locus-tag	class	description
LuPra_RS00010	COG0592	DNA-directed DNA polymerase activity
LuPra_RS00020	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LuPra_RS00035	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LuPra_RS00040	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LuPra_RS00045	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LuPra_RS00060	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LuPra_RS00065	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LuPra_RS00090	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LuPra_RS00095	COG0066	3-isopropylmalate dehydratase activity
LuPra_RS00110	COG0583	DNA-binding transcription factor activity
LuPra_RS00115	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LuPra_RS00120	COG0473	3-isopropylmalate dehydrogenase activity
LuPra_RS00145	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LuPra_RS00145	COG4651	solute:proton antiporter activity
LuPra_RS00175	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LuPra_RS00245	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LuPra_RS00250	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LuPra_RS00260	COG0402	S-adenosylhomocysteine deaminase activity
LuPra_RS00275	COG0668	transmembrane transport
LuPra_RS00285	COG1028	Short-chain dehydrogenase reductase Sdr
LuPra_RS00295	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LuPra_RS00300	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LuPra_RS00375	COG0432	Pfam Uncharacterised protein family UPF0047
LuPra_RS00400	COG3227	Zinc metalloprotease (Elastase)
LuPra_RS00420	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
LuPra_RS00425	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
LuPra_RS00430	COG0235	Class ii aldolase
LuPra_RS00435	COG1678	Uncharacterized ACR, COG1678
LuPra_RS00485	COG5002	protein histidine kinase activity
LuPra_RS00520	COG0713	ATP synthesis coupled electron transport
LuPra_RS00525	COG0651	ATP synthesis coupled electron transport
LuPra_RS00535	COG0651	ATP synthesis coupled electron transport
LuPra_RS00545	COG1007	ATP synthesis coupled electron transport
LuPra_RS00555	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LuPra_RS00560	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LuPra_RS00565	COG0649	NAD binding
LuPra_RS00585	COG1034	ATP synthesis coupled electron transport
LuPra_RS00590	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
LuPra_RS00595	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LuPra_RS00630	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LuPra_RS00650	COG0545	Peptidyl-prolyl cis-trans isomerase
LuPra_RS00655	COG1136	(ABC) transporter
LuPra_RS00655	COG0577	efflux transmembrane transporter activity
LuPra_RS00670	COG2268	Band 7 protein
LuPra_RS00685	COG0437	4 iron, 4 sulfur cluster binding
LuPra_RS00690	COG0243	molybdopterin cofactor binding
LuPra_RS00695	COG2223	nitrite transmembrane transporter activity
LuPra_RS00705	COG4650	regulator
LuPra_RS00710	COG0430	RNA-3'-phosphate cyclase activity
LuPra_RS00720	COG3119	arylsulfatase activity
LuPra_RS00725	COG0577	efflux transmembrane transporter activity
LuPra_RS00725	COG1136	(ABC) transporter
LuPra_RS00745	COG0577	efflux transmembrane transporter activity
LuPra_RS00745	COG1136	(ABC) transporter
LuPra_RS00750	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LuPra_RS00755	COG0577	efflux transmembrane transporter activity
LuPra_RS00755	COG1136	(ABC) transporter
LuPra_RS00780	COG1028	Short-chain dehydrogenase reductase Sdr
LuPra_RS00795	COG3119	arylsulfatase activity
LuPra_RS00815	COG2382	esterase
LuPra_RS00815	COG3693	PFAM glycoside hydrolase, family 10
LuPra_RS00820	COG2124	cytochrome p450
LuPra_RS00840	COG0577	efflux transmembrane transporter activity
LuPra_RS00840	COG1136	(ABC) transporter
LuPra_RS00860	COG1940	carbohydrate kinase activity
LuPra_RS00875	COG1228	amidohydrolase
LuPra_RS00905	COG0644	oxidoreductase
LuPra_RS00920	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LuPra_RS00940	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LuPra_RS00945	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LuPra_RS00955	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LuPra_RS01010	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LuPra_RS01010	COG1796	DNA polymerase
LuPra_RS01015	COG2234	aminopeptidase activity
LuPra_RS01020	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LuPra_RS01055	COG1401	restriction endodeoxyribonuclease activity
LuPra_RS01085	COG2514	catechol 2,3-dioxygenase activity
LuPra_RS01100	COG0823	Involved in the tonB-independent uptake of proteins
LuPra_RS01110	COG0515	serine threonine protein kinase
LuPra_RS01125	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
LuPra_RS01135	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LuPra_RS01140	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LuPra_RS01155	COG2020	methyltransferase activity
LuPra_RS01160	COG4948	Mandelate Racemase Muconate Lactonizing
LuPra_RS01170	COG3525	Glycosyl hydrolase, family 20, catalytic domain
LuPra_RS01185	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LuPra_RS01220	COG2204	response regulator
LuPra_RS01225	COG3852	Histidine kinase
LuPra_RS01245	COG0437	4 iron, 4 sulfur cluster binding
LuPra_RS01260	COG1073	alpha beta
LuPra_RS01275	COG0745	RESPONSE REGULATOR receiver
LuPra_RS01285	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
LuPra_RS01295	COG1028	Short-chain dehydrogenase reductase Sdr
LuPra_RS01300	COG1940	carbohydrate kinase activity
LuPra_RS01305	COG4821	SIS domain
LuPra_RS01315	COG0076	glutamate decarboxylase activity
LuPra_RS01385	COG1621	beta-fructofuranosidase activity
LuPra_RS01390	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LuPra_RS01405	COG1160	GTP binding
LuPra_RS01410	COG3279	Response regulator of the LytR AlgR family
LuPra_RS01415	COG3275	phosphorelay sensor kinase activity
LuPra_RS01460	COG0745	RESPONSE REGULATOR receiver
LuPra_RS01525	COG0673	inositol 2-dehydrogenase activity
LuPra_RS01560	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LuPra_RS01575	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LuPra_RS01580	COG3119	arylsulfatase activity
LuPra_RS01590	COG3534	alpha-L-arabinofuranosidase
LuPra_RS01610	COG0154	amidase activity
LuPra_RS01630	COG1904	glucuronate isomerase
LuPra_RS01640	COG2764	glyoxalase bleomycin resistance protein dioxygenase
LuPra_RS01660	COG4191	Histidine kinase
LuPra_RS01665	COG2204	response regulator
LuPra_RS01670	COG0577	efflux transmembrane transporter activity
LuPra_RS01675	COG0577	efflux transmembrane transporter activity
LuPra_RS01675	COG1136	(ABC) transporter
LuPra_RS01680	COG1136	(ABC) transporter
LuPra_RS01695	COG3852	Histidine kinase
LuPra_RS01700	COG2204	response regulator
LuPra_RS01720	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LuPra_RS01730	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
LuPra_RS01735	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LuPra_RS01745	COG3964	amidohydrolase
LuPra_RS01760	COG1012	belongs to the aldehyde dehydrogenase family
LuPra_RS01765	COG3119	arylsulfatase activity
LuPra_RS01770	COG0405	Gamma-glutamyltransferase
LuPra_RS01775	COG3119	arylsulfatase activity
LuPra_RS01790	COG4152	abc transporter atp-binding protein
LuPra_RS01795	COG2815	serine threonine protein kinase
LuPra_RS01795	COG0515	serine threonine protein kinase
LuPra_RS01800	COG2815	serine threonine protein kinase
LuPra_RS01800	COG0515	serine threonine protein kinase
LuPra_RS01825	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LuPra_RS01860	COG3119	arylsulfatase activity
LuPra_RS01885	COG0437	4 iron, 4 sulfur cluster binding
LuPra_RS01920	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LuPra_RS01925	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LuPra_RS01945	COG0492	ferredoxin-NADP+ reductase activity
LuPra_RS01950	COG4191	Histidine kinase
LuPra_RS01950	COG0784	Response regulator, receiver
LuPra_RS01980	COG1136	(ABC) transporter
LuPra_RS01980	COG0577	efflux transmembrane transporter activity
LuPra_RS01985	COG1136	(ABC) transporter
LuPra_RS01990	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LuPra_RS01995	COG1956	GAF domain-containing protein
LuPra_RS02000	COG2353	YceI-like domain
LuPra_RS02005	COG1793	dna ligase
LuPra_RS02010	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
LuPra_RS02010	COG1793	dna ligase
LuPra_RS02020	COG0405	Gamma-glutamyltransferase
LuPra_RS02025	COG1131	(ABC) transporter
LuPra_RS02035	COG2897	thiosulfate sulfurtransferase activity
LuPra_RS02055	COG1505	serine-type exopeptidase activity
LuPra_RS02070	COG1028	Short-chain dehydrogenase reductase Sdr
LuPra_RS02080	COG3279	Response regulator of the LytR AlgR family
LuPra_RS02085	COG3275	phosphorelay sensor kinase activity
LuPra_RS02135	COG0277	FAD linked oxidase domain protein
LuPra_RS02180	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LuPra_RS02190	COG0318	PFAM AMP-dependent synthetase and ligase
LuPra_RS02215	COG1028	Short-chain dehydrogenase reductase Sdr
LuPra_RS02230	COG2197	response regulator
LuPra_RS02235	COG4585	Histidine kinase
LuPra_RS02240	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LuPra_RS02305	COG0586	Pfam SNARE associated Golgi protein
LuPra_RS02320	COG2252	PERMEase
LuPra_RS02325	COG0165	Argininosuccinate lyase
LuPra_RS02335	COG0823	Involved in the tonB-independent uptake of proteins
LuPra_RS02335	COG1506	peptidase
LuPra_RS02345	COG2133	pyrroloquinoline quinone binding
LuPra_RS02360	COG0154	amidase activity
LuPra_RS02370	COG0436	Aminotransferase
LuPra_RS02385	COG1764	response to oxidative stress
LuPra_RS02390	COG0405	Gamma-glutamyltransferase
LuPra_RS02395	COG2318	DinB family
LuPra_RS02400	COG0667	Aldo Keto reductase
LuPra_RS02415	COG0148	phosphopyruvate hydratase activity
LuPra_RS02435	COG0739	heme binding
LuPra_RS02450	COG4206	TonB-dependent receptor
LuPra_RS02455	COG0617	tRNA 3'-terminal CCA addition
LuPra_RS02470	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LuPra_RS02470	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LuPra_RS02485	COG0745	RESPONSE REGULATOR receiver
LuPra_RS02490	COG5002	protein histidine kinase activity
LuPra_RS02500	COG2814	Major facilitator Superfamily
LuPra_RS02535	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LuPra_RS02555	COG1136	(ABC) transporter
LuPra_RS02575	COG0444	Belongs to the ABC transporter superfamily
LuPra_RS02585	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LuPra_RS02590	COG0148	phosphopyruvate hydratase activity
LuPra_RS02595	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LuPra_RS02615	COG2204	response regulator
LuPra_RS02620	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LuPra_RS02630	COG0438	transferase activity, transferring glycosyl groups
LuPra_RS02650	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
LuPra_RS02655	COG1366	Belongs to the anti-sigma-factor antagonist family
LuPra_RS02660	COG0828	Belongs to the bacterial ribosomal protein bS21 family
LuPra_RS02665	COG0151	Belongs to the GarS family
LuPra_RS02670	COG0820	rRNA (adenine-C2-)-methyltransferase activity
LuPra_RS02675	COG0612	Peptidase, M16
LuPra_RS02680	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LuPra_RS02685	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LuPra_RS02690	COG0047	phosphoribosylformylglycinamidine synthase activity
LuPra_RS02700	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LuPra_RS02705	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LuPra_RS02715	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LuPra_RS02725	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LuPra_RS02730	COG1408	metallophosphoesterase
LuPra_RS02745	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LuPra_RS02785	COG0300	oxidoreductase activity
LuPra_RS02830	COG0217	transcriptional regulatory protein
LuPra_RS02835	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
LuPra_RS02840	COG0632	four-way junction helicase activity
LuPra_RS02845	COG2255	four-way junction helicase activity
LuPra_RS02850	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LuPra_RS02855	COG2197	response regulator
LuPra_RS02865	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LuPra_RS02870	COG0366	Alpha amylase catalytic
LuPra_RS02900	COG3119	arylsulfatase activity
LuPra_RS02910	COG0582	viral genome integration into host DNA
LuPra_RS02925	COG3657	addiction module killer protein
LuPra_RS02995	COG0793	Belongs to the peptidase S41A family
LuPra_RS02995	COG4946	Tricorn protease homolog
LuPra_RS03030	COG0037	tRNA processing
LuPra_RS03035	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LuPra_RS03045	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LuPra_RS03055	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LuPra_RS03075	COG0235	Class ii aldolase
LuPra_RS03080	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
LuPra_RS03085	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
LuPra_RS03100	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LuPra_RS03105	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LuPra_RS03125	COG2226	methyltransferase
LuPra_RS03130	COG0531	amino acid
LuPra_RS03135	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LuPra_RS03180	COG0602	queuosine metabolic process
LuPra_RS03185	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LuPra_RS03200	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LuPra_RS03220	COG0842	Transport permease protein
LuPra_RS03225	COG0842	Transport permease protein
LuPra_RS03225	COG1129	ABC transporter
LuPra_RS03230	COG0640	Transcriptional regulator
LuPra_RS03255	COG2885	chlorophyll binding
LuPra_RS03260	COG0284	orotidine-5'-phosphate decarboxylase activity
LuPra_RS03265	COG0167	dihydroorotate dehydrogenase activity
LuPra_RS03285	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LuPra_RS03290	COG0540	Belongs to the ATCase OTCase family
LuPra_RS03295	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LuPra_RS03300	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LuPra_RS03310	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LuPra_RS03315	COG0297	glycogen (starch) synthase activity
LuPra_RS03335	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LuPra_RS03340	COG0101	tRNA pseudouridine synthase activity
LuPra_RS03345	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LuPra_RS03350	COG0575	Belongs to the CDS family
LuPra_RS03360	COG0750	zinc metalloprotease
LuPra_RS03380	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LuPra_RS03435	COG1012	belongs to the aldehyde dehydrogenase family
LuPra_RS03445	COG2226	methyltransferase
LuPra_RS03450	COG1215	transferase activity, transferring glycosyl groups
LuPra_RS03460	COG2304	oxidoreductase activity
LuPra_RS03465	COG0793	Belongs to the peptidase S41A family
LuPra_RS03465	COG4946	Tricorn protease homolog
LuPra_RS03525	COG2096	Adenosyltransferase
LuPra_RS03530	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LuPra_RS03535	COG0653	protein targeting
LuPra_RS03550	COG0427	acetyl-CoA hydrolase
LuPra_RS03590	COG0783	Belongs to the Dps family
LuPra_RS03600	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
LuPra_RS03610	COG1506	peptidase
LuPra_RS03610	COG4946	Tricorn protease homolog
LuPra_RS03610	COG0823	Involved in the tonB-independent uptake of proteins
LuPra_RS03625	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LuPra_RS03630	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LuPra_RS03640	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LuPra_RS03645	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LuPra_RS03650	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LuPra_RS03655	COG1438	arginine binding
LuPra_RS03660	COG0137	argininosuccinate synthase activity
LuPra_RS03665	COG0165	Argininosuccinate lyase
LuPra_RS03675	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
LuPra_RS03690	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LuPra_RS03700	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LuPra_RS03705	COG0546	phosphoglycolate phosphatase activity
LuPra_RS03710	COG1321	iron dependent repressor
LuPra_RS03715	COG2226	methyltransferase
LuPra_RS03735	COG1322	Protein conserved in bacteria
LuPra_RS03750	COG1032	radical SAM domain protein
LuPra_RS03755	COG5000	phosphorelay sensor kinase activity
LuPra_RS03770	COG0577	efflux transmembrane transporter activity
LuPra_RS03770	COG1136	(ABC) transporter
LuPra_RS03775	COG1136	(ABC) transporter
LuPra_RS03835	COG0316	Belongs to the HesB IscA family
LuPra_RS03860	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LuPra_RS03865	COG1120	ATPase activity
LuPra_RS03870	COG4771	TonB-dependent receptor
LuPra_RS03880	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
LuPra_RS03925	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
LuPra_RS03955	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LuPra_RS03960	COG1073	alpha beta
LuPra_RS03965	COG1305	Transglutaminase-like
LuPra_RS04015	COG0745	RESPONSE REGULATOR receiver
LuPra_RS04025	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LuPra_RS04040	COG1848	Toxic component of a toxin-antitoxin (TA) module. An RNase
LuPra_RS04045	COG2311	Membrane
LuPra_RS04080	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LuPra_RS04085	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LuPra_RS04090	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
LuPra_RS04105	COG0303	'Molybdopterin
LuPra_RS04110	COG0521	Mo-molybdopterin cofactor biosynthetic process
LuPra_RS04205	COG4585	Histidine kinase
LuPra_RS04210	COG2197	response regulator
LuPra_RS04235	COG2815	serine threonine protein kinase
LuPra_RS04235	COG0515	serine threonine protein kinase
LuPra_RS04275	COG0823	Involved in the tonB-independent uptake of proteins
LuPra_RS04315	COG0640	Transcriptional regulator
LuPra_RS04325	COG0612	Peptidase, M16
LuPra_RS04360	COG0612	Peptidase, M16
LuPra_RS04405	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LuPra_RS04410	COG0793	Belongs to the peptidase S41A family
LuPra_RS04410	COG3409	Peptidoglycan-binding domain 1 protein
LuPra_RS04415	COG2815	serine threonine protein kinase
LuPra_RS04415	COG0515	serine threonine protein kinase
LuPra_RS04445	COG1505	serine-type exopeptidase activity
LuPra_RS04470	COG0577	efflux transmembrane transporter activity
LuPra_RS04470	COG1136	(ABC) transporter
LuPra_RS04515	COG1953	Uracil, thiamine, allantoin
LuPra_RS04525	COG1012	belongs to the aldehyde dehydrogenase family
LuPra_RS04535	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LuPra_RS04545	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LuPra_RS04560	COG2267	carboxylic ester hydrolase activity
LuPra_RS04635	COG0673	inositol 2-dehydrogenase activity
LuPra_RS04640	COG0463	Glycosyl transferase, family 2
LuPra_RS04665	COG1136	(ABC) transporter
LuPra_RS04665	COG0577	efflux transmembrane transporter activity
LuPra_RS04705	COG0515	serine threonine protein kinase
LuPra_RS04705	COG2815	serine threonine protein kinase
LuPra_RS04730	COG0515	serine threonine protein kinase
LuPra_RS04730	COG2815	serine threonine protein kinase
LuPra_RS04740	COG1595	DNA-templated transcription, initiation
LuPra_RS04785	COG0577	efflux transmembrane transporter activity
LuPra_RS04785	COG1136	(ABC) transporter
LuPra_RS04800	COG0745	RESPONSE REGULATOR receiver
LuPra_RS04820	COG1136	(ABC) transporter
LuPra_RS04820	COG0577	efflux transmembrane transporter activity
LuPra_RS04835	COG0515	serine threonine protein kinase
LuPra_RS04865	COG2267	carboxylic ester hydrolase activity
LuPra_RS04880	COG2814	Major facilitator Superfamily
LuPra_RS04885	COG0475	glutathione-regulated potassium exporter activity
LuPra_RS04890	COG2815	serine threonine protein kinase
LuPra_RS04890	COG0515	serine threonine protein kinase
LuPra_RS04920	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LuPra_RS04930	COG0515	serine threonine protein kinase
LuPra_RS04945	COG1136	(ABC) transporter
LuPra_RS04945	COG0577	efflux transmembrane transporter activity
LuPra_RS04950	COG0281	malic enzyme
LuPra_RS04970	COG1136	(ABC) transporter
LuPra_RS04970	COG0577	efflux transmembrane transporter activity
LuPra_RS04975	COG0577	efflux transmembrane transporter activity
LuPra_RS04975	COG1136	(ABC) transporter
LuPra_RS04995	COG5002	protein histidine kinase activity
LuPra_RS04995	COG5001	Diguanylate cyclase
LuPra_RS04995	COG3447	MASE1 domain protein
LuPra_RS05015	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LuPra_RS05025	COG0557	exoribonuclease II activity
LuPra_RS05035	COG4948	Mandelate Racemase Muconate Lactonizing
LuPra_RS05055	COG1534	Rna-binding protein
LuPra_RS05080	COG2345	Transcriptional regulator
LuPra_RS05090	COG0745	RESPONSE REGULATOR receiver
LuPra_RS05095	COG5002	protein histidine kinase activity
LuPra_RS05120	COG1555	photosystem II stabilization
LuPra_RS05130	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LuPra_RS05150	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
LuPra_RS05155	COG2211	Major facilitator Superfamily
LuPra_RS05165	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LuPra_RS05180	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
LuPra_RS05185	COG2133	pyrroloquinoline quinone binding
LuPra_RS05190	COG0673	inositol 2-dehydrogenase activity
LuPra_RS05200	COG1238	metal cluster binding
LuPra_RS05205	COG0531	amino acid
LuPra_RS05225	COG0438	transferase activity, transferring glycosyl groups
LuPra_RS05255	COG1477	protein flavinylation
LuPra_RS05270	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LuPra_RS05275	COG2133	pyrroloquinoline quinone binding
LuPra_RS05290	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
LuPra_RS05300	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
LuPra_RS05335	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LuPra_RS05345	COG1295	ribonuclease BN
LuPra_RS05365	COG1793	dna ligase
LuPra_RS05375	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LuPra_RS05390	COG2226	methyltransferase
LuPra_RS05405	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LuPra_RS05430	COG2084	Dehydrogenase
LuPra_RS05440	COG0823	Involved in the tonB-independent uptake of proteins
LuPra_RS05450	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LuPra_RS05455	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LuPra_RS05460	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LuPra_RS05465	COG3964	amidohydrolase
LuPra_RS05495	COG2815	serine threonine protein kinase
LuPra_RS05495	COG0515	serine threonine protein kinase
LuPra_RS05530	COG0515	serine threonine protein kinase
LuPra_RS05545	COG1402	creatininase
LuPra_RS05550	COG0745	RESPONSE REGULATOR receiver
LuPra_RS05570	COG2192	nodulation
LuPra_RS05590	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
LuPra_RS05600	COG0745	RESPONSE REGULATOR receiver
LuPra_RS05610	COG2311	Membrane
LuPra_RS05615	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LuPra_RS05620	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LuPra_RS05635	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LuPra_RS05645	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LuPra_RS05650	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LuPra_RS05655	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LuPra_RS05675	COG0640	Transcriptional regulator
LuPra_RS05705	COG0640	Transcriptional regulator
LuPra_RS05725	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LuPra_RS05750	COG1228	amidohydrolase
LuPra_RS05775	COG4941	Belongs to the sigma-70 factor family
LuPra_RS05785	COG2234	aminopeptidase activity
LuPra_RS05800	COG0438	transferase activity, transferring glycosyl groups
LuPra_RS05900	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
LuPra_RS05945	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LuPra_RS05970	COG2608	mercury ion transmembrane transporter activity
LuPra_RS05975	COG2217	Heavy metal translocating P-type atpase
LuPra_RS05980	COG1937	Protein conserved in bacteria
LuPra_RS06000	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LuPra_RS06005	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LuPra_RS06010	COG1902	pentaerythritol trinitrate reductase activity
LuPra_RS06045	COG0784	Response regulator, receiver
LuPra_RS06060	COG0513	Belongs to the DEAD box helicase family
LuPra_RS06095	COG0437	4 iron, 4 sulfur cluster binding
LuPra_RS06095	COG3064	Membrane
LuPra_RS06105	COG0584	glycerophosphoryl diester phosphodiesterase
LuPra_RS06115	COG4948	Mandelate Racemase Muconate Lactonizing
LuPra_RS06120	COG2195	Cleaves the N-terminal amino acid of tripeptides
LuPra_RS06135	COG2271	Major facilitator Superfamily
LuPra_RS06175	COG1606	tRNA processing
LuPra_RS06180	COG1691	(AIR) carboxylase
LuPra_RS06185	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
LuPra_RS06205	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LuPra_RS06210	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LuPra_RS06240	COG1872	DUF167
LuPra_RS06245	COG4771	TonB-dependent receptor
LuPra_RS06255	COG1595	DNA-templated transcription, initiation
LuPra_RS06280	COG2234	aminopeptidase activity
LuPra_RS06285	COG2204	response regulator
LuPra_RS06295	COG3852	Histidine kinase
LuPra_RS06315	COG1785	Belongs to the alkaline phosphatase family
LuPra_RS06320	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LuPra_RS06350	COG0745	RESPONSE REGULATOR receiver
LuPra_RS06355	COG2770	Histidine kinase
LuPra_RS06355	COG2208	phosphoserine phosphatase activity
LuPra_RS06510	COG2815	serine threonine protein kinase
LuPra_RS06510	COG0515	serine threonine protein kinase
LuPra_RS06520	COG0535	radical SAM domain protein
LuPra_RS06525	COG1216	Glycosyl transferase, family 2
LuPra_RS06530	COG2192	nodulation
LuPra_RS06550	COG0741	lytic transglycosylase activity
LuPra_RS06550	COG1388	LysM domain
LuPra_RS06575	COG0318	PFAM AMP-dependent synthetase and ligase
LuPra_RS06590	COG0251	oxidation-reduction process
LuPra_RS06605	COG0318	PFAM AMP-dependent synthetase and ligase
LuPra_RS06610	COG0006	proline dipeptidase activity
LuPra_RS06625	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LuPra_RS06635	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LuPra_RS06675	COG2172	sigma factor antagonist activity
LuPra_RS06680	COG2172	sigma factor antagonist activity
LuPra_RS06685	COG1295	ribonuclease BN
LuPra_RS06705	COG3685	Protein conserved in bacteria
LuPra_RS06725	COG3685	Protein conserved in bacteria
LuPra_RS06740	COG5002	protein histidine kinase activity
LuPra_RS06775	COG3104	oligopeptide transport
LuPra_RS06785	COG3550	peptidyl-serine autophosphorylation
LuPra_RS06810	COG2815	serine threonine protein kinase
LuPra_RS06810	COG0515	serine threonine protein kinase
LuPra_RS06840	COG0823	Involved in the tonB-independent uptake of proteins
LuPra_RS06845	COG3866	Pectate lyase
LuPra_RS06855	COG1695	Transcriptional regulator
LuPra_RS06860	COG0577	efflux transmembrane transporter activity
LuPra_RS06860	COG1136	(ABC) transporter
LuPra_RS06865	COG2204	response regulator
LuPra_RS06870	COG3119	arylsulfatase activity
LuPra_RS06875	COG0667	Aldo Keto reductase
LuPra_RS06880	COG0628	permease
LuPra_RS06900	COG0025	NhaP-type Na H and K H
LuPra_RS06935	COG1595	DNA-templated transcription, initiation
LuPra_RS06950	COG1028	Short-chain dehydrogenase reductase Sdr
LuPra_RS06990	COG2197	response regulator
LuPra_RS06995	COG4993	Dehydrogenase
LuPra_RS07005	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LuPra_RS07010	COG2261	transglycosylase associated protein
LuPra_RS07020	COG3285	dna ligase
LuPra_RS07020	COG1793	dna ligase
LuPra_RS07025	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
LuPra_RS07030	COG0861	Integral membrane protein TerC family
LuPra_RS07090	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LuPra_RS07165	COG0673	inositol 2-dehydrogenase activity
LuPra_RS07170	COG1404	Belongs to the peptidase S8 family
LuPra_RS07175	COG0346	lactoylglutathione lyase activity
LuPra_RS07180	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LuPra_RS07180	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LuPra_RS07185	COG1703	isobutyryl-CoA mutase activity
LuPra_RS07190	COG0673	inositol 2-dehydrogenase activity
LuPra_RS07210	COG1793	dna ligase
LuPra_RS07210	COG3285	dna ligase
LuPra_RS07225	COG2815	serine threonine protein kinase
LuPra_RS07225	COG0515	serine threonine protein kinase
LuPra_RS07230	COG2815	serine threonine protein kinase
LuPra_RS07230	COG0515	serine threonine protein kinase
LuPra_RS07270	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LuPra_RS07275	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LuPra_RS07290	COG1834	amidinotransferase
LuPra_RS07315	COG1028	Short-chain dehydrogenase reductase Sdr
LuPra_RS07335	COG1595	DNA-templated transcription, initiation
LuPra_RS07345	COG4771	TonB-dependent receptor
LuPra_RS07365	COG1366	Belongs to the anti-sigma-factor antagonist family
LuPra_RS07370	COG1366	Belongs to the anti-sigma-factor antagonist family
LuPra_RS07375	COG2172	sigma factor antagonist activity
LuPra_RS07385	COG2205	protein histidine kinase activity
LuPra_RS07390	COG2205	protein histidine kinase activity
LuPra_RS07400	COG1136	(ABC) transporter
LuPra_RS07400	COG0577	efflux transmembrane transporter activity
LuPra_RS07480	COG5564	TIM-barrel signal transduction protein
LuPra_RS07505	COG1648	precorrin-2 dehydrogenase activity
LuPra_RS07505	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LuPra_RS07510	COG0243	molybdopterin cofactor binding
LuPra_RS07515	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LuPra_RS07525	COG2223	nitrite transmembrane transporter activity
LuPra_RS07630	COG1136	(ABC) transporter
LuPra_RS07630	COG0577	efflux transmembrane transporter activity
LuPra_RS07690	COG0515	serine threonine protein kinase
LuPra_RS07755	COG0577	efflux transmembrane transporter activity
LuPra_RS07755	COG1136	(ABC) transporter
LuPra_RS07770	COG0577	efflux transmembrane transporter activity
LuPra_RS07775	COG1695	Transcriptional regulator
LuPra_RS07900	COG0724	RNA recognition motif
LuPra_RS07990	COG0464	growth
LuPra_RS08040	COG2205	protein histidine kinase activity
LuPra_RS08050	COG0667	Aldo Keto reductase
LuPra_RS08055	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LuPra_RS08060	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LuPra_RS08065	COG0581	inorganic phosphate transmembrane transporter activity
LuPra_RS08070	COG0573	inorganic phosphate transmembrane transporter activity
LuPra_RS08080	COG0704	Plays a role in the regulation of phosphate uptake
LuPra_RS08105	COG3842	ATPase activity
LuPra_RS08145	COG0330	HflC and HflK could
LuPra_RS08155	COG1595	DNA-templated transcription, initiation
LuPra_RS08160	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LuPra_RS08190	COG2815	serine threonine protein kinase
LuPra_RS08190	COG0515	serine threonine protein kinase
LuPra_RS08205	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
LuPra_RS08255	COG2133	pyrroloquinoline quinone binding
LuPra_RS08280	COG0745	RESPONSE REGULATOR receiver
LuPra_RS08290	COG3685	Protein conserved in bacteria
LuPra_RS08330	COG0784	Response regulator, receiver
LuPra_RS08330	COG2205	protein histidine kinase activity
LuPra_RS08400	COG0515	serine threonine protein kinase
LuPra_RS08400	COG2815	serine threonine protein kinase
LuPra_RS08405	COG3591	Belongs to the peptidase S1B family
LuPra_RS08415	COG2205	protein histidine kinase activity
LuPra_RS08445	COG3534	alpha-L-arabinofuranosidase
LuPra_RS08490	COG0823	Involved in the tonB-independent uptake of proteins
LuPra_RS08520	COG2815	serine threonine protein kinase
LuPra_RS08520	COG0515	serine threonine protein kinase
LuPra_RS08560	COG1063	alcohol dehydrogenase
LuPra_RS08620	COG3547	Transposase (IS116 IS110 IS902 family)
LuPra_RS08625	COG3547	Transposase (IS116 IS110 IS902 family)
LuPra_RS08675	COG0515	serine threonine protein kinase
LuPra_RS08675	COG2815	serine threonine protein kinase
LuPra_RS08710	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LuPra_RS08790	COG1335	isochorismatase
LuPra_RS08810	COG4974	Belongs to the 'phage' integrase family
LuPra_RS08825	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
LuPra_RS08840	COG2264	protein methyltransferase activity
LuPra_RS08845	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LuPra_RS08845	COG2205	protein histidine kinase activity
LuPra_RS08870	COG3254	rhamnose metabolic process
LuPra_RS08915	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LuPra_RS08920	COG2204	response regulator
LuPra_RS08925	COG2226	methyltransferase
LuPra_RS08945	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LuPra_RS08980	COG2815	serine threonine protein kinase
LuPra_RS08980	COG0515	serine threonine protein kinase
LuPra_RS08995	COG0673	inositol 2-dehydrogenase activity
LuPra_RS09005	COG1028	Short-chain dehydrogenase reductase Sdr
LuPra_RS09030	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LuPra_RS09035	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
LuPra_RS09085	COG1574	metal-dependent hydrolase with the TIM-barrel fold
LuPra_RS09105	COG2070	2-Nitropropane dioxygenase
LuPra_RS09120	COG1725	Transcriptional regulator
LuPra_RS09150	COG0277	FAD linked oxidase domain protein
LuPra_RS09160	COG4232	protein-disulfide reductase activity
LuPra_RS09170	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LuPra_RS09180	COG0745	RESPONSE REGULATOR receiver
LuPra_RS09210	COG0631	protein serine/threonine phosphatase activity
LuPra_RS09220	COG0772	Belongs to the SEDS family
LuPra_RS09235	COG1051	belongs to the nudix hydrolase family
LuPra_RS09255	COG1714	RDD family
LuPra_RS09285	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
LuPra_RS09310	COG3693	PFAM glycoside hydrolase, family 10
LuPra_RS09310	COG2382	esterase
LuPra_RS09315	COG5479	isomerase activity
LuPra_RS09315	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
LuPra_RS09330	COG2318	DinB family
LuPra_RS09340	COG1191	sigma factor activity
LuPra_RS09375	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LuPra_RS09475	COG0673	inositol 2-dehydrogenase activity
LuPra_RS09485	COG1028	Short-chain dehydrogenase reductase Sdr
LuPra_RS09495	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LuPra_RS09500	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LuPra_RS09535	COG2815	serine threonine protein kinase
LuPra_RS09535	COG0515	serine threonine protein kinase
LuPra_RS09570	COG0277	FAD linked oxidase domain protein
LuPra_RS09595	COG0432	Pfam Uncharacterised protein family UPF0047
LuPra_RS09605	COG1879	ABC-type sugar transport system periplasmic component
LuPra_RS09610	COG1129	ABC transporter
LuPra_RS09615	COG1172	Belongs to the binding-protein-dependent transport system permease family
LuPra_RS09625	COG4191	Histidine kinase
LuPra_RS09635	COG2823	Periplasmic or secreted lipoprotein
LuPra_RS09670	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LuPra_RS09720	COG0515	serine threonine protein kinase
LuPra_RS09740	COG3108	Peptidase M15
LuPra_RS09755	COG2226	methyltransferase
LuPra_RS09800	COG2205	protein histidine kinase activity
LuPra_RS09800	COG0784	Response regulator, receiver
LuPra_RS09805	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
LuPra_RS09810	COG0673	inositol 2-dehydrogenase activity
LuPra_RS09815	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LuPra_RS09825	COG1072	(Pantothenic acid kinase))
LuPra_RS09830	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LuPra_RS09835	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LuPra_RS09845	COG0860	N-Acetylmuramoyl-L-alanine amidase
LuPra_RS09850	COG0179	Fumarylacetoacetate (FAA) hydrolase
LuPra_RS09860	COG1070	Carbohydrate kinase
LuPra_RS09865	COG4952	isomerase
LuPra_RS09875	COG3347	Dehydrogenase
LuPra_RS09875	COG1028	Short-chain dehydrogenase reductase Sdr
LuPra_RS09880	COG0612	Peptidase, M16
LuPra_RS09890	COG1136	(ABC) transporter
LuPra_RS09890	COG0577	efflux transmembrane transporter activity
LuPra_RS09905	COG2814	Major facilitator Superfamily
LuPra_RS09935	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LuPra_RS09955	COG2132	Multicopper oxidase
LuPra_RS09985	COG4263	nitrous-oxide reductase activity
LuPra_RS10000	COG1131	(ABC) transporter
LuPra_RS10020	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LuPra_RS10020	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LuPra_RS10030	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LuPra_RS10040	COG0251	oxidation-reduction process
LuPra_RS10050	COG0251	oxidation-reduction process
LuPra_RS10060	COG1921	L-seryl-tRNASec selenium transferase activity
LuPra_RS10105	COG2132	Multicopper oxidase
LuPra_RS10110	COG2706	6-phosphogluconolactonase activity
LuPra_RS10115	COG2271	Major facilitator Superfamily
LuPra_RS10140	COG0110	maltose O-acetyltransferase activity
LuPra_RS10150	COG1902	pentaerythritol trinitrate reductase activity
LuPra_RS10155	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
LuPra_RS10160	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LuPra_RS10160	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LuPra_RS10160	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LuPra_RS10175	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
LuPra_RS10185	COG1752	Esterase of the alpha-beta hydrolase superfamily
LuPra_RS10190	COG0387	Pfam Sodium calcium exchanger
LuPra_RS10205	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LuPra_RS10210	COG0392	lysyltransferase activity
LuPra_RS10210	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LuPra_RS10225	COG0129	dihydroxy-acid dehydratase activity
LuPra_RS10230	COG0281	malic enzyme
LuPra_RS10275	COG0515	serine threonine protein kinase
LuPra_RS10295	COG1304	FMN binding
LuPra_RS10310	COG0673	inositol 2-dehydrogenase activity
LuPra_RS10355	COG2226	methyltransferase
LuPra_RS10360	COG2226	methyltransferase
LuPra_RS10370	COG0596	Alpha beta hydrolase
LuPra_RS10380	COG0617	tRNA 3'-terminal CCA addition
LuPra_RS10380	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LuPra_RS10380	COG0517	IMP dehydrogenase activity
LuPra_RS10405	COG2226	methyltransferase
LuPra_RS10420	COG0531	amino acid
LuPra_RS10435	COG2271	Major facilitator Superfamily
LuPra_RS10510	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LuPra_RS10515	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LuPra_RS10535	COG4555	ABC transporter
LuPra_RS10540	COG3250	beta-galactosidase activity
LuPra_RS10590	COG4948	Mandelate Racemase Muconate Lactonizing
LuPra_RS10600	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
LuPra_RS10610	COG0247	lactate metabolic process
LuPra_RS10620	COG0277	FAD linked oxidase domain protein
LuPra_RS10625	COG1620	l-lactate permease
LuPra_RS10630	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LuPra_RS10645	COG0673	inositol 2-dehydrogenase activity
LuPra_RS10655	COG0673	inositol 2-dehydrogenase activity
LuPra_RS10670	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LuPra_RS10685	COG0175	sulfate reduction
LuPra_RS10690	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LuPra_RS10695	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
LuPra_RS10700	COG4521	taurine ABC transporter
LuPra_RS10705	COG2515	1-aminocyclopropane-1-carboxylate deaminase
LuPra_RS10735	COG2815	serine threonine protein kinase
LuPra_RS10735	COG0515	serine threonine protein kinase
LuPra_RS10740	COG2815	serine threonine protein kinase
LuPra_RS10740	COG0515	serine threonine protein kinase
LuPra_RS10745	COG3118	belongs to the thioredoxin family
LuPra_RS10750	COG0154	amidase activity
LuPra_RS10755	COG2226	methyltransferase
LuPra_RS10790	COG1301	dicarboxylic acid transport
LuPra_RS10795	COG1968	undecaprenyl-diphosphatase activity
LuPra_RS10860	COG2080	2 iron, 2 sulfur cluster binding
LuPra_RS10875	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LuPra_RS10905	COG0673	inositol 2-dehydrogenase activity
LuPra_RS10925	COG2010	Cytochrome c
LuPra_RS10925	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LuPra_RS10955	COG0805	protein transport
LuPra_RS10960	COG0741	lytic transglycosylase activity
LuPra_RS10960	COG0739	heme binding
LuPra_RS10960	COG1196	nuclear chromosome segregation
LuPra_RS10980	COG3604	Transcriptional regulator
LuPra_RS10990	COG3604	Transcriptional regulator
LuPra_RS11050	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LuPra_RS11060	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LuPra_RS11075	COG1760	l-serine dehydratase
LuPra_RS11085	COG3064	Membrane
LuPra_RS11120	COG1538	Outer membrane efflux protein
LuPra_RS11135	COG0471	metal ion transport
LuPra_RS11140	COG2985	domain, Protein
LuPra_RS11145	COG0252	asparaginase activity
LuPra_RS11150	COG2202	Pas domain
LuPra_RS11150	COG2205	protein histidine kinase activity
LuPra_RS11170	COG0577	efflux transmembrane transporter activity
LuPra_RS11170	COG1136	(ABC) transporter
LuPra_RS11180	COG5002	protein histidine kinase activity
LuPra_RS11185	COG1858	cytochrome C peroxidase
LuPra_RS11195	COG0577	efflux transmembrane transporter activity
LuPra_RS11195	COG1136	(ABC) transporter
LuPra_RS11210	COG2205	protein histidine kinase activity
LuPra_RS11230	COG3179	chitinase
LuPra_RS11235	COG0673	inositol 2-dehydrogenase activity
LuPra_RS11240	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LuPra_RS11270	COG0577	efflux transmembrane transporter activity
LuPra_RS11285	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LuPra_RS11300	COG3648	Uricase
LuPra_RS11300	COG3195	allantoin biosynthetic process
LuPra_RS11305	COG3195	allantoin biosynthetic process
LuPra_RS11305	COG3648	Uricase
LuPra_RS11325	COG3459	Glycosyltransferase 36 associated
LuPra_RS11335	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LuPra_RS11380	COG0577	efflux transmembrane transporter activity
LuPra_RS11380	COG1136	(ABC) transporter
LuPra_RS11395	COG0628	permease
LuPra_RS11400	COG3710	Transcriptional regulator
LuPra_RS11425	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LuPra_RS11445	COG1404	Belongs to the peptidase S8 family
LuPra_RS11450	COG2234	aminopeptidase activity
LuPra_RS11495	COG0456	acetyltransferase
LuPra_RS11500	COG0288	reversible hydration of carbon dioxide
LuPra_RS11550	COG0154	amidase activity
LuPra_RS11560	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
LuPra_RS11585	COG3609	addiction module antidote protein, CC2985 family
LuPra_RS11605	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
LuPra_RS11640	COG1312	Catalyzes the dehydration of D-mannonate
LuPra_RS11665	COG0037	tRNA processing
LuPra_RS11665	COG0590	tRNA wobble adenosine to inosine editing
LuPra_RS11705	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LuPra_RS11715	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LuPra_RS11735	COG1917	Cupin 2, conserved barrel domain protein
LuPra_RS11735	COG4977	sequence-specific DNA binding
LuPra_RS11775	COG0823	Involved in the tonB-independent uptake of proteins
LuPra_RS11810	COG1233	COG1233 Phytoene dehydrogenase and related
LuPra_RS11845	COG1434	Gram-negative-bacterium-type cell wall biogenesis
LuPra_RS11865	COG0515	serine threonine protein kinase
LuPra_RS11905	COG2815	serine threonine protein kinase
LuPra_RS11905	COG0515	serine threonine protein kinase
LuPra_RS12070	COG1404	Belongs to the peptidase S8 family
LuPra_RS12080	COG3179	chitinase
LuPra_RS12100	COG4548	von Willebrand factor, type A
LuPra_RS12105	COG0714	Associated with various cellular activities
LuPra_RS12110	COG3256	nitric oxide reductase
LuPra_RS12115	COG2010	Cytochrome c
LuPra_RS12125	COG0515	serine threonine protein kinase
LuPra_RS12125	COG2815	serine threonine protein kinase
LuPra_RS12155	COG1454	alcohol dehydrogenase
LuPra_RS12160	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LuPra_RS12175	COG0404	The glycine cleavage system catalyzes the degradation of glycine
LuPra_RS12220	COG2382	esterase
LuPra_RS12245	COG0753	catalase activity
LuPra_RS12295	COG0515	serine threonine protein kinase
LuPra_RS12310	COG2197	response regulator
LuPra_RS12320	COG2031	fatty acid transporter
LuPra_RS12340	COG0702	epimerase
LuPra_RS12395	COG0515	serine threonine protein kinase
LuPra_RS12395	COG2815	serine threonine protein kinase
LuPra_RS12400	COG0515	serine threonine protein kinase
LuPra_RS12465	COG0823	Involved in the tonB-independent uptake of proteins
LuPra_RS12500	COG0515	serine threonine protein kinase
LuPra_RS12500	COG2815	serine threonine protein kinase
LuPra_RS12510	COG2010	Cytochrome c
LuPra_RS12510	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LuPra_RS12525	COG0596	Alpha beta hydrolase
LuPra_RS12530	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LuPra_RS12535	COG1228	amidohydrolase
LuPra_RS12540	COG2267	carboxylic ester hydrolase activity
LuPra_RS12560	COG0515	serine threonine protein kinase
LuPra_RS12575	COG3179	chitinase
LuPra_RS12580	COG1312	Catalyzes the dehydration of D-mannonate
LuPra_RS12605	COG0402	S-adenosylhomocysteine deaminase activity
LuPra_RS12615	COG1028	Short-chain dehydrogenase reductase Sdr
LuPra_RS12625	COG0308	aminopeptidase N
LuPra_RS12665	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LuPra_RS12710	COG0745	RESPONSE REGULATOR receiver
LuPra_RS12780	COG2304	oxidoreductase activity
LuPra_RS12800	COG2815	serine threonine protein kinase
LuPra_RS12800	COG0515	serine threonine protein kinase
LuPra_RS12805	COG2815	serine threonine protein kinase
LuPra_RS12805	COG0515	serine threonine protein kinase
LuPra_RS12840	COG0531	amino acid
LuPra_RS12865	COG3693	PFAM glycoside hydrolase, family 10
LuPra_RS12900	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LuPra_RS12930	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LuPra_RS12930	COG0515	serine threonine protein kinase
LuPra_RS12945	COG1288	antiporter activity
LuPra_RS12975	COG5002	protein histidine kinase activity
LuPra_RS12975	COG2205	protein histidine kinase activity
LuPra_RS12975	COG0784	Response regulator, receiver
LuPra_RS13070	COG0823	Involved in the tonB-independent uptake of proteins
LuPra_RS13075	COG0823	Involved in the tonB-independent uptake of proteins
LuPra_RS13080	COG0823	Involved in the tonB-independent uptake of proteins
LuPra_RS13135	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LuPra_RS13140	COG4948	Mandelate Racemase Muconate Lactonizing
LuPra_RS13165	COG3250	beta-galactosidase activity
LuPra_RS13170	COG1028	Short-chain dehydrogenase reductase Sdr
LuPra_RS13185	COG4948	Mandelate Racemase Muconate Lactonizing
LuPra_RS13190	COG2271	Major facilitator Superfamily
LuPra_RS13205	COG5642	Protein of unknown function (DUF2384)
LuPra_RS13225	COG1131	(ABC) transporter
LuPra_RS13240	COG0515	serine threonine protein kinase
LuPra_RS13240	COG2815	serine threonine protein kinase
LuPra_RS13270	COG0515	serine threonine protein kinase
LuPra_RS13270	COG2815	serine threonine protein kinase
LuPra_RS13280	COG0457	Tetratricopeptide repeat
LuPra_RS13280	COG3710	Transcriptional regulator
LuPra_RS13285	COG0673	inositol 2-dehydrogenase activity
LuPra_RS13300	COG0515	serine threonine protein kinase
LuPra_RS13335	COG1473	amidohydrolase
LuPra_RS13385	COG0776	regulation of translation
LuPra_RS13400	COG0657	acetylesterase activity
LuPra_RS13415	COG1335	isochorismatase
LuPra_RS13470	COG2815	serine threonine protein kinase
LuPra_RS13470	COG0515	serine threonine protein kinase
LuPra_RS13490	COG0745	RESPONSE REGULATOR receiver
LuPra_RS13500	COG1131	(ABC) transporter
LuPra_RS13525	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LuPra_RS13525	COG0515	serine threonine protein kinase
LuPra_RS13610	COG1595	DNA-templated transcription, initiation
LuPra_RS13615	COG0515	serine threonine protein kinase
LuPra_RS13635	COG0252	asparaginase activity
LuPra_RS13650	COG0515	serine threonine protein kinase
LuPra_RS13650	COG2815	serine threonine protein kinase
LuPra_RS13655	COG2233	PERMEase
LuPra_RS13665	COG0631	protein serine/threonine phosphatase activity
LuPra_RS13735	COG0515	serine threonine protein kinase
LuPra_RS13765	COG2815	serine threonine protein kinase
LuPra_RS13765	COG0515	serine threonine protein kinase
LuPra_RS13815	COG2002	toxin-antitoxin pair type II binding
LuPra_RS13860	COG0515	serine threonine protein kinase
LuPra_RS13890	COG0631	protein serine/threonine phosphatase activity
LuPra_RS13920	COG2815	serine threonine protein kinase
LuPra_RS13920	COG0515	serine threonine protein kinase
LuPra_RS13960	COG0515	serine threonine protein kinase
LuPra_RS13985	COG0644	oxidoreductase
LuPra_RS14010	COG2815	serine threonine protein kinase
LuPra_RS14010	COG0515	serine threonine protein kinase
LuPra_RS14020	COG0456	acetyltransferase
LuPra_RS14070	COG0823	Involved in the tonB-independent uptake of proteins
LuPra_RS14080	COG0823	Involved in the tonB-independent uptake of proteins
LuPra_RS14130	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LuPra_RS14160	COG1388	LysM domain
LuPra_RS14160	COG0741	lytic transglycosylase activity
LuPra_RS14190	COG1132	(ABC) transporter
LuPra_RS14195	COG1132	(ABC) transporter
LuPra_RS14205	COG2226	methyltransferase
LuPra_RS14220	COG1418	mRNA catabolic process
LuPra_RS14235	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
LuPra_RS14245	COG0072	phenylalanine-tRNA ligase activity
LuPra_RS14250	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LuPra_RS14255	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LuPra_RS14260	COG0291	Belongs to the bacterial ribosomal protein bL35 family
LuPra_RS14265	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LuPra_RS14270	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LuPra_RS14295	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LuPra_RS14300	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LuPra_RS14305	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
LuPra_RS14310	COG0142	geranyltranstransferase activity
LuPra_RS14315	COG1722	exodeoxyribonuclease VII activity
LuPra_RS14325	COG1692	metallophosphoesterase
LuPra_RS14340	COG0842	Transport permease protein
LuPra_RS14345	COG1131	(ABC) transporter
LuPra_RS14350	COG1131	(ABC) transporter
LuPra_RS14385	COG0154	amidase activity
LuPra_RS14390	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LuPra_RS14410	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LuPra_RS14415	COG0612	Peptidase, M16
LuPra_RS14425	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LuPra_RS14450	COG1070	Carbohydrate kinase
LuPra_RS14455	COG0657	acetylesterase activity
LuPra_RS14455	COG2755	lipolytic protein G-D-S-L family
LuPra_RS14490	COG1082	Xylose isomerase domain protein TIM barrel
LuPra_RS14495	COG2186	Transcriptional regulator
LuPra_RS14520	COG4948	Mandelate Racemase Muconate Lactonizing
LuPra_RS14525	COG3622	Belongs to the hyi family
LuPra_RS14550	COG0673	inositol 2-dehydrogenase activity
LuPra_RS14560	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LuPra_RS14565	COG0673	inositol 2-dehydrogenase activity
LuPra_RS14575	COG2211	Major facilitator Superfamily
LuPra_RS14600	COG1104	cysteine desulfurase activity
LuPra_RS14680	COG0745	RESPONSE REGULATOR receiver
LuPra_RS14685	COG5002	protein histidine kinase activity
LuPra_RS14700	COG2873	o-acetylhomoserine
LuPra_RS14705	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LuPra_RS14725	COG2835	tetraacyldisaccharide 4'-kinase activity
LuPra_RS14745	COG0318	PFAM AMP-dependent synthetase and ligase
LuPra_RS14755	COG0720	synthase
LuPra_RS14765	COG0166	Belongs to the GPI family
LuPra_RS14770	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LuPra_RS14775	COG0363	glucosamine-6-phosphate deaminase activity
LuPra_RS14790	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
LuPra_RS14795	COG3104	oligopeptide transport
LuPra_RS14810	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LuPra_RS14830	COG0477	Major facilitator Superfamily
LuPra_RS14855	COG4941	Belongs to the sigma-70 factor family
LuPra_RS14860	COG0577	efflux transmembrane transporter activity
LuPra_RS14860	COG1136	(ABC) transporter
LuPra_RS14865	COG1136	(ABC) transporter
LuPra_RS14865	COG0577	efflux transmembrane transporter activity
LuPra_RS14885	COG2818	Glycosylase
LuPra_RS14900	COG0366	Alpha amylase catalytic
LuPra_RS14910	COG0243	molybdopterin cofactor binding
LuPra_RS14915	COG1252	NADH dehydrogenase
LuPra_RS14955	COG0584	glycerophosphoryl diester phosphodiesterase
LuPra_RS14960	COG0513	Belongs to the DEAD box helicase family
LuPra_RS14965	COG0724	RNA recognition motif
LuPra_RS14990	COG0786	glutamate:sodium symporter activity
LuPra_RS14995	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LuPra_RS15030	COG1329	Transcriptional regulator
LuPra_RS15050	COG1297	OPT oligopeptide transporter protein
LuPra_RS15060	COG0315	cyclic pyranopterin monophosphate synthase activity
LuPra_RS15065	COG1022	Amp-dependent synthetase and ligase
LuPra_RS15075	COG0681	Belongs to the peptidase S26 family
LuPra_RS15080	COG3279	Response regulator of the LytR AlgR family
LuPra_RS15095	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LuPra_RS15095	COG0646	methionine synthase
LuPra_RS15110	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LuPra_RS15120	COG2020	methyltransferase activity
LuPra_RS15125	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LuPra_RS15130	COG0644	oxidoreductase
LuPra_RS15155	COG0714	Associated with various cellular activities
LuPra_RS15185	COG3119	arylsulfatase activity
LuPra_RS15205	COG0372	Belongs to the citrate synthase family
LuPra_RS15210	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
LuPra_RS15220	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LuPra_RS15225	COG0581	inorganic phosphate transmembrane transporter activity
LuPra_RS15230	COG0573	inorganic phosphate transmembrane transporter activity
LuPra_RS15235	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LuPra_RS15245	COG2062	phosphohistidine phosphatase, SixA
LuPra_RS15250	COG3710	Transcriptional regulator
LuPra_RS15260	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LuPra_RS15270	COG0306	phosphate transporter
LuPra_RS15290	COG1063	alcohol dehydrogenase
LuPra_RS15295	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LuPra_RS15300	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
LuPra_RS15310	COG2205	protein histidine kinase activity
LuPra_RS15320	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
LuPra_RS15325	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
LuPra_RS15335	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LuPra_RS15360	COG0671	phosphoesterase, PA-phosphatase related
LuPra_RS15370	COG0745	RESPONSE REGULATOR receiver
LuPra_RS15375	COG0671	phosphoesterase, PA-phosphatase related
LuPra_RS15385	COG3191	aminopeptidase activity
LuPra_RS15390	COG0628	permease
LuPra_RS15400	COG2226	methyltransferase
LuPra_RS15415	COG0367	asparagine synthase
LuPra_RS15420	COG0463	Glycosyl transferase, family 2
LuPra_RS15425	COG5002	protein histidine kinase activity
LuPra_RS15460	COG2363	Small membrane protein
LuPra_RS15470	COG0673	inositol 2-dehydrogenase activity
LuPra_RS15495	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
LuPra_RS15500	COG1063	alcohol dehydrogenase
LuPra_RS15510	COG1028	Short-chain dehydrogenase reductase Sdr
LuPra_RS15520	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LuPra_RS15525	COG2957	Belongs to the agmatine deiminase family
LuPra_RS15540	COG2133	pyrroloquinoline quinone binding
LuPra_RS15545	COG0129	dihydroxy-acid dehydratase activity
LuPra_RS15550	COG0673	inositol 2-dehydrogenase activity
LuPra_RS15570	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LuPra_RS15575	COG2032	superoxide dismutase activity
LuPra_RS15580	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LuPra_RS15600	COG0514	ATP-dependent DNA helicase (RecQ)
LuPra_RS15620	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LuPra_RS15625	COG1366	Belongs to the anti-sigma-factor antagonist family
LuPra_RS15635	COG2770	Histidine kinase
LuPra_RS15635	COG2208	phosphoserine phosphatase activity
LuPra_RS15640	COG1666	GTP binding
LuPra_RS15650	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LuPra_RS15665	COG2385	sporulation resulting in formation of a cellular spore
LuPra_RS15700	COG2373	Large extracellular alpha-helical protein
LuPra_RS15715	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LuPra_RS15720	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
LuPra_RS15750	COG0572	uridine kinase
LuPra_RS15775	COG0450	alkyl hydroperoxide reductase
LuPra_RS15800	COG1063	alcohol dehydrogenase
LuPra_RS15810	COG4948	Mandelate Racemase Muconate Lactonizing
LuPra_RS15840	COG0004	ammonium transporteR
LuPra_RS15860	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
LuPra_RS15875	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LuPra_RS15880	COG0440	acetolactate synthase activity
LuPra_RS15885	COG0028	Belongs to the TPP enzyme family
LuPra_RS15890	COG0129	dihydroxy-acid dehydratase activity
LuPra_RS15895	COG0077	Prephenate dehydratase
LuPra_RS15895	COG1605	Chorismate mutase
LuPra_RS15905	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LuPra_RS15910	COG0124	histidyl-tRNA synthetase
LuPra_RS15915	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LuPra_RS15925	COG1702	phosphate starvation-inducible protein PhoH
LuPra_RS15930	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LuPra_RS15935	COG1253	flavin adenine dinucleotide binding
LuPra_RS15940	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LuPra_RS15945	COG2239	Acts as a magnesium transporter
LuPra_RS15950	COG1381	Involved in DNA repair and RecF pathway recombination
LuPra_RS15955	COG0752	glycyl-tRNA synthetase alpha subunit
LuPra_RS15960	COG0751	glycine-tRNA ligase activity
LuPra_RS15965	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LuPra_RS15965	COG0574	Belongs to the PEP-utilizing enzyme family
LuPra_RS15970	COG0598	Magnesium transport protein CorA
LuPra_RS15975	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LuPra_RS15980	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LuPra_RS15985	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LuPra_RS15990	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LuPra_RS16015	COG0556	nucleotide-excision repair
LuPra_RS16020	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LuPra_RS16045	COG0546	phosphoglycolate phosphatase activity
LuPra_RS16050	COG1473	amidohydrolase
LuPra_RS16055	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LuPra_RS16065	COG0823	Involved in the tonB-independent uptake of proteins
LuPra_RS16070	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LuPra_RS16095	COG4566	intracellular signal transduction
LuPra_RS16125	COG1131	(ABC) transporter
LuPra_RS16150	COG0339	signal peptide processing
LuPra_RS16195	COG0582	viral genome integration into host DNA
LuPra_RS16230	COG3458	cephalosporin-C deacetylase activity
LuPra_RS16235	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LuPra_RS16240	COG0012	GTP binding
LuPra_RS16245	COG0784	Response regulator, receiver
LuPra_RS16245	COG2198	Histidine kinase
LuPra_RS16245	COG2205	protein histidine kinase activity
LuPra_RS16250	COG0402	S-adenosylhomocysteine deaminase activity
LuPra_RS16255	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
LuPra_RS16260	COG0698	ribose 5-phosphate isomerase
LuPra_RS16265	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LuPra_RS16270	COG3253	May function as heme-dependent peroxidase
LuPra_RS16285	COG0668	transmembrane transport
LuPra_RS16305	COG2814	Major facilitator Superfamily
LuPra_RS16320	COG0101	tRNA pseudouridine synthase activity
LuPra_RS16330	COG0564	pseudouridine synthase activity
LuPra_RS16335	COG1940	carbohydrate kinase activity
LuPra_RS16340	COG4175	Glycine betaine
LuPra_RS16345	COG4176	ABC-type proline glycine betaine transport system permease component
LuPra_RS16370	COG3191	aminopeptidase activity
LuPra_RS16395	COG3185	4-Hydroxyphenylpyruvate dioxygenase
LuPra_RS16410	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
LuPra_RS16475	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LuPra_RS16525	COG0438	transferase activity, transferring glycosyl groups
LuPra_RS16535	COG0438	transferase activity, transferring glycosyl groups
LuPra_RS16550	COG2192	nodulation
LuPra_RS16555	COG2192	nodulation
LuPra_RS16570	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LuPra_RS16575	COG0489	protein tyrosine kinase activity
LuPra_RS16580	COG3267	Type II secretory pathway component ExeA
LuPra_RS16580	COG3409	Peptidoglycan-binding domain 1 protein
LuPra_RS16600	COG2204	response regulator
LuPra_RS16610	COG1136	(ABC) transporter
LuPra_RS16620	COG0577	efflux transmembrane transporter activity
LuPra_RS16635	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
LuPra_RS16645	COG0667	Aldo Keto reductase
LuPra_RS16650	COG1760	l-serine dehydratase
LuPra_RS16680	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LuPra_RS16705	COG1131	(ABC) transporter
LuPra_RS16710	COG1725	Transcriptional regulator
LuPra_RS16870	COG1250	3-hydroxyacyl-CoA dehydrogenase
LuPra_RS16875	COG0183	Belongs to the thiolase family
LuPra_RS16885	COG0424	maF-like protein
LuPra_RS16890	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
LuPra_RS16895	COG1138	Cytochrome C-type biogenesis protein
LuPra_RS16915	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LuPra_RS16930	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LuPra_RS16935	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LuPra_RS16965	COG0463	Glycosyl transferase, family 2
LuPra_RS16970	COG0110	maltose O-acetyltransferase activity
LuPra_RS16975	COG0367	asparagine synthase
LuPra_RS16980	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LuPra_RS16985	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LuPra_RS16990	COG0823	Involved in the tonB-independent uptake of proteins
LuPra_RS17005	COG1073	alpha beta
LuPra_RS17015	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LuPra_RS17075	COG0438	transferase activity, transferring glycosyl groups
LuPra_RS17085	COG0037	tRNA processing
LuPra_RS17095	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LuPra_RS17100	COG0471	metal ion transport
LuPra_RS17110	COG2003	Belongs to the UPF0758 family
LuPra_RS17115	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LuPra_RS17115	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LuPra_RS17120	COG0084	hydrolase, TatD family'
LuPra_RS17125	COG0142	geranyltranstransferase activity
LuPra_RS17135	COG2204	response regulator
LuPra_RS17140	COG0484	heat shock protein binding
LuPra_RS17155	COG0531	amino acid
LuPra_RS17170	COG4302	ethanolamine ammonia-lyase activity
LuPra_RS17175	COG1555	photosystem II stabilization
LuPra_RS17210	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LuPra_RS17210	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LuPra_RS17215	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LuPra_RS17220	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LuPra_RS17220	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LuPra_RS17225	COG0802	atpase or kinase
LuPra_RS17240	COG1609	Transcriptional regulator
LuPra_RS17255	COG0517	IMP dehydrogenase activity
LuPra_RS17255	COG0516	GMP reductase activity
LuPra_RS17260	COG0653	protein targeting
LuPra_RS17265	COG0739	heme binding
LuPra_RS17280	COG1454	alcohol dehydrogenase
LuPra_RS17280	COG1012	belongs to the aldehyde dehydrogenase family
LuPra_RS17295	COG0741	lytic transglycosylase activity
LuPra_RS17295	COG1196	nuclear chromosome segregation
LuPra_RS17295	COG0739	heme binding
LuPra_RS17300	COG1459	type II secretion system
LuPra_RS17305	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LuPra_RS17345	COG0347	Belongs to the P(II) protein family
LuPra_RS17350	COG0004	ammonium transporteR
LuPra_RS17390	COG2971	BadF BadG BcrA BcrD
LuPra_RS17395	COG0363	glucosamine-6-phosphate deaminase activity
LuPra_RS17400	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LuPra_RS17405	COG0714	Associated with various cellular activities
LuPra_RS17475	COG4974	Belongs to the 'phage' integrase family
LuPra_RS17485	COG4651	solute:proton antiporter activity
LuPra_RS17485	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LuPra_RS17490	COG1475	DNA binding
LuPra_RS17495	COG1192	Involved in chromosome partitioning
LuPra_RS17505	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LuPra_RS17510	COG0497	DNA recombination
LuPra_RS17515	COG0811	peptide transport
LuPra_RS17520	COG0848	biopolymer transport protein
LuPra_RS17530	COG0823	Involved in the tonB-independent uptake of proteins
LuPra_RS17535	COG2885	chlorophyll binding
LuPra_RS17545	COG0629	single-stranded DNA binding
LuPra_RS17550	COG0667	Aldo Keto reductase
LuPra_RS17560	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LuPra_RS17570	COG1660	Displays ATPase and GTPase activities
LuPra_RS17575	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
LuPra_RS17585	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
LuPra_RS17590	COG1137	ATPase activity
LuPra_RS17600	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LuPra_RS17600	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
LuPra_RS17605	COG0825	malonyl-CoA metabolic process
LuPra_RS17625	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LuPra_RS17630	COG5000	phosphorelay sensor kinase activity
LuPra_RS17635	COG1183	phosphatidylcholine synthase activity
LuPra_RS17640	COG0688	phosphatidylethanolamine metabolic process
LuPra_RS17655	COG1214	PFAM Peptidase M22, glycoprotease
LuPra_RS17660	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LuPra_RS17670	COG0596	Alpha beta hydrolase
LuPra_RS17680	COG3321	synthase
LuPra_RS17680	COG1028	Short-chain dehydrogenase reductase Sdr
LuPra_RS17680	COG0604	alcohol dehydrogenase
LuPra_RS17685	COG0534	Mate efflux family protein
LuPra_RS17690	COG2515	1-aminocyclopropane-1-carboxylate deaminase
LuPra_RS17700	COG0545	Peptidyl-prolyl cis-trans isomerase
LuPra_RS17735	COG0804	urea catabolic process
LuPra_RS17745	COG1166	arginine decarboxylase activity
LuPra_RS17765	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LuPra_RS17790	COG0187	DNA topoisomerase II activity
LuPra_RS17825	COG0567	Dehydrogenase, E1 component
LuPra_RS17830	COG0508	dehydrogenase complex catalyzes the overall conversion of
LuPra_RS17845	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LuPra_RS17870	COG2610	gluconate transmembrane transporter activity
LuPra_RS17885	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
LuPra_RS17895	COG1410	methionine synthase
LuPra_RS17895	COG0646	methionine synthase
LuPra_RS17905	COG3279	Response regulator of the LytR AlgR family
LuPra_RS17910	COG3275	phosphorelay sensor kinase activity
LuPra_RS17935	COG1164	Oligoendopeptidase f
LuPra_RS17950	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
LuPra_RS17965	COG2967	ApaG domain
LuPra_RS17985	COG2198	Histidine kinase
LuPra_RS17985	COG0784	Response regulator, receiver
LuPra_RS17985	COG0643	Histidine kinase
LuPra_RS17995	COG1360	Flagellar Motor Protein
LuPra_RS18000	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LuPra_RS18005	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
LuPra_RS18005	COG2199	diguanylate cyclase activity
LuPra_RS18030	COG0297	glycogen (starch) synthase activity
LuPra_RS18035	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LuPra_RS18035	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LuPra_RS18055	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
LuPra_RS18060	COG1181	Belongs to the D-alanine--D-alanine ligase family
LuPra_RS18065	COG2089	acid synthase
LuPra_RS18080	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LuPra_RS18095	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LuPra_RS18105	COG1516	flagellar protein fliS
LuPra_RS18120	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
LuPra_RS18130	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LuPra_RS18135	COG1256	bacterial-type flagellum assembly
LuPra_RS18150	COG0739	heme binding
LuPra_RS18150	COG0741	lytic transglycosylase activity
LuPra_RS18150	COG1196	nuclear chromosome segregation
LuPra_RS18155	COG1706	bacterial-type flagellum-dependent cell motility
LuPra_RS18160	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
LuPra_RS18175	COG4786	Flagellar basal body rod
LuPra_RS18190	COG1776	CheC inhibitor of MCP methylation
LuPra_RS18190	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LuPra_RS18195	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LuPra_RS18200	COG1191	sigma factor activity
LuPra_RS18205	COG1419	protein localization to endoplasmic reticulum
LuPra_RS18210	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LuPra_RS18215	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LuPra_RS18220	COG1684	flagellar biosynthetic protein fliR
LuPra_RS18225	COG1987	bacterial-type flagellum assembly
LuPra_RS18260	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
LuPra_RS18270	COG1157	protein secretion by the type III secretion system
LuPra_RS18275	COG1317	bacterial-type flagellum organization
LuPra_RS18280	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LuPra_RS18295	COG1558	bacterial-type flagellum-dependent cell motility
LuPra_RS18300	COG1815	bacterial-type flagellum-dependent cell motility
LuPra_RS18305	COG2204	response regulator
LuPra_RS18320	COG0745	RESPONSE REGULATOR receiver
LuPra_RS18350	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LuPra_RS18355	COG1254	Belongs to the acylphosphatase family
LuPra_RS18370	COG5002	protein histidine kinase activity
LuPra_RS18390	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
LuPra_RS18395	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
LuPra_RS18405	COG1181	Belongs to the D-alanine--D-alanine ligase family
LuPra_RS18410	COG0861	Integral membrane protein TerC family
LuPra_RS18415	COG0789	Transcriptional regulator
LuPra_RS18420	COG0484	heat shock protein binding
LuPra_RS18425	COG0542	response to heat
LuPra_RS18430	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LuPra_RS18435	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LuPra_RS18440	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LuPra_RS18445	COG0277	FAD linked oxidase domain protein
LuPra_RS18455	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LuPra_RS18460	COG0742	ribosomal rna small subunit methyltransferase
LuPra_RS18465	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LuPra_RS18475	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LuPra_RS18510	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LuPra_RS18525	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LuPra_RS18535	COG0860	N-Acetylmuramoyl-L-alanine amidase
LuPra_RS18545	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LuPra_RS18555	COG0183	Belongs to the thiolase family
LuPra_RS18565	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LuPra_RS18575	COG0287	Prephenate dehydrogenase
LuPra_RS18580	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
LuPra_RS18590	COG0159	tryptophan synthase activity
LuPra_RS18595	COG0133	tryptophan synthase activity
LuPra_RS18600	COG0135	phosphoribosylanthranilate isomerase activity
LuPra_RS18605	COG0134	indole-3-glycerol-phosphate synthase activity
LuPra_RS18610	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LuPra_RS18615	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LuPra_RS18615	COG0512	Glutamine amidotransferase of anthranilate synthase
LuPra_RS18625	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LuPra_RS18650	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LuPra_RS18655	COG0601	transmembrane transport
LuPra_RS18660	COG3604	Transcriptional regulator
LuPra_RS18665	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LuPra_RS18670	COG0242	peptide deformylase activity
LuPra_RS18675	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LuPra_RS18690	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LuPra_RS18695	COG0824	Thioesterase
LuPra_RS18700	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LuPra_RS18710	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LuPra_RS18780	COG2205	protein histidine kinase activity
LuPra_RS18785	COG3237	CsbD-like
LuPra_RS18795	COG2249	NAD(P)H dehydrogenase (quinone) activity
LuPra_RS18810	COG0561	phosphatase activity
LuPra_RS18825	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LuPra_RS18835	COG2204	response regulator
LuPra_RS18895	COG0673	inositol 2-dehydrogenase activity
LuPra_RS18925	COG5002	protein histidine kinase activity
LuPra_RS18940	COG0582	viral genome integration into host DNA
LuPra_RS19015	COG1160	GTP binding
LuPra_RS19030	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LuPra_RS19035	COG1573	uracil-dna glycosylase
LuPra_RS19040	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LuPra_RS19045	COG1758	RNA polymerase activity
LuPra_RS19055	COG1561	YicC-like family, N-terminal region
LuPra_RS19060	COG1132	(ABC) transporter
LuPra_RS19065	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LuPra_RS19080	COG0438	transferase activity, transferring glycosyl groups
LuPra_RS19095	COG0438	transferase activity, transferring glycosyl groups
LuPra_RS19100	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LuPra_RS19105	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LuPra_RS19120	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LuPra_RS19130	COG2814	Major facilitator Superfamily
LuPra_RS19135	COG1960	acyl-CoA dehydrogenase activity
LuPra_RS19150	COG1104	cysteine desulfurase activity
LuPra_RS19155	COG0482	sulfurtransferase activity
LuPra_RS19160	COG0492	ferredoxin-NADP+ reductase activity
LuPra_RS19170	COG0297	glycogen (starch) synthase activity
LuPra_RS19175	COG1686	Belongs to the peptidase S11 family
LuPra_RS19195	COG0460	homoserine dehydrogenase
LuPra_RS19200	COG0083	homoserine kinase activity
LuPra_RS19205	COG0133	tryptophan synthase activity
LuPra_RS19230	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LuPra_RS19235	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LuPra_RS19265	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LuPra_RS19310	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
LuPra_RS19315	COG3590	peptidase
LuPra_RS19330	COG1028	Short-chain dehydrogenase reductase Sdr
LuPra_RS19335	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LuPra_RS19350	COG2010	Cytochrome c
LuPra_RS19350	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LuPra_RS19385	COG2442	InterPro IPR007367
LuPra_RS19440	COG2172	sigma factor antagonist activity
LuPra_RS19450	COG1295	ribonuclease BN
LuPra_RS19470	COG1196	nuclear chromosome segregation
LuPra_RS19470	COG3264	Mechanosensitive ion channel
LuPra_RS19500	COG1028	Short-chain dehydrogenase reductase Sdr
LuPra_RS19505	COG1335	isochorismatase
LuPra_RS19520	COG0514	ATP-dependent DNA helicase (RecQ)
LuPra_RS19525	COG0723	plastoquinol--plastocyanin reductase activity
LuPra_RS19525	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LuPra_RS19540	COG0300	oxidoreductase activity
LuPra_RS19545	COG2154	pterin-4-alpha-carbinolamine dehydratase
LuPra_RS19585	COG3119	arylsulfatase activity
LuPra_RS19655	COG3668	Plasmid stabilization system
LuPra_RS19685	COG1484	DNA-dependent DNA replication
LuPra_RS19725	COG0745	RESPONSE REGULATOR receiver
LuPra_RS19745	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
LuPra_RS19755	COG3279	Response regulator of the LytR AlgR family
LuPra_RS19760	COG3275	phosphorelay sensor kinase activity
LuPra_RS19800	COG1597	lipid kinase activity
LuPra_RS19850	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LuPra_RS19865	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
LuPra_RS19875	COG0577	efflux transmembrane transporter activity
LuPra_RS19875	COG1136	(ABC) transporter
LuPra_RS19880	COG1136	(ABC) transporter
LuPra_RS19880	COG0577	efflux transmembrane transporter activity
LuPra_RS19885	COG1136	(ABC) transporter
LuPra_RS19915	COG0561	phosphatase activity
LuPra_RS19930	COG1131	(ABC) transporter
LuPra_RS19945	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LuPra_RS19950	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LuPra_RS19955	COG3485	protocatechuate 3,4-dioxygenase
LuPra_RS19960	COG3485	protocatechuate 3,4-dioxygenase
LuPra_RS19965	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LuPra_RS19970	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LuPra_RS19975	COG1414	Transcriptional regulator
LuPra_RS19980	COG0183	Belongs to the thiolase family
LuPra_RS20005	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LuPra_RS20015	COG2271	Major facilitator Superfamily
LuPra_RS20020	COG0154	amidase activity
LuPra_RS20065	COG1064	alcohol dehydrogenase
LuPra_RS20070	COG2207	Transcriptional regulator
LuPra_RS20085	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LuPra_RS20110	COG0492	ferredoxin-NADP+ reductase activity
LuPra_RS20120	COG1595	DNA-templated transcription, initiation
LuPra_RS20125	COG2226	methyltransferase
LuPra_RS20135	COG0798	PFAM Bile acid sodium symporter
LuPra_RS20185	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LuPra_RS20195	COG0571	ribonuclease III activity
LuPra_RS20205	COG0626	cystathionine gamma-synthase activity
LuPra_RS20210	COG1324	tolerance protein
LuPra_RS20215	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
LuPra_RS20230	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
LuPra_RS20245	COG3710	Transcriptional regulator
LuPra_RS20295	COG0644	oxidoreductase
LuPra_RS20340	COG0753	catalase activity
LuPra_RS20380	COG0753	catalase activity
LuPra_RS20425	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LuPra_RS20430	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LuPra_RS20450	COG2226	methyltransferase
LuPra_RS20470	COG0493	'glutamate synthase
LuPra_RS20475	COG0674	pyruvate-flavodoxin oxidoreductase activity
LuPra_RS20475	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
LuPra_RS20475	COG1013	pyruvate-flavodoxin oxidoreductase activity
LuPra_RS20475	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
LuPra_RS20490	COG2353	YceI-like domain
LuPra_RS20495	COG1136	(ABC) transporter
LuPra_RS20495	COG0577	efflux transmembrane transporter activity
LuPra_RS20505	COG1028	Short-chain dehydrogenase reductase Sdr
LuPra_RS20545	COG0009	L-threonylcarbamoyladenylate synthase
LuPra_RS20590	COG3033	Beta-eliminating lyase
LuPra_RS20595	COG0488	(ABC) transporter
LuPra_RS20600	COG2205	protein histidine kinase activity
LuPra_RS20600	COG0784	Response regulator, receiver
LuPra_RS20615	COG3291	Pkd domain containing protein
LuPra_RS20635	COG0673	inositol 2-dehydrogenase activity
LuPra_RS20650	COG1028	Short-chain dehydrogenase reductase Sdr
LuPra_RS20660	COG3119	arylsulfatase activity
LuPra_RS20685	COG0717	Belongs to the dCTP deaminase family
LuPra_RS20695	COG0105	UTP biosynthetic process
LuPra_RS20705	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
LuPra_RS20705	COG0674	pyruvate-flavodoxin oxidoreductase activity
LuPra_RS20710	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LuPra_RS20715	COG0045	succinate-CoA ligase (ADP-forming) activity
LuPra_RS20730	COG1053	succinate dehydrogenase
LuPra_RS20745	COG0538	isocitrate dehydrogenase activity
LuPra_RS20755	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
LuPra_RS20760	COG0504	CTP synthase activity
LuPra_RS20765	COG2877	3-deoxy-8-phosphooctulonate synthase activity
LuPra_RS20770	COG0517	IMP dehydrogenase activity
LuPra_RS20770	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LuPra_RS20775	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
LuPra_RS20780	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
LuPra_RS20785	COG0237	dephospho-CoA kinase activity
LuPra_RS20790	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LuPra_RS20795	COG0531	amino acid
LuPra_RS20800	COG0352	thiamine-phosphate diphosphorylase activity
LuPra_RS20805	COG0439	Biotin carboxylase
LuPra_RS20810	COG0511	ligase activity, forming carbon-carbon bonds
LuPra_RS20815	COG0006	proline dipeptidase activity
LuPra_RS20860	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LuPra_RS20865	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LuPra_RS20870	COG0052	Belongs to the universal ribosomal protein uS2 family
LuPra_RS20875	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LuPra_RS20880	COG0528	UMP kinase activity
LuPra_RS20885	COG0233	cytoplasmic translational termination
LuPra_RS20890	COG0252	asparaginase activity
LuPra_RS20895	COG0205	6-phosphofructokinase activity
LuPra_RS20925	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LuPra_RS20925	COG1796	DNA polymerase
LuPra_RS20930	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
LuPra_RS20935	COG4964	Belongs to the GSP D family
LuPra_RS20940	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LuPra_RS20945	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LuPra_RS20950	COG1984	allophanate hydrolase subunit 2
LuPra_RS20955	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
LuPra_RS20960	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LuPra_RS20965	COG1619	proteins homologs of microcin C7 resistance protein MccF
LuPra_RS20970	COG1472	Belongs to the glycosyl hydrolase 3 family
LuPra_RS20975	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LuPra_RS20975	COG1796	DNA polymerase
LuPra_RS20995	COG0352	thiamine-phosphate diphosphorylase activity
LuPra_RS21010	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LuPra_RS21015	COG0335	large ribosomal subunit rRNA binding
LuPra_RS21020	COG0336	Belongs to the RNA methyltransferase TrmD family
LuPra_RS21025	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LuPra_RS21030	COG1837	Belongs to the UPF0109 family
LuPra_RS21035	COG0228	four-way junction DNA binding
LuPra_RS21040	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LuPra_RS21050	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LuPra_RS21050	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LuPra_RS21060	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LuPra_RS21060	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LuPra_RS21065	COG0552	protein localization to endoplasmic reticulum
LuPra_RS21070	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LuPra_RS21075	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
LuPra_RS21080	COG1546	Belongs to the CinA family
LuPra_RS21080	COG1058	Belongs to the CinA family
LuPra_RS21085	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LuPra_RS21095	COG2204	response regulator
LuPra_RS21100	COG5000	phosphorelay sensor kinase activity
LuPra_RS21110	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LuPra_RS21140	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LuPra_RS21145	COG0459	protein refolding
LuPra_RS21160	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LuPra_RS21170	COG0557	exoribonuclease II activity
LuPra_RS21200	COG2379	hydroxypyruvate reductase
LuPra_RS21215	COG2884	Cell division ATP-binding protein ftsE
LuPra_RS21240	COG3547	Transposase (IS116 IS110 IS902 family)
LuPra_RS21255	COG1595	DNA-templated transcription, initiation
LuPra_RS21265	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LuPra_RS21290	COG2815	serine threonine protein kinase
LuPra_RS21290	COG0515	serine threonine protein kinase
LuPra_RS21305	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LuPra_RS21305	COG0116	Belongs to the methyltransferase superfamily
LuPra_RS21315	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LuPra_RS21325	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LuPra_RS21335	COG1136	(ABC) transporter
LuPra_RS21365	COG2986	histidine ammonia-lyase
LuPra_RS21375	COG1970	mechanosensitive ion channel activity
LuPra_RS21400	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LuPra_RS21445	COG1331	Highly conserved protein containing a thioredoxin domain
LuPra_RS21460	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LuPra_RS21470	COG1959	2 iron, 2 sulfur cluster binding
LuPra_RS21470	COG1295	ribonuclease BN
LuPra_RS21485	COG2204	response regulator
LuPra_RS21490	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LuPra_RS21495	COG1024	Enoyl-CoA hydratase
LuPra_RS21505	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LuPra_RS21525	COG2815	serine threonine protein kinase
LuPra_RS21525	COG0515	serine threonine protein kinase
LuPra_RS21530	COG4774	siderophore transport
LuPra_RS21535	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LuPra_RS21545	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
LuPra_RS21550	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
LuPra_RS21570	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LuPra_RS21580	COG0024	Methionine aminopeptidase
LuPra_RS21585	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LuPra_RS21590	COG1028	Short-chain dehydrogenase reductase Sdr
LuPra_RS21595	COG0506	proline dehydrogenase activity
LuPra_RS21605	COG0673	inositol 2-dehydrogenase activity
LuPra_RS21630	COG0673	inositol 2-dehydrogenase activity
LuPra_RS21675	COG1404	Belongs to the peptidase S8 family
LuPra_RS21695	COG0583	DNA-binding transcription factor activity
LuPra_RS21700	COG0668	transmembrane transport
LuPra_RS21715	COG0515	serine threonine protein kinase
LuPra_RS21715	COG2815	serine threonine protein kinase
LuPra_RS21770	COG0792	nuclease activity
LuPra_RS21800	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LuPra_RS21805	COG0215	cysteine-tRNA ligase activity
LuPra_RS21820	COG1234	tRNA 3'-trailer cleavage
LuPra_RS21830	COG3956	TIGRFAM MazG family protein
LuPra_RS21840	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LuPra_RS21845	COG0505	Belongs to the CarA family
LuPra_RS21855	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
LuPra_RS21860	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
LuPra_RS21865	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LuPra_RS21870	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
LuPra_RS21870	COG3608	succinylglutamate desuccinylase aspartoacylase
LuPra_RS21880	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LuPra_RS21885	COG0402	S-adenosylhomocysteine deaminase activity
LuPra_RS21890	COG1420	regulation of RNA biosynthetic process
LuPra_RS21895	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LuPra_RS21900	COG0484	heat shock protein binding
LuPra_RS21905	COG2264	protein methyltransferase activity
LuPra_RS21910	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LuPra_RS21920	COG0673	inositol 2-dehydrogenase activity
LuPra_RS21925	COG0673	inositol 2-dehydrogenase activity
LuPra_RS21950	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LuPra_RS21955	COG0739	heme binding
LuPra_RS21955	COG0741	lytic transglycosylase activity
LuPra_RS21955	COG1196	nuclear chromosome segregation
LuPra_RS21965	COG1950	PFAM Membrane protein of
LuPra_RS21980	COG0268	Binds directly to 16S ribosomal RNA
LuPra_RS21995	COG0495	leucyl-tRNA aminoacylation
LuPra_RS22000	COG3250	beta-galactosidase activity
LuPra_RS22040	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
LuPra_RS22050	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LuPra_RS22055	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LuPra_RS22060	COG1028	Short-chain dehydrogenase reductase Sdr
LuPra_RS22070	COG0416	fatty acid biosynthetic process
LuPra_RS22075	COG0333	Belongs to the bacterial ribosomal protein bL32 family
LuPra_RS22085	COG0232	Belongs to the dGTPase family. Type 2 subfamily
LuPra_RS22090	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
LuPra_RS22095	COG1923	regulation of RNA biosynthetic process
LuPra_RS22100	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LuPra_RS22110	COG2226	methyltransferase
LuPra_RS22125	COG0402	S-adenosylhomocysteine deaminase activity
LuPra_RS22130	COG0577	efflux transmembrane transporter activity
LuPra_RS22140	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
LuPra_RS22150	COG0673	inositol 2-dehydrogenase activity
LuPra_RS22160	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LuPra_RS22170	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LuPra_RS22175	COG0542	response to heat
LuPra_RS22185	COG4591	ABC-type transport system involved in lipoprotein release permease component
LuPra_RS22195	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LuPra_RS22200	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LuPra_RS22205	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
LuPra_RS22210	COG1024	Enoyl-CoA hydratase
LuPra_RS22230	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LuPra_RS22235	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
LuPra_RS22245	COG1960	acyl-CoA dehydrogenase activity
LuPra_RS22270	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LuPra_RS22280	COG0789	Transcriptional regulator
LuPra_RS22285	COG0484	heat shock protein binding
LuPra_RS22290	COG0443	Heat shock 70 kDa protein
LuPra_RS22300	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
LuPra_RS22310	COG0815	Transfers the fatty acyl group on membrane lipoproteins
LuPra_RS22330	COG0746	molybdenum cofactor guanylyltransferase activity
LuPra_RS22335	COG0018	arginyl-trna synthetase
LuPra_RS22340	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
LuPra_RS22350	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LuPra_RS22360	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
LuPra_RS22360	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
LuPra_RS22370	COG0525	valine-tRNA ligase activity
LuPra_RS22385	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LuPra_RS22390	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LuPra_RS22390	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LuPra_RS22400	COG1960	acyl-CoA dehydrogenase activity
LuPra_RS22440	COG2208	phosphoserine phosphatase activity
LuPra_RS22440	COG2770	Histidine kinase
LuPra_RS22450	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LuPra_RS22460	COG1960	acyl-CoA dehydrogenase activity
LuPra_RS22475	COG0539	negative regulation of cytoplasmic translation
LuPra_RS22475	COG2183	response to ionizing radiation
LuPra_RS22500	COG1187	pseudouridine synthase activity
LuPra_RS22505	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LuPra_RS22515	COG0180	Tryptophanyl-tRNA synthetase
LuPra_RS22520	COG0322	excinuclease ABC activity
LuPra_RS22525	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LuPra_RS22545	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LuPra_RS22555	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LuPra_RS22560	COG2094	Belongs to the DNA glycosylase MPG family
LuPra_RS22570	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LuPra_RS22580	COG2271	Major facilitator Superfamily
LuPra_RS22600	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
LuPra_RS22700	COG1028	Short-chain dehydrogenase reductase Sdr
LuPra_RS22725	COG0577	efflux transmembrane transporter activity
LuPra_RS22725	COG1136	(ABC) transporter
LuPra_RS22740	COG3693	PFAM glycoside hydrolase, family 10
LuPra_RS22740	COG2382	esterase
LuPra_RS22760	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LuPra_RS22765	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LuPra_RS22780	COG0673	inositol 2-dehydrogenase activity
LuPra_RS22785	COG0488	(ABC) transporter
LuPra_RS22845	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LuPra_RS22855	COG4251	negative regulation of phosphorylation
LuPra_RS22860	COG3540	Alkaline phosphatase
LuPra_RS22865	COG1482	cell wall glycoprotein biosynthetic process
LuPra_RS22875	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LuPra_RS22885	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LuPra_RS22895	COG0756	dUTP diphosphatase activity
LuPra_RS22905	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LuPra_RS22925	COG1181	Belongs to the D-alanine--D-alanine ligase family
LuPra_RS22935	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LuPra_RS22945	COG1136	(ABC) transporter
LuPra_RS22945	COG0577	efflux transmembrane transporter activity
LuPra_RS22960	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LuPra_RS22965	COG2186	Transcriptional regulator
LuPra_RS22975	COG0488	(ABC) transporter
LuPra_RS22980	COG2183	response to ionizing radiation
LuPra_RS22985	COG0488	(ABC) transporter
LuPra_RS23000	COG0400	carboxylic ester hydrolase activity
LuPra_RS23005	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LuPra_RS23015	COG1132	(ABC) transporter
LuPra_RS23060	COG1678	Uncharacterized ACR, COG1678
LuPra_RS23065	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LuPra_RS23075	COG1172	Belongs to the binding-protein-dependent transport system permease family
LuPra_RS23080	COG1129	ABC transporter
LuPra_RS23100	COG1172	Belongs to the binding-protein-dependent transport system permease family
LuPra_RS23105	COG1129	ABC transporter
LuPra_RS23110	COG1879	ABC-type sugar transport system periplasmic component
LuPra_RS23115	COG1063	alcohol dehydrogenase
LuPra_RS23120	COG2721	sulfolactate sulfo-lyase activity
LuPra_RS23130	COG0739	heme binding
LuPra_RS23130	COG1196	nuclear chromosome segregation
LuPra_RS23130	COG0741	lytic transglycosylase activity
LuPra_RS23150	COG0673	inositol 2-dehydrogenase activity
LuPra_RS23155	COG0673	inositol 2-dehydrogenase activity
LuPra_RS23160	COG1902	pentaerythritol trinitrate reductase activity
LuPra_RS23160	COG0446	pyridine nucleotide-disulphide oxidoreductase
LuPra_RS23165	COG2271	Major facilitator Superfamily
LuPra_RS23175	COG0391	Required for morphogenesis under gluconeogenic growth conditions
LuPra_RS23195	COG1704	LemA family
LuPra_RS23280	COG1607	acyl-coa hydrolase
LuPra_RS23290	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
LuPra_RS23315	COG3844	kynureninase activity
LuPra_RS23325	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LuPra_RS23330	COG1573	uracil-dna glycosylase
LuPra_RS23335	COG0531	amino acid
LuPra_RS23340	COG3710	Transcriptional regulator
LuPra_RS23350	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LuPra_RS23365	COG1881	PFAM PEBP family protein
LuPra_RS23370	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LuPra_RS23375	COG0508	dehydrogenase complex catalyzes the overall conversion of
LuPra_RS23445	COG3118	belongs to the thioredoxin family
LuPra_RS23470	COG0531	amino acid
LuPra_RS23495	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LuPra_RS23505	COG0247	lactate metabolic process
LuPra_RS23510	COG1139	Iron-sulfur cluster binding protein
LuPra_RS23515	COG1556	Lactate utilization protein
LuPra_RS23550	COG3485	protocatechuate 3,4-dioxygenase
LuPra_RS23585	COG2234	aminopeptidase activity
LuPra_RS23620	COG1131	(ABC) transporter
LuPra_RS23630	COG0531	amino acid
LuPra_RS23635	COG1056	cytidyltransferase-related domain
LuPra_RS23635	COG1051	belongs to the nudix hydrolase family
LuPra_RS23640	COG2205	protein histidine kinase activity
LuPra_RS23660	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LuPra_RS23665	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
LuPra_RS23675	COG0295	cytidine deaminase activity
LuPra_RS23680	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
LuPra_RS23690	COG1228	amidohydrolase
LuPra_RS23695	COG0673	inositol 2-dehydrogenase activity
LuPra_RS23725	COG1595	DNA-templated transcription, initiation
LuPra_RS23765	COG0772	Belongs to the SEDS family
LuPra_RS23770	COG0768	penicillin binding
LuPra_RS23795	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LuPra_RS23800	COG0616	signal peptide processing
LuPra_RS23830	COG1446	asparaginase
LuPra_RS23835	COG0058	SHG alpha-glucan phosphorylase activity
LuPra_RS23850	COG0492	ferredoxin-NADP+ reductase activity
LuPra_RS23855	COG4191	Histidine kinase
LuPra_RS23890	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LuPra_RS23900	COG1082	Xylose isomerase domain protein TIM barrel
LuPra_RS23905	COG0017	Asparaginyl-tRNA synthetase
LuPra_RS23910	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LuPra_RS23920	COG0195	Participates in both transcription termination and antitermination
LuPra_RS23925	COG3266	domain, Protein
LuPra_RS23925	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LuPra_RS23930	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LuPra_RS23945	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LuPra_RS23950	COG1185	polyribonucleotide nucleotidyltransferase activity
LuPra_RS23970	COG1196	nuclear chromosome segregation
LuPra_RS23975	COG0793	Belongs to the peptidase S41A family
LuPra_RS23980	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LuPra_RS23985	COG0805	protein transport
LuPra_RS23990	COG2885	chlorophyll binding
LuPra_RS24005	COG0442	prolyl-tRNA aminoacylation
LuPra_RS24010	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
LuPra_RS24015	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LuPra_RS24020	COG2204	response regulator
LuPra_RS24050	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
LuPra_RS24065	COG1131	(ABC) transporter
LuPra_RS24075	COG2165	general secretion pathway protein
LuPra_RS24080	COG2165	general secretion pathway protein
LuPra_RS24090	COG5002	protein histidine kinase activity
LuPra_RS24095	COG1459	type II secretion system
LuPra_RS24105	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LuPra_RS24125	COG0577	efflux transmembrane transporter activity
LuPra_RS24125	COG1136	(ABC) transporter
LuPra_RS24130	COG1136	(ABC) transporter
LuPra_RS24130	COG0577	efflux transmembrane transporter activity
LuPra_RS24135	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LuPra_RS24155	COG0203	ribosomal protein L17
LuPra_RS24160	COG0202	RNA polymerase activity
LuPra_RS24165	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LuPra_RS24170	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LuPra_RS24180	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LuPra_RS24185	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LuPra_RS24190	COG0024	Methionine aminopeptidase
LuPra_RS24200	COG0201	protein transport
LuPra_RS24205	COG0200	Binds to the 23S rRNA
LuPra_RS24210	COG1841	ribosomal large subunit assembly
LuPra_RS24215	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LuPra_RS24220	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LuPra_RS24225	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LuPra_RS24230	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LuPra_RS24235	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LuPra_RS24240	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LuPra_RS24250	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LuPra_RS24255	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LuPra_RS24260	COG0255	Belongs to the universal ribosomal protein uL29 family
LuPra_RS24265	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LuPra_RS24270	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LuPra_RS24280	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LuPra_RS24285	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LuPra_RS24290	COG0089	rRNA binding
LuPra_RS24295	COG0088	Forms part of the polypeptide exit tunnel
LuPra_RS24300	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LuPra_RS24305	COG0051	transcription antitermination factor activity, RNA binding
LuPra_RS24310	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LuPra_RS24315	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LuPra_RS24320	COG0049	tRNA binding
LuPra_RS24325	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LuPra_RS24330	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LuPra_RS24340	COG0612	Peptidase, M16
LuPra_RS24350	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LuPra_RS24355	COG0085	RNA polymerase activity
LuPra_RS24360	COG0222	ribosome binding
LuPra_RS24365	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LuPra_RS24370	COG0081	regulation of translation
LuPra_RS24375	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LuPra_RS24395	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LuPra_RS24400	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LuPra_RS24425	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LuPra_RS24430	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LuPra_RS24435	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
LuPra_RS24435	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
LuPra_RS24455	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LuPra_RS24465	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LuPra_RS24470	COG0305	Participates in initiation and elongation during chromosome replication
LuPra_RS24475	COG0359	binds to the 23S rRNA
LuPra_RS24480	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LuPra_RS24485	COG0360	Binds together with S18 to 16S ribosomal RNA
LuPra_RS24490	COG0193	aminoacyl-tRNA hydrolase activity
LuPra_RS24500	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LuPra_RS24510	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LuPra_RS24535	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
LuPra_RS24545	COG1278	Cold shock
LuPra_RS24560	COG1921	L-seryl-tRNASec selenium transferase activity
LuPra_RS24585	COG1007	ATP synthesis coupled electron transport
LuPra_RS24595	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LuPra_RS24600	COG0713	ATP synthesis coupled electron transport
LuPra_RS24605	COG0839	Belongs to the complex I subunit 6 family
LuPra_RS24610	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
LuPra_RS24625	COG0649	NAD binding
LuPra_RS24630	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LuPra_RS24635	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LuPra_RS24640	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LuPra_RS24645	COG0438	transferase activity, transferring glycosyl groups
LuPra_RS24660	COG2022	thiamine diphosphate biosynthetic process
LuPra_RS24675	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LuPra_RS24685	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LuPra_RS24745	COG1086	Polysaccharide biosynthesis protein
LuPra_RS24760	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LuPra_RS24765	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LuPra_RS24770	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LuPra_RS24775	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
LuPra_RS24800	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LuPra_RS24830	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LuPra_RS24860	COG1301	dicarboxylic acid transport
LuPra_RS24880	COG1069	ribulokinase activity
LuPra_RS24900	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LuPra_RS24945	COG3181	Tripartite tricarboxylate transporter family receptor
LuPra_RS24965	COG1414	Transcriptional regulator
LuPra_RS24985	COG1215	transferase activity, transferring glycosyl groups
LuPra_RS25010	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LuPra_RS25015	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LuPra_RS25025	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LuPra_RS25030	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
LuPra_RS25035	COG1774	PSP1 C-terminal conserved region
LuPra_RS25040	COG0470	DNA polymerase III
LuPra_RS25045	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
LuPra_RS25095	COG2070	2-Nitropropane dioxygenase
LuPra_RS25120	COG0859	PFAM glycosyl transferase family 9
LuPra_RS25125	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
LuPra_RS25125	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
LuPra_RS25130	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
LuPra_RS25130	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
LuPra_RS25135	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LuPra_RS25160	COG1519	Transferase
LuPra_RS25165	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LuPra_RS25170	COG0126	phosphoglycerate kinase activity
LuPra_RS25175	COG0149	triose-phosphate isomerase activity
LuPra_RS25235	COG2197	response regulator
LuPra_RS25240	COG4585	Histidine kinase
LuPra_RS25255	COG1295	ribonuclease BN
LuPra_RS25260	COG2172	sigma factor antagonist activity
LuPra_RS25300	COG0673	inositol 2-dehydrogenase activity
LuPra_RS25330	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
LuPra_RS25335	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
LuPra_RS25345	COG1090	epimerase
LuPra_RS25355	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LuPra_RS25385	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LuPra_RS25400	COG3263	regulation of cellular component size
LuPra_RS25405	COG4942	peptidase
LuPra_RS25420	COG4999	Histidine kinase
LuPra_RS25420	COG2205	protein histidine kinase activity
LuPra_RS25420	COG3437	response regulator, receiver
LuPra_RS25420	COG3850	Histidine kinase
LuPra_RS25470	COG2815	serine threonine protein kinase
LuPra_RS25470	COG0515	serine threonine protein kinase
LuPra_RS25480	COG2815	serine threonine protein kinase
LuPra_RS25480	COG0515	serine threonine protein kinase
LuPra_RS25610	COG3693	PFAM glycoside hydrolase, family 10
LuPra_RS25610	COG3507	Belongs to the glycosyl hydrolase 43 family
LuPra_RS25610	COG2382	esterase
LuPra_RS25615	COG1063	alcohol dehydrogenase
LuPra_RS25635	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
LuPra_RS25640	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LuPra_RS25705	COG1295	ribonuclease BN
LuPra_RS25710	COG0628	permease
LuPra_RS25745	COG0793	Belongs to the peptidase S41A family
LuPra_RS25745	COG4946	Tricorn protease homolog
LuPra_RS25775	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
LuPra_RS25800	COG3177	Filamentation induced by cAMP protein fic
LuPra_RS25840	COG0515	serine threonine protein kinase
LuPra_RS25865	COG3177	Filamentation induced by cAMP protein fic
LuPra_RS25885	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LuPra_RS25895	COG2382	esterase
LuPra_RS25900	COG1609	Transcriptional regulator
LuPra_RS25935	COG1132	(ABC) transporter
LuPra_RS25940	COG1132	(ABC) transporter
LuPra_RS25945	COG0577	efflux transmembrane transporter activity
LuPra_RS25945	COG1136	(ABC) transporter
LuPra_RS25975	COG0456	acetyltransferase
LuPra_RS25980	COG0673	inositol 2-dehydrogenase activity
LuPra_RS26040	COG0515	serine threonine protein kinase
LuPra_RS26040	COG2815	serine threonine protein kinase
LuPra_RS26050	COG2815	serine threonine protein kinase
LuPra_RS26050	COG0515	serine threonine protein kinase
LuPra_RS26085	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LuPra_RS26095	COG2080	2 iron, 2 sulfur cluster binding
LuPra_RS26100	COG0667	Aldo Keto reductase
LuPra_RS26110	COG4977	sequence-specific DNA binding
LuPra_RS26125	COG0673	inositol 2-dehydrogenase activity
LuPra_RS26145	COG0312	modulator of DNA gyrase
LuPra_RS26150	COG1695	Transcriptional regulator
LuPra_RS26170	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LuPra_RS26190	COG0577	efflux transmembrane transporter activity
LuPra_RS26190	COG1136	(ABC) transporter
LuPra_RS26205	COG0726	polysaccharide deacetylase
LuPra_RS26250	COG1028	Short-chain dehydrogenase reductase Sdr
LuPra_RS26260	COG1309	transcriptional regulator
LuPra_RS26280	COG3391	amine dehydrogenase activity
LuPra_RS26300	COG0789	Transcriptional regulator
LuPra_RS26305	COG1028	Short-chain dehydrogenase reductase Sdr
LuPra_RS26310	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LuPra_RS26355	COG3655	Transcriptional regulator
LuPra_RS26365	COG0577	efflux transmembrane transporter activity
LuPra_RS26365	COG1136	(ABC) transporter
LuPra_RS26395	COG1136	(ABC) transporter
LuPra_RS26395	COG0577	efflux transmembrane transporter activity
LuPra_RS26400	COG1695	Transcriptional regulator
LuPra_RS26405	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
LuPra_RS26445	COG0489	protein tyrosine kinase activity
LuPra_RS26450	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
LuPra_RS26455	COG0535	radical SAM domain protein
LuPra_RS26505	COG1845	cytochrome c oxidase, subunit III
LuPra_RS26510	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LuPra_RS26530	COG3583	domain protein
LuPra_RS26530	COG3584	3D domain protein
LuPra_RS26545	COG0598	Magnesium transport protein CorA
LuPra_RS26565	COG3876	Protein conserved in bacteria
LuPra_RS26570	COG0515	serine threonine protein kinase
LuPra_RS26570	COG2815	serine threonine protein kinase
LuPra_RS26590	COG2205	protein histidine kinase activity
LuPra_RS26605	COG0604	alcohol dehydrogenase
LuPra_RS26630	COG2851	Citrate transporter
LuPra_RS26665	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LuPra_RS26670	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LuPra_RS26675	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LuPra_RS26715	COG1486	melibiose metabolic process
LuPra_RS26740	COG0471	metal ion transport
LuPra_RS26745	COG3590	peptidase
LuPra_RS26770	COG0515	serine threonine protein kinase
LuPra_RS26775	COG0667	Aldo Keto reductase
LuPra_RS26815	COG0006	proline dipeptidase activity
LuPra_RS26840	COG2010	Cytochrome c
LuPra_RS26850	COG2198	Histidine kinase
LuPra_RS26850	COG0784	Response regulator, receiver
LuPra_RS26850	COG2205	protein histidine kinase activity
LuPra_RS26865	COG1752	Esterase of the alpha-beta hydrolase superfamily
LuPra_RS26880	COG2326	polyphosphate kinase activity
LuPra_RS26895	COG0137	argininosuccinate synthase activity
LuPra_RS26900	COG5002	protein histidine kinase activity
LuPra_RS26900	COG0784	Response regulator, receiver
LuPra_RS26900	COG2205	protein histidine kinase activity
LuPra_RS26905	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LuPra_RS26910	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
LuPra_RS26920	COG0330	HflC and HflK could
LuPra_RS26935	COG0544	peptidyl-prolyl cis-trans isomerase activity
LuPra_RS26940	COG0544	peptidyl-prolyl cis-trans isomerase activity
LuPra_RS26945	COG0740	serine-type endopeptidase activity
LuPra_RS26950	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LuPra_RS26955	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LuPra_RS26960	COG0218	Necessary for normal cell division and for the maintenance of normal septation
LuPra_RS26965	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LuPra_RS26970	COG0667	Aldo Keto reductase
LuPra_RS26985	COG0254	rRNA binding
LuPra_RS26995	COG1111	helicase
LuPra_RS26995	COG1205	dead DEAH box helicase
LuPra_RS27005	COG1115	amino acid carrier protein
LuPra_RS27010	COG1028	Short-chain dehydrogenase reductase Sdr
LuPra_RS27025	COG2267	carboxylic ester hydrolase activity
LuPra_RS27040	COG1612	heme a metabolic process
LuPra_RS27040	COG0109	protoheme IX farnesyltransferase activity
LuPra_RS27050	COG2321	neutral zinc metallopeptidase
LuPra_RS27070	COG0346	lactoylglutathione lyase activity
LuPra_RS27100	COG1832	CoA-binding protein
LuPra_RS27110	COG0114	fumarate hydratase activity
LuPra_RS27145	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LuPra_RS27155	COG3852	Histidine kinase
LuPra_RS27160	COG2204	response regulator
LuPra_RS27185	COG0729	surface antigen
LuPra_RS27195	COG0511	ligase activity, forming carbon-carbon bonds
LuPra_RS27200	COG0439	Biotin carboxylase
LuPra_RS27205	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LuPra_RS27210	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LuPra_RS27240	COG1113	amino acid transport
LuPra_RS27265	COG0488	(ABC) transporter
LuPra_RS27270	COG5002	protein histidine kinase activity
LuPra_RS27275	COG2204	response regulator
LuPra_RS27295	COG1754	DNA topoisomerase type I activity
LuPra_RS27295	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LuPra_RS27300	COG0758	DNA mediated transformation
LuPra_RS27315	COG0261	This protein binds to 23S rRNA in the presence of protein L20
LuPra_RS27320	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LuPra_RS27325	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LuPra_RS27330	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LuPra_RS27335	COG0799	negative regulation of ribosome biogenesis
LuPra_RS27350	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LuPra_RS27355	COG0019	diaminopimelate decarboxylase activity
LuPra_RS27360	COG1595	DNA-templated transcription, initiation
LuPra_RS27365	COG1366	Belongs to the anti-sigma-factor antagonist family
LuPra_RS27390	COG1595	DNA-templated transcription, initiation
LuPra_RS27395	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
LuPra_RS27400	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LuPra_RS27410	COG2197	response regulator
LuPra_RS27415	COG3851	Histidine kinase
LuPra_RS27505	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LuPra_RS27545	COG4964	Belongs to the GSP D family
LuPra_RS27605	COG2770	Histidine kinase
LuPra_RS27605	COG2208	phosphoserine phosphatase activity
LuPra_RS27640	COG0070	glutamate synthase
LuPra_RS27640	COG0069	glutamate synthase activity
LuPra_RS27640	COG0067	glutamate synthase
LuPra_RS27705	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LuPra_RS27715	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LuPra_RS27730	COG0463	Glycosyl transferase, family 2
LuPra_RS27745	COG4948	Mandelate Racemase Muconate Lactonizing
LuPra_RS27765	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LuPra_RS27785	COG0405	Gamma-glutamyltransferase
LuPra_RS27790	COG3959	Transketolase, thiamine diphosphate binding domain
LuPra_RS27800	COG0473	3-isopropylmalate dehydrogenase activity
LuPra_RS27805	COG2937	Belongs to the GPAT DAPAT family
LuPra_RS27810	COG0506	proline dehydrogenase activity
LuPra_RS27820	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LuPra_RS27830	COG4221	oxidoreductase activity
LuPra_RS27840	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LuPra_RS27845	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LuPra_RS27875	COG1022	Amp-dependent synthetase and ligase
LuPra_RS27880	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LuPra_RS27890	COG0837	glucose binding
LuPra_RS27905	COG3661	Belongs to the glycosyl hydrolase 67 family
LuPra_RS27930	COG2815	serine threonine protein kinase
LuPra_RS27930	COG0515	serine threonine protein kinase
LuPra_RS27940	COG1183	phosphatidylcholine synthase activity
LuPra_RS27950	COG1201	RNA secondary structure unwinding
LuPra_RS27955	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LuPra_RS27970	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LuPra_RS27980	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LuPra_RS27980	COG2169	Transcriptional regulator
LuPra_RS27990	COG0251	oxidation-reduction process
LuPra_RS28010	COG1131	(ABC) transporter
LuPra_RS28025	COG0259	pyridoxamine-phosphate oxidase activity
LuPra_RS28040	COG2081	HI0933 family
LuPra_RS28050	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LuPra_RS28050	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LuPra_RS28060	COG0628	permease
LuPra_RS28070	COG1074	ATP-dependent DNA helicase activity
LuPra_RS28110	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
LuPra_RS28115	COG3005	denitrification pathway
LuPra_RS28190	COG3459	Glycosyltransferase 36 associated
LuPra_RS28195	COG2366	antibiotic biosynthetic process
LuPra_RS28200	COG2902	Dehydrogenase
LuPra_RS28220	COG3119	arylsulfatase activity
LuPra_RS28245	COG2084	Dehydrogenase
LuPra_RS28250	COG2951	lytic endotransglycosylase activity
LuPra_RS28255	COG0678	peroxiredoxin activity
LuPra_RS28300	COG0154	amidase activity
LuPra_RS28305	COG0154	amidase activity
LuPra_RS28340	COG0671	phosphoesterase, PA-phosphatase related
LuPra_RS28355	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LuPra_RS28370	COG2080	2 iron, 2 sulfur cluster binding
LuPra_RS28385	COG0564	pseudouridine synthase activity
LuPra_RS28395	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LuPra_RS28405	COG3876	Protein conserved in bacteria
LuPra_RS28445	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LuPra_RS28450	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
LuPra_RS28455	COG0527	aspartate kinase activity
LuPra_RS28480	COG0154	amidase activity
LuPra_RS28510	COG0489	protein tyrosine kinase activity
LuPra_RS28535	COG1074	ATP-dependent DNA helicase activity
LuPra_RS28695	COG3657	addiction module killer protein
LuPra_RS28705	COG0671	phosphoesterase, PA-phosphatase related
LuPra_RS28710	COG2271	Major facilitator Superfamily
LuPra_RS28715	COG2205	protein histidine kinase activity
LuPra_RS28715	COG2198	Histidine kinase
LuPra_RS28715	COG0784	Response regulator, receiver
LuPra_RS28725	COG1136	(ABC) transporter
LuPra_RS28725	COG0577	efflux transmembrane transporter activity
LuPra_RS28730	COG1136	(ABC) transporter
LuPra_RS28730	COG0577	efflux transmembrane transporter activity
LuPra_RS28765	COG0275	rRNA processing
LuPra_RS28795	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LuPra_RS28815	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
LuPra_RS28860	COG0539	negative regulation of cytoplasmic translation
LuPra_RS28865	COG0338	D12 class N6 adenine-specific DNA methyltransferase
LuPra_RS28870	COG0746	molybdenum cofactor guanylyltransferase activity
LuPra_RS28880	COG0546	phosphoglycolate phosphatase activity
LuPra_RS28885	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
LuPra_RS28895	COG0316	Belongs to the HesB IscA family
LuPra_RS28900	COG1012	belongs to the aldehyde dehydrogenase family
LuPra_RS28925	COG0351	phosphomethylpyrimidine kinase
LuPra_RS28925	COG0352	thiamine-phosphate diphosphorylase activity
LuPra_RS28930	COG0314	molybdopterin synthase activity
LuPra_RS28935	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LuPra_RS28940	COG2890	protein-(glutamine-N5) methyltransferase activity
LuPra_RS28945	COG0537	adenosine 5'-monophosphoramidase activity
LuPra_RS28950	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LuPra_RS28955	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LuPra_RS28965	COG0564	pseudouridine synthase activity
LuPra_RS28970	COG0494	nUDIX hydrolase
LuPra_RS28995	COG0227	Belongs to the bacterial ribosomal protein bL28 family
LuPra_RS29020	COG0402	S-adenosylhomocysteine deaminase activity
LuPra_RS29030	COG0848	biopolymer transport protein
LuPra_RS29035	COG0848	biopolymer transport protein
LuPra_RS29045	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
LuPra_RS29055	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LuPra_RS29060	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LuPra_RS29065	COG1862	Preprotein translocase
LuPra_RS29070	COG0343	queuine tRNA-ribosyltransferase activity
LuPra_RS29075	COG1181	Belongs to the D-alanine--D-alanine ligase family
LuPra_RS29085	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LuPra_RS29095	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LuPra_RS29100	COG0285	dihydrofolate synthase activity
LuPra_RS29105	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
LuPra_RS29130	COG0501	Belongs to the peptidase M48B family
LuPra_RS29140	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
LuPra_RS29145	COG1643	Atp-dependent helicase
LuPra_RS29155	COG0698	ribose 5-phosphate isomerase
LuPra_RS29160	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LuPra_RS29165	COG1199	ATP-dependent helicase activity
LuPra_RS29205	COG0481	GTPase activity
LuPra_RS29210	COG0372	Belongs to the citrate synthase family
LuPra_RS29215	COG1215	transferase activity, transferring glycosyl groups
LuPra_RS29220	COG1193	negative regulation of DNA recombination
LuPra_RS29225	COG0358	DNA primase activity
LuPra_RS29290	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LuPra_RS29315	COG0492	ferredoxin-NADP+ reductase activity
LuPra_RS29325	COG2133	pyrroloquinoline quinone binding
LuPra_RS29335	COG1496	oxidoreductase activity
LuPra_RS29360	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LuPra_RS29370	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LuPra_RS29375	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LuPra_RS29385	COG0772	Belongs to the SEDS family
LuPra_RS29390	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LuPra_RS29395	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LuPra_RS29400	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LuPra_RS29405	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LuPra_RS29410	COG0768	penicillin binding
LuPra_RS29420	COG0275	rRNA processing
LuPra_RS29425	COG2001	Belongs to the MraZ family
LuPra_RS29435	COG1215	transferase activity, transferring glycosyl groups
LuPra_RS29440	COG0463	Glycosyl transferase, family 2
LuPra_RS29445	COG0463	Glycosyl transferase, family 2
LuPra_RS29450	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LuPra_RS29480	COG0728	peptidoglycan biosynthetic process
LuPra_RS29505	COG0022	dehydrogenase e1 component
LuPra_RS29515	COG2197	response regulator
LuPra_RS29520	COG1024	Enoyl-CoA hydratase
LuPra_RS29530	COG1217	gtp-binding protein TYPA
LuPra_RS29535	COG0784	Response regulator, receiver
LuPra_RS29535	COG5002	protein histidine kinase activity
LuPra_RS29535	COG2205	protein histidine kinase activity
LuPra_RS29545	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LuPra_RS29550	COG0356	it plays a direct role in the translocation of protons across the membrane
LuPra_RS29575	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LuPra_RS29580	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LuPra_RS29585	COG0181	hydroxymethylbilane synthase activity
LuPra_RS29595	COG0113	porphobilinogen synthase activity
LuPra_RS29600	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LuPra_RS29605	COG0123	including yeast histone deacetylase and acetoin utilization protein
LuPra_RS29625	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LuPra_RS29630	COG4783	chaperone-mediated protein folding
LuPra_RS29650	COG0109	protoheme IX farnesyltransferase activity
LuPra_RS29655	COG2322	membrane
LuPra_RS29660	COG1028	Short-chain dehydrogenase reductase Sdr
LuPra_RS29680	COG5002	protein histidine kinase activity
LuPra_RS29685	COG0745	RESPONSE REGULATOR receiver
LuPra_RS29705	COG5002	protein histidine kinase activity
LuPra_RS29710	COG0745	RESPONSE REGULATOR receiver
LuPra_RS29725	COG3876	Protein conserved in bacteria
LuPra_RS29730	COG1250	3-hydroxyacyl-CoA dehydrogenase
LuPra_RS29730	COG1024	Enoyl-CoA hydratase
LuPra_RS29735	COG0596	Alpha beta hydrolase
LuPra_RS29740	COG0183	Belongs to the thiolase family
LuPra_RS29750	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
LuPra_RS29755	COG1960	acyl-CoA dehydrogenase activity
LuPra_RS29765	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LuPra_RS29845	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LuPra_RS29850	COG2897	thiosulfate sulfurtransferase activity
LuPra_RS29860	COG0179	Fumarylacetoacetate (FAA) hydrolase
LuPra_RS29895	COG1830	Aldolase
LuPra_RS29900	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LuPra_RS29930	COG0354	folic acid binding
LuPra_RS29945	COG0577	efflux transmembrane transporter activity
LuPra_RS29950	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LuPra_RS29965	COG2815	serine threonine protein kinase
LuPra_RS29965	COG0515	serine threonine protein kinase
LuPra_RS29970	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LuPra_RS29975	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LuPra_RS29980	COG2814	Major facilitator Superfamily
LuPra_RS29985	COG1028	Short-chain dehydrogenase reductase Sdr
LuPra_RS29995	COG1253	flavin adenine dinucleotide binding
LuPra_RS30000	COG1253	flavin adenine dinucleotide binding
LuPra_RS30005	COG1595	DNA-templated transcription, initiation
LuPra_RS30015	COG0508	dehydrogenase complex catalyzes the overall conversion of
LuPra_RS30020	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LuPra_RS30025	COG2204	response regulator
LuPra_RS30030	COG0535	radical SAM domain protein
LuPra_RS30035	COG0747	negative chemotaxis
LuPra_RS30040	COG4191	Histidine kinase
LuPra_RS30055	COG1193	negative regulation of DNA recombination
LuPra_RS30060	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LuPra_RS30075	COG0730	response to heat
LuPra_RS30080	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LuPra_RS30090	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LuPra_RS30140	COG0393	Putative heavy-metal-binding
LuPra_RS30145	COG2154	pterin-4-alpha-carbinolamine dehydratase
LuPra_RS30150	COG2022	thiamine diphosphate biosynthetic process
LuPra_RS30150	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LuPra_RS30180	COG0076	glutamate decarboxylase activity
LuPra_RS30195	COG0436	Aminotransferase
LuPra_RS30215	COG0640	Transcriptional regulator
LuPra_RS30220	COG3829	transcription factor binding
LuPra_RS30225	COG1404	Belongs to the peptidase S8 family
LuPra_RS30230	COG4166	transmembrane transport
LuPra_RS30240	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LuPra_RS30245	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LuPra_RS30260	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LuPra_RS30265	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
LuPra_RS30270	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LuPra_RS30275	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LuPra_RS30280	COG0131	Imidazoleglycerol-phosphate dehydratase
LuPra_RS30285	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LuPra_RS30290	COG0107	imidazoleglycerol-phosphate synthase activity
LuPra_RS30295	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LuPra_RS30310	COG1305	Transglutaminase-like
LuPra_RS30320	COG2308	Evidence 4 Homologs of previously reported genes of
LuPra_RS30330	COG1595	DNA-templated transcription, initiation
LuPra_RS30365	COG3361	conserved protein (COG2071)
LuPra_RS30380	COG3119	arylsulfatase activity
LuPra_RS30390	COG3964	amidohydrolase
LuPra_RS30440	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LuPra_RS30445	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LuPra_RS30450	COG0659	secondary active sulfate transmembrane transporter activity
LuPra_RS30465	COG3591	Belongs to the peptidase S1B family
LuPra_RS30465	COG1864	DNA RNA non-specific endonuclease
LuPra_RS30495	COG1902	pentaerythritol trinitrate reductase activity
LuPra_RS30500	COG1858	cytochrome C peroxidase
LuPra_RS30515	COG0719	Fe-S assembly protein
LuPra_RS30520	COG0396	ATPase activity
LuPra_RS30525	COG0719	Fe-S assembly protein
LuPra_RS30530	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LuPra_RS30540	COG2151	metal-sulfur cluster biosynthetic enzyme
LuPra_RS30605	COG0419	ATPase involved in DNA repair
LuPra_RS30675	COG0513	Belongs to the DEAD box helicase family
LuPra_RS30710	COG1615	UPF0182 protein
LuPra_RS30730	COG1619	proteins homologs of microcin C7 resistance protein MccF
LuPra_RS30740	COG0174	glutamine synthetase
LuPra_RS30745	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LuPra_RS30770	COG1034	ATP synthesis coupled electron transport
LuPra_RS30780	COG2208	phosphoserine phosphatase activity
LuPra_RS30780	COG2770	Histidine kinase
LuPra_RS30785	COG0156	8-amino-7-oxononanoate synthase activity
LuPra_RS30815	COG5002	protein histidine kinase activity
LuPra_RS30820	COG0745	RESPONSE REGULATOR receiver
LuPra_RS30855	COG0569	domain protein
LuPra_RS30860	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LuPra_RS30865	COG2080	2 iron, 2 sulfur cluster binding
LuPra_RS30870	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LuPra_RS30890	COG1522	sequence-specific DNA binding
LuPra_RS30895	COG0697	spore germination
LuPra_RS30905	COG1028	Short-chain dehydrogenase reductase Sdr
LuPra_RS30910	COG0667	Aldo Keto reductase
LuPra_RS30930	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
LuPra_RS30940	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LuPra_RS31000	COG2204	response regulator
LuPra_RS31005	COG3852	Histidine kinase
LuPra_RS31040	COG2244	polysaccharide biosynthetic process
LuPra_RS31055	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LuPra_RS31075	COG0275	rRNA processing
LuPra_RS31085	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LuPra_RS31120	COG0438	transferase activity, transferring glycosyl groups
LuPra_RS31145	COG1215	transferase activity, transferring glycosyl groups
LuPra_RS31155	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LuPra_RS31170	COG0673	inositol 2-dehydrogenase activity
LuPra_RS31180	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LuPra_RS31190	COG0489	protein tyrosine kinase activity
LuPra_RS31195	COG3409	Peptidoglycan-binding domain 1 protein
LuPra_RS31195	COG3267	Type II secretory pathway component ExeA
LuPra_RS31200	COG3206	protein involved in exopolysaccharide biosynthesis
LuPra_RS31200	COG0489	protein tyrosine kinase activity
LuPra_RS31255	COG2204	response regulator
LuPra_RS31275	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LuPra_RS31305	COG2197	response regulator
LuPra_RS31315	COG4585	Histidine kinase
LuPra_RS31325	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
LuPra_RS31325	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
LuPra_RS31345	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LuPra_RS31350	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LuPra_RS31355	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LuPra_RS31360	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LuPra_RS31365	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LuPra_RS31385	COG1475	DNA binding
LuPra_RS31390	COG1192	Involved in chromosome partitioning
LuPra_RS31395	COG0357	Ribosomal RNA small subunit methyltransferase G
LuPra_RS31400	COG0445	tRNA wobble uridine modification
LuPra_RS31405	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LuPra_RS31415	COG0706	membrane insertase activity
LuPra_RS31420	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
LuPra_RS31425	COG0594	ribonuclease P activity
LuPra_RS31430	COG0230	Belongs to the bacterial ribosomal protein bL34 family