locus-tag	class	description
CKQ53_RS00090	COG2200	EAL domain
CKQ53_RS00095	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CKQ53_RS00105	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CKQ53_RS00110	COG0736	holo-[acyl-carrier-protein] synthase activity
CKQ53_RS00115	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CKQ53_RS00120	COG1381	Involved in DNA repair and RecF pathway recombination
CKQ53_RS00125	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CKQ53_RS00130	COG0571	ribonuclease III activity
CKQ53_RS00145	COG3026	antisigma factor binding
CKQ53_RS00160	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CKQ53_RS00165	COG0513	Belongs to the DEAD box helicase family
CKQ53_RS00170	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
CKQ53_RS00175	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CKQ53_RS00190	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CKQ53_RS00360	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CKQ53_RS00400	COG3267	Type II secretory pathway component ExeA
CKQ53_RS00400	COG3409	Peptidoglycan-binding domain 1 protein
CKQ53_RS00415	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CKQ53_RS00430	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CKQ53_RS00435	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CKQ53_RS00440	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CKQ53_RS00445	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CKQ53_RS00450	COG0316	Belongs to the HesB IscA family
CKQ53_RS00455	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CKQ53_RS00465	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CKQ53_RS00470	COG1120	ATPase activity
CKQ53_RS00475	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CKQ53_RS00480	COG1643	Atp-dependent helicase
CKQ53_RS00485	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CKQ53_RS00505	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CKQ53_RS00510	COG0617	tRNA 3'-terminal CCA addition
CKQ53_RS00515	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CKQ53_RS00520	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CKQ53_RS00525	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CKQ53_RS00530	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CKQ53_RS00535	COG0726	polysaccharide deacetylase
CKQ53_RS00540	COG0842	Transport permease protein
CKQ53_RS00545	COG1131	(ABC) transporter
CKQ53_RS00550	COG0288	reversible hydration of carbon dioxide
CKQ53_RS00555	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CKQ53_RS00570	COG3842	ATPase activity
CKQ53_RS00585	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CKQ53_RS00590	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
CKQ53_RS00600	COG1780	Probably involved in ribonucleotide reductase function
CKQ53_RS00620	COG0577	efflux transmembrane transporter activity
CKQ53_RS00620	COG1136	(ABC) transporter
CKQ53_RS00630	COG2204	response regulator
CKQ53_RS00655	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CKQ53_RS00685	COG0318	PFAM AMP-dependent synthetase and ligase
CKQ53_RS00700	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CKQ53_RS00705	COG1960	acyl-CoA dehydrogenase activity
CKQ53_RS00725	COG1960	acyl-CoA dehydrogenase activity
CKQ53_RS00780	COG1022	Amp-dependent synthetase and ligase
CKQ53_RS00785	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CKQ53_RS00785	COG2226	methyltransferase
CKQ53_RS00785	COG3433	isochorismatase activity
CKQ53_RS00790	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CKQ53_RS00790	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CKQ53_RS00795	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CKQ53_RS00815	COG2124	cytochrome p450
CKQ53_RS00855	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CKQ53_RS00860	COG0328	RNA-DNA hybrid ribonuclease activity
CKQ53_RS00865	COG2226	methyltransferase
CKQ53_RS00870	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CKQ53_RS00875	COG0741	lytic transglycosylase activity
CKQ53_RS00875	COG1388	LysM domain
CKQ53_RS00880	COG3021	interspecies interaction between organisms
CKQ53_RS00890	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CKQ53_RS00895	COG0463	Glycosyl transferase, family 2
CKQ53_RS00915	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
CKQ53_RS00920	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
CKQ53_RS00925	COG1877	trehalose-phosphatase activity
CKQ53_RS00960	COG0542	response to heat
CKQ53_RS00980	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CKQ53_RS00985	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CKQ53_RS00990	COG0077	Prephenate dehydratase
CKQ53_RS00990	COG1605	Chorismate mutase
CKQ53_RS00995	COG1605	Chorismate mutase
CKQ53_RS00995	COG0287	Prephenate dehydrogenase
CKQ53_RS01000	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CKQ53_RS01080	COG0335	large ribosomal subunit rRNA binding
CKQ53_RS01085	COG0336	Belongs to the RNA methyltransferase TrmD family
CKQ53_RS01090	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CKQ53_RS01095	COG0228	four-way junction DNA binding
CKQ53_RS01100	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CKQ53_RS01105	COG4137	Cytochrome C assembly protein
CKQ53_RS01110	COG1854	S-ribosylhomocysteine lyase activity
CKQ53_RS01115	COG2918	glutathione biosynthetic process
CKQ53_RS01120	COG1238	metal cluster binding
CKQ53_RS01125	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CKQ53_RS01150	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CKQ53_RS01160	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CKQ53_RS01165	COG2137	regulation of response to DNA damage stimulus
CKQ53_RS01170	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CKQ53_RS01175	COG1546	Belongs to the CinA family
CKQ53_RS01220	COG5645	(Lipo)protein
CKQ53_RS01230	COG0753	catalase activity
CKQ53_RS01400	COG0582	viral genome integration into host DNA
CKQ53_RS01415	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CKQ53_RS01425	COG2885	chlorophyll binding
CKQ53_RS01430	COG2199	diguanylate cyclase activity
CKQ53_RS01440	COG1073	alpha beta
CKQ53_RS01445	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
CKQ53_RS01450	COG2195	Cleaves the N-terminal amino acid of tripeptides
CKQ53_RS01455	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CKQ53_RS01460	COG3034	peptidoglycan biosynthetic process
CKQ53_RS01465	COG0121	glutamine amidotransferase
CKQ53_RS01470	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CKQ53_RS01480	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
CKQ53_RS01485	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CKQ53_RS01490	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
CKQ53_RS01495	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
CKQ53_RS01500	COG0235	Class ii aldolase
CKQ53_RS01510	COG0436	Aminotransferase
CKQ53_RS01525	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CKQ53_RS01530	COG1126	abc transporter atp-binding protein
CKQ53_RS01535	COG0765	amino acid transport
CKQ53_RS01540	COG0765	amino acid transport
CKQ53_RS01595	COG1953	Uracil, thiamine, allantoin
CKQ53_RS01600	COG0366	Alpha amylase catalytic
CKQ53_RS01605	COG0366	Alpha amylase catalytic
CKQ53_RS01610	COG4175	Glycine betaine
CKQ53_RS01615	COG4176	ABC-type proline glycine betaine transport system permease component
CKQ53_RS01620	COG2113	Glycine betaine
CKQ53_RS01625	COG2814	Major facilitator Superfamily
CKQ53_RS01630	COG1846	Transcriptional regulator
CKQ53_RS01635	COG1566	PFAM secretion protein HlyD family protein
CKQ53_RS01640	COG2814	Major facilitator Superfamily
CKQ53_RS01645	COG1621	beta-fructofuranosidase activity
CKQ53_RS01650	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CKQ53_RS01655	COG3118	belongs to the thioredoxin family
CKQ53_RS01660	COG3148	PFAM DTW domain containing protein
CKQ53_RS01665	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CKQ53_RS01670	COG0477	Major facilitator Superfamily
CKQ53_RS01710	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CKQ53_RS01715	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CKQ53_RS01720	COG2011	ABC-type metal ion transport system permease component
CKQ53_RS01735	COG1720	tRNA m6t6A37 methyltransferase activity
CKQ53_RS01740	COG0442	prolyl-tRNA aminoacylation
CKQ53_RS01755	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CKQ53_RS01760	COG0585	pseudouridine synthase activity
CKQ53_RS01765	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CKQ53_RS01770	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CKQ53_RS01775	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CKQ53_RS01785	COG0529	Catalyzes the synthesis of activated sulfate
CKQ53_RS01790	COG2895	sulfate adenylyltransferase (ATP) activity
CKQ53_RS01800	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CKQ53_RS01800	COG1648	precorrin-2 dehydrogenase activity
CKQ53_RS01810	COG0175	sulfate reduction
CKQ53_RS01815	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CKQ53_RS01820	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CKQ53_RS01825	COG0720	synthase
CKQ53_RS01830	COG0602	queuosine metabolic process
CKQ53_RS01840	COG0148	phosphopyruvate hydratase activity
CKQ53_RS01845	COG0504	CTP synthase activity
CKQ53_RS01850	COG3956	TIGRFAM MazG family protein
CKQ53_RS01855	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CKQ53_RS01860	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CKQ53_RS01870	COG0840	transmembrane signaling receptor activity
CKQ53_RS01885	COG3530	Putative quorum-sensing-regulated virulence factor
CKQ53_RS01890	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CKQ53_RS01895	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CKQ53_RS01895	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CKQ53_RS01900	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CKQ53_RS01905	COG3025	triphosphatase activity
CKQ53_RS01910	COG4991	sh3 domain protein
CKQ53_RS01915	COG0617	tRNA 3'-terminal CCA addition
CKQ53_RS01920	COG1968	undecaprenyl-diphosphatase activity
CKQ53_RS01925	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CKQ53_RS01930	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CKQ53_RS01935	COG0840	transmembrane signaling receptor activity
CKQ53_RS01940	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CKQ53_RS01945	COG2105	PFAM AIG2 family protein
CKQ53_RS01950	COG2911	Protein conserved in bacteria
CKQ53_RS01955	COG0729	surface antigen
CKQ53_RS01960	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CKQ53_RS01965	COG1253	flavin adenine dinucleotide binding
CKQ53_RS01975	COG1218	3'(2'),5'-bisphosphate nucleotidase
CKQ53_RS01985	COG0444	Belongs to the ABC transporter superfamily
CKQ53_RS01990	COG4608	Belongs to the ABC transporter superfamily
CKQ53_RS01995	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CKQ53_RS02000	COG0601	transmembrane transport
CKQ53_RS02005	COG0747	negative chemotaxis
CKQ53_RS02015	COG0545	Peptidyl-prolyl cis-trans isomerase
CKQ53_RS02020	COG3061	Opacity-associated protein A
CKQ53_RS02025	COG0359	binds to the 23S rRNA
CKQ53_RS02030	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CKQ53_RS02040	COG0360	Binds together with S18 to 16S ribosomal RNA
CKQ53_RS02050	COG1073	alpha beta
CKQ53_RS02055	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CKQ53_RS02060	COG1690	Belongs to the RtcB family
CKQ53_RS02065	COG3650	response to hydrogen peroxide
CKQ53_RS02075	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CKQ53_RS02080	COG0557	exoribonuclease II activity
CKQ53_RS02085	COG1959	2 iron, 2 sulfur cluster binding
CKQ53_RS02090	COG0840	transmembrane signaling receptor activity
CKQ53_RS02105	COG0402	S-adenosylhomocysteine deaminase activity
CKQ53_RS02115	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CKQ53_RS02120	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CKQ53_RS02125	COG0762	integral membrane protein
CKQ53_RS02130	COG1872	DUF167
CKQ53_RS02140	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CKQ53_RS02145	COG5510	response to toxic substance
CKQ53_RS02150	COG2153	protein acetylation
CKQ53_RS02155	COG0477	Major facilitator Superfamily
CKQ53_RS02160	COG0318	PFAM AMP-dependent synthetase and ligase
CKQ53_RS02160	COG0204	Acyl-transferase
CKQ53_RS02165	COG1609	Transcriptional regulator
CKQ53_RS02170	COG3835	regulator
CKQ53_RS02180	COG2610	gluconate transmembrane transporter activity
CKQ53_RS02190	COG0583	DNA-binding transcription factor activity
CKQ53_RS02220	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CKQ53_RS02235	COG1522	sequence-specific DNA binding
CKQ53_RS02245	COG1448	Aminotransferase
CKQ53_RS02250	COG0840	transmembrane signaling receptor activity
CKQ53_RS02260	COG0432	Pfam Uncharacterised protein family UPF0047
CKQ53_RS02265	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CKQ53_RS02270	COG0629	single-stranded DNA binding
CKQ53_RS02280	COG5297	Belongs to the glycosyl hydrolase family 6
CKQ53_RS02285	COG0246	Mannitol dehydrogenase
CKQ53_RS02295	COG1121	(ABC) transporter
CKQ53_RS02300	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CKQ53_RS02305	COG0803	Belongs to the bacterial solute-binding protein 9 family
CKQ53_RS02310	COG3112	Uncharacterised protein family (UPF0231)
CKQ53_RS02325	COG4771	TonB-dependent receptor
CKQ53_RS02335	COG2079	MmgE PrpD family protein
CKQ53_RS02340	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CKQ53_RS02345	COG0508	dehydrogenase complex catalyzes the overall conversion of
CKQ53_RS02350	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CKQ53_RS02360	COG1113	amino acid transport
CKQ53_RS02370	COG3725	Membrane protein required for beta-lactamase induction
CKQ53_RS02375	COG3023	N-Acetylmuramoyl-L-alanine amidase
CKQ53_RS02380	COG4969	Belongs to the N-Me-Phe pilin family
CKQ53_RS02385	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CKQ53_RS02390	COG1459	type II secretion system
CKQ53_RS02400	COG0237	dephospho-CoA kinase activity
CKQ53_RS02405	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
CKQ53_RS02410	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CKQ53_RS02415	COG0494	nUDIX hydrolase
CKQ53_RS02420	COG0653	protein targeting
CKQ53_RS02440	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CKQ53_RS02445	COG0849	cell division
CKQ53_RS02450	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CKQ53_RS02455	COG1181	Belongs to the D-alanine--D-alanine ligase family
CKQ53_RS02460	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CKQ53_RS02465	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CKQ53_RS02470	COG0772	Belongs to the SEDS family
CKQ53_RS02475	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CKQ53_RS02480	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CKQ53_RS02485	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CKQ53_RS02490	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CKQ53_RS02495	COG0768	penicillin binding
CKQ53_RS02500	COG3116	cell division
CKQ53_RS02505	COG0275	rRNA processing
CKQ53_RS02510	COG2001	Belongs to the MraZ family
CKQ53_RS02520	COG1609	Transcriptional regulator
CKQ53_RS02530	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CKQ53_RS02535	COG0473	3-isopropylmalate dehydrogenase activity
CKQ53_RS02540	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CKQ53_RS02545	COG0066	3-isopropylmalate dehydratase activity
CKQ53_RS02560	COG0477	Major facilitator Superfamily
CKQ53_RS02570	COG4533	DNA binding
CKQ53_RS02580	COG1178	ABC-type Fe3 transport system permease component
CKQ53_RS02585	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
CKQ53_RS02595	COG0028	Belongs to the TPP enzyme family
CKQ53_RS02600	COG0440	acetolactate synthase activity
CKQ53_RS02605	COG0586	Pfam SNARE associated Golgi protein
CKQ53_RS02635	COG0417	DNA replication proofreading
CKQ53_RS02645	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CKQ53_RS02650	COG0564	pseudouridine synthase activity
CKQ53_RS02655	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CKQ53_RS02660	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CKQ53_RS02665	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CKQ53_RS02670	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CKQ53_RS02675	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CKQ53_RS02680	COG2967	ApaG domain
CKQ53_RS02685	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CKQ53_RS02695	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CKQ53_RS02705	COG2966	Psort location CytoplasmicMembrane, score
CKQ53_RS02710	COG1028	Short-chain dehydrogenase reductase Sdr
CKQ53_RS02715	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CKQ53_RS02725	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CKQ53_RS02730	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CKQ53_RS02735	COG1047	Peptidyl-prolyl cis-trans
CKQ53_RS02740	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CKQ53_RS02745	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CKQ53_RS02750	COG0196	riboflavin kinase activity
CKQ53_RS02760	COG0268	Binds directly to 16S ribosomal RNA
CKQ53_RS02765	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CKQ53_RS02775	COG0484	heat shock protein binding
CKQ53_RS02780	COG0443	Heat shock 70 kDa protein
CKQ53_RS02790	COG0521	Mo-molybdopterin cofactor biosynthetic process
CKQ53_RS02795	COG3706	GGDEF domain
CKQ53_RS02805	COG3022	response to hydroperoxide
CKQ53_RS02820	COG1609	Transcriptional regulator
CKQ53_RS02830	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CKQ53_RS02840	COG0083	homoserine kinase activity
CKQ53_RS02855	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CKQ53_RS02860	COG0745	RESPONSE REGULATOR receiver
CKQ53_RS02865	COG3045	CreA protein
CKQ53_RS02870	COG2207	Transcriptional regulator
CKQ53_RS02870	COG3708	Transcriptional regulator
CKQ53_RS02880	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
CKQ53_RS02885	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
CKQ53_RS02890	COG0741	lytic transglycosylase activity
CKQ53_RS02895	COG0488	(ABC) transporter
CKQ53_RS02900	COG0583	DNA-binding transcription factor activity
CKQ53_RS02905	COG0604	alcohol dehydrogenase
CKQ53_RS02910	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CKQ53_RS02915	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CKQ53_RS02920	COG0583	DNA-binding transcription factor activity
CKQ53_RS02935	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CKQ53_RS02940	COG0668	transmembrane transport
CKQ53_RS02950	COG0126	phosphoglycerate kinase activity
CKQ53_RS02955	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CKQ53_RS02960	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CKQ53_RS02965	COG0501	Belongs to the peptidase M48B family
CKQ53_RS02970	COG1166	arginine decarboxylase activity
CKQ53_RS02980	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CKQ53_RS02985	COG2814	Major facilitator Superfamily
CKQ53_RS02990	COG3091	SprT-like family
CKQ53_RS03000	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CKQ53_RS03005	COG0189	ligase activity
CKQ53_RS03010	COG1678	Uncharacterized ACR, COG1678
CKQ53_RS03015	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CKQ53_RS03025	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CKQ53_RS03030	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CKQ53_RS03035	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
CKQ53_RS03040	COG0330	HflC and HflK could
CKQ53_RS03045	COG0330	HflC and HflK could
CKQ53_RS03055	COG1923	regulation of RNA biosynthetic process
CKQ53_RS03060	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CKQ53_RS03065	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CKQ53_RS03070	COG0860	N-Acetylmuramoyl-L-alanine amidase
CKQ53_RS03075	COG0802	atpase or kinase
CKQ53_RS03080	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CKQ53_RS03080	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CKQ53_RS03110	COG2271	Major facilitator Superfamily
CKQ53_RS03120	COG0583	DNA-binding transcription factor activity
CKQ53_RS03135	COG3209	COG3209 Rhs family protein
CKQ53_RS03150	COG3209	COG3209 Rhs family protein
CKQ53_RS03175	COG3501	Rhs element vgr protein
CKQ53_RS03185	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CKQ53_RS03195	COG0366	Alpha amylase catalytic
CKQ53_RS03260	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CKQ53_RS03265	COG1162	GTPase activity
CKQ53_RS03270	COG0688	phosphatidylethanolamine metabolic process
CKQ53_RS03275	COG3264	Mechanosensitive ion channel
CKQ53_RS03275	COG1511	domain protein
CKQ53_RS03280	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
CKQ53_RS03285	COG1053	succinate dehydrogenase
CKQ53_RS03290	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CKQ53_RS03295	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
CKQ53_RS03300	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
CKQ53_RS03310	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CKQ53_RS03315	COG1509	lysine 2,3-aminomutase activity
CKQ53_RS03325	COG0166	Belongs to the GPI family
CKQ53_RS03330	COG0527	aspartate kinase activity
CKQ53_RS03335	COG0471	metal ion transport
CKQ53_RS03340	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
CKQ53_RS03370	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CKQ53_RS03380	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CKQ53_RS03385	COG0009	L-threonylcarbamoyladenylate synthase
CKQ53_RS03390	COG0551	DNA topoisomerase type I activity
CKQ53_RS03395	COG2922	Belongs to the Smg family
CKQ53_RS03400	COG0758	DNA mediated transformation
CKQ53_RS03405	COG0242	peptide deformylase activity
CKQ53_RS03410	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CKQ53_RS03415	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CKQ53_RS03415	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CKQ53_RS03425	COG1970	mechanosensitive ion channel activity
CKQ53_RS03430	COG3036	rescue of stalled ribosome
CKQ53_RS03440	COG0203	ribosomal protein L17
CKQ53_RS03450	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CKQ53_RS03460	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CKQ53_RS03465	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CKQ53_RS03470	COG0201	protein transport
CKQ53_RS03475	COG0200	Binds to the 23S rRNA
CKQ53_RS03480	COG1841	ribosomal large subunit assembly
CKQ53_RS03485	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CKQ53_RS03490	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CKQ53_RS03495	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CKQ53_RS03500	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CKQ53_RS03505	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CKQ53_RS03510	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CKQ53_RS03515	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CKQ53_RS03535	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CKQ53_RS03540	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CKQ53_RS03550	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CKQ53_RS03565	COG0088	Forms part of the polypeptide exit tunnel
CKQ53_RS03570	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CKQ53_RS03575	COG0051	transcription antitermination factor activity, RNA binding
CKQ53_RS03590	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CKQ53_RS03600	COG0049	tRNA binding
CKQ53_RS03605	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CKQ53_RS03615	COG2923	Belongs to the DsrF TusC family
CKQ53_RS03620	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CKQ53_RS03625	COG2964	Protein conserved in bacteria
CKQ53_RS03630	COG0545	Peptidyl-prolyl cis-trans isomerase
CKQ53_RS03635	COG2900	Belongs to the SlyX family
CKQ53_RS03655	COG1047	Peptidyl-prolyl cis-trans
CKQ53_RS03665	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CKQ53_RS03665	COG0475	glutathione-regulated potassium exporter activity
CKQ53_RS03670	COG2249	NAD(P)H dehydrogenase (quinone) activity
CKQ53_RS03675	COG0488	(ABC) transporter
CKQ53_RS03685	COG0429	hydrolase of the alpha beta-hydrolase fold
CKQ53_RS03695	COG3954	Phosphoribulokinase
CKQ53_RS03700	COG1765	OsmC-like protein
CKQ53_RS03720	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CKQ53_RS03730	COG0546	phosphoglycolate phosphatase activity
CKQ53_RS03735	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CKQ53_RS03745	COG3266	domain, Protein
CKQ53_RS03745	COG3266	domain, Protein
CKQ53_RS03750	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CKQ53_RS03755	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CKQ53_RS03760	COG4796	Type ii and iii secretion system protein
CKQ53_RS03785	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CKQ53_RS03790	COG0494	nUDIX hydrolase
CKQ53_RS03800	COG1011	Hydrolase
CKQ53_RS03805	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CKQ53_RS03810	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CKQ53_RS03815	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CKQ53_RS03830	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CKQ53_RS03840	COG0028	Belongs to the TPP enzyme family
CKQ53_RS03850	COG2183	response to ionizing radiation
CKQ53_RS03870	COG1785	Belongs to the alkaline phosphatase family
CKQ53_RS03875	COG2267	carboxylic ester hydrolase activity
CKQ53_RS03880	COG1040	competence protein
CKQ53_RS03885	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CKQ53_RS03885	COG0316	Belongs to the HesB IscA family
CKQ53_RS03895	COG1349	DNA-binding transcription factor activity
CKQ53_RS03900	COG0705	Rhomboid family
CKQ53_RS03905	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CKQ53_RS03910	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CKQ53_RS03915	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CKQ53_RS03920	COG2095	MarC family integral membrane protein
CKQ53_RS03925	COG2610	gluconate transmembrane transporter activity
CKQ53_RS03930	COG1609	Transcriptional regulator
CKQ53_RS03935	COG1741	Belongs to the pirin family
CKQ53_RS03945	COG0561	phosphatase activity
CKQ53_RS03950	COG2267	carboxylic ester hydrolase activity
CKQ53_RS03955	COG1280	lysine exporter protein (LysE YggA)
CKQ53_RS03960	COG1280	lysine exporter protein (LysE YggA)
CKQ53_RS03980	COG0598	Magnesium transport protein CorA
CKQ53_RS03985	COG0210	DNA helicase
CKQ53_RS03990	COG1011	Hydrolase
CKQ53_RS04005	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CKQ53_RS04020	COG0181	hydroxymethylbilane synthase activity
CKQ53_RS04025	COG1587	Uroporphyrinogen-III synthase
CKQ53_RS04030	COG2959	enzyme of heme biosynthesis
CKQ53_RS04035	COG3071	HemY protein
CKQ53_RS04055	COG4104	PAAR repeat-containing protein
CKQ53_RS04055	COG3209	COG3209 Rhs family protein
CKQ53_RS04105	COG3501	Rhs element vgr protein
CKQ53_RS04115	COG1473	amidohydrolase
CKQ53_RS04120	COG1126	abc transporter atp-binding protein
CKQ53_RS04125	COG0765	amino acid transport
CKQ53_RS04130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CKQ53_RS04135	COG0456	acetyltransferase
CKQ53_RS04195	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
CKQ53_RS04205	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CKQ53_RS04210	COG2244	polysaccharide biosynthetic process
CKQ53_RS04215	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CKQ53_RS04220	COG0456	acetyltransferase
CKQ53_RS04225	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CKQ53_RS04230	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CKQ53_RS04240	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CKQ53_RS04245	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CKQ53_RS04250	COG3118	belongs to the thioredoxin family
CKQ53_RS04260	COG0248	Ppx GppA phosphatase
CKQ53_RS04270	COG0210	DNA helicase
CKQ53_RS04275	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CKQ53_RS04280	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CKQ53_RS04285	COG0583	DNA-binding transcription factor activity
CKQ53_RS04300	COG0129	dihydroxy-acid dehydratase activity
CKQ53_RS04310	COG3978	acetolactate synthase activity
CKQ53_RS04325	COG0606	chelatase, subunit chli
CKQ53_RS04335	COG0583	DNA-binding transcription factor activity
CKQ53_RS04375	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CKQ53_RS04380	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CKQ53_RS04405	COG0460	homoserine dehydrogenase
CKQ53_RS04405	COG0527	aspartate kinase activity
CKQ53_RS04410	COG0626	cystathionine gamma-synthase activity
CKQ53_RS04415	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
CKQ53_RS04420	COG0254	rRNA binding
CKQ53_RS04425	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CKQ53_RS04430	COG1609	Transcriptional regulator
CKQ53_RS04435	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CKQ53_RS04440	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CKQ53_RS04445	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CKQ53_RS04450	COG1575	Belongs to the MenA family. Type 1 subfamily
CKQ53_RS04455	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CKQ53_RS04460	COG3074	FtsZ-dependent cytokinesis
CKQ53_RS04465	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CKQ53_RS04475	COG1494	fructose-1,6-bisphosphatase
CKQ53_RS04485	COG3152	Membrane
CKQ53_RS04495	COG0149	triose-phosphate isomerase activity
CKQ53_RS04500	COG2957	Belongs to the agmatine deiminase family
CKQ53_RS04505	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CKQ53_RS04510	COG0205	6-phosphofructokinase activity
CKQ53_RS04515	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CKQ53_RS04555	COG3678	ATP-independent chaperone mediated protein folding
CKQ53_RS04560	COG0745	RESPONSE REGULATOR receiver
CKQ53_RS04565	COG2205	protein histidine kinase activity
CKQ53_RS04580	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CKQ53_RS04590	COG0679	Auxin Efflux Carrier
CKQ53_RS04595	COG0584	glycerophosphoryl diester phosphodiesterase
CKQ53_RS04600	COG3842	ATPase activity
CKQ53_RS04605	COG0395	ABC-type sugar transport system, permease component
CKQ53_RS04610	COG1175	transmembrane transport
CKQ53_RS04615	COG1653	transport
CKQ53_RS04620	COG0840	transmembrane signaling receptor activity
CKQ53_RS04625	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CKQ53_RS04635	COG0411	ABC transporter
CKQ53_RS04640	COG4177	L-phenylalanine transmembrane transporter activity
CKQ53_RS04645	COG0559	Belongs to the binding-protein-dependent transport system permease family
CKQ53_RS04650	COG0683	leucine binding
CKQ53_RS04655	COG0456	acetyltransferase
CKQ53_RS04665	COG2177	Part of the ABC transporter FtsEX involved in
CKQ53_RS04670	COG2884	Cell division ATP-binding protein ftsE
CKQ53_RS04675	COG0552	protein localization to endoplasmic reticulum
CKQ53_RS04680	COG0742	ribosomal rna small subunit methyltransferase
CKQ53_RS04685	COG3776	membrane
CKQ53_RS04695	COG3714	YhhN family
CKQ53_RS04705	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CKQ53_RS04715	COG1295	ribonuclease BN
CKQ53_RS04720	COG1942	4-Oxalocrotonate Tautomerase
CKQ53_RS04730	COG1301	dicarboxylic acid transport
CKQ53_RS04735	COG2200	EAL domain
CKQ53_RS04735	COG2199	diguanylate cyclase activity
CKQ53_RS04740	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CKQ53_RS04750	COG0457	Tetratricopeptide repeat
CKQ53_RS04765	COG2894	cell division
CKQ53_RS04775	COG4608	Belongs to the ABC transporter superfamily
CKQ53_RS04780	COG0444	Belongs to the ABC transporter superfamily
CKQ53_RS04785	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CKQ53_RS04790	COG0601	transmembrane transport
CKQ53_RS04795	COG0747	negative chemotaxis
CKQ53_RS04800	COG3493	citrate carrier protein
CKQ53_RS04815	COG4565	transcriptional regulatory protein
CKQ53_RS04820	COG3290	protein histidine kinase activity
CKQ53_RS04825	COG0471	metal ion transport
CKQ53_RS04830	COG0071	Belongs to the small heat shock protein (HSP20) family
CKQ53_RS04835	COG0071	Belongs to the small heat shock protein (HSP20) family
CKQ53_RS04840	COG5645	(Lipo)protein
CKQ53_RS04845	COG0823	Involved in the tonB-independent uptake of proteins
CKQ53_RS04855	COG0561	phosphatase activity
CKQ53_RS04860	COG0589	response to stress
CKQ53_RS04870	COG0306	phosphate transporter
CKQ53_RS04875	COG2081	HI0933 family
CKQ53_RS04890	COG2194	sulfuric ester hydrolase activity
CKQ53_RS04895	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CKQ53_RS04905	COG0194	GDP metabolic process
CKQ53_RS04910	COG1758	RNA polymerase activity
CKQ53_RS04915	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CKQ53_RS04920	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CKQ53_RS04925	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CKQ53_RS04930	COG2233	PERMEase
CKQ53_RS04935	COG2982	Protein involved in outer membrane biogenesis
CKQ53_RS04940	COG0456	acetyltransferase
CKQ53_RS04945	COG1490	D-aminoacyl-tRNA deacylase activity
CKQ53_RS04950	COG1011	Hydrolase
CKQ53_RS04960	COG0174	glutamine synthetase
CKQ53_RS04965	COG3852	Histidine kinase
CKQ53_RS04975	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CKQ53_RS04985	COG3078	GTPase activator activity
CKQ53_RS04995	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CKQ53_RS04995	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CKQ53_RS05010	COG3084	Protein conserved in bacteria
CKQ53_RS05015	COG0746	molybdenum cofactor guanylyltransferase activity
CKQ53_RS05020	COG1763	Mo-molybdopterin cofactor biosynthetic process
CKQ53_RS05050	COG1609	Transcriptional regulator
CKQ53_RS05055	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CKQ53_RS05060	COG1879	ABC-type sugar transport system periplasmic component
CKQ53_RS05065	COG1172	Belongs to the binding-protein-dependent transport system permease family
CKQ53_RS05070	COG1129	ABC transporter
CKQ53_RS05075	COG1869	D-ribose catabolic process
CKQ53_RS05080	COG3111	PFAM Bacterial OB fold (BOF) protein
CKQ53_RS05085	COG0745	RESPONSE REGULATOR receiver
CKQ53_RS05090	COG0642	Histidine kinase
CKQ53_RS05095	COG3158	transport of potassium into the cell
CKQ53_RS05100	COG0714	Associated with various cellular activities
CKQ53_RS05105	COG2425	protein containing a von Willebrand factor type A (vWA) domain
CKQ53_RS05110	COG1522	sequence-specific DNA binding
CKQ53_RS05115	COG0716	FMN binding
CKQ53_RS05120	COG0445	tRNA wobble uridine modification
CKQ53_RS05125	COG0357	Ribosomal RNA small subunit methyltransferase G
CKQ53_RS05130	COG3312	ion transport
CKQ53_RS05135	COG0356	it plays a direct role in the translocation of protons across the membrane
CKQ53_RS05145	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CKQ53_RS05150	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CKQ53_RS05155	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CKQ53_RS05160	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CKQ53_RS05165	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CKQ53_RS05170	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CKQ53_RS05175	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CKQ53_RS05180	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CKQ53_RS05185	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CKQ53_RS05190	COG0573	inorganic phosphate transmembrane transporter activity
CKQ53_RS05195	COG0581	inorganic phosphate transmembrane transporter activity
CKQ53_RS05200	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CKQ53_RS05210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CKQ53_RS05220	COG0765	amino acid transport
CKQ53_RS05225	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CKQ53_RS05230	COG2252	PERMEase
CKQ53_RS05235	COG2091	lysine biosynthetic process via aminoadipic acid
CKQ53_RS05240	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CKQ53_RS05245	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CKQ53_RS05245	COG0493	'glutamate synthase
CKQ53_RS05250	COG1289	transmembrane transporter activity
CKQ53_RS05255	COG0697	spore germination
CKQ53_RS05270	COG1984	allophanate hydrolase subunit 2
CKQ53_RS05275	COG0436	Aminotransferase
CKQ53_RS05290	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CKQ53_RS05295	COG4221	oxidoreductase activity
CKQ53_RS05300	COG0765	amino acid transport
CKQ53_RS05305	COG0765	amino acid transport
CKQ53_RS05315	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CKQ53_RS05335	COG1304	FMN binding
CKQ53_RS05345	COG1657	PFAM Prenyltransferase squalene oxidase
CKQ53_RS05350	COG0142	geranyltranstransferase activity
CKQ53_RS05355	COG2124	cytochrome p450
CKQ53_RS05360	COG1028	Short-chain dehydrogenase reductase Sdr
CKQ53_RS05365	COG2124	cytochrome p450
CKQ53_RS05370	COG2124	cytochrome p450
CKQ53_RS05380	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CKQ53_RS05385	COG0706	membrane insertase activity
CKQ53_RS05400	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CKQ53_RS05410	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CKQ53_RS05415	COG0592	DNA-directed DNA polymerase activity
CKQ53_RS05420	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CKQ53_RS05435	COG0742	ribosomal rna small subunit methyltransferase
CKQ53_RS05440	COG0339	signal peptide processing
CKQ53_RS05455	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CKQ53_RS05460	COG1234	tRNA 3'-trailer cleavage
CKQ53_RS05465	COG4650	regulator
CKQ53_RS05475	COG3541	Predicted nucleotidyltransferase
CKQ53_RS05480	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CKQ53_RS05500	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CKQ53_RS05505	COG1609	Transcriptional regulator
CKQ53_RS05515	COG0837	glucose binding
CKQ53_RS05520	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CKQ53_RS05525	COG3338	carbonate dehydratase activity
CKQ53_RS05535	COG4221	oxidoreductase activity
CKQ53_RS05540	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CKQ53_RS05550	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CKQ53_RS05555	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CKQ53_RS05560	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CKQ53_RS05565	COG1309	transcriptional regulator
CKQ53_RS05570	COG0493	'glutamate synthase
CKQ53_RS05590	COG3977	Valine--pyruvate aminotransferase
CKQ53_RS05600	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CKQ53_RS05605	COG2188	Transcriptional regulator
CKQ53_RS05610	COG1397	ADP-ribosylglycohydrolase
CKQ53_RS05615	COG2211	Major facilitator Superfamily
CKQ53_RS05620	COG2818	Glycosylase
CKQ53_RS05625	COG0730	response to heat
CKQ53_RS05630	COG0752	glycyl-tRNA synthetase alpha subunit
CKQ53_RS05635	COG0751	glycine-tRNA ligase activity
CKQ53_RS05645	COG0840	transmembrane signaling receptor activity
CKQ53_RS05650	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CKQ53_RS05655	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CKQ53_RS05660	COG1012	belongs to the aldehyde dehydrogenase family
CKQ53_RS05665	COG3274	enterobacterial common antigen metabolic process
CKQ53_RS05680	COG0137	argininosuccinate synthase activity
CKQ53_RS05705	COG2200	EAL domain
CKQ53_RS05710	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
CKQ53_RS05735	COG3623	hexulose-6-phosphate isomerase
CKQ53_RS05750	COG2188	Transcriptional regulator
CKQ53_RS05755	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CKQ53_RS05760	COG2222	sugar isomerase
CKQ53_RS05765	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CKQ53_RS05800	COG1561	YicC-like family, N-terminal region
CKQ53_RS05805	COG0583	DNA-binding transcription factor activity
CKQ53_RS05825	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CKQ53_RS05830	COG0601	transmembrane transport
CKQ53_RS05835	COG0747	negative chemotaxis
CKQ53_RS05840	COG4172	Belongs to the ABC transporter superfamily
CKQ53_RS05845	COG4948	Mandelate Racemase Muconate Lactonizing
CKQ53_RS05860	COG2149	membrane
CKQ53_RS05865	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CKQ53_RS05875	COG1309	transcriptional regulator
CKQ53_RS05880	COG0756	dUTP diphosphatase activity
CKQ53_RS05885	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CKQ53_RS05890	COG2003	Belongs to the UPF0758 family
CKQ53_RS05910	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CKQ53_RS05920	COG1519	Transferase
CKQ53_RS05925	COG0438	transferase activity, transferring glycosyl groups
CKQ53_RS05935	COG0859	PFAM glycosyl transferase family 9
CKQ53_RS05945	COG0859	PFAM glycosyl transferase family 9
CKQ53_RS05960	COG0859	PFAM glycosyl transferase family 9
CKQ53_RS05965	COG0859	PFAM glycosyl transferase family 9
CKQ53_RS05970	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CKQ53_RS05975	COG2861	carbohydrate metabolic process
CKQ53_RS05980	COG4942	peptidase
CKQ53_RS05985	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CKQ53_RS05990	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CKQ53_RS05995	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CKQ53_RS06000	COG1045	serine acetyltransferase
CKQ53_RS06015	COG0583	DNA-binding transcription factor activity
CKQ53_RS06020	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CKQ53_RS06040	COG1028	Short-chain dehydrogenase reductase Sdr
CKQ53_RS06060	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CKQ53_RS06065	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CKQ53_RS06070	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CKQ53_RS06075	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CKQ53_RS06080	COG0165	Argininosuccinate lyase
CKQ53_RS06085	COG1322	Protein conserved in bacteria
CKQ53_RS06090	COG2226	methyltransferase
CKQ53_RS06095	COG3165	ubiquinone biosynthetic process from chorismate
CKQ53_RS06100	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CKQ53_RS06110	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CKQ53_RS06115	COG0805	protein transport
CKQ53_RS06120	COG0084	hydrolase, TatD family'
CKQ53_RS06135	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CKQ53_RS06145	COG0006	proline dipeptidase activity
CKQ53_RS06150	COG1739	Uncharacterized protein family UPF0029
CKQ53_RS06190	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CKQ53_RS06195	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CKQ53_RS06195	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CKQ53_RS06200	COG1072	(Pantothenic acid kinase))
CKQ53_RS06230	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CKQ53_RS06240	COG0250	Participates in transcription elongation, termination and antitermination
CKQ53_RS06250	COG0081	regulation of translation
CKQ53_RS06255	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CKQ53_RS06260	COG0222	ribosome binding
CKQ53_RS06265	COG0085	RNA polymerase activity
CKQ53_RS06270	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CKQ53_RS06280	COG5457	Domain of unknown function (DUF1127)
CKQ53_RS06285	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CKQ53_RS06295	COG2022	thiamine diphosphate biosynthetic process
CKQ53_RS06300	COG2104	thiamine diphosphate biosynthetic process
CKQ53_RS06305	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CKQ53_RS06310	COG0352	thiamine-phosphate diphosphorylase activity
CKQ53_RS06315	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CKQ53_RS06320	COG2816	NAD+ diphosphatase activity
CKQ53_RS06325	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CKQ53_RS06330	COG1515	deoxyribonuclease V activity
CKQ53_RS06355	COG0138	bifunctional purine biosynthesis protein purh
CKQ53_RS06390	COG1126	abc transporter atp-binding protein
CKQ53_RS06395	COG0765	amino acid transport
CKQ53_RS06400	COG4597	amino acid ABC transporter
CKQ53_RS06405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CKQ53_RS06410	COG0765	amino acid transport
CKQ53_RS06415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CKQ53_RS06420	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CKQ53_RS06435	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CKQ53_RS06450	COG2264	protein methyltransferase activity
CKQ53_RS06455	COG4145	pantothenate transmembrane transporter activity
CKQ53_RS06460	COG3924	membrane
CKQ53_RS06465	COG0439	Biotin carboxylase
CKQ53_RS06470	COG0511	ligase activity, forming carbon-carbon bonds
CKQ53_RS06475	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CKQ53_RS06480	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
CKQ53_RS06490	COG0604	alcohol dehydrogenase
CKQ53_RS06495	COG2199	diguanylate cyclase activity
CKQ53_RS06495	COG2200	EAL domain
CKQ53_RS06500	COG1077	Cell shape determining protein MreB Mrl
CKQ53_RS06505	COG1792	Involved in formation and maintenance of cell shape
CKQ53_RS06510	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CKQ53_RS06515	COG0424	maF-like protein
CKQ53_RS06520	COG1530	ribonuclease E activity
CKQ53_RS06525	COG3164	Protein of unknown function
CKQ53_RS06530	COG0312	modulator of DNA gyrase
CKQ53_RS06535	COG0583	DNA-binding transcription factor activity
CKQ53_RS06545	COG1566	PFAM secretion protein HlyD family protein
CKQ53_RS06550	COG1289	transmembrane transporter activity
CKQ53_RS06555	COG1280	lysine exporter protein (LysE YggA)
CKQ53_RS06560	COG3028	Belongs to the UPF0307 family
CKQ53_RS06565	COG0312	modulator of DNA gyrase
CKQ53_RS06570	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CKQ53_RS06575	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CKQ53_RS06580	COG3454	Phosphonate metabolism
CKQ53_RS06585	COG4778	phosphonate C-P lyase system protein PhnL
CKQ53_RS06590	COG4107	phosphonate C-P lyase system protein PhnK
CKQ53_RS06595	COG3627	carbon phosphorus lyase activity
CKQ53_RS06600	COG3626	phosphonate metabolism
CKQ53_RS06605	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
CKQ53_RS06610	COG3624	Phosphonate C-P lyase system protein PhnG
CKQ53_RS06630	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CKQ53_RS06635	COG1660	Displays ATPase and GTPase activities
CKQ53_RS06640	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CKQ53_RS06650	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CKQ53_RS06655	COG1137	ATPase activity
CKQ53_RS06660	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CKQ53_RS06665	COG3117	lipopolysaccharide transmembrane transporter activity
CKQ53_RS06670	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CKQ53_RS06675	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CKQ53_RS06675	COG0517	IMP dehydrogenase activity
CKQ53_RS06680	COG0530	calcium, potassium:sodium antiporter activity
CKQ53_RS06685	COG1127	ABC transporter
CKQ53_RS06690	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CKQ53_RS06695	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CKQ53_RS06700	COG2854	intermembrane phospholipid transfer
CKQ53_RS06705	COG3113	response to antibiotic
CKQ53_RS06710	COG5007	Belongs to the BolA IbaG family
CKQ53_RS06715	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CKQ53_RS06720	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CKQ53_RS06725	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CKQ53_RS06730	COG3105	Protein conserved in bacteria
CKQ53_RS06735	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CKQ53_RS06750	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CKQ53_RS06755	COG0625	glutathione transferase activity
CKQ53_RS06760	COG2969	positive regulation of protein catabolic process
CKQ53_RS06770	COG0493	'glutamate synthase
CKQ53_RS06775	COG0067	glutamate synthase
CKQ53_RS06775	COG0069	glutamate synthase activity
CKQ53_RS06775	COG0070	glutamate synthase
CKQ53_RS06780	COG1242	4 iron, 4 sulfur cluster binding
CKQ53_RS06785	COG0784	Response regulator, receiver
CKQ53_RS06785	COG2198	Histidine kinase
CKQ53_RS06785	COG5002	protein histidine kinase activity
CKQ53_RS06790	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
CKQ53_RS06795	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CKQ53_RS06800	COG2823	Periplasmic or secreted lipoprotein
CKQ53_RS06805	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CKQ53_RS06810	COG0792	nuclease activity
CKQ53_RS06815	COG3107	peptidoglycan biosynthetic process
CKQ53_RS06820	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CKQ53_RS06830	COG3384	dioxygenase
CKQ53_RS06840	COG0754	glutathionylspermidine amidase activity
CKQ53_RS06845	COG5463	Belongs to the UPF0441 family
CKQ53_RS06850	COG1538	Outer membrane efflux protein
CKQ53_RS06855	COG0494	nUDIX hydrolase
CKQ53_RS06860	COG3151	Protein conserved in bacteria
CKQ53_RS06865	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CKQ53_RS06870	COG3150	esterase
CKQ53_RS06880	COG0583	DNA-binding transcription factor activity
CKQ53_RS06885	COG2249	NAD(P)H dehydrogenase (quinone) activity
CKQ53_RS06895	COG0204	Acyl-transferase
CKQ53_RS06900	COG2132	Multicopper oxidase
CKQ53_RS06905	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CKQ53_RS06915	COG1397	ADP-ribosylglycohydrolase
CKQ53_RS06920	COG2186	Transcriptional regulator
CKQ53_RS06925	COG0656	L-ascorbic acid biosynthetic process
CKQ53_RS06930	COG1979	alcohol dehydrogenase
CKQ53_RS06935	COG0778	Nitroreductase
CKQ53_RS06940	COG2207	Transcriptional regulator
CKQ53_RS06960	COG0848	biopolymer transport protein
CKQ53_RS06990	COG3787	Belongs to the UPF0306 family
CKQ53_RS06995	COG0602	queuosine metabolic process
CKQ53_RS07000	COG1328	CTP reductase activity
CKQ53_RS07020	COG0601	transmembrane transport
CKQ53_RS07025	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CKQ53_RS07030	COG4172	Belongs to the ABC transporter superfamily
CKQ53_RS07040	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
CKQ53_RS07045	COG0540	Belongs to the ATCase OTCase family
CKQ53_RS07050	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CKQ53_RS07060	COG0456	acetyltransferase
CKQ53_RS07070	COG2927	DNA polymerase III (CHI subunit)
CKQ53_RS07075	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CKQ53_RS07085	COG0795	lipopolysaccharide-transporting ATPase activity
CKQ53_RS07090	COG0795	lipopolysaccharide-transporting ATPase activity
CKQ53_RS07095	COG2733	membrane
CKQ53_RS07265	COG3829	transcription factor binding
CKQ53_RS07305	COG2197	response regulator
CKQ53_RS07310	COG3851	Histidine kinase
CKQ53_RS07315	COG2271	Major facilitator Superfamily
CKQ53_RS07320	COG1605	Chorismate mutase
CKQ53_RS07330	COG0659	secondary active sulfate transmembrane transporter activity
CKQ53_RS07335	COG0288	reversible hydration of carbon dioxide
CKQ53_RS07345	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CKQ53_RS07350	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CKQ53_RS07355	COG0006	proline dipeptidase activity
CKQ53_RS07365	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
CKQ53_RS07375	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CKQ53_RS07390	COG0560	Phosphoserine phosphatase
CKQ53_RS07395	COG3726	membrane protein affecting hemolysin expression
CKQ53_RS07400	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CKQ53_RS07405	COG2823	Periplasmic or secreted lipoprotein
CKQ53_RS07415	COG0084	hydrolase, TatD family'
CKQ53_RS07420	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CKQ53_RS07425	COG2977	Belongs to the P-Pant transferase superfamily
CKQ53_RS07430	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
CKQ53_RS07465	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CKQ53_RS07490	COG1819	glycosyl
CKQ53_RS07495	COG0659	secondary active sulfate transmembrane transporter activity
CKQ53_RS07515	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CKQ53_RS07520	COG0679	Auxin Efflux Carrier
CKQ53_RS07540	COG0747	negative chemotaxis
CKQ53_RS07545	COG0601	transmembrane transport
CKQ53_RS07550	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CKQ53_RS07560	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CKQ53_RS07605	COG0789	Transcriptional regulator
CKQ53_RS07635	COG3423	Transcriptional regulator
CKQ53_RS07650	COG0582	viral genome integration into host DNA
CKQ53_RS07660	COG1309	transcriptional regulator
CKQ53_RS07665	COG4232	protein-disulfide reductase activity
CKQ53_RS07670	COG1324	tolerance protein
CKQ53_RS07685	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CKQ53_RS07695	COG3161	chorismate lyase activity
CKQ53_RS07700	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CKQ53_RS07705	COG2937	Belongs to the GPAT DAPAT family
CKQ53_RS07710	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CKQ53_RS07715	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CKQ53_RS07720	COG0735	belongs to the Fur family
CKQ53_RS07725	COG1741	Belongs to the pirin family
CKQ53_RS07730	COG0583	DNA-binding transcription factor activity
CKQ53_RS07735	COG0435	Glutathione S-transferase
CKQ53_RS07740	COG2259	Doxx family
CKQ53_RS07750	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
CKQ53_RS07755	COG4575	ribosome binding
CKQ53_RS07765	COG0586	Pfam SNARE associated Golgi protein
CKQ53_RS07770	COG0861	Integral membrane protein TerC family
CKQ53_RS07775	COG2813	Specifically methylates the guanine in position
CKQ53_RS07785	COG3678	ATP-independent chaperone mediated protein folding
CKQ53_RS07860	COG3663	DNA glycosylase
CKQ53_RS07865	COG1422	Protein of unknown function (DUF1090)
CKQ53_RS07875	COG0358	DNA primase activity
CKQ53_RS07880	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CKQ53_RS07890	COG1438	arginine binding
CKQ53_RS07900	COG3423	Transcriptional regulator
CKQ53_RS07915	COG0142	geranyltranstransferase activity
CKQ53_RS07920	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CKQ53_RS07930	COG0697	spore germination
CKQ53_RS07935	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CKQ53_RS07940	COG2027	D-alanyl-D-alanine carboxypeptidase
CKQ53_RS07950	COG1534	Rna-binding protein
CKQ53_RS07960	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CKQ53_RS07965	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CKQ53_RS07970	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CKQ53_RS07975	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CKQ53_RS07990	COG0779	Required for maturation of 30S ribosomal subunits
CKQ53_RS07995	COG0195	Participates in both transcription termination and antitermination
CKQ53_RS08000	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CKQ53_RS08005	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CKQ53_RS08010	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CKQ53_RS08020	COG1185	polyribonucleotide nucleotidyltransferase activity
CKQ53_RS08035	COG0513	Belongs to the DEAD box helicase family
CKQ53_RS08040	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CKQ53_RS08045	COG0826	peptidase U32
CKQ53_RS08050	COG0826	peptidase U32
CKQ53_RS08055	COG3154	lipid carrier protein
CKQ53_RS08060	COG3153	acetyltransferase
CKQ53_RS08065	COG2827	Endonuclease containing a URI domain
CKQ53_RS08070	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CKQ53_RS08075	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CKQ53_RS08080	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CKQ53_RS08085	COG0813	purine-nucleoside phosphorylase activity
CKQ53_RS08095	COG4178	(ABC) transporter
CKQ53_RS08105	COG3712	iron ion homeostasis
CKQ53_RS08110	COG1595	DNA-templated transcription, initiation
CKQ53_RS08115	COG0456	acetyltransferase
CKQ53_RS08120	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
CKQ53_RS08125	COG2813	Specifically methylates the guanine in position
CKQ53_RS08130	COG0667	Aldo Keto reductase
CKQ53_RS08135	COG0583	DNA-binding transcription factor activity
CKQ53_RS08160	COG4774	siderophore transport
CKQ53_RS08180	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CKQ53_RS08185	COG0509	glycine decarboxylation via glycine cleavage system
CKQ53_RS08190	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CKQ53_RS08190	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CKQ53_RS08225	COG1272	protein, Hemolysin III
CKQ53_RS08230	COG0354	folic acid binding
CKQ53_RS08235	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CKQ53_RS08245	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
CKQ53_RS08250	COG0716	FMN binding
CKQ53_RS08255	COG0477	Major facilitator Superfamily
CKQ53_RS08260	COG4974	Belongs to the 'phage' integrase family
CKQ53_RS08265	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CKQ53_RS08270	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CKQ53_RS08280	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CKQ53_RS08295	COG1234	tRNA 3'-trailer cleavage
CKQ53_RS08305	COG1522	sequence-specific DNA binding
CKQ53_RS08310	COG2814	Major facilitator Superfamily
CKQ53_RS08340	COG1088	dTDP-glucose 4,6-dehydratase activity
CKQ53_RS08390	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CKQ53_RS08400	COG0438	transferase activity, transferring glycosyl groups
CKQ53_RS08420	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CKQ53_RS08425	COG1653	transport
CKQ53_RS08430	COG3842	ATPase activity
CKQ53_RS08435	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CKQ53_RS08440	COG0395	ABC-type sugar transport system, permease component
CKQ53_RS08445	COG1175	transmembrane transport
CKQ53_RS08450	COG1560	Kdo2-lipid A biosynthetic process
CKQ53_RS08455	COG2252	PERMEase
CKQ53_RS08460	COG0025	NhaP-type Na H and K H
CKQ53_RS08465	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CKQ53_RS08480	COG1376	ErfK ybiS ycfS ynhG family protein
CKQ53_RS08485	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CKQ53_RS08485	COG1013	pyruvate-flavodoxin oxidoreductase activity
CKQ53_RS08485	COG0674	pyruvate-flavodoxin oxidoreductase activity
CKQ53_RS08485	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CKQ53_RS08495	COG1181	Belongs to the D-alanine--D-alanine ligase family
CKQ53_RS08500	COG2951	lytic endotransglycosylase activity
CKQ53_RS08510	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CKQ53_RS08530	COG3423	Transcriptional regulator
CKQ53_RS08535	COG0582	viral genome integration into host DNA
CKQ53_RS08545	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CKQ53_RS08550	COG2867	negative regulation of translational initiation
CKQ53_RS08555	COG2914	Belongs to the UPF0125 (RnfH) family
CKQ53_RS08560	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CKQ53_RS08570	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CKQ53_RS08575	COG1914	H( )-stimulated, divalent metal cation uptake system
CKQ53_RS08580	COG1942	4-Oxalocrotonate Tautomerase
CKQ53_RS08590	COG0477	Major facilitator Superfamily
CKQ53_RS08595	COG0583	DNA-binding transcription factor activity
CKQ53_RS08600	COG0494	nUDIX hydrolase
CKQ53_RS08605	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CKQ53_RS08610	COG1671	Belongs to the UPF0178 family
CKQ53_RS08615	COG0408	coproporphyrinogen oxidase activity
CKQ53_RS08620	COG0456	acetyltransferase
CKQ53_RS08630	COG2837	iron assimilation
CKQ53_RS08640	COG0577	efflux transmembrane transporter activity
CKQ53_RS08640	COG1136	(ABC) transporter
CKQ53_RS08645	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CKQ53_RS08650	COG0745	RESPONSE REGULATOR receiver
CKQ53_RS08655	COG2205	protein histidine kinase activity
CKQ53_RS08660	COG2190	(PTS) system
CKQ53_RS08665	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CKQ53_RS08670	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CKQ53_RS08680	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
CKQ53_RS08685	COG3115	cell septum assembly
CKQ53_RS08695	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CKQ53_RS08705	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CKQ53_RS08705	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CKQ53_RS08740	COG2862	Uncharacterized protein family, UPF0114
CKQ53_RS08745	COG3265	gluconokinase activity
CKQ53_RS08750	COG0129	dihydroxy-acid dehydratase activity
CKQ53_RS08755	COG3895	Periplasmic Protein
CKQ53_RS08760	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CKQ53_RS08770	COG0242	peptide deformylase activity
CKQ53_RS08810	COG2814	Major facilitator Superfamily
CKQ53_RS08815	COG4975	Glucose uptake
CKQ53_RS08825	COG2207	Transcriptional regulator
CKQ53_RS08835	COG0604	alcohol dehydrogenase
CKQ53_RS08860	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CKQ53_RS08875	COG0583	DNA-binding transcription factor activity
CKQ53_RS08880	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CKQ53_RS08895	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CKQ53_RS08915	COG0205	6-phosphofructokinase activity
CKQ53_RS08920	COG2831	hemolysin activation secretion protein
CKQ53_RS08960	COG0582	viral genome integration into host DNA
CKQ53_RS08970	COG1982	Orn Lys Arg decarboxylase major
CKQ53_RS08980	COG0741	lytic transglycosylase activity
CKQ53_RS08985	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
CKQ53_RS08990	COG1194	a g-specific adenine glycosylase
CKQ53_RS09015	COG3121	Chaperone
CKQ53_RS09025	COG3539	Fimbrial protein
CKQ53_RS09035	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CKQ53_RS09040	COG3171	Protein conserved in bacteria
CKQ53_RS09055	COG0667	Aldo Keto reductase
CKQ53_RS09065	COG0861	Integral membrane protein TerC family
CKQ53_RS09070	COG3066	DNA modification
CKQ53_RS09075	COG0494	nUDIX hydrolase
CKQ53_RS09085	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CKQ53_RS09090	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CKQ53_RS09115	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CKQ53_RS09125	COG1074	ATP-dependent DNA helicase activity
CKQ53_RS09130	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CKQ53_RS09135	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CKQ53_RS09135	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CKQ53_RS09140	COG0860	N-Acetylmuramoyl-L-alanine amidase
CKQ53_RS09160	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CKQ53_RS09165	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CKQ53_RS09170	COG2166	iron-sulfur cluster assembly
CKQ53_RS09175	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CKQ53_RS09185	COG0583	DNA-binding transcription factor activity
CKQ53_RS09190	COG2363	Small membrane protein
CKQ53_RS09195	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
CKQ53_RS09200	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CKQ53_RS09205	COG1611	Belongs to the LOG family
CKQ53_RS09215	COG3098	single-species biofilm formation
CKQ53_RS09240	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CKQ53_RS09255	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CKQ53_RS09260	COG0528	UMP kinase activity
CKQ53_RS09265	COG0233	cytoplasmic translational termination
CKQ53_RS09270	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CKQ53_RS09275	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CKQ53_RS09280	COG0575	Belongs to the CDS family
CKQ53_RS09285	COG0750	zinc metalloprotease
CKQ53_RS09290	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CKQ53_RS09295	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
CKQ53_RS09300	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CKQ53_RS09305	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CKQ53_RS09315	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CKQ53_RS09320	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CKQ53_RS09330	COG0825	malonyl-CoA metabolic process
CKQ53_RS09335	COG0346	lactoylglutathione lyase activity
CKQ53_RS09340	COG0037	tRNA processing
CKQ53_RS09345	COG4568	rho-dependent transcription termination
CKQ53_RS09355	COG4681	YaeQ
CKQ53_RS09365	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CKQ53_RS09400	COG3423	Transcriptional regulator
CKQ53_RS09420	COG2003	Belongs to the UPF0758 family
CKQ53_RS09425	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CKQ53_RS09500	COG0840	transmembrane signaling receptor activity
CKQ53_RS09515	COG2824	Alkylphosphonate utilization operon protein PhnA
CKQ53_RS09540	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CKQ53_RS09545	COG4615	Cyclic peptide transporter
CKQ53_RS09565	COG2974	May be involved in recombination
CKQ53_RS09570	COG0419	ATPase involved in DNA repair
CKQ53_RS09575	COG0420	3'-5' exonuclease activity
CKQ53_RS09585	COG5002	protein histidine kinase activity
CKQ53_RS09590	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CKQ53_RS09605	COG0450	alkyl hydroperoxide reductase
CKQ53_RS09610	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
CKQ53_RS09615	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CKQ53_RS09620	COG0343	queuine tRNA-ribosyltransferase activity
CKQ53_RS09625	COG1862	Preprotein translocase
CKQ53_RS09630	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CKQ53_RS09635	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CKQ53_RS09640	COG4238	major outer membrane lipoprotein
CKQ53_RS09645	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CKQ53_RS09650	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CKQ53_RS09655	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CKQ53_RS09655	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CKQ53_RS09660	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CKQ53_RS09665	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CKQ53_RS09670	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CKQ53_RS09675	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CKQ53_RS09680	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CKQ53_RS09685	COG0142	geranyltranstransferase activity
CKQ53_RS09695	COG0301	tRNA thio-modification
CKQ53_RS09695	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CKQ53_RS09700	COG0693	protein deglycase activity
CKQ53_RS09705	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CKQ53_RS09710	COG1666	GTP binding
CKQ53_RS09715	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CKQ53_RS09715	COG0506	proline dehydrogenase activity
CKQ53_RS09715	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CKQ53_RS09720	COG1126	abc transporter atp-binding protein
CKQ53_RS09730	COG2814	Major facilitator Superfamily
CKQ53_RS09735	COG0109	protoheme IX farnesyltransferase activity
CKQ53_RS09740	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CKQ53_RS09745	COG1845	cytochrome c oxidase, subunit III
CKQ53_RS09750	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CKQ53_RS09755	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CKQ53_RS09760	COG2223	nitrite transmembrane transporter activity
CKQ53_RS09765	COG3056	Lipoprotein
CKQ53_RS09770	COG0271	Belongs to the BolA IbaG family
CKQ53_RS09775	COG0544	peptidyl-prolyl cis-trans isomerase activity
CKQ53_RS09780	COG0740	serine-type endopeptidase activity
CKQ53_RS09785	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CKQ53_RS09790	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CKQ53_RS09795	COG0776	regulation of translation
CKQ53_RS09800	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CKQ53_RS09805	COG1555	photosystem II stabilization
CKQ53_RS09810	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CKQ53_RS09820	COG1522	sequence-specific DNA binding
CKQ53_RS09825	COG1132	(ABC) transporter
CKQ53_RS09830	COG1132	(ABC) transporter
CKQ53_RS09835	COG0347	Belongs to the P(II) protein family
CKQ53_RS09840	COG0004	ammonium transporteR
CKQ53_RS09845	COG1946	Acyl-CoA thioesterase
CKQ53_RS09850	COG3126	Type III secretion system lipoprotein chaperone (YscW)
CKQ53_RS09855	COG3695	enzyme binding
CKQ53_RS09875	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CKQ53_RS09880	COG0254	rRNA binding
CKQ53_RS09885	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CKQ53_RS09890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CKQ53_RS09895	COG1309	transcriptional regulator
CKQ53_RS09900	COG3264	Mechanosensitive ion channel
CKQ53_RS09900	COG1196	nuclear chromosome segregation
CKQ53_RS09920	COG2832	Protein of unknown function (DUF454)
CKQ53_RS09925	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CKQ53_RS09930	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CKQ53_RS09935	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CKQ53_RS09940	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CKQ53_RS09945	COG0326	Molecular chaperone. Has ATPase activity
CKQ53_RS09950	COG0563	adenylate kinase activity
CKQ53_RS09955	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CKQ53_RS09960	COG4651	solute:proton antiporter activity
CKQ53_RS09960	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CKQ53_RS09965	COG0737	Belongs to the 5'-nucleotidase family
CKQ53_RS09975	COG3735	TraB family
CKQ53_RS09980	COG1585	Membrane protein implicated in regulation of membrane protease activity
CKQ53_RS09990	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CKQ53_RS10040	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CKQ53_RS10050	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CKQ53_RS10055	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CKQ53_RS10065	COG0784	Response regulator, receiver
CKQ53_RS10065	COG2205	protein histidine kinase activity
CKQ53_RS10075	COG2198	Histidine kinase
CKQ53_RS10075	COG0642	Histidine kinase
CKQ53_RS10080	COG2223	nitrite transmembrane transporter activity
CKQ53_RS10090	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CKQ53_RS10095	COG0596	Alpha beta hydrolase
CKQ53_RS10105	COG1441	menaquinone biosynthetic process
CKQ53_RS10130	COG3118	belongs to the thioredoxin family
CKQ53_RS10135	COG0300	oxidoreductase activity
CKQ53_RS10140	COG2755	lipolytic protein G-D-S-L family
CKQ53_RS10145	COG4181	ATPase activity
CKQ53_RS10155	COG2200	EAL domain
CKQ53_RS10160	COG3539	Fimbrial protein
CKQ53_RS10165	COG3188	usher protein
CKQ53_RS10170	COG3121	Chaperone
CKQ53_RS10180	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CKQ53_RS10195	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CKQ53_RS10200	COG0765	amino acid transport
CKQ53_RS10205	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CKQ53_RS10215	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CKQ53_RS10225	COG2233	PERMEase
CKQ53_RS10230	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CKQ53_RS10235	COG1393	Belongs to the ArsC family
CKQ53_RS10240	COG4783	chaperone-mediated protein folding
CKQ53_RS10245	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CKQ53_RS10250	COG2716	regulation of RNA biosynthetic process
CKQ53_RS10260	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CKQ53_RS10265	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CKQ53_RS10270	COG2707	UPF0756 membrane protein
CKQ53_RS10275	COG1444	tRNA N-acetyltransferase activity
CKQ53_RS10280	COG0400	carboxylic ester hydrolase activity
CKQ53_RS10290	COG1876	peptidase activity
CKQ53_RS10295	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CKQ53_RS10300	COG1393	Belongs to the ArsC family
CKQ53_RS10310	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CKQ53_RS10315	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CKQ53_RS10320	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CKQ53_RS10325	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CKQ53_RS10330	COG0321	lipoyl(octanoyl) transferase activity
CKQ53_RS10340	COG1686	Belongs to the peptidase S11 family
CKQ53_RS10345	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CKQ53_RS10350	COG0772	Belongs to the SEDS family
CKQ53_RS10355	COG0768	penicillin binding
CKQ53_RS10360	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CKQ53_RS10365	COG0799	negative regulation of ribosome biogenesis
CKQ53_RS10370	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CKQ53_RS10375	COG1466	dna polymerase III delta subunit
CKQ53_RS10380	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
CKQ53_RS10385	COG0495	leucyl-tRNA aminoacylation
CKQ53_RS10395	COG2888	peptidyl-tyrosine sulfation
CKQ53_RS10400	COG1126	abc transporter atp-binding protein
CKQ53_RS10405	COG0765	amino acid transport
CKQ53_RS10410	COG0765	amino acid transport
CKQ53_RS10420	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CKQ53_RS10425	COG4535	Mg2 and Co2 transporter CorC
CKQ53_RS10430	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CKQ53_RS10435	COG1702	phosphate starvation-inducible protein PhoH
CKQ53_RS10440	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CKQ53_RS10445	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CKQ53_RS10490	COG0367	asparagine synthase
CKQ53_RS10495	COG1940	carbohydrate kinase activity
CKQ53_RS10495	COG1846	Transcriptional regulator
CKQ53_RS10500	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CKQ53_RS10505	COG0363	glucosamine-6-phosphate deaminase activity
CKQ53_RS10510	COG2190	(PTS) system
CKQ53_RS10510	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CKQ53_RS10510	COG1263	PTS System
CKQ53_RS10515	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CKQ53_RS10520	COG0735	belongs to the Fur family
CKQ53_RS10530	COG0840	transmembrane signaling receptor activity
CKQ53_RS10540	COG0596	Alpha beta hydrolase
CKQ53_RS10545	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
CKQ53_RS10550	COG0033	Phosphoglucomutase
CKQ53_RS10560	COG0745	RESPONSE REGULATOR receiver
CKQ53_RS10575	COG3272	Protein of unknown function (DUF1722)
CKQ53_RS10580	COG0415	Belongs to the DNA photolyase family
CKQ53_RS10585	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CKQ53_RS10590	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CKQ53_RS10595	COG1984	allophanate hydrolase subunit 2
CKQ53_RS10600	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CKQ53_RS10605	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CKQ53_RS10610	COG0372	Belongs to the citrate synthase family
CKQ53_RS10620	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CKQ53_RS10625	COG1053	succinate dehydrogenase
CKQ53_RS10630	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CKQ53_RS10635	COG0567	Dehydrogenase, E1 component
CKQ53_RS10640	COG0508	dehydrogenase complex catalyzes the overall conversion of
CKQ53_RS10645	COG0045	succinate-CoA ligase (ADP-forming) activity
CKQ53_RS10650	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CKQ53_RS10655	COG1271	oxidase subunit
CKQ53_RS10660	COG1294	oxidase, subunit
CKQ53_RS10665	COG4890	Cyd operon protein YbgT
CKQ53_RS10670	COG3790	cyd operon protein YbgE
CKQ53_RS10675	COG0824	Thioesterase
CKQ53_RS10680	COG0811	peptide transport
CKQ53_RS10685	COG0848	biopolymer transport protein
CKQ53_RS10690	COG3064	Membrane
CKQ53_RS10690	COG3064	Membrane
CKQ53_RS10695	COG0823	Involved in the tonB-independent uptake of proteins
CKQ53_RS10700	COG2885	chlorophyll binding
CKQ53_RS10705	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
CKQ53_RS10725	COG3201	nicotinamide mononucleotide transporter
CKQ53_RS10730	COG1230	cation diffusion facilitator family transporter
CKQ53_RS10735	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CKQ53_RS10745	COG2017	converts alpha-aldose to the beta-anomer
CKQ53_RS10750	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CKQ53_RS10755	COG1119	ATPase activity
CKQ53_RS10760	COG2005	Transcriptional regulator
CKQ53_RS10760	COG3585	molybdate ion transport
CKQ53_RS10770	COG0725	ABC transporter, periplasmic molybdate-binding protein
CKQ53_RS10775	COG4149	molybdate abc transporter
CKQ53_RS10780	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CKQ53_RS10785	COG0561	phosphatase activity
CKQ53_RS10790	COG2706	6-phosphogluconolactonase activity
CKQ53_RS10810	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CKQ53_RS10810	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CKQ53_RS10820	COG0572	uridine kinase
CKQ53_RS10825	COG0717	Belongs to the dCTP deaminase family
CKQ53_RS10830	COG2982	Protein involved in outer membrane biogenesis
CKQ53_RS10840	COG1253	flavin adenine dinucleotide binding
CKQ53_RS10870	COG0438	transferase activity, transferring glycosyl groups
CKQ53_RS10880	COG2244	polysaccharide biosynthetic process
CKQ53_RS10885	COG0463	Glycosyl transferase, family 2
CKQ53_RS10895	COG0438	transferase activity, transferring glycosyl groups
CKQ53_RS10930	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CKQ53_RS10960	COG2990	Protein conserved in bacteria
CKQ53_RS10965	COG3720	iron ion transport
CKQ53_RS10970	COG4558	Periplasmic binding protein
CKQ53_RS10975	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CKQ53_RS10980	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CKQ53_RS10990	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CKQ53_RS10995	COG4251	negative regulation of phosphorylation
CKQ53_RS10995	COG3706	GGDEF domain
CKQ53_RS10995	COG5001	Diguanylate cyclase
CKQ53_RS10995	COG2203	Gaf domain
CKQ53_RS11000	COG0840	transmembrane signaling receptor activity
CKQ53_RS11025	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CKQ53_RS11025	COG3008	intermembrane lipid transfer
CKQ53_RS11030	COG2995	paraquat-inducible protein a
CKQ53_RS11035	COG2995	paraquat-inducible protein a
CKQ53_RS11045	COG1309	transcriptional regulator
CKQ53_RS11050	COG2197	response regulator
CKQ53_RS11060	COG0436	Aminotransferase
CKQ53_RS11075	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CKQ53_RS11095	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CKQ53_RS11100	COG2011	ABC-type metal ion transport system permease component
CKQ53_RS11110	COG0477	Major facilitator Superfamily
CKQ53_RS11120	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CKQ53_RS11125	COG1414	Transcriptional regulator
CKQ53_RS11135	COG2375	cellular response to nickel ion
CKQ53_RS11145	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CKQ53_RS11160	COG1695	Transcriptional regulator
CKQ53_RS11175	COG1811	Na channel or pump
CKQ53_RS11185	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CKQ53_RS11190	COG0583	DNA-binding transcription factor activity
CKQ53_RS11200	COG0561	phosphatase activity
CKQ53_RS11210	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CKQ53_RS11220	COG1733	regulation of RNA biosynthetic process
CKQ53_RS11225	COG0702	epimerase
CKQ53_RS11230	COG1028	Short-chain dehydrogenase reductase Sdr
CKQ53_RS11230	COG0604	alcohol dehydrogenase
CKQ53_RS11230	COG3321	synthase
CKQ53_RS11260	COG1136	(ABC) transporter
CKQ53_RS11280	COG0577	efflux transmembrane transporter activity
CKQ53_RS11280	COG1136	(ABC) transporter
CKQ53_RS11300	COG3038	cytochrome b561
CKQ53_RS11305	COG0484	heat shock protein binding
CKQ53_RS11315	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CKQ53_RS11325	COG1012	belongs to the aldehyde dehydrogenase family
CKQ53_RS11330	COG3724	N-succinylarginine dihydrolase activity
CKQ53_RS11335	COG2988	succinylglutamate desuccinylase activity
CKQ53_RS11340	COG4215	(ABC) transporter
CKQ53_RS11345	COG4160	amino acid transport
CKQ53_RS11350	COG4598	ABC transporter
CKQ53_RS11365	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CKQ53_RS11370	COG0601	transmembrane transport
CKQ53_RS11380	COG2217	Heavy metal translocating P-type atpase
CKQ53_RS11390	COG1937	Protein conserved in bacteria
CKQ53_RS11395	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
CKQ53_RS11400	COG0835	chemotaxis
CKQ53_RS11400	COG0784	Response regulator, receiver
CKQ53_RS11405	COG2814	Major facilitator Superfamily
CKQ53_RS11415	COG0583	DNA-binding transcription factor activity
CKQ53_RS11425	COG0309	Hydrogenase expression formation protein (HypE)
CKQ53_RS11435	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CKQ53_RS11440	COG2223	nitrite transmembrane transporter activity
CKQ53_RS11445	COG1309	transcriptional regulator
CKQ53_RS11475	COG1309	transcriptional regulator
CKQ53_RS11520	COG1301	dicarboxylic acid transport
CKQ53_RS11525	COG3383	formate dehydrogenase (NAD+) activity
CKQ53_RS11530	COG0697	spore germination
CKQ53_RS11535	COG0583	DNA-binding transcription factor activity
CKQ53_RS11540	COG1301	dicarboxylic acid transport
CKQ53_RS11550	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CKQ53_RS11555	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CKQ53_RS11565	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CKQ53_RS11570	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CKQ53_RS11590	COG0019	diaminopimelate decarboxylase activity
CKQ53_RS11595	COG0477	Major facilitator Superfamily
CKQ53_RS11600	COG4264	IucA IucC family
CKQ53_RS11610	COG4264	IucA IucC family
CKQ53_RS11615	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CKQ53_RS11620	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CKQ53_RS11625	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CKQ53_RS11630	COG1120	ATPase activity
CKQ53_RS11635	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CKQ53_RS11640	COG0531	amino acid
CKQ53_RS11645	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CKQ53_RS11650	COG0531	amino acid
CKQ53_RS11655	COG1280	lysine exporter protein (LysE YggA)
CKQ53_RS11675	COG0454	-acetyltransferase
CKQ53_RS11685	COG0371	Dehydrogenase
CKQ53_RS11695	COG1012	belongs to the aldehyde dehydrogenase family
CKQ53_RS11700	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CKQ53_RS11705	COG3842	ATPase activity
CKQ53_RS11710	COG1176	ABC-type spermidine putrescine transport system, permease component I
CKQ53_RS11715	COG1177	transmembrane transport
CKQ53_RS11720	COG1012	belongs to the aldehyde dehydrogenase family
CKQ53_RS11725	COG2271	Major facilitator Superfamily
CKQ53_RS11730	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CKQ53_RS11735	COG2211	Major facilitator Superfamily
CKQ53_RS11740	COG2267	carboxylic ester hydrolase activity
CKQ53_RS11745	COG2197	response regulator
CKQ53_RS11750	COG0601	transmembrane transport
CKQ53_RS11755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CKQ53_RS11760	COG0444	Belongs to the ABC transporter superfamily
CKQ53_RS11765	COG4608	Belongs to the ABC transporter superfamily
CKQ53_RS11775	COG4993	Dehydrogenase
CKQ53_RS11780	COG3604	Transcriptional regulator
CKQ53_RS11805	COG0588	phosphoglycerate mutase activity
CKQ53_RS11810	COG1309	transcriptional regulator
CKQ53_RS11825	COG1560	Kdo2-lipid A biosynthetic process
CKQ53_RS11830	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CKQ53_RS11850	COG3228	Belongs to the MtfA family
CKQ53_RS11895	COG0643	Histidine kinase
CKQ53_RS11895	COG2198	Histidine kinase
CKQ53_RS11900	COG0835	chemotaxis
CKQ53_RS11905	COG0840	transmembrane signaling receptor activity
CKQ53_RS11910	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CKQ53_RS11915	COG2201	protein-glutamate methylesterase activity
CKQ53_RS11920	COG0745	RESPONSE REGULATOR receiver
CKQ53_RS11930	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CKQ53_RS11935	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CKQ53_RS11945	COG3418	PFAM FlgN family protein
CKQ53_RS11950	COG2747	anti-sigma28 factor FlgM
CKQ53_RS11960	COG1815	bacterial-type flagellum-dependent cell motility
CKQ53_RS11965	COG1558	bacterial-type flagellum-dependent cell motility
CKQ53_RS11970	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CKQ53_RS11975	COG1749	Flagellar hook protein flgE
CKQ53_RS11995	COG1706	bacterial-type flagellum-dependent cell motility
CKQ53_RS12005	COG1256	bacterial-type flagellum assembly
CKQ53_RS12010	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CKQ53_RS12015	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CKQ53_RS12030	COG1677	Flagellar hook-basal body complex protein FliE
CKQ53_RS12040	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CKQ53_RS12045	COG1317	bacterial-type flagellum organization
CKQ53_RS12060	COG3144	bacterial-type flagellum assembly
CKQ53_RS12065	COG1580	Controls the rotational direction of flagella during chemotaxis
CKQ53_RS12070	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CKQ53_RS12105	COG1216	Glycosyl transferase, family 2
CKQ53_RS12105	COG0438	transferase activity, transferring glycosyl groups
CKQ53_RS12115	COG1191	sigma factor activity
CKQ53_RS12125	COG1702	phosphate starvation-inducible protein PhoH
CKQ53_RS12170	COG1067	ATP-dependent peptidase activity
CKQ53_RS12210	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
CKQ53_RS12215	COG2943	transferase activity, transferring hexosyl groups
CKQ53_RS12220	COG1560	Kdo2-lipid A biosynthetic process
CKQ53_RS12225	COG1054	Belongs to the UPF0176 family
CKQ53_RS12230	COG2353	YceI-like domain
CKQ53_RS12235	COG3038	cytochrome b561
CKQ53_RS12250	COG0418	dihydroorotase activity
CKQ53_RS12260	COG1530	ribonuclease E activity
CKQ53_RS12270	COG0564	pseudouridine synthase activity
CKQ53_RS12280	COG1399	metal-binding, possibly nucleic acid-binding protein
CKQ53_RS12285	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CKQ53_RS12290	COG0416	fatty acid biosynthetic process
CKQ53_RS12295	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CKQ53_RS12310	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CKQ53_RS12315	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CKQ53_RS12320	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CKQ53_RS12325	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CKQ53_RS12335	COG0470	DNA polymerase III
CKQ53_RS12340	COG0084	hydrolase, TatD family'
CKQ53_RS12345	COG1263	PTS System
CKQ53_RS12345	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CKQ53_RS12355	COG0537	adenosine 5'-monophosphoramidase activity
CKQ53_RS12360	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
CKQ53_RS12370	COG1472	Belongs to the glycosyl hydrolase 3 family
CKQ53_RS12375	COG1252	NADH dehydrogenase
CKQ53_RS12380	COG3134	Outer membrane lipoprotein
CKQ53_RS12390	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CKQ53_RS12395	COG4591	ABC-type transport system involved in lipoprotein release permease component
CKQ53_RS12400	COG1136	(ABC) transporter
CKQ53_RS12405	COG4591	ABC-type transport system involved in lipoprotein release permease component
CKQ53_RS12420	COG0791	NLP P60 protein
CKQ53_RS12430	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CKQ53_RS12435	COG2989	Protein conserved in bacteria
CKQ53_RS12440	COG3108	Peptidase M15
CKQ53_RS12445	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CKQ53_RS12450	COG1448	Aminotransferase
CKQ53_RS12460	COG0017	Asparaginyl-tRNA synthetase
CKQ53_RS12465	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CKQ53_RS12470	COG0308	aminopeptidase N
CKQ53_RS12475	COG1116	anion transmembrane transporter activity
CKQ53_RS12480	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CKQ53_RS12485	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CKQ53_RS12490	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CKQ53_RS12495	COG0431	NADPH-dependent FMN reductase
CKQ53_RS12500	COG0167	dihydroorotate dehydrogenase activity
CKQ53_RS12510	COG0116	Belongs to the methyltransferase superfamily
CKQ53_RS12510	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CKQ53_RS12515	COG0488	(ABC) transporter
CKQ53_RS12520	COG2995	paraquat-inducible protein a
CKQ53_RS12525	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CKQ53_RS12525	COG3008	intermembrane lipid transfer
CKQ53_RS12530	COG3009	Protein conserved in bacteria
CKQ53_RS12535	COG3130	regulation of translation
CKQ53_RS12540	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CKQ53_RS12545	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CKQ53_RS12550	COG0574	Belongs to the PEP-utilizing enzyme family
CKQ53_RS12550	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CKQ53_RS12555	COG0628	permease
CKQ53_RS12560	COG0277	FAD linked oxidase domain protein
CKQ53_RS12560	COG0247	lactate metabolic process
CKQ53_RS12565	COG2050	protein possibly involved in aromatic compounds catabolism
CKQ53_RS12575	COG0316	Belongs to the HesB IscA family
CKQ53_RS12580	COG0719	Fe-S assembly protein
CKQ53_RS12585	COG0396	ATPase activity
CKQ53_RS12590	COG0719	Fe-S assembly protein
CKQ53_RS12595	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CKQ53_RS12600	COG2166	iron-sulfur cluster assembly
CKQ53_RS12605	COG1376	ErfK ybiS ycfS ynhG family protein
CKQ53_RS12605	COG1388	LysM domain
CKQ53_RS12610	COG4238	major outer membrane lipoprotein
CKQ53_RS12655	COG2197	response regulator
CKQ53_RS12660	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CKQ53_RS12665	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CKQ53_RS12675	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CKQ53_RS12685	COG1294	oxidase, subunit
CKQ53_RS12690	COG1271	oxidase subunit
CKQ53_RS12695	COG0300	oxidoreductase activity
CKQ53_RS12705	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CKQ53_RS12710	COG2814	Major facilitator Superfamily
CKQ53_RS12720	COG0287	Prephenate dehydrogenase
CKQ53_RS12720	COG1605	Chorismate mutase
CKQ53_RS12750	COG0583	DNA-binding transcription factor activity
CKQ53_RS12755	COG1028	Short-chain dehydrogenase reductase Sdr
CKQ53_RS12760	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CKQ53_RS12765	COG1012	belongs to the aldehyde dehydrogenase family
CKQ53_RS12775	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CKQ53_RS12785	COG0534	Mate efflux family protein
CKQ53_RS12790	COG0307	riboflavin synthase, alpha
CKQ53_RS12795	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CKQ53_RS12800	COG1609	Transcriptional regulator
CKQ53_RS12810	COG0791	NLP P60 protein
CKQ53_RS12815	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CKQ53_RS12820	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CKQ53_RS12825	COG0346	lactoylglutathione lyase activity
CKQ53_RS12830	COG3313	Fe-S protein
CKQ53_RS12845	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CKQ53_RS12850	COG3895	Periplasmic Protein
CKQ53_RS12855	COG0259	pyridoxamine-phosphate oxidase activity
CKQ53_RS12860	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CKQ53_RS12865	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
CKQ53_RS12885	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CKQ53_RS12890	COG0671	phosphoesterase, PA-phosphatase related
CKQ53_RS12895	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
CKQ53_RS12900	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CKQ53_RS12905	COG0284	orotidine-5'-phosphate decarboxylase activity
CKQ53_RS12910	COG0023	Translation Initiation Factor
CKQ53_RS12920	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
CKQ53_RS12925	COG0243	molybdopterin cofactor binding
CKQ53_RS12930	COG1263	PTS System
CKQ53_RS12930	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CKQ53_RS12935	COG1486	melibiose metabolic process
CKQ53_RS12945	COG0583	DNA-binding transcription factor activity
CKQ53_RS12950	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CKQ53_RS13025	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CKQ53_RS13140	COG0484	heat shock protein binding
CKQ53_RS13335	COG4168	peptide transport system, permease
CKQ53_RS13340	COG4166	transmembrane transport
CKQ53_RS13345	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CKQ53_RS13350	COG1842	Phage shock protein A
CKQ53_RS13360	COG1983	PspC domain protein
CKQ53_RS13365	COG3106	COG3106 Predicted ATPase
CKQ53_RS13370	COG3768	UPF0283 membrane protein
CKQ53_RS13375	COG2807	transmembrane transport
CKQ53_RS13400	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CKQ53_RS13405	COG4166	transmembrane transport
CKQ53_RS13410	COG0598	Magnesium transport protein CorA
CKQ53_RS13420	COG0037	tRNA processing
CKQ53_RS13430	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CKQ53_RS13435	COG2911	Protein conserved in bacteria
CKQ53_RS13445	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CKQ53_RS13450	COG1643	Atp-dependent helicase
CKQ53_RS13465	COG3591	Belongs to the peptidase S1B family
CKQ53_RS13475	COG2205	protein histidine kinase activity
CKQ53_RS13480	COG0745	RESPONSE REGULATOR receiver
CKQ53_RS13485	COG0659	secondary active sulfate transmembrane transporter activity
CKQ53_RS13490	COG0387	Pfam Sodium calcium exchanger
CKQ53_RS13495	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
CKQ53_RS13500	COG0601	transmembrane transport
CKQ53_RS13505	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CKQ53_RS13510	COG0444	Belongs to the ABC transporter superfamily
CKQ53_RS13515	COG4608	Belongs to the ABC transporter superfamily
CKQ53_RS13535	COG2261	transglycosylase associated protein
CKQ53_RS13540	COG1454	alcohol dehydrogenase
CKQ53_RS13550	COG3842	ATPase activity
CKQ53_RS13560	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CKQ53_RS13565	COG1012	belongs to the aldehyde dehydrogenase family
CKQ53_RS13575	COG1176	ABC-type spermidine putrescine transport system, permease component I
CKQ53_RS13580	COG0395	ABC-type sugar transport system, permease component
CKQ53_RS13585	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CKQ53_RS13595	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CKQ53_RS13600	COG4792	protein secretion
CKQ53_RS13610	COG4794	Type iii secretion
CKQ53_RS13685	COG4669	(LipO)protein
CKQ53_RS13735	COG0583	DNA-binding transcription factor activity
CKQ53_RS13740	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CKQ53_RS13745	COG4658	electron transport chain
CKQ53_RS13750	COG4656	Part of a membrane complex involved in electron transport
CKQ53_RS13755	COG2723	6-phospho-beta-galactosidase activity
CKQ53_RS13760	COG0673	inositol 2-dehydrogenase activity
CKQ53_RS13765	COG0385	Bile acid
CKQ53_RS13770	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CKQ53_RS13775	COG5339	Protein conserved in bacteria
CKQ53_RS13780	COG1482	cell wall glycoprotein biosynthetic process
CKQ53_RS13785	COG0114	fumarate hydratase activity
CKQ53_RS13795	COG2814	Major facilitator Superfamily
CKQ53_RS13800	COG0583	DNA-binding transcription factor activity
CKQ53_RS13805	COG1940	carbohydrate kinase activity
CKQ53_RS13810	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CKQ53_RS13815	COG3459	Glycosyltransferase 36 associated
CKQ53_RS13840	COG4221	oxidoreductase activity
CKQ53_RS13845	COG2226	methyltransferase
CKQ53_RS13855	COG1215	transferase activity, transferring glycosyl groups
CKQ53_RS13865	COG2423	ornithine cyclodeaminase activity
CKQ53_RS13870	COG2066	Belongs to the glutaminase family
CKQ53_RS13875	COG4305	rare lipoprotein A
CKQ53_RS13885	COG0840	transmembrane signaling receptor activity
CKQ53_RS13900	COG0583	DNA-binding transcription factor activity
CKQ53_RS13925	COG1764	response to oxidative stress
CKQ53_RS13930	COG1902	pentaerythritol trinitrate reductase activity
CKQ53_RS13975	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CKQ53_RS13990	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CKQ53_RS13995	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CKQ53_RS14010	COG2912	Transglutaminase-like superfamily
CKQ53_RS14020	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CKQ53_RS14025	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CKQ53_RS14030	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CKQ53_RS14035	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CKQ53_RS14050	COG0193	aminoacyl-tRNA hydrolase activity
CKQ53_RS14055	COG0012	GTP binding
CKQ53_RS14085	COG4221	oxidoreductase activity
CKQ53_RS14090	COG0583	DNA-binding transcription factor activity
CKQ53_RS14105	COG2199	diguanylate cyclase activity
CKQ53_RS14105	COG2202	Pas domain
CKQ53_RS14105	COG2200	EAL domain
CKQ53_RS14110	COG0277	FAD linked oxidase domain protein
CKQ53_RS14115	COG1283	sodium-dependent phosphate transmembrane transporter activity
CKQ53_RS14130	COG4149	molybdate abc transporter
CKQ53_RS14145	COG2188	Transcriptional regulator
CKQ53_RS14165	COG5297	Belongs to the glycosyl hydrolase family 6
CKQ53_RS14185	COG0616	signal peptide processing
CKQ53_RS14190	COG1028	Short-chain dehydrogenase reductase Sdr
CKQ53_RS14195	COG1187	pseudouridine synthase activity
CKQ53_RS14200	COG0009	L-threonylcarbamoyladenylate synthase
CKQ53_RS14205	COG0613	PHP domain protein
CKQ53_RS14215	COG0512	Glutamine amidotransferase of anthranilate synthase
CKQ53_RS14220	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CKQ53_RS14230	COG0133	tryptophan synthase activity
CKQ53_RS14235	COG0159	tryptophan synthase activity
CKQ53_RS14240	COG0727	PFAM Uncharacterised protein family (UPF0153)
CKQ53_RS14250	COG2917	probably involved in intracellular septation
CKQ53_RS14265	COG2350	Protein conserved in bacteria
CKQ53_RS14275	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CKQ53_RS14290	COG0444	Belongs to the ABC transporter superfamily
CKQ53_RS14295	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CKQ53_RS14300	COG0601	transmembrane transport
CKQ53_RS14325	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CKQ53_RS14330	COG0745	RESPONSE REGULATOR receiver
CKQ53_RS14335	COG1752	Esterase of the alpha-beta hydrolase superfamily
CKQ53_RS14340	COG3012	SEC-C Motif Domain Protein
CKQ53_RS14345	COG0788	formyltetrahydrofolate deformylase activity
CKQ53_RS14360	COG2860	membrane
CKQ53_RS14365	COG0708	Exodeoxyribonuclease III
CKQ53_RS14375	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CKQ53_RS14380	COG0778	Nitroreductase
CKQ53_RS14390	COG0252	asparaginase activity
CKQ53_RS14395	COG1335	isochorismatase
CKQ53_RS14400	COG3139	Protein of unknown function (DUF1315)
CKQ53_RS14405	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CKQ53_RS14415	COG0676	glucose-6-phosphate 1-epimerase activity
CKQ53_RS14420	COG3713	MltA-interacting MipA family protein
CKQ53_RS14425	COG2766	serine protein kinase
CKQ53_RS14430	COG2718	Belongs to the UPF0229 family
CKQ53_RS14435	COG0444	Belongs to the ABC transporter superfamily
CKQ53_RS14445	COG0747	negative chemotaxis
CKQ53_RS14455	COG2719	SpoVR family
CKQ53_RS14465	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CKQ53_RS14485	COG2983	Belongs to the UPF0260 family
CKQ53_RS14490	COG0179	Fumarylacetoacetate (FAA) hydrolase
CKQ53_RS14500	COG0850	regulation of cytokinetic process
CKQ53_RS14505	COG2894	cell division
CKQ53_RS14510	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CKQ53_RS14515	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CKQ53_RS14520	COG0318	PFAM AMP-dependent synthetase and ligase
CKQ53_RS14525	COG3065	identical protein binding
CKQ53_RS14555	COG0494	nUDIX hydrolase
CKQ53_RS14560	COG1760	l-serine dehydratase
CKQ53_RS14570	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CKQ53_RS14570	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CKQ53_RS14575	COG3715	PTS system
CKQ53_RS14580	COG3716	PTS system mannose fructose sorbose family IID component
CKQ53_RS14585	COG4811	Protein of unknown function (DUF986)
CKQ53_RS14590	COG1971	Probably functions as a manganese efflux pump
CKQ53_RS14595	COG2226	methyltransferase
CKQ53_RS14610	COG0803	Belongs to the bacterial solute-binding protein 9 family
CKQ53_RS14615	COG1121	(ABC) transporter
CKQ53_RS14620	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CKQ53_RS14625	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CKQ53_RS14630	COG3001	Fructosamine kinase
CKQ53_RS14640	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CKQ53_RS14650	COG1988	membrane-bound metal-dependent
CKQ53_RS14655	COG1823	symporter activity
CKQ53_RS14660	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CKQ53_RS14665	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CKQ53_RS14680	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CKQ53_RS14680	COG0072	phenylalanine-tRNA ligase activity
CKQ53_RS14685	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CKQ53_RS14700	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CKQ53_RS14705	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CKQ53_RS14715	COG0501	Belongs to the peptidase M48B family
CKQ53_RS14730	COG0538	isocitrate dehydrogenase activity
CKQ53_RS14735	COG1187	pseudouridine synthase activity
CKQ53_RS14745	COG0482	sulfurtransferase activity
CKQ53_RS14750	COG2915	High frequency lysogenization protein hflD homolog
CKQ53_RS14755	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CKQ53_RS14760	COG0745	RESPONSE REGULATOR receiver
CKQ53_RS14765	COG2205	protein histidine kinase activity
CKQ53_RS14770	COG2850	peptidyl-arginine hydroxylation
CKQ53_RS14775	COG2195	Cleaves the N-terminal amino acid of tripeptides
CKQ53_RS14800	COG0793	Belongs to the peptidase S41A family
CKQ53_RS14805	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
CKQ53_RS14810	COG1956	GAF domain-containing protein
CKQ53_RS14815	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CKQ53_RS14815	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
CKQ53_RS14835	COG2840	Smr protein MutS2
CKQ53_RS14850	COG0402	S-adenosylhomocysteine deaminase activity
CKQ53_RS14900	COG1528	Iron-storage protein
CKQ53_RS14910	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CKQ53_RS14920	COG0800	Aldolase
CKQ53_RS14925	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CKQ53_RS14930	COG1737	Transcriptional regulator
CKQ53_RS14935	COG0469	pyruvate kinase activity
CKQ53_RS14945	COG1560	Kdo2-lipid A biosynthetic process
CKQ53_RS14950	COG0739	heme binding
CKQ53_RS14955	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CKQ53_RS14960	COG1121	(ABC) transporter
CKQ53_RS14965	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CKQ53_RS14970	COG2255	four-way junction helicase activity
CKQ53_RS14975	COG0632	four-way junction helicase activity
CKQ53_RS14985	COG0217	transcriptional regulatory protein
CKQ53_RS14990	COG0494	nUDIX hydrolase
CKQ53_RS14995	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CKQ53_RS15000	COG1335	isochorismatase
CKQ53_RS15005	COG1801	Protein of unknown function DUF72
CKQ53_RS15010	COG3788	relative of glutathione S-transferase, MAPEG superfamily
CKQ53_RS15015	COG2226	methyltransferase
CKQ53_RS15020	COG0500	methyltransferase
CKQ53_RS15025	COG3142	Participates in the control of copper homeostasis
CKQ53_RS15030	COG3102	Protein conserved in bacteria
CKQ53_RS15035	COG0018	arginyl-trna synthetase
CKQ53_RS15040	COG0728	peptidoglycan biosynthetic process
CKQ53_RS15045	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CKQ53_RS15050	COG0477	Major facilitator Superfamily
CKQ53_RS15055	COG2999	glutathione oxidoreductase activity
CKQ53_RS15065	COG3381	protein complex oligomerization
CKQ53_RS15105	COG1966	Carbon starvation protein
CKQ53_RS15110	COG2879	small protein
CKQ53_RS15115	COG0523	cobalamin synthesis protein
CKQ53_RS15120	COG3279	Response regulator of the LytR AlgR family
CKQ53_RS15125	COG3275	phosphorelay sensor kinase activity
CKQ53_RS15130	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
CKQ53_RS15135	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
CKQ53_RS15140	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
CKQ53_RS15145	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CKQ53_RS15150	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CKQ53_RS15155	COG3173	Aminoglycoside phosphotransferase
CKQ53_RS15165	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CKQ53_RS15170	COG2835	tetraacyldisaccharide 4'-kinase activity
CKQ53_RS15175	COG1663	tetraacyldisaccharide 4'-kinase activity
CKQ53_RS15180	COG1132	(ABC) transporter
CKQ53_RS15195	COG2333	competence protein COMEC
CKQ53_RS15195	COG0658	competence protein
CKQ53_RS15200	COG2926	Belongs to the UPF0265 family
CKQ53_RS15205	COG0247	lactate metabolic process
CKQ53_RS15210	COG1139	Iron-sulfur cluster binding protein
CKQ53_RS15215	COG1556	Lactate utilization protein
CKQ53_RS15220	COG2925	Exonuclease
CKQ53_RS15225	COG0531	amino acid
CKQ53_RS15230	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
CKQ53_RS15235	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
CKQ53_RS15255	COG3052	prosthetic group binding
CKQ53_RS15260	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
CKQ53_RS15265	COG0179	Fumarylacetoacetate (FAA) hydrolase
CKQ53_RS15270	COG3493	citrate carrier protein
CKQ53_RS15285	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CKQ53_RS15290	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CKQ53_RS15295	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CKQ53_RS15300	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CKQ53_RS15305	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CKQ53_RS15305	COG0131	Imidazoleglycerol-phosphate dehydratase
CKQ53_RS15310	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CKQ53_RS15315	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CKQ53_RS15320	COG0107	imidazoleglycerol-phosphate synthase activity
CKQ53_RS15330	COG0776	regulation of translation
CKQ53_RS15335	COG0539	negative regulation of cytoplasmic translation
CKQ53_RS15340	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CKQ53_RS15345	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CKQ53_RS15350	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CKQ53_RS15355	COG1944	ATP diphosphatase activity
CKQ53_RS15360	COG2116	formate transmembrane transporter activity
CKQ53_RS15365	COG1882	Formate acetyltransferase
CKQ53_RS15375	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CKQ53_RS15380	COG2814	Major facilitator Superfamily
CKQ53_RS15385	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CKQ53_RS15390	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CKQ53_RS15395	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CKQ53_RS15400	COG3107	peptidoglycan biosynthetic process
CKQ53_RS15400	COG1674	ftsk spoiiie
CKQ53_RS15405	COG1522	sequence-specific DNA binding
CKQ53_RS15410	COG0492	ferredoxin-NADP+ reductase activity
CKQ53_RS15415	COG4988	ABC transporter
CKQ53_RS15420	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CKQ53_RS15425	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CKQ53_RS15430	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CKQ53_RS15445	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CKQ53_RS15450	COG1278	Cold shock
CKQ53_RS15460	COG3593	DNA synthesis involved in DNA repair
CKQ53_RS15465	COG2431	L-lysine efflux transmembrane transporter activity
CKQ53_RS15470	COG3023	N-Acetylmuramoyl-L-alanine amidase
CKQ53_RS15475	COG0393	Putative heavy-metal-binding
CKQ53_RS15480	COG1126	abc transporter atp-binding protein
CKQ53_RS15485	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CKQ53_RS15490	COG4215	(ABC) transporter
CKQ53_RS15495	COG4160	amino acid transport
CKQ53_RS15500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CKQ53_RS15505	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CKQ53_RS15515	COG1177	transmembrane transport
CKQ53_RS15520	COG1176	ABC-type spermidine putrescine transport system, permease component I
CKQ53_RS15525	COG3842	ATPase activity
CKQ53_RS15530	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CKQ53_RS15555	COG0569	domain protein
CKQ53_RS15555	COG2985	domain, Protein
CKQ53_RS15560	COG1349	DNA-binding transcription factor activity
CKQ53_RS15565	COG1686	Belongs to the peptidase S11 family
CKQ53_RS15570	COG2011	ABC-type metal ion transport system permease component
CKQ53_RS15575	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CKQ53_RS15580	COG1464	Belongs to the NlpA lipoprotein family
CKQ53_RS15585	COG0625	glutathione transferase activity
CKQ53_RS15590	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CKQ53_RS15595	COG2949	membrane
CKQ53_RS15600	COG2311	Membrane
CKQ53_RS15605	COG0302	gtp cyclohydrolase
CKQ53_RS15610	COG0840	transmembrane signaling receptor activity
CKQ53_RS15615	COG0840	transmembrane signaling receptor activity
CKQ53_RS15625	COG1902	pentaerythritol trinitrate reductase activity
CKQ53_RS15630	COG0583	DNA-binding transcription factor activity
CKQ53_RS15650	COG0371	Dehydrogenase
CKQ53_RS15655	COG1129	ABC transporter
CKQ53_RS15660	COG1172	Belongs to the binding-protein-dependent transport system permease family
CKQ53_RS15670	COG0833	amino acid
CKQ53_RS15675	COG0583	DNA-binding transcription factor activity
CKQ53_RS15680	COG2855	membrane
CKQ53_RS15685	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CKQ53_RS15690	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CKQ53_RS15690	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CKQ53_RS15690	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CKQ53_RS15695	COG1105	Belongs to the carbohydrate kinase PfkB family
CKQ53_RS15700	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CKQ53_RS15700	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CKQ53_RS15715	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CKQ53_RS15720	COG0523	cobalamin synthesis protein
CKQ53_RS15725	COG0671	phosphoesterase, PA-phosphatase related
CKQ53_RS15730	COG0791	NLP P60 protein
CKQ53_RS15735	COG4166	transmembrane transport
CKQ53_RS15740	COG4174	ABC transporter (Permease)
CKQ53_RS15745	COG4239	(ABC) transporter, permease
CKQ53_RS15750	COG4172	Belongs to the ABC transporter superfamily
CKQ53_RS15760	COG2814	Major facilitator Superfamily
CKQ53_RS15765	COG1187	pseudouridine synthase activity
CKQ53_RS15770	COG1061	Type III restriction enzyme res subunit
CKQ53_RS15775	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CKQ53_RS15780	COG2223	nitrite transmembrane transporter activity
CKQ53_RS15785	COG3279	Response regulator of the LytR AlgR family
CKQ53_RS15790	COG3275	phosphorelay sensor kinase activity
CKQ53_RS15795	COG3081	Nucleoid-associated protein
CKQ53_RS15800	COG3082	Protein of unknown function (DUF1414)
CKQ53_RS15815	COG1278	Cold shock
CKQ53_RS15820	COG3122	Protein conserved in bacteria
CKQ53_RS15830	COG1278	Cold shock
CKQ53_RS15835	COG3136	membrane protein required for alginate biosynthesis
CKQ53_RS15840	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CKQ53_RS15845	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CKQ53_RS15850	COG0783	Belongs to the Dps family
CKQ53_RS15855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CKQ53_RS15860	COG0765	amino acid transport
CKQ53_RS15865	COG1126	abc transporter atp-binding protein
CKQ53_RS15870	COG0671	phosphoesterase, PA-phosphatase related
CKQ53_RS15880	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CKQ53_RS15900	COG1472	Belongs to the glycosyl hydrolase 3 family
CKQ53_RS15915	COG1349	DNA-binding transcription factor activity
CKQ53_RS15925	COG1686	Belongs to the peptidase S11 family
CKQ53_RS15930	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CKQ53_RS15940	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CKQ53_RS15955	COG0513	Belongs to the DEAD box helicase family
CKQ53_RS15965	COG0392	lysyltransferase activity
CKQ53_RS15970	COG0670	Belongs to the BI1 family
CKQ53_RS15975	COG0314	molybdopterin synthase activity
CKQ53_RS15980	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CKQ53_RS15990	COG0521	Mo-molybdopterin cofactor biosynthetic process
CKQ53_RS15995	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CKQ53_RS16000	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CKQ53_RS16010	COG1116	anion transmembrane transporter activity
CKQ53_RS16015	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CKQ53_RS16020	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CKQ53_RS16025	COG0604	alcohol dehydrogenase
CKQ53_RS16040	COG0318	PFAM AMP-dependent synthetase and ligase
CKQ53_RS16050	COG0556	nucleotide-excision repair
CKQ53_RS16060	COG2226	methyltransferase
CKQ53_RS16065	COG0156	8-amino-7-oxononanoate synthase activity
CKQ53_RS16070	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CKQ53_RS16080	COG1380	Effector of murein hydrolase LrgA
CKQ53_RS16085	COG1346	cytolysis
CKQ53_RS16090	COG0295	cytidine deaminase activity
CKQ53_RS16095	COG0281	malic enzyme
CKQ53_RS16100	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CKQ53_RS16105	COG0601	transmembrane transport
CKQ53_RS16110	COG0747	negative chemotaxis
CKQ53_RS16115	COG4172	Belongs to the ABC transporter superfamily
CKQ53_RS16120	COG0303	'Molybdopterin
CKQ53_RS16125	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CKQ53_RS16145	COG0401	homolog of Blt101
CKQ53_RS16175	COG4172	Belongs to the ABC transporter superfamily
CKQ53_RS16180	COG0405	Gamma-glutamyltransferase
CKQ53_RS16185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CKQ53_RS16195	COG0747	negative chemotaxis
CKQ53_RS16200	COG2186	Transcriptional regulator
CKQ53_RS16210	COG1984	allophanate hydrolase subunit 2
CKQ53_RS16245	COG0028	Belongs to the TPP enzyme family
CKQ53_RS16330	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CKQ53_RS16340	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CKQ53_RS16345	COG0322	excinuclease ABC activity
CKQ53_RS16350	COG2197	response regulator
CKQ53_RS16365	COG1113	amino acid transport
CKQ53_RS16390	COG0546	phosphoglycolate phosphatase activity
CKQ53_RS16395	COG2313	pseudouridylate synthase activity
CKQ53_RS16415	COG0583	DNA-binding transcription factor activity
CKQ53_RS16425	COG1309	transcriptional regulator
CKQ53_RS16430	COG0251	oxidation-reduction process
CKQ53_RS16445	COG1902	pentaerythritol trinitrate reductase activity
CKQ53_RS16450	COG1349	DNA-binding transcription factor activity
CKQ53_RS16455	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CKQ53_RS16465	COG1028	Short-chain dehydrogenase reductase Sdr
CKQ53_RS16490	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CKQ53_RS16505	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CKQ53_RS16520	COG0402	S-adenosylhomocysteine deaminase activity
CKQ53_RS16525	COG0493	'glutamate synthase
CKQ53_RS16525	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CKQ53_RS16530	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CKQ53_RS16530	COG3608	succinylglutamate desuccinylase aspartoacylase
CKQ53_RS16540	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CKQ53_RS16545	COG3829	transcription factor binding
CKQ53_RS16550	COG2068	MobA-Related Protein
CKQ53_RS16570	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CKQ53_RS16575	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CKQ53_RS16580	COG1116	anion transmembrane transporter activity
CKQ53_RS16590	COG0837	glucose binding
CKQ53_RS16590	COG1737	Transcriptional regulator
CKQ53_RS16605	COG2814	Major facilitator Superfamily
CKQ53_RS16615	COG0596	Alpha beta hydrolase
CKQ53_RS16620	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CKQ53_RS16625	COG0625	glutathione transferase activity
CKQ53_RS16635	COG2130	NADP-dependent
CKQ53_RS16640	COG1902	pentaerythritol trinitrate reductase activity
CKQ53_RS16650	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CKQ53_RS16685	COG1064	alcohol dehydrogenase
CKQ53_RS16690	COG2194	sulfuric ester hydrolase activity
CKQ53_RS16715	COG1215	transferase activity, transferring glycosyl groups
CKQ53_RS16730	COG3118	belongs to the thioredoxin family
CKQ53_RS16730	COG0457	Tetratricopeptide repeat
CKQ53_RS16735	COG2200	EAL domain
CKQ53_RS16740	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CKQ53_RS16745	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CKQ53_RS16750	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CKQ53_RS16775	COG2814	Major facilitator Superfamily
CKQ53_RS16780	COG3058	Necessary for formate dehydrogenase activity
CKQ53_RS16790	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CKQ53_RS16790	COG0519	Catalyzes the synthesis of GMP from XMP
CKQ53_RS16795	COG0488	(ABC) transporter
CKQ53_RS16800	COG0384	phenazine biosynthesis protein PhzF
CKQ53_RS16805	COG4575	ribosome binding
CKQ53_RS16810	COG1007	ATP synthesis coupled electron transport
CKQ53_RS16815	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CKQ53_RS16820	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CKQ53_RS16825	COG0713	ATP synthesis coupled electron transport
CKQ53_RS16830	COG0839	Belongs to the complex I subunit 6 family
CKQ53_RS16835	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CKQ53_RS16840	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CKQ53_RS16850	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CKQ53_RS16860	COG0649	NAD binding
CKQ53_RS16860	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CKQ53_RS16870	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CKQ53_RS16875	COG0583	DNA-binding transcription factor activity
CKQ53_RS16880	COG0436	Aminotransferase
CKQ53_RS16885	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
CKQ53_RS16890	COG0490	domain, Protein
CKQ53_RS16890	COG0471	metal ion transport
CKQ53_RS16895	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CKQ53_RS16900	COG3013	Belongs to the UPF0304 family
CKQ53_RS16905	COG3092	negative regulation of chromosome organization
CKQ53_RS16910	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CKQ53_RS16915	COG0857	belongs to the CobB CobQ family
CKQ53_RS16915	COG0280	phosphate acetyltransferase
CKQ53_RS16925	COG0622	Phosphoesterase
CKQ53_RS16930	COG1090	epimerase
CKQ53_RS16945	COG4215	(ABC) transporter
CKQ53_RS16955	COG0163	prenyltransferase activity
CKQ53_RS16960	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CKQ53_RS16965	COG1286	toxin biosynthetic process
CKQ53_RS16970	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
CKQ53_RS16975	COG0285	dihydrofolate synthase activity
CKQ53_RS16980	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CKQ53_RS16985	COG0586	Pfam SNARE associated Golgi protein
CKQ53_RS16990	COG0101	tRNA pseudouridine synthase activity
CKQ53_RS16995	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CKQ53_RS17000	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CKQ53_RS17010	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CKQ53_RS17015	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CKQ53_RS17015	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CKQ53_RS17040	COG3101	peptidyl-lysine hydroxylation
CKQ53_RS17045	COG0730	response to heat
CKQ53_RS17050	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
CKQ53_RS17055	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CKQ53_RS17060	COG2890	protein-(glutamine-N5) methyltransferase activity
CKQ53_RS17065	COG2840	Smr protein MutS2
CKQ53_RS17070	COG2062	phosphohistidine phosphatase, SixA
CKQ53_RS17075	COG3691	Protein conserved in bacteria
CKQ53_RS17085	COG0579	oxidoreductase
CKQ53_RS17095	COG2116	formate transmembrane transporter activity
CKQ53_RS17130	COG2999	glutathione oxidoreductase activity
CKQ53_RS17135	COG0583	DNA-binding transcription factor activity
CKQ53_RS17140	COG2259	Doxx family
CKQ53_RS17145	COG0400	carboxylic ester hydrolase activity
CKQ53_RS17150	COG4592	Periplasmic binding protein
CKQ53_RS17160	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CKQ53_RS17165	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CKQ53_RS17170	COG1120	ATPase activity
CKQ53_RS17185	COG2382	esterase
CKQ53_RS17190	COG4774	siderophore transport
CKQ53_RS17200	COG1169	isochorismate synthase
CKQ53_RS17205	COG1021	2,3-dihydroxybenzoate-AMP ligase
CKQ53_RS17210	COG3433	isochorismatase activity
CKQ53_RS17210	COG1535	isochorismatase
CKQ53_RS17215	COG1028	Short-chain dehydrogenase reductase Sdr
CKQ53_RS17230	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CKQ53_RS17285	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CKQ53_RS17300	COG3266	domain, Protein
CKQ53_RS17310	COG0436	Aminotransferase
CKQ53_RS17320	COG4948	Mandelate Racemase Muconate Lactonizing
CKQ53_RS17325	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CKQ53_RS17335	COG3264	Mechanosensitive ion channel
CKQ53_RS17335	COG1196	nuclear chromosome segregation
CKQ53_RS17355	COG2963	transposase activity
CKQ53_RS17365	COG2246	polysaccharide biosynthetic process
CKQ53_RS17385	COG0840	transmembrane signaling receptor activity
CKQ53_RS17390	COG1522	sequence-specific DNA binding
CKQ53_RS17400	COG0583	DNA-binding transcription factor activity
CKQ53_RS17410	COG4608	Belongs to the ABC transporter superfamily
CKQ53_RS17415	COG0444	Belongs to the ABC transporter superfamily
CKQ53_RS17420	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CKQ53_RS17425	COG0601	transmembrane transport
CKQ53_RS17435	COG1279	arginine transmembrane transporter activity
CKQ53_RS17445	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CKQ53_RS17450	COG2501	S4 domain
CKQ53_RS17465	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CKQ53_RS17470	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CKQ53_RS17475	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CKQ53_RS17480	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CKQ53_RS17485	COG0814	amino acid
CKQ53_RS17505	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CKQ53_RS17510	COG0589	response to stress
CKQ53_RS17535	COG0670	Belongs to the BI1 family
CKQ53_RS17540	COG2920	part of a sulfur-relay system
CKQ53_RS17545	COG1254	Belongs to the acylphosphatase family
CKQ53_RS17550	COG3785	DNA binding
CKQ53_RS17555	COG1832	CoA-binding protein
CKQ53_RS17565	COG1803	Methylglyoxal synthase
CKQ53_RS17570	COG0210	DNA helicase
CKQ53_RS17575	COG3304	Inner membrane component domain
CKQ53_RS17580	COG1289	transmembrane transporter activity
CKQ53_RS17585	COG3070	regulator of competence-specific genes
CKQ53_RS17590	COG5404	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division
CKQ53_RS17595	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CKQ53_RS17595	COG2885	chlorophyll binding
CKQ53_RS17600	COG0667	Aldo Keto reductase
CKQ53_RS17605	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CKQ53_RS17610	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CKQ53_RS17615	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CKQ53_RS17620	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CKQ53_RS17625	COG0435	Glutathione S-transferase
CKQ53_RS17630	COG0826	peptidase U32
CKQ53_RS17635	COG1597	lipid kinase activity
CKQ53_RS17640	COG3223	Belongs to the PsiE family
CKQ53_RS17645	COG0351	phosphomethylpyrimidine kinase
CKQ53_RS17650	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CKQ53_RS17655	COG3722	fumarate hydratase activity
CKQ53_RS17660	COG0246	Mannitol dehydrogenase
CKQ53_RS17665	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CKQ53_RS17665	COG2213	PTS system mannitol-specific
CKQ53_RS17690	COG3501	Rhs element vgr protein
CKQ53_RS17700	COG1566	PFAM secretion protein HlyD family protein
CKQ53_RS17705	COG2814	Major facilitator Superfamily
CKQ53_RS17730	COG0671	phosphoesterase, PA-phosphatase related
CKQ53_RS17730	COG2453	phosphatase
CKQ53_RS17735	COG2267	carboxylic ester hydrolase activity
CKQ53_RS17740	COG4589	Belongs to the CDS family
CKQ53_RS17745	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CKQ53_RS17760	COG2801	Transposase and inactivated derivatives
CKQ53_RS17770	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CKQ53_RS17770	COG0519	Catalyzes the synthesis of GMP from XMP
CKQ53_RS17775	COG0516	GMP reductase activity
CKQ53_RS17775	COG0517	IMP dehydrogenase activity
CKQ53_RS17780	COG1570	exodeoxyribonuclease VII activity
CKQ53_RS17795	COG1645	bacterial-type flagellum-dependent swarming motility
CKQ53_RS17800	COG1160	GTP binding
CKQ53_RS17805	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CKQ53_RS17810	COG2976	Protein conserved in bacteria
CKQ53_RS17815	COG0124	histidyl-tRNA synthetase
CKQ53_RS17820	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CKQ53_RS17825	COG1426	Protein conserved in bacteria
CKQ53_RS17835	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CKQ53_RS17840	COG0105	UTP biosynthetic process
CKQ53_RS17845	COG2897	thiosulfate sulfurtransferase activity
CKQ53_RS17855	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CKQ53_RS17865	COG1959	2 iron, 2 sulfur cluster binding
CKQ53_RS17870	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CKQ53_RS17875	COG0483	inositol monophosphate 1-phosphatase activity
CKQ53_RS17880	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CKQ53_RS17885	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CKQ53_RS17895	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CKQ53_RS17900	COG3683	transport system, periplasmic component
CKQ53_RS17905	COG2814	Major facilitator Superfamily
CKQ53_RS17910	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CKQ53_RS17920	COG3866	Pectate lyase
CKQ53_RS17930	COG0347	Belongs to the P(II) protein family
CKQ53_RS17935	COG2204	response regulator
CKQ53_RS17940	COG3170	Tfp pilus assembly protein FimV
CKQ53_RS17945	COG2205	protein histidine kinase activity
CKQ53_RS17950	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CKQ53_RS17950	COG0047	phosphoribosylformylglycinamidine synthase activity
CKQ53_RS17955	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CKQ53_RS17965	COG0560	Phosphoserine phosphatase
CKQ53_RS17970	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CKQ53_RS17980	COG5001	Diguanylate cyclase
CKQ53_RS17980	COG3300	MHYT domain
CKQ53_RS18015	COG2200	EAL domain
CKQ53_RS18020	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CKQ53_RS18030	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CKQ53_RS18050	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CKQ53_RS18055	COG0571	ribonuclease III activity
CKQ53_RS18070	COG3026	antisigma factor binding
CKQ53_RS18085	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CKQ53_RS18090	COG0513	Belongs to the DEAD box helicase family
CKQ53_RS18095	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
CKQ53_RS18100	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CKQ53_RS18115	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CKQ53_RS18285	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CKQ53_RS18325	COG3267	Type II secretory pathway component ExeA
CKQ53_RS18325	COG3409	Peptidoglycan-binding domain 1 protein