locus-tag	class	description
EMK97_RS00010	COG3293	Transposase
EMK97_RS00015	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EMK97_RS00035	COG0515	serine threonine protein kinase
EMK97_RS00040	COG2203	Gaf domain
EMK97_RS00040	COG3706	GGDEF domain
EMK97_RS00040	COG4251	negative regulation of phosphorylation
EMK97_RS00040	COG5001	Diguanylate cyclase
EMK97_RS00045	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EMK97_RS00050	COG0321	lipoyl(octanoyl) transferase activity
EMK97_RS00055	COG2921	Belongs to the UPF0250 family
EMK97_RS00065	COG1309	transcriptional regulator
EMK97_RS00080	COG2186	Transcriptional regulator
EMK97_RS00085	COG2719	SpoVR family
EMK97_RS00090	COG2718	Belongs to the UPF0229 family
EMK97_RS00095	COG2766	serine protein kinase
EMK97_RS00105	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EMK97_RS00110	COG0450	alkyl hydroperoxide reductase
EMK97_RS00115	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EMK97_RS00130	COG3706	GGDEF domain
EMK97_RS00160	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EMK97_RS00175	COG0545	Peptidyl-prolyl cis-trans isomerase
EMK97_RS00185	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EMK97_RS00190	COG0505	Belongs to the CarA family
EMK97_RS00195	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EMK97_RS00200	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EMK97_RS00205	COG5001	Diguanylate cyclase
EMK97_RS00205	COG4251	negative regulation of phosphorylation
EMK97_RS00205	COG3706	GGDEF domain
EMK97_RS00205	COG2203	Gaf domain
EMK97_RS00230	COG1404	Belongs to the peptidase S8 family
EMK97_RS00235	COG1534	Rna-binding protein
EMK97_RS00240	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
EMK97_RS00250	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EMK97_RS00255	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EMK97_RS00260	COG0149	triose-phosphate isomerase activity
EMK97_RS00265	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EMK97_RS00275	COG5001	Diguanylate cyclase
EMK97_RS00275	COG3447	MASE1 domain protein
EMK97_RS00275	COG5002	protein histidine kinase activity
EMK97_RS00290	COG0189	ligase activity
EMK97_RS00300	COG4067	protein conserved in archaea
EMK97_RS00300	COG0189	ligase activity
EMK97_RS00305	COG3264	Mechanosensitive ion channel
EMK97_RS00305	COG1196	nuclear chromosome segregation
EMK97_RS00320	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EMK97_RS00325	COG4948	Mandelate Racemase Muconate Lactonizing
EMK97_RS00345	COG0840	transmembrane signaling receptor activity
EMK97_RS00355	COG0232	Belongs to the dGTPase family. Type 2 subfamily
EMK97_RS00360	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EMK97_RS00365	COG2226	methyltransferase
EMK97_RS00375	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EMK97_RS00380	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EMK97_RS00385	COG0632	four-way junction helicase activity
EMK97_RS00390	COG2255	four-way junction helicase activity
EMK97_RS00400	COG0658	competence protein
EMK97_RS00400	COG2333	competence protein COMEC
EMK97_RS00405	COG1132	(ABC) transporter
EMK97_RS00415	COG2835	tetraacyldisaccharide 4'-kinase activity
EMK97_RS00420	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
EMK97_RS00425	COG3154	lipid carrier protein
EMK97_RS00430	COG0826	peptidase U32
EMK97_RS00435	COG0826	peptidase U32
EMK97_RS00440	COG2850	peptidyl-arginine hydroxylation
EMK97_RS00450	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
EMK97_RS00455	COG1187	pseudouridine synthase activity
EMK97_RS00470	COG3293	Transposase
EMK97_RS00475	COG2423	ornithine cyclodeaminase activity
EMK97_RS00480	COG0006	proline dipeptidase activity
EMK97_RS00490	COG3104	oligopeptide transport
EMK97_RS00500	COG4191	Histidine kinase
EMK97_RS00500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EMK97_RS00515	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EMK97_RS00520	COG1555	photosystem II stabilization
EMK97_RS00530	COG0175	sulfate reduction
EMK97_RS00535	COG2895	sulfate adenylyltransferase (ATP) activity
EMK97_RS00540	COG0471	metal ion transport
EMK97_RS00540	COG3273	potassium ion transport
EMK97_RS00545	COG0529	Catalyzes the synthesis of activated sulfate
EMK97_RS00555	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EMK97_RS00565	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
EMK97_RS00570	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EMK97_RS00580	COG0784	Response regulator, receiver
EMK97_RS00580	COG3437	response regulator, receiver
EMK97_RS00600	COG0730	response to heat
EMK97_RS00625	COG0741	lytic transglycosylase activity
EMK97_RS00635	COG1573	uracil-dna glycosylase
EMK97_RS00645	COG0517	IMP dehydrogenase activity
EMK97_RS00645	COG0516	GMP reductase activity
EMK97_RS00650	COG1643	Atp-dependent helicase
EMK97_RS00660	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EMK97_RS00665	COG1254	Belongs to the acylphosphatase family
EMK97_RS00680	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EMK97_RS00740	COG1960	acyl-CoA dehydrogenase activity
EMK97_RS00750	COG1960	acyl-CoA dehydrogenase activity
EMK97_RS00755	COG0121	glutamine amidotransferase
EMK97_RS00840	COG0534	Mate efflux family protein
EMK97_RS00860	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
EMK97_RS00875	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EMK97_RS00880	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EMK97_RS00885	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EMK97_RS00890	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EMK97_RS00895	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EMK97_RS00930	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EMK97_RS00935	COG2915	High frequency lysogenization protein hflD homolog
EMK97_RS00940	COG0482	sulfurtransferase activity
EMK97_RS00945	COG1187	pseudouridine synthase activity
EMK97_RS00960	COG1278	Cold shock
EMK97_RS00965	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EMK97_RS00970	COG0542	response to heat
EMK97_RS01005	COG4948	Mandelate Racemase Muconate Lactonizing
EMK97_RS01010	COG0626	cystathionine gamma-synthase activity
EMK97_RS01015	COG0534	Mate efflux family protein
EMK97_RS01020	COG0556	nucleotide-excision repair
EMK97_RS01030	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EMK97_RS01035	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EMK97_RS01040	COG0602	queuosine metabolic process
EMK97_RS01060	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EMK97_RS01080	COG0545	Peptidyl-prolyl cis-trans isomerase
EMK97_RS01105	COG0739	heme binding
EMK97_RS01110	COG2759	Belongs to the formate--tetrahydrofolate ligase family
EMK97_RS01120	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EMK97_RS01130	COG3383	formate dehydrogenase (NAD+) activity
EMK97_RS01265	COG5265	(ABC) transporter
EMK97_RS01285	COG2992	FlgJ-related protein
EMK97_RS01290	COG0037	tRNA processing
EMK97_RS01295	COG0589	response to stress
EMK97_RS01300	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EMK97_RS01325	COG2010	Cytochrome c
EMK97_RS01340	COG3278	Belongs to the heme-copper respiratory oxidase family
EMK97_RS01345	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EMK97_RS01355	COG1388	LysM domain
EMK97_RS01355	COG0741	lytic transglycosylase activity
EMK97_RS01365	COG2226	methyltransferase
EMK97_RS01370	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EMK97_RS01375	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EMK97_RS01390	COG0527	aspartate kinase activity
EMK97_RS01395	COG0386	Belongs to the glutathione peroxidase family
EMK97_RS01400	COG2084	Dehydrogenase
EMK97_RS01410	COG0471	metal ion transport
EMK97_RS01425	COG2204	response regulator
EMK97_RS01430	COG2925	Exonuclease
EMK97_RS01435	COG1253	flavin adenine dinucleotide binding
EMK97_RS01450	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EMK97_RS01475	COG2205	protein histidine kinase activity
EMK97_RS01480	COG3064	Membrane
EMK97_RS01505	COG0642	Histidine kinase
EMK97_RS01510	COG0745	RESPONSE REGULATOR receiver
EMK97_RS01540	COG1199	ATP-dependent helicase activity
EMK97_RS01545	COG0417	DNA replication proofreading
EMK97_RS01560	COG0537	adenosine 5'-monophosphoramidase activity
EMK97_RS01565	COG3275	phosphorelay sensor kinase activity
EMK97_RS01570	COG3279	Response regulator of the LytR AlgR family
EMK97_RS01575	COG0469	pyruvate kinase activity
EMK97_RS01580	COG1737	Transcriptional regulator
EMK97_RS01585	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EMK97_RS01590	COG0363	glucosamine-6-phosphate deaminase activity
EMK97_RS01595	COG0129	dihydroxy-acid dehydratase activity
EMK97_RS01600	COG0800	Aldolase
EMK97_RS01615	COG1530	ribonuclease E activity
EMK97_RS01630	COG1399	metal-binding, possibly nucleic acid-binding protein
EMK97_RS01635	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EMK97_RS01640	COG0416	fatty acid biosynthetic process
EMK97_RS01645	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EMK97_RS01655	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EMK97_RS01660	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EMK97_RS01665	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EMK97_RS01670	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EMK97_RS01675	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EMK97_RS01690	COG0084	hydrolase, TatD family'
EMK97_RS01695	COG0475	glutathione-regulated potassium exporter activity
EMK97_RS01705	COG4181	ATPase activity
EMK97_RS01725	COG0628	permease
EMK97_RS01735	COG2350	Protein conserved in bacteria
EMK97_RS01745	COG0006	proline dipeptidase activity
EMK97_RS01750	COG0714	Associated with various cellular activities
EMK97_RS01755	COG1845	cytochrome c oxidase, subunit III
EMK97_RS01785	COG0745	RESPONSE REGULATOR receiver
EMK97_RS01790	COG0643	Histidine kinase
EMK97_RS01790	COG2198	Histidine kinase
EMK97_RS01795	COG0835	chemotaxis
EMK97_RS01800	COG0835	chemotaxis
EMK97_RS01805	COG0840	transmembrane signaling receptor activity
EMK97_RS01810	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EMK97_RS01815	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
EMK97_RS01820	COG2201	protein-glutamate methylesterase activity
EMK97_RS01825	COG0840	transmembrane signaling receptor activity
EMK97_RS01850	COG3706	GGDEF domain
EMK97_RS01860	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EMK97_RS01865	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EMK97_RS01870	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EMK97_RS01885	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EMK97_RS01890	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EMK97_RS01895	COG0539	negative regulation of cytoplasmic translation
EMK97_RS01900	COG0776	regulation of translation
EMK97_RS01910	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
EMK97_RS01915	COG0284	orotidine-5'-phosphate decarboxylase activity
EMK97_RS01925	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EMK97_RS01930	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EMK97_RS01950	COG2920	part of a sulfur-relay system
EMK97_RS01960	COG2923	Belongs to the DsrF TusC family
EMK97_RS01970	COG0670	Belongs to the BI1 family
EMK97_RS01975	COG0519	Catalyzes the synthesis of GMP from XMP
EMK97_RS01985	COG3293	Transposase
EMK97_RS02020	COG5507	3-demethylubiquinone-9 3-methyltransferase
EMK97_RS02080	COG0418	dihydroorotase activity
EMK97_RS02085	COG3081	Nucleoid-associated protein
EMK97_RS02090	COG3082	Protein of unknown function (DUF1414)
EMK97_RS02225	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EMK97_RS02240	COG2226	methyltransferase
EMK97_RS02240	COG1073	alpha beta
EMK97_RS02250	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EMK97_RS02265	COG0017	Asparaginyl-tRNA synthetase
EMK97_RS02270	COG0778	Nitroreductase
EMK97_RS02275	COG0697	spore germination
EMK97_RS02285	COG0616	signal peptide processing
EMK97_RS02290	COG0252	asparaginase activity
EMK97_RS02325	COG1115	amino acid carrier protein
EMK97_RS02330	COG2866	Carboxypeptidase
EMK97_RS02340	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EMK97_RS02345	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EMK97_RS02350	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EMK97_RS02355	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EMK97_RS02360	COG1674	ftsk spoiiie
EMK97_RS02360	COG0531	amino acid
EMK97_RS02375	COG0686	Belongs to the AlaDH PNT family
EMK97_RS02380	COG0492	ferredoxin-NADP+ reductase activity
EMK97_RS02390	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
EMK97_RS02395	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EMK97_RS02425	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EMK97_RS02430	COG1074	ATP-dependent DNA helicase activity
EMK97_RS02435	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
EMK97_RS02455	COG0714	Associated with various cellular activities
EMK97_RS02460	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EMK97_RS02490	COG0367	asparagine synthase
EMK97_RS02505	COG0167	dihydroorotate dehydrogenase activity
EMK97_RS02510	COG2902	Dehydrogenase
EMK97_RS02540	COG0308	aminopeptidase N
EMK97_RS02545	COG1757	Na H antiporter
EMK97_RS02555	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
EMK97_RS02565	COG1956	GAF domain-containing protein
EMK97_RS02580	COG2828	Protein conserved in bacteria
EMK97_RS02590	COG0372	Belongs to the citrate synthase family
EMK97_RS02595	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EMK97_RS02640	COG0717	Belongs to the dCTP deaminase family
EMK97_RS02645	COG0489	protein tyrosine kinase activity
EMK97_RS02650	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EMK97_RS02650	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EMK97_RS02655	COG1301	dicarboxylic acid transport
EMK97_RS02665	COG1720	tRNA m6t6A37 methyltransferase activity
EMK97_RS02675	COG1047	Peptidyl-prolyl cis-trans
EMK97_RS02685	COG0419	ATPase involved in DNA repair
EMK97_RS02690	COG0420	3'-5' exonuclease activity
EMK97_RS02700	COG0583	DNA-binding transcription factor activity
EMK97_RS02725	COG1629	transport
EMK97_RS02725	COG4774	siderophore transport
EMK97_RS02740	COG2329	Antibiotic biosynthesis monooxygenase
EMK97_RS02750	COG0625	glutathione transferase activity
EMK97_RS02805	COG1566	PFAM secretion protein HlyD family protein
EMK97_RS02810	COG0776	regulation of translation
EMK97_RS02815	COG0072	phenylalanine-tRNA ligase activity
EMK97_RS02815	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EMK97_RS02820	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EMK97_RS02840	COG0277	FAD linked oxidase domain protein
EMK97_RS02845	COG0574	Belongs to the PEP-utilizing enzyme family
EMK97_RS02845	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EMK97_RS02850	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EMK97_RS02855	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EMK97_RS02860	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EMK97_RS02880	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
EMK97_RS02905	COG0405	Gamma-glutamyltransferase
EMK97_RS02915	COG0705	Rhomboid family
EMK97_RS02925	COG3012	SEC-C Motif Domain Protein
EMK97_RS02935	COG2205	protein histidine kinase activity
EMK97_RS02940	COG0745	RESPONSE REGULATOR receiver
EMK97_RS02945	COG0708	Exodeoxyribonuclease III
EMK97_RS02950	COG2226	methyltransferase
EMK97_RS02965	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EMK97_RS02975	COG0280	phosphate acetyltransferase
EMK97_RS02975	COG0857	belongs to the CobB CobQ family
EMK97_RS02985	COG1393	Belongs to the ArsC family
EMK97_RS02990	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EMK97_RS03015	COG2716	regulation of RNA biosynthetic process
EMK97_RS03040	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EMK97_RS03070	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EMK97_RS03080	COG0515	serine threonine protein kinase
EMK97_RS03080	COG0457	Tetratricopeptide repeat
EMK97_RS03090	COG0732	type I restriction modification DNA specificity domain
EMK97_RS03095	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
EMK97_RS03125	COG1803	Methylglyoxal synthase
EMK97_RS03135	COG1858	cytochrome C peroxidase
EMK97_RS03155	COG4783	chaperone-mediated protein folding
EMK97_RS03160	COG1393	Belongs to the ArsC family
EMK97_RS03185	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EMK97_RS03190	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EMK97_RS03280	COG0631	protein serine/threonine phosphatase activity
EMK97_RS03285	COG0515	serine threonine protein kinase
EMK97_RS03285	COG2815	serine threonine protein kinase
EMK97_RS03315	COG1032	radical SAM domain protein
EMK97_RS03320	COG0488	(ABC) transporter
EMK97_RS03335	COG5002	protein histidine kinase activity
EMK97_RS03380	COG3385	transposase activity
EMK97_RS03450	COG3034	peptidoglycan biosynthetic process
EMK97_RS03500	COG1881	PFAM PEBP family protein
EMK97_RS03505	COG0513	Belongs to the DEAD box helicase family
EMK97_RS03515	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EMK97_RS03545	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EMK97_RS03570	COG0442	prolyl-tRNA aminoacylation
EMK97_RS03575	COG0436	Aminotransferase
EMK97_RS03580	COG0427	acetyl-CoA hydrolase
EMK97_RS03585	COG3005	denitrification pathway
EMK97_RS03595	COG0348	domain, Protein
EMK97_RS03600	COG0437	4 iron, 4 sulfur cluster binding
EMK97_RS03605	COG0243	molybdopterin cofactor binding
EMK97_RS03620	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
EMK97_RS03620	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EMK97_RS03630	COG3291	Pkd domain containing protein
EMK97_RS03890	COG0443	Heat shock 70 kDa protein
EMK97_RS03910	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EMK97_RS03915	COG0045	succinate-CoA ligase (ADP-forming) activity
EMK97_RS03920	COG0508	dehydrogenase complex catalyzes the overall conversion of
EMK97_RS03925	COG0567	Dehydrogenase, E1 component
EMK97_RS03930	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EMK97_RS03935	COG1053	succinate dehydrogenase
EMK97_RS03940	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
EMK97_RS03945	COG2009	succinate dehydrogenase
EMK97_RS03955	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EMK97_RS03960	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EMK97_RS03980	COG1185	polyribonucleotide nucleotidyltransferase activity
EMK97_RS03985	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EMK97_RS03990	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EMK97_RS03995	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EMK97_RS04000	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EMK97_RS04005	COG0195	Participates in both transcription termination and antitermination
EMK97_RS04010	COG0779	Required for maturation of 30S ribosomal subunits
EMK97_RS04015	COG2199	diguanylate cyclase activity
EMK97_RS04015	COG2203	Gaf domain
EMK97_RS04015	COG2200	EAL domain
EMK97_RS04020	COG4657	Part of a membrane complex involved in electron transport
EMK97_RS04025	COG2878	Part of a membrane complex involved in electron transport
EMK97_RS04030	COG4656	Part of a membrane complex involved in electron transport
EMK97_RS04035	COG4658	electron transport chain
EMK97_RS04040	COG4659	FMN binding
EMK97_RS04045	COG4660	Part of a membrane complex involved in electron transport
EMK97_RS04050	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EMK97_RS04060	COG1278	Cold shock
EMK97_RS04065	COG0114	fumarate hydratase activity
EMK97_RS04070	COG2203	Gaf domain
EMK97_RS04070	COG2199	diguanylate cyclase activity
EMK97_RS04080	COG0346	lactoylglutathione lyase activity
EMK97_RS04085	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EMK97_RS04090	COG4681	YaeQ
EMK97_RS04110	COG3291	Pkd domain containing protein
EMK97_RS04120	COG1984	allophanate hydrolase subunit 2
EMK97_RS04125	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EMK97_RS04130	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EMK97_RS04145	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
EMK97_RS04165	COG3437	response regulator, receiver
EMK97_RS04170	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EMK97_RS04180	COG0840	transmembrane signaling receptor activity
EMK97_RS04210	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
EMK97_RS04230	COG1028	Short-chain dehydrogenase reductase Sdr
EMK97_RS04240	COG3706	GGDEF domain
EMK97_RS04255	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EMK97_RS04265	COG0813	purine-nucleoside phosphorylase activity
EMK97_RS04270	COG4771	TonB-dependent receptor
EMK97_RS04280	COG0572	uridine kinase
EMK97_RS04285	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EMK97_RS04295	COG1435	thymidine kinase activity
EMK97_RS04300	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EMK97_RS04325	COG1309	transcriptional regulator
EMK97_RS04335	COG1785	Belongs to the alkaline phosphatase family
EMK97_RS04340	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EMK97_RS04345	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EMK97_RS04360	COG2814	Major facilitator Superfamily
EMK97_RS04365	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EMK97_RS04375	COG2840	Smr protein MutS2
EMK97_RS04380	COG2062	phosphohistidine phosphatase, SixA
EMK97_RS04405	COG1250	3-hydroxyacyl-CoA dehydrogenase
EMK97_RS04405	COG1024	Enoyl-CoA hydratase
EMK97_RS04410	COG0183	Belongs to the thiolase family
EMK97_RS04415	COG0714	Associated with various cellular activities
EMK97_RS04435	COG2304	oxidoreductase activity
EMK97_RS04445	COG1595	DNA-templated transcription, initiation
EMK97_RS04455	COG0028	Belongs to the TPP enzyme family
EMK97_RS04470	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EMK97_RS04485	COG0583	DNA-binding transcription factor activity
EMK97_RS04490	COG2204	response regulator
EMK97_RS04495	COG2204	response regulator
EMK97_RS04505	COG1863	multisubunit Na H antiporter MnhE subunit
EMK97_RS04515	COG1320	monovalent cation:proton antiporter activity
EMK97_RS04525	COG1006	Multisubunit Na H antiporter MnhC subunit
EMK97_RS04530	COG0651	ATP synthesis coupled electron transport
EMK97_RS04535	COG0651	ATP synthesis coupled electron transport
EMK97_RS04545	COG0651	ATP synthesis coupled electron transport
EMK97_RS04550	COG1162	GTPase activity
EMK97_RS04600	COG0322	excinuclease ABC activity
EMK97_RS04605	COG2197	response regulator
EMK97_RS04615	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EMK97_RS04620	COG3130	regulation of translation
EMK97_RS04635	COG0488	(ABC) transporter
EMK97_RS04645	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EMK97_RS04645	COG0116	Belongs to the methyltransferase superfamily
EMK97_RS04665	COG2017	converts alpha-aldose to the beta-anomer
EMK97_RS04675	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EMK97_RS04680	COG1085	galactose-1-phosphate uridylyltransferase
EMK97_RS04685	COG2169	Transcriptional regulator
EMK97_RS04690	COG4591	ABC-type transport system involved in lipoprotein release permease component
EMK97_RS04700	COG4591	ABC-type transport system involved in lipoprotein release permease component
EMK97_RS04710	COG0840	transmembrane signaling receptor activity
EMK97_RS04715	COG0840	transmembrane signaling receptor activity
EMK97_RS04725	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EMK97_RS04730	COG0288	reversible hydration of carbon dioxide
EMK97_RS04750	COG0456	acetyltransferase
EMK97_RS04750	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EMK97_RS04795	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EMK97_RS04825	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EMK97_RS04850	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
EMK97_RS04855	COG2885	chlorophyll binding
EMK97_RS04860	COG0823	Involved in the tonB-independent uptake of proteins
EMK97_RS04875	COG0811	peptide transport
EMK97_RS04880	COG0824	Thioesterase
EMK97_RS04885	COG0513	Belongs to the DEAD box helicase family
EMK97_RS04895	COG0823	Involved in the tonB-independent uptake of proteins
EMK97_RS04895	COG4946	Tricorn protease homolog
EMK97_RS04895	COG1506	peptidase
EMK97_RS04910	COG1067	ATP-dependent peptidase activity
EMK97_RS04915	COG2888	peptidyl-tyrosine sulfation
EMK97_RS04920	COG0495	leucyl-tRNA aminoacylation
EMK97_RS04925	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
EMK97_RS04930	COG1466	dna polymerase III delta subunit
EMK97_RS04935	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EMK97_RS04940	COG0799	negative regulation of ribosome biogenesis
EMK97_RS04945	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EMK97_RS04950	COG0768	penicillin binding
EMK97_RS04955	COG0772	Belongs to the SEDS family
EMK97_RS04960	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EMK97_RS04965	COG1686	Belongs to the peptidase S11 family
EMK97_RS04980	COG0022	dehydrogenase e1 component
EMK97_RS04985	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EMK97_RS04990	COG0840	transmembrane signaling receptor activity
EMK97_RS04995	COG0033	Phosphoglucomutase
EMK97_RS05005	COG0596	Alpha beta hydrolase
EMK97_RS05020	COG0716	FMN binding
EMK97_RS05025	COG0735	belongs to the Fur family
EMK97_RS05030	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
EMK97_RS05035	COG0037	tRNA processing
EMK97_RS05040	COG0825	malonyl-CoA metabolic process
EMK97_RS05045	COG0587	DNA-directed DNA polymerase activity
EMK97_RS05050	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EMK97_RS05055	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EMK97_RS05060	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EMK97_RS05065	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EMK97_RS05075	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
EMK97_RS05085	COG0750	zinc metalloprotease
EMK97_RS05090	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EMK97_RS05095	COG0575	Belongs to the CDS family
EMK97_RS05100	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EMK97_RS05105	COG0233	cytoplasmic translational termination
EMK97_RS05110	COG0528	UMP kinase activity
EMK97_RS05120	COG0052	Belongs to the universal ribosomal protein uS2 family
EMK97_RS05130	COG0024	Methionine aminopeptidase
EMK97_RS05135	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
EMK97_RS05140	COG2171	N-acyltransferase activity
EMK97_RS05150	COG0564	pseudouridine synthase activity
EMK97_RS05155	COG3098	single-species biofilm formation
EMK97_RS05180	COG1492	cobalamin metabolic process
EMK97_RS05195	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
EMK97_RS05200	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
EMK97_RS05205	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EMK97_RS05215	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EMK97_RS05225	COG3104	oligopeptide transport
EMK97_RS05230	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EMK97_RS05235	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EMK97_RS05240	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EMK97_RS05255	COG0583	DNA-binding transcription factor activity
EMK97_RS05260	COG3547	Transposase (IS116 IS110 IS902 family)
EMK97_RS05265	COG3148	PFAM DTW domain containing protein
EMK97_RS05275	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EMK97_RS05280	COG0513	Belongs to the DEAD box helicase family
EMK97_RS05300	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EMK97_RS05310	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EMK97_RS05315	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EMK97_RS05320	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EMK97_RS05325	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EMK97_RS05330	COG2853	Lipoprotein
EMK97_RS05340	COG0835	chemotaxis
EMK97_RS05350	COG1192	Involved in chromosome partitioning
EMK97_RS05355	COG1360	Flagellar Motor Protein
EMK97_RS05360	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EMK97_RS05370	COG2198	Histidine kinase
EMK97_RS05370	COG0784	Response regulator, receiver
EMK97_RS05370	COG0643	Histidine kinase
EMK97_RS05375	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
EMK97_RS05410	COG1684	flagellar biosynthetic protein fliR
EMK97_RS05465	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EMK97_RS05470	COG1766	The M ring may be actively involved in energy transduction
EMK97_RS05475	COG1677	Flagellar hook-basal body complex protein FliE
EMK97_RS05500	COG1086	Polysaccharide biosynthesis protein
EMK97_RS05505	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EMK97_RS05515	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
EMK97_RS05540	COG2089	acid synthase
EMK97_RS05555	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EMK97_RS05575	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EMK97_RS05605	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EMK97_RS05615	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EMK97_RS05620	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EMK97_RS05625	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EMK97_RS05635	COG1256	bacterial-type flagellum assembly
EMK97_RS05640	COG3951	Flagellar rod assembly protein muramidase FlgJ
EMK97_RS05640	COG1705	Flagellar rod assembly protein muramidase FlgJ
EMK97_RS05645	COG1706	bacterial-type flagellum-dependent cell motility
EMK97_RS05650	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
EMK97_RS05655	COG4786	Flagellar basal body rod
EMK97_RS05660	COG4786	Flagellar basal body rod
EMK97_RS05665	COG1749	Flagellar hook protein flgE
EMK97_RS05670	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EMK97_RS05680	COG1815	bacterial-type flagellum-dependent cell motility
EMK97_RS05685	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EMK97_RS05690	COG0835	chemotaxis
EMK97_RS05690	COG0784	Response regulator, receiver
EMK97_RS05735	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EMK97_RS05740	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EMK97_RS05745	COG0126	phosphoglycerate kinase activity
EMK97_RS05760	COG0488	(ABC) transporter
EMK97_RS05780	COG5002	protein histidine kinase activity
EMK97_RS05785	COG0745	RESPONSE REGULATOR receiver
EMK97_RS05800	COG4191	Histidine kinase
EMK97_RS05805	COG2974	May be involved in recombination
EMK97_RS05815	COG0826	peptidase U32
EMK97_RS05820	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EMK97_RS05825	COG0583	DNA-binding transcription factor activity
EMK97_RS05835	COG3385	transposase activity
EMK97_RS05845	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EMK97_RS05860	COG1301	dicarboxylic acid transport
EMK97_RS05865	COG0616	signal peptide processing
EMK97_RS05870	COG2267	carboxylic ester hydrolase activity
EMK97_RS05875	COG1028	Short-chain dehydrogenase reductase Sdr
EMK97_RS05895	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EMK97_RS05940	COG1088	dTDP-glucose 4,6-dehydratase activity
EMK97_RS05945	COG1091	dTDP-4-dehydrorhamnose reductase activity
EMK97_RS05970	COG1450	Type ii and iii secretion system protein
EMK97_RS06010	COG1459	type II secretion system
EMK97_RS06015	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EMK97_RS06035	COG0318	PFAM AMP-dependent synthetase and ligase
EMK97_RS06055	COG1214	PFAM Peptidase M22, glycoprotease
EMK97_RS06060	COG1199	ATP-dependent helicase activity
EMK97_RS06075	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EMK97_RS06080	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EMK97_RS06090	COG0131	Imidazoleglycerol-phosphate dehydratase
EMK97_RS06090	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EMK97_RS06095	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EMK97_RS06100	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EMK97_RS06105	COG0107	imidazoleglycerol-phosphate synthase activity
EMK97_RS06110	COG0140	phosphoribosyl-ATP diphosphatase activity
EMK97_RS06110	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EMK97_RS06125	COG2153	protein acetylation
EMK97_RS06135	COG0563	adenylate kinase activity
EMK97_RS06140	COG0326	Molecular chaperone. Has ATPase activity
EMK97_RS06170	COG0542	response to heat
EMK97_RS06180	COG0564	pseudouridine synthase activity
EMK97_RS06185	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EMK97_RS06195	COG0347	Belongs to the P(II) protein family
EMK97_RS06200	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EMK97_RS06210	COG4969	Belongs to the N-Me-Phe pilin family
EMK97_RS06245	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EMK97_RS06250	COG1047	Peptidyl-prolyl cis-trans
EMK97_RS06255	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EMK97_RS06260	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EMK97_RS06265	COG0196	riboflavin kinase activity
EMK97_RS06270	COG0728	peptidoglycan biosynthetic process
EMK97_RS06275	COG0268	Binds directly to 16S ribosomal RNA
EMK97_RS06285	COG0840	transmembrane signaling receptor activity
EMK97_RS06295	COG1960	acyl-CoA dehydrogenase activity
EMK97_RS06305	COG1404	Belongs to the peptidase S8 family
EMK97_RS06325	COG4948	Mandelate Racemase Muconate Lactonizing
EMK97_RS06355	COG2193	ferroxidase activity
EMK97_RS06365	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EMK97_RS06380	COG4206	TonB-dependent receptor
EMK97_RS06385	COG0840	transmembrane signaling receptor activity
EMK97_RS06400	COG0643	Histidine kinase
EMK97_RS06400	COG2198	Histidine kinase
EMK97_RS06405	COG0835	chemotaxis
EMK97_RS06410	COG0840	transmembrane signaling receptor activity
EMK97_RS06420	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
EMK97_RS06425	COG2201	protein-glutamate methylesterase activity
EMK97_RS06435	COG0745	RESPONSE REGULATOR receiver
EMK97_RS06445	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
EMK97_RS06450	COG0583	DNA-binding transcription factor activity
EMK97_RS06465	COG0494	nUDIX hydrolase
EMK97_RS06470	COG0840	transmembrane signaling receptor activity
EMK97_RS06495	COG0189	ligase activity
EMK97_RS06510	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EMK97_RS06515	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EMK97_RS06525	COG2207	Transcriptional regulator
EMK97_RS06550	COG2205	protein histidine kinase activity
EMK97_RS06550	COG2770	Histidine kinase
EMK97_RS06555	COG0745	RESPONSE REGULATOR receiver
EMK97_RS06570	COG1136	(ABC) transporter
EMK97_RS06590	COG1335	isochorismatase
EMK97_RS06600	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EMK97_RS06615	COG1166	arginine decarboxylase activity
EMK97_RS06640	COG0189	ligase activity
EMK97_RS06650	COG0583	DNA-binding transcription factor activity
EMK97_RS06670	COG0443	Heat shock 70 kDa protein
EMK97_RS06685	COG0822	iron-sulfur transferase activity
EMK97_RS06690	COG1104	cysteine desulfurase activity
EMK97_RS06700	COG1045	serine acetyltransferase
EMK97_RS06705	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
EMK97_RS06710	COG0483	inositol monophosphate 1-phosphatase activity
EMK97_RS06715	COG1648	precorrin-2 dehydrogenase activity
EMK97_RS06715	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EMK97_RS06720	COG0513	Belongs to the DEAD box helicase family
EMK97_RS06725	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EMK97_RS06730	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EMK97_RS06735	COG1862	Preprotein translocase
EMK97_RS06740	COG0343	queuine tRNA-ribosyltransferase activity
EMK97_RS06745	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EMK97_RS06765	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
EMK97_RS06790	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EMK97_RS06795	COG0018	arginyl-trna synthetase
EMK97_RS06800	COG0084	hydrolase, TatD family'
EMK97_RS06810	COG0560	Phosphoserine phosphatase
EMK97_RS06820	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EMK97_RS06845	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EMK97_RS06860	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EMK97_RS06870	COG1410	methionine synthase
EMK97_RS06870	COG0646	methionine synthase
EMK97_RS06875	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EMK97_RS06880	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EMK97_RS06885	COG5002	protein histidine kinase activity
EMK97_RS06885	COG5001	Diguanylate cyclase
EMK97_RS06890	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EMK97_RS06900	COG4942	peptidase
EMK97_RS06900	COG1388	LysM domain
EMK97_RS06905	COG1238	metal cluster binding
EMK97_RS06910	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EMK97_RS06915	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
EMK97_RS06925	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EMK97_RS06935	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
EMK97_RS06955	COG1131	(ABC) transporter
EMK97_RS06965	COG1444	tRNA N-acetyltransferase activity
EMK97_RS06975	COG0259	pyridoxamine-phosphate oxidase activity
EMK97_RS06980	COG0501	Belongs to the peptidase M48B family
EMK97_RS06985	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
EMK97_RS07015	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
EMK97_RS07020	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EMK97_RS07025	COG2137	regulation of response to DNA damage stimulus
EMK97_RS07030	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EMK97_RS07060	COG2239	Acts as a magnesium transporter
EMK97_RS07065	COG0583	DNA-binding transcription factor activity
EMK97_RS07070	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EMK97_RS07075	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EMK97_RS07095	COG1138	Cytochrome C-type biogenesis protein
EMK97_RS07105	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EMK97_RS07110	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EMK97_RS07115	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EMK97_RS07120	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
EMK97_RS07135	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EMK97_RS07140	COG2971	BadF BadG BcrA BcrD
EMK97_RS07170	COG0166	Belongs to the GPI family
EMK97_RS07175	COG1609	Transcriptional regulator
EMK97_RS07180	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
EMK97_RS07185	COG0204	Acyl-transferase
EMK97_RS07200	COG0625	glutathione transferase activity
EMK97_RS07205	COG3842	ATPase activity
EMK97_RS07215	COG1840	ABC-type Fe3 transport system, periplasmic component
EMK97_RS07235	COG0363	glucosamine-6-phosphate deaminase activity
EMK97_RS07240	COG1090	epimerase
EMK97_RS07260	COG3291	Pkd domain containing protein
EMK97_RS07270	COG0390	transport system, permease component
EMK97_RS07275	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
EMK97_RS07290	COG0697	spore germination
EMK97_RS07305	COG1028	Short-chain dehydrogenase reductase Sdr
EMK97_RS07315	COG2252	PERMEase
EMK97_RS07330	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EMK97_RS07345	COG2184	nucleotidyltransferase activity
EMK97_RS07355	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EMK97_RS07380	COG1131	(ABC) transporter
EMK97_RS07385	COG0071	Belongs to the small heat shock protein (HSP20) family
EMK97_RS07405	COG1309	transcriptional regulator
EMK97_RS07440	COG0795	lipopolysaccharide-transporting ATPase activity
EMK97_RS07445	COG0795	lipopolysaccharide-transporting ATPase activity
EMK97_RS07450	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EMK97_RS07455	COG2927	DNA polymerase III (CHI subunit)
EMK97_RS07460	COG0525	valine-tRNA ligase activity
EMK97_RS07465	COG1278	Cold shock
EMK97_RS07490	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EMK97_RS07490	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EMK97_RS07495	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EMK97_RS07505	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EMK97_RS07515	COG1595	DNA-templated transcription, initiation
EMK97_RS07525	COG4555	ABC transporter
EMK97_RS07540	COG1272	protein, Hemolysin III
EMK97_RS07565	COG3313	Fe-S protein
EMK97_RS07570	COG0659	secondary active sulfate transmembrane transporter activity
EMK97_RS07585	COG3938	Belongs to the proline racemase family
EMK97_RS07595	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EMK97_RS07595	COG4191	Histidine kinase
EMK97_RS07600	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EMK97_RS07610	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EMK97_RS07615	COG3171	Protein conserved in bacteria
EMK97_RS07620	COG1194	a g-specific adenine glycosylase
EMK97_RS07625	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
EMK97_RS07655	COG4206	TonB-dependent receptor
EMK97_RS07660	COG1288	antiporter activity
EMK97_RS07665	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EMK97_RS07675	COG0583	DNA-binding transcription factor activity
EMK97_RS07695	COG4774	siderophore transport
EMK97_RS07730	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EMK97_RS07745	COG3706	GGDEF domain
EMK97_RS07755	COG0405	Gamma-glutamyltransferase
EMK97_RS07770	COG0628	permease
EMK97_RS07790	COG0217	transcriptional regulatory protein
EMK97_RS07800	COG4771	TonB-dependent receptor
EMK97_RS07810	COG3293	Transposase
EMK97_RS07830	COG3385	transposase activity
EMK97_RS07840	COG3706	GGDEF domain
EMK97_RS07845	COG3706	GGDEF domain
EMK97_RS07850	COG0187	DNA topoisomerase II activity
EMK97_RS07855	COG3150	esterase
EMK97_RS07865	COG3151	Protein conserved in bacteria
EMK97_RS07870	COG0494	nUDIX hydrolase
EMK97_RS07875	COG1538	Outer membrane efflux protein
EMK97_RS07880	COG0438	transferase activity, transferring glycosyl groups
EMK97_RS07885	COG1560	Kdo2-lipid A biosynthetic process
EMK97_RS07895	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
EMK97_RS07910	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EMK97_RS07940	COG1388	LysM domain
EMK97_RS07940	COG1376	ErfK ybiS ycfS ynhG family protein
EMK97_RS07945	COG3025	triphosphatase activity
EMK97_RS07950	COG4991	sh3 domain protein
EMK97_RS07970	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EMK97_RS07975	COG0473	3-isopropylmalate dehydrogenase activity
EMK97_RS07980	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EMK97_RS07985	COG0066	3-isopropylmalate dehydratase activity
EMK97_RS07995	COG3409	Peptidoglycan-binding domain 1 protein
EMK97_RS07995	COG3267	Type II secretory pathway component ExeA
EMK97_RS08005	COG0617	tRNA 3'-terminal CCA addition
EMK97_RS08020	COG2203	Gaf domain
EMK97_RS08020	COG3706	GGDEF domain
EMK97_RS08020	COG4251	negative regulation of phosphorylation
EMK97_RS08020	COG5001	Diguanylate cyclase
EMK97_RS08040	COG2703	oxygen carrier activity
EMK97_RS08045	COG2703	oxygen carrier activity
EMK97_RS08075	COG0535	radical SAM domain protein
EMK97_RS08140	COG0848	biopolymer transport protein
EMK97_RS08145	COG0811	peptide transport
EMK97_RS08150	COG0811	peptide transport
EMK97_RS08160	COG0514	ATP-dependent DNA helicase (RecQ)
EMK97_RS08190	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EMK97_RS08190	COG0519	Catalyzes the synthesis of GMP from XMP
EMK97_RS08195	COG0516	GMP reductase activity
EMK97_RS08195	COG0517	IMP dehydrogenase activity
EMK97_RS08215	COG1160	GTP binding
EMK97_RS08220	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EMK97_RS08225	COG2976	Protein conserved in bacteria
EMK97_RS08230	COG0124	histidyl-tRNA synthetase
EMK97_RS08235	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EMK97_RS08240	COG1426	Protein conserved in bacteria
EMK97_RS08250	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EMK97_RS08255	COG0105	UTP biosynthetic process
EMK97_RS08265	COG0281	malic enzyme
EMK97_RS08270	COG2975	iron-sulfur cluster assembly
EMK97_RS08280	COG1522	sequence-specific DNA binding
EMK97_RS08285	COG0745	RESPONSE REGULATOR receiver
EMK97_RS08290	COG2205	protein histidine kinase activity
EMK97_RS08325	COG0443	Heat shock 70 kDa protein
EMK97_RS08335	COG0339	signal peptide processing
EMK97_RS08345	COG2205	protein histidine kinase activity
EMK97_RS08355	COG2204	response regulator
EMK97_RS08365	COG0583	DNA-binding transcription factor activity
EMK97_RS08370	COG3118	belongs to the thioredoxin family
EMK97_RS08380	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EMK97_RS08400	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EMK97_RS08420	COG3706	GGDEF domain
EMK97_RS08455	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EMK97_RS08460	COG1643	Atp-dependent helicase
EMK97_RS08465	COG1607	acyl-coa hydrolase
EMK97_RS08500	COG2200	EAL domain
EMK97_RS08500	COG2199	diguanylate cyclase activity
EMK97_RS08510	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EMK97_RS08515	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EMK97_RS08520	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EMK97_RS08525	COG0076	glutamate decarboxylase activity
EMK97_RS08535	COG4932	domain protein
EMK97_RS08535	COG5492	domain, Protein
EMK97_RS08540	COG0459	protein refolding
EMK97_RS08545	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EMK97_RS08555	COG1324	tolerance protein
EMK97_RS08560	COG4232	protein-disulfide reductase activity
EMK97_RS08585	COG0511	ligase activity, forming carbon-carbon bonds
EMK97_RS08590	COG0439	Biotin carboxylase
EMK97_RS08620	COG1566	PFAM secretion protein HlyD family protein
EMK97_RS08625	COG0625	glutathione transferase activity
EMK97_RS08635	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EMK97_RS08675	COG0629	single-stranded DNA binding
EMK97_RS08685	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EMK97_RS08695	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EMK97_RS08700	COG1902	pentaerythritol trinitrate reductase activity
EMK97_RS08700	COG0446	pyridine nucleotide-disulphide oxidoreductase
EMK97_RS08715	COG3360	Dodecin
EMK97_RS08720	COG2814	Major facilitator Superfamily
EMK97_RS08725	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EMK97_RS08760	COG0584	glycerophosphoryl diester phosphodiesterase
EMK97_RS08780	COG2188	Transcriptional regulator
EMK97_RS08785	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EMK97_RS08795	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EMK97_RS08805	COG0456	acetyltransferase
EMK97_RS08820	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EMK97_RS08825	COG0255	Belongs to the universal ribosomal protein uL29 family
EMK97_RS08830	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EMK97_RS08835	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EMK97_RS08840	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EMK97_RS08845	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EMK97_RS08850	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EMK97_RS08855	COG0089	rRNA binding
EMK97_RS08860	COG0088	Forms part of the polypeptide exit tunnel
EMK97_RS08865	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EMK97_RS08870	COG0051	transcription antitermination factor activity, RNA binding
EMK97_RS08875	COG1012	belongs to the aldehyde dehydrogenase family
EMK97_RS08880	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EMK97_RS08885	COG0604	alcohol dehydrogenase
EMK97_RS08890	COG1309	transcriptional regulator
EMK97_RS08900	COG0393	Putative heavy-metal-binding
EMK97_RS08905	COG0393	Putative heavy-metal-binding
EMK97_RS08910	COG0151	Belongs to the GarS family
EMK97_RS08920	COG0138	bifunctional purine biosynthesis protein purh
EMK97_RS08925	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
EMK97_RS08930	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EMK97_RS08980	COG5001	Diguanylate cyclase
EMK97_RS08980	COG5002	protein histidine kinase activity
EMK97_RS08980	COG3447	MASE1 domain protein
EMK97_RS08985	COG2264	protein methyltransferase activity
EMK97_RS08995	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EMK97_RS08995	COG1648	precorrin-2 dehydrogenase activity
EMK97_RS09005	COG3385	transposase activity
EMK97_RS09015	COG0564	pseudouridine synthase activity
EMK97_RS09055	COG2315	Protein conserved in bacteria
EMK97_RS09090	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EMK97_RS09105	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EMK97_RS09125	COG0338	D12 class N6 adenine-specific DNA methyltransferase
EMK97_RS09135	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EMK97_RS09140	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EMK97_RS09170	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EMK97_RS09175	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
EMK97_RS09175	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EMK97_RS09180	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
EMK97_RS09180	COG0165	Argininosuccinate lyase
EMK97_RS09185	COG0137	argininosuccinate synthase activity
EMK97_RS09190	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EMK97_RS09195	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EMK97_RS09220	COG0460	homoserine dehydrogenase
EMK97_RS09220	COG0527	aspartate kinase activity
EMK97_RS09225	COG0626	cystathionine gamma-synthase activity
EMK97_RS09230	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
EMK97_RS09245	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EMK97_RS09285	COG0545	Peptidyl-prolyl cis-trans isomerase
EMK97_RS09295	COG2900	Belongs to the SlyX family
EMK97_RS09300	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
EMK97_RS09305	COG0488	(ABC) transporter
EMK97_RS09325	COG0429	hydrolase of the alpha beta-hydrolase fold
EMK97_RS09345	COG0840	transmembrane signaling receptor activity
EMK97_RS09355	COG1218	3'(2'),5'-bisphosphate nucleotidase
EMK97_RS09360	COG0494	nUDIX hydrolase
EMK97_RS09365	COG1011	Hydrolase
EMK97_RS09375	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
EMK97_RS09385	COG3156	type II secretion system protein K
EMK97_RS09390	COG4795	General secretion pathway protein
EMK97_RS09395	COG2165	general secretion pathway protein
EMK97_RS09405	COG2165	general secretion pathway protein
EMK97_RS09410	COG1459	type II secretion system
EMK97_RS09415	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EMK97_RS09425	COG3031	protein transport across the cell outer membrane
EMK97_RS09430	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EMK97_RS09435	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EMK97_RS09440	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EMK97_RS09470	COG1940	carbohydrate kinase activity
EMK97_RS09480	COG0738	Major facilitator superfamily
EMK97_RS09485	COG4771	TonB-dependent receptor
EMK97_RS09495	COG0668	transmembrane transport
EMK97_RS09510	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
EMK97_RS09515	COG2814	Major facilitator Superfamily
EMK97_RS09520	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EMK97_RS09530	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
EMK97_RS09540	COG1227	inorganic diphosphatase activity
EMK97_RS09545	COG0183	Belongs to the thiolase family
EMK97_RS09550	COG1024	Enoyl-CoA hydratase
EMK97_RS09550	COG1250	3-hydroxyacyl-CoA dehydrogenase
EMK97_RS09560	COG3300	MHYT domain
EMK97_RS09560	COG5001	Diguanylate cyclase
EMK97_RS09580	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EMK97_RS09585	COG0741	lytic transglycosylase activity
EMK97_RS09605	COG1024	Enoyl-CoA hydratase
EMK97_RS09620	COG1842	Phage shock protein A
EMK97_RS09635	COG0582	viral genome integration into host DNA
EMK97_RS09640	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
EMK97_RS09680	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EMK97_RS09725	COG0735	belongs to the Fur family
EMK97_RS09735	COG0840	transmembrane signaling receptor activity
EMK97_RS09740	COG0163	prenyltransferase activity
EMK97_RS09745	COG0242	peptide deformylase activity
EMK97_RS09750	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EMK97_RS09765	COG0174	glutamine synthetase
EMK97_RS09775	COG3852	Histidine kinase
EMK97_RS09780	COG2204	response regulator
EMK97_RS09800	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
EMK97_RS09805	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EMK97_RS09810	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EMK97_RS09815	COG0049	tRNA binding
EMK97_RS09820	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EMK97_RS09825	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EMK97_RS09830	COG0085	RNA polymerase activity
EMK97_RS09840	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EMK97_RS09845	COG0081	regulation of translation
EMK97_RS09850	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EMK97_RS09855	COG0250	Participates in transcription elongation, termination and antitermination
EMK97_RS09860	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EMK97_RS09870	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EMK97_RS09900	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
EMK97_RS09900	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
EMK97_RS09910	COG1914	H( )-stimulated, divalent metal cation uptake system
EMK97_RS09915	COG1446	asparaginase
EMK97_RS09920	COG1757	Na H antiporter
EMK97_RS09950	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EMK97_RS09955	COG0348	domain, Protein
EMK97_RS09955	COG3901	Regulator of nitric oxide reductase transcription
EMK97_RS09965	COG0069	glutamate synthase activity
EMK97_RS10020	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EMK97_RS10030	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EMK97_RS10055	COG1917	Cupin 2, conserved barrel domain protein
EMK97_RS10055	COG4977	sequence-specific DNA binding
EMK97_RS10070	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EMK97_RS10085	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EMK97_RS10090	COG0786	glutamate:sodium symporter activity
EMK97_RS10110	COG0456	acetyltransferase
EMK97_RS10115	COG1506	peptidase
EMK97_RS10115	COG0823	Involved in the tonB-independent uptake of proteins
EMK97_RS10120	COG1054	Belongs to the UPF0176 family
EMK97_RS10135	COG3038	cytochrome b561
EMK97_RS10140	COG1049	propionate catabolic process, 2-methylcitrate cycle
EMK97_RS10160	COG3408	Glycogen debranching enzyme
EMK97_RS10160	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
EMK97_RS10180	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EMK97_RS10185	COG3250	beta-galactosidase activity
EMK97_RS10190	COG2186	Transcriptional regulator
EMK97_RS10205	COG2378	regulation of single-species biofilm formation
EMK97_RS10215	COG3291	Pkd domain containing protein
EMK97_RS10220	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EMK97_RS10230	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EMK97_RS10235	COG0508	dehydrogenase complex catalyzes the overall conversion of
EMK97_RS10240	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
EMK97_RS10245	COG2186	Transcriptional regulator
EMK97_RS10265	COG0157	Belongs to the NadC ModD family
EMK97_RS10275	COG1279	arginine transmembrane transporter activity
EMK97_RS10300	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
EMK97_RS10310	COG3530	Putative quorum-sensing-regulated virulence factor
EMK97_RS10315	COG3130	regulation of translation
EMK97_RS10335	COG3078	GTPase activator activity
EMK97_RS10345	COG1946	Acyl-CoA thioesterase
EMK97_RS10350	COG0668	transmembrane transport
EMK97_RS10355	COG0204	Acyl-transferase
EMK97_RS10360	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EMK97_RS10365	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EMK97_RS10375	COG1845	cytochrome c oxidase, subunit III
EMK97_RS10405	COG0730	response to heat
EMK97_RS10410	COG3123	guanosine phosphorylase activity
EMK97_RS10415	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EMK97_RS10420	COG0583	DNA-binding transcription factor activity
EMK97_RS10425	COG0606	chelatase, subunit chli
EMK97_RS10440	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EMK97_RS10445	COG0129	dihydroxy-acid dehydratase activity
EMK97_RS10450	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EMK97_RS10455	COG1959	2 iron, 2 sulfur cluster binding
EMK97_RS10465	COG3615	Tellurite resistance protein tehB
EMK97_RS10485	COG3485	protocatechuate 3,4-dioxygenase
EMK97_RS10510	COG1254	Belongs to the acylphosphatase family
EMK97_RS10590	COG3710	Transcriptional regulator
EMK97_RS10610	COG3550	peptidyl-serine autophosphorylation
EMK97_RS10645	COG2081	HI0933 family
EMK97_RS10655	COG0745	RESPONSE REGULATOR receiver
EMK97_RS10660	COG1528	Iron-storage protein
EMK97_RS10665	COG0742	ribosomal rna small subunit methyltransferase
EMK97_RS10690	COG2937	Belongs to the GPAT DAPAT family
EMK97_RS10705	COG2854	intermembrane phospholipid transfer
EMK97_RS10715	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EMK97_RS10725	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
EMK97_RS10730	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
EMK97_RS10735	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EMK97_RS10765	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EMK97_RS10770	COG1063	alcohol dehydrogenase
EMK97_RS10780	COG1522	sequence-specific DNA binding
EMK97_RS10790	COG1519	Transferase
EMK97_RS10795	COG3642	lipopolysaccharide core region biosynthetic process
EMK97_RS10815	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EMK97_RS10820	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EMK97_RS10845	COG1561	YicC-like family, N-terminal region
EMK97_RS10895	COG3132	Protein of unknown function, DUF480
EMK97_RS10900	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EMK97_RS10905	COG3706	GGDEF domain
EMK97_RS10910	COG4191	Histidine kinase
EMK97_RS10910	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EMK97_RS10920	COG4932	domain protein
EMK97_RS10920	COG5492	domain, Protein
EMK97_RS10970	COG1505	serine-type exopeptidase activity
EMK97_RS10990	COG0514	ATP-dependent DNA helicase (RecQ)
EMK97_RS10995	COG2050	protein possibly involved in aromatic compounds catabolism
EMK97_RS11020	COG2962	Rard protein
EMK97_RS11030	COG0210	DNA helicase
EMK97_RS11035	COG1011	Hydrolase
EMK97_RS11045	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EMK97_RS11055	COG1965	Belongs to the frataxin family
EMK97_RS11060	COG0181	hydroxymethylbilane synthase activity
EMK97_RS11065	COG1587	Uroporphyrinogen-III synthase
EMK97_RS11070	COG2959	enzyme of heme biosynthesis
EMK97_RS11075	COG3071	HemY protein
EMK97_RS11080	COG1025	Belongs to the peptidase M16 family
EMK97_RS11085	COG0300	oxidoreductase activity
EMK97_RS11095	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
EMK97_RS11105	COG3118	belongs to the thioredoxin family
EMK97_RS11115	COG0248	Ppx GppA phosphatase
EMK97_RS11150	COG0084	hydrolase, TatD family'
EMK97_RS11160	COG0805	protein transport
EMK97_RS11165	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EMK97_RS11170	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EMK97_RS11185	COG2177	Part of the ABC transporter FtsEX involved in
EMK97_RS11190	COG2884	Cell division ATP-binding protein ftsE
EMK97_RS11195	COG0552	protein localization to endoplasmic reticulum
EMK97_RS11200	COG0742	ribosomal rna small subunit methyltransferase
EMK97_RS11250	COG0589	response to stress
EMK97_RS11265	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EMK97_RS11270	COG1349	DNA-binding transcription factor activity
EMK97_RS11275	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EMK97_RS11295	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EMK97_RS11300	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EMK97_RS11305	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EMK97_RS11310	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EMK97_RS11315	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EMK97_RS11325	COG0356	it plays a direct role in the translocation of protons across the membrane
EMK97_RS11330	COG3312	ion transport
EMK97_RS11380	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EMK97_RS11400	COG2346	COG2346, Truncated hemoglobins
EMK97_RS11405	COG0408	coproporphyrinogen oxidase activity
EMK97_RS11415	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EMK97_RS11420	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EMK97_RS11425	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EMK97_RS11430	COG2922	Belongs to the Smg family
EMK97_RS11435	COG0758	DNA mediated transformation
EMK97_RS11445	COG0242	peptide deformylase activity
EMK97_RS11455	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EMK97_RS11455	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EMK97_RS11460	COG0569	domain protein
EMK97_RS11470	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EMK97_RS11475	COG1739	Uncharacterized protein family UPF0029
EMK97_RS11480	COG0006	proline dipeptidase activity
EMK97_RS11490	COG0425	Belongs to the sulfur carrier protein TusA family
EMK97_RS11505	COG0751	glycine-tRNA ligase activity
EMK97_RS11510	COG0752	glycyl-tRNA synthetase alpha subunit
EMK97_RS11515	COG0187	DNA topoisomerase II activity
EMK97_RS11530	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EMK97_RS11535	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EMK97_RS11540	COG0594	ribonuclease P activity
EMK97_RS11545	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EMK97_RS11550	COG0706	membrane insertase activity
EMK97_RS11555	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EMK97_RS11565	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EMK97_RS11570	COG0445	tRNA wobble uridine modification
EMK97_RS11575	COG0357	Ribosomal RNA small subunit methyltransferase G
EMK97_RS11580	COG1192	Involved in chromosome partitioning
EMK97_RS11585	COG1475	DNA binding
EMK97_RS11590	COG3293	Transposase
EMK97_RS11595	COG3385	transposase activity
EMK97_RS11615	COG0577	efflux transmembrane transporter activity
EMK97_RS11615	COG1136	(ABC) transporter
EMK97_RS11630	COG1131	(ABC) transporter
EMK97_RS11635	COG0842	Transport permease protein
EMK97_RS11645	COG3706	GGDEF domain
EMK97_RS11660	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EMK97_RS11670	COG2204	response regulator
EMK97_RS11675	COG3267	Type II secretory pathway component ExeA
EMK97_RS11675	COG3409	Peptidoglycan-binding domain 1 protein
EMK97_RS11685	COG0489	protein tyrosine kinase activity
EMK97_RS11700	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EMK97_RS11705	COG0726	polysaccharide deacetylase
EMK97_RS11715	COG0297	glycogen (starch) synthase activity
EMK97_RS11725	COG0438	transferase activity, transferring glycosyl groups
EMK97_RS11730	COG0367	asparagine synthase
EMK97_RS11735	COG0438	transferase activity, transferring glycosyl groups
EMK97_RS11795	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EMK97_RS11825	COG1696	Membrane protein involved in D-alanine export
EMK97_RS11850	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EMK97_RS11855	COG4206	TonB-dependent receptor
EMK97_RS11865	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EMK97_RS11880	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EMK97_RS11880	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EMK97_RS11890	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EMK97_RS11895	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EMK97_RS11905	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EMK97_RS11910	COG1758	RNA polymerase activity
EMK97_RS11915	COG0194	GDP metabolic process
EMK97_RS11920	COG1448	Aminotransferase
EMK97_RS11935	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EMK97_RS11945	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EMK97_RS11950	COG2183	response to ionizing radiation
EMK97_RS11955	COG0840	transmembrane signaling receptor activity
EMK97_RS11965	COG0840	transmembrane signaling receptor activity
EMK97_RS11970	COG0745	RESPONSE REGULATOR receiver
EMK97_RS11975	COG1027	Aspartate ammonia-lyase
EMK97_RS11980	COG0583	DNA-binding transcription factor activity
EMK97_RS11990	COG0823	Involved in the tonB-independent uptake of proteins
EMK97_RS11990	COG4946	Tricorn protease homolog
EMK97_RS11990	COG1506	peptidase
EMK97_RS12005	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EMK97_RS12025	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EMK97_RS12040	COG3201	nicotinamide mononucleotide transporter
EMK97_RS12100	COG3706	GGDEF domain
EMK97_RS12115	COG2195	Cleaves the N-terminal amino acid of tripeptides
EMK97_RS12120	COG1309	transcriptional regulator
EMK97_RS12125	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EMK97_RS12130	COG2003	Belongs to the UPF0758 family
EMK97_RS12150	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EMK97_RS12155	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EMK97_RS12165	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EMK97_RS12170	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EMK97_RS12205	COG0316	Belongs to the HesB IscA family
EMK97_RS12205	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EMK97_RS12225	COG0534	Mate efflux family protein
EMK97_RS12235	COG1999	signal sequence binding
EMK97_RS12240	COG0109	protoheme IX farnesyltransferase activity
EMK97_RS12265	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
EMK97_RS12270	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EMK97_RS12275	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EMK97_RS12280	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EMK97_RS12290	COG4771	TonB-dependent receptor
EMK97_RS12295	COG3385	transposase activity
EMK97_RS12340	COG0583	DNA-binding transcription factor activity
EMK97_RS12365	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EMK97_RS12380	COG2022	thiamine diphosphate biosynthetic process
EMK97_RS12395	COG1396	sequence-specific DNA binding
EMK97_RS12405	COG0095	Lipoate-protein ligase
EMK97_RS12425	COG3547	Transposase (IS116 IS110 IS902 family)
EMK97_RS12430	COG2116	formate transmembrane transporter activity
EMK97_RS12440	COG3008	intermembrane lipid transfer
EMK97_RS12445	COG2995	paraquat-inducible protein a
EMK97_RS12460	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EMK97_RS12535	COG0745	RESPONSE REGULATOR receiver
EMK97_RS12540	COG4771	TonB-dependent receptor
EMK97_RS12550	COG1280	lysine exporter protein (LysE YggA)
EMK97_RS12570	COG1309	transcriptional regulator
EMK97_RS12630	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EMK97_RS12640	COG3153	acetyltransferase
EMK97_RS12645	COG4771	TonB-dependent receptor
EMK97_RS12655	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EMK97_RS12670	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EMK97_RS12675	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EMK97_RS12685	COG2066	Belongs to the glutaminase family
EMK97_RS12710	COG1131	(ABC) transporter
EMK97_RS12725	COG2226	methyltransferase
EMK97_RS12735	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EMK97_RS12740	COG0210	DNA helicase
EMK97_RS12750	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EMK97_RS12775	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EMK97_RS12805	COG1683	Conserved Protein
EMK97_RS12820	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EMK97_RS12825	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EMK97_RS12825	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EMK97_RS12830	COG0802	atpase or kinase
EMK97_RS12835	COG0860	N-Acetylmuramoyl-L-alanine amidase
EMK97_RS12845	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EMK97_RS12850	COG1923	regulation of RNA biosynthetic process
EMK97_RS12855	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EMK97_RS12860	COG0330	HflC and HflK could
EMK97_RS12865	COG0330	HflC and HflK could
EMK97_RS12875	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EMK97_RS12885	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EMK97_RS12900	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EMK97_RS12910	COG0281	malic enzyme
EMK97_RS12945	COG1024	Enoyl-CoA hydratase
EMK97_RS12980	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EMK97_RS12990	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EMK97_RS12995	COG0315	cyclic pyranopterin monophosphate synthase activity
EMK97_RS13000	COG0521	Mo-molybdopterin cofactor biosynthetic process
EMK97_RS13005	COG0746	molybdenum cofactor guanylyltransferase activity
EMK97_RS13010	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EMK97_RS13025	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EMK97_RS13030	COG0540	Belongs to the ATCase OTCase family
EMK97_RS13040	COG1981	membrane
EMK97_RS13045	COG0038	chloride channel
EMK97_RS13055	COG0316	Belongs to the HesB IscA family
EMK97_RS13075	COG3706	GGDEF domain
EMK97_RS13085	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
EMK97_RS13090	COG0557	exoribonuclease II activity
EMK97_RS13095	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EMK97_RS13105	COG0360	Binds together with S18 to 16S ribosomal RNA
EMK97_RS13110	COG2965	DNA replication, synthesis of RNA primer
EMK97_RS13115	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EMK97_RS13120	COG0359	binds to the 23S rRNA
EMK97_RS13150	COG3267	Type II secretory pathway component ExeA
EMK97_RS13150	COG3409	Peptidoglycan-binding domain 1 protein
EMK97_RS13160	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EMK97_RS13165	COG1459	type II secretion system
EMK97_RS13175	COG2165	general secretion pathway protein
EMK97_RS13180	COG2165	general secretion pathway protein
EMK97_RS13210	COG1077	Cell shape determining protein MreB Mrl
EMK97_RS13215	COG1792	Involved in formation and maintenance of cell shape
EMK97_RS13220	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
EMK97_RS13230	COG1530	ribonuclease E activity
EMK97_RS13235	COG3164	Protein of unknown function
EMK97_RS13240	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EMK97_RS13245	COG0312	modulator of DNA gyrase
EMK97_RS13255	COG3028	Belongs to the UPF0307 family
EMK97_RS13260	COG0312	modulator of DNA gyrase
EMK97_RS13265	COG2239	Acts as a magnesium transporter
EMK97_RS13270	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EMK97_RS13275	COG1660	Displays ATPase and GTPase activities
EMK97_RS13290	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EMK97_RS13295	COG1137	ATPase activity
EMK97_RS13310	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EMK97_RS13315	COG0517	IMP dehydrogenase activity
EMK97_RS13315	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EMK97_RS13325	COG1127	ABC transporter
EMK97_RS13330	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EMK97_RS13335	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EMK97_RS13340	COG2854	intermembrane phospholipid transfer
EMK97_RS13350	COG5007	Belongs to the BolA IbaG family
EMK97_RS13355	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EMK97_RS13360	COG5212	phosphodiesterase
EMK97_RS13375	COG0318	PFAM AMP-dependent synthetase and ligase
EMK97_RS13390	COG2861	carbohydrate metabolic process
EMK97_RS13395	COG4942	peptidase
EMK97_RS13400	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EMK97_RS13410	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EMK97_RS13415	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
EMK97_RS13420	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EMK97_RS13425	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EMK97_RS13435	COG2267	carboxylic ester hydrolase activity
EMK97_RS13440	COG2205	protein histidine kinase activity
EMK97_RS13445	COG0745	RESPONSE REGULATOR receiver
EMK97_RS13450	COG3678	ATP-independent chaperone mediated protein folding
EMK97_RS13465	COG0688	phosphatidylethanolamine metabolic process
EMK97_RS13470	COG1162	GTPase activity
EMK97_RS13475	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
EMK97_RS13500	COG1506	peptidase
EMK97_RS13500	COG4946	Tricorn protease homolog
EMK97_RS13500	COG0823	Involved in the tonB-independent uptake of proteins
EMK97_RS13505	COG3385	transposase activity
EMK97_RS13525	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EMK97_RS13545	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EMK97_RS13550	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EMK97_RS13560	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EMK97_RS13565	COG0254	rRNA binding
EMK97_RS13590	COG0305	Participates in initiation and elongation during chromosome replication
EMK97_RS13605	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EMK97_RS13610	COG0346	lactoylglutathione lyase activity
EMK97_RS13620	COG4628	conserved protein (DUF2132)
EMK97_RS13625	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EMK97_RS13625	COG0678	peroxiredoxin activity
EMK97_RS13635	COG0402	S-adenosylhomocysteine deaminase activity
EMK97_RS13650	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EMK97_RS13655	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EMK97_RS13665	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EMK97_RS13675	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EMK97_RS13685	COG3118	belongs to the thioredoxin family
EMK97_RS13690	COG1968	undecaprenyl-diphosphatase activity
EMK97_RS13695	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EMK97_RS13700	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EMK97_RS13705	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EMK97_RS13710	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EMK97_RS13715	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EMK97_RS13720	COG1610	YqeY-like protein
EMK97_RS13725	COG0358	DNA primase activity
EMK97_RS13730	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EMK97_RS13795	COG1506	peptidase
EMK97_RS13795	COG0823	Involved in the tonB-independent uptake of proteins
EMK97_RS13800	COG1858	cytochrome C peroxidase
EMK97_RS13815	COG3909	cytochrome
EMK97_RS13870	COG2010	Cytochrome c
EMK97_RS13890	COG1217	gtp-binding protein TYPA
EMK97_RS13900	COG1295	ribonuclease BN
EMK97_RS13905	COG1490	D-aminoacyl-tRNA deacylase activity
EMK97_RS13910	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EMK97_RS13915	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EMK97_RS13920	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EMK97_RS13930	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EMK97_RS13935	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EMK97_RS13940	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EMK97_RS13945	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EMK97_RS13950	COG1841	ribosomal large subunit assembly
EMK97_RS13955	COG0200	Binds to the 23S rRNA
EMK97_RS13960	COG0201	protein transport
EMK97_RS13970	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EMK97_RS13975	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EMK97_RS13980	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EMK97_RS13985	COG0202	RNA polymerase activity
EMK97_RS13990	COG0203	ribosomal protein L17
EMK97_RS13995	COG3954	Phosphoribulokinase
EMK97_RS14010	COG1765	OsmC-like protein
EMK97_RS14020	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EMK97_RS14025	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EMK97_RS14030	COG2988	succinylglutamate desuccinylase activity
EMK97_RS14035	COG1012	belongs to the aldehyde dehydrogenase family
EMK97_RS14045	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EMK97_RS14065	COG3706	GGDEF domain
EMK97_RS14070	COG0347	Belongs to the P(II) protein family
EMK97_RS14075	COG0004	ammonium transporteR
EMK97_RS14085	COG0784	Response regulator, receiver
EMK97_RS14085	COG2205	protein histidine kinase activity
EMK97_RS14095	COG2837	iron assimilation
EMK97_RS14105	COG1960	acyl-CoA dehydrogenase activity
EMK97_RS14110	COG2001	Belongs to the MraZ family
EMK97_RS14115	COG0275	rRNA processing
EMK97_RS14120	COG3116	cell division
EMK97_RS14125	COG0768	penicillin binding
EMK97_RS14135	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EMK97_RS14140	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EMK97_RS14150	COG0772	Belongs to the SEDS family
EMK97_RS14160	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EMK97_RS14170	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EMK97_RS14175	COG0849	cell division
EMK97_RS14180	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EMK97_RS14185	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
EMK97_RS14195	COG0739	heme binding
EMK97_RS14200	COG0653	protein targeting
EMK97_RS14225	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EMK97_RS14230	COG1459	type II secretion system
EMK97_RS14235	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EMK97_RS14240	COG4969	Belongs to the N-Me-Phe pilin family
EMK97_RS14250	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EMK97_RS14255	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EMK97_RS14260	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EMK97_RS14265	COG0723	plastoquinol--plastocyanin reductase activity
EMK97_RS14270	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EMK97_RS14275	COG2857	Cytochrome c1
EMK97_RS14280	COG0625	glutathione transferase activity
EMK97_RS14285	COG2969	positive regulation of protein catabolic process
EMK97_RS14290	COG2823	Periplasmic or secreted lipoprotein
EMK97_RS14295	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
EMK97_RS14310	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EMK97_RS14320	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
EMK97_RS14330	COG1846	Transcriptional regulator
EMK97_RS14360	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EMK97_RS14365	COG2986	histidine ammonia-lyase
EMK97_RS14415	COG0523	cobalamin synthesis protein
EMK97_RS14445	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EMK97_RS14455	COG2205	protein histidine kinase activity
EMK97_RS14455	COG0784	Response regulator, receiver
EMK97_RS14465	COG3706	GGDEF domain
EMK97_RS14475	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EMK97_RS14490	COG0668	transmembrane transport
EMK97_RS14505	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EMK97_RS14530	COG1501	Belongs to the glycosyl hydrolase 31 family
EMK97_RS14535	COG0366	Alpha amylase catalytic
EMK97_RS14565	COG4989	oxidoreductase activity
EMK97_RS14600	COG0515	serine threonine protein kinase
EMK97_RS14600	COG2815	serine threonine protein kinase
EMK97_RS14640	COG1136	(ABC) transporter
EMK97_RS14640	COG0577	efflux transmembrane transporter activity
EMK97_RS14655	COG3394	polysaccharide catabolic process
EMK97_RS14660	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EMK97_RS14670	COG1131	(ABC) transporter
EMK97_RS14675	COG0842	Transport permease protein
EMK97_RS14680	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EMK97_RS14720	COG4628	conserved protein (DUF2132)
EMK97_RS14730	COG0784	Response regulator, receiver
EMK97_RS14740	COG1733	regulation of RNA biosynthetic process
EMK97_RS14745	COG2249	NAD(P)H dehydrogenase (quinone) activity
EMK97_RS14830	COG0823	Involved in the tonB-independent uptake of proteins
EMK97_RS14840	COG0454	-acetyltransferase
EMK97_RS14860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EMK97_RS14860	COG4191	Histidine kinase
EMK97_RS14865	COG2204	response regulator
EMK97_RS14875	COG0577	efflux transmembrane transporter activity
EMK97_RS14875	COG1136	(ABC) transporter
EMK97_RS14885	COG1785	Belongs to the alkaline phosphatase family
EMK97_RS14890	COG1785	Belongs to the alkaline phosphatase family
EMK97_RS14915	COG5001	Diguanylate cyclase
EMK97_RS14915	COG1716	ATPase activity
EMK97_RS14940	COG5001	Diguanylate cyclase
EMK97_RS14940	COG3300	MHYT domain
EMK97_RS14945	COG0506	proline dehydrogenase activity
EMK97_RS14945	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EMK97_RS14945	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EMK97_RS14960	COG0733	neurotransmitter:sodium symporter activity
EMK97_RS14965	COG5001	Diguanylate cyclase
EMK97_RS14965	COG3300	MHYT domain
EMK97_RS14970	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EMK97_RS14970	COG0116	Belongs to the methyltransferase superfamily
EMK97_RS14975	COG1793	dna ligase
EMK97_RS14990	COG2827	Endonuclease containing a URI domain
EMK97_RS15015	COG1278	Cold shock
EMK97_RS15030	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EMK97_RS15035	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EMK97_RS15040	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EMK97_RS15045	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
EMK97_RS15050	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
EMK97_RS15065	COG0564	pseudouridine synthase activity
EMK97_RS15070	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EMK97_RS15075	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EMK97_RS15085	COG3293	Transposase
EMK97_RS15100	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EMK97_RS15130	COG0784	Response regulator, receiver
EMK97_RS15130	COG2205	protein histidine kinase activity
EMK97_RS15130	COG5002	protein histidine kinase activity
EMK97_RS15135	COG1438	arginine binding
EMK97_RS15140	COG0039	L-malate dehydrogenase activity
EMK97_RS15150	COG0142	geranyltranstransferase activity
EMK97_RS15155	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EMK97_RS15160	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EMK97_RS15165	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EMK97_RS15175	COG0493	'glutamate synthase
EMK97_RS15180	COG0070	glutamate synthase
EMK97_RS15180	COG0067	glutamate synthase
EMK97_RS15180	COG0069	glutamate synthase activity
EMK97_RS15185	COG1469	GTP cyclohydrolase I activity
EMK97_RS15195	COG0745	RESPONSE REGULATOR receiver
EMK97_RS15200	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EMK97_RS15200	COG4191	Histidine kinase
EMK97_RS15210	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EMK97_RS15220	COG0019	diaminopimelate decarboxylase activity
EMK97_RS15230	COG3385	transposase activity
EMK97_RS15245	COG4771	TonB-dependent receptor
EMK97_RS15255	COG2996	Protein conserved in bacteria
EMK97_RS15285	COG2995	paraquat-inducible protein a
EMK97_RS15290	COG2207	Transcriptional regulator
EMK97_RS15325	COG1902	pentaerythritol trinitrate reductase activity
EMK97_RS15325	COG0446	pyridine nucleotide-disulphide oxidoreductase
EMK97_RS15330	COG1131	(ABC) transporter
EMK97_RS15345	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EMK97_RS15360	COG0028	Belongs to the TPP enzyme family
EMK97_RS15365	COG2258	MOSC domain
EMK97_RS15370	COG3706	GGDEF domain
EMK97_RS15400	COG0471	metal ion transport
EMK97_RS15425	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EMK97_RS15430	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EMK97_RS15445	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EMK97_RS15450	COG0463	Glycosyl transferase, family 2
EMK97_RS15460	COG2986	histidine ammonia-lyase
EMK97_RS15485	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EMK97_RS15495	COG1028	Short-chain dehydrogenase reductase Sdr
EMK97_RS15510	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EMK97_RS15525	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EMK97_RS15530	COG0205	6-phosphofructokinase activity
EMK97_RS15540	COG2205	protein histidine kinase activity
EMK97_RS15545	COG0745	RESPONSE REGULATOR receiver
EMK97_RS15565	COG1960	acyl-CoA dehydrogenase activity
EMK97_RS15575	COG2226	methyltransferase
EMK97_RS15605	COG1438	arginine binding
EMK97_RS15625	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EMK97_RS15635	COG2885	chlorophyll binding
EMK97_RS15645	COG5001	Diguanylate cyclase
EMK97_RS15645	COG5002	protein histidine kinase activity
EMK97_RS15665	COG0179	Fumarylacetoacetate (FAA) hydrolase
EMK97_RS15670	COG3112	Uncharacterised protein family (UPF0231)
EMK97_RS15680	COG2814	Major facilitator Superfamily
EMK97_RS15705	COG0271	Belongs to the BolA IbaG family
EMK97_RS15710	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EMK97_RS15720	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
EMK97_RS15725	COG1805	sodium ion transport
EMK97_RS15730	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
EMK97_RS15735	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
EMK97_RS15740	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
EMK97_RS15745	COG2871	sodium ion transport
EMK97_RS15750	COG1477	protein flavinylation
EMK97_RS15760	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EMK97_RS15765	COG0142	geranyltranstransferase activity
EMK97_RS15770	COG1722	exodeoxyribonuclease VII activity
EMK97_RS15775	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EMK97_RS15785	COG0301	tRNA thio-modification
EMK97_RS15785	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EMK97_RS15790	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EMK97_RS15800	COG1666	GTP binding
EMK97_RS15815	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
EMK97_RS15825	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EMK97_RS15830	COG1595	DNA-templated transcription, initiation
EMK97_RS15850	COG0481	GTPase activity
EMK97_RS15855	COG0681	Belongs to the peptidase S26 family
EMK97_RS15860	COG0571	ribonuclease III activity
EMK97_RS15865	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EMK97_RS15870	COG1381	Involved in DNA repair and RecF pathway recombination
EMK97_RS15875	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EMK97_RS15890	COG2205	protein histidine kinase activity
EMK97_RS15890	COG3437	response regulator, receiver
EMK97_RS15890	COG3850	Histidine kinase
EMK97_RS15890	COG4999	Histidine kinase
EMK97_RS15900	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EMK97_RS15905	COG3956	TIGRFAM MazG family protein
EMK97_RS15915	COG2832	Protein of unknown function (DUF454)
EMK97_RS15925	COG0504	CTP synthase activity
EMK97_RS15945	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EMK97_RS15950	COG3022	response to hydroperoxide
EMK97_RS15975	COG0513	Belongs to the DEAD box helicase family
EMK97_RS15985	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EMK97_RS16000	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EMK97_RS16005	COG0733	neurotransmitter:sodium symporter activity
EMK97_RS16010	COG0564	pseudouridine synthase activity
EMK97_RS16015	COG0612	Peptidase, M16
EMK97_RS16020	COG2918	glutathione biosynthetic process
EMK97_RS16040	COG4536	flavin adenine dinucleotide binding
EMK97_RS16045	COG4137	Cytochrome C assembly protein
EMK97_RS16050	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EMK97_RS16075	COG0228	four-way junction DNA binding
EMK97_RS16080	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EMK97_RS16085	COG0336	Belongs to the RNA methyltransferase TrmD family
EMK97_RS16090	COG0335	large ribosomal subunit rRNA binding
EMK97_RS16135	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EMK97_RS16145	COG0811	peptide transport
EMK97_RS16150	COG0811	peptide transport
EMK97_RS16155	COG0848	biopolymer transport protein
EMK97_RS16250	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EMK97_RS16255	COG3385	transposase activity
EMK97_RS16265	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EMK97_RS16270	COG0287	Prephenate dehydrogenase
EMK97_RS16270	COG1605	Chorismate mutase
EMK97_RS16280	COG3590	peptidase
EMK97_RS16290	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EMK97_RS16300	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EMK97_RS16300	COG2146	nitrite reductase [NAD(P)H] activity
EMK97_RS16310	COG2223	nitrite transmembrane transporter activity
EMK97_RS16315	COG2815	serine threonine protein kinase
EMK97_RS16315	COG0515	serine threonine protein kinase
EMK97_RS16320	COG0243	molybdopterin cofactor binding
EMK97_RS16350	COG2176	DNA-directed DNA polymerase activity
EMK97_RS16360	COG3038	cytochrome b561
EMK97_RS16395	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EMK97_RS16400	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EMK97_RS16405	COG3713	MltA-interacting MipA family protein
EMK97_RS16415	COG0077	Prephenate dehydratase
EMK97_RS16415	COG1605	Chorismate mutase
EMK97_RS16435	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EMK97_RS16440	COG1346	cytolysis
EMK97_RS16460	COG5002	protein histidine kinase activity
EMK97_RS16460	COG5001	Diguanylate cyclase
EMK97_RS16510	COG0640	Transcriptional regulator
EMK97_RS16530	COG0019	diaminopimelate decarboxylase activity
EMK97_RS16550	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EMK97_RS16560	COG0189	ligase activity
EMK97_RS16565	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EMK97_RS16570	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EMK97_RS16575	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EMK97_RS16595	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EMK97_RS16600	COG3079	Belongs to the UPF0149 family
EMK97_RS16605	COG0006	proline dipeptidase activity
EMK97_RS16610	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EMK97_RS16615	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EMK97_RS16620	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EMK97_RS16630	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EMK97_RS16630	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EMK97_RS16675	COG1401	restriction endodeoxyribonuclease activity
EMK97_RS16730	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EMK97_RS16750	COG1228	amidohydrolase
EMK97_RS16795	COG0583	DNA-binding transcription factor activity
EMK97_RS16800	COG0730	response to heat
EMK97_RS16830	COG1902	pentaerythritol trinitrate reductase activity
EMK97_RS16835	COG1119	ATPase activity
EMK97_RS16845	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EMK97_RS16850	COG0590	tRNA wobble adenosine to inosine editing
EMK97_RS16875	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EMK97_RS16880	COG0302	gtp cyclohydrolase
EMK97_RS16895	COG2824	Alkylphosphonate utilization operon protein PhnA
EMK97_RS16900	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EMK97_RS16935	COG3228	Belongs to the MtfA family
EMK97_RS16955	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
EMK97_RS16965	COG1595	DNA-templated transcription, initiation
EMK97_RS16970	COG3806	Anti-sigma factor
EMK97_RS16980	COG0415	Belongs to the DNA photolyase family
EMK97_RS17005	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EMK97_RS17015	COG0435	Glutathione S-transferase
EMK97_RS17020	COG2259	Doxx family
EMK97_RS17025	COG0583	DNA-binding transcription factor activity
EMK97_RS17030	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EMK97_RS17045	COG2207	Transcriptional regulator
EMK97_RS17050	COG1979	alcohol dehydrogenase
EMK97_RS17055	COG0640	Transcriptional regulator
EMK97_RS17060	COG0798	PFAM Bile acid sodium symporter
EMK97_RS17065	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EMK97_RS17095	COG2133	pyrroloquinoline quinone binding
EMK97_RS17105	COG1944	ATP diphosphatase activity
EMK97_RS17150	COG0668	transmembrane transport
EMK97_RS17175	COG0745	RESPONSE REGULATOR receiver
EMK97_RS17200	COG3590	peptidase
EMK97_RS17210	COG4771	TonB-dependent receptor
EMK97_RS17280	COG1131	(ABC) transporter
EMK97_RS17310	COG0667	Aldo Keto reductase
EMK97_RS17325	COG0840	transmembrane signaling receptor activity
EMK97_RS17335	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EMK97_RS17345	COG3385	transposase activity
EMK97_RS17365	COG0583	DNA-binding transcription factor activity
EMK97_RS17375	COG0789	Transcriptional regulator
EMK97_RS17380	COG0701	Predicted permease
EMK97_RS17395	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EMK97_RS17400	COG2867	negative regulation of translational initiation
EMK97_RS17405	COG2914	Belongs to the UPF0125 (RnfH) family
EMK97_RS17415	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EMK97_RS17420	COG0497	DNA recombination
EMK97_RS17425	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EMK97_RS17430	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EMK97_RS17440	COG0443	Heat shock 70 kDa protein
EMK97_RS17445	COG0484	heat shock protein binding
EMK97_RS17455	COG2111	Na H antiporter
EMK97_RS17455	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EMK97_RS17460	COG1006	Multisubunit Na H antiporter MnhC subunit
EMK97_RS17465	COG0651	ATP synthesis coupled electron transport
EMK97_RS17470	COG1863	multisubunit Na H antiporter MnhE subunit
EMK97_RS17475	COG2212	antiporter activity
EMK97_RS17485	COG1320	monovalent cation:proton antiporter activity
EMK97_RS17490	COG3101	peptidyl-lysine hydroxylation
EMK97_RS17510	COG1879	ABC-type sugar transport system periplasmic component
EMK97_RS17525	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EMK97_RS17530	COG3385	transposase activity
EMK97_RS17540	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EMK97_RS17550	COG0101	tRNA pseudouridine synthase activity
EMK97_RS17555	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EMK97_RS17560	COG0285	dihydrofolate synthase activity
EMK97_RS17570	COG1286	toxin biosynthetic process
EMK97_RS17575	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EMK97_RS17600	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EMK97_RS17605	COG0215	cysteine-tRNA ligase activity
EMK97_RS17610	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EMK97_RS17635	COG0544	peptidyl-prolyl cis-trans isomerase activity
EMK97_RS17640	COG0740	serine-type endopeptidase activity
EMK97_RS17645	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EMK97_RS17650	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EMK97_RS17660	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EMK97_RS17665	COG3385	transposase activity
EMK97_RS17670	COG4172	Belongs to the ABC transporter superfamily
EMK97_RS17675	COG4172	Belongs to the ABC transporter superfamily
EMK97_RS17680	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EMK97_RS17685	COG4168	peptide transport system, permease
EMK97_RS17690	COG0747	negative chemotaxis
EMK97_RS17695	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EMK97_RS17700	COG1842	Phage shock protein A
EMK97_RS17715	COG3106	COG3106 Predicted ATPase
EMK97_RS17720	COG3768	UPF0283 membrane protein
EMK97_RS17730	COG2154	pterin-4-alpha-carbinolamine dehydratase
EMK97_RS17745	COG0625	glutathione transferase activity
EMK97_RS17775	COG0457	Tetratricopeptide repeat
EMK97_RS17785	COG0811	peptide transport
EMK97_RS17790	COG0811	peptide transport
EMK97_RS17795	COG0848	biopolymer transport protein
EMK97_RS17830	COG0745	RESPONSE REGULATOR receiver
EMK97_RS17835	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EMK97_RS17840	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EMK97_RS17845	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EMK97_RS17850	COG0023	Translation Initiation Factor
EMK97_RS17900	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EMK97_RS17905	COG0564	pseudouridine synthase activity
EMK97_RS17925	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EMK97_RS17925	COG0047	phosphoribosylformylglycinamidine synthase activity
EMK97_RS17930	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
EMK97_RS17935	COG0784	Response regulator, receiver
EMK97_RS17935	COG5002	protein histidine kinase activity
EMK97_RS17935	COG2205	protein histidine kinase activity
EMK97_RS17940	COG0590	tRNA wobble adenosine to inosine editing
EMK97_RS17945	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EMK97_RS17950	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EMK97_RS17960	COG0762	integral membrane protein
EMK97_RS17965	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EMK97_RS17970	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EMK97_RS17985	COG0517	IMP dehydrogenase activity
EMK97_RS17985	COG0516	GMP reductase activity
EMK97_RS17995	COG0573	inorganic phosphate transmembrane transporter activity
EMK97_RS18000	COG0573	inorganic phosphate transmembrane transporter activity
EMK97_RS18005	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EMK97_RS18010	COG0704	Plays a role in the regulation of phosphate uptake
EMK97_RS18015	COG1392	Phosphate transport regulator
EMK97_RS18020	COG0306	phosphate transporter
EMK97_RS18025	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EMK97_RS18030	COG0583	DNA-binding transcription factor activity
EMK97_RS18035	COG3122	Protein conserved in bacteria
EMK97_RS18045	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EMK97_RS18070	COG1752	Esterase of the alpha-beta hydrolase superfamily
EMK97_RS18075	COG0676	glucose-6-phosphate 1-epimerase activity
EMK97_RS18080	COG3066	DNA modification
EMK97_RS18085	COG0494	nUDIX hydrolase
EMK97_RS18095	COG0730	response to heat
EMK97_RS18100	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EMK97_RS18105	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EMK97_RS18120	COG0583	DNA-binding transcription factor activity
EMK97_RS18130	COG2015	COG2015, Alkyl sulfatase and related hydrolases
EMK97_RS18135	COG3634	alkyl hydroperoxide reductase activity
EMK97_RS18155	COG4771	TonB-dependent receptor
EMK97_RS18170	COG1429	ligase activity, forming nitrogen-metal bonds
EMK97_RS18180	COG4772	TonB-dependent receptor
EMK97_RS18185	COG1760	l-serine dehydratase
EMK97_RS18190	COG0494	nUDIX hydrolase
EMK97_RS18195	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EMK97_RS18200	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EMK97_RS18200	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
EMK97_RS18225	COG0583	DNA-binding transcription factor activity
EMK97_RS18245	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EMK97_RS18250	COG0583	DNA-binding transcription factor activity
EMK97_RS18255	COG3038	cytochrome b561
EMK97_RS18280	COG0183	Belongs to the thiolase family
EMK97_RS18285	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EMK97_RS18290	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EMK97_RS18300	COG1414	Transcriptional regulator
EMK97_RS18320	COG0733	neurotransmitter:sodium symporter activity
EMK97_RS18325	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EMK97_RS18340	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EMK97_RS18345	COG1671	Belongs to the UPF0178 family
EMK97_RS18360	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EMK97_RS18365	COG0071	Belongs to the small heat shock protein (HSP20) family
EMK97_RS18370	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EMK97_RS18380	COG3706	GGDEF domain
EMK97_RS18385	COG0815	Transfers the fatty acyl group on membrane lipoproteins
EMK97_RS18390	COG4535	Mg2 and Co2 transporter CorC
EMK97_RS18400	COG1702	phosphate starvation-inducible protein PhoH
EMK97_RS18405	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EMK97_RS18410	COG3300	MHYT domain
EMK97_RS18410	COG5001	Diguanylate cyclase
EMK97_RS18415	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EMK97_RS18460	COG0193	aminoacyl-tRNA hydrolase activity
EMK97_RS18465	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EMK97_RS18470	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EMK97_RS18480	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
EMK97_RS18485	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EMK97_RS18490	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EMK97_RS18495	COG2890	protein-(glutamine-N5) methyltransferase activity
EMK97_RS18505	COG2912	Transglutaminase-like superfamily
EMK97_RS18515	COG2877	3-deoxy-8-phosphooctulonate synthase activity
EMK97_RS18525	COG0583	DNA-binding transcription factor activity
EMK97_RS18535	COG2363	Small membrane protein
EMK97_RS18540	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
EMK97_RS18545	COG0473	3-isopropylmalate dehydrogenase activity
EMK97_RS18555	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EMK97_RS18560	COG1611	Belongs to the LOG family
EMK97_RS18565	COG3706	GGDEF domain
EMK97_RS18600	COG1404	Belongs to the peptidase S8 family
EMK97_RS18610	COG1404	Belongs to the peptidase S8 family
EMK97_RS18615	COG3292	Two component regulator propeller
EMK97_RS18615	COG2205	protein histidine kinase activity
EMK97_RS18615	COG0745	RESPONSE REGULATOR receiver
EMK97_RS18620	COG0745	RESPONSE REGULATOR receiver
EMK97_RS18620	COG2205	protein histidine kinase activity
EMK97_RS18620	COG3292	Two component regulator propeller
EMK97_RS18630	COG3291	Pkd domain containing protein
EMK97_RS18640	COG0159	tryptophan synthase activity
EMK97_RS18650	COG0135	phosphoribosylanthranilate isomerase activity
EMK97_RS18650	COG0134	indole-3-glycerol-phosphate synthase activity
EMK97_RS18660	COG0512	Glutamine amidotransferase of anthranilate synthase
EMK97_RS18665	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EMK97_RS18675	COG0009	L-threonylcarbamoyladenylate synthase
EMK97_RS18680	COG1187	pseudouridine synthase activity
EMK97_RS18685	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
EMK97_RS18695	COG2951	lytic endotransglycosylase activity
EMK97_RS18700	COG2983	Belongs to the UPF0260 family
EMK97_RS18715	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EMK97_RS18720	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
EMK97_RS18725	COG3682	Transcriptional regulator
EMK97_RS18735	COG0513	Belongs to the DEAD box helicase family
EMK97_RS18745	COG3706	GGDEF domain
EMK97_RS18765	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EMK97_RS18770	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EMK97_RS18780	COG4770	biotin carboxylase activity
EMK97_RS18785	COG1024	Enoyl-CoA hydratase
EMK97_RS18790	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EMK97_RS18795	COG1960	acyl-CoA dehydrogenase activity
EMK97_RS18805	COG0183	Belongs to the thiolase family
EMK97_RS18810	COG1960	acyl-CoA dehydrogenase activity
EMK97_RS18815	COG1024	Enoyl-CoA hydratase
EMK97_RS18820	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EMK97_RS18830	COG1028	Short-chain dehydrogenase reductase Sdr
EMK97_RS18860	COG0534	Mate efflux family protein
EMK97_RS18865	COG1309	transcriptional regulator
EMK97_RS18885	COG0123	including yeast histone deacetylase and acetoin utilization protein
EMK97_RS18890	COG0427	acetyl-CoA hydrolase
EMK97_RS18905	COG0110	maltose O-acetyltransferase activity
EMK97_RS18935	COG0328	RNA-DNA hybrid ribonuclease activity