locus-tag	class	description
C1N55_RS00010	COG0592	DNA-directed DNA polymerase activity
C1N55_RS00015	COG2501	S4 domain
C1N55_RS00025	COG0187	DNA topoisomerase II activity
C1N55_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C1N55_RS00065	COG0517	IMP dehydrogenase activity
C1N55_RS00065	COG0516	GMP reductase activity
C1N55_RS00075	COG0367	asparagine synthase
C1N55_RS00080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C1N55_RS00085	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
C1N55_RS00090	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
C1N55_RS00100	COG2031	fatty acid transporter
C1N55_RS00105	COG0436	Aminotransferase
C1N55_RS00115	COG0590	tRNA wobble adenosine to inosine editing
C1N55_RS00120	COG1428	Deoxynucleoside kinase
C1N55_RS00125	COG1428	Deoxynucleoside kinase
C1N55_RS00135	COG1120	ATPase activity
C1N55_RS00155	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
C1N55_RS00160	COG1301	dicarboxylic acid transport
C1N55_RS00180	COG1131	(ABC) transporter
C1N55_RS00195	COG0714	Associated with various cellular activities
C1N55_RS00215	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C1N55_RS00225	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
C1N55_RS00290	COG0813	purine-nucleoside phosphorylase activity
C1N55_RS00295	COG1982	Orn Lys Arg decarboxylase major
C1N55_RS00300	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
C1N55_RS00305	COG3870	Protein conserved in bacteria
C1N55_RS00310	COG1728	Protein conserved in bacteria
C1N55_RS00315	COG0470	DNA polymerase III
C1N55_RS00320	COG1774	PSP1 C-terminal conserved region
C1N55_RS00325	COG4467	Involved in initiation control of chromosome replication
C1N55_RS00330	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
C1N55_RS00335	COG2827	Endonuclease containing a URI domain
C1N55_RS00340	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
C1N55_RS00345	COG2002	toxin-antitoxin pair type II binding
C1N55_RS00355	COG0084	hydrolase, TatD family'
C1N55_RS00360	COG3584	3D domain protein
C1N55_RS00360	COG3583	domain protein
C1N55_RS00375	COG4466	Protein conserved in bacteria
C1N55_RS00385	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
C1N55_RS00390	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C1N55_RS00395	COG0251	oxidation-reduction process
C1N55_RS00410	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C1N55_RS00420	COG0193	aminoacyl-tRNA hydrolase activity
C1N55_RS00430	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C1N55_RS00435	COG2002	toxin-antitoxin pair type II binding
C1N55_RS00440	COG2244	polysaccharide biosynthetic process
C1N55_RS00445	COG3956	TIGRFAM MazG family protein
C1N55_RS00450	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
C1N55_RS00465	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
C1N55_RS00470	COG1098	S1 RNA binding domain
C1N55_RS00485	COG0037	tRNA processing
C1N55_RS00485	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
C1N55_RS00490	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
C1N55_RS00495	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C1N55_RS00500	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
C1N55_RS00505	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
C1N55_RS00510	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C1N55_RS00515	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C1N55_RS00525	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
C1N55_RS00530	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
C1N55_RS00535	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C1N55_RS00540	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C1N55_RS00545	COG2318	DinB family
C1N55_RS00630	COG1309	transcriptional regulator
C1N55_RS00635	COG1511	domain protein
C1N55_RS00645	COG2224	Isocitrate lyase
C1N55_RS00650	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
C1N55_RS00665	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C1N55_RS00700	COG0165	Argininosuccinate lyase
C1N55_RS00720	COG2323	membrane
C1N55_RS00730	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C1N55_RS00730	COG2111	Na H antiporter
C1N55_RS00735	COG2111	Na H antiporter
C1N55_RS00740	COG1006	Multisubunit Na H antiporter MnhC subunit
C1N55_RS00745	COG0651	ATP synthesis coupled electron transport
C1N55_RS00750	COG1863	multisubunit Na H antiporter MnhE subunit
C1N55_RS00755	COG2212	antiporter activity
C1N55_RS00760	COG1320	monovalent cation:proton antiporter activity
C1N55_RS00770	COG1131	(ABC) transporter
C1N55_RS00785	COG1408	metallophosphoesterase
C1N55_RS00790	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C1N55_RS00795	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
C1N55_RS00800	COG1744	ABC transporter substrate-binding protein PnrA-like
C1N55_RS00805	COG0840	transmembrane signaling receptor activity
C1N55_RS00820	COG1595	DNA-templated transcription, initiation
C1N55_RS00845	COG0494	nUDIX hydrolase
C1N55_RS00855	COG1804	L-carnitine dehydratase bile acid-inducible protein F
C1N55_RS00875	COG0753	catalase activity
C1N55_RS00885	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
C1N55_RS00895	COG2807	transmembrane transport
C1N55_RS00900	COG0833	amino acid
C1N55_RS00910	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C1N55_RS00920	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C1N55_RS00930	COG2391	methyltransferase activity
C1N55_RS00935	COG0425	Belongs to the sulfur carrier protein TusA family
C1N55_RS00950	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C1N55_RS00955	COG3829	transcription factor binding
C1N55_RS00960	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
C1N55_RS00980	COG2409	Drug exporters of the RND superfamily
C1N55_RS00980	COG1033	growth of symbiont in host cell
C1N55_RS00985	COG1028	Short-chain dehydrogenase reductase Sdr
C1N55_RS01000	COG4948	Mandelate Racemase Muconate Lactonizing
C1N55_RS01005	COG3949	Membrane
C1N55_RS01025	COG0589	response to stress
C1N55_RS01030	COG0659	secondary active sulfate transmembrane transporter activity
C1N55_RS01040	COG1028	Short-chain dehydrogenase reductase Sdr
C1N55_RS01050	COG1132	(ABC) transporter
C1N55_RS01055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C1N55_RS01055	COG2207	Transcriptional regulator
C1N55_RS01060	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C1N55_RS01065	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C1N55_RS01070	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C1N55_RS01075	COG1120	ATPase activity
C1N55_RS01080	COG2819	hydrolase of the alpha beta superfamily
C1N55_RS01095	COG3064	Membrane
C1N55_RS01095	COG4991	sh3 domain protein
C1N55_RS01095	COG0515	serine threonine protein kinase
C1N55_RS01110	COG2814	Major facilitator Superfamily
C1N55_RS01115	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C1N55_RS01155	COG0861	Integral membrane protein TerC family
C1N55_RS01160	COG2508	Transcriptional regulator
C1N55_RS01190	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C1N55_RS01195	COG0739	heme binding
C1N55_RS01205	COG0346	lactoylglutathione lyase activity
C1N55_RS01215	COG0346	lactoylglutathione lyase activity
C1N55_RS01220	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C1N55_RS01225	COG0400	carboxylic ester hydrolase activity
C1N55_RS01330	COG0697	spore germination
C1N55_RS01365	COG2032	superoxide dismutase activity
C1N55_RS01370	COG2358	TRAP transporter, solute receptor (TAXI family
C1N55_RS01385	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
C1N55_RS01390	COG1473	amidohydrolase
C1N55_RS01425	COG3655	Transcriptional regulator
C1N55_RS01445	COG0697	spore germination
C1N55_RS01470	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
C1N55_RS01475	COG2873	o-acetylhomoserine
C1N55_RS01485	COG1595	DNA-templated transcription, initiation
C1N55_RS01500	COG0166	Belongs to the GPI family
C1N55_RS01505	COG0697	spore germination
C1N55_RS01510	COG1846	Transcriptional regulator
C1N55_RS01515	COG1764	response to oxidative stress
C1N55_RS01520	COG0386	Belongs to the glutathione peroxidase family
C1N55_RS01540	COG1968	undecaprenyl-diphosphatase activity
C1N55_RS01545	COG3773	Cell wall hydrolase
C1N55_RS01550	COG0840	transmembrane signaling receptor activity
C1N55_RS01560	COG1012	belongs to the aldehyde dehydrogenase family
C1N55_RS01575	COG0726	polysaccharide deacetylase
C1N55_RS01585	COG3610	response to peptide
C1N55_RS01590	COG2199	diguanylate cyclase activity
C1N55_RS01590	COG2200	EAL domain
C1N55_RS01590	COG2202	Pas domain
C1N55_RS01595	COG1132	(ABC) transporter
C1N55_RS01600	COG1132	(ABC) transporter
C1N55_RS01605	COG0456	acetyltransferase
C1N55_RS01610	COG1575	Belongs to the MenA family. Type 1 subfamily
C1N55_RS01615	COG0346	lactoylglutathione lyase activity
C1N55_RS01625	COG0667	Aldo Keto reductase
C1N55_RS01630	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C1N55_RS01645	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C1N55_RS01650	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C1N55_RS01665	COG2076	Multidrug Resistance protein
C1N55_RS01670	COG2076	Multidrug Resistance protein
C1N55_RS01695	COG1247	-acetyltransferase
C1N55_RS01700	COG1054	Belongs to the UPF0176 family
C1N55_RS01705	COG0425	Belongs to the sulfur carrier protein TusA family
C1N55_RS01705	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C1N55_RS01710	COG3973	AAA domain
C1N55_RS01730	COG3226	Transcriptional regulator
C1N55_RS01735	COG0584	glycerophosphoryl diester phosphodiesterase
C1N55_RS01750	COG0778	Nitroreductase
C1N55_RS01770	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C1N55_RS01795	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C1N55_RS01805	COG0154	amidase activity
C1N55_RS01810	COG0179	Fumarylacetoacetate (FAA) hydrolase
C1N55_RS01815	COG0405	Gamma-glutamyltransferase
C1N55_RS01820	COG2059	Chromate
C1N55_RS01825	COG2059	Chromate
C1N55_RS01830	COG2072	flavoprotein involved in K transport
C1N55_RS01835	COG2351	hydroxyisourate hydrolase activity
C1N55_RS01840	COG3648	Uricase
C1N55_RS01840	COG3195	allantoin biosynthetic process
C1N55_RS01845	COG2233	PERMEase
C1N55_RS01850	COG2508	Transcriptional regulator
C1N55_RS01855	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C1N55_RS01860	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
C1N55_RS01895	COG2310	stress, protein
C1N55_RS01900	COG2310	stress, protein
C1N55_RS01905	COG2310	stress, protein
C1N55_RS01910	COG0861	Integral membrane protein TerC family
C1N55_RS01925	COG1358	cellular component organization or biogenesis
C1N55_RS01940	COG2340	Cysteine-rich secretory protein family
C1N55_RS01945	COG2304	oxidoreductase activity
C1N55_RS01950	COG2304	oxidoreductase activity
C1N55_RS01985	COG0300	oxidoreductase activity
C1N55_RS01995	COG2169	Transcriptional regulator
C1N55_RS02000	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
C1N55_RS02005	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C1N55_RS02010	COG0640	Transcriptional regulator
C1N55_RS02020	COG0640	Transcriptional regulator
C1N55_RS02030	COG1834	amidinotransferase
C1N55_RS02035	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C1N55_RS02090	COG0305	Participates in initiation and elongation during chromosome replication
C1N55_RS02125	COG3066	DNA modification
C1N55_RS02155	COG1960	acyl-CoA dehydrogenase activity
C1N55_RS02170	COG2358	TRAP transporter, solute receptor (TAXI family
C1N55_RS02180	COG1804	L-carnitine dehydratase bile acid-inducible protein F
C1N55_RS02220	COG1024	Enoyl-CoA hydratase
C1N55_RS02225	COG5609	conserved protein (DUF2294)
C1N55_RS02255	COG2814	Major facilitator Superfamily
C1N55_RS02280	COG0697	spore germination
C1N55_RS02295	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
C1N55_RS02310	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C1N55_RS02370	COG0745	RESPONSE REGULATOR receiver
C1N55_RS02375	COG3850	Histidine kinase
C1N55_RS02375	COG5002	protein histidine kinase activity
C1N55_RS02380	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C1N55_RS02415	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C1N55_RS02435	COG2814	Major facilitator Superfamily
C1N55_RS02440	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C1N55_RS02445	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C1N55_RS02450	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C1N55_RS02455	COG1120	ATPase activity
C1N55_RS02475	COG1757	Na H antiporter
C1N55_RS02525	COG1959	2 iron, 2 sulfur cluster binding
C1N55_RS02530	COG2910	NAD(P)H-binding
C1N55_RS02540	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C1N55_RS02545	COG0789	Transcriptional regulator
C1N55_RS02545	COG4978	Transcriptional regulator
C1N55_RS02550	COG2814	Major facilitator Superfamily
C1N55_RS02555	COG0840	transmembrane signaling receptor activity
C1N55_RS02565	COG1131	(ABC) transporter
C1N55_RS02575	COG2364	Membrane
C1N55_RS02580	COG2153	protein acetylation
C1N55_RS02585	COG1846	Transcriptional regulator
C1N55_RS02590	COG0456	acetyltransferase
C1N55_RS02605	COG1113	amino acid transport
C1N55_RS02620	COG0267	Belongs to the bacterial ribosomal protein bL33 family
C1N55_RS02625	COG0523	cobalamin synthesis protein
C1N55_RS02645	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C1N55_RS02650	COG0477	Major facilitator Superfamily
C1N55_RS02670	COG4585	Histidine kinase
C1N55_RS02675	COG2197	response regulator
C1N55_RS02680	COG0668	transmembrane transport
C1N55_RS02690	COG1942	4-Oxalocrotonate Tautomerase
C1N55_RS02695	COG0477	Major facilitator Superfamily
C1N55_RS02700	COG0583	DNA-binding transcription factor activity
C1N55_RS02705	COG0702	epimerase
C1N55_RS02720	COG1268	BioY protein
C1N55_RS02735	COG0583	DNA-binding transcription factor activity
C1N55_RS02740	COG0745	RESPONSE REGULATOR receiver
C1N55_RS02755	COG2205	protein histidine kinase activity
C1N55_RS02780	COG0697	spore germination
C1N55_RS02785	COG2207	Transcriptional regulator
C1N55_RS02785	COG1917	Cupin 2, conserved barrel domain protein
C1N55_RS02795	COG0456	acetyltransferase
C1N55_RS02810	COG4294	response to UV
C1N55_RS02835	COG0456	acetyltransferase
C1N55_RS02840	COG2318	DinB family
C1N55_RS02860	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C1N55_RS02870	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
C1N55_RS02875	COG3052	prosthetic group binding
C1N55_RS02900	COG0840	transmembrane signaling receptor activity
C1N55_RS02910	COG0583	DNA-binding transcription factor activity
C1N55_RS02915	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C1N55_RS02920	COG1396	sequence-specific DNA binding
C1N55_RS02920	COG1917	Cupin 2, conserved barrel domain protein
C1N55_RS02925	COG1280	lysine exporter protein (LysE YggA)
C1N55_RS02950	COG0406	alpha-ribazole phosphatase activity
C1N55_RS02960	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C1N55_RS02965	COG0569	domain protein
C1N55_RS03020	COG0745	RESPONSE REGULATOR receiver
C1N55_RS03025	COG5002	protein histidine kinase activity
C1N55_RS03055	COG5001	Diguanylate cyclase
C1N55_RS03075	COG0628	permease
C1N55_RS03085	COG2323	membrane
C1N55_RS03110	COG0084	hydrolase, TatD family'
C1N55_RS03115	COG1116	anion transmembrane transporter activity
C1N55_RS03120	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C1N55_RS03130	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C1N55_RS03140	COG1247	-acetyltransferase
C1N55_RS03150	COG1476	TRANSCRIPTIONal
C1N55_RS03170	COG1131	(ABC) transporter
C1N55_RS03190	COG0671	phosphoesterase, PA-phosphatase related
C1N55_RS03210	COG1733	regulation of RNA biosynthetic process
C1N55_RS03215	COG2814	Major facilitator Superfamily
C1N55_RS03220	COG0656	L-ascorbic acid biosynthetic process
C1N55_RS03240	COG1595	DNA-templated transcription, initiation
C1N55_RS03245	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C1N55_RS03260	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C1N55_RS03270	COG1247	-acetyltransferase
C1N55_RS03295	COG0492	ferredoxin-NADP+ reductase activity
C1N55_RS03300	COG0546	phosphoglycolate phosphatase activity
C1N55_RS03305	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C1N55_RS03320	COG3757	hydrolase, family 25
C1N55_RS03320	COG3409	Peptidoglycan-binding domain 1 protein
C1N55_RS03325	COG1028	Short-chain dehydrogenase reductase Sdr
C1N55_RS03330	COG1309	transcriptional regulator
C1N55_RS03335	COG0604	alcohol dehydrogenase
C1N55_RS03340	COG2050	protein possibly involved in aromatic compounds catabolism
C1N55_RS03345	COG0730	response to heat
C1N55_RS03380	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C1N55_RS03385	COG3594	Acyltransferase
C1N55_RS03400	COG2818	Glycosylase
C1N55_RS03405	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C1N55_RS03415	COG1988	membrane-bound metal-dependent
C1N55_RS03420	COG3739	integral membrane protein
C1N55_RS03435	COG0747	negative chemotaxis
C1N55_RS03440	COG0601	transmembrane transport
C1N55_RS03445	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C1N55_RS03450	COG0444	Belongs to the ABC transporter superfamily
C1N55_RS03455	COG4608	Belongs to the ABC transporter superfamily
C1N55_RS03480	COG1742	UPF0060 membrane protein
C1N55_RS03485	COG1902	pentaerythritol trinitrate reductase activity
C1N55_RS03490	COG3361	conserved protein (COG2071)
C1N55_RS03500	COG1335	isochorismatase
C1N55_RS03505	COG2226	methyltransferase
C1N55_RS03515	COG2318	DinB family
C1N55_RS03520	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C1N55_RS03530	COG0604	alcohol dehydrogenase
C1N55_RS03570	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C1N55_RS03580	COG0840	transmembrane signaling receptor activity
C1N55_RS03595	COG3180	Ammonia monooxygenase
C1N55_RS03610	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C1N55_RS03615	COG1595	DNA-templated transcription, initiation
C1N55_RS03625	COG1393	Belongs to the ArsC family
C1N55_RS03630	COG0488	(ABC) transporter
C1N55_RS03655	COG0431	NADPH-dependent FMN reductase
C1N55_RS03660	COG0534	Mate efflux family protein
C1N55_RS03670	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
C1N55_RS03690	COG1937	Protein conserved in bacteria
C1N55_RS03695	COG2608	mercury ion transmembrane transporter activity
C1N55_RS03700	COG2217	Heavy metal translocating P-type atpase
C1N55_RS03710	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C1N55_RS03720	COG0768	penicillin binding
C1N55_RS03725	COG1595	DNA-templated transcription, initiation
C1N55_RS03740	COG1283	sodium-dependent phosphate transmembrane transporter activity
C1N55_RS03760	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
C1N55_RS03770	COG0179	Fumarylacetoacetate (FAA) hydrolase
C1N55_RS03780	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C1N55_RS03795	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C1N55_RS03810	COG1476	TRANSCRIPTIONal
C1N55_RS03815	COG0156	8-amino-7-oxononanoate synthase activity
C1N55_RS03825	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C1N55_RS03830	COG2011	ABC-type metal ion transport system permease component
C1N55_RS03840	COG0436	Aminotransferase
C1N55_RS03845	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C1N55_RS03850	COG2323	membrane
C1N55_RS03860	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C1N55_RS03880	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C1N55_RS03895	COG0133	tryptophan synthase activity
C1N55_RS03900	COG0135	phosphoribosylanthranilate isomerase activity
C1N55_RS03905	COG0134	indole-3-glycerol-phosphate synthase activity
C1N55_RS03925	COG4120	Belongs to the binding-protein-dependent transport system permease family
C1N55_RS03930	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C1N55_RS03930	COG1116	anion transmembrane transporter activity
C1N55_RS03945	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C1N55_RS03950	COG3314	Sporulation integral membrane protein YlbJ
C1N55_RS03955	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C1N55_RS03960	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C1N55_RS03985	COG2363	Small membrane protein
C1N55_RS03990	COG1473	amidohydrolase
C1N55_RS04005	COG3253	May function as heme-dependent peroxidase
C1N55_RS04025	COG1078	dGTPase activity
C1N55_RS04040	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C1N55_RS04045	COG0010	Belongs to the arginase family
C1N55_RS04055	COG0018	arginyl-trna synthetase
C1N55_RS04065	COG0318	PFAM AMP-dependent synthetase and ligase
C1N55_RS04070	COG1960	acyl-CoA dehydrogenase activity
C1N55_RS04075	COG1960	acyl-CoA dehydrogenase activity
C1N55_RS04080	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C1N55_RS04085	COG1120	ATPase activity
C1N55_RS04090	COG2096	Adenosyltransferase
C1N55_RS04095	COG0247	lactate metabolic process
C1N55_RS04095	COG2181	nitrate reductase activity
C1N55_RS04100	COG0183	Belongs to the thiolase family
C1N55_RS04105	COG1250	3-hydroxyacyl-CoA dehydrogenase
C1N55_RS04110	COG1960	acyl-CoA dehydrogenase activity
C1N55_RS04115	COG1960	acyl-CoA dehydrogenase activity
C1N55_RS04120	COG1309	transcriptional regulator
C1N55_RS04125	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
C1N55_RS04125	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
C1N55_RS04125	COG1703	isobutyryl-CoA mutase activity
C1N55_RS04130	COG3343	RNA polymerase activity
C1N55_RS04140	COG0504	CTP synthase activity
C1N55_RS04150	COG2204	response regulator
C1N55_RS04165	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C1N55_RS04170	COG1494	fructose-1,6-bisphosphatase
C1N55_RS04175	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
C1N55_RS04180	COG0254	rRNA binding
C1N55_RS04185	COG1435	thymidine kinase activity
C1N55_RS04205	COG0009	L-threonylcarbamoyladenylate synthase
C1N55_RS04220	COG0840	transmembrane signaling receptor activity
C1N55_RS04225	COG0698	ribose 5-phosphate isomerase
C1N55_RS04245	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
C1N55_RS04260	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
C1N55_RS04295	COG4836	Membrane
C1N55_RS04305	COG2385	sporulation resulting in formation of a cellular spore
C1N55_RS04315	COG1609	Transcriptional regulator
C1N55_RS04325	COG4786	Flagellar basal body rod
C1N55_RS04330	COG4786	Flagellar basal body rod
C1N55_RS04360	COG0629	single-stranded DNA binding
C1N55_RS04365	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C1N55_RS04370	COG4715	Zinc finger, swim domain protein
C1N55_RS04380	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
C1N55_RS04385	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
C1N55_RS04395	COG1361	Conserved repeat domain
C1N55_RS04400	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
C1N55_RS04415	COG1966	Carbon starvation protein
C1N55_RS04440	COG0463	Glycosyl transferase, family 2
C1N55_RS04465	COG0860	N-Acetylmuramoyl-L-alanine amidase
C1N55_RS04490	COG0438	transferase activity, transferring glycosyl groups
C1N55_RS04495	COG0728	peptidoglycan biosynthetic process
C1N55_RS04500	COG1309	transcriptional regulator
C1N55_RS04505	COG0793	Belongs to the peptidase S41A family
C1N55_RS04510	COG1114	Component of the transport system for branched-chain amino acids
C1N55_RS04515	COG1388	LysM domain
C1N55_RS04515	COG0791	NLP P60 protein
C1N55_RS04525	COG0653	protein targeting
C1N55_RS04530	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C1N55_RS04535	COG1316	TRANSCRIPTIONal
C1N55_RS04540	COG1739	Uncharacterized protein family UPF0029
C1N55_RS04545	COG4585	Histidine kinase
C1N55_RS04550	COG2197	response regulator
C1N55_RS04560	COG1307	EDD domain protein, DegV family
C1N55_RS04565	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
C1N55_RS04570	COG1040	competence protein
C1N55_RS04580	COG2747	anti-sigma28 factor FlgM
C1N55_RS04590	COG1256	bacterial-type flagellum assembly
C1N55_RS04590	COG4786	Flagellar basal body rod
C1N55_RS04595	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C1N55_RS04610	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
C1N55_RS04615	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C1N55_RS04640	COG1086	Polysaccharide biosynthesis protein
C1N55_RS04690	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
C1N55_RS04700	COG1028	Short-chain dehydrogenase reductase Sdr
C1N55_RS04715	COG0318	PFAM AMP-dependent synthetase and ligase
C1N55_RS04730	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
C1N55_RS04740	COG2089	acid synthase
C1N55_RS04745	COG4310	Domain of unknown function (DUF2172)
C1N55_RS04755	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C1N55_RS04760	COG0166	Belongs to the GPI family
C1N55_RS04765	COG1334	flagellar protein FlaG
C1N55_RS04770	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
C1N55_RS04780	COG1516	flagellar protein fliS
C1N55_RS04795	COG3344	reverse transcriptase
C1N55_RS04895	COG0653	protein targeting
C1N55_RS04920	COG0556	nucleotide-excision repair
C1N55_RS04925	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C1N55_RS04930	COG3595	metallopeptidase activity
C1N55_RS04935	COG2884	Cell division ATP-binding protein ftsE
C1N55_RS04940	COG2177	Part of the ABC transporter FtsEX involved in
C1N55_RS04945	COG0739	heme binding
C1N55_RS04950	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C1N55_RS04955	COG3409	Peptidoglycan-binding domain 1 protein
C1N55_RS04955	COG0793	Belongs to the peptidase S41A family
C1N55_RS04960	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C1N55_RS04975	COG0398	Pfam SNARE associated Golgi protein
C1N55_RS04990	COG2311	Membrane
C1N55_RS05015	COG4608	Belongs to the ABC transporter superfamily
C1N55_RS05020	COG0601	transmembrane transport
C1N55_RS05030	COG0747	negative chemotaxis
C1N55_RS05035	COG1307	EDD domain protein, DegV family
C1N55_RS05040	COG0561	phosphatase activity
C1N55_RS05045	COG1073	alpha beta
C1N55_RS05050	COG2151	metal-sulfur cluster biosynthetic enzyme
C1N55_RS05055	COG1063	alcohol dehydrogenase
C1N55_RS05060	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C1N55_RS05075	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C1N55_RS05080	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C1N55_RS05090	COG0180	Tryptophanyl-tRNA synthetase
C1N55_RS05095	COG1393	Belongs to the ArsC family
C1N55_RS05110	COG1164	Oligoendopeptidase f
C1N55_RS05115	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
C1N55_RS05120	COG2346	COG2346, Truncated hemoglobins
C1N55_RS05125	COG0741	lytic transglycosylase activity
C1N55_RS05125	COG0739	heme binding
C1N55_RS05125	COG1196	nuclear chromosome segregation
C1N55_RS05130	COG4116	CYTH
C1N55_RS05140	COG2357	RelA SpoT domain protein
C1N55_RS05150	COG0564	pseudouridine synthase activity
C1N55_RS05155	COG2239	Acts as a magnesium transporter
C1N55_RS05180	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C1N55_RS05205	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
C1N55_RS05210	COG2382	esterase
C1N55_RS05215	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C1N55_RS05225	COG1012	belongs to the aldehyde dehydrogenase family
C1N55_RS05230	COG1363	Peptidase, m42
C1N55_RS05235	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C1N55_RS05240	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
C1N55_RS05245	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C1N55_RS05245	COG3320	Male sterility
C1N55_RS05250	COG0861	Integral membrane protein TerC family
C1N55_RS05255	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C1N55_RS05260	COG5002	protein histidine kinase activity
C1N55_RS05265	COG1846	Transcriptional regulator
C1N55_RS05280	COG4873	Protein conserved in bacteria
C1N55_RS05295	COG2084	Dehydrogenase
C1N55_RS05305	COG0784	Response regulator, receiver
C1N55_RS05305	COG0835	chemotaxis
C1N55_RS05330	COG1028	Short-chain dehydrogenase reductase Sdr
C1N55_RS05340	COG0517	IMP dehydrogenase activity
C1N55_RS05345	COG0583	DNA-binding transcription factor activity
C1N55_RS05350	COG2171	N-acyltransferase activity
C1N55_RS05355	COG1473	amidohydrolase
C1N55_RS05360	COG2814	Major facilitator Superfamily
C1N55_RS05365	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
C1N55_RS05370	COG1177	transmembrane transport
C1N55_RS05375	COG1176	ABC-type spermidine putrescine transport system, permease component I
C1N55_RS05390	COG0450	alkyl hydroperoxide reductase
C1N55_RS05395	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C1N55_RS05410	COG0569	domain protein
C1N55_RS05415	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
C1N55_RS05425	COG0561	phosphatase activity
C1N55_RS05430	COG0242	peptide deformylase activity
C1N55_RS05445	COG0508	dehydrogenase complex catalyzes the overall conversion of
C1N55_RS05455	COG3290	protein histidine kinase activity
C1N55_RS05460	COG4565	transcriptional regulatory protein
C1N55_RS05480	COG1380	Effector of murein hydrolase LrgA
C1N55_RS05485	COG1346	cytolysis
C1N55_RS05490	COG1982	Orn Lys Arg decarboxylase major
C1N55_RS05520	COG0483	inositol monophosphate 1-phosphatase activity
C1N55_RS05530	COG1217	gtp-binding protein TYPA
C1N55_RS05540	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C1N55_RS05545	COG1116	anion transmembrane transporter activity
C1N55_RS05550	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C1N55_RS05555	COG4896	Protein conserved in bacteria
C1N55_RS05560	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
C1N55_RS05570	COG0772	Belongs to the SEDS family
C1N55_RS05575	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
C1N55_RS05600	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
C1N55_RS05605	COG3336	cytochrome c oxidase
C1N55_RS05610	COG2322	membrane
C1N55_RS05625	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C1N55_RS05630	COG3679	Belongs to the UPF0342 family
C1N55_RS05635	COG0584	glycerophosphoryl diester phosphodiesterase
C1N55_RS05640	COG4471	UPF0298 protein
C1N55_RS05655	COG0742	ribosomal rna small subunit methyltransferase
C1N55_RS05675	COG3480	Lon protease (S16) C-terminal proteolytic domain
C1N55_RS05685	COG1399	metal-binding, possibly nucleic acid-binding protein
C1N55_RS05695	COG1024	Enoyl-CoA hydratase
C1N55_RS05705	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C1N55_RS05720	COG2001	Belongs to the MraZ family
C1N55_RS05730	COG4839	cell division protein FtsL
C1N55_RS05735	COG0768	penicillin binding
C1N55_RS05740	COG0768	penicillin binding
C1N55_RS05745	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C1N55_RS05750	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
C1N55_RS05755	COG0772	Belongs to the SEDS family
C1N55_RS05760	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
C1N55_RS05765	COG3879	Bacterial protein of unknown function (DUF881)
C1N55_RS05775	COG3856	small basic protein
C1N55_RS05780	COG0849	cell division
C1N55_RS05785	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
C1N55_RS05795	COG1191	sigma factor activity
C1N55_RS05800	COG1191	sigma factor activity
C1N55_RS05810	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
C1N55_RS05815	COG1799	cell septum assembly
C1N55_RS05820	COG0762	integral membrane protein
C1N55_RS05825	COG2302	S4 RNA-binding domain
C1N55_RS05830	COG3599	regulation of cell shape
C1N55_RS05835	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
C1N55_RS05845	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
C1N55_RS05850	COG0564	pseudouridine synthase activity
C1N55_RS05855	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
C1N55_RS05865	COG0540	Belongs to the ATCase OTCase family
C1N55_RS05890	COG0167	dihydroorotate dehydrogenase activity
C1N55_RS05910	COG1293	RNA-binding protein homologous to eukaryotic snRNP
C1N55_RS05915	COG1561	YicC-like family, N-terminal region
C1N55_RS05930	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C1N55_RS05935	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C1N55_RS05940	COG0242	peptide deformylase activity
C1N55_RS05950	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C1N55_RS05950	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C1N55_RS05960	COG0631	protein serine/threonine phosphatase activity
C1N55_RS05965	COG2815	serine threonine protein kinase
C1N55_RS05965	COG0515	serine threonine protein kinase
C1N55_RS05975	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C1N55_RS05980	COG1564	THIamine pyrophosphokinase
C1N55_RS05990	COG0227	Belongs to the bacterial ribosomal protein bL28 family
C1N55_RS05995	COG1302	Protein conserved in bacteria
C1N55_RS06000	COG1461	Dihydroxyacetone kinase
C1N55_RS06005	COG1760	l-serine dehydratase
C1N55_RS06010	COG1760	l-serine dehydratase
C1N55_RS06015	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C1N55_RS06020	COG1349	DNA-binding transcription factor activity
C1N55_RS06020	COG2050	protein possibly involved in aromatic compounds catabolism
C1N55_RS06030	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C1N55_RS06035	COG1028	Short-chain dehydrogenase reductase Sdr
C1N55_RS06040	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C1N55_RS06045	COG0571	ribonuclease III activity
C1N55_RS06050	COG1196	nuclear chromosome segregation
C1N55_RS06055	COG0552	protein localization to endoplasmic reticulum
C1N55_RS06060	COG2814	Major facilitator Superfamily
C1N55_RS06065	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
C1N55_RS06070	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C1N55_RS06080	COG1837	Belongs to the UPF0109 family
C1N55_RS06125	COG2257	FlhB HrpN YscU SpaS Family
C1N55_RS06130	COG0045	succinate-CoA ligase (ADP-forming) activity
C1N55_RS06135	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C1N55_RS06140	COG0758	DNA mediated transformation
C1N55_RS06145	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C1N55_RS06150	COG4974	Belongs to the 'phage' integrase family
C1N55_RS06160	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
C1N55_RS06170	COG1815	bacterial-type flagellum-dependent cell motility
C1N55_RS06175	COG1558	bacterial-type flagellum-dependent cell motility
C1N55_RS06180	COG1677	Flagellar hook-basal body complex protein FliE
C1N55_RS06185	COG1766	The M ring may be actively involved in energy transduction
C1N55_RS06190	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C1N55_RS06200	COG1157	protein secretion by the type III secretion system
C1N55_RS06205	COG2882	bacterial-type flagellum organization
C1N55_RS06220	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
C1N55_RS06230	COG4786	Flagellar basal body rod
C1N55_RS06235	COG1582	Flagellar protein (FlbD)
C1N55_RS06240	COG1580	Controls the rotational direction of flagella during chemotaxis
C1N55_RS06245	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C1N55_RS06250	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C1N55_RS06250	COG1776	CheC inhibitor of MCP methylation
C1N55_RS06255	COG2201	protein-glutamate methylesterase activity
C1N55_RS06260	COG3190	flagellar
C1N55_RS06265	COG1338	Plays a role in the flagellum-specific transport system
C1N55_RS06270	COG1987	bacterial-type flagellum assembly
C1N55_RS06275	COG1684	flagellar biosynthetic protein fliR
C1N55_RS06280	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C1N55_RS06285	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C1N55_RS06290	COG1419	protein localization to endoplasmic reticulum
C1N55_RS06295	COG0455	bacterial-type flagellum organization
C1N55_RS06300	COG2201	protein-glutamate methylesterase activity
C1N55_RS06305	COG0643	Histidine kinase
C1N55_RS06305	COG2198	Histidine kinase
C1N55_RS06310	COG0835	chemotaxis
C1N55_RS06315	COG1776	CheC inhibitor of MCP methylation
C1N55_RS06320	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
C1N55_RS06330	COG1191	sigma factor activity
C1N55_RS06360	COG0233	cytoplasmic translational termination
C1N55_RS06370	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C1N55_RS06375	COG4589	Belongs to the CDS family
C1N55_RS06385	COG0750	zinc metalloprotease
C1N55_RS06395	COG2176	DNA-directed DNA polymerase activity
C1N55_RS06405	COG0195	Participates in both transcription termination and antitermination
C1N55_RS06410	COG2740	Nucleic-acid-binding protein implicated in transcription termination
C1N55_RS06415	COG1358	cellular component organization or biogenesis
C1N55_RS06425	COG1550	Protein conserved in bacteria
C1N55_RS06435	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
C1N55_RS06440	COG0196	riboflavin kinase activity
C1N55_RS06455	COG0577	efflux transmembrane transporter activity
C1N55_RS06460	COG1136	(ABC) transporter
C1N55_RS06465	COG0612	Peptidase, M16
C1N55_RS06480	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C1N55_RS06485	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C1N55_RS06505	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
C1N55_RS06510	COG1674	ftsk spoiiie
C1N55_RS06515	COG2188	Transcriptional regulator
C1N55_RS06520	COG1744	ABC transporter substrate-binding protein PnrA-like
C1N55_RS06525	COG3845	ABC transporter
C1N55_RS06530	COG4603	Belongs to the binding-protein-dependent transport system permease family
C1N55_RS06535	COG1079	Belongs to the binding-protein-dependent transport system permease family
C1N55_RS06540	COG0612	Peptidase, M16
C1N55_RS06545	COG0612	Peptidase, M16
C1N55_RS06550	COG1028	Short-chain dehydrogenase reductase Sdr
C1N55_RS06565	COG1426	Protein conserved in bacteria
C1N55_RS06570	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C1N55_RS06600	COG0477	Major facilitator Superfamily
C1N55_RS06635	COG3944	biosynthesis protein
C1N55_RS06640	COG0489	protein tyrosine kinase activity
C1N55_RS06655	COG0166	Belongs to the GPI family
C1N55_RS06660	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C1N55_RS06675	COG0438	transferase activity, transferring glycosyl groups
C1N55_RS06700	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C1N55_RS06725	COG1716	ATPase activity
C1N55_RS06725	COG5001	Diguanylate cyclase
C1N55_RS06735	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C1N55_RS06760	COG0583	DNA-binding transcription factor activity
C1N55_RS06835	COG0655	NAD(P)H dehydrogenase (quinone) activity
C1N55_RS06840	COG0583	DNA-binding transcription factor activity
C1N55_RS06850	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
C1N55_RS06875	COG2252	PERMEase
C1N55_RS06960	COG0772	Belongs to the SEDS family
C1N55_RS07005	COG5002	protein histidine kinase activity
C1N55_RS07020	COG1408	metallophosphoesterase
C1N55_RS07025	COG4844	belongs to the
C1N55_RS07030	COG2357	RelA SpoT domain protein
C1N55_RS07040	COG2910	NAD(P)H-binding
C1N55_RS07050	COG2816	NAD+ diphosphatase activity
C1N55_RS07080	COG0596	Alpha beta hydrolase
C1N55_RS07105	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
C1N55_RS07105	COG0456	acetyltransferase
C1N55_RS07125	COG2801	Transposase and inactivated derivatives
C1N55_RS07140	COG1733	regulation of RNA biosynthetic process
C1N55_RS07145	COG0702	epimerase
C1N55_RS07190	COG1366	Belongs to the anti-sigma-factor antagonist family
C1N55_RS07195	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C1N55_RS07205	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
C1N55_RS07210	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C1N55_RS07220	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C1N55_RS07245	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C1N55_RS07280	COG3944	biosynthesis protein
C1N55_RS07285	COG0489	protein tyrosine kinase activity
C1N55_RS07290	COG1692	metallophosphoesterase
C1N55_RS07295	COG2359	stage V sporulation protein S
C1N55_RS07300	COG0840	transmembrane signaling receptor activity
C1N55_RS07305	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C1N55_RS07310	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
C1N55_RS07310	COG0674	pyruvate-flavodoxin oxidoreductase activity
C1N55_RS07315	COG1013	pyruvate-flavodoxin oxidoreductase activity
C1N55_RS07345	COG0786	glutamate:sodium symporter activity
C1N55_RS07350	COG0583	DNA-binding transcription factor activity
C1N55_RS07390	COG0840	transmembrane signaling receptor activity
C1N55_RS07415	COG4550	Control of competence regulator ComK, YlbF/YmcA
C1N55_RS07450	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
C1N55_RS07455	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
C1N55_RS07470	COG1923	regulation of RNA biosynthetic process
C1N55_RS07480	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C1N55_RS07485	COG2860	membrane
C1N55_RS07490	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
C1N55_RS07500	COG0789	Transcriptional regulator
C1N55_RS07505	COG0174	glutamine synthetase
C1N55_RS07550	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C1N55_RS07560	COG1459	type II secretion system
C1N55_RS07585	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
C1N55_RS07590	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
C1N55_RS07605	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C1N55_RS07610	COG0789	Transcriptional regulator
C1N55_RS07615	COG1064	alcohol dehydrogenase
C1N55_RS07630	COG3706	GGDEF domain
C1N55_RS07635	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
C1N55_RS07640	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C1N55_RS07650	COG4585	Histidine kinase
C1N55_RS07675	COG3763	UPF0154 protein
C1N55_RS07680	COG1073	alpha beta
C1N55_RS07685	COG1028	Short-chain dehydrogenase reductase Sdr
C1N55_RS07690	COG2610	gluconate transmembrane transporter activity
C1N55_RS07695	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C1N55_RS07700	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
C1N55_RS07705	COG3829	transcription factor binding
C1N55_RS07705	COG3290	protein histidine kinase activity
C1N55_RS07715	COG1113	amino acid transport
C1N55_RS07725	COG0667	Aldo Keto reductase
C1N55_RS07740	COG0735	belongs to the Fur family
C1N55_RS07745	COG4974	Belongs to the 'phage' integrase family
C1N55_RS07755	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
C1N55_RS07775	COG0697	spore germination
C1N55_RS07780	COG0019	diaminopimelate decarboxylase activity
C1N55_RS07785	COG0456	acetyltransferase
C1N55_RS07795	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
C1N55_RS07800	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
C1N55_RS07805	COG1686	Belongs to the peptidase S11 family
C1N55_RS07810	COG1187	pseudouridine synthase activity
C1N55_RS07815	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C1N55_RS07820	COG1333	cytochrome c biogenesis protein
C1N55_RS07825	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C1N55_RS07830	COG0745	RESPONSE REGULATOR receiver
C1N55_RS07835	COG5002	protein histidine kinase activity
C1N55_RS07850	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
C1N55_RS07855	COG0789	Transcriptional regulator
C1N55_RS07860	COG0174	glutamine synthetase
C1N55_RS07865	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C1N55_RS07875	COG4196	transglutaminase domain protein
C1N55_RS07915	COG1141	Ferredoxin
C1N55_RS07920	COG4955	Helix-turn-helix domain
C1N55_RS07925	COG0514	ATP-dependent DNA helicase (RecQ)
C1N55_RS07930	COG1388	LysM domain
C1N55_RS07935	COG1408	metallophosphoesterase
C1N55_RS07940	COG0492	ferredoxin-NADP+ reductase activity
C1N55_RS07970	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C1N55_RS07980	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C1N55_RS07985	COG2188	Transcriptional regulator
C1N55_RS07995	COG0657	acetylesterase activity
C1N55_RS08000	COG2358	TRAP transporter, solute receptor (TAXI family
C1N55_RS08020	COG2267	carboxylic ester hydrolase activity
C1N55_RS08025	COG1960	acyl-CoA dehydrogenase activity
C1N55_RS08050	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C1N55_RS08060	COG1028	Short-chain dehydrogenase reductase Sdr
C1N55_RS08065	COG1028	Short-chain dehydrogenase reductase Sdr
C1N55_RS08075	COG0196	riboflavin kinase activity
C1N55_RS08085	COG3976	FMN-binding domain protein
C1N55_RS08085	COG1053	succinate dehydrogenase
C1N55_RS08090	COG0300	oxidoreductase activity
C1N55_RS08115	COG1960	acyl-CoA dehydrogenase activity
C1N55_RS08130	COG1053	succinate dehydrogenase
C1N55_RS08145	COG2339	peptidase activity
C1N55_RS08150	COG3409	Peptidoglycan-binding domain 1 protein
C1N55_RS08150	COG3773	Cell wall hydrolase
C1N55_RS08160	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
C1N55_RS08175	COG0539	negative regulation of cytoplasmic translation
C1N55_RS08200	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
C1N55_RS08235	COG0105	UTP biosynthetic process
C1N55_RS08245	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
C1N55_RS08260	COG4401	Chorismate mutase type I
C1N55_RS08270	COG0287	Prephenate dehydrogenase
C1N55_RS08280	COG0457	Tetratricopeptide repeat
C1N55_RS08285	COG5582	Belongs to the UPF0302 family
C1N55_RS08295	COG0723	plastoquinol--plastocyanin reductase activity
C1N55_RS08300	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
C1N55_RS08310	COG4347	Protein of unknown function (DUF1405)
C1N55_RS08315	COG2738	Putative neutral zinc metallopeptidase
C1N55_RS08325	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C1N55_RS08340	COG0438	transferase activity, transferring glycosyl groups
C1N55_RS08345	COG0617	tRNA 3'-terminal CCA addition
C1N55_RS08350	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
C1N55_RS08350	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
C1N55_RS08365	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
C1N55_RS08370	COG1199	ATP-dependent helicase activity
C1N55_RS08370	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C1N55_RS08385	COG0017	Asparaginyl-tRNA synthetase
C1N55_RS08390	COG3935	DnaD domain protein
C1N55_RS08395	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C1N55_RS08405	COG4499	WXG100 protein secretion system (Wss), protein YukC
C1N55_RS08405	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C1N55_RS08425	COG1111	helicase
C1N55_RS08425	COG1205	dead DEAH box helicase
C1N55_RS08430	COG3359	exonuclease
C1N55_RS08435	COG3599	regulation of cell shape
C1N55_RS08450	COG0116	Belongs to the methyltransferase superfamily
C1N55_RS08455	COG1199	ATP-dependent helicase activity
C1N55_RS08490	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C1N55_RS08500	COG1028	Short-chain dehydrogenase reductase Sdr
C1N55_RS08510	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C1N55_RS08515	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C1N55_RS08525	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
C1N55_RS08545	COG0281	malic enzyme
C1N55_RS08555	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C1N55_RS08560	COG1671	Belongs to the UPF0178 family
C1N55_RS08570	COG3706	GGDEF domain
C1N55_RS08590	COG0328	RNA-DNA hybrid ribonuclease activity
C1N55_RS08610	COG1405	negative regulation of cell septum assembly
C1N55_RS08610	COG3012	SEC-C Motif Domain Protein
C1N55_RS08620	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C1N55_RS08640	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C1N55_RS08645	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C1N55_RS08655	COG2759	Belongs to the formate--tetrahydrofolate ligase family
C1N55_RS08660	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C1N55_RS08665	COG1132	(ABC) transporter
C1N55_RS08670	COG1609	Transcriptional regulator
C1N55_RS08675	COG1131	(ABC) transporter
C1N55_RS08690	COG0840	transmembrane signaling receptor activity
C1N55_RS08695	COG1609	Transcriptional regulator
C1N55_RS08700	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C1N55_RS08705	COG1869	D-ribose catabolic process
C1N55_RS08715	COG1172	Belongs to the binding-protein-dependent transport system permease family
C1N55_RS08720	COG1879	ABC-type sugar transport system periplasmic component
C1N55_RS08725	COG2259	Doxx family
C1N55_RS08730	COG1418	mRNA catabolic process
C1N55_RS08740	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
C1N55_RS08750	COG1473	amidohydrolase
C1N55_RS08755	COG0488	(ABC) transporter
C1N55_RS08760	COG1413	lyase activity
C1N55_RS08765	COG0697	spore germination
C1N55_RS08795	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C1N55_RS08830	COG2720	vancomycin resistance protein
C1N55_RS08835	COG0384	phenazine biosynthesis protein PhzF
C1N55_RS08850	COG2608	mercury ion transmembrane transporter activity
C1N55_RS08855	COG2217	Heavy metal translocating P-type atpase
C1N55_RS08860	COG0726	polysaccharide deacetylase
C1N55_RS08885	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C1N55_RS08885	COG0551	DNA topoisomerase type I activity
C1N55_RS08930	COG0527	aspartate kinase activity
C1N55_RS08950	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C1N55_RS08955	COG1045	serine acetyltransferase
C1N55_RS08975	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C1N55_RS09000	COG0492	ferredoxin-NADP+ reductase activity
C1N55_RS09015	COG4895	conserved protein (DUF2196)
C1N55_RS09030	COG0640	Transcriptional regulator
C1N55_RS09055	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
C1N55_RS09065	COG0720	synthase
C1N55_RS09070	COG0602	queuosine metabolic process
C1N55_RS09090	COG3181	Tripartite tricarboxylate transporter family receptor
C1N55_RS09100	COG2721	sulfolactate sulfo-lyase activity
C1N55_RS09105	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C1N55_RS09115	COG2271	Major facilitator Superfamily
C1N55_RS09125	COG2186	Transcriptional regulator
C1N55_RS09140	COG0840	transmembrane signaling receptor activity
C1N55_RS09155	COG2814	Major facilitator Superfamily
C1N55_RS09200	COG1113	amino acid transport
C1N55_RS09205	COG1280	lysine exporter protein (LysE YggA)
C1N55_RS09220	COG1131	(ABC) transporter
C1N55_RS09230	COG2814	Major facilitator Superfamily
C1N55_RS09240	COG2521	methyltransferase
C1N55_RS09240	COG2136	Putative SAM-dependent methyltransferase
C1N55_RS09245	COG1126	abc transporter atp-binding protein
C1N55_RS09250	COG0765	amino acid transport
C1N55_RS09255	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C1N55_RS09275	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
C1N55_RS09285	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
C1N55_RS09290	COG0725	ABC transporter, periplasmic molybdate-binding protein
C1N55_RS09295	COG4149	molybdate abc transporter
C1N55_RS09300	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C1N55_RS09305	COG0303	'Molybdopterin
C1N55_RS09310	COG0314	molybdopterin synthase activity
C1N55_RS09315	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
C1N55_RS09325	COG0315	cyclic pyranopterin monophosphate synthase activity
C1N55_RS09330	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
C1N55_RS09335	COG1529	Aldehyde oxidase and xanthine dehydrogenase
C1N55_RS09340	COG2080	2 iron, 2 sulfur cluster binding
C1N55_RS09345	COG3706	GGDEF domain
C1N55_RS09355	COG0488	(ABC) transporter
C1N55_RS09365	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C1N55_RS09390	COG1585	Membrane protein implicated in regulation of membrane protease activity
C1N55_RS09395	COG2268	Band 7 protein
C1N55_RS09405	COG3858	chitin binding
C1N55_RS09425	COG5002	protein histidine kinase activity
C1N55_RS09430	COG0577	efflux transmembrane transporter activity
C1N55_RS09430	COG1136	(ABC) transporter
C1N55_RS09445	COG1033	growth of symbiont in host cell
C1N55_RS09445	COG2409	Drug exporters of the RND superfamily
C1N55_RS09450	COG1272	protein, Hemolysin III
C1N55_RS09455	COG1307	EDD domain protein, DegV family
C1N55_RS09475	COG2755	lipolytic protein G-D-S-L family
C1N55_RS09520	COG0813	purine-nucleoside phosphorylase activity
C1N55_RS09525	COG3409	Peptidoglycan-binding domain 1 protein
C1N55_RS09525	COG0793	Belongs to the peptidase S41A family
C1N55_RS09530	COG0523	cobalamin synthesis protein
C1N55_RS09535	COG2340	Cysteine-rich secretory protein family
C1N55_RS09550	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
C1N55_RS09560	COG0745	RESPONSE REGULATOR receiver
C1N55_RS09565	COG5002	protein histidine kinase activity
C1N55_RS09570	COG0567	Dehydrogenase, E1 component
C1N55_RS09575	COG0508	dehydrogenase complex catalyzes the overall conversion of
C1N55_RS09580	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C1N55_RS09585	COG0765	amino acid transport
C1N55_RS09600	COG3853	Toxic anion resistance protein (TelA)
C1N55_RS09615	COG1278	Cold shock
C1N55_RS09625	COG0488	(ABC) transporter
C1N55_RS09630	COG0514	ATP-dependent DNA helicase (RecQ)
C1N55_RS09635	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C1N55_RS09645	COG0628	permease
C1N55_RS09650	COG0436	Aminotransferase
C1N55_RS09660	COG1024	Enoyl-CoA hydratase
C1N55_RS09690	COG3300	MHYT domain
C1N55_RS09690	COG5001	Diguanylate cyclase
C1N55_RS09705	COG3853	Toxic anion resistance protein (TelA)
C1N55_RS09715	COG0583	DNA-binding transcription factor activity
C1N55_RS09725	COG0583	DNA-binding transcription factor activity
C1N55_RS09750	COG0640	Transcriptional regulator
C1N55_RS09755	COG0583	DNA-binding transcription factor activity
C1N55_RS09760	COG0697	spore germination
C1N55_RS09765	COG2323	membrane
C1N55_RS09775	COG0640	Transcriptional regulator
C1N55_RS09815	COG0456	acetyltransferase
C1N55_RS09825	COG0346	lactoylglutathione lyase activity
C1N55_RS09830	COG1937	Protein conserved in bacteria
C1N55_RS09835	COG1054	Belongs to the UPF0176 family
C1N55_RS09845	COG0425	Belongs to the sulfur carrier protein TusA family
C1N55_RS09845	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C1N55_RS09850	COG2210	Belongs to the sulfur carrier protein TusA family
C1N55_RS09855	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C1N55_RS09855	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C1N55_RS09860	COG0425	Belongs to the sulfur carrier protein TusA family
C1N55_RS09865	COG0730	response to heat
C1N55_RS09880	COG0745	RESPONSE REGULATOR receiver
C1N55_RS09890	COG1027	Aspartate ammonia-lyase
C1N55_RS09905	COG0028	Belongs to the TPP enzyme family
C1N55_RS09910	COG0583	DNA-binding transcription factor activity
C1N55_RS09920	COG0006	proline dipeptidase activity
C1N55_RS09930	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C1N55_RS09945	COG2329	Antibiotic biosynthesis monooxygenase
C1N55_RS09960	COG0656	L-ascorbic acid biosynthetic process
C1N55_RS09970	COG0656	L-ascorbic acid biosynthetic process
C1N55_RS09980	COG1619	proteins homologs of microcin C7 resistance protein MccF
C1N55_RS10015	COG1028	Short-chain dehydrogenase reductase Sdr
C1N55_RS10030	COG1335	isochorismatase
C1N55_RS10045	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
C1N55_RS10050	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C1N55_RS10055	COG0183	Belongs to the thiolase family
C1N55_RS10065	COG2031	fatty acid transporter
C1N55_RS10080	COG0583	DNA-binding transcription factor activity
C1N55_RS10095	COG0577	efflux transmembrane transporter activity
C1N55_RS10100	COG1136	(ABC) transporter
C1N55_RS10110	COG5002	protein histidine kinase activity
C1N55_RS10150	COG2814	Major facilitator Superfamily
C1N55_RS10155	COG2076	Multidrug Resistance protein
C1N55_RS10160	COG2076	Multidrug Resistance protein
C1N55_RS10165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C1N55_RS10170	COG2808	Putative FMN-binding domain
C1N55_RS10180	COG0583	DNA-binding transcription factor activity
C1N55_RS10185	COG0460	homoserine dehydrogenase
C1N55_RS10200	COG1846	Transcriptional regulator
C1N55_RS10205	COG0456	acetyltransferase
C1N55_RS10215	COG0583	DNA-binding transcription factor activity
C1N55_RS10220	COG0427	acetyl-CoA hydrolase
C1N55_RS10235	COG0425	Belongs to the sulfur carrier protein TusA family
C1N55_RS10240	COG2210	Belongs to the sulfur carrier protein TusA family
C1N55_RS10245	COG0662	Cupin 2, conserved barrel domain protein
C1N55_RS10250	COG1937	Protein conserved in bacteria
C1N55_RS10255	COG1937	Protein conserved in bacteria
C1N55_RS10260	COG1054	Belongs to the UPF0176 family
C1N55_RS10265	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C1N55_RS10270	COG0425	Belongs to the sulfur carrier protein TusA family
C1N55_RS10270	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C1N55_RS10275	COG2210	Belongs to the sulfur carrier protein TusA family
C1N55_RS10280	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C1N55_RS10280	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C1N55_RS10285	COG0425	Belongs to the sulfur carrier protein TusA family
C1N55_RS10290	COG0730	response to heat
C1N55_RS10300	COG2409	Drug exporters of the RND superfamily
C1N55_RS10310	COG4974	Belongs to the 'phage' integrase family
C1N55_RS10315	COG1388	LysM domain
C1N55_RS10320	COG0745	RESPONSE REGULATOR receiver
C1N55_RS10325	COG5002	protein histidine kinase activity
C1N55_RS10335	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C1N55_RS10340	COG0697	spore germination
C1N55_RS10345	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C1N55_RS10350	COG0187	DNA topoisomerase II activity
C1N55_RS10355	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
C1N55_RS10360	COG4841	protein insertion into membrane
C1N55_RS10370	COG0655	NAD(P)H dehydrogenase (quinone) activity
C1N55_RS10375	COG1028	Short-chain dehydrogenase reductase Sdr
C1N55_RS10380	COG1574	metal-dependent hydrolase with the TIM-barrel fold
C1N55_RS10385	COG2720	vancomycin resistance protein
C1N55_RS10405	COG0840	transmembrane signaling receptor activity
C1N55_RS10410	COG2720	vancomycin resistance protein
C1N55_RS10435	COG0739	heme binding
C1N55_RS10440	COG2153	protein acetylation
C1N55_RS10450	COG1090	epimerase
C1N55_RS10485	COG3069	C4-dicarboxylate transmembrane transporter activity
C1N55_RS10495	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C1N55_RS10500	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
C1N55_RS10505	COG1028	Short-chain dehydrogenase reductase Sdr
C1N55_RS10510	COG1250	3-hydroxyacyl-CoA dehydrogenase
C1N55_RS10515	COG2610	gluconate transmembrane transporter activity
C1N55_RS10520	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C1N55_RS10540	COG0824	Thioesterase
C1N55_RS10555	COG0010	Belongs to the arginase family
C1N55_RS10560	COG1228	amidohydrolase
C1N55_RS10565	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
C1N55_RS10570	COG2986	histidine ammonia-lyase
C1N55_RS10595	COG0322	excinuclease ABC activity
C1N55_RS10605	COG4145	pantothenate transmembrane transporter activity
C1N55_RS10630	COG0737	Belongs to the 5'-nucleotidase family
C1N55_RS10635	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
C1N55_RS10655	COG0535	radical SAM domain protein
C1N55_RS10670	COG0066	3-isopropylmalate dehydratase activity
C1N55_RS10695	COG0440	acetolactate synthase activity
C1N55_RS10700	COG0028	Belongs to the TPP enzyme family
C1N55_RS10705	COG0129	dihydroxy-acid dehydratase activity
C1N55_RS10710	COG2261	transglycosylase associated protein
C1N55_RS10725	COG0626	cystathionine gamma-synthase activity
C1N55_RS10730	COG0517	IMP dehydrogenase activity
C1N55_RS10735	COG1999	signal sequence binding
C1N55_RS10760	COG4846	Membrane protein involved in cytochrome C biogenesis
C1N55_RS10765	COG2201	protein-glutamate methylesterase activity
C1N55_RS10770	COG0785	Cytochrome C biogenesis protein
C1N55_RS10775	COG2962	Rard protein
C1N55_RS10780	COG1132	(ABC) transporter
C1N55_RS10785	COG1132	(ABC) transporter
C1N55_RS10795	COG1668	transmembrane transport
C1N55_RS10800	COG4152	abc transporter atp-binding protein
C1N55_RS10815	COG0657	acetylesterase activity
C1N55_RS10830	COG3853	Toxic anion resistance protein (TelA)
C1N55_RS10835	COG1028	Short-chain dehydrogenase reductase Sdr
C1N55_RS10865	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
C1N55_RS10880	COG0840	transmembrane signaling receptor activity
C1N55_RS10900	COG0427	acetyl-CoA hydrolase
C1N55_RS10935	COG0640	Transcriptional regulator
C1N55_RS10945	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C1N55_RS10950	COG0579	oxidoreductase
C1N55_RS10955	COG0702	epimerase
C1N55_RS10965	COG2217	Heavy metal translocating P-type atpase
C1N55_RS10970	COG0788	formyltetrahydrofolate deformylase activity
C1N55_RS10980	COG0512	Glutamine amidotransferase of anthranilate synthase
C1N55_RS11015	COG0183	Belongs to the thiolase family
C1N55_RS11035	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C1N55_RS11040	COG0747	negative chemotaxis
C1N55_RS11045	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C1N55_RS11060	COG0318	PFAM AMP-dependent synthetase and ligase
C1N55_RS11080	COG1960	acyl-CoA dehydrogenase activity
C1N55_RS11085	COG0508	dehydrogenase complex catalyzes the overall conversion of
C1N55_RS11085	COG0596	Alpha beta hydrolase
C1N55_RS11090	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C1N55_RS11100	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C1N55_RS11110	COG1845	cytochrome c oxidase, subunit III
C1N55_RS11115	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
C1N55_RS11130	COG1957	nucleoside hydrolase
C1N55_RS11135	COG0778	Nitroreductase
C1N55_RS11160	COG0860	N-Acetylmuramoyl-L-alanine amidase
C1N55_RS11175	COG2146	nitrite reductase [NAD(P)H] activity
C1N55_RS11180	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C1N55_RS11185	COG1587	Uroporphyrinogen-III synthase
C1N55_RS11195	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
C1N55_RS11210	COG2155	Conserved Protein
C1N55_RS11230	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C1N55_RS11280	COG2258	MOSC domain
C1N55_RS11285	COG0183	Belongs to the thiolase family
C1N55_RS11300	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C1N55_RS11325	COG1253	flavin adenine dinucleotide binding
C1N55_RS11330	COG0789	Transcriptional regulator
C1N55_RS11335	COG2368	4-hydroxyphenylacetate
C1N55_RS11350	COG1846	Transcriptional regulator
C1N55_RS11365	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
C1N55_RS11370	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
C1N55_RS11385	COG0165	Argininosuccinate lyase
C1N55_RS11390	COG0137	argininosuccinate synthase activity
C1N55_RS11395	COG0300	oxidoreductase activity
C1N55_RS11410	COG1959	2 iron, 2 sulfur cluster binding
C1N55_RS11420	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C1N55_RS11425	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C1N55_RS11440	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C1N55_RS11450	COG1054	Belongs to the UPF0176 family
C1N55_RS11455	COG1268	BioY protein
C1N55_RS11470	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C1N55_RS11470	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C1N55_RS11480	COG1307	EDD domain protein, DegV family
C1N55_RS11500	COG0004	ammonium transporteR
C1N55_RS11505	COG3583	domain protein
C1N55_RS11505	COG3584	3D domain protein
C1N55_RS11545	COG1119	ATPase activity
C1N55_RS11555	COG1289	transmembrane transporter activity
C1N55_RS11560	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C1N55_RS11580	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C1N55_RS11590	COG0586	Pfam SNARE associated Golgi protein
C1N55_RS11600	COG2195	Cleaves the N-terminal amino acid of tripeptides
C1N55_RS11625	COG0805	protein transport
C1N55_RS11635	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C1N55_RS11640	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C1N55_RS11645	COG0346	lactoylglutathione lyase activity
C1N55_RS11650	COG4129	membrane
C1N55_RS11660	COG1703	isobutyryl-CoA mutase activity
C1N55_RS11665	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
C1N55_RS11665	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
C1N55_RS11675	COG0508	dehydrogenase complex catalyzes the overall conversion of
C1N55_RS11680	COG0022	dehydrogenase e1 component
C1N55_RS11685	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C1N55_RS11690	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C1N55_RS11705	COG0584	glycerophosphoryl diester phosphodiesterase
C1N55_RS11715	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
C1N55_RS11720	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
C1N55_RS11725	COG1984	allophanate hydrolase subunit 2
C1N55_RS11740	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C1N55_RS11750	COG0750	zinc metalloprotease
C1N55_RS11755	COG0497	DNA recombination
C1N55_RS11760	COG1438	arginine binding
C1N55_RS11765	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
C1N55_RS11775	COG0142	geranyltranstransferase activity
C1N55_RS11805	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
C1N55_RS11815	COG1302	Protein conserved in bacteria
C1N55_RS11820	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C1N55_RS11825	COG0439	Biotin carboxylase
C1N55_RS11830	COG0511	ligase activity, forming carbon-carbon bonds
C1N55_RS11865	COG0006	proline dipeptidase activity
C1N55_RS11870	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
C1N55_RS11880	COG3872	metal-dependent enzyme
C1N55_RS11885	COG0730	response to heat
C1N55_RS11900	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C1N55_RS11920	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
C1N55_RS11945	COG4537	Required for transformation and DNA binding
C1N55_RS11950	COG1459	type II secretion system
C1N55_RS11955	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C1N55_RS11970	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C1N55_RS11980	COG1368	sulfuric ester hydrolase activity
C1N55_RS11990	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C1N55_RS11995	COG0267	Belongs to the bacterial ribosomal protein bL33 family
C1N55_RS12010	COG0583	DNA-binding transcription factor activity
C1N55_RS12015	COG2814	Major facilitator Superfamily
C1N55_RS12020	COG0386	Belongs to the glutathione peroxidase family
C1N55_RS12030	COG1595	DNA-templated transcription, initiation
C1N55_RS12040	COG0512	Glutamine amidotransferase of anthranilate synthase
C1N55_RS12040	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C1N55_RS12045	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C1N55_RS12055	COG0704	Plays a role in the regulation of phosphate uptake
C1N55_RS12060	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C1N55_RS12065	COG0581	inorganic phosphate transmembrane transporter activity
C1N55_RS12070	COG0573	inorganic phosphate transmembrane transporter activity
C1N55_RS12075	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C1N55_RS12080	COG0768	penicillin binding
C1N55_RS12095	COG1131	(ABC) transporter
C1N55_RS12100	COG2197	response regulator
C1N55_RS12105	COG4585	Histidine kinase
C1N55_RS12115	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C1N55_RS12120	COG0501	Belongs to the peptidase M48B family
C1N55_RS12125	COG3871	stress protein (general stress protein 26)
C1N55_RS12130	COG1752	Esterase of the alpha-beta hydrolase superfamily
C1N55_RS12145	COG2839	Protein conserved in bacteria
C1N55_RS12165	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
C1N55_RS12170	COG5001	Diguanylate cyclase
C1N55_RS12185	COG1823	symporter activity
C1N55_RS12215	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
C1N55_RS12235	COG0735	belongs to the Fur family
C1N55_RS12240	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C1N55_RS12245	COG1121	(ABC) transporter
C1N55_RS12255	COG2027	D-alanyl-D-alanine carboxypeptidase
C1N55_RS12265	COG0513	Belongs to the DEAD box helicase family
C1N55_RS12285	COG3290	protein histidine kinase activity
C1N55_RS12290	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
C1N55_RS12295	COG1301	dicarboxylic acid transport
C1N55_RS12305	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
C1N55_RS12310	COG2384	SAM-dependent methyltransferase
C1N55_RS12320	COG1960	acyl-CoA dehydrogenase activity
C1N55_RS12330	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C1N55_RS12335	COG0358	DNA primase activity
C1N55_RS12345	COG0517	IMP dehydrogenase activity
C1N55_RS12360	COG1381	Involved in DNA repair and RecF pathway recombination
C1N55_RS12375	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C1N55_RS12385	COG1480	7TM receptor with intracellular HD hydrolase
C1N55_RS12390	COG1702	phosphate starvation-inducible protein PhoH
C1N55_RS12410	COG4864	UPF0365 protein
C1N55_RS12415	COG1030	water channel activity
C1N55_RS12435	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C1N55_RS12440	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C1N55_RS12445	COG2264	protein methyltransferase activity
C1N55_RS12470	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C1N55_RS12480	COG0481	GTPase activity
C1N55_RS12490	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
C1N55_RS12510	COG1466	dna polymerase III delta subunit
C1N55_RS12520	COG2333	competence protein COMEC
C1N55_RS12520	COG0658	competence protein
C1N55_RS12525	COG2131	deaminase
C1N55_RS12530	COG1596	polysaccharide export
C1N55_RS12530	COG1555	photosystem II stabilization
C1N55_RS12535	COG2226	methyltransferase
C1N55_RS12540	COG0799	negative regulation of ribosome biogenesis
C1N55_RS12545	COG1713	HD superfamily hydrolase involved in NAD metabolism
C1N55_RS12550	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
C1N55_RS12555	COG1534	Rna-binding protein
C1N55_RS12565	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
C1N55_RS12570	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
C1N55_RS12575	COG0688	phosphatidylethanolamine metabolic process
C1N55_RS12580	COG1183	phosphatidylcholine synthase activity
C1N55_RS12605	COG0572	uridine kinase
C1N55_RS12610	COG0826	peptidase U32
C1N55_RS12615	COG0826	peptidase U32
C1N55_RS12620	COG4122	O-methyltransferase activity
C1N55_RS12625	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C1N55_RS12635	COG3906	Belongs to the UPF0473 family
C1N55_RS12640	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
C1N55_RS12645	COG4472	Bacterial protein of unknown function (DUF965)
C1N55_RS12660	COG0861	Integral membrane protein TerC family
C1N55_RS12665	COG2814	Major facilitator Superfamily
C1N55_RS12670	COG4326	sporulation control protein
C1N55_RS12685	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C1N55_RS12690	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
C1N55_RS12695	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C1N55_RS12710	COG1104	cysteine desulfurase activity
C1N55_RS12715	COG1959	2 iron, 2 sulfur cluster binding
C1N55_RS12720	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C1N55_RS12755	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
C1N55_RS12780	COG4991	sh3 domain protein
C1N55_RS12780	COG3103	Sh3 type 3 domain protein
C1N55_RS12780	COG0860	N-Acetylmuramoyl-L-alanine amidase
C1N55_RS12790	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C1N55_RS12805	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
C1N55_RS12805	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C1N55_RS12810	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C1N55_RS12810	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C1N55_RS12820	COG2244	polysaccharide biosynthetic process
C1N55_RS12825	COG2323	membrane
C1N55_RS12830	COG1862	Preprotein translocase
C1N55_RS12865	COG1827	regulation of RNA biosynthetic process
C1N55_RS12875	COG0077	Prephenate dehydratase
C1N55_RS12920	COG2894	cell division
C1N55_RS12935	COG1792	Involved in formation and maintenance of cell shape
C1N55_RS12940	COG1077	Cell shape determining protein MreB Mrl
C1N55_RS12945	COG2003	Belongs to the UPF0758 family
C1N55_RS12950	COG0424	maF-like protein
C1N55_RS12960	COG0285	dihydrofolate synthase activity
C1N55_RS12965	COG0285	dihydrofolate synthase activity
C1N55_RS12985	COG0113	porphobilinogen synthase activity
C1N55_RS13000	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C1N55_RS13010	COG0218	Necessary for normal cell division and for the maintenance of normal septation
C1N55_RS13030	COG0457	Tetratricopeptide repeat
C1N55_RS13030	COG1477	protein flavinylation
C1N55_RS13045	COG1695	Transcriptional regulator
C1N55_RS13050	COG1028	Short-chain dehydrogenase reductase Sdr
C1N55_RS13060	COG1272	protein, Hemolysin III
C1N55_RS13065	COG2223	nitrite transmembrane transporter activity
C1N55_RS13070	COG0589	response to stress
C1N55_RS13085	COG2367	Beta-lactamase
C1N55_RS13090	COG1619	proteins homologs of microcin C7 resistance protein MccF
C1N55_RS13095	COG4608	Belongs to the ABC transporter superfamily
C1N55_RS13100	COG0444	Belongs to the ABC transporter superfamily
C1N55_RS13105	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C1N55_RS13110	COG0601	transmembrane transport
C1N55_RS13115	COG4166	transmembrane transport
C1N55_RS13120	COG4948	Mandelate Racemase Muconate Lactonizing
C1N55_RS13130	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
C1N55_RS13165	COG1114	Component of the transport system for branched-chain amino acids
C1N55_RS13175	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C1N55_RS13185	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C1N55_RS13210	COG0492	ferredoxin-NADP+ reductase activity
C1N55_RS13215	COG1802	Transcriptional regulator
C1N55_RS13225	COG3655	Transcriptional regulator
C1N55_RS13260	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
C1N55_RS13275	COG1051	belongs to the nudix hydrolase family
C1N55_RS13360	COG0860	N-Acetylmuramoyl-L-alanine amidase
C1N55_RS13365	COG4824	toxin secretion phage lysis holin
C1N55_RS13480	COG2369	cell adhesion
C1N55_RS13490	COG1783	phage Terminase large subunit
C1N55_RS13495	COG3728	DNA packaging
C1N55_RS13495	COG5484	DNA packaging
C1N55_RS13535	COG3331	DNA recombination
C1N55_RS13575	COG0629	single-stranded DNA binding
C1N55_RS13605	COG1484	DNA-dependent DNA replication
C1N55_RS13630	COG2002	toxin-antitoxin pair type II binding
C1N55_RS13660	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C1N55_RS13685	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
C1N55_RS13695	COG1846	Transcriptional regulator
C1N55_RS13700	COG2197	response regulator
C1N55_RS13705	COG0824	Thioesterase
C1N55_RS13710	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C1N55_RS13715	COG1053	succinate dehydrogenase
C1N55_RS13720	COG2009	succinate dehydrogenase
C1N55_RS13725	COG1719	4-vinyl reductase, 4VR
C1N55_RS13740	COG3118	belongs to the thioredoxin family
C1N55_RS13745	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
C1N55_RS13750	COG2086	electron transfer activity
C1N55_RS13755	COG1024	Enoyl-CoA hydratase
C1N55_RS13760	COG1309	transcriptional regulator
C1N55_RS13765	COG0318	PFAM AMP-dependent synthetase and ligase
C1N55_RS13770	COG3766	membrane
C1N55_RS13780	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
C1N55_RS13780	COG1796	DNA polymerase
C1N55_RS13800	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C1N55_RS13815	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C1N55_RS13815	COG0072	phenylalanine-tRNA ligase activity
C1N55_RS13825	COG0840	transmembrane signaling receptor activity
C1N55_RS13830	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C1N55_RS13835	COG1104	cysteine desulfurase activity
C1N55_RS13840	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
C1N55_RS13845	COG0157	Belongs to the NadC ModD family
C1N55_RS13850	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
C1N55_RS13875	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
C1N55_RS13880	COG1363	Peptidase, m42
C1N55_RS13900	COG3326	Membrane
C1N55_RS13915	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
C1N55_RS13920	COG0438	transferase activity, transferring glycosyl groups
C1N55_RS13925	COG0561	phosphatase activity
C1N55_RS13935	COG1484	DNA-dependent DNA replication
C1N55_RS13940	COG3611	Membrane attachment protein
C1N55_RS13950	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C1N55_RS13960	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
C1N55_RS13965	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C1N55_RS13965	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C1N55_RS13990	COG0395	ABC-type sugar transport system, permease component
C1N55_RS13995	COG4209	transmembrane transport
C1N55_RS14010	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C1N55_RS14015	COG3842	ATPase activity
C1N55_RS14020	COG0330	HflC and HflK could
C1N55_RS14025	COG0330	HflC and HflK could
C1N55_RS14030	COG5002	protein histidine kinase activity
C1N55_RS14035	COG0745	RESPONSE REGULATOR receiver
C1N55_RS14050	COG0538	isocitrate dehydrogenase activity
C1N55_RS14055	COG0372	Belongs to the citrate synthase family
C1N55_RS14065	COG3030	protein affecting phage T7 exclusion by the F plasmid
C1N55_RS14080	COG0825	malonyl-CoA metabolic process
C1N55_RS14090	COG2186	Transcriptional regulator
C1N55_RS14095	COG0587	DNA-directed DNA polymerase activity
C1N55_RS14100	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
C1N55_RS14110	COG4109	DRTGG domain
C1N55_RS14120	COG0006	proline dipeptidase activity
C1N55_RS14140	COG0559	Belongs to the binding-protein-dependent transport system permease family
C1N55_RS14145	COG0683	leucine binding
C1N55_RS14155	COG0589	response to stress
C1N55_RS14160	COG0827	DNA restriction-modification system
C1N55_RS14165	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
C1N55_RS14170	COG1714	RDD family
C1N55_RS14175	COG0616	signal peptide processing
C1N55_RS14180	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C1N55_RS14205	COG1104	cysteine desulfurase activity
C1N55_RS14210	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
C1N55_RS14215	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
C1N55_RS14220	COG1956	GAF domain-containing protein
C1N55_RS14225	COG2199	diguanylate cyclase activity
C1N55_RS14225	COG2203	Gaf domain
C1N55_RS14235	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C1N55_RS14250	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
C1N55_RS14255	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
C1N55_RS14260	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
C1N55_RS14265	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C1N55_RS14270	COG0454	-acetyltransferase
C1N55_RS14275	COG0517	IMP dehydrogenase activity
C1N55_RS14280	COG0123	including yeast histone deacetylase and acetoin utilization protein
C1N55_RS14290	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
C1N55_RS14290	COG1605	Chorismate mutase
C1N55_RS14295	COG0849	cell division
C1N55_RS14300	COG4980	gas vesicle protein
C1N55_RS14305	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
C1N55_RS14315	COG1674	ftsk spoiiie
C1N55_RS14320	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C1N55_RS14335	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
C1N55_RS14340	COG1363	Peptidase, m42
C1N55_RS14350	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C1N55_RS14360	COG1597	lipid kinase activity
C1N55_RS14375	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C1N55_RS14380	COG1349	DNA-binding transcription factor activity
C1N55_RS14385	COG1187	pseudouridine synthase activity
C1N55_RS14390	COG2244	polysaccharide biosynthetic process
C1N55_RS14395	COG2081	HI0933 family
C1N55_RS14410	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C1N55_RS14435	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
C1N55_RS14440	COG2814	Major facilitator Superfamily
C1N55_RS14450	COG2814	Major facilitator Superfamily
C1N55_RS14455	COG1242	4 iron, 4 sulfur cluster binding
C1N55_RS14460	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
C1N55_RS14465	COG1115	amino acid carrier protein
C1N55_RS14470	COG2267	carboxylic ester hydrolase activity
C1N55_RS14475	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C1N55_RS14485	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
C1N55_RS14495	COG1506	peptidase
C1N55_RS14500	COG0494	nUDIX hydrolase
C1N55_RS14510	COG0783	Belongs to the Dps family
C1N55_RS14525	COG0318	PFAM AMP-dependent synthetase and ligase
C1N55_RS14530	COG3706	GGDEF domain
C1N55_RS14540	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
C1N55_RS14545	COG0596	Alpha beta hydrolase
C1N55_RS14555	COG1169	isochorismate synthase
C1N55_RS14565	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C1N55_RS14790	COG1285	pathogenesis
C1N55_RS14800	COG1979	alcohol dehydrogenase
C1N55_RS14810	COG1012	belongs to the aldehyde dehydrogenase family
C1N55_RS14815	COG3829	transcription factor binding
C1N55_RS14820	COG1098	S1 RNA binding domain
C1N55_RS14825	COG1396	sequence-specific DNA binding
C1N55_RS14835	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
C1N55_RS14845	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C1N55_RS14850	COG2814	Major facilitator Superfamily
C1N55_RS14855	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C1N55_RS14865	COG2111	Na H antiporter
C1N55_RS14865	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C1N55_RS14870	COG2111	Na H antiporter
C1N55_RS14875	COG1006	Multisubunit Na H antiporter MnhC subunit
C1N55_RS14880	COG0651	ATP synthesis coupled electron transport
C1N55_RS14885	COG1863	multisubunit Na H antiporter MnhE subunit
C1N55_RS14890	COG2212	antiporter activity
C1N55_RS14895	COG1320	monovalent cation:proton antiporter activity
C1N55_RS14905	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
C1N55_RS14910	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
C1N55_RS14925	COG0316	Belongs to the HesB IscA family
C1N55_RS14935	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
C1N55_RS14940	COG4837	Protein of unknown function (DUF1462)
C1N55_RS14945	COG1252	NADH dehydrogenase
C1N55_RS14950	COG4844	belongs to the
C1N55_RS14955	COG0647	UMP catabolic process
C1N55_RS14960	COG2445	Protein of unknown function DUF86
C1N55_RS14970	COG2814	Major facilitator Superfamily
C1N55_RS14980	COG4470	Protein conserved in bacteria
C1N55_RS15000	COG0737	Belongs to the 5'-nucleotidase family
C1N55_RS15005	COG0730	response to heat
C1N55_RS15010	COG1801	Protein of unknown function DUF72
C1N55_RS15020	COG0431	NADPH-dependent FMN reductase
C1N55_RS15030	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C1N55_RS15045	COG0196	riboflavin kinase activity
C1N55_RS15055	COG4208	sulfate ABC transporter
C1N55_RS15065	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
C1N55_RS15080	COG0529	Catalyzes the synthesis of activated sulfate
C1N55_RS15095	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
C1N55_RS15110	COG0719	Fe-S assembly protein
C1N55_RS15115	COG0822	iron-sulfur transferase activity
C1N55_RS15120	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C1N55_RS15125	COG0719	Fe-S assembly protein
C1N55_RS15130	COG0396	ATPase activity
C1N55_RS15135	COG0493	'glutamate synthase
C1N55_RS15140	COG0069	glutamate synthase activity
C1N55_RS15140	COG0067	glutamate synthase
C1N55_RS15140	COG0070	glutamate synthase
C1N55_RS15145	COG0583	DNA-binding transcription factor activity
C1N55_RS15150	COG1464	Belongs to the NlpA lipoprotein family
C1N55_RS15155	COG2011	ABC-type metal ion transport system permease component
C1N55_RS15160	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C1N55_RS15165	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C1N55_RS15170	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
C1N55_RS15180	COG1393	Belongs to the ArsC family
C1N55_RS15185	COG1960	acyl-CoA dehydrogenase activity
C1N55_RS15190	COG0183	Belongs to the thiolase family
C1N55_RS15195	COG1024	Enoyl-CoA hydratase
C1N55_RS15195	COG1250	3-hydroxyacyl-CoA dehydrogenase
C1N55_RS15200	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C1N55_RS15205	COG1942	4-Oxalocrotonate Tautomerase
C1N55_RS15210	COG1011	Hydrolase
C1N55_RS15220	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C1N55_RS15230	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
C1N55_RS15235	COG1764	response to oxidative stress
C1N55_RS15275	COG0642	Histidine kinase
C1N55_RS15280	COG0745	RESPONSE REGULATOR receiver
C1N55_RS15285	COG0596	Alpha beta hydrolase
C1N55_RS15295	COG0697	spore germination
C1N55_RS15310	COG0840	transmembrane signaling receptor activity
C1N55_RS15325	COG0697	spore germination
C1N55_RS15330	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C1N55_RS15335	COG1012	belongs to the aldehyde dehydrogenase family
C1N55_RS15355	COG0697	spore germination
C1N55_RS15380	COG2801	Transposase and inactivated derivatives
C1N55_RS15395	COG4512	PFAM Accessory gene regulator B
C1N55_RS15410	COG1309	transcriptional regulator
C1N55_RS15430	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C1N55_RS15430	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C1N55_RS15510	COG2076	Multidrug Resistance protein
C1N55_RS15515	COG2076	Multidrug Resistance protein
C1N55_RS15540	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
C1N55_RS15545	COG1024	Enoyl-CoA hydratase
C1N55_RS15560	COG2808	Putative FMN-binding domain
C1N55_RS15565	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C1N55_RS15575	COG2610	gluconate transmembrane transporter activity
C1N55_RS15580	COG1929	Belongs to the glycerate kinase type-1 family
C1N55_RS15585	COG3835	regulator
C1N55_RS15590	COG2814	Major facilitator Superfamily
C1N55_RS15595	COG0753	catalase activity
C1N55_RS15600	COG1028	Short-chain dehydrogenase reductase Sdr
C1N55_RS15610	COG2851	Citrate transporter
C1N55_RS15615	COG4565	transcriptional regulatory protein
C1N55_RS15620	COG3290	protein histidine kinase activity
C1N55_RS15625	COG0656	L-ascorbic acid biosynthetic process
C1N55_RS15630	COG2267	carboxylic ester hydrolase activity
C1N55_RS15650	COG0657	acetylesterase activity
C1N55_RS15655	COG2072	flavoprotein involved in K transport
C1N55_RS15660	COG2197	response regulator
C1N55_RS15665	COG1126	abc transporter atp-binding protein
C1N55_RS15670	COG0765	amino acid transport
C1N55_RS15675	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C1N55_RS15680	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C1N55_RS15685	COG0800	Aldolase
C1N55_RS15695	COG1028	Short-chain dehydrogenase reductase Sdr
C1N55_RS15700	COG1028	Short-chain dehydrogenase reductase Sdr
C1N55_RS15705	COG1063	alcohol dehydrogenase
C1N55_RS15715	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
C1N55_RS15725	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C1N55_RS15745	COG1120	ATPase activity
C1N55_RS15750	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C1N55_RS15755	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C1N55_RS15760	COG4607	ABC-type enterochelin transport system periplasmic component
C1N55_RS15780	COG1473	amidohydrolase
C1N55_RS15795	COG3835	regulator
C1N55_RS15805	COG1012	belongs to the aldehyde dehydrogenase family
C1N55_RS15810	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C1N55_RS15815	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C1N55_RS15825	COG1012	belongs to the aldehyde dehydrogenase family
C1N55_RS15830	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C1N55_RS15860	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
C1N55_RS15875	COG1012	belongs to the aldehyde dehydrogenase family
C1N55_RS15885	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
C1N55_RS15895	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
C1N55_RS15895	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
C1N55_RS15915	COG3279	Response regulator of the LytR AlgR family
C1N55_RS15925	COG4608	Belongs to the ABC transporter superfamily
C1N55_RS15930	COG0444	Belongs to the ABC transporter superfamily
C1N55_RS15935	COG0601	transmembrane transport
C1N55_RS15950	COG0402	S-adenosylhomocysteine deaminase activity
C1N55_RS15955	COG0402	S-adenosylhomocysteine deaminase activity
C1N55_RS16115	COG0557	exoribonuclease II activity
C1N55_RS16120	COG1647	Serine aminopeptidase, S33
C1N55_RS16125	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C1N55_RS16130	COG0385	Bile acid
C1N55_RS16135	COG1785	Belongs to the alkaline phosphatase family
C1N55_RS16140	COG1120	ATPase activity
C1N55_RS16145	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C1N55_RS16165	COG0697	spore germination
C1N55_RS16170	COG1280	lysine exporter protein (LysE YggA)
C1N55_RS16180	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
C1N55_RS16190	COG0126	phosphoglycerate kinase activity
C1N55_RS16200	COG2390	Transcriptional regulator
C1N55_RS16210	COG5577	PFAM Coat F domain
C1N55_RS16230	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C1N55_RS16240	COG0391	Required for morphogenesis under gluconeogenic growth conditions
C1N55_RS16250	COG1051	belongs to the nudix hydrolase family
C1N55_RS16255	COG0492	ferredoxin-NADP+ reductase activity
C1N55_RS16260	COG0457	Tetratricopeptide repeat
C1N55_RS16265	COG0140	phosphoribosyl-ATP diphosphatase activity
C1N55_RS16265	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
C1N55_RS16275	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
C1N55_RS16280	COG0131	Imidazoleglycerol-phosphate dehydratase
C1N55_RS16285	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
C1N55_RS16305	COG0110	maltose O-acetyltransferase activity
C1N55_RS16310	COG0546	phosphoglycolate phosphatase activity
C1N55_RS16320	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
C1N55_RS16325	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C1N55_RS16330	COG1024	Enoyl-CoA hydratase
C1N55_RS16335	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C1N55_RS16340	COG0511	ligase activity, forming carbon-carbon bonds
C1N55_RS16345	COG0439	Biotin carboxylase
C1N55_RS16350	COG0318	PFAM AMP-dependent synthetase and ligase
C1N55_RS16355	COG1960	acyl-CoA dehydrogenase activity
C1N55_RS16365	COG2010	Cytochrome c
C1N55_RS16370	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C1N55_RS16375	COG1854	S-ribosylhomocysteine lyase activity
C1N55_RS16380	COG4946	Tricorn protease homolog
C1N55_RS16380	COG1506	peptidase
C1N55_RS16380	COG0823	Involved in the tonB-independent uptake of proteins
C1N55_RS16385	COG0318	PFAM AMP-dependent synthetase and ligase
C1N55_RS16390	COG0577	efflux transmembrane transporter activity
C1N55_RS16395	COG1136	(ABC) transporter
C1N55_RS16400	COG2205	protein histidine kinase activity
C1N55_RS16405	COG0745	RESPONSE REGULATOR receiver
C1N55_RS16410	COG0095	Lipoate-protein ligase
C1N55_RS16420	COG1476	TRANSCRIPTIONal
C1N55_RS16435	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
C1N55_RS16440	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
C1N55_RS16445	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
C1N55_RS16450	COG2329	Antibiotic biosynthesis monooxygenase
C1N55_RS16475	COG1131	(ABC) transporter
C1N55_RS16480	COG0537	adenosine 5'-monophosphoramidase activity
C1N55_RS16515	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C1N55_RS16520	COG2824	Alkylphosphonate utilization operon protein PhnA
C1N55_RS16525	COG1999	signal sequence binding
C1N55_RS16530	COG3481	metal-dependent phosphohydrolase, HD sub domain
C1N55_RS16540	COG1024	Enoyl-CoA hydratase
C1N55_RS16545	COG3573	Dehydrogenase
C1N55_RS16550	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C1N55_RS16555	COG1011	Hydrolase
C1N55_RS16575	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C1N55_RS16600	COG1132	(ABC) transporter
C1N55_RS16605	COG1132	(ABC) transporter
C1N55_RS16610	COG1253	flavin adenine dinucleotide binding
C1N55_RS16615	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
C1N55_RS16620	COG2197	response regulator
C1N55_RS16625	COG4585	Histidine kinase
C1N55_RS16625	COG2203	Gaf domain
C1N55_RS16630	COG1802	Transcriptional regulator
C1N55_RS16635	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
C1N55_RS16640	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C1N55_RS16645	COG0564	pseudouridine synthase activity
C1N55_RS16650	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C1N55_RS16655	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
C1N55_RS16675	COG0656	L-ascorbic acid biosynthetic process
C1N55_RS16680	COG0318	PFAM AMP-dependent synthetase and ligase
C1N55_RS16690	COG2514	catechol 2,3-dioxygenase activity
C1N55_RS16695	COG0346	lactoylglutathione lyase activity
C1N55_RS16700	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
C1N55_RS16720	COG1619	proteins homologs of microcin C7 resistance protein MccF
C1N55_RS16725	COG0784	Response regulator, receiver
C1N55_RS16725	COG5002	protein histidine kinase activity
C1N55_RS16730	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
C1N55_RS16735	COG2208	phosphoserine phosphatase activity
C1N55_RS16740	COG3706	GGDEF domain
C1N55_RS16745	COG0840	transmembrane signaling receptor activity
C1N55_RS16755	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C1N55_RS16760	COG3344	reverse transcriptase
C1N55_RS16785	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C1N55_RS16790	COG1309	transcriptional regulator
C1N55_RS16795	COG1131	(ABC) transporter
C1N55_RS16875	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C1N55_RS16890	COG3344	reverse transcriptase
C1N55_RS16915	COG0582	viral genome integration into host DNA
C1N55_RS17035	COG0735	belongs to the Fur family
C1N55_RS17045	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C1N55_RS17055	COG4129	membrane
C1N55_RS17070	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C1N55_RS17080	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C1N55_RS17085	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C1N55_RS17090	COG0601	transmembrane transport
C1N55_RS17095	COG0747	negative chemotaxis
C1N55_RS17100	COG4608	Belongs to the ABC transporter superfamily
C1N55_RS17105	COG0444	Belongs to the ABC transporter superfamily
C1N55_RS17110	COG1132	(ABC) transporter
C1N55_RS17115	COG3557	Belongs to the UPF0374 family
C1N55_RS17125	COG1988	membrane-bound metal-dependent
C1N55_RS17140	COG2137	regulation of response to DNA damage stimulus
C1N55_RS17160	COG0307	riboflavin synthase, alpha
C1N55_RS17165	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C1N55_RS17170	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
C1N55_RS17175	COG1131	(ABC) transporter
C1N55_RS17190	COG1725	Transcriptional regulator
C1N55_RS17205	COG0477	Major facilitator Superfamily
C1N55_RS17225	COG2217	Heavy metal translocating P-type atpase
C1N55_RS17230	COG1295	ribonuclease BN
C1N55_RS17240	COG4840	Belongs to the UPF0435 family
C1N55_RS17250	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C1N55_RS17255	COG1360	Flagellar Motor Protein
C1N55_RS17260	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C1N55_RS17265	COG0288	reversible hydration of carbon dioxide
C1N55_RS17270	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C1N55_RS17285	COG0024	Methionine aminopeptidase
C1N55_RS17290	COG3859	Proton-coupled thiamine transporter YuaJ
C1N55_RS17300	COG0419	ATPase involved in DNA repair
C1N55_RS17305	COG0420	3'-5' exonuclease activity
C1N55_RS17310	COG2309	aminopeptidase activity
C1N55_RS17315	COG0513	Belongs to the DEAD box helicase family
C1N55_RS17320	COG1794	racemase activity, acting on amino acids and derivatives
C1N55_RS17330	COG0183	Belongs to the thiolase family
C1N55_RS17335	COG0318	PFAM AMP-dependent synthetase and ligase
C1N55_RS17340	COG1960	acyl-CoA dehydrogenase activity
C1N55_RS17360	COG0435	Glutathione S-transferase
C1N55_RS17380	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C1N55_RS17385	COG0697	spore germination
C1N55_RS17390	COG1376	ErfK ybiS ycfS ynhG family protein
C1N55_RS17395	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C1N55_RS17410	COG0753	catalase activity
C1N55_RS17415	COG2719	SpoVR family
C1N55_RS17420	COG2718	Belongs to the UPF0229 family
C1N55_RS17425	COG2766	serine protein kinase
C1N55_RS17440	COG3546	catalase activity
C1N55_RS17445	COG0697	spore germination
C1N55_RS17475	COG5001	Diguanylate cyclase
C1N55_RS17475	COG1716	ATPase activity
C1N55_RS17480	COG2404	hydrolase activity, acting on ester bonds
C1N55_RS17495	COG0737	Belongs to the 5'-nucleotidase family
C1N55_RS17505	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C1N55_RS17510	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C1N55_RS17515	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C1N55_RS17530	COG0473	3-isopropylmalate dehydrogenase activity
C1N55_RS17550	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
C1N55_RS17555	COG2309	aminopeptidase activity
C1N55_RS17560	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
C1N55_RS17565	COG4807	Protein conserved in bacteria
C1N55_RS17570	COG1522	sequence-specific DNA binding
C1N55_RS17575	COG0436	Aminotransferase
C1N55_RS17580	COG1115	amino acid carrier protein
C1N55_RS17590	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C1N55_RS17595	COG1321	iron dependent repressor
C1N55_RS17595	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C1N55_RS17600	COG1121	(ABC) transporter
C1N55_RS17605	COG0803	Belongs to the bacterial solute-binding protein 9 family
C1N55_RS17610	COG0840	transmembrane signaling receptor activity
C1N55_RS17610	COG3290	protein histidine kinase activity
C1N55_RS17620	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
C1N55_RS17620	COG0392	lysyltransferase activity
C1N55_RS17625	COG0840	transmembrane signaling receptor activity
C1N55_RS17630	COG0840	transmembrane signaling receptor activity
C1N55_RS17630	COG5278	phosphoserine phosphatase activity
C1N55_RS17645	COG1368	sulfuric ester hydrolase activity
C1N55_RS17650	COG3584	3D domain protein
C1N55_RS17650	COG1388	LysM domain
C1N55_RS17655	COG3973	AAA domain
C1N55_RS17660	COG0791	NLP P60 protein
C1N55_RS17690	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C1N55_RS17700	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C1N55_RS17705	COG2814	Major facilitator Superfamily
C1N55_RS17715	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C1N55_RS17720	COG1597	lipid kinase activity
C1N55_RS17745	COG4851	CamS sex pheromone cAM373 precursor
C1N55_RS17755	COG0210	DNA helicase
C1N55_RS17765	COG4496	protein, YerC YecD
C1N55_RS17770	COG1470	cell adhesion involved in biofilm formation
C1N55_RS17775	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
C1N55_RS17785	COG0151	Belongs to the GarS family
C1N55_RS17795	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C1N55_RS17805	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
C1N55_RS17820	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C1N55_RS17830	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C1N55_RS17835	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C1N55_RS17840	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
C1N55_RS17850	COG0745	RESPONSE REGULATOR receiver
C1N55_RS17855	COG3850	Histidine kinase
C1N55_RS17855	COG5002	protein histidine kinase activity
C1N55_RS17880	COG0668	transmembrane transport
C1N55_RS17930	COG1051	belongs to the nudix hydrolase family
C1N55_RS17955	COG2252	PERMEase
C1N55_RS17970	COG3689	TIGRFAM TIGR03943 family protein
C1N55_RS17975	COG0701	Predicted permease
C1N55_RS17980	COG1696	Membrane protein involved in D-alanine export
C1N55_RS17990	COG0519	Catalyzes the synthesis of GMP from XMP
C1N55_RS17990	COG0518	GMP synthase (glutamine-hydrolyzing) activity
C1N55_RS17995	COG1305	Transglutaminase-like
C1N55_RS18000	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
C1N55_RS18005	COG0714	Associated with various cellular activities
C1N55_RS18020	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
C1N55_RS18025	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C1N55_RS18030	COG0390	transport system, permease component
C1N55_RS18035	COG0506	proline dehydrogenase activity
C1N55_RS18040	COG2197	response regulator
C1N55_RS18045	COG4585	Histidine kinase
C1N55_RS18050	COG3239	Fatty acid desaturase
C1N55_RS18055	COG0646	methionine synthase
C1N55_RS18055	COG1410	methionine synthase
C1N55_RS18060	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
C1N55_RS18060	COG0646	methionine synthase
C1N55_RS18065	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
C1N55_RS18075	COG0583	DNA-binding transcription factor activity
C1N55_RS18080	COG1647	Serine aminopeptidase, S33
C1N55_RS18085	COG1379	DNA repair
C1N55_RS18090	COG0840	transmembrane signaling receptor activity
C1N55_RS18100	COG2363	Small membrane protein
C1N55_RS18115	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
C1N55_RS18120	COG3285	dna ligase
C1N55_RS18120	COG1793	dna ligase
C1N55_RS18140	COG0640	Transcriptional regulator
C1N55_RS18150	COG1388	LysM domain
C1N55_RS18150	COG3858	chitin binding
C1N55_RS18155	COG2200	EAL domain
C1N55_RS18160	COG2814	Major facilitator Superfamily
C1N55_RS18165	COG1309	transcriptional regulator
C1N55_RS18180	COG0840	transmembrane signaling receptor activity
C1N55_RS18180	COG3290	protein histidine kinase activity
C1N55_RS18200	COG0477	Major facilitator Superfamily
C1N55_RS18205	COG1309	transcriptional regulator
C1N55_RS18210	COG3403	YqcI/YcgG family
C1N55_RS18215	COG0577	efflux transmembrane transporter activity
C1N55_RS18215	COG1136	(ABC) transporter
C1N55_RS18225	COG1442	glycosyl transferase family 8
C1N55_RS18225	COG1216	Glycosyl transferase, family 2
C1N55_RS18230	COG1442	glycosyl transferase family 8
C1N55_RS18230	COG1216	Glycosyl transferase, family 2
C1N55_RS18235	COG1216	Glycosyl transferase, family 2
C1N55_RS18235	COG0463	Glycosyl transferase, family 2
C1N55_RS18255	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
C1N55_RS18260	COG1266	CAAX protease self-immunity
C1N55_RS18265	COG0805	protein transport
C1N55_RS18270	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C1N55_RS18280	COG0488	(ABC) transporter
C1N55_RS18290	COG0456	acetyltransferase
C1N55_RS18295	COG1214	PFAM Peptidase M22, glycoprotease
C1N55_RS18300	COG0802	atpase or kinase
C1N55_RS18375	COG2183	response to ionizing radiation
C1N55_RS18380	COG1191	sigma factor activity
C1N55_RS18385	COG2172	sigma factor antagonist activity
C1N55_RS18390	COG1366	Belongs to the anti-sigma-factor antagonist family
C1N55_RS18395	COG2208	phosphoserine phosphatase activity
C1N55_RS18400	COG2172	sigma factor antagonist activity
C1N55_RS18405	COG2337	Toxic component of a toxin-antitoxin (TA) module
C1N55_RS18420	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
C1N55_RS18425	COG0736	holo-[acyl-carrier-protein] synthase activity
C1N55_RS18430	COG0705	Rhomboid family
C1N55_RS18435	COG3428	Bacterial PH domain
C1N55_RS18440	COG3402	PFAM membrane-flanked domain
C1N55_RS18445	COG0513	Belongs to the DEAD box helicase family
C1N55_RS18450	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C1N55_RS18455	COG1181	Belongs to the D-alanine--D-alanine ligase family
C1N55_RS18465	COG0772	Belongs to the SEDS family
C1N55_RS18475	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C1N55_RS18480	COG1876	peptidase activity
C1N55_RS18485	COG3344	reverse transcriptase
C1N55_RS18490	COG0706	membrane insertase activity
C1N55_RS18500	COG3279	Response regulator of the LytR AlgR family
C1N55_RS18505	COG0427	acetyl-CoA hydrolase
C1N55_RS18510	COG1368	sulfuric ester hydrolase activity
C1N55_RS18530	COG2996	Protein conserved in bacteria
C1N55_RS18545	COG0708	Exodeoxyribonuclease III
C1N55_RS18550	COG0812	UDP-N-acetylmuramate dehydrogenase activity
C1N55_RS18555	COG1733	regulation of RNA biosynthetic process
C1N55_RS18570	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
C1N55_RS18575	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C1N55_RS18575	COG0723	plastoquinol--plastocyanin reductase activity
C1N55_RS18580	COG1227	inorganic diphosphatase activity
C1N55_RS18590	COG0477	Major facilitator Superfamily
C1N55_RS18595	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C1N55_RS18605	COG2910	NAD(P)H-binding
C1N55_RS18615	COG0671	phosphoesterase, PA-phosphatase related
C1N55_RS18620	COG2329	Antibiotic biosynthesis monooxygenase
C1N55_RS18625	COG4607	ABC-type enterochelin transport system periplasmic component
C1N55_RS18630	COG4604	ABC transporter, ATP-binding protein
C1N55_RS18635	COG4605	iron ion homeostasis
C1N55_RS18640	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C1N55_RS18650	COG3104	oligopeptide transport
C1N55_RS18655	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C1N55_RS18660	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C1N55_RS18670	COG1392	Phosphate transport regulator
C1N55_RS18675	COG0306	phosphate transporter
C1N55_RS18690	COG0628	permease
C1N55_RS18700	COG0217	transcriptional regulatory protein
C1N55_RS18705	COG2321	neutral zinc metallopeptidase
C1N55_RS18710	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C1N55_RS18720	COG0204	Acyl-transferase
C1N55_RS18725	COG0500	methyltransferase
C1N55_RS18730	COG2271	Major facilitator Superfamily
C1N55_RS18740	COG2207	Transcriptional regulator
C1N55_RS18740	COG3708	Transcriptional regulator
C1N55_RS18745	COG3279	Response regulator of the LytR AlgR family
C1N55_RS18780	COG4175	Glycine betaine
C1N55_RS18780	COG3448	diguanylate cyclase activity
C1N55_RS18790	COG0789	Transcriptional regulator
C1N55_RS18800	COG3424	synthase
C1N55_RS18805	COG1755	Isoprenylcysteine carboxyl methyltransferase
C1N55_RS18815	COG1252	NADH dehydrogenase
C1N55_RS18825	COG2223	nitrite transmembrane transporter activity
C1N55_RS18830	COG0586	Pfam SNARE associated Golgi protein
C1N55_RS18840	COG4608	Belongs to the ABC transporter superfamily
C1N55_RS18845	COG0444	Belongs to the ABC transporter superfamily
C1N55_RS18850	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C1N55_RS18855	COG0601	transmembrane transport
C1N55_RS18860	COG4166	transmembrane transport
C1N55_RS18865	COG4608	Belongs to the ABC transporter superfamily
C1N55_RS18870	COG0444	Belongs to the ABC transporter superfamily
C1N55_RS18875	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C1N55_RS18880	COG0601	transmembrane transport
C1N55_RS18885	COG4166	transmembrane transport
C1N55_RS18910	COG5566	PFAM Mor transcription activator
C1N55_RS18920	COG2200	EAL domain
C1N55_RS18920	COG2199	diguanylate cyclase activity
C1N55_RS18920	COG3287	FIST C domain
C1N55_RS18930	COG0488	(ABC) transporter
C1N55_RS18950	COG2318	DinB family
C1N55_RS18965	COG2124	cytochrome p450
C1N55_RS18985	COG3377	Domain of unknown function (DUF1805)
C1N55_RS19010	COG0598	Magnesium transport protein CorA
C1N55_RS19015	COG1174	glycine betaine transport
C1N55_RS19035	COG5504	Zn-dependent protease
C1N55_RS19045	COG0640	Transcriptional regulator
C1N55_RS19050	COG3832	glyoxalase III activity
C1N55_RS19060	COG3119	arylsulfatase activity
C1N55_RS19065	COG2318	DinB family
C1N55_RS19070	COG2211	Major facilitator Superfamily
C1N55_RS19075	COG0840	transmembrane signaling receptor activity
C1N55_RS19080	COG0385	Bile acid
C1N55_RS19090	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C1N55_RS19095	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C1N55_RS19100	COG1780	Probably involved in ribonucleotide reductase function
C1N55_RS19105	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C1N55_RS19120	COG1279	arginine transmembrane transporter activity
C1N55_RS19125	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C1N55_RS19130	COG2197	response regulator
C1N55_RS19135	COG1250	3-hydroxyacyl-CoA dehydrogenase
C1N55_RS19135	COG1024	Enoyl-CoA hydratase
C1N55_RS19160	COG2267	carboxylic ester hydrolase activity
C1N55_RS19165	COG3340	Belongs to the peptidase S51 family
C1N55_RS19185	COG4585	Histidine kinase
C1N55_RS19190	COG2197	response regulator
C1N55_RS19195	COG1607	acyl-coa hydrolase
C1N55_RS19205	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C1N55_RS19215	COG2814	Major facilitator Superfamily
C1N55_RS19220	COG5646	InterPro IPR014922
C1N55_RS19225	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
C1N55_RS19230	COG1971	Probably functions as a manganese efflux pump
C1N55_RS19240	COG0346	lactoylglutathione lyase activity
C1N55_RS19245	COG0640	Transcriptional regulator
C1N55_RS19250	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C1N55_RS19255	COG0693	protein deglycase activity
C1N55_RS19265	COG4856	YbbR-like protein
C1N55_RS19270	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
C1N55_RS19275	COG5662	AntiSigma factor
C1N55_RS19280	COG1595	DNA-templated transcription, initiation
C1N55_RS19335	COG2194	sulfuric ester hydrolase activity
C1N55_RS19345	COG0489	protein tyrosine kinase activity
C1N55_RS19350	COG0584	glycerophosphoryl diester phosphodiesterase
C1N55_RS19360	COG0395	ABC-type sugar transport system, permease component
C1N55_RS19370	COG3842	ATPase activity
C1N55_RS19375	COG0860	N-Acetylmuramoyl-L-alanine amidase
C1N55_RS19380	COG1132	(ABC) transporter
C1N55_RS19385	COG1132	(ABC) transporter
C1N55_RS19395	COG3153	acetyltransferase
C1N55_RS19395	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C1N55_RS19400	COG0456	acetyltransferase
C1N55_RS19405	COG2323	membrane
C1N55_RS19420	COG1028	Short-chain dehydrogenase reductase Sdr
C1N55_RS19430	COG0351	phosphomethylpyrimidine kinase
C1N55_RS19445	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
C1N55_RS19455	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
C1N55_RS19460	COG1122	ATPase activity
C1N55_RS19465	COG1122	ATPase activity
C1N55_RS19475	COG0202	RNA polymerase activity
C1N55_RS19490	COG0257	Belongs to the bacterial ribosomal protein bL36 family
C1N55_RS19495	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
C1N55_RS19505	COG0201	protein transport
C1N55_RS19540	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
C1N55_RS19590	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
C1N55_RS19610	COG0051	transcription antitermination factor activity, RNA binding
C1N55_RS19615	COG0577	efflux transmembrane transporter activity
C1N55_RS19620	COG1136	(ABC) transporter
C1N55_RS19625	COG0642	Histidine kinase
C1N55_RS19630	COG0745	RESPONSE REGULATOR receiver
C1N55_RS19645	COG0049	tRNA binding
C1N55_RS19655	COG1358	cellular component organization or biogenesis
C1N55_RS19670	COG2813	Specifically methylates the guanine in position
C1N55_RS19695	COG0250	Participates in transcription elongation, termination and antitermination
C1N55_RS19700	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C1N55_RS19715	COG3688	RNA-binding protein containing a PIN domain
C1N55_RS19720	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C1N55_RS19750	COG4956	integral membrane protein (PIN domain superfamily)
C1N55_RS19755	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
C1N55_RS19760	COG0542	response to heat
C1N55_RS19765	COG3869	Catalyzes the specific phosphorylation of arginine residues in
C1N55_RS19790	COG0840	transmembrane signaling receptor activity
C1N55_RS19795	COG1607	acyl-coa hydrolase
C1N55_RS19800	COG1012	belongs to the aldehyde dehydrogenase family
C1N55_RS19815	COG1012	belongs to the aldehyde dehydrogenase family
C1N55_RS19820	COG1187	pseudouridine synthase activity
C1N55_RS19860	COG2205	protein histidine kinase activity
C1N55_RS19875	COG1473	amidohydrolase
C1N55_RS19885	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C1N55_RS19890	COG0805	protein transport
C1N55_RS19895	COG0531	amino acid
C1N55_RS19900	COG1309	transcriptional regulator
C1N55_RS19905	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C1N55_RS19915	COG3858	chitin binding
C1N55_RS19915	COG1388	LysM domain
C1N55_RS19920	COG5001	Diguanylate cyclase
C1N55_RS19920	COG3447	MASE1 domain protein
C1N55_RS19920	COG5002	protein histidine kinase activity
C1N55_RS19945	COG3541	Predicted nucleotidyltransferase
C1N55_RS19950	COG0346	lactoylglutathione lyase activity
C1N55_RS19965	COG1404	Belongs to the peptidase S8 family
C1N55_RS19965	COG4412	M6 family metalloprotease domain protein
C1N55_RS19975	COG0456	acetyltransferase
C1N55_RS20005	COG3274	enterobacterial common antigen metabolic process
C1N55_RS20015	COG0494	nUDIX hydrolase
C1N55_RS20020	COG2610	gluconate transmembrane transporter activity
C1N55_RS20025	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
C1N55_RS20035	COG0018	arginyl-trna synthetase
C1N55_RS20075	COG0840	transmembrane signaling receptor activity
C1N55_RS20095	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C1N55_RS20105	COG1533	DNA photolyase activity
C1N55_RS20110	COG0450	alkyl hydroperoxide reductase
C1N55_RS20115	COG3634	alkyl hydroperoxide reductase activity
C1N55_RS20125	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C1N55_RS20125	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
C1N55_RS20150	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C1N55_RS20160	COG0753	catalase activity
C1N55_RS20170	COG0412	Dienelactone hydrolase
C1N55_RS20180	COG3708	Transcriptional regulator
C1N55_RS20180	COG2207	Transcriptional regulator
C1N55_RS20190	COG1611	Belongs to the LOG family
C1N55_RS20195	COG1694	Mazg nucleotide pyrophosphohydrolase
C1N55_RS20210	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C1N55_RS20215	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
C1N55_RS20220	COG4853	Protein conserved in bacteria
C1N55_RS20225	COG4863	YycH protein
C1N55_RS20230	COG5002	protein histidine kinase activity
C1N55_RS20235	COG0745	RESPONSE REGULATOR receiver
C1N55_RS20240	COG0739	heme binding
C1N55_RS20240	COG0741	lytic transglycosylase activity
C1N55_RS20240	COG1196	nuclear chromosome segregation
C1N55_RS20245	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C1N55_RS20255	COG0305	Participates in initiation and elongation during chromosome replication
C1N55_RS20265	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
C1N55_RS20275	COG4536	flavin adenine dinucleotide binding
C1N55_RS20280	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
C1N55_RS20285	COG0629	single-stranded DNA binding
C1N55_RS20290	COG0360	Binds together with S18 to 16S ribosomal RNA
C1N55_RS20305	COG0012	GTP binding
C1N55_RS20310	COG4481	Protein conserved in bacteria
C1N55_RS20315	COG0668	transmembrane transport
C1N55_RS20325	COG1811	Na channel or pump
C1N55_RS20330	COG1475	DNA binding
C1N55_RS20335	COG1192	Involved in chromosome partitioning
C1N55_RS20360	COG1847	R3H domain protein
C1N55_RS20370	COG0594	ribonuclease P activity