0457	Tetratricopeptide repeat
LM596_RS07900	COG0705	Rhomboid family
LM596_RS07905	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LM596_RS07910	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LM596_RS07915	COG0768	penicillin binding
LM596_RS07925	COG0569	domain protein
LM596_RS07935	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LM596_RS07935	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
LM596_RS07945	COG0300	oxidoreductase activity
LM596_RS07960	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
LM596_RS07960	COG2755	lipolytic protein G-D-S-L family
LM596_RS07970	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LM596_RS07980	COG1126	abc transporter atp-binding protein
LM596_RS07985	COG0765	amino acid transport
LM596_RS08020	COG2226	methyltransferase
LM596_RS08025	COG0799	negative regulation of ribosome biogenesis
LM596_RS08030	COG1713	HD superfamily hydrolase involved in NAD metabolism
LM596_RS08035	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LM596_RS08040	COG1534	Rna-binding protein
LM596_RS08045	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LM596_RS08050	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
LM596_RS08065	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LM596_RS08075	COG1484	DNA-dependent DNA replication
LM596_RS08085	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LM596_RS08090	COG0237	dephospho-CoA kinase activity
LM596_RS08100	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LM596_RS08100	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LM596_RS08105	COG0670	Belongs to the BI1 family
LM596_RS08120	COG1674	ftsk spoiiie
LM596_RS08125	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LM596_RS08130	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LM596_RS08150	COG4473	ABC transporter
LM596_RS08155	COG1131	(ABC) transporter
LM596_RS08160	COG0537	adenosine 5'-monophosphoramidase activity
LM596_RS08200	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LM596_RS08205	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LM596_RS08210	COG1187	pseudouridine synthase activity
LM596_RS08215	COG2244	polysaccharide biosynthetic process
LM596_RS08340	COG1098	S1 RNA binding domain
LM596_RS08355	COG0586	Pfam SNARE associated Golgi protein
LM596_RS08365	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LM596_RS08370	COG0436	Aminotransferase
LM596_RS08380	COG0436	Aminotransferase
LM596_RS08385	COG1473	amidohydrolase
LM596_RS08415	COG0626	cystathionine gamma-synthase activity
LM596_RS08425	COG0647	UMP catabolic process
LM596_RS08430	COG4470	Protein conserved in bacteria
LM596_RS08435	COG0737	Belongs to the 5'-nucleotidase family
LM596_RS08445	COG0827	DNA restriction-modification system
LM596_RS08505	COG5412	phage tail tape measure protein
LM596_RS08505	COG3953	SLT domain
LM596_RS08605	COG3620	sequence-specific DNA binding
LM596_RS08610	COG0863	Belongs to the N(4) N(6)-methyltransferase family
LM596_RS08640	COG0629	single-stranded DNA binding
LM596_RS08705	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LM596_RS08725	COG1609	Transcriptional regulator
LM596_RS08730	COG0006	proline dipeptidase activity
LM596_RS08740	COG2801	Transposase and inactivated derivatives
LM596_RS08755	COG0668	transmembrane transport
LM596_RS08775	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LM596_RS08780	COG0673	inositol 2-dehydrogenase activity
LM596_RS08785	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LM596_RS08790	COG0140	phosphoribosyl-ATP diphosphatase activity
LM596_RS08795	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LM596_RS08800	COG0107	imidazoleglycerol-phosphate synthase activity
LM596_RS08805	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LM596_RS08810	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LM596_RS08815	COG0131	Imidazoleglycerol-phosphate dehydratase
LM596_RS08820	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LM596_RS08825	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
LM596_RS08830	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
LM596_RS08835	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LM596_RS08850	COG4975	Glucose uptake
LM596_RS08855	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LM596_RS08860	COG1368	sulfuric ester hydrolase activity
LM596_RS08865	COG5002	protein histidine kinase activity
LM596_RS08865	COG3850	Histidine kinase
LM596_RS08870	COG0745	RESPONSE REGULATOR receiver
LM596_RS08900	COG0328	RNA-DNA hybrid ribonuclease activity
LM596_RS08905	COG1272	protein, Hemolysin III
LM596_RS08935	COG0704	Plays a role in the regulation of phosphate uptake
LM596_RS08940	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LM596_RS08950	COG0581	inorganic phosphate transmembrane transporter activity
LM596_RS08955	COG0573	inorganic phosphate transmembrane transporter activity
LM596_RS08990	COG0025	NhaP-type Na H and K H
LM596_RS08995	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LM596_RS09000	COG2176	DNA-directed DNA polymerase activity
LM596_RS09005	COG0004	ammonium transporteR
LM596_RS09095	COG1368	sulfuric ester hydrolase activity
LM596_RS09110	COG0438	transferase activity, transferring glycosyl groups
LM596_RS09115	COG0438	transferase activity, transferring glycosyl groups
LM596_RS09120	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LM596_RS09125	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LM596_RS09135	COG0542	response to heat
LM596_RS09155	COG4535	Mg2 and Co2 transporter CorC
LM596_RS09160	COG1134	teichoic acid transport
LM596_RS09165	COG0628	permease
LM596_RS09175	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LM596_RS09180	COG2137	regulation of response to DNA damage stimulus
LM596_RS09190	COG1388	LysM domain
LM596_RS09190	COG3942	CHAP domain
LM596_RS09200	COG0024	Methionine aminopeptidase
LM596_RS09205	COG0716	FMN binding
LM596_RS09215	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LM596_RS09220	COG4493	Belongs to the UPF0637 family
LM596_RS09225	COG1132	(ABC) transporter
LM596_RS09230	COG1132	(ABC) transporter
LM596_RS09245	COG2610	gluconate transmembrane transporter activity
LM596_RS09250	COG1929	Belongs to the glycerate kinase type-1 family
LM596_RS09255	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LM596_RS09260	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LM596_RS09265	COG1012	belongs to the aldehyde dehydrogenase family
LM596_RS09270	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LM596_RS09275	COG1126	abc transporter atp-binding protein
LM596_RS09280	COG0765	amino acid transport
LM596_RS09285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LM596_RS09295	COG4187	Peptidase family M20/M25/M40
LM596_RS09300	COG2246	polysaccharide biosynthetic process
LM596_RS09330	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
LM596_RS09340	COG0028	Belongs to the TPP enzyme family
LM596_RS09345	COG1132	(ABC) transporter
LM596_RS09350	COG1132	(ABC) transporter
LM596_RS09360	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LM596_RS09370	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LM596_RS09375	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LM596_RS09380	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
LM596_RS09385	COG0436	Aminotransferase
LM596_RS09390	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LM596_RS09400	COG0402	S-adenosylhomocysteine deaminase activity
LM596_RS09405	COG0025	NhaP-type Na H and K H
LM596_RS09420	COG1027	Aspartate ammonia-lyase
LM596_RS09430	COG1216	Glycosyl transferase, family 2
LM596_RS09440	COG0438	transferase activity, transferring glycosyl groups
LM596_RS09445	COG1131	(ABC) transporter
LM596_RS09455	COG0477	Major facilitator Superfamily
LM596_RS09480	COG2962	Rard protein
LM596_RS09490	COG1177	transmembrane transport
LM596_RS09495	COG1176	ABC-type spermidine putrescine transport system, permease component I
LM596_RS09500	COG3842	ATPase activity
LM596_RS09515	COG0242	peptide deformylase activity
LM596_RS09530	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LM596_RS09535	COG0737	Belongs to the 5'-nucleotidase family
LM596_RS09540	COG1737	Transcriptional regulator
LM596_RS09550	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LM596_RS09555	COG0673	inositol 2-dehydrogenase activity
LM596_RS09560	COG0446	pyridine nucleotide-disulphide oxidoreductase
LM596_RS09565	COG1053	succinate dehydrogenase
LM596_RS09565	COG3976	FMN-binding domain protein
LM596_RS09565	COG0431	NADPH-dependent FMN reductase
LM596_RS09585	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LM596_RS09605	COG0531	amino acid
LM596_RS09610	COG2814	Major facilitator Superfamily
LM596_RS09615	COG0066	3-isopropylmalate dehydratase activity
LM596_RS09620	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LM596_RS09625	COG0473	3-isopropylmalate dehydrogenase activity
LM596_RS09630	COG0133	tryptophan synthase activity
LM596_RS09635	COG0765	amino acid transport
LM596_RS09640	COG1126	abc transporter atp-binding protein
LM596_RS09660	COG2723	6-phospho-beta-galactosidase activity
LM596_RS09665	COG2723	6-phospho-beta-galactosidase activity
LM596_RS09670	COG1263	PTS System
LM596_RS09670	COG2190	(PTS) system
LM596_RS09670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LM596_RS09675	COG3711	transcriptional antiterminator
LM596_RS09680	COG0159	tryptophan synthase activity
LM596_RS09690	COG0135	phosphoribosylanthranilate isomerase activity
LM596_RS09695	COG0134	indole-3-glycerol-phosphate synthase activity
LM596_RS09705	COG0512	Glutamine amidotransferase of anthranilate synthase
LM596_RS09715	COG2040	homocysteine
LM596_RS09720	COG0833	amino acid
LM596_RS09725	COG0538	isocitrate dehydrogenase activity
LM596_RS09730	COG0372	Belongs to the citrate synthase family
LM596_RS09735	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LM596_RS09740	COG1120	ATPase activity
LM596_RS09745	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LM596_RS09775	COG1132	(ABC) transporter
LM596_RS09790	COG2873	o-acetylhomoserine
LM596_RS09795	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LM596_RS09830	COG2357	RelA SpoT domain protein
LM596_RS09855	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
LM596_RS09865	COG0277	FAD linked oxidase domain protein
LM596_RS09870	COG0583	DNA-binding transcription factor activity
LM596_RS09875	COG2323	membrane
LM596_RS09885	COG0840	transmembrane signaling receptor activity
LM596_RS09890	COG1215	transferase activity, transferring glycosyl groups
LM596_RS09895	COG1940	carbohydrate kinase activity
LM596_RS09920	COG1012	belongs to the aldehyde dehydrogenase family
LM596_RS09920	COG1454	alcohol dehydrogenase
LM596_RS09940	COG2197	response regulator
LM596_RS09945	COG4585	Histidine kinase
LM596_RS09950	COG2409	Drug exporters of the RND superfamily
LM596_RS09965	COG3716	PTS system mannose fructose sorbose family IID component
LM596_RS09970	COG3715	PTS system
LM596_RS09975	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LM596_RS09980	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LM596_RS10000	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
LM596_RS10005	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
LM596_RS10010	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LM596_RS10015	COG2807	transmembrane transport
LM596_RS10020	COG3973	AAA domain
LM596_RS10050	COG1309	transcriptional regulator
LM596_RS10070	COG0300	oxidoreductase activity
LM596_RS10075	COG1309	transcriptional regulator
LM596_RS10085	COG1942	4-Oxalocrotonate Tautomerase
LM596_RS10100	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LM596_RS10105	COG1733	regulation of RNA biosynthetic process
LM596_RS10155	COG2801	Transposase and inactivated derivatives
LM596_RS10160	COG0508	dehydrogenase complex catalyzes the overall conversion of
LM596_RS10165	COG0022	dehydrogenase e1 component
LM596_RS10170	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LM596_RS10175	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LM596_RS10180	COG3284	Transcriptional regulator
LM596_RS10190	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LM596_RS10200	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LM596_RS10215	COG1621	beta-fructofuranosidase activity
LM596_RS10220	COG0656	L-ascorbic acid biosynthetic process
LM596_RS10235	COG1012	belongs to the aldehyde dehydrogenase family
LM596_RS10260	COG1122	ATPase activity
LM596_RS10270	COG0588	phosphoglycerate mutase activity
LM596_RS10275	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
LM596_RS10280	COG0628	permease
LM596_RS10295	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LM596_RS10300	COG2188	Transcriptional regulator
LM596_RS10315	COG0586	Pfam SNARE associated Golgi protein
LM596_RS10325	COG0095	Lipoate-protein ligase
LM596_RS10345	COG2814	Major facilitator Superfamily
LM596_RS10355	COG0604	alcohol dehydrogenase
LM596_RS10360	COG1028	Short-chain dehydrogenase reductase Sdr
LM596_RS10365	COG0604	alcohol dehydrogenase
LM596_RS10370	COG1733	regulation of RNA biosynthetic process
LM596_RS10375	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LM596_RS10380	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LM596_RS10390	COG4721	ABC-type cobalt transport system, permease component
LM596_RS10395	COG4172	Belongs to the ABC transporter superfamily
LM596_RS10405	COG2855	membrane
LM596_RS10410	COG0583	DNA-binding transcription factor activity
LM596_RS10430	COG1228	amidohydrolase
LM596_RS10450	COG1116	anion transmembrane transporter activity
LM596_RS10465	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LM596_RS10525	COG0129	dihydroxy-acid dehydratase activity
LM596_RS10530	COG0251	oxidation-reduction process
LM596_RS10535	COG1119	ATPase activity
LM596_RS10540	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LM596_RS10545	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LM596_RS10550	COG0028	Belongs to the TPP enzyme family
LM596_RS10560	COG0477	Major facilitator Superfamily
LM596_RS10565	COG1511	domain protein
LM596_RS10565	COG1511	domain protein
LM596_RS10570	COG1686	Belongs to the peptidase S11 family
LM596_RS10585	COG3527	Alpha-acetolactate decarboxylase
LM596_RS10600	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LM596_RS10605	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LM596_RS10610	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LM596_RS10615	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LM596_RS10620	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LM596_RS10625	COG0277	FAD linked oxidase domain protein
LM596_RS10635	COG2270	Major facilitator Superfamily
LM596_RS10640	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
LM596_RS10665	COG1914	H( )-stimulated, divalent metal cation uptake system
LM596_RS10670	COG0604	alcohol dehydrogenase
LM596_RS10675	COG1573	uracil-dna glycosylase
LM596_RS10680	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LM596_RS10685	COG3842	ATPase activity
LM596_RS10690	COG0395	ABC-type sugar transport system, permease component
LM596_RS10695	COG1175	transmembrane transport
LM596_RS10710	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LM596_RS10715	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
LM596_RS10720	COG1461	Dihydroxyacetone kinase
LM596_RS10725	COG2376	Dihydroxyacetone kinase
LM596_RS10735	COG1175	transmembrane transport
LM596_RS10750	COG2226	methyltransferase
LM596_RS10755	COG1304	FMN binding
LM596_RS10760	COG4166	transmembrane transport
LM596_RS10765	COG0393	Putative heavy-metal-binding
LM596_RS10775	COG0517	IMP dehydrogenase activity
LM596_RS10775	COG0516	GMP reductase activity
LM596_RS10780	COG0477	Major facilitator Superfamily
LM596_RS10810	COG0494	nUDIX hydrolase
LM596_RS10860	COG1215	transferase activity, transferring glycosyl groups
LM596_RS10865	COG1705	Flagellar rod assembly protein muramidase FlgJ
LM596_RS10885	COG2814	Major facilitator Superfamily
LM596_RS10890	COG0673	inositol 2-dehydrogenase activity
LM596_RS10895	COG0673	inositol 2-dehydrogenase activity
LM596_RS10900	COG0673	inositol 2-dehydrogenase activity
LM596_RS10905	COG4975	Glucose uptake
LM596_RS10915	COG2096	Adenosyltransferase
LM596_RS10920	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LM596_RS10935	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LM596_RS10945	COG2814	Major facilitator Superfamily
LM596_RS10955	COG0012	GTP binding
LM596_RS10960	COG4481	Protein conserved in bacteria
LM596_RS10965	COG1475	DNA binding
LM596_RS10970	COG1192	Involved in chromosome partitioning
LM596_RS10975	COG1475	DNA binding
LM596_RS10980	COG0357	Ribosomal RNA small subunit methyltransferase G
LM596_RS10995	COG1516	flagellar protein fliS
LM596_RS11005	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
LM596_RS11010	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LM596_RS11035	COG0235	Class ii aldolase
LM596_RS11040	COG4806	L-rhamnose isomerase
LM596_RS11055	COG2814	Major facilitator Superfamily
LM596_RS11075	COG4786	Flagellar basal body rod
LM596_RS11075	COG1256	bacterial-type flagellum assembly
LM596_RS11090	COG1776	CheC inhibitor of MCP methylation
LM596_RS11090	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LM596_RS11105	COG2201	protein-glutamate methylesterase activity
LM596_RS11110	COG1776	CheC inhibitor of MCP methylation
LM596_RS11115	COG2198	Histidine kinase
LM596_RS11115	COG0643	Histidine kinase
LM596_RS11120	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
LM596_RS11125	COG2201	protein-glutamate methylesterase activity
LM596_RS11140	COG0840	transmembrane signaling receptor activity
LM596_RS11145	COG2884	Cell division ATP-binding protein ftsE
LM596_RS11150	COG4786	Flagellar basal body rod
LM596_RS11155	COG4786	Flagellar basal body rod
LM596_RS11160	COG1191	sigma factor activity
LM596_RS11165	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LM596_RS11170	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LM596_RS11175	COG1684	flagellar biosynthetic protein fliR
LM596_RS11180	COG1987	bacterial-type flagellum assembly
LM596_RS11185	COG1338	Plays a role in the flagellum-specific transport system
LM596_RS11205	COG4786	Flagellar basal body rod
LM596_RS11230	COG1157	protein secretion by the type III secretion system
LM596_RS11240	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LM596_RS11250	COG1677	Flagellar hook-basal body complex protein FliE
LM596_RS11260	COG1815	bacterial-type flagellum-dependent cell motility
LM596_RS11265	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LM596_RS11270	COG1360	Flagellar Motor Protein
LM596_RS11280	COG0840	transmembrane signaling receptor activity
LM596_RS11305	COG1957	nucleoside hydrolase
LM596_RS11315	COG0438	transferase activity, transferring glycosyl groups
LM596_RS11320	COG1418	mRNA catabolic process
LM596_RS11330	COG1120	ATPase activity
LM596_RS11335	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LM596_RS11345	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LM596_RS11350	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LM596_RS11365	COG3547	Transposase (IS116 IS110 IS902 family)
LM596_RS11395	COG3716	PTS system mannose fructose sorbose family IID component
LM596_RS11400	COG3715	PTS system
LM596_RS11410	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LM596_RS11410	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LM596_RS11415	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
LM596_RS11415	COG3933	PFAM sigma-54 factor interaction domain-containing protein
LM596_RS11420	COG4166	transmembrane transport
LM596_RS11430	COG2223	nitrite transmembrane transporter activity
LM596_RS11440	COG2084	Dehydrogenase
LM596_RS11445	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LM596_RS11510	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LM596_RS11515	COG4988	ABC transporter
LM596_RS11520	COG1294	oxidase, subunit
LM596_RS11525	COG1271	oxidase subunit
LM596_RS11530	COG0438	transferase activity, transferring glycosyl groups
LM596_RS11535	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LM596_RS11545	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LM596_RS11550	COG3711	transcriptional antiterminator
LM596_RS11555	COG2213	PTS system mannitol-specific
LM596_RS11570	COG2188	Transcriptional regulator
LM596_RS11575	COG0366	Alpha amylase catalytic
LM596_RS11580	COG1968	undecaprenyl-diphosphatase activity
LM596_RS11595	COG0698	ribose 5-phosphate isomerase
LM596_RS11600	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LM596_RS11605	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LM596_RS11615	COG1011	Hydrolase
LM596_RS11625	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LM596_RS11635	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LM596_RS11635	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LM596_RS11635	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LM596_RS11645	COG0493	'glutamate synthase
LM596_RS11650	COG0070	glutamate synthase
LM596_RS11650	COG0069	glutamate synthase activity
LM596_RS11650	COG0067	glutamate synthase
LM596_RS11655	COG1079	Belongs to the binding-protein-dependent transport system permease family
LM596_RS11660	COG4603	Belongs to the binding-protein-dependent transport system permease family
LM596_RS11665	COG3845	ABC transporter
LM596_RS11670	COG1744	ABC transporter substrate-binding protein PnrA-like
LM596_RS11675	COG1957	nucleoside hydrolase
LM596_RS11680	COG0640	Transcriptional regulator
LM596_RS11685	COG3684	Belongs to the aldolase LacD family
LM596_RS11690	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LM596_RS11690	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LM596_RS11690	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LM596_RS11715	COG1733	regulation of RNA biosynthetic process
LM596_RS11735	COG2801	Transposase and inactivated derivatives
LM596_RS11850	COG0791	NLP P60 protein
LM596_RS11850	COG0741	lytic transglycosylase activity
LM596_RS11855	COG5644	endopeptidase inhibitor activity
LM596_RS11870	COG0433	COG0433 Predicted ATPase
LM596_RS11905	COG1132	(ABC) transporter
LM596_RS11940	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LM596_RS11940	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LM596_RS11940	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LM596_RS11975	COG1247	-acetyltransferase
LM596_RS11980	COG1309	transcriptional regulator
LM596_RS11990	COG4978	Transcriptional regulator
LM596_RS11990	COG0789	Transcriptional regulator
LM596_RS12000	COG0446	pyridine nucleotide-disulphide oxidoreductase
LM596_RS12015	COG0366	Alpha amylase catalytic
LM596_RS12015	COG5263	repeat protein
LM596_RS12030	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LM596_RS12035	COG1780	Probably involved in ribonucleotide reductase function
LM596_RS12040	COG0318	PFAM AMP-dependent synthetase and ligase
LM596_RS12045	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LM596_RS12050	COG2050	protein possibly involved in aromatic compounds catabolism
LM596_RS12065	COG0789	Transcriptional regulator
LM596_RS12070	COG3275	phosphorelay sensor kinase activity
LM596_RS12080	COG2814	Major facilitator Superfamily
LM596_RS12095	COG1380	Effector of murein hydrolase LrgA
LM596_RS12100	COG1346	cytolysis
LM596_RS12105	COG1846	Transcriptional regulator
LM596_RS12110	COG0656	L-ascorbic acid biosynthetic process
LM596_RS12115	COG3590	peptidase
LM596_RS12120	COG1846	Transcriptional regulator
LM596_RS12125	COG0477	Major facilitator Superfamily
LM596_RS12130	COG0706	membrane insertase activity
LM596_RS12165	COG2261	transglycosylase associated protein
LM596_RS12185	COG0281	malic enzyme
LM596_RS12195	COG2801	Transposase and inactivated derivatives
LM596_RS12225	COG3421	Type III restriction
LM596_RS12230	COG2189	Belongs to the N(4) N(6)-methyltransferase family
LM596_RS12255	COG1028	Short-chain dehydrogenase reductase Sdr
LM596_RS12260	COG0438	transferase activity, transferring glycosyl groups
LM596_RS12270	COG1192	Involved in chromosome partitioning
LM596_RS12280	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LM596_RS12320	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LM596_RS12360	COG2151	metal-sulfur cluster biosynthetic enzyme
LM596_RS12365	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
LM596_RS12375	COG1917	Cupin 2, conserved barrel domain protein
LM596_RS12375	COG4977	sequence-specific DNA binding
LM596_RS12465	COG2814	Major facilitator Superfamily
LM596_RS12480	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LM596_RS12490	COG1174	glycine betaine transport
LM596_RS12500	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LM596_RS12515	COG2217	Heavy metal translocating P-type atpase
LM596_RS12555	COG2801	Transposase and inactivated derivatives
LM596_RS12565	COG0435	Glutathione S-transferase
LM596_RS12585	COG0534	Mate efflux family protein
LM596_RS12610	COG4876	unkown
LM596_RS12630	COG1192	Involved in chromosome partitioning
LM596_RS12685	COG1192	Involved in chromosome partitioning
LM596_RS12695	COG3409	Peptidoglycan-binding domain 1 protein
LM596_RS12750	COG3189	MarR family transcriptional regulator
LM596_RS12895	COG0626	cystathionine gamma-synthase activity