locus-tag	class	description
CNR27_RS00015	COG3483	tryptophan 2,3-dioxygenase activity
CNR27_RS00020	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CNR27_RS00030	COG0508	dehydrogenase complex catalyzes the overall conversion of
CNR27_RS00060	COG0180	Tryptophanyl-tRNA synthetase
CNR27_RS00065	COG3237	CsbD-like
CNR27_RS00090	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CNR27_RS00095	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CNR27_RS00095	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CNR27_RS00100	COG3228	Belongs to the MtfA family
CNR27_RS00120	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CNR27_RS00140	COG2264	protein methyltransferase activity
CNR27_RS00150	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CNR27_RS00155	COG0138	bifunctional purine biosynthesis protein purh
CNR27_RS00165	COG1115	amino acid carrier protein
CNR27_RS00170	COG0151	Belongs to the GarS family
CNR27_RS00175	COG1607	acyl-coa hydrolase
CNR27_RS00235	COG1051	belongs to the nudix hydrolase family
CNR27_RS00300	COG1505	serine-type exopeptidase activity
CNR27_RS00325	COG3273	potassium ion transport
CNR27_RS00325	COG0471	metal ion transport
CNR27_RS00340	COG0181	hydroxymethylbilane synthase activity
CNR27_RS00350	COG3275	phosphorelay sensor kinase activity
CNR27_RS00360	COG2943	transferase activity, transferring hexosyl groups
CNR27_RS00365	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
CNR27_RS00400	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CNR27_RS00420	COG0577	efflux transmembrane transporter activity
CNR27_RS00420	COG1136	(ABC) transporter
CNR27_RS00425	COG0577	efflux transmembrane transporter activity
CNR27_RS00425	COG1136	(ABC) transporter
CNR27_RS00435	COG4191	Histidine kinase
CNR27_RS00440	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CNR27_RS00455	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CNR27_RS00460	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CNR27_RS00465	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CNR27_RS00470	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CNR27_RS00480	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CNR27_RS00490	COG0356	it plays a direct role in the translocation of protons across the membrane
CNR27_RS00505	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CNR27_RS00510	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CNR27_RS00510	COG3153	acetyltransferase
CNR27_RS00515	COG0508	dehydrogenase complex catalyzes the overall conversion of
CNR27_RS00520	COG3047	cAMP biosynthetic process
CNR27_RS00530	COG0697	spore germination
CNR27_RS00535	COG1064	alcohol dehydrogenase
CNR27_RS00540	COG1666	GTP binding
CNR27_RS00555	COG0640	Transcriptional regulator
CNR27_RS00565	COG1187	pseudouridine synthase activity
CNR27_RS00570	COG2813	Specifically methylates the guanine in position
CNR27_RS00585	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CNR27_RS00590	COG1129	ABC transporter
CNR27_RS00590	COG0842	Transport permease protein
CNR27_RS00595	COG0842	Transport permease protein
CNR27_RS00600	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CNR27_RS00605	COG4181	ATPase activity
CNR27_RS00615	COG0739	heme binding
CNR27_RS00620	COG1376	ErfK ybiS ycfS ynhG family protein
CNR27_RS00645	COG3795	YCII-related domain
CNR27_RS00655	COG0714	Associated with various cellular activities
CNR27_RS00680	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CNR27_RS00690	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CNR27_RS00700	COG0438	transferase activity, transferring glycosyl groups
CNR27_RS00705	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CNR27_RS00705	COG2755	lipolytic protein G-D-S-L family
CNR27_RS00720	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CNR27_RS00750	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CNR27_RS00755	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CNR27_RS00785	COG1596	polysaccharide export
CNR27_RS00790	COG4464	protein tyrosine phosphatase activity
CNR27_RS00795	COG0582	viral genome integration into host DNA
CNR27_RS00835	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CNR27_RS00850	COG0708	Exodeoxyribonuclease III
CNR27_RS00865	COG0357	Ribosomal RNA small subunit methyltransferase G
CNR27_RS00870	COG1192	Involved in chromosome partitioning
CNR27_RS00900	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CNR27_RS00930	COG3964	amidohydrolase
CNR27_RS00935	COG0402	S-adenosylhomocysteine deaminase activity
CNR27_RS00965	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
CNR27_RS00980	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CNR27_RS01025	COG0840	transmembrane signaling receptor activity
CNR27_RS01035	COG0083	homoserine kinase activity
CNR27_RS01040	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CNR27_RS01045	COG2823	Periplasmic or secreted lipoprotein
CNR27_RS01095	COG0473	3-isopropylmalate dehydrogenase activity
CNR27_RS01100	COG0129	dihydroxy-acid dehydratase activity
CNR27_RS01120	COG2801	Transposase and inactivated derivatives
CNR27_RS01195	COG1228	amidohydrolase
CNR27_RS01225	COG1309	transcriptional regulator
CNR27_RS01230	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CNR27_RS01235	COG1538	Outer membrane efflux protein
CNR27_RS01240	COG1519	Transferase
CNR27_RS01245	COG1560	Kdo2-lipid A biosynthetic process
CNR27_RS01265	COG1741	Belongs to the pirin family
CNR27_RS01285	COG0546	phosphoglycolate phosphatase activity
CNR27_RS01295	COG0025	NhaP-type Na H and K H
CNR27_RS01325	COG1573	uracil-dna glycosylase
CNR27_RS01335	COG2010	Cytochrome c
CNR27_RS01335	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CNR27_RS01340	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CNR27_RS01365	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CNR27_RS01375	COG0667	Aldo Keto reductase
CNR27_RS01410	COG2814	Major facilitator Superfamily
CNR27_RS01445	COG1199	ATP-dependent helicase activity
CNR27_RS01450	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CNR27_RS01510	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CNR27_RS01525	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CNR27_RS01545	COG0671	phosphoesterase, PA-phosphatase related
CNR27_RS01555	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CNR27_RS01570	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CNR27_RS01575	COG1435	thymidine kinase activity
CNR27_RS01585	COG0210	DNA helicase
CNR27_RS01590	COG3132	Protein of unknown function, DUF480
CNR27_RS01595	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
CNR27_RS01670	COG4669	(LipO)protein
CNR27_RS01690	COG4789	Type iii secretion
CNR27_RS01705	COG4566	intracellular signal transduction
CNR27_RS01710	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CNR27_RS01725	COG4794	Type iii secretion
CNR27_RS01730	COG4791	protein targeting
CNR27_RS01740	COG4792	protein secretion
CNR27_RS01760	COG2937	Belongs to the GPAT DAPAT family
CNR27_RS01770	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CNR27_RS01775	COG0037	tRNA processing
CNR27_RS01790	COG0596	Alpha beta hydrolase
CNR27_RS01795	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CNR27_RS01815	COG0805	protein transport
CNR27_RS01830	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CNR27_RS01830	COG0519	Catalyzes the synthesis of GMP from XMP
CNR27_RS01835	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CNR27_RS01840	COG0752	glycyl-tRNA synthetase alpha subunit
CNR27_RS01850	COG0729	surface antigen
CNR27_RS01860	COG1446	asparaginase
CNR27_RS01885	COG2204	response regulator
CNR27_RS01895	COG3685	Protein conserved in bacteria
CNR27_RS01910	COG2183	response to ionizing radiation
CNR27_RS01915	COG3546	catalase activity
CNR27_RS01920	COG1335	isochorismatase
CNR27_RS01945	COG3279	Response regulator of the LytR AlgR family
CNR27_RS01955	COG3685	Protein conserved in bacteria
CNR27_RS01980	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CNR27_RS02020	COG0697	spore germination
CNR27_RS02025	COG0156	8-amino-7-oxononanoate synthase activity
CNR27_RS02035	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CNR27_RS02040	COG1040	competence protein
CNR27_RS02050	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CNR27_RS02055	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CNR27_RS02065	COG0793	Belongs to the peptidase S41A family
CNR27_RS02070	COG2852	Protein conserved in bacteria
CNR27_RS02075	COG4942	peptidase
CNR27_RS02080	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CNR27_RS02120	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CNR27_RS02125	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
CNR27_RS02160	COG3179	chitinase
CNR27_RS02175	COG0405	Gamma-glutamyltransferase
CNR27_RS02200	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CNR27_RS02220	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CNR27_RS02245	COG1881	PFAM PEBP family protein
CNR27_RS02255	COG2764	glyoxalase bleomycin resistance protein dioxygenase
CNR27_RS02265	COG4941	Belongs to the sigma-70 factor family
CNR27_RS02285	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CNR27_RS02290	COG0318	PFAM AMP-dependent synthetase and ligase
CNR27_RS02300	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CNR27_RS02305	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CNR27_RS02320	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CNR27_RS02330	COG0612	Peptidase, M16
CNR27_RS02345	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CNR27_RS02345	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CNR27_RS02365	COG3023	N-Acetylmuramoyl-L-alanine amidase
CNR27_RS02370	COG0004	ammonium transporteR
CNR27_RS02375	COG0347	Belongs to the P(II) protein family
CNR27_RS02385	COG0174	glutamine synthetase
CNR27_RS02390	COG1522	sequence-specific DNA binding
CNR27_RS02395	COG3186	Phenylalanine-4-hydroxylase
CNR27_RS02400	COG4772	TonB-dependent receptor
CNR27_RS02435	COG0784	Response regulator, receiver
CNR27_RS02450	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CNR27_RS02490	COG0501	Belongs to the peptidase M48B family
CNR27_RS02495	COG0187	DNA topoisomerase II activity
CNR27_RS02500	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CNR27_RS02515	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CNR27_RS02520	COG0594	ribonuclease P activity
CNR27_RS02525	COG0706	membrane insertase activity
CNR27_RS02535	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
CNR27_RS02545	COG4555	ABC transporter
CNR27_RS02570	COG0543	2 iron, 2 sulfur cluster binding
CNR27_RS02575	COG1131	(ABC) transporter
CNR27_RS02580	COG0842	Transport permease protein
CNR27_RS02585	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CNR27_RS02615	COG0339	signal peptide processing
CNR27_RS02665	COG4206	TonB-dependent receptor
CNR27_RS02670	COG0326	Molecular chaperone. Has ATPase activity
CNR27_RS02685	COG1538	Outer membrane efflux protein
CNR27_RS02700	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CNR27_RS02715	COG0583	DNA-binding transcription factor activity
CNR27_RS02720	COG2130	NADP-dependent
CNR27_RS02725	COG0667	Aldo Keto reductase
CNR27_RS02735	COG1187	pseudouridine synthase activity
CNR27_RS02750	COG1643	Atp-dependent helicase
CNR27_RS02755	COG0084	hydrolase, TatD family'
CNR27_RS02760	COG1968	undecaprenyl-diphosphatase activity
CNR27_RS02780	COG0708	Exodeoxyribonuclease III
CNR27_RS02785	COG2211	Major facilitator Superfamily
CNR27_RS02795	COG0739	heme binding
CNR27_RS02800	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CNR27_RS02815	COG1388	LysM domain
CNR27_RS02825	COG2951	lytic endotransglycosylase activity
CNR27_RS02830	COG3012	SEC-C Motif Domain Protein
CNR27_RS02860	COG0668	transmembrane transport
CNR27_RS02865	COG1752	Esterase of the alpha-beta hydrolase superfamily
CNR27_RS02900	COG0583	DNA-binding transcription factor activity
CNR27_RS02905	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CNR27_RS02920	COG0606	chelatase, subunit chli
CNR27_RS02940	COG1166	arginine decarboxylase activity
CNR27_RS02950	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CNR27_RS02955	COG4221	oxidoreductase activity
CNR27_RS02960	COG0653	protein targeting
CNR27_RS02980	COG0018	arginyl-trna synthetase
CNR27_RS02990	COG0302	gtp cyclohydrolase
CNR27_RS03010	COG0754	glutathionylspermidine amidase activity
CNR27_RS03015	COG0513	Belongs to the DEAD box helicase family
CNR27_RS03025	COG0583	DNA-binding transcription factor activity
CNR27_RS03065	COG1136	(ABC) transporter
CNR27_RS03100	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CNR27_RS03120	COG2211	Major facilitator Superfamily
CNR27_RS03125	COG3459	Glycosyltransferase 36 associated
CNR27_RS03130	COG3265	gluconokinase activity
CNR27_RS03155	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CNR27_RS03160	COG1074	ATP-dependent DNA helicase activity
CNR27_RS03165	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CNR27_RS03170	COG1368	sulfuric ester hydrolase activity
CNR27_RS03180	COG1127	ABC transporter
CNR27_RS03185	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CNR27_RS03190	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CNR27_RS03205	COG2853	Lipoprotein
CNR27_RS03210	COG0386	Belongs to the glutathione peroxidase family
CNR27_RS03215	COG1322	Protein conserved in bacteria
CNR27_RS03230	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CNR27_RS03240	COG3852	Histidine kinase
CNR27_RS03245	COG2204	response regulator
CNR27_RS03255	COG2032	superoxide dismutase activity
CNR27_RS03290	COG0727	PFAM Uncharacterised protein family (UPF0153)
CNR27_RS03295	COG0596	Alpha beta hydrolase
CNR27_RS03310	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CNR27_RS03320	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CNR27_RS03325	COG0583	DNA-binding transcription factor activity
CNR27_RS03335	COG4771	TonB-dependent receptor
CNR27_RS03340	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CNR27_RS03345	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CNR27_RS03360	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CNR27_RS03375	COG3588	fructose-bisphosphate aldolase
CNR27_RS03380	COG3713	MltA-interacting MipA family protein
CNR27_RS03385	COG1321	iron dependent repressor
CNR27_RS03405	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CNR27_RS03410	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CNR27_RS03420	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CNR27_RS03470	COG1565	acr, cog1565
CNR27_RS03470	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CNR27_RS03480	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
CNR27_RS03505	COG1612	heme a metabolic process
CNR27_RS03510	COG0109	protoheme IX farnesyltransferase activity
CNR27_RS03520	COG0358	DNA primase activity
CNR27_RS03525	COG1295	ribonuclease BN
CNR27_RS03530	COG0456	acetyltransferase
CNR27_RS03530	COG0454	-acetyltransferase
CNR27_RS03545	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CNR27_RS03550	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CNR27_RS03555	COG0668	transmembrane transport
CNR27_RS03560	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CNR27_RS03585	COG3178	'Phosphotransferase
CNR27_RS03605	COG0617	tRNA 3'-terminal CCA addition
CNR27_RS03625	COG1473	amidohydrolase
CNR27_RS03635	COG4206	TonB-dependent receptor
CNR27_RS03660	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CNR27_RS03680	COG0625	glutathione transferase activity
CNR27_RS03695	COG0708	Exodeoxyribonuclease III
CNR27_RS03710	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CNR27_RS03720	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CNR27_RS03735	COG2205	protein histidine kinase activity
CNR27_RS03745	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CNR27_RS03770	COG0436	Aminotransferase
CNR27_RS03785	COG0280	phosphate acetyltransferase
CNR27_RS03785	COG0281	malic enzyme
CNR27_RS03790	COG2204	response regulator
CNR27_RS03795	COG0745	RESPONSE REGULATOR receiver
CNR27_RS03800	COG4251	negative regulation of phosphorylation
CNR27_RS03850	COG1063	alcohol dehydrogenase
CNR27_RS03880	COG0667	Aldo Keto reductase
CNR27_RS03890	COG1309	transcriptional regulator
CNR27_RS03900	COG0642	Histidine kinase
CNR27_RS03935	COG1366	Belongs to the anti-sigma-factor antagonist family
CNR27_RS03940	COG1366	Belongs to the anti-sigma-factor antagonist family
CNR27_RS03945	COG2172	sigma factor antagonist activity
CNR27_RS03955	COG2205	protein histidine kinase activity
CNR27_RS03955	COG0784	Response regulator, receiver
CNR27_RS03995	COG3214	Protein conserved in bacteria
CNR27_RS04005	COG1028	Short-chain dehydrogenase reductase Sdr
CNR27_RS04025	COG1404	Belongs to the peptidase S8 family
CNR27_RS04060	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CNR27_RS04085	COG1028	Short-chain dehydrogenase reductase Sdr
CNR27_RS04095	COG0579	oxidoreductase
CNR27_RS04110	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CNR27_RS04145	COG0625	glutathione transferase activity
CNR27_RS04150	COG1472	Belongs to the glycosyl hydrolase 3 family
CNR27_RS04155	COG1609	Transcriptional regulator
CNR27_RS04190	COG0210	DNA helicase
CNR27_RS04210	COG0673	inositol 2-dehydrogenase activity
CNR27_RS04225	COG0564	pseudouridine synthase activity
CNR27_RS04230	COG0408	coproporphyrinogen oxidase activity
CNR27_RS04245	COG1271	oxidase subunit
CNR27_RS04250	COG1294	oxidase, subunit
CNR27_RS04255	COG3100	YcgL domain-containing protein
CNR27_RS04270	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CNR27_RS04275	COG3118	belongs to the thioredoxin family
CNR27_RS04285	COG2884	Cell division ATP-binding protein ftsE
CNR27_RS04290	COG2177	Part of the ABC transporter FtsEX involved in
CNR27_RS04295	COG2201	protein-glutamate methylesterase activity
CNR27_RS04300	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CNR27_RS04320	COG0720	synthase
CNR27_RS04325	COG2832	Protein of unknown function (DUF454)
CNR27_RS04345	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CNR27_RS04370	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CNR27_RS04375	COG5342	invasion associated locus B
CNR27_RS04390	COG0659	secondary active sulfate transmembrane transporter activity
CNR27_RS04400	COG1253	flavin adenine dinucleotide binding
CNR27_RS04405	COG2226	methyltransferase
CNR27_RS04425	COG0308	aminopeptidase N
CNR27_RS04440	COG0534	Mate efflux family protein
CNR27_RS04470	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CNR27_RS04475	COG1077	Cell shape determining protein MreB Mrl
CNR27_RS04480	COG1792	Involved in formation and maintenance of cell shape
CNR27_RS04490	COG0768	penicillin binding
CNR27_RS04495	COG0772	Belongs to the SEDS family
CNR27_RS04500	COG2951	lytic endotransglycosylase activity
CNR27_RS04510	COG1686	Belongs to the peptidase S11 family
CNR27_RS04515	COG2921	Belongs to the UPF0250 family
CNR27_RS04530	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CNR27_RS04540	COG0697	spore germination
CNR27_RS04565	COG0577	efflux transmembrane transporter activity
CNR27_RS04570	COG1136	(ABC) transporter
CNR27_RS04580	COG1131	(ABC) transporter
CNR27_RS04585	COG0842	Transport permease protein
CNR27_RS04590	COG1228	amidohydrolase
CNR27_RS04595	COG4585	Histidine kinase
CNR27_RS04600	COG2197	response regulator
CNR27_RS04605	COG5383	Protein conserved in bacteria
CNR27_RS04615	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CNR27_RS04625	COG0628	permease
CNR27_RS04645	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CNR27_RS04665	COG1960	acyl-CoA dehydrogenase activity
CNR27_RS04670	COG1960	acyl-CoA dehydrogenase activity
CNR27_RS04675	COG1764	response to oxidative stress
CNR27_RS04695	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CNR27_RS04720	COG1187	pseudouridine synthase activity
CNR27_RS04740	COG3920	Histidine kinase
CNR27_RS04740	COG2202	Pas domain
CNR27_RS04780	COG0702	epimerase
CNR27_RS04795	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CNR27_RS04800	COG2094	Belongs to the DNA glycosylase MPG family
CNR27_RS04840	COG2133	pyrroloquinoline quinone binding
CNR27_RS04875	COG0439	Biotin carboxylase
CNR27_RS04880	COG0511	ligase activity, forming carbon-carbon bonds
CNR27_RS04885	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CNR27_RS04890	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CNR27_RS04905	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CNR27_RS04910	COG0459	protein refolding
CNR27_RS04920	COG2081	HI0933 family
CNR27_RS04935	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CNR27_RS04940	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CNR27_RS04945	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CNR27_RS04950	COG0428	transporter
CNR27_RS04960	COG2927	DNA polymerase III (CHI subunit)
CNR27_RS04965	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CNR27_RS04975	COG0795	lipopolysaccharide-transporting ATPase activity
CNR27_RS04985	COG4974	Belongs to the 'phage' integrase family
CNR27_RS04990	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CNR27_RS04995	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CNR27_RS04995	COG0047	phosphoribosylformylglycinamidine synthase activity
CNR27_RS05045	COG5295	Hep Hag repeat protein
CNR27_RS05050	COG1404	Belongs to the peptidase S8 family
CNR27_RS05065	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CNR27_RS05075	COG1459	type II secretion system
CNR27_RS05085	COG2165	general secretion pathway protein
CNR27_RS05090	COG4970	Tfp pilus assembly protein FimT
CNR27_RS05095	COG2165	general secretion pathway protein
CNR27_RS05100	COG4795	General secretion pathway protein
CNR27_RS05105	COG3156	type II secretion system protein K
CNR27_RS05110	COG3166	PFAM Fimbrial assembly family protein
CNR27_RS05125	COG1450	Type ii and iii secretion system protein
CNR27_RS05140	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CNR27_RS05150	COG0284	orotidine-5'-phosphate decarboxylase activity
CNR27_RS05155	COG0024	Methionine aminopeptidase
CNR27_RS05160	COG0488	(ABC) transporter
CNR27_RS05165	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CNR27_RS05175	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CNR27_RS05175	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CNR27_RS05190	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CNR27_RS05195	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CNR27_RS05235	COG0275	rRNA processing
CNR27_RS05240	COG3116	cell division
CNR27_RS05250	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CNR27_RS05255	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CNR27_RS05270	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CNR27_RS05275	COG1181	Belongs to the D-alanine--D-alanine ligase family
CNR27_RS05280	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CNR27_RS05305	COG0739	heme binding
CNR27_RS05310	COG0653	protein targeting
CNR27_RS05315	COG0352	thiamine-phosphate diphosphorylase activity
CNR27_RS05325	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CNR27_RS05340	COG4969	Belongs to the N-Me-Phe pilin family
CNR27_RS05360	COG0045	succinate-CoA ligase (ADP-forming) activity
CNR27_RS05370	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CNR27_RS05370	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CNR27_RS05375	COG1490	D-aminoacyl-tRNA deacylase activity
CNR27_RS05380	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CNR27_RS05395	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CNR27_RS05425	COG0006	proline dipeptidase activity
CNR27_RS05430	COG0006	proline dipeptidase activity
CNR27_RS05445	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CNR27_RS05455	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CNR27_RS05460	COG1561	YicC-like family, N-terminal region
CNR27_RS05465	COG0194	GDP metabolic process
CNR27_RS05470	COG1758	RNA polymerase activity
CNR27_RS05475	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CNR27_RS05495	COG0254	rRNA binding
CNR27_RS05545	COG0714	Associated with various cellular activities
CNR27_RS05575	COG0783	Belongs to the Dps family
CNR27_RS05580	COG1643	Atp-dependent helicase
CNR27_RS05595	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CNR27_RS05610	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CNR27_RS05620	COG1199	ATP-dependent helicase activity
CNR27_RS05630	COG0681	Belongs to the peptidase S26 family
CNR27_RS05640	COG0189	ligase activity
CNR27_RS05660	COG0840	transmembrane signaling receptor activity
CNR27_RS05665	COG2198	Histidine kinase
CNR27_RS05665	COG0643	Histidine kinase
CNR27_RS05665	COG0784	Response regulator, receiver
CNR27_RS05680	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CNR27_RS05690	COG0494	nUDIX hydrolase
CNR27_RS05695	COG1218	3'(2'),5'-bisphosphate nucleotidase
CNR27_RS05700	COG3956	TIGRFAM MazG family protein
CNR27_RS05725	COG0642	Histidine kinase
CNR27_RS05730	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CNR27_RS05740	COG1136	(ABC) transporter
CNR27_RS05740	COG0577	efflux transmembrane transporter activity
CNR27_RS05765	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CNR27_RS05770	COG0861	Integral membrane protein TerC family
CNR27_RS05790	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CNR27_RS05795	COG2967	ApaG domain
CNR27_RS05805	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CNR27_RS05810	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CNR27_RS05815	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CNR27_RS05830	COG2096	Adenosyltransferase
CNR27_RS05840	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CNR27_RS05845	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CNR27_RS05850	COG2354	Protein conserved in bacteria
CNR27_RS05865	COG0590	tRNA wobble adenosine to inosine editing
CNR27_RS05875	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CNR27_RS05890	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CNR27_RS05895	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CNR27_RS05900	COG0583	DNA-binding transcription factor activity
CNR27_RS05905	COG3634	alkyl hydroperoxide reductase activity
CNR27_RS05930	COG2824	Alkylphosphonate utilization operon protein PhnA
CNR27_RS05935	COG2226	methyltransferase
CNR27_RS05945	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CNR27_RS05945	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CNR27_RS05950	COG0778	Nitroreductase
CNR27_RS05990	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CNR27_RS06000	COG2151	metal-sulfur cluster biosynthetic enzyme
CNR27_RS06005	COG1404	Belongs to the peptidase S8 family
CNR27_RS06020	COG0252	asparaginase activity
CNR27_RS06035	COG1295	ribonuclease BN
CNR27_RS06040	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CNR27_RS06045	COG2326	polyphosphate kinase activity
CNR27_RS06050	COG0521	Mo-molybdopterin cofactor biosynthetic process
CNR27_RS06060	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CNR27_RS06085	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CNR27_RS06095	COG0193	aminoacyl-tRNA hydrolase activity
CNR27_RS06100	COG0012	GTP binding
CNR27_RS06120	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CNR27_RS06140	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CNR27_RS06150	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CNR27_RS06155	COG0222	ribosome binding
CNR27_RS06160	COG0085	RNA polymerase activity
CNR27_RS06165	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CNR27_RS06170	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CNR27_RS06175	COG0049	tRNA binding
CNR27_RS06180	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CNR27_RS06185	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CNR27_RS06190	COG0051	transcription antitermination factor activity, RNA binding
CNR27_RS06195	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CNR27_RS06205	COG0089	rRNA binding
CNR27_RS06210	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CNR27_RS06215	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CNR27_RS06220	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CNR27_RS06235	COG0255	Belongs to the universal ribosomal protein uL29 family
CNR27_RS06240	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CNR27_RS06245	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CNR27_RS06250	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CNR27_RS06255	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CNR27_RS06260	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CNR27_RS06265	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CNR27_RS06275	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CNR27_RS06280	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CNR27_RS06285	COG1841	ribosomal large subunit assembly
CNR27_RS06290	COG0200	Binds to the 23S rRNA
CNR27_RS06295	COG0201	protein transport
CNR27_RS06300	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CNR27_RS06310	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CNR27_RS06320	COG0203	ribosomal protein L17
CNR27_RS06330	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CNR27_RS06345	COG1217	gtp-binding protein TYPA
CNR27_RS06350	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CNR27_RS06360	COG0039	L-malate dehydrogenase activity
CNR27_RS06405	COG0625	glutathione transferase activity
CNR27_RS06415	COG1902	pentaerythritol trinitrate reductase activity
CNR27_RS06415	COG0446	pyridine nucleotide-disulphide oxidoreductase
CNR27_RS06425	COG3047	cAMP biosynthetic process
CNR27_RS06425	COG2885	chlorophyll binding
CNR27_RS06435	COG1187	pseudouridine synthase activity
CNR27_RS06440	COG0156	8-amino-7-oxononanoate synthase activity
CNR27_RS06465	COG0588	phosphoglycerate mutase activity
CNR27_RS06470	COG0285	dihydrofolate synthase activity
CNR27_RS06485	COG2833	Protein of unknown function (DUF455)
CNR27_RS06495	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CNR27_RS06500	COG1522	sequence-specific DNA binding
CNR27_RS06505	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CNR27_RS06515	COG1862	Preprotein translocase
CNR27_RS06520	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CNR27_RS06530	COG0483	inositol monophosphate 1-phosphatase activity
CNR27_RS06555	COG1253	flavin adenine dinucleotide binding
CNR27_RS06565	COG0306	phosphate transporter
CNR27_RS06585	COG3590	peptidase
CNR27_RS06590	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CNR27_RS06590	COG0475	glutathione-regulated potassium exporter activity
CNR27_RS06595	COG0513	Belongs to the DEAD box helicase family
CNR27_RS06600	COG0791	NLP P60 protein
CNR27_RS06605	COG0791	NLP P60 protein
CNR27_RS06615	COG2311	Membrane
CNR27_RS06635	COG2814	Major facilitator Superfamily
CNR27_RS06655	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CNR27_RS06660	COG0148	phosphopyruvate hydratase activity
CNR27_RS06670	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CNR27_RS06675	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CNR27_RS06690	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CNR27_RS06695	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CNR27_RS06700	COG2137	regulation of response to DNA damage stimulus
CNR27_RS06705	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CNR27_RS06710	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CNR27_RS06725	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CNR27_RS06735	COG0351	phosphomethylpyrimidine kinase
CNR27_RS06735	COG0352	thiamine-phosphate diphosphorylase activity
CNR27_RS06745	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CNR27_RS06750	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CNR27_RS06760	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CNR27_RS06770	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CNR27_RS06780	COG0617	tRNA 3'-terminal CCA addition
CNR27_RS06785	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CNR27_RS06790	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CNR27_RS06795	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CNR27_RS06800	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CNR27_RS06805	COG0166	Belongs to the GPI family
CNR27_RS06810	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CNR27_RS06815	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CNR27_RS06815	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CNR27_RS06825	COG0860	N-Acetylmuramoyl-L-alanine amidase
CNR27_RS06830	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CNR27_RS06845	COG2878	Part of a membrane complex involved in electron transport
CNR27_RS06870	COG4206	TonB-dependent receptor
CNR27_RS06875	COG0489	protein tyrosine kinase activity
CNR27_RS06880	COG0717	Belongs to the dCTP deaminase family
CNR27_RS06890	COG0412	Dienelactone hydrolase
CNR27_RS06910	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CNR27_RS06915	COG0433	COG0433 Predicted ATPase
CNR27_RS06925	COG0688	phosphatidylethanolamine metabolic process
CNR27_RS06930	COG1999	signal sequence binding
CNR27_RS06935	COG2890	protein-(glutamine-N5) methyltransferase activity
CNR27_RS06940	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CNR27_RS06945	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CNR27_RS06950	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CNR27_RS06960	COG0101	tRNA pseudouridine synthase activity
CNR27_RS06965	COG0135	phosphoribosylanthranilate isomerase activity
CNR27_RS06975	COG0133	tryptophan synthase activity
CNR27_RS06980	COG0159	tryptophan synthase activity
CNR27_RS06985	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CNR27_RS07000	COG0149	triose-phosphate isomerase activity
CNR27_RS07015	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CNR27_RS07025	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CNR27_RS07030	COG0649	NAD binding
CNR27_RS07035	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CNR27_RS07040	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CNR27_RS07050	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CNR27_RS07055	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CNR27_RS07080	COG1007	ATP synthesis coupled electron transport
CNR27_RS07090	COG0779	Required for maturation of 30S ribosomal subunits
CNR27_RS07095	COG0195	Participates in both transcription termination and antitermination
CNR27_RS07110	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CNR27_RS07115	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CNR27_RS07120	COG1185	polyribonucleotide nucleotidyltransferase activity
CNR27_RS07125	COG0367	asparagine synthase
CNR27_RS07155	COG0443	Heat shock 70 kDa protein
CNR27_RS07165	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CNR27_RS07175	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CNR27_RS07180	COG1271	oxidase subunit
CNR27_RS07185	COG1294	oxidase, subunit
CNR27_RS07215	COG0557	exoribonuclease II activity
CNR27_RS07225	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CNR27_RS07240	COG1408	metallophosphoesterase
CNR27_RS07245	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CNR27_RS07250	COG0704	Plays a role in the regulation of phosphate uptake
CNR27_RS07260	COG0581	inorganic phosphate transmembrane transporter activity
CNR27_RS07265	COG0573	inorganic phosphate transmembrane transporter activity
CNR27_RS07295	COG0753	catalase activity
CNR27_RS07305	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CNR27_RS07315	COG1024	Enoyl-CoA hydratase
CNR27_RS07335	COG1024	Enoyl-CoA hydratase
CNR27_RS07345	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CNR27_RS07350	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CNR27_RS07355	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CNR27_RS07375	COG0196	riboflavin kinase activity
CNR27_RS07390	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CNR27_RS07415	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CNR27_RS07420	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CNR27_RS07435	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CNR27_RS07440	COG0336	Belongs to the RNA methyltransferase TrmD family
CNR27_RS07470	COG0492	ferredoxin-NADP+ reductase activity
CNR27_RS07485	COG0531	amino acid
CNR27_RS07500	COG0531	amino acid
CNR27_RS07505	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CNR27_RS07515	COG1546	Belongs to the CinA family
CNR27_RS07520	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CNR27_RS07530	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CNR27_RS07540	COG1595	DNA-templated transcription, initiation
CNR27_RS07550	COG1946	Acyl-CoA thioesterase
CNR27_RS07575	COG1741	Belongs to the pirin family
CNR27_RS07585	COG1741	Belongs to the pirin family
CNR27_RS07605	COG0811	peptide transport
CNR27_RS07610	COG0848	biopolymer transport protein
CNR27_RS07620	COG1663	tetraacyldisaccharide 4'-kinase activity
CNR27_RS07630	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CNR27_RS07640	COG0322	excinuclease ABC activity
CNR27_RS07685	COG0069	glutamate synthase activity
CNR27_RS07705	COG4948	Mandelate Racemase Muconate Lactonizing
CNR27_RS07740	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CNR27_RS07770	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CNR27_RS07795	COG0859	PFAM glycosyl transferase family 9
CNR27_RS07805	COG1234	tRNA 3'-trailer cleavage
CNR27_RS07815	COG0315	cyclic pyranopterin monophosphate synthase activity
CNR27_RS07825	COG0314	molybdopterin synthase activity
CNR27_RS07845	COG2207	Transcriptional regulator
CNR27_RS07910	COG0537	adenosine 5'-monophosphoramidase activity
CNR27_RS07930	COG0714	Associated with various cellular activities
CNR27_RS07950	COG1399	metal-binding, possibly nucleic acid-binding protein
CNR27_RS07955	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CNR27_RS07960	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CNR27_RS07975	COG1028	Short-chain dehydrogenase reductase Sdr
CNR27_RS08000	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CNR27_RS08005	COG0137	argininosuccinate synthase activity
CNR27_RS08010	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CNR27_RS08015	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CNR27_RS08020	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CNR27_RS08025	COG0165	Argininosuccinate lyase
CNR27_RS08040	COG1215	transferase activity, transferring glycosyl groups
CNR27_RS08045	COG1649	PFAM Uncharacterised BCR, COG1649
CNR27_RS08045	COG0726	polysaccharide deacetylase
CNR27_RS08065	COG4988	ABC transporter
CNR27_RS08070	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CNR27_RS08075	COG0124	histidyl-tRNA synthetase
CNR27_RS08080	COG2986	histidine ammonia-lyase
CNR27_RS08105	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CNR27_RS08110	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CNR27_RS08115	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CNR27_RS08120	COG0131	Imidazoleglycerol-phosphate dehydratase
CNR27_RS08120	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CNR27_RS08125	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CNR27_RS08140	COG0140	phosphoribosyl-ATP diphosphatase activity
CNR27_RS08140	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CNR27_RS08150	COG1012	belongs to the aldehyde dehydrogenase family
CNR27_RS08160	COG1570	exodeoxyribonuclease VII activity
CNR27_RS08170	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
CNR27_RS08175	COG3290	protein histidine kinase activity
CNR27_RS08180	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CNR27_RS08185	COG0671	phosphoesterase, PA-phosphatase related
CNR27_RS08200	COG2925	Exonuclease
CNR27_RS08205	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CNR27_RS08235	COG0288	reversible hydration of carbon dioxide
CNR27_RS08255	COG2808	Putative FMN-binding domain
CNR27_RS08285	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CNR27_RS08290	COG1845	cytochrome c oxidase, subunit III
CNR27_RS08295	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CNR27_RS08305	COG0477	Major facilitator Superfamily
CNR27_RS08310	COG0360	Binds together with S18 to 16S ribosomal RNA
CNR27_RS08315	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CNR27_RS08320	COG0359	binds to the 23S rRNA
CNR27_RS08325	COG0305	Participates in initiation and elongation during chromosome replication
CNR27_RS08385	COG0339	signal peptide processing
CNR27_RS08390	COG0386	Belongs to the glutathione peroxidase family
CNR27_RS08395	COG0589	response to stress
CNR27_RS08405	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CNR27_RS08415	COG2860	membrane
CNR27_RS08425	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
CNR27_RS08450	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CNR27_RS08455	COG0084	hydrolase, TatD family'
CNR27_RS08470	COG1960	acyl-CoA dehydrogenase activity
CNR27_RS08480	COG0625	glutathione transferase activity
CNR27_RS08485	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CNR27_RS08500	COG2009	succinate dehydrogenase
CNR27_RS08510	COG1053	succinate dehydrogenase
CNR27_RS08530	COG4591	ABC-type transport system involved in lipoprotein release permease component
CNR27_RS08545	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CNR27_RS08550	COG0167	dihydroorotate dehydrogenase activity
CNR27_RS08560	COG1012	belongs to the aldehyde dehydrogenase family
CNR27_RS08575	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
CNR27_RS08580	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
CNR27_RS08585	COG0235	Class ii aldolase
CNR27_RS08590	COG0531	amino acid
CNR27_RS08595	COG0531	amino acid
CNR27_RS08605	COG0346	lactoylglutathione lyase activity
CNR27_RS08610	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CNR27_RS08615	COG0277	FAD linked oxidase domain protein
CNR27_RS08630	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CNR27_RS08655	COG1024	Enoyl-CoA hydratase
CNR27_RS08670	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CNR27_RS08685	COG0183	Belongs to the thiolase family
CNR27_RS08695	COG1960	acyl-CoA dehydrogenase activity
CNR27_RS08705	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CNR27_RS08725	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CNR27_RS08725	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CNR27_RS08725	COG1703	isobutyryl-CoA mutase activity
CNR27_RS08780	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CNR27_RS08810	COG0025	NhaP-type Na H and K H
CNR27_RS08830	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
CNR27_RS08865	COG1201	RNA secondary structure unwinding
CNR27_RS08875	COG0038	chloride channel
CNR27_RS08900	COG1716	ATPase activity
CNR27_RS08910	COG1289	transmembrane transporter activity
CNR27_RS08920	COG4221	oxidoreductase activity
CNR27_RS08945	COG0673	inositol 2-dehydrogenase activity
CNR27_RS08985	COG0584	glycerophosphoryl diester phosphodiesterase
CNR27_RS08990	COG1881	PFAM PEBP family protein
CNR27_RS09030	COG4807	Protein conserved in bacteria
CNR27_RS09035	COG1901	pseudouridine methyltransferase
CNR27_RS09055	COG3665	Urea carboxylase-associated protein
CNR27_RS09060	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CNR27_RS09090	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
CNR27_RS09095	COG1047	Peptidyl-prolyl cis-trans
CNR27_RS09100	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CNR27_RS09140	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
CNR27_RS09145	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CNR27_RS09150	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CNR27_RS09155	COG1605	Chorismate mutase
CNR27_RS09155	COG0077	Prephenate dehydratase
CNR27_RS09175	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CNR27_RS09195	COG3920	Histidine kinase
CNR27_RS09195	COG2202	Pas domain
CNR27_RS09210	COG1971	Probably functions as a manganese efflux pump
CNR27_RS09220	COG2205	protein histidine kinase activity
CNR27_RS09240	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CNR27_RS09250	COG0497	DNA recombination
CNR27_RS09255	COG1420	regulation of RNA biosynthetic process
CNR27_RS09260	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CNR27_RS09265	COG0443	Heat shock 70 kDa protein
CNR27_RS09270	COG0484	heat shock protein binding
CNR27_RS09275	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CNR27_RS09280	COG0505	Belongs to the CarA family
CNR27_RS09285	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CNR27_RS09290	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CNR27_RS09300	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CNR27_RS09310	COG3706	GGDEF domain
CNR27_RS09330	COG0784	Response regulator, receiver
CNR27_RS09330	COG2198	Histidine kinase
CNR27_RS09330	COG2205	protein histidine kinase activity
CNR27_RS09335	COG1024	Enoyl-CoA hydratase
CNR27_RS09340	COG0318	PFAM AMP-dependent synthetase and ligase
CNR27_RS09360	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CNR27_RS09365	COG0402	S-adenosylhomocysteine deaminase activity
CNR27_RS09370	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CNR27_RS09385	COG1469	GTP cyclohydrolase I activity
CNR27_RS09395	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CNR27_RS09415	COG2166	iron-sulfur cluster assembly
CNR27_RS09420	COG0415	Belongs to the DNA photolyase family
CNR27_RS09425	COG2885	chlorophyll binding
CNR27_RS09430	COG0183	Belongs to the thiolase family
CNR27_RS09435	COG1024	Enoyl-CoA hydratase
CNR27_RS09435	COG1250	3-hydroxyacyl-CoA dehydrogenase
CNR27_RS09450	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CNR27_RS09460	COG1426	Protein conserved in bacteria
CNR27_RS09470	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CNR27_RS09475	COG1160	GTP binding
CNR27_RS09480	COG0746	molybdenum cofactor guanylyltransferase activity
CNR27_RS09485	COG0303	'Molybdopterin
CNR27_RS09490	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CNR27_RS09500	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CNR27_RS09535	COG0840	transmembrane signaling receptor activity
CNR27_RS09545	COG0835	chemotaxis
CNR27_RS09550	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
CNR27_RS09555	COG0840	transmembrane signaling receptor activity
CNR27_RS09560	COG0643	Histidine kinase
CNR27_RS09560	COG2198	Histidine kinase
CNR27_RS09565	COG0745	RESPONSE REGULATOR receiver
CNR27_RS09575	COG0835	chemotaxis
CNR27_RS09580	COG1192	Involved in chromosome partitioning
CNR27_RS09585	COG1360	Flagellar Motor Protein
CNR27_RS09590	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CNR27_RS09595	COG2198	Histidine kinase
CNR27_RS09595	COG0784	Response regulator, receiver
CNR27_RS09595	COG0643	Histidine kinase
CNR27_RS09700	COG1677	Flagellar hook-basal body complex protein FliE
CNR27_RS09710	COG2197	response regulator
CNR27_RS09745	COG1216	Glycosyl transferase, family 2
CNR27_RS09745	COG0438	transferase activity, transferring glycosyl groups
CNR27_RS09765	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CNR27_RS09770	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CNR27_RS09780	COG3951	Flagellar rod assembly protein muramidase FlgJ
CNR27_RS09780	COG1705	Flagellar rod assembly protein muramidase FlgJ
CNR27_RS09790	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CNR27_RS09800	COG4787	bacterial-type flagellum-dependent cell motility
CNR27_RS09810	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CNR27_RS09815	COG1558	bacterial-type flagellum-dependent cell motility
CNR27_RS09825	COG0835	chemotaxis
CNR27_RS09825	COG0784	Response regulator, receiver
CNR27_RS09855	COG3851	Histidine kinase
CNR27_RS09860	COG3300	MHYT domain
CNR27_RS09860	COG5001	Diguanylate cyclase
CNR27_RS09870	COG2915	High frequency lysogenization protein hflD homolog
CNR27_RS09895	COG0542	response to heat
CNR27_RS09905	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CNR27_RS09915	COG0492	ferredoxin-NADP+ reductase activity
CNR27_RS09920	COG0686	Belongs to the AlaDH PNT family
CNR27_RS09925	COG1674	ftsk spoiiie
CNR27_RS09940	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CNR27_RS09955	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CNR27_RS09975	COG1187	pseudouridine synthase activity
CNR27_RS09980	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CNR27_RS09990	COG2350	Protein conserved in bacteria
CNR27_RS09995	COG1609	Transcriptional regulator
CNR27_RS10010	COG1653	transport
CNR27_RS10020	COG0395	ABC-type sugar transport system, permease component
CNR27_RS10065	COG0837	glucose binding
CNR27_RS10070	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CNR27_RS10075	COG3842	ATPase activity
CNR27_RS10090	COG0346	lactoylglutathione lyase activity
CNR27_RS10100	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
CNR27_RS10105	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CNR27_RS10115	COG0678	peroxiredoxin activity
CNR27_RS10135	COG0604	alcohol dehydrogenase
CNR27_RS10155	COG0567	Dehydrogenase, E1 component
CNR27_RS10160	COG0456	acetyltransferase
CNR27_RS10165	COG2850	peptidyl-arginine hydroxylation
CNR27_RS10180	COG0114	fumarate hydratase activity
CNR27_RS10205	COG1131	(ABC) transporter
CNR27_RS10210	COG1725	Transcriptional regulator
CNR27_RS10215	COG0386	Belongs to the glutathione peroxidase family
CNR27_RS10220	COG0545	Peptidyl-prolyl cis-trans isomerase
CNR27_RS10245	COG0646	methionine synthase
CNR27_RS10245	COG1410	methionine synthase
CNR27_RS10260	COG1960	acyl-CoA dehydrogenase activity
CNR27_RS10265	COG2902	Dehydrogenase
CNR27_RS10270	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CNR27_RS10325	COG1012	belongs to the aldehyde dehydrogenase family
CNR27_RS10330	COG1335	isochorismatase
CNR27_RS10335	COG1335	isochorismatase
CNR27_RS10350	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CNR27_RS10365	COG2855	membrane
CNR27_RS10390	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CNR27_RS10400	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CNR27_RS10415	COG0667	Aldo Keto reductase
CNR27_RS10420	COG0656	L-ascorbic acid biosynthetic process
CNR27_RS10430	COG0519	Catalyzes the synthesis of GMP from XMP
CNR27_RS10430	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CNR27_RS10460	COG1028	Short-chain dehydrogenase reductase Sdr
CNR27_RS10470	COG1028	Short-chain dehydrogenase reductase Sdr
CNR27_RS10480	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CNR27_RS10505	COG0628	permease
CNR27_RS10510	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CNR27_RS10535	COG4681	YaeQ
CNR27_RS10550	COG0189	ligase activity
CNR27_RS10555	COG0243	molybdopterin cofactor binding
CNR27_RS10655	COG0676	glucose-6-phosphate 1-epimerase activity
CNR27_RS10660	COG0583	DNA-binding transcription factor activity
CNR27_RS10665	COG1741	Belongs to the pirin family
CNR27_RS10675	COG2066	Belongs to the glutaminase family
CNR27_RS10680	COG0435	Glutathione S-transferase
CNR27_RS10700	COG5001	Diguanylate cyclase
CNR27_RS10720	COG1132	(ABC) transporter
CNR27_RS10730	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CNR27_RS10735	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CNR27_RS10740	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CNR27_RS10745	COG1956	GAF domain-containing protein
CNR27_RS10755	COG4206	TonB-dependent receptor
CNR27_RS10760	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CNR27_RS10770	COG1472	Belongs to the glycosyl hydrolase 3 family
CNR27_RS10775	COG2954	triphosphatase activity
CNR27_RS10800	COG1381	Involved in DNA repair and RecF pathway recombination
CNR27_RS10820	COG0681	Belongs to the peptidase S26 family
CNR27_RS10825	COG0481	GTPase activity
CNR27_RS10830	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CNR27_RS10845	COG1250	3-hydroxyacyl-CoA dehydrogenase
CNR27_RS10845	COG1024	Enoyl-CoA hydratase
CNR27_RS10870	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CNR27_RS10875	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CNR27_RS10880	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CNR27_RS10885	COG0488	(ABC) transporter
CNR27_RS10890	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CNR27_RS10915	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CNR27_RS10940	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CNR27_RS10945	COG1028	Short-chain dehydrogenase reductase Sdr
CNR27_RS10995	COG1304	FMN binding
CNR27_RS11040	COG2080	2 iron, 2 sulfur cluster binding
CNR27_RS11045	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CNR27_RS11050	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CNR27_RS11060	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CNR27_RS11085	COG0251	oxidation-reduction process
CNR27_RS11100	COG1028	Short-chain dehydrogenase reductase Sdr
CNR27_RS11110	COG2116	formate transmembrane transporter activity
CNR27_RS11140	COG3177	Filamentation induced by cAMP protein fic
CNR27_RS11160	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CNR27_RS11175	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CNR27_RS11200	COG0431	NADPH-dependent FMN reductase
CNR27_RS11215	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CNR27_RS11215	COG3453	Protein conserved in bacteria
CNR27_RS11250	COG1690	Belongs to the RtcB family
CNR27_RS11255	COG1451	nucleotide metabolic process
CNR27_RS11270	COG0330	HflC and HflK could
CNR27_RS11275	COG0330	HflC and HflK could
CNR27_RS11280	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CNR27_RS11285	COG1923	regulation of RNA biosynthetic process
CNR27_RS11290	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CNR27_RS11295	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CNR27_RS11300	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CNR27_RS11305	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CNR27_RS11310	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CNR27_RS11315	COG1534	Rna-binding protein
CNR27_RS11330	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CNR27_RS11360	COG0544	peptidyl-prolyl cis-trans isomerase activity
CNR27_RS11400	COG0473	3-isopropylmalate dehydrogenase activity
CNR27_RS11415	COG4783	chaperone-mediated protein folding
CNR27_RS11420	COG0745	RESPONSE REGULATOR receiver
CNR27_RS11450	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CNR27_RS11455	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CNR27_RS11455	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CNR27_RS11460	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CNR27_RS11470	COG3118	belongs to the thioredoxin family
CNR27_RS11475	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CNR27_RS11480	COG1393	Belongs to the ArsC family
CNR27_RS11495	COG0024	Methionine aminopeptidase
CNR27_RS11525	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CNR27_RS11530	COG0776	regulation of translation
CNR27_RS11540	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CNR27_RS11555	COG2957	Belongs to the agmatine deiminase family
CNR27_RS11560	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CNR27_RS11575	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CNR27_RS11585	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CNR27_RS11605	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CNR27_RS11605	COG0316	Belongs to the HesB IscA family
CNR27_RS11620	COG1530	ribonuclease E activity
CNR27_RS11630	COG1999	signal sequence binding
CNR27_RS11635	COG0436	Aminotransferase
CNR27_RS11665	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
CNR27_RS11670	COG1138	Cytochrome C-type biogenesis protein
CNR27_RS11675	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CNR27_RS11690	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CNR27_RS11735	COG3243	poly(R)-hydroxyalkanoic acid synthase
CNR27_RS11745	COG1183	phosphatidylcholine synthase activity
CNR27_RS11790	COG2197	response regulator
CNR27_RS11795	COG4585	Histidine kinase
CNR27_RS11810	COG2894	cell division
CNR27_RS11815	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CNR27_RS11830	COG2814	Major facilitator Superfamily
CNR27_RS11835	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CNR27_RS11835	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CNR27_RS11840	COG5001	Diguanylate cyclase
CNR27_RS11850	COG0528	UMP kinase activity
CNR27_RS11860	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CNR27_RS11865	COG0575	Belongs to the CDS family
CNR27_RS11870	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CNR27_RS11885	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CNR27_RS11900	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CNR27_RS11915	COG0825	malonyl-CoA metabolic process
CNR27_RS11925	COG1902	pentaerythritol trinitrate reductase activity
CNR27_RS11935	COG1722	exodeoxyribonuclease VII activity
CNR27_RS11940	COG0142	geranyltranstransferase activity
CNR27_RS11955	COG0312	modulator of DNA gyrase
CNR27_RS11965	COG0312	modulator of DNA gyrase
CNR27_RS11980	COG0424	maF-like protein
CNR27_RS11990	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CNR27_RS12000	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CNR27_RS12015	COG0495	leucyl-tRNA aminoacylation
CNR27_RS12045	COG3118	belongs to the thioredoxin family
CNR27_RS12060	COG0515	serine threonine protein kinase
CNR27_RS12060	COG2815	serine threonine protein kinase
CNR27_RS12090	COG0612	Peptidase, M16
CNR27_RS12095	COG1301	dicarboxylic acid transport
CNR27_RS12105	COG1028	Short-chain dehydrogenase reductase Sdr
CNR27_RS12115	COG1981	membrane
CNR27_RS12190	COG0714	Associated with various cellular activities
CNR27_RS12220	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CNR27_RS12220	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CNR27_RS12225	COG2223	nitrite transmembrane transporter activity
CNR27_RS12235	COG0243	molybdopterin cofactor binding
CNR27_RS12255	COG2211	Major facilitator Superfamily
CNR27_RS12260	COG3693	PFAM glycoside hydrolase, family 10
CNR27_RS12270	COG1472	Belongs to the glycosyl hydrolase 3 family
CNR27_RS12285	COG3661	Belongs to the glycosyl hydrolase 67 family
CNR27_RS12290	COG1609	Transcriptional regulator
CNR27_RS12300	COG1070	Carbohydrate kinase
CNR27_RS12305	COG1028	Short-chain dehydrogenase reductase Sdr
CNR27_RS12310	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CNR27_RS12310	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CNR27_RS12320	COG1535	isochorismatase
CNR27_RS12320	COG3433	isochorismatase activity
CNR27_RS12325	COG1021	2,3-dihydroxybenzoate-AMP ligase
CNR27_RS12330	COG1169	isochorismate synthase
CNR27_RS12345	COG2819	hydrolase of the alpha beta superfamily
CNR27_RS12355	COG4558	Periplasmic binding protein
CNR27_RS12360	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CNR27_RS12365	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CNR27_RS12400	COG2969	positive regulation of protein catabolic process
CNR27_RS12405	COG0625	glutathione transferase activity
CNR27_RS12410	COG2857	Cytochrome c1
CNR27_RS12415	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CNR27_RS12420	COG0723	plastoquinol--plastocyanin reductase activity
CNR27_RS12425	COG0741	lytic transglycosylase activity
CNR27_RS12430	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CNR27_RS12435	COG1702	phosphate starvation-inducible protein PhoH
CNR27_RS12440	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CNR27_RS12445	COG4535	Mg2 and Co2 transporter CorC
CNR27_RS12455	COG1082	Xylose isomerase domain protein TIM barrel
CNR27_RS12460	COG0598	Magnesium transport protein CorA
CNR27_RS12465	COG3932	Exopolysaccharide synthesis, ExoD
CNR27_RS12470	COG1966	Carbon starvation protein
CNR27_RS12475	COG2879	small protein
CNR27_RS12485	COG1506	peptidase
CNR27_RS12485	COG0823	Involved in the tonB-independent uptake of proteins
CNR27_RS12495	COG3104	oligopeptide transport
CNR27_RS12520	COG0629	single-stranded DNA binding
CNR27_RS12525	COG0142	geranyltranstransferase activity
CNR27_RS12545	COG0527	aspartate kinase activity
CNR27_RS12550	COG0384	phenazine biosynthesis protein PhzF
CNR27_RS12555	COG0384	phenazine biosynthesis protein PhzF
CNR27_RS12565	COG1764	response to oxidative stress
CNR27_RS12620	COG1215	transferase activity, transferring glycosyl groups
CNR27_RS12645	COG0719	Fe-S assembly protein
CNR27_RS12650	COG0396	ATPase activity
CNR27_RS12660	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CNR27_RS12670	COG2146	nitrite reductase [NAD(P)H] activity
CNR27_RS12675	COG4771	TonB-dependent receptor
CNR27_RS12685	COG1555	photosystem II stabilization
CNR27_RS12695	COG0529	Catalyzes the synthesis of activated sulfate
CNR27_RS12695	COG2895	sulfate adenylyltransferase (ATP) activity
CNR27_RS12700	COG0175	sulfate reduction
CNR27_RS12705	COG0475	glutathione-regulated potassium exporter activity
CNR27_RS12720	COG1960	acyl-CoA dehydrogenase activity
CNR27_RS12735	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CNR27_RS12765	COG0072	phenylalanine-tRNA ligase activity
CNR27_RS12765	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CNR27_RS12770	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CNR27_RS12775	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CNR27_RS12785	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CNR27_RS12790	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CNR27_RS12810	COG0366	Alpha amylase catalytic
CNR27_RS12840	COG0556	nucleotide-excision repair
CNR27_RS12885	COG1611	Belongs to the LOG family
CNR27_RS12895	COG2095	MarC family integral membrane protein
CNR27_RS12905	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CNR27_RS12920	COG0784	Response regulator, receiver
CNR27_RS12920	COG3437	response regulator, receiver
CNR27_RS12950	COG1132	(ABC) transporter
CNR27_RS12965	COG2264	protein methyltransferase activity
CNR27_RS12980	COG1205	dead DEAH box helicase
CNR27_RS12980	COG1111	helicase
CNR27_RS12985	COG0693	protein deglycase activity
CNR27_RS13010	COG5507	3-demethylubiquinone-9 3-methyltransferase
CNR27_RS13020	COG1285	pathogenesis
CNR27_RS13055	COG3386	PFAM SMP-30 Gluconolaconase
CNR27_RS13060	COG3384	dioxygenase
CNR27_RS13065	COG0477	Major facilitator Superfamily
CNR27_RS13115	COG3795	YCII-related domain
CNR27_RS13170	COG2972	Histidine kinase
CNR27_RS13175	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CNR27_RS13190	COG1228	amidohydrolase
CNR27_RS13205	COG4771	TonB-dependent receptor
CNR27_RS13210	COG0735	belongs to the Fur family
CNR27_RS13220	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CNR27_RS13230	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CNR27_RS13235	COG0405	Gamma-glutamyltransferase
CNR27_RS13240	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CNR27_RS13255	COG0742	ribosomal rna small subunit methyltransferase
CNR27_RS13260	COG0552	protein localization to endoplasmic reticulum
CNR27_RS13275	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
CNR27_RS13285	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CNR27_RS13290	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CNR27_RS13295	COG0628	permease
CNR27_RS13305	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CNR27_RS13310	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CNR27_RS13330	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CNR27_RS13340	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CNR27_RS13340	COG0517	IMP dehydrogenase activity
CNR27_RS13345	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CNR27_RS13360	COG1137	ATPase activity
CNR27_RS13375	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CNR27_RS13385	COG1660	Displays ATPase and GTPase activities
CNR27_RS13395	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CNR27_RS13400	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CNR27_RS13405	COG2239	Acts as a magnesium transporter
CNR27_RS13430	COG1113	amino acid transport
CNR27_RS13440	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CNR27_RS13455	COG1047	Peptidyl-prolyl cis-trans
CNR27_RS13460	COG0519	Catalyzes the synthesis of GMP from XMP
CNR27_RS13465	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CNR27_RS13495	COG2910	NAD(P)H-binding
CNR27_RS13505	COG0259	pyridoxamine-phosphate oxidase activity
CNR27_RS13515	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CNR27_RS13545	COG1201	RNA secondary structure unwinding
CNR27_RS13550	COG1793	dna ligase
CNR27_RS13555	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CNR27_RS13555	COG1793	dna ligase
CNR27_RS13585	COG1760	l-serine dehydratase
CNR27_RS13595	COG0527	aspartate kinase activity
CNR27_RS13595	COG0460	homoserine dehydrogenase
CNR27_RS13600	COG0626	cystathionine gamma-synthase activity
CNR27_RS13605	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CNR27_RS13615	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CNR27_RS13620	COG1272	protein, Hemolysin III
CNR27_RS13635	COG0463	Glycosyl transferase, family 2
CNR27_RS13645	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CNR27_RS13665	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
CNR27_RS13675	COG1960	acyl-CoA dehydrogenase activity
CNR27_RS13695	COG0501	Belongs to the peptidase M48B family
CNR27_RS13700	COG1704	LemA family
CNR27_RS13720	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CNR27_RS13730	COG0330	HflC and HflK could
CNR27_RS13740	COG0667	Aldo Keto reductase
CNR27_RS13750	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CNR27_RS13755	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CNR27_RS13760	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CNR27_RS13770	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CNR27_RS13775	COG2308	Evidence 4 Homologs of previously reported genes of
CNR27_RS13800	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CNR27_RS13820	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CNR27_RS13830	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CNR27_RS13840	COG0745	RESPONSE REGULATOR receiver
CNR27_RS13870	COG2022	thiamine diphosphate biosynthetic process
CNR27_RS13875	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CNR27_RS13880	COG0471	metal ion transport
CNR27_RS13880	COG3273	potassium ion transport
CNR27_RS13920	COG1115	amino acid carrier protein
CNR27_RS13930	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CNR27_RS13950	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CNR27_RS13955	COG3588	fructose-bisphosphate aldolase
CNR27_RS13960	COG0469	pyruvate kinase activity
CNR27_RS13965	COG0126	phosphoglycerate kinase activity
CNR27_RS13970	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CNR27_RS13975	COG3047	cAMP biosynthetic process
CNR27_RS14020	COG2948	multi-organism process
CNR27_RS14030	COG3736	Type IV secretory pathway, component VirB8
CNR27_RS14060	COG0725	ABC transporter, periplasmic molybdate-binding protein
CNR27_RS14065	COG4149	molybdate abc transporter
CNR27_RS14070	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CNR27_RS14085	COG0427	acetyl-CoA hydrolase
CNR27_RS14090	COG0271	Belongs to the BolA IbaG family
CNR27_RS14100	COG1301	dicarboxylic acid transport
CNR27_RS14105	COG0514	ATP-dependent DNA helicase (RecQ)
CNR27_RS14130	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CNR27_RS14135	COG0602	queuosine metabolic process
CNR27_RS14145	COG2885	chlorophyll binding
CNR27_RS14160	COG0848	biopolymer transport protein
CNR27_RS14170	COG0824	Thioesterase
CNR27_RS14175	COG2255	four-way junction helicase activity
CNR27_RS14180	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CNR27_RS14195	COG0632	four-way junction helicase activity
CNR27_RS14200	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CNR27_RS14205	COG0217	transcriptional regulatory protein
CNR27_RS14220	COG1764	response to oxidative stress
CNR27_RS14230	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CNR27_RS14260	COG0488	(ABC) transporter
CNR27_RS14265	COG4206	TonB-dependent receptor
CNR27_RS14270	COG4651	solute:proton antiporter activity
CNR27_RS14270	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CNR27_RS14275	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CNR27_RS14280	COG1090	epimerase
CNR27_RS14285	COG0542	response to heat
CNR27_RS14305	COG3387	PFAM Glycoside hydrolase 15-related
CNR27_RS14310	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
CNR27_RS14320	COG0596	Alpha beta hydrolase
CNR27_RS14330	COG1741	Belongs to the pirin family
CNR27_RS14335	COG1335	isochorismatase
CNR27_RS14340	COG0583	DNA-binding transcription factor activity
CNR27_RS14360	COG0564	pseudouridine synthase activity
CNR27_RS14365	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CNR27_RS14385	COG0297	glycogen (starch) synthase activity
CNR27_RS14390	COG1215	transferase activity, transferring glycosyl groups
CNR27_RS14390	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CNR27_RS14395	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CNR27_RS14395	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CNR27_RS14400	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CNR27_RS14405	COG0242	peptide deformylase activity
CNR27_RS14410	COG1652	LysM domain
CNR27_RS14415	COG0758	DNA mediated transformation
CNR27_RS14430	COG1714	RDD family
CNR27_RS14435	COG1754	DNA topoisomerase type I activity
CNR27_RS14435	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CNR27_RS14440	COG0009	L-threonylcarbamoyladenylate synthase
CNR27_RS14445	COG0069	glutamate synthase activity
CNR27_RS14445	COG0070	glutamate synthase
CNR27_RS14445	COG0067	glutamate synthase
CNR27_RS14450	COG0493	'glutamate synthase
CNR27_RS14465	COG1028	Short-chain dehydrogenase reductase Sdr
CNR27_RS14480	COG2755	lipolytic protein G-D-S-L family
CNR27_RS14490	COG1028	Short-chain dehydrogenase reductase Sdr
CNR27_RS14495	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
CNR27_RS14500	COG1609	Transcriptional regulator
CNR27_RS14505	COG3507	Belongs to the glycosyl hydrolase 43 family
CNR27_RS14510	COG0477	Major facilitator Superfamily
CNR27_RS14530	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CNR27_RS14540	COG2755	lipolytic protein G-D-S-L family
CNR27_RS14540	COG0657	acetylesterase activity
CNR27_RS14550	COG2755	lipolytic protein G-D-S-L family
CNR27_RS14575	COG4677	pectinesterase activity
CNR27_RS14590	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CNR27_RS14595	COG0616	signal peptide processing
CNR27_RS14600	COG0534	Mate efflux family protein
CNR27_RS14615	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CNR27_RS14625	COG0456	acetyltransferase
CNR27_RS14635	COG1183	phosphatidylcholine synthase activity
CNR27_RS14660	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CNR27_RS14665	COG1127	ABC transporter
CNR27_RS14670	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CNR27_RS14670	COG3218	ABC-type transport auxiliary lipoprotein component
CNR27_RS14690	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CNR27_RS14730	COG0463	Glycosyl transferase, family 2
CNR27_RS14745	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CNR27_RS14760	COG0438	transferase activity, transferring glycosyl groups
CNR27_RS14760	COG1216	Glycosyl transferase, family 2
CNR27_RS14825	COG2165	general secretion pathway protein
CNR27_RS14830	COG1459	type II secretion system
CNR27_RS14865	COG0626	cystathionine gamma-synthase activity
CNR27_RS14895	COG0625	glutathione transferase activity
CNR27_RS14915	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CNR27_RS14920	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CNR27_RS14925	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
CNR27_RS14930	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
CNR27_RS14935	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CNR27_RS14945	COG0730	response to heat
CNR27_RS14960	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CNR27_RS14980	COG1597	lipid kinase activity
CNR27_RS14985	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CNR27_RS14990	COG0484	heat shock protein binding
CNR27_RS14995	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CNR27_RS15005	COG0612	Peptidase, M16
CNR27_RS15035	COG2111	Na H antiporter
CNR27_RS15035	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CNR27_RS15040	COG1006	Multisubunit Na H antiporter MnhC subunit
CNR27_RS15045	COG0651	ATP synthesis coupled electron transport
CNR27_RS15050	COG1863	multisubunit Na H antiporter MnhE subunit
CNR27_RS15055	COG2212	antiporter activity
CNR27_RS15060	COG1320	monovalent cation:proton antiporter activity
CNR27_RS15070	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CNR27_RS15085	COG3104	oligopeptide transport
CNR27_RS15090	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity