locus-tag	class	description
CNO08_RS00010	COG0592	DNA-directed DNA polymerase activity
CNO08_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CNO08_RS00020	COG0187	DNA topoisomerase II activity
CNO08_RS00065	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CNO08_RS00075	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CNO08_RS00100	COG0583	DNA-binding transcription factor activity
CNO08_RS00105	COG4977	sequence-specific DNA binding
CNO08_RS00130	COG0490	domain, Protein
CNO08_RS00130	COG0471	metal ion transport
CNO08_RS00140	COG0784	Response regulator, receiver
CNO08_RS00195	COG2204	response regulator
CNO08_RS00230	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CNO08_RS00265	COG1595	DNA-templated transcription, initiation
CNO08_RS00275	COG2197	response regulator
CNO08_RS00280	COG4585	Histidine kinase
CNO08_RS00310	COG3186	Phenylalanine-4-hydroxylase
CNO08_RS00315	COG1522	sequence-specific DNA binding
CNO08_RS00325	COG1794	racemase activity, acting on amino acids and derivatives
CNO08_RS00335	COG2194	sulfuric ester hydrolase activity
CNO08_RS00340	COG2815	serine threonine protein kinase
CNO08_RS00340	COG0515	serine threonine protein kinase
CNO08_RS00375	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CNO08_RS00425	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CNO08_RS00430	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CNO08_RS00435	COG1127	ABC transporter
CNO08_RS00440	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CNO08_RS00445	COG1074	ATP-dependent DNA helicase activity
CNO08_RS00490	COG3300	MHYT domain
CNO08_RS00490	COG5001	Diguanylate cyclase
CNO08_RS00500	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CNO08_RS00505	COG1136	(ABC) transporter
CNO08_RS00505	COG0577	efflux transmembrane transporter activity
CNO08_RS00525	COG1136	(ABC) transporter
CNO08_RS00540	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
CNO08_RS00545	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
CNO08_RS00575	COG0753	catalase activity
CNO08_RS00630	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CNO08_RS00635	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CNO08_RS00640	COG2188	Transcriptional regulator
CNO08_RS00645	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CNO08_RS00650	COG0363	glucosamine-6-phosphate deaminase activity
CNO08_RS00655	COG0129	dihydroxy-acid dehydratase activity
CNO08_RS00660	COG0546	phosphoglycolate phosphatase activity
CNO08_RS00665	COG0800	Aldolase
CNO08_RS00670	COG1609	Transcriptional regulator
CNO08_RS00675	COG2050	protein possibly involved in aromatic compounds catabolism
CNO08_RS00685	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CNO08_RS00715	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CNO08_RS00735	COG0405	Gamma-glutamyltransferase
CNO08_RS00760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CNO08_RS00760	COG2205	protein histidine kinase activity
CNO08_RS00775	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CNO08_RS00815	COG1881	PFAM PEBP family protein
CNO08_RS00820	COG1028	Short-chain dehydrogenase reductase Sdr
CNO08_RS00845	COG1968	undecaprenyl-diphosphatase activity
CNO08_RS00850	COG0174	glutamine synthetase
CNO08_RS00855	COG0454	-acetyltransferase
CNO08_RS00870	COG0004	ammonium transporteR
CNO08_RS00875	COG3128	pkhd-type hydroxylase
CNO08_RS00880	COG1404	Belongs to the peptidase S8 family
CNO08_RS00890	COG1609	Transcriptional regulator
CNO08_RS00895	COG1472	Belongs to the glycosyl hydrolase 3 family
CNO08_RS00900	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
CNO08_RS00905	COG2847	Copper chaperone PCu(A)C
CNO08_RS00910	COG1999	signal sequence binding
CNO08_RS00935	COG1987	bacterial-type flagellum assembly
CNO08_RS00950	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CNO08_RS00955	COG4566	intracellular signal transduction
CNO08_RS00960	COG4191	Histidine kinase
CNO08_RS00970	COG4789	Type iii secretion
CNO08_RS00990	COG4669	(LipO)protein
CNO08_RS01050	COG0438	transferase activity, transferring glycosyl groups
CNO08_RS01065	COG4206	TonB-dependent receptor
CNO08_RS01075	COG2764	glyoxalase bleomycin resistance protein dioxygenase
CNO08_RS01080	COG4941	Belongs to the sigma-70 factor family
CNO08_RS01090	COG1116	anion transmembrane transporter activity
CNO08_RS01130	COG2132	Multicopper oxidase
CNO08_RS01155	COG0861	Integral membrane protein TerC family
CNO08_RS01175	COG2249	NAD(P)H dehydrogenase (quinone) activity
CNO08_RS01185	COG1446	asparaginase
CNO08_RS01215	COG4106	trans-aconitate 2-methyltransferase activity
CNO08_RS01255	COG3852	Histidine kinase
CNO08_RS01260	COG2204	response regulator
CNO08_RS01265	COG2032	superoxide dismutase activity
CNO08_RS01330	COG1587	Uroporphyrinogen-III synthase
CNO08_RS01345	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CNO08_RS01350	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CNO08_RS01355	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CNO08_RS01375	COG4774	siderophore transport
CNO08_RS01380	COG1131	(ABC) transporter
CNO08_RS01405	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CNO08_RS01420	COG0477	Major facilitator Superfamily
CNO08_RS01425	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CNO08_RS01430	COG0612	Peptidase, M16
CNO08_RS01445	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CNO08_RS01460	COG1842	Phage shock protein A
CNO08_RS01485	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CNO08_RS01495	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CNO08_RS01500	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CNO08_RS01515	COG0583	DNA-binding transcription factor activity
CNO08_RS01520	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CNO08_RS01525	COG2301	Belongs to the HpcH HpaI aldolase family
CNO08_RS01530	COG0596	Alpha beta hydrolase
CNO08_RS01535	COG0318	PFAM AMP-dependent synthetase and ligase
CNO08_RS01540	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CNO08_RS01560	COG0612	Peptidase, M16
CNO08_RS01565	COG0564	pseudouridine synthase activity
CNO08_RS01595	COG1802	Transcriptional regulator
CNO08_RS01600	COG3291	Pkd domain containing protein
CNO08_RS01605	COG0583	DNA-binding transcription factor activity
CNO08_RS01610	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CNO08_RS01615	COG2224	Isocitrate lyase
CNO08_RS01675	COG0277	FAD linked oxidase domain protein
CNO08_RS01680	COG0606	chelatase, subunit chli
CNO08_RS01695	COG0583	DNA-binding transcription factor activity
CNO08_RS01700	COG2855	membrane
CNO08_RS01705	COG3291	Pkd domain containing protein
CNO08_RS01715	COG1166	arginine decarboxylase activity
CNO08_RS01725	COG2084	Dehydrogenase
CNO08_RS01745	COG0018	arginyl-trna synthetase
CNO08_RS01750	COG2003	Belongs to the UPF0758 family
CNO08_RS01770	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CNO08_RS01790	COG0708	Exodeoxyribonuclease III
CNO08_RS01795	COG2807	transmembrane transport
CNO08_RS01810	COG0739	heme binding
CNO08_RS01860	COG0745	RESPONSE REGULATOR receiver
CNO08_RS01880	COG2234	aminopeptidase activity
CNO08_RS01890	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CNO08_RS01895	COG4942	peptidase
CNO08_RS01900	COG0793	Belongs to the peptidase S41A family
CNO08_RS01925	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CNO08_RS01930	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CNO08_RS01935	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CNO08_RS01960	COG2258	MOSC domain
CNO08_RS01980	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CNO08_RS01985	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CNO08_RS01990	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
CNO08_RS02015	COG1612	heme a metabolic process
CNO08_RS02020	COG0109	protoheme IX farnesyltransferase activity
CNO08_RS02025	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CNO08_RS02050	COG4946	Tricorn protease homolog
CNO08_RS02050	COG0823	Involved in the tonB-independent uptake of proteins
CNO08_RS02050	COG1506	peptidase
CNO08_RS02060	COG0358	DNA primase activity
CNO08_RS02070	COG1295	ribonuclease BN
CNO08_RS02075	COG0653	protein targeting
CNO08_RS02080	COG1610	YqeY-like protein
CNO08_RS02090	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CNO08_RS02095	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CNO08_RS02120	COG4206	TonB-dependent receptor
CNO08_RS02150	COG1090	epimerase
CNO08_RS02155	COG0741	lytic transglycosylase activity
CNO08_RS02155	COG1196	nuclear chromosome segregation
CNO08_RS02155	COG0739	heme binding
CNO08_RS02160	COG0730	response to heat
CNO08_RS02185	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CNO08_RS02200	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CNO08_RS02215	COG0366	Alpha amylase catalytic
CNO08_RS02220	COG4771	TonB-dependent receptor
CNO08_RS02250	COG4166	transmembrane transport
CNO08_RS02260	COG1335	isochorismatase
CNO08_RS02290	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CNO08_RS02300	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CNO08_RS02325	COG2207	Transcriptional regulator
CNO08_RS02375	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CNO08_RS02395	COG1397	ADP-ribosylglycohydrolase
CNO08_RS02405	COG1404	Belongs to the peptidase S8 family
CNO08_RS02410	COG1228	amidohydrolase
CNO08_RS02415	COG1307	EDD domain protein, DegV family
CNO08_RS02440	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CNO08_RS02445	COG3964	amidohydrolase
CNO08_RS02465	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CNO08_RS02470	COG0726	polysaccharide deacetylase
CNO08_RS02485	COG0436	Aminotransferase
CNO08_RS02500	COG1028	Short-chain dehydrogenase reductase Sdr
CNO08_RS02505	COG2851	Citrate transporter
CNO08_RS02520	COG0642	Histidine kinase
CNO08_RS02530	COG0281	malic enzyme
CNO08_RS02530	COG0280	phosphate acetyltransferase
CNO08_RS02545	COG0583	DNA-binding transcription factor activity
CNO08_RS02570	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CNO08_RS02585	COG1192	Involved in chromosome partitioning
CNO08_RS02600	COG2131	deaminase
CNO08_RS02645	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CNO08_RS02665	COG0642	Histidine kinase
CNO08_RS02670	COG0745	RESPONSE REGULATOR receiver
CNO08_RS02735	COG2207	Transcriptional regulator
CNO08_RS02740	COG4771	TonB-dependent receptor
CNO08_RS02760	COG3590	peptidase
CNO08_RS02805	COG3712	iron ion homeostasis
CNO08_RS02825	COG1278	Cold shock
CNO08_RS02830	COG1476	TRANSCRIPTIONal
CNO08_RS02855	COG3459	Glycosyltransferase 36 associated
CNO08_RS02930	COG3795	YCII-related domain
CNO08_RS02935	COG1720	tRNA m6t6A37 methyltransferase activity
CNO08_RS02945	COG1131	(ABC) transporter
CNO08_RS02950	COG0842	Transport permease protein
CNO08_RS02955	COG1113	amino acid transport
CNO08_RS02960	COG2304	oxidoreductase activity
CNO08_RS02980	COG2706	6-phosphogluconolactonase activity
CNO08_RS02985	COG0667	Aldo Keto reductase
CNO08_RS03010	COG4991	sh3 domain protein
CNO08_RS03060	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
CNO08_RS03060	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
CNO08_RS03080	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CNO08_RS03100	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CNO08_RS03115	COG1690	Belongs to the RtcB family
CNO08_RS03140	COG1335	isochorismatase
CNO08_RS03145	COG2329	Antibiotic biosynthesis monooxygenase
CNO08_RS03150	COG1522	sequence-specific DNA binding
CNO08_RS03225	COG4181	ATPase activity
CNO08_RS03230	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CNO08_RS03245	COG2813	Specifically methylates the guanine in position
CNO08_RS03250	COG1187	pseudouridine synthase activity
CNO08_RS03255	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CNO08_RS03265	COG1666	GTP binding
CNO08_RS03270	COG1064	alcohol dehydrogenase
CNO08_RS03285	COG0697	spore germination
CNO08_RS03305	COG0508	dehydrogenase complex catalyzes the overall conversion of
CNO08_RS03315	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CNO08_RS03340	COG0356	it plays a direct role in the translocation of protons across the membrane
CNO08_RS03350	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CNO08_RS03355	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CNO08_RS03360	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CNO08_RS03370	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CNO08_RS03375	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CNO08_RS03400	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CNO08_RS03410	COG1028	Short-chain dehydrogenase reductase Sdr
CNO08_RS03415	COG0640	Transcriptional regulator
CNO08_RS03420	COG5002	protein histidine kinase activity
CNO08_RS03440	COG0577	efflux transmembrane transporter activity
CNO08_RS03440	COG1136	(ABC) transporter
CNO08_RS03445	COG1136	(ABC) transporter
CNO08_RS03460	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CNO08_RS03545	COG4206	TonB-dependent receptor
CNO08_RS03555	COG1956	GAF domain-containing protein
CNO08_RS03560	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CNO08_RS03570	COG0720	synthase
CNO08_RS03585	COG2906	2 iron, 2 sulfur cluster binding
CNO08_RS03680	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CNO08_RS03685	COG0151	Belongs to the GarS family
CNO08_RS03695	COG0138	bifunctional purine biosynthesis protein purh
CNO08_RS03700	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CNO08_RS03705	COG2267	carboxylic ester hydrolase activity
CNO08_RS03710	COG0671	phosphoesterase, PA-phosphatase related
CNO08_RS03710	COG2453	phosphatase
CNO08_RS03735	COG4589	Belongs to the CDS family
CNO08_RS03750	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CNO08_RS03760	COG2264	protein methyltransferase activity
CNO08_RS03780	COG0439	Biotin carboxylase
CNO08_RS03790	COG0511	ligase activity, forming carbon-carbon bonds
CNO08_RS03795	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CNO08_RS03800	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CNO08_RS03830	COG0392	lysyltransferase activity
CNO08_RS03830	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CNO08_RS03835	COG0583	DNA-binding transcription factor activity
CNO08_RS03850	COG2356	endonuclease I
CNO08_RS03875	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CNO08_RS03920	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CNO08_RS03935	COG0778	Nitroreductase
CNO08_RS03940	COG2353	YceI-like domain
CNO08_RS03945	COG1741	Belongs to the pirin family
CNO08_RS03965	COG1560	Kdo2-lipid A biosynthetic process
CNO08_RS03970	COG1519	Transferase
CNO08_RS03975	COG1538	Outer membrane efflux protein
CNO08_RS03980	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CNO08_RS03985	COG1309	transcriptional regulator
CNO08_RS03990	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CNO08_RS04005	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CNO08_RS04015	COG0473	3-isopropylmalate dehydrogenase activity
CNO08_RS04020	COG0066	3-isopropylmalate dehydratase activity
CNO08_RS04040	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CNO08_RS04055	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CNO08_RS04060	COG0129	dihydroxy-acid dehydratase activity
CNO08_RS04070	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CNO08_RS04075	COG0083	homoserine kinase activity
CNO08_RS04085	COG1881	PFAM PEBP family protein
CNO08_RS04100	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CNO08_RS04110	COG3710	Transcriptional regulator
CNO08_RS04110	COG0457	Tetratricopeptide repeat
CNO08_RS04130	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CNO08_RS04170	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
CNO08_RS04200	COG0563	adenylate kinase activity
CNO08_RS04210	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CNO08_RS04220	COG0586	Pfam SNARE associated Golgi protein
CNO08_RS04230	COG1028	Short-chain dehydrogenase reductase Sdr
CNO08_RS04240	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CNO08_RS04250	COG4774	siderophore transport
CNO08_RS04255	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CNO08_RS04260	COG0352	thiamine-phosphate diphosphorylase activity
CNO08_RS04305	COG1132	(ABC) transporter
CNO08_RS04310	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CNO08_RS04325	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CNO08_RS04335	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
CNO08_RS04355	COG0006	proline dipeptidase activity
CNO08_RS04360	COG0583	DNA-binding transcription factor activity
CNO08_RS04375	COG0006	proline dipeptidase activity
CNO08_RS04390	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CNO08_RS04405	COG0346	lactoylglutathione lyase activity
CNO08_RS04410	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CNO08_RS04415	COG1561	YicC-like family, N-terminal region
CNO08_RS04430	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CNO08_RS04455	COG4771	TonB-dependent receptor
CNO08_RS04460	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CNO08_RS04480	COG0254	rRNA binding
CNO08_RS04485	COG0372	Belongs to the citrate synthase family
CNO08_RS04535	COG0714	Associated with various cellular activities
CNO08_RS04555	COG2304	oxidoreductase activity
CNO08_RS04565	COG1301	dicarboxylic acid transport
CNO08_RS04575	COG1414	Transcriptional regulator
CNO08_RS04580	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CNO08_RS04585	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CNO08_RS04595	COG3485	protocatechuate 3,4-dioxygenase
CNO08_RS04600	COG3485	protocatechuate 3,4-dioxygenase
CNO08_RS04610	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CNO08_RS04650	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CNO08_RS04655	COG4149	molybdate abc transporter
CNO08_RS04660	COG0725	ABC transporter, periplasmic molybdate-binding protein
CNO08_RS04675	COG3047	cAMP biosynthetic process
CNO08_RS04680	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CNO08_RS04715	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CNO08_RS04735	COG0126	phosphoglycerate kinase activity
CNO08_RS04760	COG0469	pyruvate kinase activity
CNO08_RS04770	COG3588	fructose-bisphosphate aldolase
CNO08_RS04795	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CNO08_RS04800	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CNO08_RS04825	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CNO08_RS04845	COG1970	mechanosensitive ion channel activity
CNO08_RS04925	COG0420	3'-5' exonuclease activity
CNO08_RS04995	COG1129	ABC transporter
CNO08_RS05000	COG0210	DNA helicase
CNO08_RS05015	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CNO08_RS05020	COG1201	RNA secondary structure unwinding
CNO08_RS05175	COG1368	sulfuric ester hydrolase activity
CNO08_RS05185	COG4067	protein conserved in archaea
CNO08_RS05185	COG0189	ligase activity
CNO08_RS05190	COG0189	ligase activity
CNO08_RS05195	COG0745	RESPONSE REGULATOR receiver
CNO08_RS05200	COG0642	Histidine kinase
CNO08_RS05205	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CNO08_RS05215	COG3291	Pkd domain containing protein
CNO08_RS05220	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CNO08_RS05230	COG0596	Alpha beta hydrolase
CNO08_RS05235	COG3275	phosphorelay sensor kinase activity
CNO08_RS05240	COG3279	Response regulator of the LytR AlgR family
CNO08_RS05275	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CNO08_RS05290	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CNO08_RS05305	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CNO08_RS05310	COG3422	double-strand break repair
CNO08_RS05335	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CNO08_RS05340	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CNO08_RS05350	COG2119	membrane
CNO08_RS05360	COG0667	Aldo Keto reductase
CNO08_RS05370	COG4771	TonB-dependent receptor
CNO08_RS05400	COG0330	HflC and HflK could
CNO08_RS05465	COG1408	metallophosphoesterase
CNO08_RS05485	COG3831	ATPase activity
CNO08_RS05490	COG0714	Associated with various cellular activities
CNO08_RS05495	COG2425	protein containing a von Willebrand factor type A (vWA) domain
CNO08_RS05500	COG3552	Protein containing von Willebrand factor type A (VWA) domain
CNO08_RS05505	COG4715	Zinc finger, swim domain protein
CNO08_RS05510	COG0655	NAD(P)H dehydrogenase (quinone) activity
CNO08_RS05520	COG2814	Major facilitator Superfamily
CNO08_RS05565	COG1960	acyl-CoA dehydrogenase activity
CNO08_RS05570	COG1309	transcriptional regulator
CNO08_RS05575	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
CNO08_RS05605	COG4206	TonB-dependent receptor
CNO08_RS05610	COG4206	TonB-dependent receptor
CNO08_RS05620	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CNO08_RS05630	COG0463	Glycosyl transferase, family 2
CNO08_RS05635	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CNO08_RS05635	COG3620	sequence-specific DNA binding
CNO08_RS05635	COG0617	tRNA 3'-terminal CCA addition
CNO08_RS05645	COG2982	Protein involved in outer membrane biogenesis
CNO08_RS05650	COG1272	protein, Hemolysin III
CNO08_RS05660	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CNO08_RS05665	COG0739	heme binding
CNO08_RS05675	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CNO08_RS05680	COG0626	cystathionine gamma-synthase activity
CNO08_RS05685	COG0460	homoserine dehydrogenase
CNO08_RS05685	COG0527	aspartate kinase activity
CNO08_RS05720	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CNO08_RS05720	COG2010	Cytochrome c
CNO08_RS05730	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CNO08_RS05730	COG2010	Cytochrome c
CNO08_RS05745	COG1760	l-serine dehydratase
CNO08_RS05760	COG3038	cytochrome b561
CNO08_RS05765	COG2353	YceI-like domain
CNO08_RS05785	COG1725	Transcriptional regulator
CNO08_RS05790	COG1131	(ABC) transporter
CNO08_RS05820	COG1335	isochorismatase
CNO08_RS05825	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CNO08_RS05830	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CNO08_RS05845	COG0259	pyridoxamine-phosphate oxidase activity
CNO08_RS05865	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CNO08_RS05870	COG5380	lipid catabolic process
CNO08_RS05890	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CNO08_RS05935	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CNO08_RS05940	COG0519	Catalyzes the synthesis of GMP from XMP
CNO08_RS05945	COG1678	Uncharacterized ACR, COG1678
CNO08_RS05950	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CNO08_RS05960	COG2824	Alkylphosphonate utilization operon protein PhnA
CNO08_RS05980	COG2239	Acts as a magnesium transporter
CNO08_RS05990	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CNO08_RS06015	COG1660	Displays ATPase and GTPase activities
CNO08_RS06025	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CNO08_RS06040	COG1137	ATPase activity
CNO08_RS06045	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CNO08_RS06055	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CNO08_RS06065	COG0271	Belongs to the BolA IbaG family
CNO08_RS06085	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CNO08_RS06090	COG4774	siderophore transport
CNO08_RS06095	COG3454	Phosphonate metabolism
CNO08_RS06100	COG2188	Transcriptional regulator
CNO08_RS06105	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CNO08_RS06135	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CNO08_RS06190	COG0628	permease
CNO08_RS06195	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CNO08_RS06200	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CNO08_RS06210	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CNO08_RS06225	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CNO08_RS06225	COG1648	precorrin-2 dehydrogenase activity
CNO08_RS06230	COG0583	DNA-binding transcription factor activity
CNO08_RS06235	COG0175	sulfate reduction
CNO08_RS06240	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CNO08_RS06245	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CNO08_RS06250	COG0175	sulfate reduction
CNO08_RS06255	COG0529	Catalyzes the synthesis of activated sulfate
CNO08_RS06255	COG2895	sulfate adenylyltransferase (ATP) activity
CNO08_RS06270	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CNO08_RS06285	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CNO08_RS06335	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CNO08_RS06340	COG1477	protein flavinylation
CNO08_RS06365	COG4774	siderophore transport
CNO08_RS06375	COG2146	nitrite reductase [NAD(P)H] activity
CNO08_RS06385	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CNO08_RS06390	COG0719	Fe-S assembly protein
CNO08_RS06395	COG0396	ATPase activity
CNO08_RS06405	COG0719	Fe-S assembly protein
CNO08_RS06420	COG1028	Short-chain dehydrogenase reductase Sdr
CNO08_RS06445	COG0697	spore germination
CNO08_RS06480	COG1280	lysine exporter protein (LysE YggA)
CNO08_RS06490	COG1196	nuclear chromosome segregation
CNO08_RS06490	COG3264	Mechanosensitive ion channel
CNO08_RS06500	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CNO08_RS06505	COG1764	response to oxidative stress
CNO08_RS06535	COG0384	phenazine biosynthesis protein PhzF
CNO08_RS06540	COG0527	aspartate kinase activity
CNO08_RS06550	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CNO08_RS06560	COG0142	geranyltranstransferase activity
CNO08_RS06680	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CNO08_RS06685	COG4786	Flagellar basal body rod
CNO08_RS06700	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CNO08_RS06705	COG1706	bacterial-type flagellum-dependent cell motility
CNO08_RS06720	COG1677	Flagellar hook-basal body complex protein FliE
CNO08_RS06725	COG1766	The M ring may be actively involved in energy transduction
CNO08_RS06740	COG1157	protein secretion by the type III secretion system
CNO08_RS06755	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CNO08_RS06760	COG1749	Flagellar hook protein flgE
CNO08_RS06800	COG0702	epimerase
CNO08_RS06805	COG0583	DNA-binding transcription factor activity
CNO08_RS06815	COG1028	Short-chain dehydrogenase reductase Sdr
CNO08_RS06835	COG1064	alcohol dehydrogenase
CNO08_RS06855	COG1733	regulation of RNA biosynthetic process
CNO08_RS06870	COG1609	Transcriptional regulator
CNO08_RS06880	COG1028	Short-chain dehydrogenase reductase Sdr
CNO08_RS06885	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
CNO08_RS06890	COG1609	Transcriptional regulator
CNO08_RS06905	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CNO08_RS06920	COG2272	Belongs to the type-B carboxylesterase lipase family
CNO08_RS06925	COG2755	lipolytic protein G-D-S-L family
CNO08_RS06955	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CNO08_RS06970	COG1028	Short-chain dehydrogenase reductase Sdr
CNO08_RS06990	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CNO08_RS06995	COG1349	DNA-binding transcription factor activity
CNO08_RS07005	COG1940	carbohydrate kinase activity
CNO08_RS07010	COG2222	sugar isomerase
CNO08_RS07040	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
CNO08_RS07075	COG3104	oligopeptide transport
CNO08_RS07080	COG1297	OPT oligopeptide transporter protein
CNO08_RS07085	COG0823	Involved in the tonB-independent uptake of proteins
CNO08_RS07085	COG1506	peptidase
CNO08_RS07100	COG2879	small protein
CNO08_RS07105	COG1966	Carbon starvation protein
CNO08_RS07110	COG0598	Magnesium transport protein CorA
CNO08_RS07120	COG4535	Mg2 and Co2 transporter CorC
CNO08_RS07170	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CNO08_RS07175	COG1702	phosphate starvation-inducible protein PhoH
CNO08_RS07195	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CNO08_RS07205	COG1309	transcriptional regulator
CNO08_RS07215	COG1131	(ABC) transporter
CNO08_RS07220	COG0842	Transport permease protein
CNO08_RS07250	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CNO08_RS07255	COG0741	lytic transglycosylase activity
CNO08_RS07260	COG0723	plastoquinol--plastocyanin reductase activity
CNO08_RS07265	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CNO08_RS07270	COG2857	Cytochrome c1
CNO08_RS07275	COG0625	glutathione transferase activity
CNO08_RS07280	COG2969	positive regulation of protein catabolic process
CNO08_RS07295	COG2835	tetraacyldisaccharide 4'-kinase activity
CNO08_RS07325	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CNO08_RS07335	COG2095	MarC family integral membrane protein
CNO08_RS07345	COG1611	Belongs to the LOG family
CNO08_RS07390	COG0556	nucleotide-excision repair
CNO08_RS07405	COG5265	(ABC) transporter
CNO08_RS07410	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CNO08_RS07415	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CNO08_RS07425	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CNO08_RS07435	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CNO08_RS07470	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CNO08_RS07515	COG1960	acyl-CoA dehydrogenase activity
CNO08_RS07525	COG2197	response regulator
CNO08_RS07530	COG4585	Histidine kinase
CNO08_RS07535	COG0515	serine threonine protein kinase
CNO08_RS07535	COG2815	serine threonine protein kinase
CNO08_RS07565	COG3153	acetyltransferase
CNO08_RS07575	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
CNO08_RS07580	COG1194	a g-specific adenine glycosylase
CNO08_RS07590	COG0552	protein localization to endoplasmic reticulum
CNO08_RS07595	COG0742	ribosomal rna small subunit methyltransferase
CNO08_RS07610	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CNO08_RS07625	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CNO08_RS07650	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CNO08_RS07660	COG4585	Histidine kinase
CNO08_RS07665	COG2197	response regulator
CNO08_RS07670	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CNO08_RS07680	COG1862	Preprotein translocase
CNO08_RS07685	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CNO08_RS07690	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CNO08_RS07715	COG5001	Diguanylate cyclase
CNO08_RS07715	COG3300	MHYT domain
CNO08_RS07725	COG1253	flavin adenine dinucleotide binding
CNO08_RS07735	COG0306	phosphate transporter
CNO08_RS07760	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CNO08_RS07795	COG3590	peptidase
CNO08_RS07800	COG3590	peptidase
CNO08_RS07805	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CNO08_RS07820	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CNO08_RS07840	COG1028	Short-chain dehydrogenase reductase Sdr
CNO08_RS07850	COG1131	(ABC) transporter
CNO08_RS07860	COG0513	Belongs to the DEAD box helicase family
CNO08_RS07875	COG0419	ATPase involved in DNA repair
CNO08_RS07885	COG2203	Gaf domain
CNO08_RS07885	COG4251	negative regulation of phosphorylation
CNO08_RS07885	COG5001	Diguanylate cyclase
CNO08_RS07885	COG3706	GGDEF domain
CNO08_RS07905	COG3275	phosphorelay sensor kinase activity
CNO08_RS07915	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CNO08_RS07940	COG3118	belongs to the thioredoxin family
CNO08_RS07985	COG0495	leucyl-tRNA aminoacylation
CNO08_RS08005	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CNO08_RS08080	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CNO08_RS08110	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CNO08_RS08120	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CNO08_RS08140	COG0424	maF-like protein
CNO08_RS08150	COG3164	Protein of unknown function
CNO08_RS08155	COG0312	modulator of DNA gyrase
CNO08_RS08160	COG3028	Belongs to the UPF0307 family
CNO08_RS08165	COG0312	modulator of DNA gyrase
CNO08_RS08185	COG0142	geranyltranstransferase activity
CNO08_RS08190	COG1722	exodeoxyribonuclease VII activity
CNO08_RS08195	COG0037	tRNA processing
CNO08_RS08200	COG1902	pentaerythritol trinitrate reductase activity
CNO08_RS08225	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CNO08_RS08240	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CNO08_RS08265	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CNO08_RS08270	COG0575	Belongs to the CDS family
CNO08_RS08275	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CNO08_RS08320	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CNO08_RS08325	COG0052	Belongs to the universal ribosomal protein uS2 family
CNO08_RS08330	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CNO08_RS08335	COG0024	Methionine aminopeptidase
CNO08_RS08370	COG1393	Belongs to the ArsC family
CNO08_RS08375	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CNO08_RS08390	COG0367	asparagine synthase
CNO08_RS08415	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CNO08_RS08415	COG0475	glutathione-regulated potassium exporter activity
CNO08_RS08455	COG0557	exoribonuclease II activity
CNO08_RS08460	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CNO08_RS08470	COG2076	Multidrug Resistance protein
CNO08_RS08490	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CNO08_RS08500	COG3220	belongs to the UPF0276 family
CNO08_RS08510	COG1191	sigma factor activity
CNO08_RS08515	COG0704	Plays a role in the regulation of phosphate uptake
CNO08_RS08525	COG0581	inorganic phosphate transmembrane transporter activity
CNO08_RS08530	COG0573	inorganic phosphate transmembrane transporter activity
CNO08_RS08535	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CNO08_RS08550	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CNO08_RS08560	COG1024	Enoyl-CoA hydratase
CNO08_RS08605	COG0824	Thioesterase
CNO08_RS08610	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CNO08_RS08620	COG1404	Belongs to the peptidase S8 family
CNO08_RS08630	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CNO08_RS08635	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CNO08_RS08640	COG0268	Binds directly to 16S ribosomal RNA
CNO08_RS08650	COG0196	riboflavin kinase activity
CNO08_RS08665	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CNO08_RS08705	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CNO08_RS08720	COG1024	Enoyl-CoA hydratase
CNO08_RS08720	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CNO08_RS08730	COG2814	Major facilitator Superfamily
CNO08_RS08735	COG1566	PFAM secretion protein HlyD family protein
CNO08_RS08750	COG4137	Cytochrome C assembly protein
CNO08_RS08755	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CNO08_RS08760	COG0228	four-way junction DNA binding
CNO08_RS08770	COG0336	Belongs to the RNA methyltransferase TrmD family
CNO08_RS08775	COG0335	large ribosomal subunit rRNA binding
CNO08_RS08790	COG0534	Mate efflux family protein
CNO08_RS08810	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CNO08_RS08830	COG0542	response to heat
CNO08_RS08835	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CNO08_RS08875	COG0531	amino acid
CNO08_RS08885	COG0477	Major facilitator Superfamily
CNO08_RS08890	COG2130	NADP-dependent
CNO08_RS08925	COG0010	Belongs to the arginase family
CNO08_RS08935	COG1546	Belongs to the CinA family
CNO08_RS08940	COG0456	acetyltransferase
CNO08_RS08940	COG1846	Transcriptional regulator
CNO08_RS08945	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CNO08_RS08950	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CNO08_RS08955	COG2137	regulation of response to DNA damage stimulus
CNO08_RS08960	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CNO08_RS08965	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CNO08_RS08980	COG0745	RESPONSE REGULATOR receiver
CNO08_RS08985	COG2205	protein histidine kinase activity
CNO08_RS08995	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CNO08_RS09000	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CNO08_RS09020	COG0351	phosphomethylpyrimidine kinase
CNO08_RS09030	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CNO08_RS09035	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CNO08_RS09045	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CNO08_RS09060	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CNO08_RS09070	COG0617	tRNA 3'-terminal CCA addition
CNO08_RS09075	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CNO08_RS09080	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CNO08_RS09085	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CNO08_RS09090	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CNO08_RS09095	COG0166	Belongs to the GPI family
CNO08_RS09100	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CNO08_RS09105	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CNO08_RS09105	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CNO08_RS09110	COG0802	atpase or kinase
CNO08_RS09115	COG0860	N-Acetylmuramoyl-L-alanine amidase
CNO08_RS09125	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CNO08_RS09140	COG2878	Part of a membrane complex involved in electron transport
CNO08_RS09145	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CNO08_RS09145	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CNO08_RS09160	COG0489	protein tyrosine kinase activity
CNO08_RS09165	COG0717	Belongs to the dCTP deaminase family
CNO08_RS09170	COG1714	RDD family
CNO08_RS09180	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CNO08_RS09210	COG0515	serine threonine protein kinase
CNO08_RS09215	COG0515	serine threonine protein kinase
CNO08_RS09225	COG1984	allophanate hydrolase subunit 2
CNO08_RS09230	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CNO08_RS09240	COG0412	Dienelactone hydrolase
CNO08_RS09250	COG2081	HI0933 family
CNO08_RS09255	COG4681	YaeQ
CNO08_RS09260	COG0564	pseudouridine synthase activity
CNO08_RS09265	COG0519	Catalyzes the synthesis of GMP from XMP
CNO08_RS09265	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CNO08_RS09275	COG1349	DNA-binding transcription factor activity
CNO08_RS09280	COG2223	nitrite transmembrane transporter activity
CNO08_RS09295	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CNO08_RS09310	COG0488	(ABC) transporter
CNO08_RS09365	COG0625	glutathione transferase activity
CNO08_RS09405	COG1187	pseudouridine synthase activity
CNO08_RS09415	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CNO08_RS09420	COG0531	amino acid
CNO08_RS09435	COG0584	glycerophosphoryl diester phosphodiesterase
CNO08_RS09440	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CNO08_RS09450	COG5295	Hep Hag repeat protein
CNO08_RS09460	COG0339	signal peptide processing
CNO08_RS09475	COG4771	TonB-dependent receptor
CNO08_RS09480	COG0386	Belongs to the glutathione peroxidase family
CNO08_RS09495	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CNO08_RS09505	COG2183	response to ionizing radiation
CNO08_RS09510	COG2133	pyrroloquinoline quinone binding
CNO08_RS09545	COG3621	Patatin-like phospholipase
CNO08_RS09565	COG4104	PAAR repeat-containing protein
CNO08_RS09580	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CNO08_RS09585	COG0084	hydrolase, TatD family'
CNO08_RS09600	COG1960	acyl-CoA dehydrogenase activity
CNO08_RS09610	COG0625	glutathione transferase activity
CNO08_RS09615	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CNO08_RS09630	COG2009	succinate dehydrogenase
CNO08_RS09635	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CNO08_RS09665	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CNO08_RS09675	COG4591	ABC-type transport system involved in lipoprotein release permease component
CNO08_RS09690	COG0811	peptide transport
CNO08_RS09695	COG0848	biopolymer transport protein
CNO08_RS09705	COG1663	tetraacyldisaccharide 4'-kinase activity
CNO08_RS09710	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CNO08_RS09715	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CNO08_RS09720	COG0322	excinuclease ABC activity
CNO08_RS09760	COG2205	protein histidine kinase activity
CNO08_RS09795	COG2011	ABC-type metal ion transport system permease component
CNO08_RS09800	COG1464	Belongs to the NlpA lipoprotein family
CNO08_RS09870	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CNO08_RS09900	COG3706	GGDEF domain
CNO08_RS09910	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CNO08_RS09915	COG0069	glutamate synthase activity
CNO08_RS09920	COG1393	Belongs to the ArsC family
CNO08_RS09955	COG4221	oxidoreductase activity
CNO08_RS09985	COG1716	ATPase activity
CNO08_RS09990	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
CNO08_RS09995	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CNO08_RS10000	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CNO08_RS10005	COG0077	Prephenate dehydratase
CNO08_RS10005	COG1605	Chorismate mutase
CNO08_RS10040	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CNO08_RS10050	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CNO08_RS10055	COG0583	DNA-binding transcription factor activity
CNO08_RS10095	COG1280	lysine exporter protein (LysE YggA)
CNO08_RS10105	COG0515	serine threonine protein kinase
CNO08_RS10110	COG1132	(ABC) transporter
CNO08_RS10120	COG1136	(ABC) transporter
CNO08_RS10120	COG0577	efflux transmembrane transporter activity
CNO08_RS10130	COG2207	Transcriptional regulator
CNO08_RS10135	COG4221	oxidoreductase activity
CNO08_RS10155	COG1530	ribonuclease E activity
CNO08_RS10160	COG0564	pseudouridine synthase activity
CNO08_RS10180	COG0316	Belongs to the HesB IscA family
CNO08_RS10180	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CNO08_RS10200	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CNO08_RS10230	COG1309	transcriptional regulator
CNO08_RS10235	COG2130	NADP-dependent
CNO08_RS10245	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CNO08_RS10250	COG2957	Belongs to the agmatine deiminase family
CNO08_RS10260	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CNO08_RS10270	COG0539	negative regulation of cytoplasmic translation
CNO08_RS10275	COG0776	regulation of translation
CNO08_RS10285	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CNO08_RS10290	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CNO08_RS10300	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CNO08_RS10310	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CNO08_RS10315	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CNO08_RS10330	COG0183	Belongs to the thiolase family
CNO08_RS10335	COG1024	Enoyl-CoA hydratase
CNO08_RS10335	COG1250	3-hydroxyacyl-CoA dehydrogenase
CNO08_RS10345	COG0105	UTP biosynthetic process
CNO08_RS10370	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CNO08_RS10375	COG1160	GTP binding
CNO08_RS10380	COG0746	molybdenum cofactor guanylyltransferase activity
CNO08_RS10390	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CNO08_RS10415	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CNO08_RS10430	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CNO08_RS10430	COG0519	Catalyzes the synthesis of GMP from XMP
CNO08_RS10445	COG1309	transcriptional regulator
CNO08_RS10485	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CNO08_RS10490	COG0668	transmembrane transport
CNO08_RS10500	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CNO08_RS10540	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CNO08_RS10560	COG2610	gluconate transmembrane transporter activity
CNO08_RS10565	COG4771	TonB-dependent receptor
CNO08_RS10570	COG2205	protein histidine kinase activity
CNO08_RS10590	COG1183	phosphatidylcholine synthase activity
CNO08_RS10600	COG3243	poly(R)-hydroxyalkanoic acid synthase
CNO08_RS10670	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CNO08_RS10690	COG1138	Cytochrome C-type biogenesis protein
CNO08_RS10695	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
CNO08_RS10725	COG0436	Aminotransferase
CNO08_RS10830	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CNO08_RS10845	COG1090	epimerase
CNO08_RS10880	COG1960	acyl-CoA dehydrogenase activity
CNO08_RS10885	COG1024	Enoyl-CoA hydratase
CNO08_RS10890	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CNO08_RS10900	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CNO08_RS10905	COG1858	cytochrome C peroxidase
CNO08_RS10940	COG4251	negative regulation of phosphorylation
CNO08_RS10950	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CNO08_RS10965	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CNO08_RS10970	COG0735	belongs to the Fur family
CNO08_RS10975	COG0497	DNA recombination
CNO08_RS10980	COG1420	regulation of RNA biosynthetic process
CNO08_RS10985	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CNO08_RS10990	COG0443	Heat shock 70 kDa protein
CNO08_RS11015	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CNO08_RS11020	COG0505	Belongs to the CarA family
CNO08_RS11035	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CNO08_RS11040	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CNO08_RS11060	COG1446	asparaginase
CNO08_RS11065	COG3142	Participates in the control of copper homeostasis
CNO08_RS11080	COG3537	Alpha-1,2-mannosidase
CNO08_RS11085	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CNO08_RS11090	COG4206	TonB-dependent receptor
CNO08_RS11100	COG4676	Protein conserved in bacteria
CNO08_RS11120	COG0318	PFAM AMP-dependent synthetase and ligase
CNO08_RS11135	COG0583	DNA-binding transcription factor activity
CNO08_RS11140	COG2828	Protein conserved in bacteria
CNO08_RS11150	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CNO08_RS11155	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CNO08_RS11175	COG1049	propionate catabolic process, 2-methylcitrate cycle
CNO08_RS11185	COG2915	High frequency lysogenization protein hflD homolog
CNO08_RS11190	COG0482	sulfurtransferase activity
CNO08_RS11210	COG0542	response to heat
CNO08_RS11240	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CNO08_RS11255	COG0492	ferredoxin-NADP+ reductase activity
CNO08_RS11260	COG0686	Belongs to the AlaDH PNT family
CNO08_RS11265	COG1674	ftsk spoiiie
CNO08_RS11290	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CNO08_RS11300	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CNO08_RS11305	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CNO08_RS11330	COG2831	hemolysin activation secretion protein
CNO08_RS11335	COG0811	peptide transport
CNO08_RS11385	COG1177	transmembrane transport
CNO08_RS11395	COG3842	ATPase activity
CNO08_RS11400	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CNO08_RS11410	COG0583	DNA-binding transcription factor activity
CNO08_RS11440	COG0789	Transcriptional regulator
CNO08_RS11445	COG2217	Heavy metal translocating P-type atpase
CNO08_RS11450	COG1201	RNA secondary structure unwinding
CNO08_RS11475	COG1285	pathogenesis
CNO08_RS11510	COG2223	nitrite transmembrane transporter activity
CNO08_RS11515	COG2207	Transcriptional regulator
CNO08_RS11650	COG2204	response regulator
CNO08_RS11680	COG3409	Peptidoglycan-binding domain 1 protein
CNO08_RS11680	COG3773	Cell wall hydrolase
CNO08_RS11705	COG2197	response regulator
CNO08_RS11710	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
CNO08_RS11725	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CNO08_RS11730	COG1845	cytochrome c oxidase, subunit III
CNO08_RS11735	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CNO08_RS11740	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CNO08_RS11745	COG0477	Major facilitator Superfamily
CNO08_RS11770	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CNO08_RS11775	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CNO08_RS11780	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CNO08_RS11805	COG3135	benzoate transporter
CNO08_RS11825	COG1063	alcohol dehydrogenase
CNO08_RS11855	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CNO08_RS11860	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CNO08_RS11865	COG0489	protein tyrosine kinase activity
CNO08_RS11865	COG3206	protein involved in exopolysaccharide biosynthesis
CNO08_RS11885	COG0840	transmembrane signaling receptor activity
CNO08_RS11915	COG5001	Diguanylate cyclase
CNO08_RS11915	COG4251	negative regulation of phosphorylation
CNO08_RS11915	COG3706	GGDEF domain
CNO08_RS11915	COG2203	Gaf domain
CNO08_RS11990	COG3209	COG3209 Rhs family protein
CNO08_RS12030	COG3179	chitinase
CNO08_RS12115	COG0579	oxidoreductase
CNO08_RS12125	COG3591	Belongs to the peptidase S1B family
CNO08_RS12230	COG4774	siderophore transport
CNO08_RS12235	COG0738	Major facilitator superfamily
CNO08_RS12240	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CNO08_RS12245	COG1846	Transcriptional regulator
CNO08_RS12245	COG1940	carbohydrate kinase activity
CNO08_RS12260	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CNO08_RS12275	COG1132	(ABC) transporter
CNO08_RS12330	COG1028	Short-chain dehydrogenase reductase Sdr
CNO08_RS12340	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CNO08_RS12345	COG1535	isochorismatase
CNO08_RS12345	COG3433	isochorismatase activity
CNO08_RS12350	COG1021	2,3-dihydroxybenzoate-AMP ligase
CNO08_RS12355	COG1169	isochorismate synthase
CNO08_RS12375	COG2132	Multicopper oxidase
CNO08_RS12390	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CNO08_RS12395	COG2205	protein histidine kinase activity
CNO08_RS12395	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CNO08_RS12400	COG2197	response regulator
CNO08_RS12405	COG2885	chlorophyll binding
CNO08_RS12410	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CNO08_RS12415	COG0415	Belongs to the DNA photolyase family
CNO08_RS12420	COG1404	Belongs to the peptidase S8 family
CNO08_RS12420	COG1404	Belongs to the peptidase S8 family
CNO08_RS12425	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CNO08_RS12430	COG3134	Outer membrane lipoprotein
CNO08_RS12435	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CNO08_RS12435	COG2022	thiamine diphosphate biosynthetic process
CNO08_RS12465	COG0305	Participates in initiation and elongation during chromosome replication
CNO08_RS12470	COG0359	binds to the 23S rRNA
CNO08_RS12475	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CNO08_RS12480	COG0360	Binds together with S18 to 16S ribosomal RNA
CNO08_RS12490	COG0316	Belongs to the HesB IscA family
CNO08_RS12500	COG0017	Asparaginyl-tRNA synthetase
CNO08_RS12545	COG0714	Associated with various cellular activities
CNO08_RS12580	COG0288	reversible hydration of carbon dioxide
CNO08_RS12605	COG3844	kynureninase activity
CNO08_RS12615	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CNO08_RS12620	COG2925	Exonuclease
CNO08_RS12630	COG2814	Major facilitator Superfamily
CNO08_RS12660	COG1113	amino acid transport
CNO08_RS12680	COG2902	Dehydrogenase
CNO08_RS12685	COG1960	acyl-CoA dehydrogenase activity
CNO08_RS12715	COG1309	transcriptional regulator
CNO08_RS12720	COG4221	oxidoreductase activity
CNO08_RS12735	COG2900	Belongs to the SlyX family
CNO08_RS12750	COG0545	Peptidyl-prolyl cis-trans isomerase
CNO08_RS12755	COG0386	Belongs to the glutathione peroxidase family
CNO08_RS12765	COG1725	Transcriptional regulator
CNO08_RS12770	COG1131	(ABC) transporter
CNO08_RS12795	COG4682	membrane
CNO08_RS12810	COG2017	converts alpha-aldose to the beta-anomer
CNO08_RS12835	COG4948	Mandelate Racemase Muconate Lactonizing
CNO08_RS12840	COG0800	Aldolase
CNO08_RS12845	COG1028	Short-chain dehydrogenase reductase Sdr
CNO08_RS12850	COG3250	beta-galactosidase activity
CNO08_RS12890	COG2850	peptidyl-arginine hydroxylation
CNO08_RS12900	COG0567	Dehydrogenase, E1 component
CNO08_RS12905	COG0508	dehydrogenase complex catalyzes the overall conversion of
CNO08_RS12925	COG0604	alcohol dehydrogenase
CNO08_RS12950	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CNO08_RS12960	COG4953	penicillin-binding protein 1C
CNO08_RS12975	COG2373	Large extracellular alpha-helical protein
CNO08_RS12985	COG3227	Zinc metalloprotease (Elastase)
CNO08_RS12990	COG3227	Zinc metalloprotease (Elastase)
CNO08_RS13000	COG5507	3-demethylubiquinone-9 3-methyltransferase
CNO08_RS13010	COG1404	Belongs to the peptidase S8 family
CNO08_RS13015	COG2353	YceI-like domain
CNO08_RS13030	COG3718	enzyme involved in inositol metabolism
CNO08_RS13040	COG3962	Belongs to the TPP enzyme family
CNO08_RS13045	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CNO08_RS13050	COG1129	ABC transporter
CNO08_RS13055	COG1172	Belongs to the binding-protein-dependent transport system permease family
CNO08_RS13065	COG1737	Transcriptional regulator
CNO08_RS13070	COG0673	inositol 2-dehydrogenase activity
CNO08_RS13075	COG0673	inositol 2-dehydrogenase activity
CNO08_RS13085	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CNO08_RS13100	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
CNO08_RS13105	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CNO08_RS13115	COG3115	cell septum assembly
CNO08_RS13135	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CNO08_RS13165	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CNO08_RS13185	COG3842	ATPase activity
CNO08_RS13190	COG2723	6-phospho-beta-galactosidase activity
CNO08_RS13195	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CNO08_RS13205	COG0363	glucosamine-6-phosphate deaminase activity
CNO08_RS13215	COG0395	ABC-type sugar transport system, permease component
CNO08_RS13220	COG1175	transmembrane transport
CNO08_RS13250	COG2350	Protein conserved in bacteria
CNO08_RS13265	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CNO08_RS13270	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CNO08_RS13275	COG1187	pseudouridine synthase activity
CNO08_RS13310	COG3505	Type IV secretory pathway VirD4
CNO08_RS13365	COG4191	Histidine kinase
CNO08_RS13400	COG1028	Short-chain dehydrogenase reductase Sdr
CNO08_RS13405	COG1028	Short-chain dehydrogenase reductase Sdr
CNO08_RS13470	COG1185	polyribonucleotide nucleotidyltransferase activity
CNO08_RS13495	COG0195	Participates in both transcription termination and antitermination
CNO08_RS13500	COG0779	Required for maturation of 30S ribosomal subunits
CNO08_RS13510	COG1007	ATP synthesis coupled electron transport
CNO08_RS13535	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CNO08_RS13540	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CNO08_RS13550	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CNO08_RS13555	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CNO08_RS13560	COG0649	NAD binding
CNO08_RS13565	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CNO08_RS13570	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CNO08_RS13575	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CNO08_RS13590	COG0149	triose-phosphate isomerase activity
CNO08_RS13620	COG3083	sulfuric ester hydrolase activity
CNO08_RS13630	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CNO08_RS13635	COG0159	tryptophan synthase activity
CNO08_RS13640	COG0133	tryptophan synthase activity
CNO08_RS13650	COG0101	tRNA pseudouridine synthase activity
CNO08_RS13660	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CNO08_RS13670	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CNO08_RS13675	COG2890	protein-(glutamine-N5) methyltransferase activity
CNO08_RS13680	COG1999	signal sequence binding
CNO08_RS13685	COG0688	phosphatidylethanolamine metabolic process
CNO08_RS13710	COG0433	COG0433 Predicted ATPase
CNO08_RS13715	COG3015	lipoprotein NlpE involved in copper resistance
CNO08_RS13720	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CNO08_RS13770	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CNO08_RS13780	COG2373	Large extracellular alpha-helical protein
CNO08_RS13785	COG4953	penicillin-binding protein 1C
CNO08_RS13805	COG1278	Cold shock
CNO08_RS13810	COG0583	DNA-binding transcription factor activity
CNO08_RS13815	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CNO08_RS13820	COG2081	HI0933 family
CNO08_RS13830	COG1054	Belongs to the UPF0176 family
CNO08_RS13905	COG0438	transferase activity, transferring glycosyl groups
CNO08_RS13930	COG1451	nucleotide metabolic process
CNO08_RS13940	COG0477	Major facilitator Superfamily
CNO08_RS13945	COG0673	inositol 2-dehydrogenase activity
CNO08_RS13950	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CNO08_RS13955	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CNO08_RS13970	COG0251	oxidation-reduction process
CNO08_RS13995	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
CNO08_RS14045	COG1309	transcriptional regulator
CNO08_RS14080	COG3634	alkyl hydroperoxide reductase activity
CNO08_RS14085	COG1959	2 iron, 2 sulfur cluster binding
CNO08_RS14115	COG0596	Alpha beta hydrolase
CNO08_RS14190	COG1238	metal cluster binding
CNO08_RS14195	COG3590	peptidase
CNO08_RS14200	COG1074	ATP-dependent DNA helicase activity
CNO08_RS14295	COG1703	isobutyryl-CoA mutase activity
CNO08_RS14295	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CNO08_RS14295	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CNO08_RS14315	COG1960	acyl-CoA dehydrogenase activity
CNO08_RS14325	COG0183	Belongs to the thiolase family
CNO08_RS14345	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CNO08_RS14350	COG0443	Heat shock 70 kDa protein
CNO08_RS14355	COG0484	heat shock protein binding
CNO08_RS14400	COG1024	Enoyl-CoA hydratase
CNO08_RS14540	COG0156	8-amino-7-oxononanoate synthase activity
CNO08_RS14570	COG2130	NADP-dependent
CNO08_RS14575	COG2936	dipeptidyl-peptidase activity
CNO08_RS14585	COG2267	carboxylic ester hydrolase activity
CNO08_RS14590	COG3708	Transcriptional regulator
CNO08_RS14590	COG2207	Transcriptional regulator
CNO08_RS14595	COG0456	acetyltransferase
CNO08_RS14605	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CNO08_RS14620	COG3511	phospholipase C
CNO08_RS14630	COG0531	amino acid
CNO08_RS14635	COG0531	amino acid
CNO08_RS14640	COG0235	Class ii aldolase
CNO08_RS14655	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
CNO08_RS14680	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CNO08_RS14680	COG0140	phosphoribosyl-ATP diphosphatase activity
CNO08_RS14690	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CNO08_RS14695	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CNO08_RS14705	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CNO08_RS14710	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CNO08_RS14715	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CNO08_RS14735	COG2986	histidine ammonia-lyase
CNO08_RS14740	COG0124	histidyl-tRNA synthetase
CNO08_RS14755	COG0726	polysaccharide deacetylase
CNO08_RS14760	COG1215	transferase activity, transferring glycosyl groups
CNO08_RS14790	COG1649	PFAM Uncharacterised BCR, COG1649
CNO08_RS14790	COG0726	polysaccharide deacetylase
CNO08_RS14795	COG1215	transferase activity, transferring glycosyl groups
CNO08_RS14855	COG0165	Argininosuccinate lyase
CNO08_RS14860	COG0442	prolyl-tRNA aminoacylation
CNO08_RS14865	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CNO08_RS14875	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CNO08_RS14880	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CNO08_RS14885	COG0137	argininosuccinate synthase activity
CNO08_RS14890	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CNO08_RS14905	COG2166	iron-sulfur cluster assembly
CNO08_RS14935	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CNO08_RS14955	COG1469	GTP cyclohydrolase I activity
CNO08_RS14975	COG0402	S-adenosylhomocysteine deaminase activity
CNO08_RS14985	COG1509	lysine 2,3-aminomutase activity
CNO08_RS15000	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CNO08_RS15005	COG1028	Short-chain dehydrogenase reductase Sdr
CNO08_RS15010	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
CNO08_RS15015	COG1028	Short-chain dehydrogenase reductase Sdr
CNO08_RS15080	COG2205	protein histidine kinase activity
CNO08_RS15085	COG0745	RESPONSE REGULATOR receiver
CNO08_RS15105	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CNO08_RS15110	COG0642	Histidine kinase
CNO08_RS15165	COG1012	belongs to the aldehyde dehydrogenase family
CNO08_RS15210	COG0167	dihydroorotate dehydrogenase activity
CNO08_RS15215	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CNO08_RS15245	COG1404	Belongs to the peptidase S8 family
CNO08_RS15255	COG1404	Belongs to the peptidase S8 family
CNO08_RS15260	COG0671	phosphoesterase, PA-phosphatase related
CNO08_RS15265	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CNO08_RS15280	COG1012	belongs to the aldehyde dehydrogenase family
CNO08_RS15285	COG2304	oxidoreductase activity
CNO08_RS15290	COG5001	Diguanylate cyclase
CNO08_RS15310	COG1132	(ABC) transporter
CNO08_RS15360	COG1960	acyl-CoA dehydrogenase activity
CNO08_RS15365	COG1278	Cold shock
CNO08_RS15370	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CNO08_RS15375	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CNO08_RS15380	COG1472	Belongs to the glycosyl hydrolase 3 family
CNO08_RS15385	COG2954	triphosphatase activity
CNO08_RS15415	COG1381	Involved in DNA repair and RecF pathway recombination
CNO08_RS15425	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CNO08_RS15440	COG0681	Belongs to the peptidase S26 family
CNO08_RS15445	COG0481	GTPase activity
CNO08_RS15450	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CNO08_RS15465	COG1024	Enoyl-CoA hydratase
CNO08_RS15465	COG1250	3-hydroxyacyl-CoA dehydrogenase
CNO08_RS15485	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CNO08_RS15490	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CNO08_RS15500	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CNO08_RS15510	COG1028	Short-chain dehydrogenase reductase Sdr
CNO08_RS15515	COG1028	Short-chain dehydrogenase reductase Sdr
CNO08_RS15525	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CNO08_RS15535	COG1399	metal-binding, possibly nucleic acid-binding protein
CNO08_RS15555	COG0714	Associated with various cellular activities
CNO08_RS15585	COG0537	adenosine 5'-monophosphoramidase activity
CNO08_RS15640	COG3391	amine dehydrogenase activity
CNO08_RS15650	COG0314	molybdopterin synthase activity
CNO08_RS15675	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CNO08_RS15685	COG0859	PFAM glycosyl transferase family 9
CNO08_RS15710	COG0631	protein serine/threonine phosphatase activity
CNO08_RS15715	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CNO08_RS15730	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CNO08_RS15740	COG1757	Na H antiporter
CNO08_RS15745	COG0473	3-isopropylmalate dehydrogenase activity
CNO08_RS15760	COG4783	chaperone-mediated protein folding
CNO08_RS15775	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CNO08_RS15780	COG0248	Ppx GppA phosphatase
CNO08_RS15785	COG0318	PFAM AMP-dependent synthetase and ligase
CNO08_RS15805	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
CNO08_RS15810	COG0438	transferase activity, transferring glycosyl groups
CNO08_RS15815	COG0671	phosphoesterase, PA-phosphatase related
CNO08_RS15830	COG4452	Inner membrane protein CreD
CNO08_RS15835	COG2205	protein histidine kinase activity
CNO08_RS15840	COG0745	RESPONSE REGULATOR receiver
CNO08_RS15845	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CNO08_RS15860	COG3878	Protein conserved in bacteria
CNO08_RS15885	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CNO08_RS15905	COG1741	Belongs to the pirin family
CNO08_RS15915	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CNO08_RS15930	COG3963	phosphatidate phosphatase activity
CNO08_RS15935	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CNO08_RS15935	COG0116	Belongs to the methyltransferase superfamily
CNO08_RS15960	COG1946	Acyl-CoA thioesterase
CNO08_RS15975	COG1595	DNA-templated transcription, initiation
CNO08_RS15990	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CNO08_RS16030	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CNO08_RS16065	COG2226	methyltransferase
CNO08_RS16070	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CNO08_RS16085	COG2197	response regulator
CNO08_RS16090	COG4585	Histidine kinase
CNO08_RS16105	COG2894	cell division
CNO08_RS16110	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CNO08_RS16155	COG3710	Transcriptional regulator
CNO08_RS16190	COG4245	von Willebrand factor, type A
CNO08_RS16205	COG2814	Major facilitator Superfamily
CNO08_RS16210	COG0346	lactoylglutathione lyase activity
CNO08_RS16215	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CNO08_RS16215	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CNO08_RS16255	COG1960	acyl-CoA dehydrogenase activity
CNO08_RS16280	COG3275	phosphorelay sensor kinase activity
CNO08_RS16315	COG4948	Mandelate Racemase Muconate Lactonizing
CNO08_RS16335	COG3949	Membrane
CNO08_RS16365	COG0583	DNA-binding transcription factor activity
CNO08_RS16380	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CNO08_RS16440	COG0330	HflC and HflK could
CNO08_RS16445	COG0330	HflC and HflK could
CNO08_RS16450	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CNO08_RS16455	COG1923	regulation of RNA biosynthetic process
CNO08_RS16460	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CNO08_RS16465	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CNO08_RS16475	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CNO08_RS16480	COG1534	Rna-binding protein
CNO08_RS16515	COG1238	metal cluster binding
CNO08_RS16525	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CNO08_RS16530	COG2197	response regulator
CNO08_RS16550	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CNO08_RS16555	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CNO08_RS16565	COG0148	phosphopyruvate hydratase activity
CNO08_RS16575	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CNO08_RS16585	COG0504	CTP synthase activity
CNO08_RS16625	COG3214	Protein conserved in bacteria
CNO08_RS16635	COG1506	peptidase
CNO08_RS16635	COG4946	Tricorn protease homolog
CNO08_RS16635	COG0823	Involved in the tonB-independent uptake of proteins
CNO08_RS16645	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CNO08_RS16660	COG2311	Membrane
CNO08_RS16670	COG1047	Peptidyl-prolyl cis-trans
CNO08_RS16675	COG0791	NLP P60 protein
CNO08_RS16680	COG0791	NLP P60 protein
CNO08_RS16695	COG0612	Peptidase, M16
CNO08_RS16700	COG0612	Peptidase, M16
CNO08_RS16705	COG1051	belongs to the nudix hydrolase family
CNO08_RS16745	COG1301	dicarboxylic acid transport
CNO08_RS16755	COG1981	membrane
CNO08_RS16840	COG2223	nitrite transmembrane transporter activity
CNO08_RS16850	COG0243	molybdopterin cofactor binding
CNO08_RS16880	COG0667	Aldo Keto reductase
CNO08_RS16890	COG0583	DNA-binding transcription factor activity
CNO08_RS16920	COG4771	TonB-dependent receptor
CNO08_RS16940	COG0513	Belongs to the DEAD box helicase family
CNO08_RS16950	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CNO08_RS16980	COG0640	Transcriptional regulator
CNO08_RS16985	COG3239	Fatty acid desaturase
CNO08_RS16990	COG2827	Endonuclease containing a URI domain
CNO08_RS17000	COG0604	alcohol dehydrogenase
CNO08_RS17000	COG3321	synthase
CNO08_RS17020	COG1056	cytidyltransferase-related domain
CNO08_RS17020	COG1051	belongs to the nudix hydrolase family
CNO08_RS17050	COG3321	synthase
CNO08_RS17050	COG0604	alcohol dehydrogenase
CNO08_RS17050	COG1028	Short-chain dehydrogenase reductase Sdr
CNO08_RS17060	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CNO08_RS17095	COG1309	transcriptional regulator
CNO08_RS17120	COG5297	Belongs to the glycosyl hydrolase family 6
CNO08_RS17120	COG4733	cellulase activity
CNO08_RS17130	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CNO08_RS17140	COG1228	amidohydrolase
CNO08_RS17185	COG0735	belongs to the Fur family
CNO08_RS17195	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CNO08_RS17230	COG2833	Protein of unknown function (DUF455)
CNO08_RS17250	COG0285	dihydrofolate synthase activity
CNO08_RS17260	COG0406	alpha-ribazole phosphatase activity
CNO08_RS17265	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CNO08_RS17300	COG1063	alcohol dehydrogenase
CNO08_RS17345	COG3384	dioxygenase
CNO08_RS17350	COG0583	DNA-binding transcription factor activity
CNO08_RS17355	COG2814	Major facilitator Superfamily
CNO08_RS17360	COG0583	DNA-binding transcription factor activity
CNO08_RS17370	COG0604	alcohol dehydrogenase
CNO08_RS17375	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CNO08_RS17380	COG1196	nuclear chromosome segregation
CNO08_RS17395	COG1902	pentaerythritol trinitrate reductase activity
CNO08_RS17395	COG0446	pyridine nucleotide-disulphide oxidoreductase
CNO08_RS17405	COG0625	glutathione transferase activity
CNO08_RS17440	COG0477	Major facilitator Superfamily
CNO08_RS17445	COG1301	dicarboxylic acid transport
CNO08_RS17455	COG5002	protein histidine kinase activity
CNO08_RS17465	COG0039	L-malate dehydrogenase activity
CNO08_RS17485	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CNO08_RS17490	COG1217	gtp-binding protein TYPA
CNO08_RS17515	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
CNO08_RS17530	COG0154	amidase activity
CNO08_RS17540	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CNO08_RS17555	COG0202	RNA polymerase activity
CNO08_RS17560	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CNO08_RS17575	COG0201	protein transport
CNO08_RS17580	COG0200	Binds to the 23S rRNA
CNO08_RS17585	COG1841	ribosomal large subunit assembly
CNO08_RS17595	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CNO08_RS17610	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CNO08_RS17620	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CNO08_RS17630	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CNO08_RS17635	COG0255	Belongs to the universal ribosomal protein uL29 family
CNO08_RS17640	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CNO08_RS17645	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CNO08_RS17655	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CNO08_RS17660	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CNO08_RS17665	COG0089	rRNA binding
CNO08_RS17675	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CNO08_RS17680	COG0051	transcription antitermination factor activity, RNA binding
CNO08_RS17685	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CNO08_RS17690	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CNO08_RS17695	COG0049	tRNA binding
CNO08_RS17705	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CNO08_RS17710	COG0085	RNA polymerase activity
CNO08_RS17715	COG0222	ribosome binding
CNO08_RS17725	COG0081	regulation of translation
CNO08_RS17730	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CNO08_RS17735	COG0250	Participates in transcription elongation, termination and antitermination
CNO08_RS17750	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CNO08_RS17770	COG0012	GTP binding
CNO08_RS17775	COG0193	aminoacyl-tRNA hydrolase activity
CNO08_RS17785	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CNO08_RS17800	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CNO08_RS17810	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CNO08_RS17815	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CNO08_RS17830	COG0521	Mo-molybdopterin cofactor biosynthetic process
CNO08_RS17840	COG2326	polyphosphate kinase activity
CNO08_RS17875	COG1254	Belongs to the acylphosphatase family
CNO08_RS17880	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CNO08_RS17885	COG1295	ribonuclease BN
CNO08_RS17905	COG0252	asparaginase activity
CNO08_RS17945	COG3291	Pkd domain containing protein
CNO08_RS17955	COG1404	Belongs to the peptidase S8 family
CNO08_RS17960	COG1404	Belongs to the peptidase S8 family
CNO08_RS17995	COG1309	transcriptional regulator
CNO08_RS18000	COG1404	Belongs to the peptidase S8 family
CNO08_RS18010	COG1404	Belongs to the peptidase S8 family
CNO08_RS18015	COG1404	Belongs to the peptidase S8 family
CNO08_RS18020	COG1404	Belongs to the peptidase S8 family
CNO08_RS18030	COG2151	metal-sulfur cluster biosynthetic enzyme
CNO08_RS18060	COG4807	Protein conserved in bacteria
CNO08_RS18135	COG2226	methyltransferase
CNO08_RS18150	COG1215	transferase activity, transferring glycosyl groups
CNO08_RS18170	COG0438	transferase activity, transferring glycosyl groups
CNO08_RS18170	COG1216	Glycosyl transferase, family 2
CNO08_RS18190	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CNO08_RS18195	COG0450	alkyl hydroperoxide reductase
CNO08_RS18200	COG0583	DNA-binding transcription factor activity
CNO08_RS18205	COG1492	cobalamin metabolic process
CNO08_RS18250	COG0477	Major facilitator Superfamily
CNO08_RS18265	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CNO08_RS18270	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CNO08_RS18280	COG2096	Adenosyltransferase
CNO08_RS18285	COG0123	including yeast histone deacetylase and acetoin utilization protein
CNO08_RS18290	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CNO08_RS18295	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CNO08_RS18300	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CNO08_RS18305	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CNO08_RS18315	COG2967	ApaG domain
CNO08_RS18320	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CNO08_RS18325	COG3738	Protein conserved in bacteria
CNO08_RS18350	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CNO08_RS18370	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CNO08_RS18375	COG1704	LemA family
CNO08_RS18380	COG0861	Integral membrane protein TerC family
CNO08_RS18385	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CNO08_RS18390	COG0577	efflux transmembrane transporter activity
CNO08_RS18390	COG1136	(ABC) transporter
CNO08_RS18395	COG1136	(ABC) transporter
CNO08_RS18400	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CNO08_RS18410	COG0642	Histidine kinase
CNO08_RS18415	COG0745	RESPONSE REGULATOR receiver
CNO08_RS18450	COG3956	TIGRFAM MazG family protein
CNO08_RS18460	COG0494	nUDIX hydrolase
CNO08_RS18470	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CNO08_RS18480	COG2201	protein-glutamate methylesterase activity
CNO08_RS18510	COG0643	Histidine kinase
CNO08_RS18510	COG0784	Response regulator, receiver
CNO08_RS18510	COG2198	Histidine kinase
CNO08_RS18515	COG0840	transmembrane signaling receptor activity
CNO08_RS18535	COG0189	ligase activity
CNO08_RS18565	COG1199	ATP-dependent helicase activity
CNO08_RS18575	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CNO08_RS18615	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CNO08_RS18630	COG1643	Atp-dependent helicase
CNO08_RS18635	COG0783	Belongs to the Dps family
CNO08_RS18640	COG0514	ATP-dependent DNA helicase (RecQ)
CNO08_RS18720	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CNO08_RS18730	COG0602	queuosine metabolic process
CNO08_RS18740	COG2885	chlorophyll binding
CNO08_RS18745	COG0823	Involved in the tonB-independent uptake of proteins
CNO08_RS18760	COG0848	biopolymer transport protein
CNO08_RS18770	COG0824	Thioesterase
CNO08_RS18775	COG2255	four-way junction helicase activity
CNO08_RS18785	COG3158	transport of potassium into the cell
CNO08_RS18795	COG0632	four-way junction helicase activity
CNO08_RS18800	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CNO08_RS18805	COG0217	transcriptional regulatory protein
CNO08_RS18835	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CNO08_RS18850	COG0488	(ABC) transporter
CNO08_RS18865	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CNO08_RS18865	COG4651	solute:proton antiporter activity
CNO08_RS18870	COG3132	Protein of unknown function, DUF480
CNO08_RS18875	COG2207	Transcriptional regulator
CNO08_RS18900	COG1492	cobalamin metabolic process
CNO08_RS18915	COG1797	cobyrinic acid a,c-diamide synthase activity
CNO08_RS18935	COG4206	TonB-dependent receptor
CNO08_RS18940	COG1028	Short-chain dehydrogenase reductase Sdr
CNO08_RS18955	COG0542	response to heat
CNO08_RS18985	COG1496	oxidoreductase activity
CNO08_RS18990	COG0564	pseudouridine synthase activity
CNO08_RS19000	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CNO08_RS19000	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CNO08_RS19005	COG2852	Protein conserved in bacteria
CNO08_RS19015	COG0045	succinate-CoA ligase (ADP-forming) activity
CNO08_RS19055	COG2226	methyltransferase
CNO08_RS19060	COG2072	flavoprotein involved in K transport
CNO08_RS19070	COG0297	glycogen (starch) synthase activity
CNO08_RS19075	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CNO08_RS19080	COG0463	Glycosyl transferase, family 2
CNO08_RS19085	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CNO08_RS19095	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CNO08_RS19100	COG0237	dephospho-CoA kinase activity
CNO08_RS19105	COG0352	thiamine-phosphate diphosphorylase activity
CNO08_RS19115	COG0739	heme binding
CNO08_RS19140	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CNO08_RS19145	COG1181	Belongs to the D-alanine--D-alanine ligase family
CNO08_RS19150	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CNO08_RS19170	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CNO08_RS19175	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CNO08_RS19185	COG3116	cell division
CNO08_RS19195	COG2001	Belongs to the MraZ family
CNO08_RS19225	COG0792	nuclease activity
CNO08_RS19230	COG1988	membrane-bound metal-dependent
CNO08_RS19235	COG0277	FAD linked oxidase domain protein
CNO08_RS19245	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CNO08_RS19250	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CNO08_RS19255	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CNO08_RS19280	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CNO08_RS19280	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CNO08_RS19310	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CNO08_RS19320	COG0488	(ABC) transporter
CNO08_RS19330	COG0024	Methionine aminopeptidase
CNO08_RS19335	COG0284	orotidine-5'-phosphate decarboxylase activity
CNO08_RS19365	COG1450	Type ii and iii secretion system protein
CNO08_RS19380	COG3166	PFAM Fimbrial assembly family protein
CNO08_RS19385	COG3156	type II secretion system protein K
CNO08_RS19390	COG4795	General secretion pathway protein
CNO08_RS19395	COG2165	general secretion pathway protein
CNO08_RS19400	COG4970	Tfp pilus assembly protein FimT
CNO08_RS19405	COG2165	general secretion pathway protein
CNO08_RS19410	COG1459	type II secretion system
CNO08_RS19425	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CNO08_RS19435	COG0047	phosphoribosylformylglycinamidine synthase activity
CNO08_RS19435	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CNO08_RS19445	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CNO08_RS19450	COG4974	Belongs to the 'phage' integrase family
CNO08_RS19460	COG0795	lipopolysaccharide-transporting ATPase activity
CNO08_RS19470	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CNO08_RS19510	COG1183	phosphatidylcholine synthase activity
CNO08_RS19520	COG0442	prolyl-tRNA aminoacylation
CNO08_RS19535	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CNO08_RS19540	COG1127	ABC transporter
CNO08_RS19550	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CNO08_RS19550	COG3218	ABC-type transport auxiliary lipoprotein component
CNO08_RS19575	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CNO08_RS19625	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CNO08_RS19630	COG0463	Glycosyl transferase, family 2
CNO08_RS19640	COG0463	Glycosyl transferase, family 2
CNO08_RS19660	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CNO08_RS19670	COG1216	Glycosyl transferase, family 2
CNO08_RS19690	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CNO08_RS19710	COG0626	cystathionine gamma-synthase activity
CNO08_RS19740	COG0625	glutathione transferase activity
CNO08_RS19765	COG0456	acetyltransferase
CNO08_RS19775	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CNO08_RS19780	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CNO08_RS19795	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
CNO08_RS19800	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CNO08_RS19820	COG0189	ligase activity
CNO08_RS19820	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CNO08_RS19825	COG0189	ligase activity
CNO08_RS19825	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CNO08_RS19830	COG4242	Belongs to the peptidase S51 family
CNO08_RS19835	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CNO08_RS19840	COG2329	Antibiotic biosynthesis monooxygenase
CNO08_RS19845	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CNO08_RS19855	COG2205	protein histidine kinase activity
CNO08_RS19875	COG1597	lipid kinase activity
CNO08_RS19880	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CNO08_RS19895	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CNO08_RS19930	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CNO08_RS19935	COG0530	calcium, potassium:sodium antiporter activity
CNO08_RS19965	COG3104	oligopeptide transport
CNO08_RS19970	COG3483	tryptophan 2,3-dioxygenase activity
CNO08_RS19985	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CNO08_RS20000	COG0508	dehydrogenase complex catalyzes the overall conversion of
CNO08_RS20010	COG4991	sh3 domain protein
CNO08_RS20040	COG0180	Tryptophanyl-tRNA synthetase
CNO08_RS20050	COG3237	CsbD-like
CNO08_RS20060	COG0010	Belongs to the arginase family
CNO08_RS20080	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CNO08_RS20090	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CNO08_RS20095	COG1307	EDD domain protein, DegV family
CNO08_RS20105	COG3228	Belongs to the MtfA family
CNO08_RS20130	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CNO08_RS20140	COG0430	RNA-3'-phosphate cyclase activity
CNO08_RS20145	COG1690	Belongs to the RtcB family
CNO08_RS20155	COG4650	regulator
CNO08_RS20175	COG5265	(ABC) transporter
CNO08_RS20225	COG2133	pyrroloquinoline quinone binding
CNO08_RS20230	COG0741	lytic transglycosylase activity
CNO08_RS20240	COG0531	amino acid
CNO08_RS20255	COG3023	N-Acetylmuramoyl-L-alanine amidase
CNO08_RS20290	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CNO08_RS20315	COG5507	3-demethylubiquinone-9 3-methyltransferase
CNO08_RS20320	COG4989	oxidoreductase activity
CNO08_RS20340	COG4977	sequence-specific DNA binding
CNO08_RS20370	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CNO08_RS20380	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CNO08_RS20405	COG0625	glutathione transferase activity
CNO08_RS20415	COG1522	sequence-specific DNA binding
CNO08_RS20425	COG0583	DNA-binding transcription factor activity
CNO08_RS20440	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CNO08_RS20480	COG1785	Belongs to the alkaline phosphatase family
CNO08_RS20560	COG0583	DNA-binding transcription factor activity
CNO08_RS20590	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CNO08_RS20590	COG1793	dna ligase
CNO08_RS20595	COG1793	dna ligase
CNO08_RS20610	COG0784	Response regulator, receiver
CNO08_RS20615	COG2205	protein histidine kinase activity
CNO08_RS20615	COG2202	Pas domain
CNO08_RS20630	COG0492	ferredoxin-NADP+ reductase activity
CNO08_RS20660	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CNO08_RS20665	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CNO08_RS20670	COG2080	2 iron, 2 sulfur cluster binding
CNO08_RS20685	COG0739	heme binding
CNO08_RS20690	COG4191	Histidine kinase
CNO08_RS20690	COG0784	Response regulator, receiver
CNO08_RS20695	COG0745	RESPONSE REGULATOR receiver
CNO08_RS20715	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CNO08_RS20745	COG0546	phosphoglycolate phosphatase activity
CNO08_RS20750	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CNO08_RS20770	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CNO08_RS20775	COG1136	(ABC) transporter
CNO08_RS20780	COG0577	efflux transmembrane transporter activity
CNO08_RS20800	COG0697	spore germination
CNO08_RS20810	COG1522	sequence-specific DNA binding
CNO08_RS20820	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CNO08_RS20820	COG2169	Transcriptional regulator
CNO08_RS20835	COG0321	lipoyl(octanoyl) transferase activity
CNO08_RS20840	COG2921	Belongs to the UPF0250 family
CNO08_RS20865	COG1686	Belongs to the peptidase S11 family
CNO08_RS20875	COG2951	lytic endotransglycosylase activity
CNO08_RS20920	COG1335	isochorismatase
CNO08_RS20925	COG0583	DNA-binding transcription factor activity
CNO08_RS20980	COG0222	ribosome binding
CNO08_RS20985	COG3469	chitinase activity
CNO08_RS20985	COG3325	Belongs to the glycosyl hydrolase 18 family
CNO08_RS21015	COG0772	Belongs to the SEDS family
CNO08_RS21020	COG0768	penicillin binding
CNO08_RS21025	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CNO08_RS21030	COG1792	Involved in formation and maintenance of cell shape
CNO08_RS21035	COG1077	Cell shape determining protein MreB Mrl
CNO08_RS21040	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CNO08_RS21070	COG0308	aminopeptidase N
CNO08_RS21075	COG1028	Short-chain dehydrogenase reductase Sdr
CNO08_RS21080	COG2226	methyltransferase
CNO08_RS21095	COG0456	acetyltransferase
CNO08_RS21095	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CNO08_RS21135	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CNO08_RS21150	COG2832	Protein of unknown function (DUF454)
CNO08_RS21160	COG1505	serine-type exopeptidase activity
CNO08_RS21215	COG0243	molybdopterin cofactor binding
CNO08_RS21225	COG0437	4 iron, 4 sulfur cluster binding
CNO08_RS21230	COG3302	dmso reductase anchor subunit
CNO08_RS21240	COG0181	hydroxymethylbilane synthase activity
CNO08_RS21250	COG2972	Histidine kinase
CNO08_RS21250	COG0745	RESPONSE REGULATOR receiver
CNO08_RS21255	COG0400	carboxylic ester hydrolase activity
CNO08_RS21295	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CNO08_RS21295	COG2010	Cytochrome c
CNO08_RS21305	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CNO08_RS21310	COG0746	molybdenum cofactor guanylyltransferase activity
CNO08_RS21320	COG0583	DNA-binding transcription factor activity
CNO08_RS21325	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CNO08_RS21330	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CNO08_RS21335	COG0346	lactoylglutathione lyase activity
CNO08_RS21360	COG4585	Histidine kinase
CNO08_RS21365	COG2311	Membrane
CNO08_RS21395	COG4774	siderophore transport
CNO08_RS21410	COG1764	response to oxidative stress
CNO08_RS21415	COG1846	Transcriptional regulator
CNO08_RS21420	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CNO08_RS21425	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
CNO08_RS21430	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CNO08_RS21450	COG4948	Mandelate Racemase Muconate Lactonizing
CNO08_RS21455	COG1737	Transcriptional regulator
CNO08_RS21485	COG0006	proline dipeptidase activity
CNO08_RS21495	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CNO08_RS21510	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CNO08_RS21515	COG3938	Belongs to the proline racemase family
CNO08_RS21535	COG0741	lytic transglycosylase activity
CNO08_RS21535	COG1196	nuclear chromosome segregation
CNO08_RS21535	COG0739	heme binding
CNO08_RS21540	COG0673	inositol 2-dehydrogenase activity
CNO08_RS21575	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CNO08_RS21615	COG0515	serine threonine protein kinase
CNO08_RS21615	COG2815	serine threonine protein kinase
CNO08_RS21645	COG0583	DNA-binding transcription factor activity
CNO08_RS21675	COG2814	Major facilitator Superfamily
CNO08_RS21715	COG0251	oxidation-reduction process
CNO08_RS21770	COG5295	Hep Hag repeat protein
CNO08_RS21770	COG5295	Hep Hag repeat protein
CNO08_RS21805	COG2814	Major facilitator Superfamily
CNO08_RS21825	COG1234	tRNA 3'-trailer cleavage
CNO08_RS21830	COG2837	iron assimilation
CNO08_RS21835	COG0484	heat shock protein binding
CNO08_RS21910	COG4447	cellulose binding
CNO08_RS21910	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CNO08_RS21915	COG0837	glucose binding
CNO08_RS21925	COG0300	oxidoreductase activity
CNO08_RS21980	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CNO08_RS21985	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CNO08_RS21985	COG2755	lipolytic protein G-D-S-L family
CNO08_RS21995	COG3275	phosphorelay sensor kinase activity
CNO08_RS22000	COG3279	Response regulator of the LytR AlgR family
CNO08_RS22060	COG2211	Major facilitator Superfamily
CNO08_RS22065	COG0673	inositol 2-dehydrogenase activity
CNO08_RS22075	COG2010	Cytochrome c
CNO08_RS22100	COG1472	Belongs to the glycosyl hydrolase 3 family
CNO08_RS22105	COG4771	TonB-dependent receptor
CNO08_RS22185	COG3537	Alpha-1,2-mannosidase
CNO08_RS22200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CNO08_RS22210	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CNO08_RS22230	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CNO08_RS22235	COG1490	D-aminoacyl-tRNA deacylase activity
CNO08_RS22265	COG3307	-O-antigen
CNO08_RS22275	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CNO08_RS22275	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CNO08_RS22280	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CNO08_RS22285	COG0242	peptide deformylase activity
CNO08_RS22290	COG1652	LysM domain
CNO08_RS22295	COG0758	DNA mediated transformation
CNO08_RS22300	COG2922	Belongs to the Smg family
CNO08_RS22310	COG1714	RDD family
CNO08_RS22370	COG0616	signal peptide processing
CNO08_RS22375	COG0534	Mate efflux family protein
CNO08_RS22405	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CNO08_RS22425	COG1252	NADH dehydrogenase
CNO08_RS22445	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
CNO08_RS22460	COG2264	protein methyltransferase activity
CNO08_RS22480	COG0572	uridine kinase
CNO08_RS22490	COG0463	Glycosyl transferase, family 2
CNO08_RS22505	COG3347	Dehydrogenase
CNO08_RS22505	COG1028	Short-chain dehydrogenase reductase Sdr
CNO08_RS22535	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CNO08_RS22555	COG0625	glutathione transferase activity
CNO08_RS22560	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CNO08_RS22595	COG0745	RESPONSE REGULATOR receiver
CNO08_RS22600	COG2205	protein histidine kinase activity
CNO08_RS22615	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CNO08_RS22640	COG0745	RESPONSE REGULATOR receiver
CNO08_RS22670	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CNO08_RS22675	COG0583	DNA-binding transcription factor activity
CNO08_RS22685	COG0583	DNA-binding transcription factor activity
CNO08_RS22710	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CNO08_RS22715	COG2201	protein-glutamate methylesterase activity
CNO08_RS22720	COG2177	Part of the ABC transporter FtsEX involved in
CNO08_RS22725	COG2884	Cell division ATP-binding protein ftsE
CNO08_RS22745	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CNO08_RS22775	COG3100	YcgL domain-containing protein
CNO08_RS22780	COG1294	oxidase, subunit
CNO08_RS22785	COG1271	oxidase subunit
CNO08_RS22795	COG0408	coproporphyrinogen oxidase activity
CNO08_RS22825	COG0823	Involved in the tonB-independent uptake of proteins
CNO08_RS22825	COG1506	peptidase
CNO08_RS22825	COG4946	Tricorn protease homolog
CNO08_RS22845	COG0210	DNA helicase
CNO08_RS22860	COG0625	glutathione transferase activity
CNO08_RS22875	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CNO08_RS22905	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CNO08_RS22915	COG0463	Glycosyl transferase, family 2
CNO08_RS22930	COG1028	Short-chain dehydrogenase reductase Sdr
CNO08_RS22960	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CNO08_RS22970	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CNO08_RS23015	COG1959	2 iron, 2 sulfur cluster binding
CNO08_RS23030	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CNO08_RS23045	COG3209	COG3209 Rhs family protein
CNO08_RS23060	COG4208	sulfate ABC transporter
CNO08_RS23115	COG0714	Associated with various cellular activities
CNO08_RS23145	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CNO08_RS23185	COG0357	Ribosomal RNA small subunit methyltransferase G
CNO08_RS23190	COG1192	Involved in chromosome partitioning
CNO08_RS23195	COG1475	DNA binding
CNO08_RS23210	COG0463	Glycosyl transferase, family 2
CNO08_RS23225	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CNO08_RS23230	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CNO08_RS23245	COG5002	protein histidine kinase activity
CNO08_RS23270	COG2852	Protein conserved in bacteria
CNO08_RS23285	COG0477	Major facilitator Superfamily
CNO08_RS23290	COG1573	uracil-dna glycosylase
CNO08_RS23295	COG2860	membrane
CNO08_RS23300	COG1131	(ABC) transporter
CNO08_RS23325	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CNO08_RS23335	COG0515	serine threonine protein kinase
CNO08_RS23335	COG2815	serine threonine protein kinase
CNO08_RS23350	COG2911	Protein conserved in bacteria
CNO08_RS23355	COG0729	surface antigen
CNO08_RS23375	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CNO08_RS23375	COG0519	Catalyzes the synthesis of GMP from XMP
CNO08_RS23385	COG1714	RDD family
CNO08_RS23390	COG0805	protein transport
CNO08_RS23395	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CNO08_RS23410	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CNO08_RS23415	COG0596	Alpha beta hydrolase
CNO08_RS23430	COG0037	tRNA processing
CNO08_RS23465	COG2937	Belongs to the GPAT DAPAT family
CNO08_RS23500	COG1917	Cupin 2, conserved barrel domain protein
CNO08_RS23500	COG4977	sequence-specific DNA binding
CNO08_RS23505	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
CNO08_RS23520	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CNO08_RS23540	COG0210	DNA helicase
CNO08_RS23555	COG3541	Predicted nucleotidyltransferase
CNO08_RS23565	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
CNO08_RS23575	COG0443	Heat shock 70 kDa protein
CNO08_RS23585	COG1111	helicase
CNO08_RS23585	COG1205	dead DEAH box helicase
CNO08_RS23630	COG0067	glutamate synthase
CNO08_RS23630	COG0069	glutamate synthase activity
CNO08_RS23630	COG0070	glutamate synthase
CNO08_RS23650	COG2199	diguanylate cyclase activity
CNO08_RS23705	COG0067	glutamate synthase
CNO08_RS23705	COG0070	glutamate synthase
CNO08_RS23705	COG0069	glutamate synthase activity
CNO08_RS23710	COG0493	'glutamate synthase
CNO08_RS23715	COG0302	gtp cyclohydrolase
CNO08_RS23725	COG3706	GGDEF domain
CNO08_RS23730	COG0697	spore germination
CNO08_RS23740	COG2267	carboxylic ester hydrolase activity
CNO08_RS23750	COG0156	8-amino-7-oxononanoate synthase activity
CNO08_RS23755	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CNO08_RS23780	COG2031	fatty acid transporter
CNO08_RS23795	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CNO08_RS23845	COG1573	uracil-dna glycosylase
CNO08_RS23870	COG1028	Short-chain dehydrogenase reductase Sdr
CNO08_RS23875	COG0583	DNA-binding transcription factor activity
CNO08_RS23910	COG1028	Short-chain dehydrogenase reductase Sdr
CNO08_RS23915	COG2207	Transcriptional regulator
CNO08_RS23915	COG0662	Cupin 2, conserved barrel domain protein
CNO08_RS23935	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CNO08_RS23970	COG0583	DNA-binding transcription factor activity
CNO08_RS23985	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CNO08_RS23995	COG1024	Enoyl-CoA hydratase
CNO08_RS24015	COG0583	DNA-binding transcription factor activity
CNO08_RS24025	COG1028	Short-chain dehydrogenase reductase Sdr
CNO08_RS24045	COG2207	Transcriptional regulator
CNO08_RS24050	COG0667	Aldo Keto reductase
CNO08_RS24055	COG1028	Short-chain dehydrogenase reductase Sdr
CNO08_RS24060	COG2067	long-chain fatty acid transport protein
CNO08_RS24090	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CNO08_RS24250	COG1695	Transcriptional regulator
CNO08_RS24335	COG2226	methyltransferase
CNO08_RS24340	COG1733	regulation of RNA biosynthetic process
CNO08_RS24345	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CNO08_RS24430	COG0745	RESPONSE REGULATOR receiver
CNO08_RS24435	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
CNO08_RS24440	COG0784	Response regulator, receiver
CNO08_RS24440	COG4191	Histidine kinase
CNO08_RS24455	COG3279	Response regulator of the LytR AlgR family
CNO08_RS24460	COG3275	phosphorelay sensor kinase activity
CNO08_RS24475	COG1660	Displays ATPase and GTPase activities
CNO08_RS24480	COG0625	glutathione transferase activity
CNO08_RS24505	COG0454	-acetyltransferase
CNO08_RS24525	COG0583	DNA-binding transcription factor activity
CNO08_RS24535	COG0583	DNA-binding transcription factor activity
CNO08_RS24565	COG0583	DNA-binding transcription factor activity
CNO08_RS24575	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CNO08_RS24585	COG0798	PFAM Bile acid sodium symporter
CNO08_RS24595	COG0431	NADPH-dependent FMN reductase
CNO08_RS24705	COG2871	sodium ion transport
CNO08_RS24770	COG0753	catalase activity
CNO08_RS24805	COG1741	Belongs to the pirin family
CNO08_RS24810	COG0583	DNA-binding transcription factor activity
CNO08_RS24815	COG0488	(ABC) transporter
CNO08_RS24845	COG3220	belongs to the UPF0276 family
CNO08_RS24855	COG2259	Doxx family
CNO08_RS24860	COG2223	nitrite transmembrane transporter activity
CNO08_RS24865	COG4771	TonB-dependent receptor
CNO08_RS24885	COG0583	DNA-binding transcription factor activity
CNO08_RS24895	COG2234	aminopeptidase activity
CNO08_RS24930	COG3275	phosphorelay sensor kinase activity
CNO08_RS24935	COG3279	Response regulator of the LytR AlgR family
CNO08_RS24980	COG0754	glutathionylspermidine amidase activity
CNO08_RS25005	COG1842	Phage shock protein A
CNO08_RS25035	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CNO08_RS25085	COG0531	amino acid
CNO08_RS25095	COG0667	Aldo Keto reductase
CNO08_RS25125	COG1473	amidohydrolase
CNO08_RS25145	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CNO08_RS25145	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CNO08_RS25150	COG1652	LysM domain
CNO08_RS25160	COG3012	SEC-C Motif Domain Protein
CNO08_RS25165	COG3318	Belongs to the UPF0149 family
CNO08_RS25165	COG3012	SEC-C Motif Domain Protein
CNO08_RS25170	COG0727	PFAM Uncharacterised protein family (UPF0153)
CNO08_RS25195	COG0538	isocitrate dehydrogenase activity
CNO08_RS25215	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
CNO08_RS25230	COG0583	DNA-binding transcription factor activity
CNO08_RS25245	COG1187	pseudouridine synthase activity
CNO08_RS25255	COG5444	nuclease activity
CNO08_RS25280	COG0667	Aldo Keto reductase
CNO08_RS25300	COG1643	Atp-dependent helicase
CNO08_RS25310	COG0084	hydrolase, TatD family'
CNO08_RS25335	COG0842	Transport permease protein
CNO08_RS25340	COG1131	(ABC) transporter
CNO08_RS25355	COG4555	ABC transporter
CNO08_RS25360	COG1668	transmembrane transport
CNO08_RS25375	COG4260	virion core protein, lumpy skin disease virus
CNO08_RS25385	COG2814	Major facilitator Superfamily
CNO08_RS25395	COG1902	pentaerythritol trinitrate reductase activity
CNO08_RS25420	COG0706	membrane insertase activity