locus-tag	class	description
FKV23_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FKV23_RS00020	COG0187	DNA topoisomerase II activity
FKV23_RS00075	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FKV23_RS00085	COG2205	protein histidine kinase activity
FKV23_RS00090	COG0784	Response regulator, receiver
FKV23_RS00115	COG2972	Histidine kinase
FKV23_RS00135	COG2197	response regulator
FKV23_RS00140	COG4585	Histidine kinase
FKV23_RS00200	COG4771	TonB-dependent receptor
FKV23_RS00235	COG3186	Phenylalanine-4-hydroxylase
FKV23_RS00260	COG1752	Esterase of the alpha-beta hydrolase superfamily
FKV23_RS00280	COG1125	glycine betaine transport
FKV23_RS00280	COG0517	IMP dehydrogenase activity
FKV23_RS00310	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FKV23_RS00320	COG2249	NAD(P)H dehydrogenase (quinone) activity
FKV23_RS00360	COG2853	Lipoprotein
FKV23_RS00375	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FKV23_RS00380	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FKV23_RS00385	COG1127	ABC transporter
FKV23_RS00400	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FKV23_RS00425	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FKV23_RS00460	COG0583	DNA-binding transcription factor activity
FKV23_RS00475	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
FKV23_RS00495	COG1074	ATP-dependent DNA helicase activity
FKV23_RS00500	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FKV23_RS00510	COG2223	nitrite transmembrane transporter activity
FKV23_RS00520	COG0243	molybdopterin cofactor binding
FKV23_RS00535	COG0583	DNA-binding transcription factor activity
FKV23_RS00545	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FKV23_RS00575	COG0302	gtp cyclohydrolase
FKV23_RS00585	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FKV23_RS00590	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
FKV23_RS00600	COG0493	'glutamate synthase
FKV23_RS00605	COG0069	glutamate synthase activity
FKV23_RS00605	COG0070	glutamate synthase
FKV23_RS00605	COG0067	glutamate synthase
FKV23_RS00640	COG1111	helicase
FKV23_RS00640	COG1205	dead DEAH box helicase
FKV23_RS00655	COG1595	DNA-templated transcription, initiation
FKV23_RS00705	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FKV23_RS00715	COG1404	Belongs to the peptidase S8 family
FKV23_RS00725	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FKV23_RS00725	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FKV23_RS00730	COG1652	LysM domain
FKV23_RS00740	COG0653	protein targeting
FKV23_RS00775	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FKV23_RS00785	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FKV23_RS00820	COG1842	Phage shock protein A
FKV23_RS00835	COG2255	four-way junction helicase activity
FKV23_RS00845	COG0596	Alpha beta hydrolase
FKV23_RS00850	COG0727	PFAM Uncharacterised protein family (UPF0153)
FKV23_RS00855	COG0318	PFAM AMP-dependent synthetase and ligase
FKV23_RS00860	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FKV23_RS00880	COG0564	pseudouridine synthase activity
FKV23_RS00895	COG4682	membrane
FKV23_RS00900	COG0606	chelatase, subunit chli
FKV23_RS00910	COG0347	Belongs to the P(II) protein family
FKV23_RS00920	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FKV23_RS00925	COG1166	arginine decarboxylase activity
FKV23_RS00935	COG2084	Dehydrogenase
FKV23_RS00950	COG0018	arginyl-trna synthetase
FKV23_RS00970	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FKV23_RS00980	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FKV23_RS00985	COG0708	Exodeoxyribonuclease III
FKV23_RS00990	COG2223	nitrite transmembrane transporter activity
FKV23_RS01000	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FKV23_RS01005	COG0739	heme binding
FKV23_RS01010	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FKV23_RS01045	COG0583	DNA-binding transcription factor activity
FKV23_RS01065	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FKV23_RS01070	COG4942	peptidase
FKV23_RS01075	COG0793	Belongs to the peptidase S41A family
FKV23_RS01090	COG2067	long-chain fatty acid transport protein
FKV23_RS01115	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
FKV23_RS01145	COG0109	protoheme IX farnesyltransferase activity
FKV23_RS01150	COG0392	lysyltransferase activity
FKV23_RS01155	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FKV23_RS01160	COG3568	Endonuclease Exonuclease Phosphatase
FKV23_RS01165	COG4946	Tricorn protease homolog
FKV23_RS01165	COG1506	peptidase
FKV23_RS01165	COG0823	Involved in the tonB-independent uptake of proteins
FKV23_RS01195	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FKV23_RS01200	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FKV23_RS01205	COG0668	transmembrane transport
FKV23_RS01210	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FKV23_RS01220	COG1028	Short-chain dehydrogenase reductase Sdr
FKV23_RS01235	COG4206	TonB-dependent receptor
FKV23_RS01240	COG0617	tRNA 3'-terminal CCA addition
FKV23_RS01245	COG3209	COG3209 Rhs family protein
FKV23_RS01270	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FKV23_RS01275	COG0741	lytic transglycosylase activity
FKV23_RS01285	COG0730	response to heat
FKV23_RS01300	COG1028	Short-chain dehydrogenase reductase Sdr
FKV23_RS01320	COG0477	Major facilitator Superfamily
FKV23_RS01340	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FKV23_RS01360	COG2272	Belongs to the type-B carboxylesterase lipase family
FKV23_RS01365	COG2755	lipolytic protein G-D-S-L family
FKV23_RS01415	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FKV23_RS01430	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FKV23_RS01440	COG0542	response to heat
FKV23_RS01450	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
FKV23_RS01450	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
FKV23_RS01460	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FKV23_RS01470	COG0583	DNA-binding transcription factor activity
FKV23_RS01480	COG1942	4-Oxalocrotonate Tautomerase
FKV23_RS01505	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FKV23_RS01530	COG4946	Tricorn protease homolog
FKV23_RS01530	COG1506	peptidase
FKV23_RS01530	COG0823	Involved in the tonB-independent uptake of proteins
FKV23_RS01535	COG1307	EDD domain protein, DegV family
FKV23_RS01545	COG0402	S-adenosylhomocysteine deaminase activity
FKV23_RS01550	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FKV23_RS01570	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FKV23_RS01595	COG0436	Aminotransferase
FKV23_RS01600	COG1162	GTPase activity
FKV23_RS01610	COG2020	methyltransferase activity
FKV23_RS01615	COG0745	RESPONSE REGULATOR receiver
FKV23_RS01620	COG0281	malic enzyme
FKV23_RS01620	COG0280	phosphate acetyltransferase
FKV23_RS01725	COG0686	Belongs to the AlaDH PNT family
FKV23_RS01730	COG1522	sequence-specific DNA binding
FKV23_RS01755	COG2814	Major facilitator Superfamily
FKV23_RS01785	COG1131	(ABC) transporter
FKV23_RS01790	COG0842	Transport permease protein
FKV23_RS01830	COG1690	Belongs to the RtcB family
FKV23_RS01890	COG4181	ATPase activity
FKV23_RS01895	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FKV23_RS01925	COG2813	Specifically methylates the guanine in position
FKV23_RS01930	COG1187	pseudouridine synthase activity
FKV23_RS01935	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FKV23_RS01945	COG1666	GTP binding
FKV23_RS01950	COG1064	alcohol dehydrogenase
FKV23_RS01955	COG0697	spore germination
FKV23_RS01970	COG0508	dehydrogenase complex catalyzes the overall conversion of
FKV23_RS01980	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FKV23_RS01980	COG3264	Mechanosensitive ion channel
FKV23_RS01985	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FKV23_RS02000	COG0356	it plays a direct role in the translocation of protons across the membrane
FKV23_RS02010	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FKV23_RS02015	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FKV23_RS02020	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FKV23_RS02030	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FKV23_RS02035	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FKV23_RS02055	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FKV23_RS02070	COG0515	serine threonine protein kinase
FKV23_RS02075	COG1132	(ABC) transporter
FKV23_RS02090	COG0577	efflux transmembrane transporter activity
FKV23_RS02095	COG0577	efflux transmembrane transporter activity
FKV23_RS02100	COG1136	(ABC) transporter
FKV23_RS02110	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FKV23_RS02130	COG4191	Histidine kinase
FKV23_RS02130	COG0784	Response regulator, receiver
FKV23_RS02155	COG4206	TonB-dependent receptor
FKV23_RS02165	COG1956	GAF domain-containing protein
FKV23_RS02175	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FKV23_RS02180	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FKV23_RS02195	COG0720	synthase
FKV23_RS02205	COG1051	belongs to the nudix hydrolase family
FKV23_RS02240	COG0316	Belongs to the HesB IscA family
FKV23_RS02250	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
FKV23_RS02290	COG0151	Belongs to the GarS family
FKV23_RS02295	COG1115	amino acid carrier protein
FKV23_RS02305	COG0138	bifunctional purine biosynthesis protein purh
FKV23_RS02310	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FKV23_RS02320	COG2264	protein methyltransferase activity
FKV23_RS02325	COG0439	Biotin carboxylase
FKV23_RS02330	COG0511	ligase activity, forming carbon-carbon bonds
FKV23_RS02340	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FKV23_RS02345	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FKV23_RS02355	COG1324	tolerance protein
FKV23_RS02360	COG2356	endonuclease I
FKV23_RS02390	COG0579	oxidoreductase
FKV23_RS02425	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FKV23_RS02430	COG1280	lysine exporter protein (LysE YggA)
FKV23_RS02440	COG0778	Nitroreductase
FKV23_RS02450	COG1741	Belongs to the pirin family
FKV23_RS02470	COG1560	Kdo2-lipid A biosynthetic process
FKV23_RS02475	COG1519	Transferase
FKV23_RS02480	COG1538	Outer membrane efflux protein
FKV23_RS02485	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FKV23_RS02490	COG1309	transcriptional regulator
FKV23_RS02510	COG1725	Transcriptional regulator
FKV23_RS02515	COG1131	(ABC) transporter
FKV23_RS02555	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FKV23_RS02585	COG0129	dihydroxy-acid dehydratase activity
FKV23_RS02600	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FKV23_RS02610	COG0460	homoserine dehydrogenase
FKV23_RS02610	COG0527	aspartate kinase activity
FKV23_RS02615	COG2234	aminopeptidase activity
FKV23_RS02620	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FKV23_RS02625	COG3710	Transcriptional regulator
FKV23_RS02625	COG0457	Tetratricopeptide repeat
FKV23_RS02640	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FKV23_RS02645	COG0668	transmembrane transport
FKV23_RS02650	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
FKV23_RS02675	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FKV23_RS02685	COG0586	Pfam SNARE associated Golgi protein
FKV23_RS02700	COG0346	lactoylglutathione lyase activity
FKV23_RS02705	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FKV23_RS02710	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FKV23_RS02715	COG0352	thiamine-phosphate diphosphorylase activity
FKV23_RS02720	COG1773	rubredoxin
FKV23_RS02755	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FKV23_RS02765	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FKV23_RS02795	COG0006	proline dipeptidase activity
FKV23_RS02800	COG0006	proline dipeptidase activity
FKV23_RS02805	COG5001	Diguanylate cyclase
FKV23_RS02805	COG5002	protein histidine kinase activity
FKV23_RS02820	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FKV23_RS02830	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FKV23_RS02835	COG1561	YicC-like family, N-terminal region
FKV23_RS02840	COG0194	GDP metabolic process
FKV23_RS02850	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FKV23_RS02860	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FKV23_RS02865	COG1446	asparaginase
FKV23_RS02870	COG3142	Participates in the control of copper homeostasis
FKV23_RS02875	COG3250	beta-galactosidase activity
FKV23_RS02890	COG3537	Alpha-1,2-mannosidase
FKV23_RS02905	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FKV23_RS02930	COG0254	rRNA binding
FKV23_RS02960	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FKV23_RS02990	COG0714	Associated with various cellular activities
FKV23_RS03020	COG1301	dicarboxylic acid transport
FKV23_RS03030	COG1136	(ABC) transporter
FKV23_RS03050	COG1136	(ABC) transporter
FKV23_RS03050	COG0577	efflux transmembrane transporter activity
FKV23_RS03055	COG0427	acetyl-CoA hydrolase
FKV23_RS03070	COG0730	response to heat
FKV23_RS03080	COG0640	Transcriptional regulator
FKV23_RS03085	COG0446	pyridine nucleotide-disulphide oxidoreductase
FKV23_RS03105	COG3118	belongs to the thioredoxin family
FKV23_RS03120	COG1294	oxidase, subunit
FKV23_RS03140	COG3047	cAMP biosynthetic process
FKV23_RS03145	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FKV23_RS03150	COG5001	Diguanylate cyclase
FKV23_RS03150	COG4251	negative regulation of phosphorylation
FKV23_RS03150	COG2203	Gaf domain
FKV23_RS03150	COG3706	GGDEF domain
FKV23_RS03155	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FKV23_RS03175	COG0126	phosphoglycerate kinase activity
FKV23_RS03190	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FKV23_RS03195	COG2031	fatty acid transporter
FKV23_RS03200	COG0469	pyruvate kinase activity
FKV23_RS03205	COG3588	fructose-bisphosphate aldolase
FKV23_RS03220	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FKV23_RS03230	COG0243	molybdopterin cofactor binding
FKV23_RS03240	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FKV23_RS03245	COG0454	-acetyltransferase
FKV23_RS03250	COG2223	nitrite transmembrane transporter activity
FKV23_RS03255	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FKV23_RS03255	COG1116	anion transmembrane transporter activity
FKV23_RS03265	COG1648	precorrin-2 dehydrogenase activity
FKV23_RS03265	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FKV23_RS03270	COG1115	amino acid carrier protein
FKV23_RS03275	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FKV23_RS03315	COG0523	cobalamin synthesis protein
FKV23_RS03335	COG3273	potassium ion transport
FKV23_RS03335	COG0471	metal ion transport
FKV23_RS03345	COG2022	thiamine diphosphate biosynthetic process
FKV23_RS03365	COG4067	protein conserved in archaea
FKV23_RS03365	COG0189	ligase activity
FKV23_RS03370	COG0189	ligase activity
FKV23_RS03375	COG0745	RESPONSE REGULATOR receiver
FKV23_RS03380	COG2205	protein histidine kinase activity
FKV23_RS03385	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FKV23_RS03395	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FKV23_RS03410	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FKV23_RS03425	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FKV23_RS03435	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FKV23_RS03440	COG2815	serine threonine protein kinase
FKV23_RS03440	COG0515	serine threonine protein kinase
FKV23_RS03455	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FKV23_RS03475	COG4106	trans-aconitate 2-methyltransferase activity
FKV23_RS03480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FKV23_RS03495	COG3422	double-strand break repair
FKV23_RS03505	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FKV23_RS03515	COG2119	membrane
FKV23_RS03520	COG0667	Aldo Keto reductase
FKV23_RS03530	COG4771	TonB-dependent receptor
FKV23_RS03540	COG0750	zinc metalloprotease
FKV23_RS03560	COG0330	HflC and HflK could
FKV23_RS03570	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FKV23_RS03575	COG0509	glycine decarboxylation via glycine cleavage system
FKV23_RS03590	COG1704	LemA family
FKV23_RS03595	COG0501	Belongs to the peptidase M48B family
FKV23_RS03615	COG1960	acyl-CoA dehydrogenase activity
FKV23_RS03620	COG1309	transcriptional regulator
FKV23_RS03625	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
FKV23_RS03640	COG2226	methyltransferase
FKV23_RS03660	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FKV23_RS03670	COG0463	Glycosyl transferase, family 2
FKV23_RS03680	COG1272	protein, Hemolysin III
FKV23_RS03690	COG0739	heme binding
FKV23_RS03700	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FKV23_RS03705	COG0626	cystathionine gamma-synthase activity
FKV23_RS03710	COG0460	homoserine dehydrogenase
FKV23_RS03710	COG0527	aspartate kinase activity
FKV23_RS03730	COG1760	l-serine dehydratase
FKV23_RS03755	COG0784	Response regulator, receiver
FKV23_RS03755	COG2198	Histidine kinase
FKV23_RS03755	COG2205	protein histidine kinase activity
FKV23_RS03785	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FKV23_RS03800	COG0259	pyridoxamine-phosphate oxidase activity
FKV23_RS03805	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FKV23_RS03845	COG1678	Uncharacterized ACR, COG1678
FKV23_RS03850	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FKV23_RS03855	COG0540	Belongs to the ATCase OTCase family
FKV23_RS03865	COG2239	Acts as a magnesium transporter
FKV23_RS03870	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FKV23_RS03895	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FKV23_RS03910	COG1137	ATPase activity
FKV23_RS03925	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FKV23_RS03935	COG0271	Belongs to the BolA IbaG family
FKV23_RS03955	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FKV23_RS03970	COG0628	permease
FKV23_RS03990	COG1595	DNA-templated transcription, initiation
FKV23_RS03995	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FKV23_RS04005	COG3178	'Phosphotransferase
FKV23_RS04015	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FKV23_RS04015	COG1648	precorrin-2 dehydrogenase activity
FKV23_RS04025	COG0583	DNA-binding transcription factor activity
FKV23_RS04030	COG2249	NAD(P)H dehydrogenase (quinone) activity
FKV23_RS04040	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FKV23_RS04045	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FKV23_RS04065	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FKV23_RS04090	COG4771	TonB-dependent receptor
FKV23_RS04105	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FKV23_RS04110	COG0719	Fe-S assembly protein
FKV23_RS04115	COG0396	ATPase activity
FKV23_RS04120	COG0719	Fe-S assembly protein
FKV23_RS04125	COG1959	2 iron, 2 sulfur cluster binding
FKV23_RS04135	COG1028	Short-chain dehydrogenase reductase Sdr
FKV23_RS04155	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FKV23_RS04175	COG1764	response to oxidative stress
FKV23_RS04195	COG0384	phenazine biosynthesis protein PhzF
FKV23_RS04200	COG0527	aspartate kinase activity
FKV23_RS04220	COG0142	geranyltranstransferase activity
FKV23_RS04225	COG0629	single-stranded DNA binding
FKV23_RS04255	COG1506	peptidase
FKV23_RS04255	COG0823	Involved in the tonB-independent uptake of proteins
FKV23_RS04265	COG1966	Carbon starvation protein
FKV23_RS04275	COG0003	Pfam Anion-transporting ATPase
FKV23_RS04295	COG4535	Mg2 and Co2 transporter CorC
FKV23_RS04300	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FKV23_RS04305	COG1702	phosphate starvation-inducible protein PhoH
FKV23_RS04320	COG1131	(ABC) transporter
FKV23_RS04325	COG0842	Transport permease protein
FKV23_RS04330	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FKV23_RS04335	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FKV23_RS04350	COG0741	lytic transglycosylase activity
FKV23_RS04355	COG0723	plastoquinol--plastocyanin reductase activity
FKV23_RS04360	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FKV23_RS04365	COG2857	Cytochrome c1
FKV23_RS04370	COG0625	glutathione transferase activity
FKV23_RS04375	COG2969	positive regulation of protein catabolic process
FKV23_RS04390	COG2835	tetraacyldisaccharide 4'-kinase activity
FKV23_RS04410	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FKV23_RS04415	COG1028	Short-chain dehydrogenase reductase Sdr
FKV23_RS04420	COG2095	MarC family integral membrane protein
FKV23_RS04430	COG1611	Belongs to the LOG family
FKV23_RS04435	COG3275	phosphorelay sensor kinase activity
FKV23_RS04505	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FKV23_RS04515	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FKV23_RS04520	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FKV23_RS04525	COG0072	phenylalanine-tRNA ligase activity
FKV23_RS04525	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FKV23_RS04570	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FKV23_RS04590	COG1960	acyl-CoA dehydrogenase activity
FKV23_RS04600	COG2197	response regulator
FKV23_RS04610	COG2815	serine threonine protein kinase
FKV23_RS04610	COG0515	serine threonine protein kinase
FKV23_RS04645	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
FKV23_RS04655	COG0552	protein localization to endoplasmic reticulum
FKV23_RS04660	COG0742	ribosomal rna small subunit methyltransferase
FKV23_RS04675	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FKV23_RS04685	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FKV23_RS04700	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FKV23_RS04715	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FKV23_RS04720	COG4535	Mg2 and Co2 transporter CorC
FKV23_RS04725	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FKV23_RS04740	COG1840	ABC-type Fe3 transport system, periplasmic component
FKV23_RS04750	COG3842	ATPase activity
FKV23_RS04760	COG1862	Preprotein translocase
FKV23_RS04765	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FKV23_RS04790	COG3300	MHYT domain
FKV23_RS04790	COG5001	Diguanylate cyclase
FKV23_RS04800	COG1253	flavin adenine dinucleotide binding
FKV23_RS04810	COG0306	phosphate transporter
FKV23_RS04835	COG3590	peptidase
FKV23_RS04840	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FKV23_RS04845	COG0513	Belongs to the DEAD box helicase family
FKV23_RS04850	COG5001	Diguanylate cyclase
FKV23_RS04850	COG2203	Gaf domain
FKV23_RS04850	COG4251	negative regulation of phosphorylation
FKV23_RS04850	COG3706	GGDEF domain
FKV23_RS04870	COG3275	phosphorelay sensor kinase activity
FKV23_RS04875	COG3279	Response regulator of the LytR AlgR family
FKV23_RS04885	COG0515	serine threonine protein kinase
FKV23_RS04885	COG2815	serine threonine protein kinase
FKV23_RS04910	COG1228	amidohydrolase
FKV23_RS04920	COG0495	leucyl-tRNA aminoacylation
FKV23_RS04925	COG0564	pseudouridine synthase activity
FKV23_RS04930	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FKV23_RS04945	COG0625	glutathione transferase activity
FKV23_RS04955	COG0446	pyridine nucleotide-disulphide oxidoreductase
FKV23_RS04955	COG1902	pentaerythritol trinitrate reductase activity
FKV23_RS04960	COG0604	alcohol dehydrogenase
FKV23_RS04975	COG2814	Major facilitator Superfamily
FKV23_RS04980	COG0583	DNA-binding transcription factor activity
FKV23_RS04985	COG2885	chlorophyll binding
FKV23_RS04985	COG3047	cAMP biosynthetic process
FKV23_RS04990	COG3047	cAMP biosynthetic process
FKV23_RS04990	COG2885	chlorophyll binding
FKV23_RS05000	COG1187	pseudouridine synthase activity
FKV23_RS05030	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FKV23_RS05035	COG0588	phosphoglycerate mutase activity
FKV23_RS05040	COG0285	dihydrofolate synthase activity
FKV23_RS05055	COG1286	toxin biosynthetic process
FKV23_RS05065	COG2833	Protein of unknown function (DUF455)
FKV23_RS05070	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FKV23_RS05080	COG0745	RESPONSE REGULATOR receiver
FKV23_RS05085	COG0642	Histidine kinase
FKV23_RS05095	COG0735	belongs to the Fur family
FKV23_RS05120	COG1228	amidohydrolase
FKV23_RS05130	COG2226	methyltransferase
FKV23_RS05145	COG2972	Histidine kinase
FKV23_RS05180	COG1309	transcriptional regulator
FKV23_RS05185	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FKV23_RS05195	COG0534	Mate efflux family protein
FKV23_RS05220	COG1187	pseudouridine synthase activity
FKV23_RS05240	COG4941	Belongs to the sigma-70 factor family
FKV23_RS05295	COG0583	DNA-binding transcription factor activity
FKV23_RS05345	COG1695	Transcriptional regulator
FKV23_RS05370	COG1981	membrane
FKV23_RS05380	COG1301	dicarboxylic acid transport
FKV23_RS05385	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FKV23_RS05390	COG1051	belongs to the nudix hydrolase family
FKV23_RS05405	COG1607	acyl-coa hydrolase
FKV23_RS05410	COG0791	NLP P60 protein
FKV23_RS05415	COG0791	NLP P60 protein
FKV23_RS05425	COG2311	Membrane
FKV23_RS05430	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FKV23_RS05460	COG0504	CTP synthase activity
FKV23_RS05465	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FKV23_RS05480	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FKV23_RS05480	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FKV23_RS05495	COG1193	negative regulation of DNA recombination
FKV23_RS05500	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FKV23_RS05510	COG1238	metal cluster binding
FKV23_RS05525	COG1534	Rna-binding protein
FKV23_RS05530	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FKV23_RS05540	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FKV23_RS05555	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FKV23_RS05560	COG1923	regulation of RNA biosynthetic process
FKV23_RS05565	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FKV23_RS05570	COG0330	HflC and HflK could
FKV23_RS05575	COG0330	HflC and HflK could
FKV23_RS05605	COG0477	Major facilitator Superfamily
FKV23_RS05615	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FKV23_RS05620	COG1028	Short-chain dehydrogenase reductase Sdr
FKV23_RS05630	COG4572	Cation transport regulator
FKV23_RS05640	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FKV23_RS05680	COG1999	signal sequence binding
FKV23_RS05685	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
FKV23_RS05710	COG2205	protein histidine kinase activity
FKV23_RS05750	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FKV23_RS05755	COG1120	ATPase activity
FKV23_RS05760	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FKV23_RS05760	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FKV23_RS05765	COG2814	Major facilitator Superfamily
FKV23_RS05775	COG2183	response to ionizing radiation
FKV23_RS05780	COG2226	methyltransferase
FKV23_RS05800	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FKV23_RS05810	COG0850	regulation of cytokinetic process
FKV23_RS05820	COG4585	Histidine kinase
FKV23_RS05825	COG2197	response regulator
FKV23_RS05840	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FKV23_RS05905	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FKV23_RS05915	COG1595	DNA-templated transcription, initiation
FKV23_RS05925	COG1946	Acyl-CoA thioesterase
FKV23_RS05945	COG0116	Belongs to the methyltransferase superfamily
FKV23_RS05945	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FKV23_RS05955	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FKV23_RS05965	COG1741	Belongs to the pirin family
FKV23_RS06015	COG0666	response to abiotic stimulus
FKV23_RS06090	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FKV23_RS06105	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FKV23_RS06110	COG0745	RESPONSE REGULATOR receiver
FKV23_RS06115	COG2205	protein histidine kinase activity
FKV23_RS06120	COG4452	Inner membrane protein CreD
FKV23_RS06135	COG1522	sequence-specific DNA binding
FKV23_RS06140	COG0626	cystathionine gamma-synthase activity
FKV23_RS06145	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FKV23_RS06175	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FKV23_RS06190	COG0589	response to stress
FKV23_RS06195	COG0659	secondary active sulfate transmembrane transporter activity
FKV23_RS06200	COG4771	TonB-dependent receptor
FKV23_RS06205	COG1546	Belongs to the CinA family
FKV23_RS06215	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FKV23_RS06220	COG2137	regulation of response to DNA damage stimulus
FKV23_RS06225	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FKV23_RS06230	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FKV23_RS06250	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FKV23_RS06295	COG1045	serine acetyltransferase
FKV23_RS06335	COG0438	transferase activity, transferring glycosyl groups
FKV23_RS06340	COG0438	transferase activity, transferring glycosyl groups
FKV23_RS06370	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FKV23_RS06375	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FKV23_RS06385	COG0351	phosphomethylpyrimidine kinase
FKV23_RS06390	COG0659	secondary active sulfate transmembrane transporter activity
FKV23_RS06405	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FKV23_RS06410	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FKV23_RS06420	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FKV23_RS06430	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FKV23_RS06440	COG0617	tRNA 3'-terminal CCA addition
FKV23_RS06445	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FKV23_RS06450	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FKV23_RS06455	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FKV23_RS06460	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FKV23_RS06475	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FKV23_RS06490	COG0860	N-Acetylmuramoyl-L-alanine amidase
FKV23_RS06495	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FKV23_RS06515	COG2878	Part of a membrane complex involved in electron transport
FKV23_RS06520	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FKV23_RS06520	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FKV23_RS06535	COG4771	TonB-dependent receptor
FKV23_RS06540	COG0489	protein tyrosine kinase activity
FKV23_RS06550	COG0717	Belongs to the dCTP deaminase family
FKV23_RS06565	COG1984	allophanate hydrolase subunit 2
FKV23_RS06570	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FKV23_RS06580	COG0412	Dienelactone hydrolase
FKV23_RS06595	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FKV23_RS06600	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FKV23_RS06605	COG0433	COG0433 Predicted ATPase
FKV23_RS06620	COG1999	signal sequence binding
FKV23_RS06625	COG2890	protein-(glutamine-N5) methyltransferase activity
FKV23_RS06630	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FKV23_RS06635	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FKV23_RS06645	COG0101	tRNA pseudouridine synthase activity
FKV23_RS06650	COG0135	phosphoribosylanthranilate isomerase activity
FKV23_RS06655	COG0133	tryptophan synthase activity
FKV23_RS06670	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FKV23_RS06690	COG0149	triose-phosphate isomerase activity
FKV23_RS06705	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FKV23_RS06715	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FKV23_RS06720	COG0649	NAD binding
FKV23_RS06725	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FKV23_RS06730	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FKV23_RS06740	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FKV23_RS06770	COG1007	ATP synthesis coupled electron transport
FKV23_RS06780	COG3278	Belongs to the heme-copper respiratory oxidase family
FKV23_RS06795	COG2010	Cytochrome c
FKV23_RS06815	COG2217	Heavy metal translocating P-type atpase
FKV23_RS06830	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FKV23_RS06835	COG0779	Required for maturation of 30S ribosomal subunits
FKV23_RS06840	COG0195	Participates in both transcription termination and antitermination
FKV23_RS06860	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FKV23_RS06865	COG1185	polyribonucleotide nucleotidyltransferase activity
FKV23_RS06890	COG0531	amino acid
FKV23_RS06900	COG1737	Transcriptional regulator
FKV23_RS06905	COG4948	Mandelate Racemase Muconate Lactonizing
FKV23_RS06935	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
FKV23_RS06940	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FKV23_RS06950	COG4772	TonB-dependent receptor
FKV23_RS06955	COG2610	gluconate transmembrane transporter activity
FKV23_RS06990	COG1183	phosphatidylcholine synthase activity
FKV23_RS07000	COG3243	poly(R)-hydroxyalkanoic acid synthase
FKV23_RS07005	COG1983	PspC domain protein
FKV23_RS07055	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FKV23_RS07075	COG4133	protoheme IX ABC transporter activity
FKV23_RS07085	COG3938	Belongs to the proline racemase family
FKV23_RS07105	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FKV23_RS07135	COG0436	Aminotransferase
FKV23_RS07175	COG0330	HflC and HflK could
FKV23_RS07195	COG1187	pseudouridine synthase activity
FKV23_RS07200	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FKV23_RS07210	COG2350	Protein conserved in bacteria
FKV23_RS07215	COG5007	Belongs to the BolA IbaG family
FKV23_RS07225	COG3115	cell septum assembly
FKV23_RS07230	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FKV23_RS07235	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FKV23_RS07245	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
FKV23_RS07255	COG2373	Large extracellular alpha-helical protein
FKV23_RS07260	COG4953	penicillin-binding protein 1C
FKV23_RS07265	COG0678	peroxiredoxin activity
FKV23_RS07355	COG0604	alcohol dehydrogenase
FKV23_RS07370	COG0508	dehydrogenase complex catalyzes the overall conversion of
FKV23_RS07375	COG0567	Dehydrogenase, E1 component
FKV23_RS07385	COG2850	peptidyl-arginine hydroxylation
FKV23_RS07420	COG1131	(ABC) transporter
FKV23_RS07425	COG1725	Transcriptional regulator
FKV23_RS07435	COG0386	Belongs to the glutathione peroxidase family
FKV23_RS07445	COG0545	Peptidyl-prolyl cis-trans isomerase
FKV23_RS07455	COG2900	Belongs to the SlyX family
FKV23_RS07480	COG1960	acyl-CoA dehydrogenase activity
FKV23_RS07485	COG2902	Dehydrogenase
FKV23_RS07490	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FKV23_RS07510	COG2925	Exonuclease
FKV23_RS07515	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FKV23_RS07520	COG3844	kynureninase activity
FKV23_RS07540	COG0288	reversible hydration of carbon dioxide
FKV23_RS07575	COG0316	Belongs to the HesB IscA family
FKV23_RS07585	COG0360	Binds together with S18 to 16S ribosomal RNA
FKV23_RS07590	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FKV23_RS07600	COG0305	Participates in initiation and elongation during chromosome replication
FKV23_RS07605	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FKV23_RS07615	COG2885	chlorophyll binding
FKV23_RS07620	COG1285	pathogenesis
FKV23_RS07630	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FKV23_RS07655	COG4251	negative regulation of phosphorylation
FKV23_RS07660	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FKV23_RS07675	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FKV23_RS07690	COG1420	regulation of RNA biosynthetic process
FKV23_RS07695	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FKV23_RS07700	COG0443	Heat shock 70 kDa protein
FKV23_RS07710	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FKV23_RS07720	COG0505	Belongs to the CarA family
FKV23_RS07725	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FKV23_RS07730	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FKV23_RS07760	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FKV23_RS07770	COG2198	Histidine kinase
FKV23_RS07770	COG2205	protein histidine kinase activity
FKV23_RS07770	COG0784	Response regulator, receiver
FKV23_RS07775	COG1024	Enoyl-CoA hydratase
FKV23_RS07780	COG0318	PFAM AMP-dependent synthetase and ligase
FKV23_RS07810	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FKV23_RS07830	COG0367	asparagine synthase
FKV23_RS07835	COG0318	PFAM AMP-dependent synthetase and ligase
FKV23_RS07845	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FKV23_RS07855	COG0482	sulfurtransferase activity
FKV23_RS07875	COG0542	response to heat
FKV23_RS07885	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FKV23_RS07895	COG0492	ferredoxin-NADP+ reductase activity
FKV23_RS07900	COG1674	ftsk spoiiie
FKV23_RS07915	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FKV23_RS07920	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FKV23_RS07930	COG4459	periplasmic nitrate reductase
FKV23_RS07940	COG3062	negative regulation of establishment of protein localization
FKV23_RS07945	COG0243	molybdopterin cofactor binding
FKV23_RS07950	COG3043	anaerobic respiration
FKV23_RS07955	COG3005	denitrification pathway
FKV23_RS07975	COG2217	Heavy metal translocating P-type atpase
FKV23_RS07990	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FKV23_RS08110	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FKV23_RS08120	COG0668	transmembrane transport
FKV23_RS08125	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FKV23_RS08140	COG3474	cytochrome
FKV23_RS08150	COG0519	Catalyzes the synthesis of GMP from XMP
FKV23_RS08150	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FKV23_RS08160	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FKV23_RS08185	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FKV23_RS08190	COG0303	'Molybdopterin
FKV23_RS08200	COG1160	GTP binding
FKV23_RS08205	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FKV23_RS08230	COG0105	UTP biosynthetic process
FKV23_RS08240	COG1024	Enoyl-CoA hydratase
FKV23_RS08240	COG1250	3-hydroxyacyl-CoA dehydrogenase
FKV23_RS08245	COG0183	Belongs to the thiolase family
FKV23_RS08250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FKV23_RS08280	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FKV23_RS08290	COG0776	regulation of translation
FKV23_RS08300	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FKV23_RS08315	COG2957	Belongs to the agmatine deiminase family
FKV23_RS08320	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FKV23_RS08345	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FKV23_RS08380	COG0316	Belongs to the HesB IscA family
FKV23_RS08380	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FKV23_RS08400	COG1530	ribonuclease E activity
FKV23_RS08415	COG2818	Glycosylase
FKV23_RS08425	COG0583	DNA-binding transcription factor activity
FKV23_RS08430	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FKV23_RS08440	COG0515	serine threonine protein kinase
FKV23_RS08460	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FKV23_RS08480	COG0077	Prephenate dehydratase
FKV23_RS08480	COG1605	Chorismate mutase
FKV23_RS08485	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FKV23_RS08490	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FKV23_RS08495	COG3227	Zinc metalloprotease (Elastase)
FKV23_RS08500	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FKV23_RS08545	COG1191	sigma factor activity
FKV23_RS08550	COG1338	Plays a role in the flagellum-specific transport system
FKV23_RS08565	COG1749	Flagellar hook protein flgE
FKV23_RS08570	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FKV23_RS08585	COG1157	protein secretion by the type III secretion system
FKV23_RS08615	COG1558	bacterial-type flagellum-dependent cell motility
FKV23_RS08625	COG1706	bacterial-type flagellum-dependent cell motility
FKV23_RS08640	COG4786	Flagellar basal body rod
FKV23_RS08650	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FKV23_RS08655	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FKV23_RS08760	COG0069	glutamate synthase activity
FKV23_RS08765	COG2951	lytic endotransglycosylase activity
FKV23_RS08790	COG0322	excinuclease ABC activity
FKV23_RS08795	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FKV23_RS08800	COG1663	tetraacyldisaccharide 4'-kinase activity
FKV23_RS08810	COG0848	biopolymer transport protein
FKV23_RS08815	COG0811	peptide transport
FKV23_RS08820	COG2333	competence protein COMEC
FKV23_RS08820	COG0658	competence protein
FKV23_RS08830	COG4591	ABC-type transport system involved in lipoprotein release permease component
FKV23_RS08850	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FKV23_RS08860	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FKV23_RS08905	COG0471	metal ion transport
FKV23_RS08920	COG1960	acyl-CoA dehydrogenase activity
FKV23_RS08935	COG0084	hydrolase, TatD family'
FKV23_RS08940	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FKV23_RS08955	COG1278	Cold shock
FKV23_RS08970	COG3621	Patatin-like phospholipase
FKV23_RS08975	COG0625	glutathione transferase activity
FKV23_RS08985	COG3275	phosphorelay sensor kinase activity
FKV23_RS08990	COG3279	Response regulator of the LytR AlgR family
FKV23_RS09010	COG2860	membrane
FKV23_RS09020	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FKV23_RS09045	COG0589	response to stress
FKV23_RS09050	COG0386	Belongs to the glutathione peroxidase family
FKV23_RS09055	COG4771	TonB-dependent receptor
FKV23_RS09060	COG0339	signal peptide processing
FKV23_RS09070	COG0584	glycerophosphoryl diester phosphodiesterase
FKV23_RS09075	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FKV23_RS09140	COG0488	(ABC) transporter
FKV23_RS09145	COG1404	Belongs to the peptidase S8 family
FKV23_RS09160	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FKV23_RS09175	COG0519	Catalyzes the synthesis of GMP from XMP
FKV23_RS09180	COG0564	pseudouridine synthase activity
FKV23_RS09190	COG2081	HI0933 family
FKV23_RS09210	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FKV23_RS09220	COG0583	DNA-binding transcription factor activity
FKV23_RS09230	COG0640	Transcriptional regulator
FKV23_RS09250	COG2207	Transcriptional regulator
FKV23_RS09255	COG0667	Aldo Keto reductase
FKV23_RS09270	COG0789	Transcriptional regulator
FKV23_RS09275	COG2814	Major facilitator Superfamily
FKV23_RS09280	COG0438	transferase activity, transferring glycosyl groups
FKV23_RS09285	COG0477	Major facilitator Superfamily
FKV23_RS09310	COG2824	Alkylphosphonate utilization operon protein PhnA
FKV23_RS09315	COG0673	inositol 2-dehydrogenase activity
FKV23_RS09365	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FKV23_RS09370	COG1846	Transcriptional regulator
FKV23_RS09375	COG1764	response to oxidative stress
FKV23_RS09385	COG2823	Periplasmic or secreted lipoprotein
FKV23_RS09420	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FKV23_RS09425	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FKV23_RS09440	COG1392	Phosphate transport regulator
FKV23_RS09445	COG0306	phosphate transporter
FKV23_RS09450	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FKV23_RS09475	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FKV23_RS09480	COG4232	protein-disulfide reductase activity
FKV23_RS09500	COG0500	methyltransferase
FKV23_RS09510	COG5507	3-demethylubiquinone-9 3-methyltransferase
FKV23_RS09525	COG2197	response regulator
FKV23_RS09570	COG3791	Glutathione-dependent formaldehyde-activating
FKV23_RS09575	COG0625	glutathione transferase activity
FKV23_RS09605	COG2311	Membrane
FKV23_RS09610	COG0402	S-adenosylhomocysteine deaminase activity
FKV23_RS09625	COG0435	Glutathione S-transferase
FKV23_RS09635	COG2267	carboxylic ester hydrolase activity
FKV23_RS09680	COG0513	Belongs to the DEAD box helicase family
FKV23_RS09695	COG1901	pseudouridine methyltransferase
FKV23_RS09720	COG2226	methyltransferase
FKV23_RS09725	COG3507	Belongs to the glycosyl hydrolase 43 family
FKV23_RS09740	COG3693	PFAM glycoside hydrolase, family 10
FKV23_RS09740	COG3509	depolymerase
FKV23_RS09750	COG2226	methyltransferase
FKV23_RS09830	COG1228	amidohydrolase
FKV23_RS09850	COG0583	DNA-binding transcription factor activity
FKV23_RS09860	COG1335	isochorismatase
FKV23_RS09880	COG2764	glyoxalase bleomycin resistance protein dioxygenase
FKV23_RS09895	COG0604	alcohol dehydrogenase
FKV23_RS09900	COG0604	alcohol dehydrogenase
FKV23_RS09905	COG2267	carboxylic ester hydrolase activity
FKV23_RS09910	COG0300	oxidoreductase activity
FKV23_RS09940	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FKV23_RS09940	COG1703	isobutyryl-CoA mutase activity
FKV23_RS09940	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FKV23_RS09950	COG1960	acyl-CoA dehydrogenase activity
FKV23_RS09960	COG0183	Belongs to the thiolase family
FKV23_RS09975	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FKV23_RS09990	COG0672	)-iron permease
FKV23_RS09995	COG1024	Enoyl-CoA hydratase
FKV23_RS10000	COG4770	biotin carboxylase activity
FKV23_RS10020	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FKV23_RS10030	COG1757	Na H antiporter
FKV23_RS10040	COG0235	Class ii aldolase
FKV23_RS10045	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
FKV23_RS10050	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
FKV23_RS10070	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FKV23_RS10075	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FKV23_RS10090	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FKV23_RS10105	COG3706	GGDEF domain
FKV23_RS10110	COG2986	histidine ammonia-lyase
FKV23_RS10135	COG0726	polysaccharide deacetylase
FKV23_RS10135	COG1649	PFAM Uncharacterised BCR, COG1649
FKV23_RS10140	COG1215	transferase activity, transferring glycosyl groups
FKV23_RS10160	COG0165	Argininosuccinate lyase
FKV23_RS10165	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FKV23_RS10170	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FKV23_RS10175	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FKV23_RS10180	COG0137	argininosuccinate synthase activity
FKV23_RS10185	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FKV23_RS10200	COG2166	iron-sulfur cluster assembly
FKV23_RS10215	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FKV23_RS10225	COG1469	GTP cyclohydrolase I activity
FKV23_RS10245	COG0402	S-adenosylhomocysteine deaminase activity
FKV23_RS10255	COG1509	lysine 2,3-aminomutase activity
FKV23_RS10260	COG3300	MHYT domain
FKV23_RS10260	COG5001	Diguanylate cyclase
FKV23_RS10275	COG1028	Short-chain dehydrogenase reductase Sdr
FKV23_RS10305	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FKV23_RS10335	COG1752	Esterase of the alpha-beta hydrolase superfamily
FKV23_RS10370	COG3119	arylsulfatase activity
FKV23_RS10390	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FKV23_RS10405	COG4566	intracellular signal transduction
FKV23_RS10415	COG4191	Histidine kinase
FKV23_RS10420	COG2982	Protein involved in outer membrane biogenesis
FKV23_RS10485	COG1404	Belongs to the peptidase S8 family
FKV23_RS10525	COG1012	belongs to the aldehyde dehydrogenase family
FKV23_RS10535	COG0167	dihydroorotate dehydrogenase activity
FKV23_RS10540	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FKV23_RS10545	COG0697	spore germination
FKV23_RS10580	COG0671	phosphoesterase, PA-phosphatase related
FKV23_RS10585	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FKV23_RS10605	COG1012	belongs to the aldehyde dehydrogenase family
FKV23_RS10610	COG3001	Fructosamine kinase
FKV23_RS10620	COG5001	Diguanylate cyclase
FKV23_RS10640	COG1132	(ABC) transporter
FKV23_RS10660	COG1960	acyl-CoA dehydrogenase activity
FKV23_RS10670	COG1278	Cold shock
FKV23_RS10675	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FKV23_RS10680	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
FKV23_RS10685	COG1472	Belongs to the glycosyl hydrolase 3 family
FKV23_RS10690	COG2954	triphosphatase activity
FKV23_RS10695	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FKV23_RS10705	COG1381	Involved in DNA repair and RecF pathway recombination
FKV23_RS10725	COG0681	Belongs to the peptidase S26 family
FKV23_RS10750	COG1024	Enoyl-CoA hydratase
FKV23_RS10750	COG1250	3-hydroxyacyl-CoA dehydrogenase
FKV23_RS10770	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FKV23_RS10775	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FKV23_RS10785	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FKV23_RS10800	COG1028	Short-chain dehydrogenase reductase Sdr
FKV23_RS10815	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FKV23_RS10820	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FKV23_RS10825	COG1399	metal-binding, possibly nucleic acid-binding protein
FKV23_RS10845	COG0714	Associated with various cellular activities
FKV23_RS10850	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
FKV23_RS10870	COG0537	adenosine 5'-monophosphoramidase activity
FKV23_RS10885	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FKV23_RS10905	COG0314	molybdopterin synthase activity
FKV23_RS10910	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FKV23_RS10915	COG0315	cyclic pyranopterin monophosphate synthase activity
FKV23_RS10930	COG3642	lipopolysaccharide core region biosynthetic process
FKV23_RS10935	COG0859	PFAM glycosyl transferase family 9
FKV23_RS10960	COG0631	protein serine/threonine phosphatase activity
FKV23_RS10995	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FKV23_RS11025	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FKV23_RS11030	COG0740	serine-type endopeptidase activity
FKV23_RS11035	COG0544	peptidyl-prolyl cis-trans isomerase activity
FKV23_RS11075	COG0473	3-isopropylmalate dehydrogenase activity
FKV23_RS11090	COG4783	chaperone-mediated protein folding
FKV23_RS11095	COG0745	RESPONSE REGULATOR receiver
FKV23_RS11105	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FKV23_RS11110	COG0248	Ppx GppA phosphatase
FKV23_RS11125	COG0438	transferase activity, transferring glycosyl groups
FKV23_RS11145	COG0336	Belongs to the RNA methyltransferase TrmD family
FKV23_RS11150	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FKV23_RS11155	COG0228	four-way junction DNA binding
FKV23_RS11165	COG3267	Type II secretory pathway component ExeA
FKV23_RS11165	COG3409	Peptidoglycan-binding domain 1 protein
FKV23_RS11170	COG1404	Belongs to the peptidase S8 family
FKV23_RS11175	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FKV23_RS11195	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FKV23_RS11205	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FKV23_RS11210	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FKV23_RS11220	COG0196	riboflavin kinase activity
FKV23_RS11230	COG0268	Binds directly to 16S ribosomal RNA
FKV23_RS11235	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FKV23_RS11240	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FKV23_RS11250	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FKV23_RS11260	COG0824	Thioesterase
FKV23_RS11290	COG1024	Enoyl-CoA hydratase
FKV23_RS11300	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FKV23_RS11320	COG0573	inorganic phosphate transmembrane transporter activity
FKV23_RS11325	COG0581	inorganic phosphate transmembrane transporter activity
FKV23_RS11335	COG0704	Plays a role in the regulation of phosphate uptake
FKV23_RS11345	COG3220	belongs to the UPF0276 family
FKV23_RS11355	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FKV23_RS11360	COG2076	Multidrug Resistance protein
FKV23_RS11365	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FKV23_RS11370	COG0557	exoribonuclease II activity
FKV23_RS11385	COG0500	methyltransferase
FKV23_RS11400	COG0367	asparagine synthase
FKV23_RS11410	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FKV23_RS11415	COG1393	Belongs to the ArsC family
FKV23_RS11430	COG0024	Methionine aminopeptidase
FKV23_RS11455	COG0052	Belongs to the universal ribosomal protein uS2 family
FKV23_RS11480	COG1595	DNA-templated transcription, initiation
FKV23_RS11500	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FKV23_RS11505	COG0575	Belongs to the CDS family
FKV23_RS11510	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FKV23_RS11515	COG0750	zinc metalloprotease
FKV23_RS11535	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FKV23_RS11540	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FKV23_RS11580	COG1722	exodeoxyribonuclease VII activity
FKV23_RS11585	COG0142	geranyltranstransferase activity
FKV23_RS11595	COG0312	modulator of DNA gyrase
FKV23_RS11605	COG0312	modulator of DNA gyrase
FKV23_RS11610	COG3164	Protein of unknown function
FKV23_RS11620	COG0424	maF-like protein
FKV23_RS11625	COG2968	Membrane
FKV23_RS11635	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FKV23_RS11645	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FKV23_RS11660	COG0039	L-malate dehydrogenase activity
FKV23_RS11675	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FKV23_RS11680	COG1217	gtp-binding protein TYPA
FKV23_RS11685	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FKV23_RS11690	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FKV23_RS11700	COG0202	RNA polymerase activity
FKV23_RS11705	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FKV23_RS11715	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FKV23_RS11720	COG0201	protein transport
FKV23_RS11725	COG0200	Binds to the 23S rRNA
FKV23_RS11730	COG1841	ribosomal large subunit assembly
FKV23_RS11740	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FKV23_RS11745	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FKV23_RS11755	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FKV23_RS11760	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FKV23_RS11765	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FKV23_RS11775	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FKV23_RS11780	COG0255	Belongs to the universal ribosomal protein uL29 family
FKV23_RS11785	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FKV23_RS11790	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FKV23_RS11805	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FKV23_RS11810	COG0089	rRNA binding
FKV23_RS11815	COG0088	Forms part of the polypeptide exit tunnel
FKV23_RS11820	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FKV23_RS11825	COG0051	transcription antitermination factor activity, RNA binding
FKV23_RS11830	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FKV23_RS11835	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FKV23_RS11840	COG0049	tRNA binding
FKV23_RS11850	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FKV23_RS11855	COG0085	RNA polymerase activity
FKV23_RS11860	COG0222	ribosome binding
FKV23_RS11865	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FKV23_RS11870	COG0081	regulation of translation
FKV23_RS11875	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FKV23_RS11880	COG0250	Participates in transcription elongation, termination and antitermination
FKV23_RS11885	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FKV23_RS11895	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FKV23_RS11920	COG0193	aminoacyl-tRNA hydrolase activity
FKV23_RS11930	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FKV23_RS11940	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FKV23_RS11960	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FKV23_RS11990	COG0596	Alpha beta hydrolase
FKV23_RS11995	COG0521	Mo-molybdopterin cofactor biosynthetic process
FKV23_RS12020	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FKV23_RS12025	COG1295	ribonuclease BN
FKV23_RS12055	COG4771	TonB-dependent receptor
FKV23_RS12060	COG1404	Belongs to the peptidase S8 family
FKV23_RS12075	COG2151	metal-sulfur cluster biosynthetic enzyme
FKV23_RS12085	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FKV23_RS12160	COG3634	alkyl hydroperoxide reductase activity
FKV23_RS12290	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FKV23_RS12320	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FKV23_RS12325	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FKV23_RS12335	COG2096	Adenosyltransferase
FKV23_RS12350	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FKV23_RS12355	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FKV23_RS12360	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FKV23_RS12365	COG2967	ApaG domain
FKV23_RS12370	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FKV23_RS12375	COG3738	Protein conserved in bacteria
FKV23_RS12400	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FKV23_RS12405	COG1446	asparaginase
FKV23_RS12410	COG1136	(ABC) transporter
FKV23_RS12410	COG0577	efflux transmembrane transporter activity
FKV23_RS12415	COG1136	(ABC) transporter
FKV23_RS12415	COG0577	efflux transmembrane transporter activity
FKV23_RS12420	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FKV23_RS12425	COG0642	Histidine kinase
FKV23_RS12430	COG0745	RESPONSE REGULATOR receiver
FKV23_RS12445	COG3956	TIGRFAM MazG family protein
FKV23_RS12455	COG0494	nUDIX hydrolase
FKV23_RS12465	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FKV23_RS12495	COG2198	Histidine kinase
FKV23_RS12495	COG2198	Histidine kinase
FKV23_RS12495	COG0784	Response regulator, receiver
FKV23_RS12495	COG0643	Histidine kinase
FKV23_RS12495	COG0643	Histidine kinase
FKV23_RS12495	COG0784	Response regulator, receiver
FKV23_RS12500	COG0840	transmembrane signaling receptor activity
FKV23_RS12520	COG0189	ligase activity
FKV23_RS12535	COG1199	ATP-dependent helicase activity
FKV23_RS12545	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FKV23_RS12550	COG1215	transferase activity, transferring glycosyl groups
FKV23_RS12560	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FKV23_RS12575	COG0783	Belongs to the Dps family
FKV23_RS12585	COG0514	ATP-dependent DNA helicase (RecQ)
FKV23_RS12605	COG2885	chlorophyll binding
FKV23_RS12625	COG0745	RESPONSE REGULATOR receiver
FKV23_RS12625	COG2205	protein histidine kinase activity
FKV23_RS12625	COG3292	Two component regulator propeller
FKV23_RS12630	COG0745	RESPONSE REGULATOR receiver
FKV23_RS12635	COG1595	DNA-templated transcription, initiation
FKV23_RS12950	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FKV23_RS12955	COG0602	queuosine metabolic process
FKV23_RS12965	COG2885	chlorophyll binding
FKV23_RS12990	COG0824	Thioesterase
FKV23_RS12995	COG2255	four-way junction helicase activity
FKV23_RS13000	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FKV23_RS13005	COG0569	domain protein
FKV23_RS13015	COG0632	four-way junction helicase activity
FKV23_RS13020	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FKV23_RS13025	COG0217	transcriptional regulatory protein
FKV23_RS13065	COG0488	(ABC) transporter
FKV23_RS13075	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FKV23_RS13075	COG4651	solute:proton antiporter activity
FKV23_RS13080	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FKV23_RS13085	COG0406	alpha-ribazole phosphatase activity
FKV23_RS13090	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FKV23_RS13110	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
FKV23_RS13135	COG4206	TonB-dependent receptor
FKV23_RS13140	COG0542	response to heat
FKV23_RS13150	COG3387	PFAM Glycoside hydrolase 15-related
FKV23_RS13155	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
FKV23_RS13185	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FKV23_RS13185	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FKV23_RS13200	COG0045	succinate-CoA ligase (ADP-forming) activity
FKV23_RS13255	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FKV23_RS13265	COG0494	nUDIX hydrolase
FKV23_RS13270	COG0653	protein targeting
FKV23_RS13275	COG0739	heme binding
FKV23_RS13285	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FKV23_RS13300	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FKV23_RS13305	COG1181	Belongs to the D-alanine--D-alanine ligase family
FKV23_RS13325	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FKV23_RS13330	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FKV23_RS13335	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FKV23_RS13345	COG3116	cell division
FKV23_RS13350	COG0275	rRNA processing
FKV23_RS13355	COG2001	Belongs to the MraZ family
FKV23_RS13385	COG0792	nuclease activity
FKV23_RS13390	COG0277	FAD linked oxidase domain protein
FKV23_RS13395	COG1573	uracil-dna glycosylase
FKV23_RS13400	COG0189	ligase activity
FKV23_RS13420	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FKV23_RS13425	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FKV23_RS13445	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FKV23_RS13445	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FKV23_RS13460	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FKV23_RS13465	COG0488	(ABC) transporter
FKV23_RS13470	COG0284	orotidine-5'-phosphate decarboxylase activity
FKV23_RS13485	COG1450	Type ii and iii secretion system protein
FKV23_RS13500	COG3166	PFAM Fimbrial assembly family protein
FKV23_RS13505	COG3156	type II secretion system protein K
FKV23_RS13510	COG4795	General secretion pathway protein
FKV23_RS13515	COG2165	general secretion pathway protein
FKV23_RS13520	COG4970	Tfp pilus assembly protein FimT
FKV23_RS13525	COG2165	general secretion pathway protein
FKV23_RS13530	COG1459	type II secretion system
FKV23_RS13540	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FKV23_RS13560	COG1404	Belongs to the peptidase S8 family
FKV23_RS13580	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FKV23_RS13580	COG0047	phosphoribosylformylglycinamidine synthase activity
FKV23_RS13585	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FKV23_RS13590	COG4974	Belongs to the 'phage' integrase family
FKV23_RS13610	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FKV23_RS13625	COG0456	acetyltransferase
FKV23_RS13635	COG1183	phosphatidylcholine synthase activity
FKV23_RS13645	COG0442	prolyl-tRNA aminoacylation
FKV23_RS13660	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FKV23_RS13665	COG1127	ABC transporter
FKV23_RS13670	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FKV23_RS13670	COG3218	ABC-type transport auxiliary lipoprotein component
FKV23_RS13690	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FKV23_RS13705	COG2086	electron transfer activity
FKV23_RS13715	COG1216	Glycosyl transferase, family 2
FKV23_RS13725	COG0438	transferase activity, transferring glycosyl groups
FKV23_RS13725	COG1216	Glycosyl transferase, family 2
FKV23_RS13730	COG3273	potassium ion transport
FKV23_RS13730	COG0471	metal ion transport
FKV23_RS13735	COG0175	sulfate reduction
FKV23_RS13740	COG0529	Catalyzes the synthesis of activated sulfate
FKV23_RS13740	COG2895	sulfate adenylyltransferase (ATP) activity
FKV23_RS13800	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FKV23_RS13825	COG4106	trans-aconitate 2-methyltransferase activity
FKV23_RS13840	COG0626	cystathionine gamma-synthase activity
FKV23_RS13870	COG0625	glutathione transferase activity
FKV23_RS13880	COG2771	luxR family
FKV23_RS13905	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FKV23_RS13910	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FKV23_RS13915	COG0247	lactate metabolic process
FKV23_RS13925	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FKV23_RS13930	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FKV23_RS13940	COG0134	indole-3-glycerol-phosphate synthase activity
FKV23_RS13945	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FKV23_RS13970	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FKV23_RS13990	COG4651	solute:proton antiporter activity
FKV23_RS13990	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FKV23_RS14005	COG2111	Na H antiporter
FKV23_RS14005	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FKV23_RS14010	COG1006	Multisubunit Na H antiporter MnhC subunit
FKV23_RS14015	COG0651	ATP synthesis coupled electron transport
FKV23_RS14020	COG1863	multisubunit Na H antiporter MnhE subunit
FKV23_RS14025	COG2212	antiporter activity
FKV23_RS14030	COG1320	monovalent cation:proton antiporter activity
FKV23_RS14035	COG0189	ligase activity
FKV23_RS14035	COG4067	protein conserved in archaea
FKV23_RS14050	COG0530	calcium, potassium:sodium antiporter activity
FKV23_RS14060	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
FKV23_RS14095	COG2815	serine threonine protein kinase
FKV23_RS14095	COG0515	serine threonine protein kinase
FKV23_RS14120	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FKV23_RS14145	COG0508	dehydrogenase complex catalyzes the overall conversion of
FKV23_RS14150	COG4991	sh3 domain protein
FKV23_RS14165	COG3706	GGDEF domain
FKV23_RS14175	COG0180	Tryptophanyl-tRNA synthetase
FKV23_RS14185	COG3237	CsbD-like
FKV23_RS14195	COG0010	Belongs to the arginase family
FKV23_RS14210	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FKV23_RS14215	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FKV23_RS14215	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FKV23_RS14250	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FKV23_RS14260	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
FKV23_RS14290	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FKV23_RS14295	COG2010	Cytochrome c
FKV23_RS14295	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FKV23_RS14345	COG2133	pyrroloquinoline quinone binding
FKV23_RS14350	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FKV23_RS14410	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FKV23_RS14425	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FKV23_RS14465	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FKV23_RS14505	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FKV23_RS14530	COG2815	serine threonine protein kinase
FKV23_RS14530	COG0515	serine threonine protein kinase
FKV23_RS14545	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FKV23_RS14550	COG0583	DNA-binding transcription factor activity
FKV23_RS14565	COG2197	response regulator
FKV23_RS14570	COG4585	Histidine kinase
FKV23_RS14580	COG1131	(ABC) transporter
FKV23_RS14590	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FKV23_RS14595	COG1136	(ABC) transporter
FKV23_RS14605	COG0577	efflux transmembrane transporter activity
FKV23_RS14615	COG0697	spore germination
FKV23_RS14625	COG1522	sequence-specific DNA binding
FKV23_RS14640	COG0321	lipoyl(octanoyl) transferase activity
FKV23_RS14645	COG2921	Belongs to the UPF0250 family
FKV23_RS14650	COG1686	Belongs to the peptidase S11 family
FKV23_RS14655	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FKV23_RS14660	COG2951	lytic endotransglycosylase activity
FKV23_RS14665	COG0772	Belongs to the SEDS family
FKV23_RS14670	COG0768	penicillin binding
FKV23_RS14680	COG1792	Involved in formation and maintenance of cell shape
FKV23_RS14685	COG1077	Cell shape determining protein MreB Mrl
FKV23_RS14690	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FKV23_RS14705	COG2226	methyltransferase
FKV23_RS14710	COG2153	protein acetylation
FKV23_RS14730	COG1228	amidohydrolase
FKV23_RS14750	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FKV23_RS14760	COG0583	DNA-binding transcription factor activity
FKV23_RS14780	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FKV23_RS14790	COG2832	Protein of unknown function (DUF454)
FKV23_RS14800	COG1505	serine-type exopeptidase activity
FKV23_RS14820	COG0243	molybdopterin cofactor binding
FKV23_RS14825	COG0471	metal ion transport
FKV23_RS14825	COG3273	potassium ion transport
FKV23_RS14835	COG0437	4 iron, 4 sulfur cluster binding
FKV23_RS14840	COG3302	dmso reductase anchor subunit
FKV23_RS14860	COG0181	hydroxymethylbilane synthase activity
FKV23_RS14905	COG1472	Belongs to the glycosyl hydrolase 3 family
FKV23_RS14910	COG0477	Major facilitator Superfamily
FKV23_RS14920	COG1070	Carbohydrate kinase
FKV23_RS14930	COG1501	Belongs to the glycosyl hydrolase 31 family
FKV23_RS14945	COG3250	beta-galactosidase activity
FKV23_RS14970	COG0800	Aldolase
FKV23_RS14975	COG4948	Mandelate Racemase Muconate Lactonizing
FKV23_RS14985	COG3734	2-keto-3-deoxy-galactonokinase
FKV23_RS14995	COG3507	Belongs to the glycosyl hydrolase 43 family
FKV23_RS14995	COG3693	PFAM glycoside hydrolase, family 10
FKV23_RS14995	COG2382	esterase
FKV23_RS15000	COG3507	Belongs to the glycosyl hydrolase 43 family
FKV23_RS15010	COG4948	Mandelate Racemase Muconate Lactonizing
FKV23_RS15025	COG3250	beta-galactosidase activity
FKV23_RS15030	COG3345	alpha-galactosidase
FKV23_RS15035	COG3534	alpha-L-arabinofuranosidase
FKV23_RS15045	COG4948	Mandelate Racemase Muconate Lactonizing
FKV23_RS15050	COG1501	Belongs to the glycosyl hydrolase 31 family
FKV23_RS15060	COG2017	converts alpha-aldose to the beta-anomer
FKV23_RS15065	COG1172	Belongs to the binding-protein-dependent transport system permease family
FKV23_RS15070	COG1172	Belongs to the binding-protein-dependent transport system permease family
FKV23_RS15075	COG1129	ABC transporter
FKV23_RS15080	COG1879	ABC-type sugar transport system periplasmic component
FKV23_RS15085	COG1012	belongs to the aldehyde dehydrogenase family
FKV23_RS15095	COG0583	DNA-binding transcription factor activity
FKV23_RS15105	COG0129	dihydroxy-acid dehydratase activity
FKV23_RS15110	COG3250	beta-galactosidase activity
FKV23_RS15120	COG3537	Alpha-1,2-mannosidase
FKV23_RS15140	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FKV23_RS15160	COG3402	PFAM membrane-flanked domain
FKV23_RS15175	COG1216	Glycosyl transferase, family 2
FKV23_RS15180	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FKV23_RS15180	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FKV23_RS15185	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FKV23_RS15190	COG0242	peptide deformylase activity
FKV23_RS15195	COG1652	LysM domain
FKV23_RS15200	COG0758	DNA mediated transformation
FKV23_RS15205	COG2922	Belongs to the Smg family
FKV23_RS15240	COG1028	Short-chain dehydrogenase reductase Sdr
FKV23_RS15250	COG0616	signal peptide processing
FKV23_RS15255	COG0534	Mate efflux family protein
FKV23_RS15280	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FKV23_RS15295	COG4585	Histidine kinase
FKV23_RS15320	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FKV23_RS15345	COG1252	NADH dehydrogenase
FKV23_RS15350	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FKV23_RS15360	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FKV23_RS15395	COG1056	cytidyltransferase-related domain
FKV23_RS15395	COG1051	belongs to the nudix hydrolase family
FKV23_RS15400	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FKV23_RS15405	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FKV23_RS15415	COG2201	protein-glutamate methylesterase activity
FKV23_RS15420	COG2177	Part of the ABC transporter FtsEX involved in
FKV23_RS15425	COG2884	Cell division ATP-binding protein ftsE
FKV23_RS15440	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FKV23_RS15460	COG3100	YcgL domain-containing protein
FKV23_RS15465	COG0823	Involved in the tonB-independent uptake of proteins
FKV23_RS15465	COG1506	peptidase
FKV23_RS15465	COG4946	Tricorn protease homolog
FKV23_RS15480	COG3179	chitinase
FKV23_RS15515	COG3409	Peptidoglycan-binding domain 1 protein
FKV23_RS15515	COG3773	Cell wall hydrolase
FKV23_RS15600	COG3702	type iv secretory pathway
FKV23_RS15685	COG2224	Isocitrate lyase
FKV23_RS15690	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FKV23_RS15695	COG0583	DNA-binding transcription factor activity
FKV23_RS15700	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FKV23_RS15710	COG0612	Peptidase, M16
FKV23_RS15715	COG1028	Short-chain dehydrogenase reductase Sdr
FKV23_RS15745	COG0210	DNA helicase
FKV23_RS15755	COG0625	glutathione transferase activity
FKV23_RS15775	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FKV23_RS15790	COG0477	Major facilitator Superfamily
FKV23_RS15795	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FKV23_RS15800	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FKV23_RS15805	COG1845	cytochrome c oxidase, subunit III
FKV23_RS15810	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FKV23_RS15825	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
FKV23_RS15840	COG1028	Short-chain dehydrogenase reductase Sdr
FKV23_RS15845	COG0408	coproporphyrinogen oxidase activity
FKV23_RS15850	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FKV23_RS15855	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FKV23_RS15860	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FKV23_RS15890	COG0183	Belongs to the thiolase family
FKV23_RS15900	COG2909	trisaccharide binding
FKV23_RS15955	COG2032	superoxide dismutase activity
FKV23_RS15960	COG2204	response regulator
FKV23_RS15970	COG3852	Histidine kinase
FKV23_RS15975	COG0004	ammonium transporteR
FKV23_RS15980	COG0347	Belongs to the P(II) protein family
FKV23_RS15990	COG0174	glutamine synthetase
FKV23_RS16000	COG1874	Beta-galactosidase
FKV23_RS16000	COG0366	Alpha amylase catalytic
FKV23_RS16010	COG0366	Alpha amylase catalytic
FKV23_RS16020	COG1082	Xylose isomerase domain protein TIM barrel
FKV23_RS16045	COG0837	glucose binding
FKV23_RS16050	COG1609	Transcriptional regulator
FKV23_RS16055	COG4771	TonB-dependent receptor
FKV23_RS16070	COG1881	PFAM PEBP family protein
FKV23_RS16090	COG2050	protein possibly involved in aromatic compounds catabolism
FKV23_RS16100	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FKV23_RS16130	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FKV23_RS16140	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FKV23_RS16155	COG0738	Major facilitator superfamily
FKV23_RS16160	COG1609	Transcriptional regulator
FKV23_RS16170	COG0800	Aldolase
FKV23_RS16175	COG0129	dihydroxy-acid dehydratase activity
FKV23_RS16180	COG0363	glucosamine-6-phosphate deaminase activity
FKV23_RS16185	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FKV23_RS16190	COG2188	Transcriptional regulator
FKV23_RS16195	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FKV23_RS16200	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FKV23_RS16255	COG0456	acetyltransferase
FKV23_RS16255	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FKV23_RS16290	COG0583	DNA-binding transcription factor activity
FKV23_RS16370	COG1040	competence protein
FKV23_RS16375	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FKV23_RS16380	COG0156	8-amino-7-oxononanoate synthase activity
FKV23_RS16385	COG2267	carboxylic ester hydrolase activity
FKV23_RS16395	COG0697	spore germination
FKV23_RS16420	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FKV23_RS16445	COG4206	TonB-dependent receptor
FKV23_RS16470	COG0729	surface antigen
FKV23_RS16505	COG0519	Catalyzes the synthesis of GMP from XMP
FKV23_RS16505	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FKV23_RS16525	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FKV23_RS16535	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FKV23_RS16550	COG2974	May be involved in recombination
FKV23_RS16555	COG0037	tRNA processing
FKV23_RS16565	COG2937	Belongs to the GPAT DAPAT family
FKV23_RS16600	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
FKV23_RS16610	COG0210	DNA helicase
FKV23_RS16630	COG2815	serine threonine protein kinase
FKV23_RS16630	COG0515	serine threonine protein kinase
FKV23_RS16640	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FKV23_RS16670	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FKV23_RS16710	COG0784	Response regulator, receiver
FKV23_RS16710	COG2205	protein histidine kinase activity
FKV23_RS16725	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FKV23_RS16735	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FKV23_RS16755	COG1192	Involved in chromosome partitioning
FKV23_RS16760	COG0357	Ribosomal RNA small subunit methyltransferase G
FKV23_RS16765	COG2091	lysine biosynthetic process via aminoadipic acid
FKV23_RS16790	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FKV23_RS16815	COG0714	Associated with various cellular activities
FKV23_RS16850	COG0583	DNA-binding transcription factor activity
FKV23_RS16865	COG1187	pseudouridine synthase activity
FKV23_RS16875	COG1643	Atp-dependent helicase
FKV23_RS16940	COG4964	Belongs to the GSP D family
FKV23_RS16980	COG2885	chlorophyll binding
FKV23_RS17000	COG2885	chlorophyll binding
FKV23_RS17000	COG3047	cAMP biosynthetic process
FKV23_RS17005	COG0842	Transport permease protein
FKV23_RS17010	COG1131	(ABC) transporter
FKV23_RS17015	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FKV23_RS17035	COG4555	ABC transporter
FKV23_RS17045	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
FKV23_RS17055	COG0706	membrane insertase activity