locus-tag	class	description
AYR55_RS00005	COG3404	Formiminotransferase-cyclodeaminase
AYR55_RS00015	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AYR55_RS00020	COG0248	Ppx GppA phosphatase
AYR55_RS00020	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AYR55_RS00025	COG1126	abc transporter atp-binding protein
AYR55_RS00030	COG0765	amino acid transport
AYR55_RS00035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AYR55_RS00070	COG0454	-acetyltransferase
AYR55_RS00075	COG1114	Component of the transport system for branched-chain amino acids
AYR55_RS00080	COG0697	spore germination
AYR55_RS00095	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AYR55_RS00125	COG0561	phosphatase activity
AYR55_RS00145	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AYR55_RS00145	COG0512	Glutamine amidotransferase of anthranilate synthase
AYR55_RS00170	COG0159	tryptophan synthase activity
AYR55_RS00175	COG0398	Pfam SNARE associated Golgi protein
AYR55_RS00185	COG0626	cystathionine gamma-synthase activity
AYR55_RS00200	COG3328	transposase activity
AYR55_RS00210	COG3118	belongs to the thioredoxin family
AYR55_RS00220	COG0745	RESPONSE REGULATOR receiver
AYR55_RS00225	COG5002	protein histidine kinase activity
AYR55_RS00240	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AYR55_RS00245	COG1696	Membrane protein involved in D-alanine export
AYR55_RS00250	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AYR55_RS00255	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
AYR55_RS00265	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AYR55_RS00275	COG3328	transposase activity
AYR55_RS00280	COG0586	Pfam SNARE associated Golgi protein
AYR55_RS00330	COG0791	NLP P60 protein
AYR55_RS00350	COG1074	ATP-dependent DNA helicase activity
AYR55_RS00375	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AYR55_RS00395	COG4932	domain protein
AYR55_RS00395	COG4886	Leucine-rich repeat (LRR) protein
AYR55_RS00400	COG0765	amino acid transport
AYR55_RS00410	COG2213	PTS system mannitol-specific
AYR55_RS00420	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AYR55_RS00430	COG0745	RESPONSE REGULATOR receiver
AYR55_RS00440	COG1686	Belongs to the peptidase S11 family
AYR55_RS00445	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AYR55_RS00455	COG1794	racemase activity, acting on amino acids and derivatives
AYR55_RS00465	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AYR55_RS00485	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AYR55_RS00505	COG0628	permease
AYR55_RS00510	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AYR55_RS00520	COG0588	phosphoglycerate mutase activity
AYR55_RS00535	COG1309	transcriptional regulator
AYR55_RS00560	COG1309	transcriptional regulator
AYR55_RS00565	COG4372	Transposase
AYR55_RS00590	COG1882	Formate acetyltransferase
AYR55_RS00595	COG1349	DNA-binding transcription factor activity
AYR55_RS00600	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AYR55_RS00655	COG0477	Major facilitator Superfamily
AYR55_RS00660	COG1131	(ABC) transporter
AYR55_RS00670	COG1309	transcriptional regulator
AYR55_RS00695	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AYR55_RS00715	COG0789	Transcriptional regulator
AYR55_RS00720	COG1902	pentaerythritol trinitrate reductase activity
AYR55_RS00725	COG0583	DNA-binding transcription factor activity
AYR55_RS00730	COG0281	malic enzyme
AYR55_RS00745	COG1136	(ABC) transporter
AYR55_RS00750	COG0577	efflux transmembrane transporter activity
AYR55_RS00775	COG2233	PERMEase
AYR55_RS00790	COG4221	oxidoreductase activity
AYR55_RS00805	COG0789	Transcriptional regulator
AYR55_RS00815	COG1335	isochorismatase
AYR55_RS00825	COG1937	Protein conserved in bacteria
AYR55_RS00830	COG0546	phosphoglycolate phosphatase activity
AYR55_RS00845	COG0702	epimerase
AYR55_RS00855	COG4372	Transposase
AYR55_RS00875	COG0860	N-Acetylmuramoyl-L-alanine amidase
AYR55_RS00880	COG5002	protein histidine kinase activity
AYR55_RS00890	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AYR55_RS00895	COG0463	Glycosyl transferase, family 2
AYR55_RS00905	COG4585	Histidine kinase
AYR55_RS00910	COG2197	response regulator
AYR55_RS00930	COG0024	Methionine aminopeptidase
AYR55_RS00965	COG1216	Glycosyl transferase, family 2
AYR55_RS00995	COG0438	transferase activity, transferring glycosyl groups
AYR55_RS01000	COG2368	4-hydroxyphenylacetate
AYR55_RS01005	COG0516	GMP reductase activity
AYR55_RS01015	COG1546	Belongs to the CinA family
AYR55_RS01015	COG1058	Belongs to the CinA family
AYR55_RS01045	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AYR55_RS01050	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AYR55_RS01055	COG0148	phosphopyruvate hydratase activity
AYR55_RS01060	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AYR55_RS01085	COG0735	belongs to the Fur family
AYR55_RS01100	COG0436	Aminotransferase
AYR55_RS01105	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AYR55_RS01115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AYR55_RS01120	COG0765	amino acid transport
AYR55_RS01125	COG0765	amino acid transport
AYR55_RS01135	COG0531	amino acid
AYR55_RS01140	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
AYR55_RS01145	COG0531	amino acid
AYR55_RS01155	COG0039	L-malate dehydrogenase activity
AYR55_RS01160	COG0193	aminoacyl-tRNA hydrolase activity
AYR55_RS01165	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AYR55_RS01170	COG2244	polysaccharide biosynthetic process
AYR55_RS01175	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AYR55_RS01185	COG1098	S1 RNA binding domain
AYR55_RS01190	COG0037	tRNA processing
AYR55_RS01205	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AYR55_RS01210	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AYR55_RS01215	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AYR55_RS01245	COG3104	oligopeptide transport
AYR55_RS01270	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AYR55_RS01275	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AYR55_RS01280	COG2188	Transcriptional regulator
AYR55_RS01285	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AYR55_RS01290	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
AYR55_RS01300	COG1091	dTDP-4-dehydrorhamnose reductase activity
AYR55_RS01310	COG0463	Glycosyl transferase, family 2
AYR55_RS01330	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AYR55_RS01335	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AYR55_RS01355	COG4120	Belongs to the binding-protein-dependent transport system permease family
AYR55_RS01360	COG1122	ATPase activity
AYR55_RS01365	COG2183	response to ionizing radiation
AYR55_RS01370	COG3091	SprT-like family
AYR55_RS01375	COG0460	homoserine dehydrogenase
AYR55_RS01390	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AYR55_RS01390	COG3933	PFAM sigma-54 factor interaction domain-containing protein
AYR55_RS01400	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AYR55_RS01400	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AYR55_RS01410	COG3715	PTS system
AYR55_RS01415	COG3716	PTS system mannose fructose sorbose family IID component
AYR55_RS01435	COG4372	Transposase
AYR55_RS01455	COG0025	NhaP-type Na H and K H
AYR55_RS01460	COG1271	oxidase subunit
AYR55_RS01465	COG1294	oxidase, subunit
AYR55_RS01470	COG4988	ABC transporter
AYR55_RS01475	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AYR55_RS01485	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AYR55_RS01490	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AYR55_RS01500	COG4129	membrane
AYR55_RS01505	COG1705	Flagellar rod assembly protein muramidase FlgJ
AYR55_RS01510	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AYR55_RS01515	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AYR55_RS01520	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AYR55_RS01530	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AYR55_RS01540	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AYR55_RS01545	COG0154	amidase activity
AYR55_RS01550	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AYR55_RS01555	COG1597	lipid kinase activity
AYR55_RS01570	COG4372	Transposase
AYR55_RS01575	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AYR55_RS01585	COG2252	PERMEase
AYR55_RS01590	COG0531	amino acid
AYR55_RS01595	COG3757	hydrolase, family 25
AYR55_RS01595	COG3409	Peptidoglycan-binding domain 1 protein
AYR55_RS01605	COG0673	inositol 2-dehydrogenase activity
AYR55_RS01610	COG0513	Belongs to the DEAD box helicase family
AYR55_RS01630	COG0463	Glycosyl transferase, family 2
AYR55_RS01635	COG0716	FMN binding
AYR55_RS01645	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AYR55_RS01650	COG1012	belongs to the aldehyde dehydrogenase family
AYR55_RS01655	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AYR55_RS01660	COG2137	regulation of response to DNA damage stimulus
AYR55_RS01665	COG3557	Belongs to the UPF0374 family
AYR55_RS01675	COG0628	permease
AYR55_RS01680	COG1253	flavin adenine dinucleotide binding
AYR55_RS01700	COG0542	response to heat
AYR55_RS01720	COG0438	transferase activity, transferring glycosyl groups
AYR55_RS01725	COG0438	transferase activity, transferring glycosyl groups
AYR55_RS01735	COG4703	Protein of unknown function (DUF1797)
AYR55_RS01740	COG1368	sulfuric ester hydrolase activity
AYR55_RS01825	COG1234	tRNA 3'-trailer cleavage
AYR55_RS01830	COG1393	Belongs to the ArsC family
AYR55_RS01835	COG4862	establishment of competence for transformation
AYR55_RS01865	COG2357	RelA SpoT domain protein
AYR55_RS01870	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AYR55_RS01875	COG0564	pseudouridine synthase activity
AYR55_RS01880	COG2239	Acts as a magnesium transporter
AYR55_RS01885	COG3142	Participates in the control of copper homeostasis
AYR55_RS01890	COG2706	6-phosphogluconolactonase activity
AYR55_RS01900	COG0628	permease
AYR55_RS01905	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AYR55_RS01910	COG0516	GMP reductase activity
AYR55_RS01935	COG1396	sequence-specific DNA binding
AYR55_RS01980	COG1846	Transcriptional regulator
AYR55_RS01985	COG0305	Participates in initiation and elongation during chromosome replication
AYR55_RS02045	COG3328	transposase activity
AYR55_RS02130	COG5280	Phage tail tape measure protein TP901
AYR55_RS02130	COG3953	SLT domain
AYR55_RS02225	COG1674	ftsk spoiiie
AYR55_RS02230	COG0612	Peptidase, M16
AYR55_RS02235	COG0612	Peptidase, M16
AYR55_RS02240	COG0300	oxidoreductase activity
AYR55_RS02245	COG1426	Protein conserved in bacteria
AYR55_RS02250	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AYR55_RS02255	COG1546	Belongs to the CinA family
AYR55_RS02255	COG1058	Belongs to the CinA family
AYR55_RS02260	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AYR55_RS02265	COG1418	mRNA catabolic process
AYR55_RS02270	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AYR55_RS02275	COG1739	Uncharacterized protein family UPF0029
AYR55_RS02280	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
AYR55_RS02285	COG1040	competence protein
AYR55_RS02295	COG0653	protein targeting
AYR55_RS02310	COG0745	RESPONSE REGULATOR receiver
AYR55_RS02315	COG5002	protein histidine kinase activity
AYR55_RS02325	COG0573	inorganic phosphate transmembrane transporter activity
AYR55_RS02330	COG0581	inorganic phosphate transmembrane transporter activity
AYR55_RS02335	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AYR55_RS02340	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AYR55_RS02345	COG0704	Plays a role in the regulation of phosphate uptake
AYR55_RS02355	COG1983	PspC domain protein
AYR55_RS02375	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AYR55_RS02380	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AYR55_RS02390	COG0492	ferredoxin-NADP+ reductase activity
AYR55_RS02395	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AYR55_RS02410	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AYR55_RS02415	COG0137	argininosuccinate synthase activity
AYR55_RS02420	COG0165	Argininosuccinate lyase
AYR55_RS02430	COG1660	Displays ATPase and GTPase activities
AYR55_RS02435	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AYR55_RS02440	COG1481	regulation of sporulation
AYR55_RS02445	COG0740	serine-type endopeptidase activity
AYR55_RS02455	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AYR55_RS02470	COG0126	phosphoglycerate kinase activity
AYR55_RS02480	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AYR55_RS02485	COG0557	exoribonuclease II activity
AYR55_RS02495	COG1126	abc transporter atp-binding protein
AYR55_RS02500	COG0765	amino acid transport
AYR55_RS02515	COG0561	phosphatase activity
AYR55_RS02520	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AYR55_RS02525	COG0280	phosphate acetyltransferase
AYR55_RS02530	COG0802	atpase or kinase
AYR55_RS02535	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AYR55_RS02540	COG2176	DNA-directed DNA polymerase activity
AYR55_RS02545	COG0708	Exodeoxyribonuclease III
AYR55_RS02550	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AYR55_RS02560	COG0604	alcohol dehydrogenase
AYR55_RS02565	COG3842	ATPase activity
AYR55_RS02570	COG1176	ABC-type spermidine putrescine transport system, permease component I
AYR55_RS02575	COG1177	transmembrane transport
AYR55_RS02595	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AYR55_RS02600	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AYR55_RS02615	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AYR55_RS02620	COG1459	type II secretion system
AYR55_RS02625	COG4537	Required for transformation and DNA binding
AYR55_RS02650	COG0827	DNA restriction-modification system
AYR55_RS02655	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AYR55_RS02665	COG1113	amino acid transport
AYR55_RS02750	COG0561	phosphatase activity
AYR55_RS02755	COG0745	RESPONSE REGULATOR receiver
AYR55_RS02760	COG5002	protein histidine kinase activity
AYR55_RS02760	COG3850	Histidine kinase
AYR55_RS02775	COG4372	Transposase
AYR55_RS02790	COG1368	sulfuric ester hydrolase activity
AYR55_RS02800	COG4975	Glucose uptake
AYR55_RS02805	COG0166	Belongs to the GPI family
AYR55_RS02835	COG1428	Deoxynucleoside kinase
AYR55_RS02840	COG1278	Cold shock
AYR55_RS02875	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AYR55_RS02880	COG1482	cell wall glycoprotein biosynthetic process
AYR55_RS02885	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AYR55_RS02890	COG1435	thymidine kinase activity
AYR55_RS02895	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AYR55_RS02900	COG2890	protein-(glutamine-N5) methyltransferase activity
AYR55_RS02905	COG0009	L-threonylcarbamoyladenylate synthase
AYR55_RS02915	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AYR55_RS02925	COG0356	it plays a direct role in the translocation of protons across the membrane
AYR55_RS02935	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AYR55_RS02940	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AYR55_RS02955	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AYR55_RS02960	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AYR55_RS02970	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AYR55_RS02975	COG1077	Cell shape determining protein MreB Mrl
AYR55_RS02995	COG0772	Belongs to the SEDS family
AYR55_RS03000	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AYR55_RS03005	COG2011	ABC-type metal ion transport system permease component
AYR55_RS03010	COG1464	Belongs to the NlpA lipoprotein family
AYR55_RS03020	COG0719	Fe-S assembly protein
AYR55_RS03025	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AYR55_RS03035	COG0719	Fe-S assembly protein
AYR55_RS03050	COG4372	Transposase
AYR55_RS03060	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AYR55_RS03065	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AYR55_RS03070	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
AYR55_RS03070	COG1605	Chorismate mutase
AYR55_RS03075	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AYR55_RS03080	COG1605	Chorismate mutase
AYR55_RS03080	COG0077	Prephenate dehydratase
AYR55_RS03085	COG1881	PFAM PEBP family protein
AYR55_RS03090	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AYR55_RS03095	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AYR55_RS03100	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AYR55_RS03110	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AYR55_RS03120	COG2326	polyphosphate kinase activity
AYR55_RS03125	COG0589	response to stress
AYR55_RS03140	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AYR55_RS03145	COG1181	Belongs to the D-alanine--D-alanine ligase family
AYR55_RS03145	COG2918	glutathione biosynthetic process
AYR55_RS03155	COG4493	Belongs to the UPF0637 family
AYR55_RS03165	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AYR55_RS03170	COG1956	GAF domain-containing protein
AYR55_RS03175	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
AYR55_RS03180	COG1104	cysteine desulfurase activity
AYR55_RS03185	COG0301	tRNA thio-modification
AYR55_RS03190	COG0525	valine-tRNA ligase activity
AYR55_RS03200	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AYR55_RS03205	COG2003	Belongs to the UPF0758 family
AYR55_RS03210	COG1278	Cold shock
AYR55_RS03215	COG1077	Cell shape determining protein MreB Mrl
AYR55_RS03220	COG1792	Involved in formation and maintenance of cell shape
AYR55_RS03230	COG0850	regulation of cytokinetic process
AYR55_RS03235	COG2894	cell division
AYR55_RS03240	COG0765	amino acid transport
AYR55_RS03245	COG1126	abc transporter atp-binding protein
AYR55_RS03250	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AYR55_RS03255	COG0527	aspartate kinase activity
AYR55_RS03275	COG2001	Belongs to the MraZ family
AYR55_RS03280	COG0275	rRNA processing
AYR55_RS03290	COG0768	penicillin binding
AYR55_RS03300	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AYR55_RS03305	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AYR55_RS03310	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AYR55_RS03320	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AYR55_RS03325	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AYR55_RS03330	COG1799	cell septum assembly
AYR55_RS03340	COG2302	S4 RNA-binding domain
AYR55_RS03345	COG3599	regulation of cell shape
AYR55_RS03350	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AYR55_RS03355	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AYR55_RS03360	COG2814	Major facilitator Superfamily
AYR55_RS03365	COG3853	Toxic anion resistance protein (TelA)
AYR55_RS03375	COG0494	nUDIX hydrolase
AYR55_RS03385	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AYR55_RS03390	COG1104	cysteine desulfurase activity
AYR55_RS03400	COG0482	sulfurtransferase activity
AYR55_RS03405	COG0406	alpha-ribazole phosphatase activity
AYR55_RS03415	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AYR55_RS03420	COG1597	lipid kinase activity
AYR55_RS03440	COG0242	peptide deformylase activity
AYR55_RS03450	COG4476	Belongs to the UPF0223 family
AYR55_RS03455	COG0483	inositol monophosphate 1-phosphatase activity
AYR55_RS03460	COG1217	gtp-binding protein TYPA
AYR55_RS03465	COG4838	Belongs to the UPF0358 family
AYR55_RS03470	COG0772	Belongs to the SEDS family
AYR55_RS03475	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AYR55_RS03485	COG4471	UPF0298 protein
AYR55_RS03490	COG0742	ribosomal rna small subunit methyltransferase
AYR55_RS03495	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AYR55_RS03505	COG1555	photosystem II stabilization
AYR55_RS03505	COG1596	polysaccharide export
AYR55_RS03510	COG2131	deaminase
AYR55_RS03515	COG2333	competence protein COMEC
AYR55_RS03515	COG0658	competence protein
AYR55_RS03520	COG1466	dna polymerase III delta subunit
AYR55_RS03525	COG0268	Binds directly to 16S ribosomal RNA
AYR55_RS03530	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AYR55_RS03555	COG0544	peptidyl-prolyl cis-trans isomerase activity
AYR55_RS03560	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AYR55_RS03570	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AYR55_RS03590	COG0765	amino acid transport
AYR55_RS03595	COG1126	abc transporter atp-binding protein
AYR55_RS03600	COG0322	excinuclease ABC activity
AYR55_RS03610	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AYR55_RS03610	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AYR55_RS03610	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AYR55_RS03615	COG1105	Belongs to the carbohydrate kinase PfkB family
AYR55_RS03620	COG1349	DNA-binding transcription factor activity
AYR55_RS03625	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AYR55_RS03630	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AYR55_RS03630	COG2755	lipolytic protein G-D-S-L family
AYR55_RS03635	COG1234	tRNA 3'-trailer cleavage
AYR55_RS03640	COG0300	oxidoreductase activity
AYR55_RS03645	COG5416	Lipopolysaccharide assembly protein A domain
AYR55_RS03650	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AYR55_RS03650	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AYR55_RS03665	COG3425	synthase
AYR55_RS03680	COG0582	viral genome integration into host DNA
AYR55_RS03695	COG1396	sequence-specific DNA binding
AYR55_RS03735	COG1846	Transcriptional regulator
AYR55_RS03740	COG0305	Participates in initiation and elongation during chromosome replication
AYR55_RS03900	COG5280	Phage tail tape measure protein TP901
AYR55_RS03900	COG3953	SLT domain
AYR55_RS03960	COG3942	CHAP domain
AYR55_RS03960	COG1388	LysM domain
AYR55_RS04005	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AYR55_RS04010	COG4224	UPF0291 protein
AYR55_RS04015	COG3763	UPF0154 protein
AYR55_RS04020	COG0204	Acyl-transferase
AYR55_RS04025	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AYR55_RS04030	COG2827	Endonuclease containing a URI domain
AYR55_RS04035	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AYR55_RS04045	COG0052	Belongs to the universal ribosomal protein uS2 family
AYR55_RS04065	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AYR55_RS04070	COG4589	Belongs to the CDS family
AYR55_RS04075	COG0750	zinc metalloprotease
AYR55_RS04085	COG0442	prolyl-tRNA aminoacylation
AYR55_RS04090	COG2176	DNA-directed DNA polymerase activity
AYR55_RS04095	COG0779	Required for maturation of 30S ribosomal subunits
AYR55_RS04100	COG0195	Participates in both transcription termination and antitermination
AYR55_RS04105	COG2740	Nucleic-acid-binding protein implicated in transcription termination
AYR55_RS04120	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AYR55_RS04125	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AYR55_RS04130	COG0196	riboflavin kinase activity
AYR55_RS04135	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AYR55_RS04140	COG4372	Transposase
AYR55_RS04160	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AYR55_RS04165	COG0443	Heat shock 70 kDa protein
AYR55_RS04170	COG0484	heat shock protein binding
AYR55_RS04175	COG0481	GTPase activity
AYR55_RS04200	COG1388	LysM domain
AYR55_RS04200	COG1705	Flagellar rod assembly protein muramidase FlgJ
AYR55_RS04205	COG0564	pseudouridine synthase activity
AYR55_RS04245	COG2094	Belongs to the DNA glycosylase MPG family
AYR55_RS04255	COG2264	protein methyltransferase activity
AYR55_RS04260	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AYR55_RS04270	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AYR55_RS04275	COG1490	D-aminoacyl-tRNA deacylase activity
AYR55_RS04280	COG0546	phosphoglycolate phosphatase activity
AYR55_RS04295	COG3103	Sh3 type 3 domain protein
AYR55_RS04295	COG4991	sh3 domain protein
AYR55_RS04295	COG0860	N-Acetylmuramoyl-L-alanine amidase
AYR55_RS04300	COG0124	histidyl-tRNA synthetase
AYR55_RS04305	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AYR55_RS04310	COG4372	Transposase
AYR55_RS04330	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AYR55_RS04340	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AYR55_RS04345	COG1114	Component of the transport system for branched-chain amino acids
AYR55_RS04350	COG0778	Nitroreductase
AYR55_RS04355	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
AYR55_RS04365	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AYR55_RS04370	COG1610	YqeY-like protein
AYR55_RS04385	COG1702	phosphate starvation-inducible protein PhoH
AYR55_RS04390	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AYR55_RS04395	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AYR55_RS04405	COG1381	Involved in DNA repair and RecF pathway recombination
AYR55_RS04410	COG0752	glycyl-tRNA synthetase alpha subunit
AYR55_RS04415	COG0751	glycine-tRNA ligase activity
AYR55_RS04420	COG0358	DNA primase activity
AYR55_RS04425	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AYR55_RS04435	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AYR55_RS04445	COG0542	response to heat
AYR55_RS04455	COG0587	DNA-directed DNA polymerase activity
AYR55_RS04470	COG2707	UPF0756 membrane protein
AYR55_RS04475	COG2996	Protein conserved in bacteria
AYR55_RS04480	COG0735	belongs to the Fur family
AYR55_RS04495	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AYR55_RS04500	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AYR55_RS04505	COG1187	pseudouridine synthase activity
AYR55_RS04520	COG0514	ATP-dependent DNA helicase (RecQ)
AYR55_RS04530	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AYR55_RS04535	COG0539	negative regulation of cytoplasmic translation
AYR55_RS04550	COG0457	Tetratricopeptide repeat
AYR55_RS04560	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AYR55_RS04565	COG2814	Major facilitator Superfamily
AYR55_RS04570	COG0596	Alpha beta hydrolase
AYR55_RS04580	COG0655	NAD(P)H dehydrogenase (quinone) activity
AYR55_RS04620	COG2910	NAD(P)H-binding
AYR55_RS04670	COG1301	dicarboxylic acid transport
AYR55_RS04685	COG2188	Transcriptional regulator
AYR55_RS04690	COG1131	(ABC) transporter
AYR55_RS04700	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AYR55_RS04705	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AYR55_RS04710	COG2151	metal-sulfur cluster biosynthetic enzyme
AYR55_RS04725	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AYR55_RS04725	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
AYR55_RS04730	COG1304	FMN binding
AYR55_RS04745	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AYR55_RS04750	COG1199	ATP-dependent helicase activity
AYR55_RS04750	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AYR55_RS04765	COG0017	Asparaginyl-tRNA synthetase
AYR55_RS04775	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AYR55_RS04780	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AYR55_RS04785	COG3331	DNA recombination
AYR55_RS04790	COG4474	Belongs to the UPF0398 family
AYR55_RS04795	COG3599	regulation of cell shape
AYR55_RS04805	COG0116	Belongs to the methyltransferase superfamily
AYR55_RS04830	COG0328	RNA-DNA hybrid ribonuclease activity
AYR55_RS04840	COG1278	Cold shock
AYR55_RS04845	COG2759	Belongs to the formate--tetrahydrofolate ligase family
AYR55_RS04850	COG1573	uracil-dna glycosylase
AYR55_RS04855	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AYR55_RS04860	COG0564	pseudouridine synthase activity
AYR55_RS04865	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AYR55_RS04870	COG2233	PERMEase
AYR55_RS04875	COG0540	Belongs to the ATCase OTCase family
AYR55_RS04880	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AYR55_RS04885	COG0505	Belongs to the CarA family
AYR55_RS04890	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AYR55_RS04895	COG0284	orotidine-5'-phosphate decarboxylase activity
AYR55_RS04900	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AYR55_RS04920	COG1293	RNA-binding protein homologous to eukaryotic snRNP
AYR55_RS04925	COG1307	EDD domain protein, DegV family
AYR55_RS04935	COG0372	Belongs to the citrate synthase family
AYR55_RS04940	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AYR55_RS04950	COG1227	inorganic diphosphatase activity
AYR55_RS04955	COG0583	DNA-binding transcription factor activity
AYR55_RS04965	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AYR55_RS04980	COG0187	DNA topoisomerase II activity
AYR55_RS04995	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AYR55_RS05000	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AYR55_RS05010	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
AYR55_RS05015	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AYR55_RS05020	COG0758	DNA mediated transformation
AYR55_RS05025	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AYR55_RS05030	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AYR55_RS05035	COG0300	oxidoreductase activity
AYR55_RS05045	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AYR55_RS05045	COG0574	Belongs to the PEP-utilizing enzyme family
AYR55_RS05050	COG3409	Peptidoglycan-binding domain 1 protein
AYR55_RS05050	COG0793	Belongs to the peptidase S41A family
AYR55_RS05055	COG4479	Belongs to the UPF0346 family
AYR55_RS05060	COG4698	Protein conserved in bacteria
AYR55_RS05065	COG2755	lipolytic protein G-D-S-L family
AYR55_RS05070	COG1307	EDD domain protein, DegV family
AYR55_RS05075	COG1272	protein, Hemolysin III
AYR55_RS05085	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AYR55_RS05090	COG0488	(ABC) transporter
AYR55_RS05095	COG0617	tRNA 3'-terminal CCA addition
AYR55_RS05100	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AYR55_RS05105	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AYR55_RS05110	COG1053	succinate dehydrogenase
AYR55_RS05170	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
AYR55_RS05185	COG0778	Nitroreductase
AYR55_RS05205	COG0305	Participates in initiation and elongation during chromosome replication
AYR55_RS05210	COG3022	response to hydroperoxide
AYR55_RS05235	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AYR55_RS05240	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AYR55_RS05245	COG0110	maltose O-acetyltransferase activity
AYR55_RS05250	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AYR55_RS05260	COG4115	mRNA cleavage
AYR55_RS05290	COG1088	dTDP-glucose 4,6-dehydratase activity
AYR55_RS05305	COG0656	L-ascorbic acid biosynthetic process
AYR55_RS05310	COG0789	Transcriptional regulator
AYR55_RS05355	COG0477	Major facilitator Superfamily
AYR55_RS05370	COG1028	Short-chain dehydrogenase reductase Sdr
AYR55_RS05385	COG0019	diaminopimelate decarboxylase activity
AYR55_RS05390	COG1942	4-Oxalocrotonate Tautomerase
AYR55_RS05395	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AYR55_RS05420	COG0737	Belongs to the 5'-nucleotidase family
AYR55_RS05430	COG0335	large ribosomal subunit rRNA binding
AYR55_RS05445	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AYR55_RS05450	COG1837	Belongs to the UPF0109 family
AYR55_RS05455	COG0228	four-way junction DNA binding
AYR55_RS05465	COG1063	alcohol dehydrogenase
AYR55_RS05475	COG0110	maltose O-acetyltransferase activity
AYR55_RS05515	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AYR55_RS05520	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
AYR55_RS05540	COG4372	Transposase
AYR55_RS05545	COG0552	protein localization to endoplasmic reticulum
AYR55_RS05550	COG0561	phosphatase activity
AYR55_RS05555	COG1196	nuclear chromosome segregation
AYR55_RS05560	COG0571	ribonuclease III activity
AYR55_RS05565	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AYR55_RS05570	COG0416	fatty acid biosynthetic process
AYR55_RS05575	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AYR55_RS05580	COG1461	Dihydroxyacetone kinase
AYR55_RS05585	COG1302	Protein conserved in bacteria
AYR55_RS05595	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AYR55_RS05610	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AYR55_RS05615	COG1162	GTPase activity
AYR55_RS05620	COG2815	serine threonine protein kinase
AYR55_RS05620	COG0515	serine threonine protein kinase
AYR55_RS05630	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AYR55_RS05630	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AYR55_RS05635	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AYR55_RS05640	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AYR55_RS05645	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AYR55_RS05655	COG0194	GDP metabolic process
AYR55_RS05670	COG0497	DNA recombination
AYR55_RS05675	COG1438	arginine binding
AYR55_RS05680	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
AYR55_RS05690	COG1722	exodeoxyribonuclease VII activity
AYR55_RS05695	COG1570	exodeoxyribonuclease VII activity
AYR55_RS05700	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AYR55_RS05705	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AYR55_RS05710	COG1302	Protein conserved in bacteria
AYR55_RS05715	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AYR55_RS05720	COG0006	proline dipeptidase activity
AYR55_RS05725	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AYR55_RS05735	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AYR55_RS05780	COG1012	belongs to the aldehyde dehydrogenase family
AYR55_RS05790	COG2936	dipeptidyl-peptidase activity
AYR55_RS05810	COG4372	Transposase
AYR55_RS05815	COG0174	glutamine synthetase
AYR55_RS05820	COG0789	Transcriptional regulator
AYR55_RS05825	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
AYR55_RS05830	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AYR55_RS05835	COG0584	glycerophosphoryl diester phosphodiesterase
AYR55_RS05840	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AYR55_RS05845	COG1940	carbohydrate kinase activity
AYR55_RS05855	COG0705	Rhomboid family
AYR55_RS05855	COG0457	Tetratricopeptide repeat
AYR55_RS05860	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AYR55_RS05870	COG1376	ErfK ybiS ycfS ynhG family protein
AYR55_RS05875	COG0419	ATPase involved in DNA repair
AYR55_RS05890	COG0768	penicillin binding
AYR55_RS05895	COG4485	Bacterial membrane protein, YfhO
AYR55_RS05900	COG2197	response regulator
AYR55_RS05905	COG4585	Histidine kinase
AYR55_RS05915	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AYR55_RS05920	COG0572	uridine kinase
AYR55_RS05925	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AYR55_RS05930	COG0072	phenylalanine-tRNA ligase activity
AYR55_RS05935	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AYR55_RS05940	COG1733	regulation of RNA biosynthetic process
AYR55_RS05950	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AYR55_RS05955	COG1254	Belongs to the acylphosphatase family
AYR55_RS05960	COG0706	membrane insertase activity
AYR55_RS05965	COG5002	protein histidine kinase activity
AYR55_RS05970	COG0745	RESPONSE REGULATOR receiver
AYR55_RS05975	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AYR55_RS05995	COG1323	Belongs to the UPF0348 family
AYR55_RS06000	COG2226	methyltransferase
AYR55_RS06005	COG0799	negative regulation of ribosome biogenesis
AYR55_RS06010	COG1713	HD superfamily hydrolase involved in NAD metabolism
AYR55_RS06015	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AYR55_RS06025	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AYR55_RS06030	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
AYR55_RS06035	COG0604	alcohol dehydrogenase
AYR55_RS06045	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AYR55_RS06055	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AYR55_RS06060	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AYR55_RS06065	COG1484	DNA-dependent DNA replication
AYR55_RS06070	COG3611	Membrane attachment protein
AYR55_RS06075	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AYR55_RS06080	COG0237	dephospho-CoA kinase activity
AYR55_RS06090	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AYR55_RS06090	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AYR55_RS06095	COG0670	Belongs to the BI1 family
AYR55_RS06100	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AYR55_RS06110	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AYR55_RS06115	COG0589	response to stress
AYR55_RS06125	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AYR55_RS06130	COG0510	thiamine kinase activity
AYR55_RS06140	COG1131	(ABC) transporter
AYR55_RS06145	COG0537	adenosine 5'-monophosphoramidase activity
AYR55_RS06170	COG3481	metal-dependent phosphohydrolase, HD sub domain
AYR55_RS06175	COG4717	serine-type aminopeptidase activity
AYR55_RS06180	COG0420	3'-5' exonuclease activity
AYR55_RS06185	COG3679	Belongs to the UPF0342 family
AYR55_RS06190	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AYR55_RS06195	COG0564	pseudouridine synthase activity
AYR55_RS06200	COG1438	arginine binding
AYR55_RS06205	COG0018	arginyl-trna synthetase
AYR55_RS06230	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AYR55_RS06235	COG1187	pseudouridine synthase activity
AYR55_RS06240	COG2244	polysaccharide biosynthetic process
AYR55_RS06245	COG0495	leucyl-tRNA aminoacylation
AYR55_RS06250	COG0671	phosphoesterase, PA-phosphatase related
AYR55_RS06255	COG0477	Major facilitator Superfamily
AYR55_RS06260	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AYR55_RS06400	COG1098	S1 RNA binding domain
AYR55_RS06410	COG0492	ferredoxin-NADP+ reductase activity
AYR55_RS06415	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AYR55_RS06420	COG0586	Pfam SNARE associated Golgi protein
AYR55_RS06435	COG0647	UMP catabolic process
AYR55_RS06440	COG4470	Protein conserved in bacteria
AYR55_RS06445	COG0737	Belongs to the 5'-nucleotidase family
AYR55_RS06490	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AYR55_RS06500	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AYR55_RS06515	COG0640	Transcriptional regulator
AYR55_RS06520	COG1418	mRNA catabolic process
AYR55_RS06545	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AYR55_RS06545	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AYR55_RS06550	COG1268	BioY protein
AYR55_RS06560	COG1011	Hydrolase
AYR55_RS06565	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AYR55_RS06570	COG3328	transposase activity
AYR55_RS06575	COG1609	Transcriptional regulator
AYR55_RS06580	COG0006	proline dipeptidase activity
AYR55_RS06600	COG0668	transmembrane transport
AYR55_RS06610	COG0656	L-ascorbic acid biosynthetic process
AYR55_RS06620	COG2873	o-acetylhomoserine
AYR55_RS06625	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
AYR55_RS06630	COG1316	TRANSCRIPTIONal
AYR55_RS06650	COG1854	S-ribosylhomocysteine lyase activity
AYR55_RS06660	COG0302	gtp cyclohydrolase
AYR55_RS06665	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AYR55_RS06665	COG0302	gtp cyclohydrolase
AYR55_RS06680	COG1473	amidohydrolase
AYR55_RS06685	COG2171	N-acyltransferase activity
AYR55_RS06695	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AYR55_RS06705	COG1719	4-vinyl reductase, 4VR
AYR55_RS06710	COG0322	excinuclease ABC activity
AYR55_RS06715	COG3118	belongs to the thioredoxin family
AYR55_RS06720	COG1193	negative regulation of DNA recombination
AYR55_RS06750	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AYR55_RS06755	COG0513	Belongs to the DEAD box helicase family
AYR55_RS06760	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AYR55_RS06765	COG4109	DRTGG domain
AYR55_RS06775	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AYR55_RS06780	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AYR55_RS06785	COG1454	alcohol dehydrogenase
AYR55_RS06785	COG1012	belongs to the aldehyde dehydrogenase family
AYR55_RS06790	COG1862	Preprotein translocase
AYR55_RS06795	COG0343	queuine tRNA-ribosyltransferase activity
AYR55_RS06800	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AYR55_RS06805	COG2255	four-way junction helicase activity
AYR55_RS06810	COG0632	four-way junction helicase activity
AYR55_RS06815	COG2076	Multidrug Resistance protein
AYR55_RS06825	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AYR55_RS06830	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AYR55_RS06835	COG4550	Control of competence regulator ComK, YlbF/YmcA
AYR55_RS06840	COG1692	metallophosphoesterase
AYR55_RS06845	COG0531	amino acid
AYR55_RS06850	COG0459	protein refolding
AYR55_RS06855	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AYR55_RS06860	COG1266	CAAX protease self-immunity
AYR55_RS06865	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
AYR55_RS06870	COG0488	(ABC) transporter
AYR55_RS06875	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AYR55_RS06890	COG1214	PFAM Peptidase M22, glycoprotease
AYR55_RS06905	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AYR55_RS06940	COG1368	sulfuric ester hydrolase activity
AYR55_RS06950	COG2246	polysaccharide biosynthetic process
AYR55_RS06960	COG0791	NLP P60 protein
AYR55_RS06960	COG3883	PFAM NLP P60 protein
AYR55_RS06985	COG0463	Glycosyl transferase, family 2
AYR55_RS06990	COG0463	Glycosyl transferase, family 2
AYR55_RS07030	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AYR55_RS07040	COG0438	transferase activity, transferring glycosyl groups
AYR55_RS07045	COG2244	polysaccharide biosynthetic process
AYR55_RS07050	COG0562	UDP-galactopyranose mutase
AYR55_RS07060	COG3475	LICD family
AYR55_RS07115	COG0305	Participates in initiation and elongation during chromosome replication
AYR55_RS07125	COG1316	TRANSCRIPTIONal
AYR55_RS07145	COG0564	pseudouridine synthase activity
AYR55_RS07205	COG1774	PSP1 C-terminal conserved region
AYR55_RS07215	COG3870	Protein conserved in bacteria
AYR55_RS07220	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AYR55_RS07225	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AYR55_RS07235	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AYR55_RS07245	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AYR55_RS07260	COG1285	pathogenesis
AYR55_RS07265	COG0590	tRNA wobble adenosine to inosine editing
AYR55_RS07270	COG0656	L-ascorbic acid biosynthetic process
AYR55_RS07280	COG2813	Specifically methylates the guanine in position
AYR55_RS07285	COG1393	Belongs to the ArsC family
AYR55_RS07290	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AYR55_RS07305	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AYR55_RS07305	COG0392	lysyltransferase activity
AYR55_RS07320	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AYR55_RS07325	COG0081	regulation of translation
AYR55_RS07340	COG0250	Participates in transcription elongation, termination and antitermination
AYR55_RS07375	COG0142	geranyltranstransferase activity
AYR55_RS07385	COG3688	RNA-binding protein containing a PIN domain
AYR55_RS07390	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AYR55_RS07395	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
AYR55_RS07400	COG0215	cysteine-tRNA ligase activity
AYR55_RS07415	COG4956	integral membrane protein (PIN domain superfamily)
AYR55_RS07420	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AYR55_RS07425	COG0756	dUTP diphosphatase activity
AYR55_RS07445	COG0588	phosphoglycerate mutase activity
AYR55_RS07465	COG1316	TRANSCRIPTIONal
AYR55_RS07470	COG0825	malonyl-CoA metabolic process
AYR55_RS07480	COG0439	Biotin carboxylase
AYR55_RS07490	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AYR55_RS07495	COG1304	FMN binding
AYR55_RS07500	COG0028	Belongs to the TPP enzyme family
AYR55_RS07505	COG0531	amino acid
AYR55_RS07510	COG0114	fumarate hydratase activity
AYR55_RS07530	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AYR55_RS07540	COG4464	protein tyrosine phosphatase activity
AYR55_RS07545	COG0489	protein tyrosine kinase activity
AYR55_RS07550	COG3944	biosynthesis protein
AYR55_RS07585	COG1122	ATPase activity
AYR55_RS07590	COG1122	ATPase activity
AYR55_RS07595	COG0203	ribosomal protein L17
AYR55_RS07605	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AYR55_RS07610	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AYR55_RS07615	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AYR55_RS07620	COG0563	adenylate kinase activity
AYR55_RS07635	COG1841	ribosomal large subunit assembly
AYR55_RS07640	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AYR55_RS07650	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AYR55_RS07660	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AYR55_RS07665	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AYR55_RS07670	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AYR55_RS07680	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AYR55_RS07685	COG0255	Belongs to the universal ribosomal protein uL29 family
AYR55_RS07690	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AYR55_RS07695	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AYR55_RS07700	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AYR55_RS07710	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AYR55_RS07715	COG0089	rRNA binding
AYR55_RS07720	COG0088	Forms part of the polypeptide exit tunnel
AYR55_RS07725	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AYR55_RS07740	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AYR55_RS07750	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AYR55_RS07755	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AYR55_RS07770	COG0826	peptidase U32
AYR55_RS07775	COG0826	peptidase U32
AYR55_RS07780	COG0542	response to heat
AYR55_RS07785	COG4463	regulation of RNA biosynthetic process
AYR55_RS07870	COG1428	Deoxynucleoside kinase
AYR55_RS07880	COG0833	amino acid
AYR55_RS07890	COG3527	Alpha-acetolactate decarboxylase
AYR55_RS07895	COG0028	Belongs to the TPP enzyme family
AYR55_RS07900	COG1959	2 iron, 2 sulfur cluster binding
AYR55_RS07930	COG0514	ATP-dependent DNA helicase (RecQ)
AYR55_RS07935	COG1694	Mazg nucleotide pyrophosphohydrolase
AYR55_RS07945	COG2188	Transcriptional regulator
AYR55_RS07950	COG1131	(ABC) transporter
AYR55_RS07985	COG0308	aminopeptidase N
AYR55_RS07990	COG0604	alcohol dehydrogenase
AYR55_RS08000	COG1063	alcohol dehydrogenase
AYR55_RS08015	COG0477	Major facilitator Superfamily
AYR55_RS08020	COG0640	Transcriptional regulator
AYR55_RS08035	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
AYR55_RS08040	COG0477	Major facilitator Superfamily
AYR55_RS08050	COG0583	DNA-binding transcription factor activity
AYR55_RS08055	COG2936	dipeptidyl-peptidase activity
AYR55_RS08075	COG0745	RESPONSE REGULATOR receiver
AYR55_RS08080	COG1309	transcriptional regulator
AYR55_RS08085	COG1131	(ABC) transporter
AYR55_RS08105	COG3655	Transcriptional regulator
AYR55_RS08150	COG2226	methyltransferase
AYR55_RS08155	COG0519	Catalyzes the synthesis of GMP from XMP
AYR55_RS08155	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AYR55_RS08175	COG1307	EDD domain protein, DegV family
AYR55_RS08180	COG3973	AAA domain
AYR55_RS08185	COG0586	Pfam SNARE associated Golgi protein
AYR55_RS08190	COG0475	glutathione-regulated potassium exporter activity
AYR55_RS08190	COG0569	domain protein
AYR55_RS08210	COG2267	carboxylic ester hydrolase activity
AYR55_RS08215	COG0588	phosphoglycerate mutase activity
AYR55_RS08220	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AYR55_RS08225	COG0517	IMP dehydrogenase activity
AYR55_RS08230	COG0574	Belongs to the PEP-utilizing enzyme family
AYR55_RS08230	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AYR55_RS08235	COG4122	O-methyltransferase activity
AYR55_RS08245	COG2337	Toxic component of a toxin-antitoxin (TA) module
AYR55_RS08255	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AYR55_RS08275	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AYR55_RS08280	COG1181	Belongs to the D-alanine--D-alanine ligase family
AYR55_RS08295	COG0501	Belongs to the peptidase M48B family
AYR55_RS08300	COG1704	LemA family
AYR55_RS08305	COG2814	Major facilitator Superfamily
AYR55_RS08310	COG0254	rRNA binding
AYR55_RS08315	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AYR55_RS08320	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AYR55_RS08330	COG0504	CTP synthase activity
AYR55_RS08335	COG3343	RNA polymerase activity
AYR55_RS08345	COG1078	dGTPase activity
AYR55_RS08360	COG1970	mechanosensitive ion channel activity
AYR55_RS08370	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AYR55_RS08385	COG2814	Major facilitator Superfamily
AYR55_RS08395	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AYR55_RS08400	COG4466	Protein conserved in bacteria
AYR55_RS08415	COG0084	hydrolase, TatD family'
AYR55_RS08420	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AYR55_RS08420	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AYR55_RS08425	COG0519	Catalyzes the synthesis of GMP from XMP
AYR55_RS08430	COG1801	Protein of unknown function DUF72
AYR55_RS08445	COG1051	belongs to the nudix hydrolase family
AYR55_RS08455	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AYR55_RS08490	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AYR55_RS08515	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AYR55_RS08520	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AYR55_RS08530	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AYR55_RS08535	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AYR55_RS08540	COG0505	Belongs to the CarA family
AYR55_RS08545	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AYR55_RS08560	COG4475	Protein of unknown function (DUF436)
AYR55_RS08575	COG0702	epimerase
AYR55_RS08580	COG0697	spore germination
AYR55_RS08585	COG0531	amino acid
AYR55_RS08590	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
AYR55_RS08595	COG2188	Transcriptional regulator
AYR55_RS08620	COG1983	PspC domain protein
AYR55_RS08625	COG0028	Belongs to the TPP enzyme family
AYR55_RS08630	COG0300	oxidoreductase activity
AYR55_RS08650	COG1028	Short-chain dehydrogenase reductase Sdr
AYR55_RS08655	COG3189	MarR family transcriptional regulator
AYR55_RS08670	COG2365	Tyrosine phosphatase family
AYR55_RS08685	COG1253	flavin adenine dinucleotide binding
AYR55_RS08695	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AYR55_RS08700	COG1757	Na H antiporter
AYR55_RS08740	COG3590	peptidase
AYR55_RS08775	COG0561	phosphatase activity
AYR55_RS08790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AYR55_RS08795	COG0765	amino acid transport
AYR55_RS08800	COG0765	amino acid transport
AYR55_RS08805	COG1126	abc transporter atp-binding protein
AYR55_RS08815	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AYR55_RS08820	COG0393	Putative heavy-metal-binding
AYR55_RS08835	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AYR55_RS08845	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AYR55_RS08865	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
AYR55_RS08870	COG1461	Dihydroxyacetone kinase
AYR55_RS08875	COG2376	Dihydroxyacetone kinase
AYR55_RS08895	COG0765	amino acid transport
AYR55_RS08900	COG0765	amino acid transport
AYR55_RS08905	COG1126	abc transporter atp-binding protein
AYR55_RS08910	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AYR55_RS08920	COG1757	Na H antiporter
AYR55_RS08930	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
AYR55_RS08935	COG0446	pyridine nucleotide-disulphide oxidoreductase
AYR55_RS08955	COG0367	asparagine synthase
AYR55_RS08970	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AYR55_RS08975	COG1230	cation diffusion facilitator family transporter
AYR55_RS08980	COG1227	inorganic diphosphatase activity
AYR55_RS08985	COG0038	chloride channel
AYR55_RS09020	COG1278	Cold shock
AYR55_RS09030	COG0656	L-ascorbic acid biosynthetic process
AYR55_RS09040	COG0277	FAD linked oxidase domain protein
AYR55_RS09045	COG0167	dihydroorotate dehydrogenase activity
AYR55_RS09070	COG0436	Aminotransferase
AYR55_RS09075	COG0702	epimerase
AYR55_RS09085	COG1914	H( )-stimulated, divalent metal cation uptake system
AYR55_RS09095	COG0561	phosphatase activity
AYR55_RS09100	COG1136	(ABC) transporter
AYR55_RS09105	COG0577	efflux transmembrane transporter activity
AYR55_RS09110	COG5002	protein histidine kinase activity
AYR55_RS09110	COG3850	Histidine kinase
AYR55_RS09125	COG2217	Heavy metal translocating P-type atpase
AYR55_RS09135	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AYR55_RS09150	COG0438	transferase activity, transferring glycosyl groups
AYR55_RS09155	COG0438	transferase activity, transferring glycosyl groups
AYR55_RS09165	COG2084	Dehydrogenase
AYR55_RS09180	COG4221	oxidoreductase activity
AYR55_RS09185	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AYR55_RS09190	COG0561	phosphatase activity
AYR55_RS09195	COG1120	ATPase activity
AYR55_RS09205	COG0277	FAD linked oxidase domain protein
AYR55_RS09210	COG0488	(ABC) transporter
AYR55_RS09215	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AYR55_RS09235	COG1914	H( )-stimulated, divalent metal cation uptake system
AYR55_RS09240	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AYR55_RS09245	COG4336	lyase activity
AYR55_RS09250	COG0439	Biotin carboxylase
AYR55_RS09260	COG1984	allophanate hydrolase subunit 2
AYR55_RS09265	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AYR55_RS09275	COG2814	Major facilitator Superfamily
AYR55_RS09300	COG1827	regulation of RNA biosynthetic process
AYR55_RS09315	COG0656	L-ascorbic acid biosynthetic process
AYR55_RS09330	COG0656	L-ascorbic acid biosynthetic process
AYR55_RS09340	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AYR55_RS09355	COG1194	a g-specific adenine glycosylase
AYR55_RS09365	COG4708	membrane
AYR55_RS09380	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AYR55_RS09390	COG0012	GTP binding
AYR55_RS09395	COG4481	Protein conserved in bacteria
AYR55_RS09400	COG1475	DNA binding
AYR55_RS09405	COG1192	Involved in chromosome partitioning
AYR55_RS09425	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AYR55_RS09430	COG0604	alcohol dehydrogenase
AYR55_RS09435	COG1733	regulation of RNA biosynthetic process
AYR55_RS09440	COG0577	efflux transmembrane transporter activity
AYR55_RS09440	COG1136	(ABC) transporter
AYR55_RS09455	COG0538	isocitrate dehydrogenase activity
AYR55_RS09460	COG2365	Tyrosine phosphatase family
AYR55_RS09465	COG2918	glutathione biosynthetic process
AYR55_RS09465	COG1181	Belongs to the D-alanine--D-alanine ligase family
AYR55_RS09480	COG2252	PERMEase
AYR55_RS09490	COG0024	Methionine aminopeptidase
AYR55_RS09515	COG1668	transmembrane transport
AYR55_RS09520	COG4152	abc transporter atp-binding protein
AYR55_RS09530	COG0519	Catalyzes the synthesis of GMP from XMP
AYR55_RS09535	COG0446	pyridine nucleotide-disulphide oxidoreductase
AYR55_RS09555	COG2271	Major facilitator Superfamily
AYR55_RS09560	COG0066	3-isopropylmalate dehydratase activity
AYR55_RS09565	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AYR55_RS09570	COG0473	3-isopropylmalate dehydrogenase activity
AYR55_RS09595	COG2873	o-acetylhomoserine
AYR55_RS09600	COG1473	amidohydrolase
AYR55_RS09610	COG2011	ABC-type metal ion transport system permease component
AYR55_RS09615	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AYR55_RS09625	COG3328	transposase activity
AYR55_RS09635	COG1307	EDD domain protein, DegV family
AYR55_RS09650	COG1442	glycosyl transferase family 8
AYR55_RS09660	COG1705	Flagellar rod assembly protein muramidase FlgJ
AYR55_RS09660	COG1388	LysM domain
AYR55_RS09680	COG1737	Transcriptional regulator
AYR55_RS09690	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AYR55_RS09695	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AYR55_RS09705	COG1921	L-seryl-tRNASec selenium transferase activity
AYR55_RS09720	COG1393	Belongs to the ArsC family
AYR55_RS09725	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
AYR55_RS09730	COG0463	Glycosyl transferase, family 2
AYR55_RS09730	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AYR55_RS09745	COG2249	NAD(P)H dehydrogenase (quinone) activity
AYR55_RS09750	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AYR55_RS09760	COG1113	amino acid transport
AYR55_RS09765	COG1511	domain protein
AYR55_RS09785	COG2807	transmembrane transport
AYR55_RS09790	COG1132	(ABC) transporter
AYR55_RS09805	COG0477	Major facilitator Superfamily
AYR55_RS09810	COG2814	Major facilitator Superfamily
AYR55_RS09815	COG0583	DNA-binding transcription factor activity
AYR55_RS09820	COG0431	NADPH-dependent FMN reductase
AYR55_RS09820	COG1053	succinate dehydrogenase
AYR55_RS09820	COG3976	FMN-binding domain protein
AYR55_RS09825	COG1393	Belongs to the ArsC family
AYR55_RS09830	COG2207	Transcriptional regulator
AYR55_RS09840	COG3732	PTS system glucitol sorbitol-specific
AYR55_RS09845	COG3730	PTS system glucitol sorbitol-specific
AYR55_RS09865	COG1045	serine acetyltransferase
AYR55_RS09870	COG0626	cystathionine gamma-synthase activity
AYR55_RS09880	COG1606	tRNA processing
AYR55_RS09885	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AYR55_RS09890	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
AYR55_RS09895	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
AYR55_RS09900	COG1691	(AIR) carboxylase
AYR55_RS09905	COG3875	lactate racemase activity
AYR55_RS09910	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AYR55_RS09915	COG0310	cobalt ion transport
AYR55_RS09920	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AYR55_RS09925	COG1122	ATPase activity
AYR55_RS09950	COG2814	Major facilitator Superfamily
AYR55_RS09955	COG0765	amino acid transport
AYR55_RS09975	COG2814	Major facilitator Superfamily
AYR55_RS09980	COG1328	CTP reductase activity
AYR55_RS09980	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AYR55_RS09985	COG0602	queuosine metabolic process
AYR55_RS09995	COG4876	unkown
AYR55_RS10005	COG0789	Transcriptional regulator
AYR55_RS10010	COG1573	uracil-dna glycosylase
AYR55_RS10015	COG0477	Major facilitator Superfamily
AYR55_RS10025	COG0778	Nitroreductase
AYR55_RS10030	COG0300	oxidoreductase activity
AYR55_RS10045	COG0300	oxidoreductase activity
AYR55_RS10055	COG4989	oxidoreductase activity
AYR55_RS10085	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AYR55_RS10095	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AYR55_RS10110	COG5002	protein histidine kinase activity
AYR55_RS10115	COG0745	RESPONSE REGULATOR receiver
AYR55_RS10130	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AYR55_RS10140	COG0352	thiamine-phosphate diphosphorylase activity
AYR55_RS10145	COG0351	phosphomethylpyrimidine kinase
AYR55_RS10150	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
AYR55_RS10165	COG0305	Participates in initiation and elongation during chromosome replication
AYR55_RS10170	COG0359	binds to the 23S rRNA
AYR55_RS10185	COG0629	single-stranded DNA binding
AYR55_RS10190	COG0360	Binds together with S18 to 16S ribosomal RNA
AYR55_RS10200	COG0187	DNA topoisomerase II activity
AYR55_RS10205	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AYR55_RS10215	COG0592	DNA-directed DNA polymerase activity
AYR55_RS10220	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AYR55_RS10225	COG0594	ribonuclease P activity
AYR55_RS10230	COG0706	membrane insertase activity
AYR55_RS10240	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AYR55_RS10245	COG0445	tRNA wobble uridine modification
AYR55_RS10260	COG2814	Major facilitator Superfamily
AYR55_RS10275	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AYR55_RS10285	COG3328	transposase activity
AYR55_RS10290	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AYR55_RS10295	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AYR55_RS10310	COG1968	undecaprenyl-diphosphatase activity
AYR55_RS10325	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AYR55_RS10330	COG0004	ammonium transporteR
AYR55_RS10335	COG0346	lactoylglutathione lyase activity
AYR55_RS10340	COG4989	oxidoreductase activity
AYR55_RS10345	COG2246	polysaccharide biosynthetic process
AYR55_RS10350	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AYR55_RS10350	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AYR55_RS10375	COG0673	inositol 2-dehydrogenase activity
AYR55_RS10380	COG0477	Major facilitator Superfamily
AYR55_RS10385	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AYR55_RS10390	COG3830	Belongs to the UPF0237 family
AYR55_RS10395	COG2848	UPF0210 protein
AYR55_RS10405	COG2246	polysaccharide biosynthetic process
AYR55_RS10415	COG0463	Glycosyl transferase, family 2
AYR55_RS10425	COG0586	Pfam SNARE associated Golgi protein
AYR55_RS10430	COG0642	Histidine kinase
AYR55_RS10435	COG0745	RESPONSE REGULATOR receiver
AYR55_RS10445	COG1114	Component of the transport system for branched-chain amino acids
AYR55_RS10460	COG4372	Transposase
AYR55_RS10465	COG0561	phosphatase activity
AYR55_RS10475	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AYR55_RS10475	COG2190	(PTS) system
AYR55_RS10475	COG1263	PTS System
AYR55_RS10480	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AYR55_RS10485	COG1554	hydrolase, family 65, central catalytic
AYR55_RS10540	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AYR55_RS10550	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AYR55_RS10555	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AYR55_RS10560	COG4716	Myosin-crossreactive antigen
AYR55_RS10570	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AYR55_RS10585	COG1764	response to oxidative stress
AYR55_RS10595	COG0095	Lipoate-protein ligase
AYR55_RS10600	COG0406	alpha-ribazole phosphatase activity
AYR55_RS10610	COG1393	Belongs to the ArsC family
AYR55_RS10615	COG0667	Aldo Keto reductase
AYR55_RS10640	COG1174	glycine betaine transport
AYR55_RS10645	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AYR55_RS10650	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AYR55_RS10655	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AYR55_RS10665	COG0047	phosphoribosylformylglycinamidine synthase activity
AYR55_RS10680	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AYR55_RS10685	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AYR55_RS10690	COG0138	bifunctional purine biosynthesis protein purh
AYR55_RS10695	COG0151	Belongs to the GarS family
AYR55_RS10785	COG0517	IMP dehydrogenase activity
AYR55_RS10790	COG0328	RNA-DNA hybrid ribonuclease activity
AYR55_RS10795	COG1316	TRANSCRIPTIONal
AYR55_RS10815	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AYR55_RS10835	COG0667	Aldo Keto reductase
AYR55_RS10845	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AYR55_RS10850	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
AYR55_RS10860	COG3475	LICD family
AYR55_RS10875	COG1393	Belongs to the ArsC family
AYR55_RS10880	COG0583	DNA-binding transcription factor activity
AYR55_RS10885	COG2855	membrane
AYR55_RS10890	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AYR55_RS10900	COG2738	Putative neutral zinc metallopeptidase
AYR55_RS10910	COG3442	glutamine amidotransferase
AYR55_RS10920	COG0438	transferase activity, transferring glycosyl groups
AYR55_RS10935	COG0517	IMP dehydrogenase activity
AYR55_RS10935	COG0516	GMP reductase activity
AYR55_RS10960	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AYR55_RS10965	COG0287	Prephenate dehydrogenase
AYR55_RS10970	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AYR55_RS10975	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AYR55_RS10985	COG2409	Drug exporters of the RND superfamily
AYR55_RS10985	COG1033	growth of symbiont in host cell
AYR55_RS10995	COG2814	Major facilitator Superfamily
AYR55_RS11000	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AYR55_RS11005	COG1121	(ABC) transporter
AYR55_RS11025	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AYR55_RS11055	COG2076	Multidrug Resistance protein
AYR55_RS11060	COG2076	Multidrug Resistance protein
AYR55_RS11085	COG1846	Transcriptional regulator
AYR55_RS11090	COG1929	Belongs to the glycerate kinase type-1 family
AYR55_RS11110	COG1263	PTS System
AYR55_RS11110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AYR55_RS11110	COG2190	(PTS) system
AYR55_RS11115	COG3711	transcriptional antiterminator
AYR55_RS11120	COG1263	PTS System
AYR55_RS11120	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AYR55_RS11120	COG2190	(PTS) system
AYR55_RS11125	COG2723	6-phospho-beta-galactosidase activity
AYR55_RS11145	COG0561	phosphatase activity
AYR55_RS11155	COG0730	response to heat
AYR55_RS11170	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
AYR55_RS11180	COG0561	phosphatase activity
AYR55_RS11185	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AYR55_RS11190	COG1181	Belongs to the D-alanine--D-alanine ligase family
AYR55_RS11195	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AYR55_RS11200	COG0583	DNA-binding transcription factor activity
AYR55_RS11210	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AYR55_RS11225	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AYR55_RS11230	COG0131	Imidazoleglycerol-phosphate dehydratase
AYR55_RS11240	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AYR55_RS11245	COG0107	imidazoleglycerol-phosphate synthase activity
AYR55_RS11250	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AYR55_RS11255	COG0140	phosphoribosyl-ATP diphosphatase activity
AYR55_RS11260	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AYR55_RS11270	COG1733	regulation of RNA biosynthetic process
AYR55_RS11275	COG1446	asparaginase
AYR55_RS11300	COG2814	Major facilitator Superfamily
AYR55_RS11330	COG0861	Integral membrane protein TerC family
AYR55_RS11345	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AYR55_RS11365	COG2261	transglycosylase associated protein
AYR55_RS11380	COG1302	Protein conserved in bacteria
AYR55_RS11400	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AYR55_RS11405	COG0386	Belongs to the glutathione peroxidase family
AYR55_RS11445	COG0673	inositol 2-dehydrogenase activity
AYR55_RS11460	COG0783	Belongs to the Dps family
AYR55_RS11465	COG0300	oxidoreductase activity
AYR55_RS11515	COG2814	Major facilitator Superfamily
AYR55_RS11525	COG2151	metal-sulfur cluster biosynthetic enzyme
AYR55_RS11530	COG0129	dihydroxy-acid dehydratase activity
AYR55_RS11540	COG0028	Belongs to the TPP enzyme family
AYR55_RS11545	COG0440	acetolactate synthase activity
AYR55_RS11550	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AYR55_RS11555	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AYR55_RS11560	COG1119	ATPase activity
AYR55_RS11570	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AYR55_RS11610	COG0671	phosphoesterase, PA-phosphatase related
AYR55_RS11625	COG0488	(ABC) transporter
AYR55_RS11640	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AYR55_RS11645	COG1760	l-serine dehydratase
AYR55_RS11650	COG1760	l-serine dehydratase
AYR55_RS11660	COG3001	Fructosamine kinase
AYR55_RS11710	COG3973	AAA domain
AYR55_RS11720	COG0517	IMP dehydrogenase activity
AYR55_RS11720	COG1125	glycine betaine transport
AYR55_RS11725	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AYR55_RS11765	COG1192	Involved in chromosome partitioning
AYR55_RS11780	COG3328	transposase activity
AYR55_RS11930	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AYR55_RS11940	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AYR55_RS11965	COG1546	Belongs to the CinA family
AYR55_RS11965	COG1058	Belongs to the CinA family
AYR55_RS11970	COG0028	Belongs to the TPP enzyme family
AYR55_RS11985	COG0446	pyridine nucleotide-disulphide oxidoreductase
AYR55_RS12010	COG3189	MarR family transcriptional regulator
AYR55_RS12020	COG3328	transposase activity
AYR55_RS12115	COG0463	Glycosyl transferase, family 2
AYR55_RS12125	COG2246	polysaccharide biosynthetic process
AYR55_RS12155	COG1715	Restriction endonuclease
AYR55_RS12265	COG0302	gtp cyclohydrolase
AYR55_RS12270	COG1028	Short-chain dehydrogenase reductase Sdr
AYR55_RS12285	COG1028	Short-chain dehydrogenase reductase Sdr
AYR55_RS12290	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AYR55_RS12295	COG0511	ligase activity, forming carbon-carbon bonds
AYR55_RS12300	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AYR55_RS12310	COG0439	Biotin carboxylase
AYR55_RS12315	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AYR55_RS12320	COG0825	malonyl-CoA metabolic process
AYR55_RS12325	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AYR55_RS12335	COG2801	Transposase and inactivated derivatives
AYR55_RS12350	COG3158	transport of potassium into the cell
AYR55_RS12360	COG2801	Transposase and inactivated derivatives
AYR55_RS12370	COG1192	Involved in chromosome partitioning
AYR55_RS12410	COG0789	Transcriptional regulator
AYR55_RS12445	COG1228	amidohydrolase
AYR55_RS12450	COG2801	Transposase and inactivated derivatives
AYR55_RS12460	COG1192	Involved in chromosome partitioning
AYR55_RS12475	COG1393	Belongs to the ArsC family
AYR55_RS12490	COG1192	Involved in chromosome partitioning
AYR55_RS12500	COG1113	amino acid transport
AYR55_RS12545	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AYR55_RS12555	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AYR55_RS12620	COG0582	viral genome integration into host DNA
AYR55_RS12645	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AYR55_RS12695	COG2801	Transposase and inactivated derivatives
AYR55_RS12705	COG0366	Alpha amylase catalytic
AYR55_RS12705	COG5263	repeat protein
AYR55_RS12730	COG0589	response to stress
AYR55_RS12745	COG2801	Transposase and inactivated derivatives
AYR55_RS12750	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AYR55_RS12755	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AYR55_RS12760	COG0148	phosphopyruvate hydratase activity
AYR55_RS12805	COG0463	Glycosyl transferase, family 2
AYR55_RS12885	COG2189	Belongs to the N(4) N(6)-methyltransferase family
AYR55_RS12930	COG2217	Heavy metal translocating P-type atpase
AYR55_RS12955	COG3684	Belongs to the aldolase LacD family
AYR55_RS12970	COG2801	Transposase and inactivated derivatives
AYR55_RS12980	COG1192	Involved in chromosome partitioning
AYR55_RS13085	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AYR55_RS13090	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AYR55_RS13095	COG1674	ftsk spoiiie
AYR55_RS13110	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AYR55_RS13140	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AYR55_RS13405	COG0509	glycine decarboxylation via glycine cleavage system