locus-tag	class	description
KU6B_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KU6B_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KU6B_RS00025	COG3541	Predicted nucleotidyltransferase
KU6B_RS00040	COG1116	anion transmembrane transporter activity
KU6B_RS00045	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KU6B_RS00060	COG1320	monovalent cation:proton antiporter activity
KU6B_RS00065	COG2212	antiporter activity
KU6B_RS00070	COG1863	multisubunit Na H antiporter MnhE subunit
KU6B_RS00075	COG0651	ATP synthesis coupled electron transport
KU6B_RS00080	COG1006	Multisubunit Na H antiporter MnhC subunit
KU6B_RS00090	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KU6B_RS00100	COG0725	ABC transporter, periplasmic molybdate-binding protein
KU6B_RS00105	COG4149	molybdate abc transporter
KU6B_RS00110	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
KU6B_RS00120	COG3046	protein related to deoxyribodipyrimidine photolyase
KU6B_RS00155	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
KU6B_RS00165	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KU6B_RS00175	COG1959	2 iron, 2 sulfur cluster binding
KU6B_RS00180	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KU6B_RS00185	COG0509	glycine decarboxylation via glycine cleavage system
KU6B_RS00195	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KU6B_RS00195	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KU6B_RS00210	COG0483	inositol monophosphate 1-phosphatase activity
KU6B_RS00220	COG4181	ATPase activity
KU6B_RS00235	COG0644	oxidoreductase
KU6B_RS00240	COG1376	ErfK ybiS ycfS ynhG family protein
KU6B_RS00260	COG1766	The M ring may be actively involved in energy transduction
KU6B_RS00270	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KU6B_RS00275	COG1338	Plays a role in the flagellum-specific transport system
KU6B_RS00280	COG2017	converts alpha-aldose to the beta-anomer
KU6B_RS00290	COG0443	Heat shock 70 kDa protein
KU6B_RS00295	COG1335	isochorismatase
KU6B_RS00300	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KU6B_RS00305	COG2755	lipolytic protein G-D-S-L family
KU6B_RS00305	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
KU6B_RS00315	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KU6B_RS00320	COG0287	Prephenate dehydrogenase
KU6B_RS00330	COG2268	Band 7 protein
KU6B_RS00335	COG1585	Membrane protein implicated in regulation of membrane protease activity
KU6B_RS00345	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KU6B_RS00350	COG0165	Argininosuccinate lyase
KU6B_RS00370	COG0019	diaminopimelate decarboxylase activity
KU6B_RS00385	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KU6B_RS00395	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
KU6B_RS00415	COG0514	ATP-dependent DNA helicase (RecQ)
KU6B_RS00420	COG3022	response to hydroperoxide
KU6B_RS00425	COG2205	protein histidine kinase activity
KU6B_RS00425	COG0784	Response regulator, receiver
KU6B_RS00425	COG5002	protein histidine kinase activity
KU6B_RS00465	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
KU6B_RS00470	COG0156	8-amino-7-oxononanoate synthase activity
KU6B_RS00475	COG0183	Belongs to the thiolase family
KU6B_RS00485	COG3264	Mechanosensitive ion channel
KU6B_RS00485	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
KU6B_RS00500	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KU6B_RS00510	COG0066	3-isopropylmalate dehydratase activity
KU6B_RS00535	COG0473	3-isopropylmalate dehydrogenase activity
KU6B_RS00545	COG0697	spore germination
KU6B_RS00555	COG4974	Belongs to the 'phage' integrase family
KU6B_RS00630	COG2814	Major facilitator Superfamily
KU6B_RS00645	COG0701	Predicted permease
KU6B_RS00670	COG0398	Pfam SNARE associated Golgi protein
KU6B_RS00690	COG0745	RESPONSE REGULATOR receiver
KU6B_RS00735	COG0789	Transcriptional regulator
KU6B_RS00750	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
KU6B_RS00765	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KU6B_RS00770	COG0583	DNA-binding transcription factor activity
KU6B_RS00775	COG1804	L-carnitine dehydratase bile acid-inducible protein F
KU6B_RS00785	COG1733	regulation of RNA biosynthetic process
KU6B_RS00800	COG5507	3-demethylubiquinone-9 3-methyltransferase
KU6B_RS00805	COG0625	glutathione transferase activity
KU6B_RS00810	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KU6B_RS00825	COG1742	UPF0060 membrane protein
KU6B_RS00830	COG0789	Transcriptional regulator
KU6B_RS00840	COG4974	Belongs to the 'phage' integrase family
KU6B_RS00845	COG4974	Belongs to the 'phage' integrase family
KU6B_RS00850	COG4974	Belongs to the 'phage' integrase family
KU6B_RS00860	COG0798	PFAM Bile acid sodium symporter
KU6B_RS00865	COG1028	Short-chain dehydrogenase reductase Sdr
KU6B_RS00870	COG3734	2-keto-3-deoxy-galactonokinase
KU6B_RS00875	COG0800	Aldolase
KU6B_RS00880	COG1136	(ABC) transporter
KU6B_RS00905	COG2217	Heavy metal translocating P-type atpase
KU6B_RS00910	COG0820	rRNA (adenine-C2-)-methyltransferase activity
KU6B_RS00935	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
KU6B_RS00975	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KU6B_RS00980	COG0285	dihydrofolate synthase activity
KU6B_RS00995	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
KU6B_RS01005	COG2271	Major facilitator Superfamily
KU6B_RS01010	COG0596	Alpha beta hydrolase
KU6B_RS01015	COG2423	ornithine cyclodeaminase activity
KU6B_RS01025	COG1671	Belongs to the UPF0178 family
KU6B_RS01030	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
KU6B_RS01050	COG0129	dihydroxy-acid dehydratase activity
KU6B_RS01075	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KU6B_RS01080	COG1177	transmembrane transport
KU6B_RS01085	COG1176	ABC-type spermidine putrescine transport system, permease component I
KU6B_RS01090	COG3842	ATPase activity
KU6B_RS01115	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KU6B_RS01120	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KU6B_RS01140	COG0508	dehydrogenase complex catalyzes the overall conversion of
KU6B_RS01145	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KU6B_RS01150	COG3806	Anti-sigma factor
KU6B_RS01155	COG1595	DNA-templated transcription, initiation
KU6B_RS01175	COG1028	Short-chain dehydrogenase reductase Sdr
KU6B_RS01185	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KU6B_RS01210	COG0284	orotidine-5'-phosphate decarboxylase activity
KU6B_RS01235	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
KU6B_RS01250	COG0076	glutamate decarboxylase activity
KU6B_RS01255	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KU6B_RS01260	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
KU6B_RS01310	COG0842	Transport permease protein
KU6B_RS01335	COG1435	thymidine kinase activity
KU6B_RS01365	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KU6B_RS01385	COG0583	DNA-binding transcription factor activity
KU6B_RS01400	COG3485	protocatechuate 3,4-dioxygenase
KU6B_RS01405	COG3485	protocatechuate 3,4-dioxygenase
KU6B_RS01410	COG3246	L-lysine catabolic process to acetate
KU6B_RS01425	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
KU6B_RS01430	COG0745	RESPONSE REGULATOR receiver
KU6B_RS01435	COG2205	protein histidine kinase activity
KU6B_RS01445	COG1660	Displays ATPase and GTPase activities
KU6B_RS01455	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KU6B_RS01465	COG1250	3-hydroxyacyl-CoA dehydrogenase
KU6B_RS01485	COG0501	Belongs to the peptidase M48B family
KU6B_RS01495	COG0501	Belongs to the peptidase M48B family
KU6B_RS01505	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KU6B_RS01515	COG0300	oxidoreductase activity
KU6B_RS01525	COG2096	Adenosyltransferase
KU6B_RS01530	COG2124	cytochrome p450
KU6B_RS01540	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KU6B_RS01625	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KU6B_RS01630	COG0250	Participates in transcription elongation, termination and antitermination
KU6B_RS01640	COG0583	DNA-binding transcription factor activity
KU6B_RS01650	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KU6B_RS01655	COG0081	regulation of translation
KU6B_RS01675	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KU6B_RS01680	COG0222	ribosome binding
KU6B_RS01685	COG0085	RNA polymerase activity
KU6B_RS01690	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KU6B_RS01705	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KU6B_RS01710	COG0049	tRNA binding
KU6B_RS01715	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KU6B_RS01720	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KU6B_RS01725	COG0051	transcription antitermination factor activity, RNA binding
KU6B_RS01730	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KU6B_RS01735	COG0088	Forms part of the polypeptide exit tunnel
KU6B_RS01740	COG0089	rRNA binding
KU6B_RS01755	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KU6B_RS01760	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KU6B_RS01770	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KU6B_RS01805	COG0255	Belongs to the universal ribosomal protein uL29 family
KU6B_RS01810	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KU6B_RS01815	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KU6B_RS01820	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KU6B_RS01825	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KU6B_RS01830	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KU6B_RS01835	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KU6B_RS01840	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KU6B_RS01845	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KU6B_RS01855	COG1841	ribosomal large subunit assembly
KU6B_RS01860	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KU6B_RS01865	COG2124	cytochrome p450
KU6B_RS01875	COG0513	Belongs to the DEAD box helicase family
KU6B_RS01885	COG0200	Binds to the 23S rRNA
KU6B_RS01890	COG0201	protein transport
KU6B_RS01895	COG0563	adenylate kinase activity
KU6B_RS01905	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KU6B_RS01910	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KU6B_RS01915	COG0202	RNA polymerase activity
KU6B_RS01920	COG0203	ribosomal protein L17
KU6B_RS01925	COG2808	Putative FMN-binding domain
KU6B_RS01930	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KU6B_RS01935	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KU6B_RS01955	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KU6B_RS01965	COG0574	Belongs to the PEP-utilizing enzyme family
KU6B_RS01965	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KU6B_RS01970	COG1522	sequence-specific DNA binding
KU6B_RS01980	COG1024	Enoyl-CoA hydratase
KU6B_RS01980	COG1250	3-hydroxyacyl-CoA dehydrogenase
KU6B_RS02005	COG1840	ABC-type Fe3 transport system, periplasmic component
KU6B_RS02020	COG1178	ABC-type Fe3 transport system permease component
KU6B_RS02060	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
KU6B_RS02060	COG2755	lipolytic protein G-D-S-L family
KU6B_RS02065	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
KU6B_RS02065	COG2755	lipolytic protein G-D-S-L family
KU6B_RS02085	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KU6B_RS02090	COG1858	cytochrome C peroxidase
KU6B_RS02100	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KU6B_RS02105	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KU6B_RS02110	COG0457	Tetratricopeptide repeat
KU6B_RS02125	COG0438	transferase activity, transferring glycosyl groups
KU6B_RS02130	COG0495	leucyl-tRNA aminoacylation
KU6B_RS02155	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KU6B_RS02185	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KU6B_RS02195	COG1136	(ABC) transporter
KU6B_RS02220	COG1175	transmembrane transport
KU6B_RS02250	COG3707	response regulator
KU6B_RS02255	COG1116	anion transmembrane transporter activity
KU6B_RS02255	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KU6B_RS02260	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KU6B_RS02260	COG1116	anion transmembrane transporter activity
KU6B_RS02265	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KU6B_RS02275	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KU6B_RS02280	COG2146	nitrite reductase [NAD(P)H] activity
KU6B_RS02285	COG0243	molybdopterin cofactor binding
KU6B_RS02290	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KU6B_RS02295	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KU6B_RS02295	COG1648	precorrin-2 dehydrogenase activity
KU6B_RS02305	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KU6B_RS02315	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KU6B_RS02320	COG1177	transmembrane transport
KU6B_RS02325	COG1176	ABC-type spermidine putrescine transport system, permease component I
KU6B_RS02330	COG3842	ATPase activity
KU6B_RS02350	COG0583	DNA-binding transcription factor activity
KU6B_RS02365	COG2072	flavoprotein involved in K transport
KU6B_RS02375	COG4650	regulator
KU6B_RS02395	COG3257	ureidoglycine aminohydrolase activity
KU6B_RS02410	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
KU6B_RS02415	COG3195	allantoin biosynthetic process
KU6B_RS02415	COG3648	Uricase
KU6B_RS02420	COG2351	hydroxyisourate hydrolase activity
KU6B_RS02425	COG0583	DNA-binding transcription factor activity
KU6B_RS02435	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KU6B_RS02440	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
KU6B_RS02460	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KU6B_RS02470	COG1116	anion transmembrane transporter activity
KU6B_RS02475	COG1309	transcriptional regulator
KU6B_RS02505	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KU6B_RS02515	COG2226	methyltransferase
KU6B_RS02560	COG3842	ATPase activity
KU6B_RS02570	COG1178	ABC-type Fe3 transport system permease component
KU6B_RS02580	COG2376	Dihydroxyacetone kinase
KU6B_RS02585	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KU6B_RS02600	COG0149	triose-phosphate isomerase activity
KU6B_RS02620	COG0191	fructose-bisphosphate aldolase activity
KU6B_RS02625	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KU6B_RS02665	COG1129	ABC transporter
KU6B_RS02670	COG1172	Belongs to the binding-protein-dependent transport system permease family
KU6B_RS02675	COG1879	ABC-type sugar transport system periplasmic component
KU6B_RS02680	COG0583	DNA-binding transcription factor activity
KU6B_RS02685	COG3534	alpha-L-arabinofuranosidase
KU6B_RS02700	COG1175	transmembrane transport
KU6B_RS02705	COG0395	ABC-type sugar transport system, permease component
KU6B_RS02715	COG1335	isochorismatase
KU6B_RS02745	COG1309	transcriptional regulator
KU6B_RS02750	COG0583	DNA-binding transcription factor activity
KU6B_RS02765	COG3383	formate dehydrogenase (NAD+) activity
KU6B_RS02770	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KU6B_RS02780	COG1720	tRNA m6t6A37 methyltransferase activity
KU6B_RS02785	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KU6B_RS02790	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KU6B_RS02795	COG1120	ATPase activity
KU6B_RS02800	COG1177	transmembrane transport
KU6B_RS02815	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KU6B_RS02825	COG1012	belongs to the aldehyde dehydrogenase family
KU6B_RS02860	COG2186	Transcriptional regulator
KU6B_RS02870	COG1172	Belongs to the binding-protein-dependent transport system permease family
KU6B_RS02875	COG1129	ABC transporter
KU6B_RS02880	COG1879	ABC-type sugar transport system periplasmic component
KU6B_RS02885	COG0583	DNA-binding transcription factor activity
KU6B_RS02890	COG0697	spore germination
KU6B_RS02930	COG0590	tRNA wobble adenosine to inosine editing
KU6B_RS02935	COG4608	Belongs to the ABC transporter superfamily
KU6B_RS02940	COG0444	Belongs to the ABC transporter superfamily
KU6B_RS02955	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KU6B_RS02965	COG0747	negative chemotaxis
KU6B_RS02970	COG2186	Transcriptional regulator
KU6B_RS02980	COG1609	Transcriptional regulator
KU6B_RS02990	COG0673	inositol 2-dehydrogenase activity
KU6B_RS03000	COG1129	ABC transporter
KU6B_RS03005	COG1172	Belongs to the binding-protein-dependent transport system permease family
KU6B_RS03010	COG1172	Belongs to the binding-protein-dependent transport system permease family
KU6B_RS03025	COG3002	Belongs to the UPF0753 family
KU6B_RS03030	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KU6B_RS03035	COG0583	DNA-binding transcription factor activity
KU6B_RS03050	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KU6B_RS03055	COG1522	sequence-specific DNA binding
KU6B_RS03065	COG1012	belongs to the aldehyde dehydrogenase family
KU6B_RS03105	COG0714	Associated with various cellular activities
KU6B_RS03110	COG2031	fatty acid transporter
KU6B_RS03120	COG0318	PFAM AMP-dependent synthetase and ligase
KU6B_RS03140	COG1846	Transcriptional regulator
KU6B_RS03150	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KU6B_RS03150	COG1017	nitric oxide dioxygenase activity
KU6B_RS03175	COG3473	Maleate cis-trans isomerase
KU6B_RS03180	COG0596	Alpha beta hydrolase
KU6B_RS03185	COG2309	aminopeptidase activity
KU6B_RS03190	COG1335	isochorismatase
KU6B_RS03195	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KU6B_RS03240	COG0625	glutathione transferase activity
KU6B_RS03260	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KU6B_RS03295	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KU6B_RS03300	COG0602	queuosine metabolic process
KU6B_RS03305	COG0720	synthase
KU6B_RS03310	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KU6B_RS03350	COG1573	uracil-dna glycosylase
KU6B_RS03385	COG1136	(ABC) transporter
KU6B_RS03400	COG1028	Short-chain dehydrogenase reductase Sdr
KU6B_RS03435	COG0747	negative chemotaxis
KU6B_RS03440	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
KU6B_RS03445	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
KU6B_RS03450	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KU6B_RS03490	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KU6B_RS03500	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KU6B_RS03505	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KU6B_RS03510	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KU6B_RS03515	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KU6B_RS03520	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KU6B_RS03530	COG2095	MarC family integral membrane protein
KU6B_RS03555	COG0596	Alpha beta hydrolase
KU6B_RS03560	COG0842	Transport permease protein
KU6B_RS03565	COG1131	(ABC) transporter
KU6B_RS03570	COG0697	spore germination
KU6B_RS03640	COG1968	undecaprenyl-diphosphatase activity
KU6B_RS03645	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KU6B_RS03650	COG0799	negative regulation of ribosome biogenesis
KU6B_RS03695	COG1902	pentaerythritol trinitrate reductase activity
KU6B_RS03695	COG0446	pyridine nucleotide-disulphide oxidoreductase
KU6B_RS03700	COG0693	protein deglycase activity
KU6B_RS03710	COG0583	DNA-binding transcription factor activity
KU6B_RS03730	COG1058	Belongs to the CinA family
KU6B_RS03730	COG1546	Belongs to the CinA family
KU6B_RS03735	COG1489	DNA binding
KU6B_RS03740	COG1227	inorganic diphosphatase activity
KU6B_RS03750	COG1194	a g-specific adenine glycosylase
KU6B_RS03760	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KU6B_RS03765	COG1804	L-carnitine dehydratase bile acid-inducible protein F
KU6B_RS03790	COG0024	Methionine aminopeptidase
KU6B_RS03800	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KU6B_RS03805	COG0742	ribosomal rna small subunit methyltransferase
KU6B_RS03820	COG2154	pterin-4-alpha-carbinolamine dehydratase
KU6B_RS03830	COG0584	glycerophosphoryl diester phosphodiesterase
KU6B_RS03840	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KU6B_RS03845	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
KU6B_RS03865	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KU6B_RS03870	COG0347	Belongs to the P(II) protein family
KU6B_RS03875	COG0004	ammonium transporteR
KU6B_RS03885	COG2186	Transcriptional regulator
KU6B_RS03890	COG0314	molybdopterin synthase activity
KU6B_RS03900	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KU6B_RS03920	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KU6B_RS03930	COG0571	ribonuclease III activity
KU6B_RS03945	COG0681	Belongs to the peptidase S26 family
KU6B_RS03955	COG0736	holo-[acyl-carrier-protein] synthase activity
KU6B_RS03970	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
KU6B_RS03980	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KU6B_RS03985	COG1758	RNA polymerase activity
KU6B_RS03990	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KU6B_RS04000	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KU6B_RS04020	COG2860	membrane
KU6B_RS04025	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KU6B_RS04030	COG0242	peptide deformylase activity
KU6B_RS04035	COG0242	peptide deformylase activity
KU6B_RS04040	COG0242	peptide deformylase activity
KU6B_RS04045	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KU6B_RS04060	COG0435	Glutathione S-transferase
KU6B_RS04100	COG4175	Glycine betaine
KU6B_RS04120	COG1028	Short-chain dehydrogenase reductase Sdr
KU6B_RS04125	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KU6B_RS04135	COG0436	Aminotransferase
KU6B_RS04170	COG2983	Belongs to the UPF0260 family
KU6B_RS04175	COG0196	riboflavin kinase activity
KU6B_RS04190	COG0469	pyruvate kinase activity
KU6B_RS04205	COG0291	Belongs to the bacterial ribosomal protein bL35 family
KU6B_RS04210	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KU6B_RS04230	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
KU6B_RS04235	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KU6B_RS04255	COG0072	phenylalanine-tRNA ligase activity
KU6B_RS04255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KU6B_RS04335	COG0825	malonyl-CoA metabolic process
KU6B_RS04370	COG4948	Mandelate Racemase Muconate Lactonizing
KU6B_RS04380	COG2885	chlorophyll binding
KU6B_RS04380	COG3047	cAMP biosynthetic process
KU6B_RS04395	COG1403	HNH endonuclease
KU6B_RS04400	COG0824	Thioesterase
KU6B_RS04435	COG2885	chlorophyll binding
KU6B_RS04445	COG0037	tRNA processing
KU6B_RS04450	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KU6B_RS04465	COG2759	Belongs to the formate--tetrahydrofolate ligase family
KU6B_RS04480	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KU6B_RS04485	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KU6B_RS04520	COG3938	Belongs to the proline racemase family
KU6B_RS04525	COG0667	Aldo Keto reductase
KU6B_RS04560	COG1129	ABC transporter
KU6B_RS04595	COG0477	Major facilitator Superfamily
KU6B_RS04620	COG0124	histidyl-tRNA synthetase
KU6B_RS04625	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
KU6B_RS04630	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KU6B_RS04635	COG0625	glutathione transferase activity
KU6B_RS04665	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KU6B_RS04680	COG0583	DNA-binding transcription factor activity
KU6B_RS04720	COG0523	cobalamin synthesis protein
KU6B_RS04735	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
KU6B_RS04755	COG1116	anion transmembrane transporter activity
KU6B_RS04780	COG0803	Belongs to the bacterial solute-binding protein 9 family
KU6B_RS04785	COG1121	(ABC) transporter
KU6B_RS04795	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KU6B_RS04810	COG0784	Response regulator, receiver
KU6B_RS04840	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KU6B_RS04845	COG3237	CsbD-like
KU6B_RS04865	COG3920	Histidine kinase
KU6B_RS04895	COG0628	permease
KU6B_RS04915	COG1072	(Pantothenic acid kinase))
KU6B_RS04925	COG1215	transferase activity, transferring glycosyl groups
KU6B_RS04930	COG0583	DNA-binding transcription factor activity
KU6B_RS04935	COG1176	ABC-type spermidine putrescine transport system, permease component I
KU6B_RS04950	COG3842	ATPase activity
KU6B_RS04955	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KU6B_RS04960	COG3246	L-lysine catabolic process to acetate
KU6B_RS04990	COG2080	2 iron, 2 sulfur cluster binding
KU6B_RS04995	COG1529	Aldehyde oxidase and xanthine dehydrogenase
KU6B_RS05010	COG0402	S-adenosylhomocysteine deaminase activity
KU6B_RS05055	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KU6B_RS05080	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KU6B_RS05090	COG4311	Sarcosine oxidase, delta subunit
KU6B_RS05095	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KU6B_RS05095	COG0446	pyridine nucleotide-disulphide oxidoreductase
KU6B_RS05110	COG0358	DNA primase activity
KU6B_RS05115	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KU6B_RS05135	COG0432	Pfam Uncharacterised protein family UPF0047
KU6B_RS05145	COG1473	amidohydrolase
KU6B_RS05155	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KU6B_RS05155	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KU6B_RS05180	COG2391	methyltransferase activity
KU6B_RS05195	COG0785	Cytochrome C biogenesis protein
KU6B_RS05220	COG3258	Cytochrome c
KU6B_RS05225	COG0737	Belongs to the 5'-nucleotidase family
KU6B_RS05230	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KU6B_RS05245	COG0446	pyridine nucleotide-disulphide oxidoreductase
KU6B_RS05260	COG0740	serine-type endopeptidase activity
KU6B_RS05265	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KU6B_RS05295	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
KU6B_RS05300	COG0439	Biotin carboxylase
KU6B_RS05320	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KU6B_RS05325	COG0410	ABC transporter
KU6B_RS05350	COG3800	Transcriptional regulator
KU6B_RS05350	COG1396	sequence-specific DNA binding
KU6B_RS05355	COG0745	RESPONSE REGULATOR receiver
KU6B_RS05365	COG5002	protein histidine kinase activity
KU6B_RS05410	COG3750	Belongs to the UPF0335 family
KU6B_RS05415	COG2308	Evidence 4 Homologs of previously reported genes of
KU6B_RS05425	COG1305	Transglutaminase-like
KU6B_RS05485	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KU6B_RS05490	COG1804	L-carnitine dehydratase bile acid-inducible protein F
KU6B_RS05505	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KU6B_RS05555	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KU6B_RS05570	COG0583	DNA-binding transcription factor activity
KU6B_RS05575	COG0519	Catalyzes the synthesis of GMP from XMP
KU6B_RS05575	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KU6B_RS05615	COG0235	Class ii aldolase
KU6B_RS05625	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KU6B_RS05630	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KU6B_RS05635	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KU6B_RS05750	COG1175	transmembrane transport
KU6B_RS05755	COG0395	ABC-type sugar transport system, permease component
KU6B_RS05770	COG0583	DNA-binding transcription factor activity
KU6B_RS05775	COG0747	negative chemotaxis
KU6B_RS05780	COG0601	transmembrane transport
KU6B_RS05785	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KU6B_RS05790	COG0444	Belongs to the ABC transporter superfamily
KU6B_RS05795	COG4608	Belongs to the ABC transporter superfamily
KU6B_RS05805	COG1473	amidohydrolase
KU6B_RS05810	COG2072	flavoprotein involved in K transport
KU6B_RS05815	COG3284	Transcriptional regulator
KU6B_RS05820	COG0028	Belongs to the TPP enzyme family
KU6B_RS05830	COG2268	Band 7 protein
KU6B_RS05835	COG1012	belongs to the aldehyde dehydrogenase family
KU6B_RS05860	COG0683	leucine binding
KU6B_RS05865	COG1012	belongs to the aldehyde dehydrogenase family
KU6B_RS05885	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KU6B_RS05900	COG0179	Fumarylacetoacetate (FAA) hydrolase
KU6B_RS05905	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
KU6B_RS05910	COG0625	glutathione transferase activity
KU6B_RS05915	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KU6B_RS05940	COG1012	belongs to the aldehyde dehydrogenase family
KU6B_RS05945	COG5441	Belongs to the UPF0261 family
KU6B_RS06035	COG0709	Synthesizes selenophosphate from selenide and ATP
KU6B_RS06040	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
KU6B_RS06045	COG2201	protein-glutamate methylesterase activity
KU6B_RS06055	COG0745	RESPONSE REGULATOR receiver
KU6B_RS06060	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KU6B_RS06065	COG0835	chemotaxis
KU6B_RS06075	COG0745	RESPONSE REGULATOR receiver
KU6B_RS06125	COG4172	Belongs to the ABC transporter superfamily
KU6B_RS06135	COG0601	transmembrane transport
KU6B_RS06140	COG0747	negative chemotaxis
KU6B_RS06175	COG0183	Belongs to the thiolase family
KU6B_RS06195	COG1960	acyl-CoA dehydrogenase activity
KU6B_RS06230	COG0133	tryptophan synthase activity
KU6B_RS06275	COG0193	aminoacyl-tRNA hydrolase activity
KU6B_RS06290	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KU6B_RS06300	COG1304	FMN binding
KU6B_RS06310	COG2205	protein histidine kinase activity
KU6B_RS06310	COG0784	Response regulator, receiver
KU6B_RS06315	COG0159	tryptophan synthase activity
KU6B_RS06320	COG2326	polyphosphate kinase activity
KU6B_RS06330	COG0534	Mate efflux family protein
KU6B_RS06340	COG0012	GTP binding
KU6B_RS06365	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KU6B_RS06365	COG3008	intermembrane lipid transfer
KU6B_RS06370	COG2995	paraquat-inducible protein a
KU6B_RS06400	COG2855	membrane
KU6B_RS06435	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KU6B_RS06455	COG1053	succinate dehydrogenase
KU6B_RS06465	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
KU6B_RS06515	COG3181	Tripartite tricarboxylate transporter family receptor
KU6B_RS06520	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KU6B_RS06525	COG2188	Transcriptional regulator
KU6B_RS06530	COG1024	Enoyl-CoA hydratase
KU6B_RS06530	COG1250	3-hydroxyacyl-CoA dehydrogenase
KU6B_RS06535	COG0183	Belongs to the thiolase family
KU6B_RS06545	COG1725	Transcriptional regulator
KU6B_RS06550	COG0129	dihydroxy-acid dehydratase activity
KU6B_RS06555	COG1024	Enoyl-CoA hydratase
KU6B_RS06560	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KU6B_RS06575	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KU6B_RS06590	COG1960	acyl-CoA dehydrogenase activity
KU6B_RS06595	COG1960	acyl-CoA dehydrogenase activity
KU6B_RS06610	COG0513	Belongs to the DEAD box helicase family
KU6B_RS06620	COG2186	Transcriptional regulator
KU6B_RS06625	COG3842	ATPase activity
KU6B_RS06665	COG1802	Transcriptional regulator
KU6B_RS06670	COG0697	spore germination
KU6B_RS06680	COG0655	NAD(P)H dehydrogenase (quinone) activity
KU6B_RS06710	COG2133	pyrroloquinoline quinone binding
KU6B_RS06740	COG2205	protein histidine kinase activity
KU6B_RS06740	COG0784	Response regulator, receiver
KU6B_RS06775	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KU6B_RS06825	COG1414	Transcriptional regulator
KU6B_RS06840	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KU6B_RS06850	COG1116	anion transmembrane transporter activity
KU6B_RS06860	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KU6B_RS06875	COG2267	carboxylic ester hydrolase activity
KU6B_RS06885	COG1028	Short-chain dehydrogenase reductase Sdr
KU6B_RS06895	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
KU6B_RS06900	COG1012	belongs to the aldehyde dehydrogenase family
KU6B_RS06910	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KU6B_RS06920	COG1414	Transcriptional regulator
KU6B_RS06965	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KU6B_RS06970	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KU6B_RS06985	COG1396	sequence-specific DNA binding
KU6B_RS06990	COG0156	8-amino-7-oxononanoate synthase activity
KU6B_RS07000	COG3800	Transcriptional regulator
KU6B_RS07000	COG1396	sequence-specific DNA binding
KU6B_RS07010	COG2301	Belongs to the HpcH HpaI aldolase family
KU6B_RS07015	COG0045	succinate-CoA ligase (ADP-forming) activity
KU6B_RS07020	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KU6B_RS07025	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
KU6B_RS07030	COG1804	L-carnitine dehydratase bile acid-inducible protein F
KU6B_RS07040	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
KU6B_RS07050	COG3396	Phenylacetate-CoA oxygenase
KU6B_RS07055	COG3460	Phenylacetate-CoA oxygenase
KU6B_RS07060	COG3396	Phenylacetate-CoA oxygenase
KU6B_RS07065	COG2151	metal-sulfur cluster biosynthetic enzyme
KU6B_RS07070	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KU6B_RS07080	COG1012	belongs to the aldehyde dehydrogenase family
KU6B_RS07080	COG2030	dehydratase
KU6B_RS07085	COG3327	negative regulation of DNA-templated transcription, initiation
KU6B_RS07100	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
KU6B_RS07105	COG3622	Belongs to the hyi family
KU6B_RS07120	COG1082	Xylose isomerase domain protein TIM barrel
KU6B_RS07125	COG0673	inositol 2-dehydrogenase activity
KU6B_RS07130	COG1129	ABC transporter
KU6B_RS07170	COG2066	Belongs to the glutaminase family
KU6B_RS07180	COG0747	negative chemotaxis
KU6B_RS07190	COG0444	Belongs to the ABC transporter superfamily
KU6B_RS07195	COG4608	Belongs to the ABC transporter superfamily
KU6B_RS07200	COG1522	sequence-specific DNA binding
KU6B_RS07245	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KU6B_RS07250	COG3350	monooxygenase activity
KU6B_RS07280	COG0459	protein refolding
KU6B_RS07305	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
KU6B_RS07315	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KU6B_RS07325	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KU6B_RS07345	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KU6B_RS07355	COG3001	Fructosamine kinase
KU6B_RS07360	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KU6B_RS07370	COG1132	(ABC) transporter
KU6B_RS07380	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KU6B_RS07385	COG1136	(ABC) transporter
KU6B_RS07400	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KU6B_RS07565	COG0583	DNA-binding transcription factor activity
KU6B_RS07590	COG0583	DNA-binding transcription factor activity
KU6B_RS07605	COG3119	arylsulfatase activity
KU6B_RS07660	COG1522	sequence-specific DNA binding
KU6B_RS07675	COG2072	flavoprotein involved in K transport
KU6B_RS07705	COG1177	transmembrane transport
KU6B_RS07710	COG3842	ATPase activity
KU6B_RS07735	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KU6B_RS07765	COG0668	transmembrane transport
KU6B_RS07800	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KU6B_RS07810	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KU6B_RS07810	COG0446	pyridine nucleotide-disulphide oxidoreductase
KU6B_RS07820	COG0729	surface antigen
KU6B_RS07830	COG0589	response to stress
KU6B_RS07840	COG2358	TRAP transporter, solute receptor (TAXI family
KU6B_RS07850	COG3246	L-lysine catabolic process to acetate
KU6B_RS07855	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KU6B_RS07865	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
KU6B_RS07870	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
KU6B_RS07880	COG1233	COG1233 Phytoene dehydrogenase and related
KU6B_RS07890	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
KU6B_RS07895	COG5621	secreted hydrolase
KU6B_RS07900	COG1233	COG1233 Phytoene dehydrogenase and related
KU6B_RS07905	COG0142	geranyltranstransferase activity
KU6B_RS07910	COG0500	methyltransferase
KU6B_RS07920	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
KU6B_RS07925	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
KU6B_RS07930	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
KU6B_RS07965	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KU6B_RS07975	COG0156	8-amino-7-oxononanoate synthase activity
KU6B_RS07985	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
KU6B_RS08020	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
KU6B_RS08035	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
KU6B_RS08080	COG1172	Belongs to the binding-protein-dependent transport system permease family
KU6B_RS08105	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KU6B_RS08120	COG0601	transmembrane transport
KU6B_RS08125	COG0747	negative chemotaxis
KU6B_RS08130	COG0583	DNA-binding transcription factor activity
KU6B_RS08150	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KU6B_RS08155	COG1454	alcohol dehydrogenase
KU6B_RS08165	COG3395	kinase activity
KU6B_RS08180	COG1024	Enoyl-CoA hydratase
KU6B_RS08190	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KU6B_RS08225	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KU6B_RS08230	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KU6B_RS08235	COG0277	FAD linked oxidase domain protein
KU6B_RS08250	COG1609	Transcriptional regulator
KU6B_RS08270	COG0129	dihydroxy-acid dehydratase activity
KU6B_RS08275	COG1028	Short-chain dehydrogenase reductase Sdr
KU6B_RS08280	COG0697	spore germination
KU6B_RS08285	COG1028	Short-chain dehydrogenase reductase Sdr
KU6B_RS08295	COG2721	sulfolactate sulfo-lyase activity
KU6B_RS08300	COG5285	phytanoyl-CoA dioxygenase
KU6B_RS08315	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KU6B_RS08330	COG1028	Short-chain dehydrogenase reductase Sdr
KU6B_RS08335	COG3958	Transketolase
KU6B_RS08340	COG3959	Transketolase, thiamine diphosphate binding domain
KU6B_RS08345	COG1960	acyl-CoA dehydrogenase activity
KU6B_RS08355	COG3246	L-lysine catabolic process to acetate
KU6B_RS08365	COG0673	inositol 2-dehydrogenase activity
KU6B_RS08375	COG0583	DNA-binding transcription factor activity
KU6B_RS08385	COG1278	Cold shock
KU6B_RS08390	COG1393	Belongs to the ArsC family
KU6B_RS08410	COG3220	belongs to the UPF0276 family
KU6B_RS08420	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KU6B_RS08470	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KU6B_RS08485	COG0670	Belongs to the BI1 family
KU6B_RS08515	COG0552	protein localization to endoplasmic reticulum
KU6B_RS08540	COG0019	diaminopimelate decarboxylase activity
KU6B_RS08555	COG1832	CoA-binding protein
KU6B_RS08570	COG0140	phosphoribosyl-ATP diphosphatase activity
KU6B_RS08580	COG0107	imidazoleglycerol-phosphate synthase activity
KU6B_RS08605	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KU6B_RS08610	COG0131	Imidazoleglycerol-phosphate dehydratase
KU6B_RS08640	COG0346	lactoylglutathione lyase activity
KU6B_RS08650	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KU6B_RS08665	COG0210	DNA helicase
KU6B_RS08675	COG1522	sequence-specific DNA binding
KU6B_RS08685	COG2968	Membrane
KU6B_RS08690	COG2873	o-acetylhomoserine
KU6B_RS08730	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KU6B_RS08735	COG0154	amidase activity
KU6B_RS08750	COG1396	sequence-specific DNA binding
KU6B_RS08750	COG3800	Transcriptional regulator
KU6B_RS08755	COG2814	Major facilitator Superfamily
KU6B_RS08800	COG4770	biotin carboxylase activity
KU6B_RS08835	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
KU6B_RS08850	COG0248	Ppx GppA phosphatase
KU6B_RS08855	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KU6B_RS08880	COG0628	permease
KU6B_RS08890	COG0442	prolyl-tRNA aminoacylation
KU6B_RS08900	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KU6B_RS08910	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KU6B_RS08915	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KU6B_RS08920	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KU6B_RS08925	COG3773	Cell wall hydrolase
KU6B_RS08925	COG3409	Peptidoglycan-binding domain 1 protein
KU6B_RS08930	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KU6B_RS08930	COG0574	Belongs to the PEP-utilizing enzyme family
KU6B_RS08935	COG0751	glycine-tRNA ligase activity
KU6B_RS09015	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KU6B_RS09025	COG1522	sequence-specific DNA binding
KU6B_RS09040	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KU6B_RS09055	COG1802	Transcriptional regulator
KU6B_RS09065	COG0505	Belongs to the CarA family
KU6B_RS09070	COG1610	YqeY-like protein
KU6B_RS09120	COG0321	lipoyl(octanoyl) transferase activity
KU6B_RS09160	COG1804	L-carnitine dehydratase bile acid-inducible protein F
KU6B_RS09255	COG0183	Belongs to the thiolase family
KU6B_RS09285	COG4214	carbohydrate transport
KU6B_RS09315	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KU6B_RS09370	COG3852	Histidine kinase
KU6B_RS09385	COG0489	protein tyrosine kinase activity
KU6B_RS09425	COG3383	formate dehydrogenase (NAD+) activity
KU6B_RS09430	COG0437	4 iron, 4 sulfur cluster binding
KU6B_RS09455	COG1116	anion transmembrane transporter activity
KU6B_RS09465	COG1910	domain protein
KU6B_RS09480	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
KU6B_RS09485	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KU6B_RS09510	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KU6B_RS09535	COG0308	aminopeptidase N
KU6B_RS09540	COG0415	Belongs to the DNA photolyase family
KU6B_RS09570	COG1160	GTP binding
KU6B_RS09585	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KU6B_RS09590	COG3591	Belongs to the peptidase S1B family
KU6B_RS09595	COG1862	Preprotein translocase
KU6B_RS09600	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KU6B_RS09605	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KU6B_RS09615	COG3737	Protein of unknown function (DUF498/DUF598)
KU6B_RS09620	COG4133	protoheme IX ABC transporter activity
KU6B_RS09625	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KU6B_RS09630	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KU6B_RS09640	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KU6B_RS09720	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KU6B_RS09735	COG2391	methyltransferase activity
KU6B_RS09750	COG0601	transmembrane transport
KU6B_RS09760	COG4172	Belongs to the ABC transporter superfamily
KU6B_RS09765	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KU6B_RS09770	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KU6B_RS09775	COG1473	amidohydrolase
KU6B_RS09780	COG1473	amidohydrolase
KU6B_RS09790	COG1162	GTPase activity
KU6B_RS09805	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KU6B_RS09810	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KU6B_RS09830	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KU6B_RS09885	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KU6B_RS09915	COG2833	Protein of unknown function (DUF455)
KU6B_RS09920	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KU6B_RS09950	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KU6B_RS09965	COG2945	thiolester hydrolase activity
KU6B_RS09970	COG1959	2 iron, 2 sulfur cluster binding
KU6B_RS09990	COG0396	ATPase activity
KU6B_RS09995	COG0719	Fe-S assembly protein
KU6B_RS10010	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KU6B_RS10015	COG2813	Specifically methylates the guanine in position
KU6B_RS10045	COG1204	response to ionizing radiation
KU6B_RS10055	COG3436	PFAM IS66 Orf2 family protein
KU6B_RS10150	COG5489	Protein of unknown function (DUF736)
KU6B_RS10195	COG0741	lytic transglycosylase activity
KU6B_RS10250	COG4962	Type ii secretion system protein e
KU6B_RS10265	COG3451	type IV secretory pathway VirB4
KU6B_RS10280	COG3846	protein secretion by the type IV secretion system
KU6B_RS10295	COG2948	multi-organism process
KU6B_RS10305	COG0583	DNA-binding transcription factor activity
KU6B_RS10310	COG0071	Belongs to the small heat shock protein (HSP20) family
KU6B_RS10315	COG0071	Belongs to the small heat shock protein (HSP20) family
KU6B_RS10325	COG0501	Belongs to the peptidase M48B family
KU6B_RS10335	COG0542	response to heat
KU6B_RS10365	COG0071	Belongs to the small heat shock protein (HSP20) family
KU6B_RS10410	COG1280	lysine exporter protein (LysE YggA)
KU6B_RS10415	COG1522	sequence-specific DNA binding
KU6B_RS10425	COG1280	lysine exporter protein (LysE YggA)
KU6B_RS10440	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KU6B_RS10445	COG0583	DNA-binding transcription factor activity
KU6B_RS10460	COG1476	TRANSCRIPTIONal
KU6B_RS10495	COG1881	PFAM PEBP family protein
KU6B_RS10500	COG2271	Major facilitator Superfamily
KU6B_RS10505	COG0662	Cupin 2, conserved barrel domain protein
KU6B_RS10545	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
KU6B_RS10550	COG2258	MOSC domain
KU6B_RS10555	COG0505	Belongs to the CarA family
KU6B_RS10565	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KU6B_RS10570	COG1268	BioY protein
KU6B_RS10595	COG2814	Major facilitator Superfamily
KU6B_RS10600	COG4974	Belongs to the 'phage' integrase family
KU6B_RS10610	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KU6B_RS10610	COG0446	pyridine nucleotide-disulphide oxidoreductase
KU6B_RS10635	COG0745	RESPONSE REGULATOR receiver
KU6B_RS10645	COG0463	Glycosyl transferase, family 2
KU6B_RS10645	COG1216	Glycosyl transferase, family 2
KU6B_RS10655	COG1132	(ABC) transporter
KU6B_RS10660	COG3119	arylsulfatase activity
KU6B_RS10665	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KU6B_RS10675	COG0446	pyridine nucleotide-disulphide oxidoreductase
KU6B_RS10700	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KU6B_RS10710	COG1959	2 iron, 2 sulfur cluster binding
KU6B_RS10715	COG1846	Transcriptional regulator
KU6B_RS10725	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KU6B_RS10730	COG1917	Cupin 2, conserved barrel domain protein
KU6B_RS10735	COG0527	aspartate kinase activity
KU6B_RS10745	COG1858	cytochrome C peroxidase
KU6B_RS10755	COG2197	response regulator
KU6B_RS10775	COG0544	peptidyl-prolyl cis-trans isomerase activity
KU6B_RS10785	COG5310	Homospermidine synthase
KU6B_RS10800	COG0359	binds to the 23S rRNA
KU6B_RS10805	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KU6B_RS10810	COG0360	Binds together with S18 to 16S ribosomal RNA
KU6B_RS10820	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KU6B_RS10840	COG3956	TIGRFAM MazG family protein
KU6B_RS10845	COG1473	amidohydrolase
KU6B_RS10850	COG1473	amidohydrolase
KU6B_RS10855	COG0010	Belongs to the arginase family
KU6B_RS10865	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KU6B_RS10870	COG2890	protein-(glutamine-N5) methyltransferase activity
KU6B_RS10880	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KU6B_RS10885	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
KU6B_RS10895	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
KU6B_RS10910	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KU6B_RS10920	COG3577	Aspartyl protease
KU6B_RS10925	COG2095	MarC family integral membrane protein
KU6B_RS10935	COG0105	UTP biosynthetic process
KU6B_RS10945	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KU6B_RS10965	COG4695	Portal protein
KU6B_RS11050	COG0508	dehydrogenase complex catalyzes the overall conversion of
KU6B_RS11060	COG0508	dehydrogenase complex catalyzes the overall conversion of
KU6B_RS11060	COG0022	dehydrogenase e1 component
KU6B_RS11070	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KU6B_RS11075	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
KU6B_RS11090	COG0583	DNA-binding transcription factor activity
KU6B_RS11145	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KU6B_RS11155	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KU6B_RS11175	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KU6B_RS11180	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KU6B_RS11210	COG1960	acyl-CoA dehydrogenase activity
KU6B_RS11225	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KU6B_RS11230	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KU6B_RS11260	COG1024	Enoyl-CoA hydratase
KU6B_RS11280	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KU6B_RS11285	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KU6B_RS11295	COG0649	NAD binding
KU6B_RS11415	COG0713	ATP synthesis coupled electron transport
KU6B_RS11430	COG1007	ATP synthesis coupled electron transport
KU6B_RS11440	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KU6B_RS11455	COG0513	Belongs to the DEAD box helicase family
KU6B_RS11500	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KU6B_RS11585	COG1858	cytochrome C peroxidase
KU6B_RS11590	COG0542	response to heat
KU6B_RS11600	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KU6B_RS11605	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
KU6B_RS11620	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KU6B_RS11630	COG1982	Orn Lys Arg decarboxylase major
KU6B_RS11645	COG0175	sulfate reduction
KU6B_RS11650	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KU6B_RS11660	COG1648	precorrin-2 dehydrogenase activity
KU6B_RS11660	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KU6B_RS11665	COG1522	sequence-specific DNA binding
KU6B_RS11685	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KU6B_RS11690	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
KU6B_RS11695	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
KU6B_RS11700	COG0149	triose-phosphate isomerase activity
KU6B_RS11725	COG2814	Major facilitator Superfamily
KU6B_RS11745	COG2151	metal-sulfur cluster biosynthetic enzyme
KU6B_RS11750	COG0189	ligase activity
KU6B_RS11750	COG4067	protein conserved in archaea
KU6B_RS11755	COG1741	Belongs to the pirin family
KU6B_RS11785	COG0860	N-Acetylmuramoyl-L-alanine amidase
KU6B_RS11785	COG3409	Peptidoglycan-binding domain 1 protein
KU6B_RS11790	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KU6B_RS11795	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KU6B_RS11835	COG1804	L-carnitine dehydratase bile acid-inducible protein F
KU6B_RS11860	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KU6B_RS11860	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KU6B_RS11875	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KU6B_RS11880	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KU6B_RS11910	COG2076	Multidrug Resistance protein
KU6B_RS11930	COG0840	transmembrane signaling receptor activity
KU6B_RS11940	COG2308	Evidence 4 Homologs of previously reported genes of
KU6B_RS11940	COG2307	Protein conserved in bacteria
KU6B_RS11945	COG1305	Transglutaminase-like
KU6B_RS11990	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KU6B_RS11995	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KU6B_RS12005	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KU6B_RS12015	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KU6B_RS12060	COG0196	riboflavin kinase activity
KU6B_RS12125	COG0006	proline dipeptidase activity
KU6B_RS12140	COG1879	ABC-type sugar transport system periplasmic component
KU6B_RS12145	COG1028	Short-chain dehydrogenase reductase Sdr
KU6B_RS12150	COG1172	Belongs to the binding-protein-dependent transport system permease family
KU6B_RS12155	COG1172	Belongs to the binding-protein-dependent transport system permease family
KU6B_RS12160	COG1129	ABC transporter
KU6B_RS12165	COG0457	Tetratricopeptide repeat
KU6B_RS12195	COG3135	benzoate transporter
KU6B_RS12210	COG4139	cobalamin transport
KU6B_RS12215	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
KU6B_RS12235	COG1335	isochorismatase
KU6B_RS12290	COG0261	This protein binds to 23S rRNA in the presence of protein L20
KU6B_RS12290	COG3743	rRNA binding
KU6B_RS12295	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KU6B_RS12305	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KU6B_RS12310	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KU6B_RS12315	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KU6B_RS12340	COG0352	thiamine-phosphate diphosphorylase activity
KU6B_RS12365	COG1612	heme a metabolic process
KU6B_RS12390	COG5425	PFAM Usg family protein
KU6B_RS12410	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KU6B_RS12455	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KU6B_RS12470	COG0248	Ppx GppA phosphatase
KU6B_RS12475	COG5507	3-demethylubiquinone-9 3-methyltransferase
KU6B_RS12495	COG1028	Short-chain dehydrogenase reductase Sdr
KU6B_RS12500	COG1250	3-hydroxyacyl-CoA dehydrogenase
KU6B_RS12500	COG0824	Thioesterase
KU6B_RS12535	COG1595	DNA-templated transcription, initiation
KU6B_RS12540	COG0156	8-amino-7-oxononanoate synthase activity
KU6B_RS12550	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
KU6B_RS12570	COG0436	Aminotransferase
KU6B_RS12575	COG0860	N-Acetylmuramoyl-L-alanine amidase
KU6B_RS12585	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KU6B_RS12615	COG0440	acetolactate synthase activity
KU6B_RS12670	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
KU6B_RS12690	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
KU6B_RS12700	COG0800	Aldolase
KU6B_RS12705	COG0129	dihydroxy-acid dehydratase activity
KU6B_RS12720	COG3842	ATPase activity
KU6B_RS12750	COG2059	Chromate
KU6B_RS12780	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KU6B_RS12795	COG2249	NAD(P)H dehydrogenase (quinone) activity
KU6B_RS12800	COG2249	NAD(P)H dehydrogenase (quinone) activity
KU6B_RS12820	COG0673	inositol 2-dehydrogenase activity
KU6B_RS12830	COG1172	Belongs to the binding-protein-dependent transport system permease family
KU6B_RS12855	COG0840	transmembrane signaling receptor activity
KU6B_RS12865	COG1733	regulation of RNA biosynthetic process
KU6B_RS12870	COG0702	epimerase
KU6B_RS12875	COG0583	DNA-binding transcription factor activity
KU6B_RS12890	COG3384	dioxygenase
KU6B_RS12895	COG0435	Glutathione S-transferase
KU6B_RS12905	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KU6B_RS12930	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KU6B_RS12950	COG1074	ATP-dependent DNA helicase activity
KU6B_RS12965	COG0420	3'-5' exonuclease activity
KU6B_RS13060	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KU6B_RS13080	COG4166	transmembrane transport
KU6B_RS13085	COG1028	Short-chain dehydrogenase reductase Sdr
KU6B_RS13100	COG2313	pseudouridylate synthase activity
KU6B_RS13110	COG0583	DNA-binding transcription factor activity
KU6B_RS13115	COG1960	acyl-CoA dehydrogenase activity
KU6B_RS13125	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KU6B_RS13130	COG2197	response regulator
KU6B_RS13135	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KU6B_RS13140	COG0052	Belongs to the universal ribosomal protein uS2 family
KU6B_RS13150	COG0745	RESPONSE REGULATOR receiver
KU6B_RS13155	COG0704	Plays a role in the regulation of phosphate uptake
KU6B_RS13160	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KU6B_RS13180	COG5002	protein histidine kinase activity
KU6B_RS13185	COG0626	cystathionine gamma-synthase activity
KU6B_RS13200	COG0194	GDP metabolic process
KU6B_RS13205	COG1561	YicC-like family, N-terminal region
KU6B_RS13215	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
KU6B_RS13235	COG2133	pyrroloquinoline quinone binding
KU6B_RS13300	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KU6B_RS13305	COG2814	Major facilitator Superfamily
KU6B_RS13310	COG0538	isocitrate dehydrogenase activity
KU6B_RS13335	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KU6B_RS13355	COG1278	Cold shock
KU6B_RS13360	COG0259	pyridoxamine-phosphate oxidase activity
KU6B_RS13365	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KU6B_RS13375	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
KU6B_RS13395	COG2166	iron-sulfur cluster assembly
KU6B_RS13405	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
KU6B_RS13415	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KU6B_RS13420	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
KU6B_RS13440	COG0433	COG0433 Predicted ATPase
KU6B_RS13450	COG2354	Protein conserved in bacteria
KU6B_RS13475	COG2204	response regulator
KU6B_RS13485	COG0047	phosphoribosylformylglycinamidine synthase activity
KU6B_RS13490	COG1064	alcohol dehydrogenase
KU6B_RS13495	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KU6B_RS13525	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
KU6B_RS13560	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
KU6B_RS13570	COG2326	polyphosphate kinase activity
KU6B_RS13575	COG1309	transcriptional regulator
KU6B_RS13590	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
KU6B_RS13595	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KU6B_RS13610	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KU6B_RS13615	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KU6B_RS13630	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KU6B_RS13635	COG2264	protein methyltransferase activity
KU6B_RS13640	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KU6B_RS13645	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KU6B_RS13655	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KU6B_RS13660	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KU6B_RS13675	COG0482	sulfurtransferase activity
KU6B_RS13700	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KU6B_RS13705	COG0416	fatty acid biosynthetic process
KU6B_RS13710	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KU6B_RS13715	COG0776	regulation of translation
KU6B_RS13735	COG0717	Belongs to the dCTP deaminase family
KU6B_RS13745	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KU6B_RS13750	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KU6B_RS13765	COG0018	arginyl-trna synthetase
KU6B_RS13770	COG3263	regulation of cellular component size
KU6B_RS13775	COG0232	Belongs to the dGTPase family. Type 2 subfamily
KU6B_RS13790	COG0316	Belongs to the HesB IscA family
KU6B_RS13825	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KU6B_RS13845	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KU6B_RS13850	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KU6B_RS13860	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KU6B_RS13865	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KU6B_RS13875	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KU6B_RS13880	COG0750	zinc metalloprotease
KU6B_RS13900	COG0233	cytoplasmic translational termination
KU6B_RS13925	COG0747	negative chemotaxis
KU6B_RS13930	COG0601	transmembrane transport
KU6B_RS13950	COG0741	lytic transglycosylase activity
KU6B_RS13950	COG1196	nuclear chromosome segregation
KU6B_RS13950	COG0739	heme binding
KU6B_RS13955	COG0629	single-stranded DNA binding
KU6B_RS13960	COG0517	IMP dehydrogenase activity
KU6B_RS13960	COG1994	Peptidase M50
KU6B_RS13970	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KU6B_RS13985	COG4974	Belongs to the 'phage' integrase family
KU6B_RS13990	COG4536	flavin adenine dinucleotide binding
KU6B_RS14045	COG0010	Belongs to the arginase family
KU6B_RS14060	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KU6B_RS14060	COG1116	anion transmembrane transporter activity
KU6B_RS14100	COG3842	ATPase activity
KU6B_RS14130	COG0402	S-adenosylhomocysteine deaminase activity
KU6B_RS14135	COG3842	ATPase activity
KU6B_RS14140	COG1177	transmembrane transport
KU6B_RS14145	COG1176	ABC-type spermidine putrescine transport system, permease component I
KU6B_RS14155	COG0583	DNA-binding transcription factor activity
KU6B_RS14165	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KU6B_RS14170	COG0726	polysaccharide deacetylase
KU6B_RS14175	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
KU6B_RS14175	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KU6B_RS14235	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
KU6B_RS14240	COG0352	thiamine-phosphate diphosphorylase activity
KU6B_RS14245	COG0351	phosphomethylpyrimidine kinase
KU6B_RS14250	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KU6B_RS14260	COG3932	Exopolysaccharide synthesis, ExoD
KU6B_RS14305	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KU6B_RS14310	COG0517	IMP dehydrogenase activity
KU6B_RS14310	COG0617	tRNA 3'-terminal CCA addition
KU6B_RS14310	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KU6B_RS14330	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
KU6B_RS14340	COG1953	Uracil, thiamine, allantoin
KU6B_RS14345	COG0438	transferase activity, transferring glycosyl groups
KU6B_RS14350	COG1960	acyl-CoA dehydrogenase activity
KU6B_RS14370	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KU6B_RS14380	COG0688	phosphatidylethanolamine metabolic process
KU6B_RS14385	COG1183	phosphatidylcholine synthase activity
KU6B_RS14395	COG0346	lactoylglutathione lyase activity
KU6B_RS14400	COG3842	ATPase activity
KU6B_RS14405	COG0366	Alpha amylase catalytic
KU6B_RS14415	COG1175	transmembrane transport
KU6B_RS14425	COG1609	Transcriptional regulator
KU6B_RS14430	COG2723	6-phospho-beta-galactosidase activity
KU6B_RS14435	COG0837	glucose binding
KU6B_RS14445	COG0148	phosphopyruvate hydratase activity
KU6B_RS14450	COG0784	Response regulator, receiver
KU6B_RS14450	COG4191	Histidine kinase
KU6B_RS14455	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
KU6B_RS14460	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KU6B_RS14470	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KU6B_RS14485	COG0583	DNA-binding transcription factor activity
KU6B_RS14490	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KU6B_RS14495	COG0501	Belongs to the peptidase M48B family
KU6B_RS14500	COG4335	DNA alkylation repair
KU6B_RS14505	COG1028	Short-chain dehydrogenase reductase Sdr
KU6B_RS14535	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KU6B_RS14560	COG2885	chlorophyll binding
KU6B_RS14620	COG0418	dihydroorotase activity
KU6B_RS14635	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KU6B_RS14645	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
KU6B_RS14650	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KU6B_RS14655	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KU6B_RS14680	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KU6B_RS14700	COG4221	oxidoreductase activity
KU6B_RS14705	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
KU6B_RS14710	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KU6B_RS14720	COG2226	methyltransferase
KU6B_RS14735	COG0805	protein transport
KU6B_RS14740	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KU6B_RS14745	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KU6B_RS14760	COG3588	fructose-bisphosphate aldolase
KU6B_RS14775	COG0785	Cytochrome C biogenesis protein
KU6B_RS14780	COG0425	Belongs to the sulfur carrier protein TusA family
KU6B_RS14790	COG1530	ribonuclease E activity
KU6B_RS14790	COG1530	ribonuclease E activity
KU6B_RS14795	COG4191	Histidine kinase
KU6B_RS14795	COG0784	Response regulator, receiver
KU6B_RS14800	COG2084	Dehydrogenase
KU6B_RS14820	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KU6B_RS14825	COG1923	regulation of RNA biosynthetic process
KU6B_RS14835	COG0569	domain protein
KU6B_RS14845	COG2204	response regulator
KU6B_RS14850	COG5000	phosphorelay sensor kinase activity
KU6B_RS14855	COG2204	response regulator
KU6B_RS14860	COG3852	Histidine kinase
KU6B_RS14865	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KU6B_RS14870	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
KU6B_RS14870	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
KU6B_RS14875	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KU6B_RS14880	COG1546	Belongs to the CinA family
KU6B_RS14885	COG0004	ammonium transporteR
KU6B_RS14900	COG2867	negative regulation of translational initiation
KU6B_RS14930	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KU6B_RS14945	COG5598	trimethylamine methyltransferase
KU6B_RS14970	COG3710	Transcriptional regulator
KU6B_RS14975	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KU6B_RS14975	COG0519	Catalyzes the synthesis of GMP from XMP
KU6B_RS14985	COG0646	methionine synthase
KU6B_RS14985	COG1410	methionine synthase
KU6B_RS15015	COG5012	cobalamin binding
KU6B_RS15025	COG0393	Putative heavy-metal-binding
KU6B_RS15055	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KU6B_RS15060	COG0134	indole-3-glycerol-phosphate synthase activity
KU6B_RS15065	COG0315	cyclic pyranopterin monophosphate synthase activity
KU6B_RS15070	COG0303	'Molybdopterin
KU6B_RS15075	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KU6B_RS15080	COG0658	competence protein
KU6B_RS15080	COG2333	competence protein COMEC
KU6B_RS15085	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KU6B_RS15090	COG0372	Belongs to the citrate synthase family
KU6B_RS15095	COG1024	Enoyl-CoA hydratase
KU6B_RS15110	COG3088	subunit of a heme lyase
KU6B_RS15140	COG0166	Belongs to the GPI family
KU6B_RS15150	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KU6B_RS15170	COG0517	IMP dehydrogenase activity
KU6B_RS15170	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
KU6B_RS15175	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
KU6B_RS15200	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KU6B_RS15205	COG3264	Mechanosensitive ion channel
KU6B_RS15205	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
KU6B_RS15215	COG0494	nUDIX hydrolase
KU6B_RS15225	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KU6B_RS15235	COG0415	Belongs to the DNA photolyase family
KU6B_RS15240	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KU6B_RS15245	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KU6B_RS15260	COG0604	alcohol dehydrogenase
KU6B_RS15295	COG2885	chlorophyll binding
KU6B_RS15310	COG1629	transport
KU6B_RS15315	COG3720	iron ion transport
KU6B_RS15320	COG4558	Periplasmic binding protein
KU6B_RS15325	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KU6B_RS15330	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
KU6B_RS15355	COG0811	peptide transport
KU6B_RS15375	COG1126	abc transporter atp-binding protein
KU6B_RS15415	COG3842	ATPase activity
KU6B_RS15420	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KU6B_RS15430	COG0583	DNA-binding transcription factor activity
KU6B_RS15440	COG1335	isochorismatase
KU6B_RS15450	COG0154	amidase activity
KU6B_RS15455	COG0287	Prephenate dehydrogenase
KU6B_RS15475	COG0673	inositol 2-dehydrogenase activity
KU6B_RS15480	COG1172	Belongs to the binding-protein-dependent transport system permease family
KU6B_RS15485	COG1129	ABC transporter
KU6B_RS15495	COG1879	ABC-type sugar transport system periplasmic component
KU6B_RS15500	COG1850	ribulose-bisphosphate carboxylase activity
KU6B_RS15510	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
KU6B_RS15515	COG2894	cell division
KU6B_RS15570	COG1120	ATPase activity
KU6B_RS15575	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KU6B_RS15600	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KU6B_RS15650	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KU6B_RS15670	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
KU6B_RS15725	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KU6B_RS15735	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KU6B_RS15760	COG2962	Rard protein
KU6B_RS15790	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KU6B_RS15790	COG0446	pyridine nucleotide-disulphide oxidoreductase
KU6B_RS15805	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KU6B_RS15815	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KU6B_RS15835	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KU6B_RS15860	COG0667	Aldo Keto reductase
KU6B_RS15875	COG0310	cobalt ion transport
KU6B_RS15905	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KU6B_RS15905	COG1648	precorrin-2 dehydrogenase activity
KU6B_RS15910	COG1797	cobyrinic acid a,c-diamide synthase activity
KU6B_RS15915	COG2875	Belongs to the precorrin methyltransferase family
KU6B_RS15930	COG2099	Precorrin-6x reductase
KU6B_RS15985	COG1492	cobalamin metabolic process
KU6B_RS15995	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
KU6B_RS16015	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
KU6B_RS16020	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
KU6B_RS16045	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KU6B_RS16055	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KU6B_RS16085	COG0563	adenylate kinase activity
KU6B_RS16095	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KU6B_RS16100	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KU6B_RS16115	COG5002	protein histidine kinase activity
KU6B_RS16115	COG2176	DNA-directed DNA polymerase activity
KU6B_RS16125	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KU6B_RS16165	COG0673	inositol 2-dehydrogenase activity
KU6B_RS16190	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KU6B_RS16195	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KU6B_RS16200	COG1414	Transcriptional regulator
KU6B_RS16215	COG3483	tryptophan 2,3-dioxygenase activity
KU6B_RS16220	COG0515	serine threonine protein kinase
KU6B_RS16220	COG2815	serine threonine protein kinase
KU6B_RS16230	COG0631	protein serine/threonine phosphatase activity
KU6B_RS16260	COG4166	transmembrane transport
KU6B_RS16265	COG0601	transmembrane transport
KU6B_RS16270	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KU6B_RS16300	COG2721	sulfolactate sulfo-lyase activity
KU6B_RS16305	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KU6B_RS16310	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KU6B_RS16385	COG1063	alcohol dehydrogenase
KU6B_RS16390	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
KU6B_RS16400	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KU6B_RS16405	COG1802	Transcriptional regulator
KU6B_RS16410	COG1312	Catalyzes the dehydration of D-mannonate
KU6B_RS16415	COG0246	Mannitol dehydrogenase
KU6B_RS16430	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
KU6B_RS16450	COG1028	Short-chain dehydrogenase reductase Sdr
KU6B_RS16450	COG3347	Dehydrogenase
KU6B_RS16460	COG1879	ABC-type sugar transport system periplasmic component
KU6B_RS16465	COG1129	ABC transporter
KU6B_RS16470	COG1172	Belongs to the binding-protein-dependent transport system permease family
KU6B_RS16475	COG1172	Belongs to the binding-protein-dependent transport system permease family
KU6B_RS16480	COG3254	rhamnose metabolic process
KU6B_RS16490	COG4191	Histidine kinase
KU6B_RS16490	COG0784	Response regulator, receiver
KU6B_RS16560	COG0601	transmembrane transport
KU6B_RS16565	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KU6B_RS16570	COG0747	negative chemotaxis
KU6B_RS16575	COG1802	Transcriptional regulator
KU6B_RS16595	COG1618	nucleotide phosphatase activity, acting on free nucleotides
KU6B_RS16595	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
KU6B_RS16605	COG0303	'Molybdopterin
KU6B_RS16610	COG0288	reversible hydration of carbon dioxide
KU6B_RS16615	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KU6B_RS16620	COG2181	nitrate reductase activity
KU6B_RS16625	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
KU6B_RS16630	COG1140	nitrate reductase beta subunit
KU6B_RS16640	COG2223	nitrite transmembrane transporter activity
KU6B_RS16645	COG2223	nitrite transmembrane transporter activity
KU6B_RS16660	COG2132	Multicopper oxidase
KU6B_RS16670	COG3794	PFAM blue (type 1) copper domain protein
KU6B_RS16700	COG0714	Associated with various cellular activities
KU6B_RS16710	COG2010	Cytochrome c
KU6B_RS16730	COG3386	PFAM SMP-30 Gluconolaconase
KU6B_RS16745	COG1129	ABC transporter
KU6B_RS16750	COG1879	ABC-type sugar transport system periplasmic component
KU6B_RS16755	COG4585	Histidine kinase
KU6B_RS16835	COG0863	Belongs to the N(4) N(6)-methyltransferase family
KU6B_RS16845	COG2909	trisaccharide binding
KU6B_RS16850	COG0601	transmembrane transport
KU6B_RS16880	COG0747	negative chemotaxis
KU6B_RS16885	COG3321	synthase
KU6B_RS16885	COG4221	oxidoreductase activity
KU6B_RS16885	COG0604	alcohol dehydrogenase
KU6B_RS16885	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KU6B_RS16890	COG0022	dehydrogenase e1 component
KU6B_RS16910	COG1116	anion transmembrane transporter activity
KU6B_RS16920	COG3836	Belongs to the HpcH HpaI aldolase family
KU6B_RS16950	COG2963	transposase activity
KU6B_RS17010	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KU6B_RS17020	COG0489	protein tyrosine kinase activity
KU6B_RS17030	COG0525	valine-tRNA ligase activity
KU6B_RS17040	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KU6B_RS17050	COG1469	GTP cyclohydrolase I activity
KU6B_RS17075	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
KU6B_RS17100	COG2267	carboxylic ester hydrolase activity
KU6B_RS17110	COG1793	dna ligase
KU6B_RS17140	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KU6B_RS17160	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
KU6B_RS17165	COG4106	trans-aconitate 2-methyltransferase activity
KU6B_RS17170	COG3119	arylsulfatase activity
KU6B_RS17210	COG1943	Transposase
KU6B_RS17215	COG0217	transcriptional regulatory protein
KU6B_RS17220	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KU6B_RS17220	COG0519	Catalyzes the synthesis of GMP from XMP
KU6B_RS17225	COG0471	metal ion transport
KU6B_RS17225	COG3273	potassium ion transport
KU6B_RS17250	COG0587	DNA-directed DNA polymerase activity
KU6B_RS17285	COG0330	HflC and HflK could
KU6B_RS17290	COG0330	HflC and HflK could
KU6B_RS17305	COG0659	secondary active sulfate transmembrane transporter activity
KU6B_RS17320	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KU6B_RS17335	COG1595	DNA-templated transcription, initiation
KU6B_RS17380	COG0006	proline dipeptidase activity
KU6B_RS17410	COG0277	FAD linked oxidase domain protein
KU6B_RS17435	COG0497	DNA recombination
KU6B_RS17440	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KU6B_RS17445	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
KU6B_RS17450	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KU6B_RS17455	COG0849	cell division
KU6B_RS17460	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KU6B_RS17465	COG1181	Belongs to the D-alanine--D-alanine ligase family
KU6B_RS17470	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KU6B_RS17490	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KU6B_RS17495	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KU6B_RS17510	COG2081	HI0933 family
KU6B_RS17515	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KU6B_RS17520	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KU6B_RS17530	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KU6B_RS17545	COG0275	rRNA processing
KU6B_RS17550	COG2001	Belongs to the MraZ family
KU6B_RS17640	COG4397	Mu-like prophage major head subunit gpT
KU6B_RS17660	COG2369	cell adhesion
KU6B_RS17670	COG4383	Mu-like prophage protein gp29
KU6B_RS17865	COG0811	peptide transport
KU6B_RS17885	COG0084	hydrolase, TatD family'
KU6B_RS17890	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KU6B_RS17890	COG0321	lipoyl(octanoyl) transferase activity
KU6B_RS17900	COG0697	spore germination
KU6B_RS17910	COG2239	Acts as a magnesium transporter
KU6B_RS17950	COG0504	CTP synthase activity
KU6B_RS17975	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
KU6B_RS18000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KU6B_RS18015	COG4160	amino acid transport
KU6B_RS18020	COG0174	glutamine synthetase
KU6B_RS18030	COG0174	glutamine synthetase
KU6B_RS18035	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KU6B_RS18040	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KU6B_RS18050	COG1570	exodeoxyribonuclease VII activity
KU6B_RS18055	COG0151	Belongs to the GarS family
KU6B_RS18065	COG0697	spore germination
KU6B_RS18085	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KU6B_RS18105	COG0483	inositol monophosphate 1-phosphatase activity
KU6B_RS18110	COG1396	sequence-specific DNA binding
KU6B_RS18115	COG3321	synthase
KU6B_RS18115	COG1028	Short-chain dehydrogenase reductase Sdr
KU6B_RS18115	COG0604	alcohol dehydrogenase
KU6B_RS18150	COG0564	pseudouridine synthase activity
KU6B_RS18160	COG3971	2-oxopent-4-enoate hydratase activity
KU6B_RS18165	COG0179	Fumarylacetoacetate (FAA) hydrolase
KU6B_RS18180	COG3384	dioxygenase
KU6B_RS18195	COG1846	Transcriptional regulator
KU6B_RS18200	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KU6B_RS18205	COG0154	amidase activity
KU6B_RS18215	COG2267	carboxylic ester hydrolase activity
KU6B_RS18245	COG1609	Transcriptional regulator
KU6B_RS18250	COG1028	Short-chain dehydrogenase reductase Sdr
KU6B_RS18255	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KU6B_RS18270	COG0395	ABC-type sugar transport system, permease component
KU6B_RS18295	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KU6B_RS18310	COG0395	ABC-type sugar transport system, permease component
KU6B_RS18315	COG1175	transmembrane transport
KU6B_RS18320	COG3842	ATPase activity
KU6B_RS18325	COG3842	ATPase activity
KU6B_RS18335	COG1349	DNA-binding transcription factor activity
KU6B_RS18355	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KU6B_RS18395	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KU6B_RS18400	COG1846	Transcriptional regulator
KU6B_RS18410	COG1024	Enoyl-CoA hydratase
KU6B_RS18455	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KU6B_RS18465	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KU6B_RS18465	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KU6B_RS18475	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KU6B_RS18495	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KU6B_RS18500	COG1121	(ABC) transporter
KU6B_RS18505	COG0735	belongs to the Fur family
KU6B_RS18515	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
KU6B_RS18535	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
KU6B_RS18555	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KU6B_RS18575	COG5328	Belongs to the UPF0262 family
KU6B_RS18585	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KU6B_RS18595	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KU6B_RS18610	COG1519	Transferase
KU6B_RS18635	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KU6B_RS18645	COG2132	Multicopper oxidase
KU6B_RS18675	COG0110	maltose O-acetyltransferase activity
KU6B_RS18680	COG0659	secondary active sulfate transmembrane transporter activity
KU6B_RS18685	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KU6B_RS18695	COG1280	lysine exporter protein (LysE YggA)
KU6B_RS18710	COG3243	poly(R)-hydroxyalkanoic acid synthase
KU6B_RS18740	COG1754	DNA topoisomerase type I activity
KU6B_RS18740	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KU6B_RS18750	COG0758	DNA mediated transformation
KU6B_RS18770	COG0109	protoheme IX farnesyltransferase activity
KU6B_RS18780	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
KU6B_RS18790	COG3346	SURF1 family
KU6B_RS18800	COG0612	Peptidase, M16
KU6B_RS18850	COG4964	Belongs to the GSP D family
KU6B_RS18910	COG3794	PFAM blue (type 1) copper domain protein
KU6B_RS18930	COG1136	(ABC) transporter
KU6B_RS18935	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KU6B_RS18940	COG1012	belongs to the aldehyde dehydrogenase family
KU6B_RS18945	COG1522	sequence-specific DNA binding
KU6B_RS18950	COG2423	ornithine cyclodeaminase activity
KU6B_RS18955	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KU6B_RS18960	COG0006	proline dipeptidase activity
KU6B_RS18965	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KU6B_RS18970	COG1063	alcohol dehydrogenase
KU6B_RS18975	COG5463	Belongs to the UPF0441 family
KU6B_RS19000	COG0546	phosphoglycolate phosphatase activity
KU6B_RS19000	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KU6B_RS19065	COG1136	(ABC) transporter
KU6B_RS19105	COG1850	ribulose-bisphosphate carboxylase activity
KU6B_RS19115	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
KU6B_RS19125	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KU6B_RS19130	COG1609	Transcriptional regulator
KU6B_RS19150	COG0446	pyridine nucleotide-disulphide oxidoreductase
KU6B_RS19150	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KU6B_RS19170	COG4638	Rieske (2fe-2S)
KU6B_RS19215	COG2186	Transcriptional regulator
KU6B_RS19220	COG0683	leucine binding
KU6B_RS19230	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KU6B_RS19235	COG4311	Sarcosine oxidase, delta subunit
KU6B_RS19240	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KU6B_RS19240	COG0446	pyridine nucleotide-disulphide oxidoreductase
KU6B_RS19275	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KU6B_RS19280	COG0004	ammonium transporteR
KU6B_RS19290	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KU6B_RS19295	COG2218	PFAM glutamate synthase alpha subunit domain protein
KU6B_RS19300	COG0069	glutamate synthase activity
KU6B_RS19305	COG0174	glutamine synthetase
KU6B_RS19310	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KU6B_RS19315	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KU6B_RS19320	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KU6B_RS19330	COG0045	succinate-CoA ligase (ADP-forming) activity
KU6B_RS19340	COG2197	response regulator
KU6B_RS19360	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KU6B_RS19375	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KU6B_RS19380	COG2759	Belongs to the formate--tetrahydrofolate ligase family
KU6B_RS19385	COG3383	formate dehydrogenase (NAD+) activity
KU6B_RS19400	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KU6B_RS19400	COG0512	Glutamine amidotransferase of anthranilate synthase
KU6B_RS19425	COG0546	phosphoglycolate phosphatase activity
KU6B_RS19470	COG0596	Alpha beta hydrolase
KU6B_RS19475	COG0583	DNA-binding transcription factor activity
KU6B_RS19480	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KU6B_RS19485	COG2515	1-aminocyclopropane-1-carboxylate deaminase
KU6B_RS19515	COG0481	GTPase activity
KU6B_RS19545	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KU6B_RS19550	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KU6B_RS19565	COG0227	Belongs to the bacterial ribosomal protein bL28 family
KU6B_RS19570	COG1703	isobutyryl-CoA mutase activity
KU6B_RS19580	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KU6B_RS19585	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KU6B_RS19610	COG1473	amidohydrolase
KU6B_RS19630	COG0101	tRNA pseudouridine synthase activity
KU6B_RS19635	COG3106	COG3106 Predicted ATPase
KU6B_RS19645	COG3768	UPF0283 membrane protein
KU6B_RS19675	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KU6B_RS19690	COG2197	response regulator
KU6B_RS19695	COG5002	protein histidine kinase activity
KU6B_RS19695	COG2205	protein histidine kinase activity
KU6B_RS19695	COG0784	Response regulator, receiver
KU6B_RS19705	COG0318	PFAM AMP-dependent synthetase and ligase
KU6B_RS19710	COG1720	tRNA m6t6A37 methyltransferase activity
KU6B_RS19745	COG1129	ABC transporter
KU6B_RS19770	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
KU6B_RS19770	COG0493	'glutamate synthase
KU6B_RS19780	COG1309	transcriptional regulator
KU6B_RS19810	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
KU6B_RS19815	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KU6B_RS19820	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KU6B_RS19840	COG1024	Enoyl-CoA hydratase
KU6B_RS19850	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
KU6B_RS19885	COG4166	transmembrane transport
KU6B_RS19890	COG4174	ABC transporter (Permease)
KU6B_RS19900	COG4172	Belongs to the ABC transporter superfamily
KU6B_RS19905	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KU6B_RS19910	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KU6B_RS19915	COG0384	phenazine biosynthesis protein PhzF
KU6B_RS19940	COG2010	Cytochrome c
KU6B_RS19945	COG0583	DNA-binding transcription factor activity
KU6B_RS19950	COG0348	domain, Protein
KU6B_RS19970	COG1522	sequence-specific DNA binding
KU6B_RS19975	COG0686	Belongs to the AlaDH PNT family
KU6B_RS19980	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KU6B_RS19985	COG1970	mechanosensitive ion channel activity
KU6B_RS19990	COG0625	glutathione transferase activity
KU6B_RS20035	COG0768	penicillin binding
KU6B_RS20040	COG0772	Belongs to the SEDS family
KU6B_RS20045	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KU6B_RS20070	COG1960	acyl-CoA dehydrogenase activity
KU6B_RS20085	COG2130	NADP-dependent
KU6B_RS20110	COG0604	alcohol dehydrogenase
KU6B_RS20130	COG0813	purine-nucleoside phosphorylase activity
KU6B_RS20145	COG0019	diaminopimelate decarboxylase activity
KU6B_RS20185	COG2030	dehydratase
KU6B_RS20215	COG0039	L-malate dehydrogenase activity
KU6B_RS20220	COG0045	succinate-CoA ligase (ADP-forming) activity
KU6B_RS20250	COG0567	Dehydrogenase, E1 component
KU6B_RS20255	COG0508	dehydrogenase complex catalyzes the overall conversion of
KU6B_RS20325	COG2884	Cell division ATP-binding protein ftsE
KU6B_RS20340	COG1116	anion transmembrane transporter activity
KU6B_RS20350	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KU6B_RS20365	COG0776	regulation of translation
KU6B_RS20370	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KU6B_RS20415	COG1846	Transcriptional regulator
KU6B_RS20420	COG0745	RESPONSE REGULATOR receiver
KU6B_RS20430	COG1722	exodeoxyribonuclease VII activity
KU6B_RS20435	COG0142	geranyltranstransferase activity
KU6B_RS20440	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KU6B_RS20475	COG3842	ATPase activity
KU6B_RS20490	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KU6B_RS20500	COG0745	RESPONSE REGULATOR receiver
KU6B_RS20505	COG1846	Transcriptional regulator
KU6B_RS20510	COG1764	response to oxidative stress
KU6B_RS20525	COG1185	polyribonucleotide nucleotidyltransferase activity
KU6B_RS20540	COG0523	cobalamin synthesis protein
KU6B_RS20545	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KU6B_RS20590	COG3118	belongs to the thioredoxin family
KU6B_RS20605	COG0450	alkyl hydroperoxide reductase
KU6B_RS20620	COG0564	pseudouridine synthase activity
KU6B_RS20655	COG1366	Belongs to the anti-sigma-factor antagonist family
KU6B_RS20665	COG0405	Gamma-glutamyltransferase
KU6B_RS20685	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KU6B_RS20710	COG2030	dehydratase
KU6B_RS20745	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KU6B_RS20750	COG0612	Peptidase, M16
KU6B_RS20755	COG0612	Peptidase, M16
KU6B_RS20770	COG0138	bifunctional purine biosynthesis protein purh
KU6B_RS20780	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KU6B_RS20780	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KU6B_RS20795	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KU6B_RS20810	COG0312	modulator of DNA gyrase
KU6B_RS20825	COG1519	Transferase
KU6B_RS20830	COG1663	tetraacyldisaccharide 4'-kinase activity
KU6B_RS20845	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KU6B_RS20915	COG4191	Histidine kinase
KU6B_RS20940	COG3383	formate dehydrogenase (NAD+) activity
KU6B_RS20945	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KU6B_RS20960	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KU6B_RS20965	COG1214	PFAM Peptidase M22, glycoprotease
KU6B_RS21000	COG0730	response to heat
KU6B_RS21015	COG0322	excinuclease ABC activity
KU6B_RS21020	COG1028	Short-chain dehydrogenase reductase Sdr
KU6B_RS21035	COG0616	signal peptide processing
KU6B_RS21035	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KU6B_RS21055	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KU6B_RS21065	COG1192	Involved in chromosome partitioning
KU6B_RS21080	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
KU6B_RS21105	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KU6B_RS21110	COG0840	transmembrane signaling receptor activity
KU6B_RS21145	COG1278	Cold shock
KU6B_RS21150	COG1607	acyl-coa hydrolase
KU6B_RS21155	COG4154	Belongs to the RbsD FucU family
KU6B_RS21160	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
KU6B_RS21170	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
KU6B_RS21200	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
KU6B_RS21205	COG0832	Belongs to the urease beta subunit family
KU6B_RS21215	COG0831	urea catabolic process
KU6B_RS21235	COG1172	Belongs to the binding-protein-dependent transport system permease family
KU6B_RS21250	COG0840	transmembrane signaling receptor activity
KU6B_RS21285	COG0765	amino acid transport
KU6B_RS21290	COG1126	abc transporter atp-binding protein
KU6B_RS21315	COG0673	inositol 2-dehydrogenase activity
KU6B_RS21320	COG1609	Transcriptional regulator
KU6B_RS21325	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KU6B_RS21330	COG3962	Belongs to the TPP enzyme family
KU6B_RS21350	COG3718	enzyme involved in inositol metabolism
KU6B_RS21355	COG0277	FAD linked oxidase domain protein
KU6B_RS21370	COG2816	NAD+ diphosphatase activity
KU6B_RS21380	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KU6B_RS21420	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KU6B_RS21430	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KU6B_RS21460	COG0318	PFAM AMP-dependent synthetase and ligase
KU6B_RS21480	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KU6B_RS21485	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KU6B_RS21490	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
KU6B_RS21495	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KU6B_RS21505	COG0281	malic enzyme
KU6B_RS21505	COG0280	phosphate acetyltransferase
KU6B_RS21525	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KU6B_RS21530	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KU6B_RS21535	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
KU6B_RS21545	COG3739	integral membrane protein
KU6B_RS21575	COG0667	Aldo Keto reductase
KU6B_RS21595	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KU6B_RS21605	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KU6B_RS21620	COG1047	Peptidyl-prolyl cis-trans
KU6B_RS21660	COG0154	amidase activity
KU6B_RS21665	COG0318	PFAM AMP-dependent synthetase and ligase
KU6B_RS21680	COG2135	peptidase activity
KU6B_RS21690	COG1803	Methylglyoxal synthase
KU6B_RS21695	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
KU6B_RS21705	COG3246	L-lysine catabolic process to acetate
KU6B_RS21710	COG1250	3-hydroxyacyl-CoA dehydrogenase
KU6B_RS21715	COG3622	Belongs to the hyi family
KU6B_RS21720	COG0235	Class ii aldolase
KU6B_RS21725	COG3395	kinase activity
KU6B_RS21785	COG2358	TRAP transporter, solute receptor (TAXI family
KU6B_RS21795	COG3119	arylsulfatase activity
KU6B_RS21815	COG1132	(ABC) transporter
KU6B_RS21830	COG0737	Belongs to the 5'-nucleotidase family
KU6B_RS21845	COG0135	phosphoribosylanthranilate isomerase activity
KU6B_RS21855	COG0776	regulation of translation
KU6B_RS21870	COG0539	negative regulation of cytoplasmic translation
KU6B_RS21895	COG3454	Phosphonate metabolism
KU6B_RS21900	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
KU6B_RS21910	COG4778	phosphonate C-P lyase system protein PhnL
KU6B_RS21915	COG4107	phosphonate C-P lyase system protein PhnK
KU6B_RS21920	COG3627	carbon phosphorus lyase activity
KU6B_RS21930	COG3626	phosphonate metabolism
KU6B_RS21940	COG3624	Phosphonate C-P lyase system protein PhnG
KU6B_RS21950	COG3454	Phosphonate metabolism
KU6B_RS21960	COG3639	organic phosphonate transmembrane transporter activity
KU6B_RS21965	COG3639	organic phosphonate transmembrane transporter activity
KU6B_RS21970	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
KU6B_RS21990	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KU6B_RS21995	COG2200	EAL domain
KU6B_RS22005	COG1028	Short-chain dehydrogenase reductase Sdr
KU6B_RS22015	COG0583	DNA-binding transcription factor activity
KU6B_RS22025	COG2890	protein-(glutamine-N5) methyltransferase activity
KU6B_RS22035	COG0142	geranyltranstransferase activity
KU6B_RS22040	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KU6B_RS22050	COG3620	sequence-specific DNA binding
KU6B_RS22050	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KU6B_RS22050	COG0617	tRNA 3'-terminal CCA addition
KU6B_RS22065	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KU6B_RS22075	COG0303	'Molybdopterin
KU6B_RS22085	COG1763	Mo-molybdopterin cofactor biosynthetic process
KU6B_RS22090	COG0746	molybdenum cofactor guanylyltransferase activity
KU6B_RS22095	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KU6B_RS22130	COG0009	L-threonylcarbamoyladenylate synthase
KU6B_RS22135	COG1678	Uncharacterized ACR, COG1678
KU6B_RS22145	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KU6B_RS22155	COG0521	Mo-molybdopterin cofactor biosynthetic process
KU6B_RS22165	COG1280	lysine exporter protein (LysE YggA)
KU6B_RS22170	COG1573	uracil-dna glycosylase
KU6B_RS22175	COG0540	Belongs to the ATCase OTCase family
KU6B_RS22200	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KU6B_RS22275	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KU6B_RS22280	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KU6B_RS22285	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KU6B_RS22300	COG0306	phosphate transporter
KU6B_RS22305	COG0587	DNA-directed DNA polymerase activity
KU6B_RS22315	COG2897	thiosulfate sulfurtransferase activity
KU6B_RS22325	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KU6B_RS22335	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
KU6B_RS22360	COG3128	pkhd-type hydroxylase
KU6B_RS22370	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KU6B_RS22375	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KU6B_RS22380	COG1073	alpha beta
KU6B_RS22395	COG2186	Transcriptional regulator
KU6B_RS22400	COG0747	negative chemotaxis
KU6B_RS22410	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KU6B_RS22430	COG4948	Mandelate Racemase Muconate Lactonizing
KU6B_RS22450	COG0542	response to heat
KU6B_RS22455	COG0542	response to heat
KU6B_RS22540	COG0583	DNA-binding transcription factor activity
KU6B_RS22565	COG0179	Fumarylacetoacetate (FAA) hydrolase
KU6B_RS22570	COG1028	Short-chain dehydrogenase reductase Sdr
KU6B_RS22575	COG2721	sulfolactate sulfo-lyase activity
KU6B_RS22580	COG2721	sulfolactate sulfo-lyase activity
KU6B_RS22590	COG0673	inositol 2-dehydrogenase activity
KU6B_RS22595	COG3254	rhamnose metabolic process
KU6B_RS22605	COG3842	ATPase activity
KU6B_RS22610	COG0395	ABC-type sugar transport system, permease component
KU6B_RS22615	COG1175	transmembrane transport
KU6B_RS22710	COG1476	TRANSCRIPTIONal
KU6B_RS22715	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
KU6B_RS22740	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
KU6B_RS22770	COG1609	Transcriptional regulator
KU6B_RS22775	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KU6B_RS22785	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KU6B_RS22790	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KU6B_RS22805	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KU6B_RS22815	COG4535	Mg2 and Co2 transporter CorC
KU6B_RS22820	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KU6B_RS22825	COG1702	phosphate starvation-inducible protein PhoH
KU6B_RS22840	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KU6B_RS22850	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KU6B_RS22865	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KU6B_RS22875	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KU6B_RS22890	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KU6B_RS23110	COG1783	phage Terminase large subunit
KU6B_RS23255	COG3723	Recombinational DNA repair protein, rece pathway
KU6B_RS23325	COG1522	sequence-specific DNA binding
KU6B_RS23350	COG0483	inositol monophosphate 1-phosphatase activity
KU6B_RS23390	COG1846	Transcriptional regulator
KU6B_RS23425	COG3920	Histidine kinase
KU6B_RS23445	COG0187	DNA topoisomerase II activity
KU6B_RS23555	COG3119	arylsulfatase activity
KU6B_RS23575	COG3119	arylsulfatase activity
KU6B_RS23585	COG1116	anion transmembrane transporter activity
KU6B_RS23590	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KU6B_RS23595	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KU6B_RS23630	COG3676	manually curated
KU6B_RS23675	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KU6B_RS23680	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
KU6B_RS23685	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KU6B_RS23695	COG0646	methionine synthase
KU6B_RS23695	COG1410	methionine synthase
KU6B_RS23710	COG1122	ATPase activity
KU6B_RS23715	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KU6B_RS23730	COG0183	Belongs to the thiolase family
KU6B_RS23755	COG2022	thiamine diphosphate biosynthetic process
KU6B_RS23820	COG0556	nucleotide-excision repair
KU6B_RS23830	COG1278	Cold shock
KU6B_RS23855	COG3118	belongs to the thioredoxin family
KU6B_RS23920	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
KU6B_RS23930	COG4143	(ABC) transporter
KU6B_RS23940	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KU6B_RS23945	COG0840	transmembrane signaling receptor activity
KU6B_RS23970	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KU6B_RS23985	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
KU6B_RS23990	COG0459	protein refolding
KU6B_RS23995	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KU6B_RS24010	COG0039	L-malate dehydrogenase activity
KU6B_RS24015	COG0697	spore germination
KU6B_RS24035	COG0339	signal peptide processing
KU6B_RS24040	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KU6B_RS24045	COG0756	dUTP diphosphatase activity
KU6B_RS24050	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KU6B_RS24065	COG0625	glutathione transferase activity
KU6B_RS24070	COG0606	chelatase, subunit chli
KU6B_RS24085	COG0792	nuclease activity
KU6B_RS24090	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KU6B_RS24100	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
KU6B_RS24125	COG0180	Tryptophanyl-tRNA synthetase
KU6B_RS24145	COG2255	four-way junction helicase activity
KU6B_RS24150	COG0632	four-way junction helicase activity
KU6B_RS24175	COG0543	2 iron, 2 sulfur cluster binding
KU6B_RS24175	COG0633	Ferredoxin
KU6B_RS24190	COG0662	Cupin 2, conserved barrel domain protein
KU6B_RS24195	COG2391	methyltransferase activity
KU6B_RS24200	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KU6B_RS24205	COG0181	hydroxymethylbilane synthase activity
KU6B_RS24215	COG1028	Short-chain dehydrogenase reductase Sdr
KU6B_RS24215	COG0604	alcohol dehydrogenase
KU6B_RS24215	COG3321	synthase
KU6B_RS24225	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KU6B_RS24240	COG1686	Belongs to the peptidase S11 family
KU6B_RS24250	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
KU6B_RS24255	COG2813	Specifically methylates the guanine in position
KU6B_RS24260	COG1028	Short-chain dehydrogenase reductase Sdr
KU6B_RS24265	COG0408	coproporphyrinogen oxidase activity
KU6B_RS24270	COG2162	N-hydroxyarylamine O-acetyltransferase activity
KU6B_RS24280	COG0590	tRNA wobble adenosine to inosine editing
KU6B_RS24285	COG1187	pseudouridine synthase activity
KU6B_RS24305	COG3853	Toxic anion resistance protein (TelA)
KU6B_RS24340	COG1490	D-aminoacyl-tRNA deacylase activity
KU6B_RS24375	COG1858	cytochrome C peroxidase
KU6B_RS24395	COG5000	phosphorelay sensor kinase activity
KU6B_RS24400	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KU6B_RS24410	COG0230	Belongs to the bacterial ribosomal protein bL34 family
KU6B_RS24415	COG0594	ribonuclease P activity
KU6B_RS24420	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
KU6B_RS24425	COG0037	tRNA processing
KU6B_RS24430	COG3300	MHYT domain
KU6B_RS24430	COG5001	Diguanylate cyclase
KU6B_RS24435	COG0706	membrane insertase activity
KU6B_RS24445	COG0218	Necessary for normal cell division and for the maintenance of normal septation
KU6B_RS24450	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KU6B_RS24465	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KU6B_RS24480	COG0564	pseudouridine synthase activity
KU6B_RS24505	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KU6B_RS24520	COG2115	Belongs to the xylose isomerase family
KU6B_RS24525	COG1070	Carbohydrate kinase
KU6B_RS24535	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KU6B_RS24560	COG1522	sequence-specific DNA binding
KU6B_RS24565	COG0492	ferredoxin-NADP+ reductase activity
KU6B_RS24575	COG0529	Catalyzes the synthesis of activated sulfate
KU6B_RS24575	COG2046	Belongs to the sulfate adenylyltransferase family
KU6B_RS24620	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KU6B_RS24625	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KU6B_RS24630	COG3454	Phosphonate metabolism
KU6B_RS24660	COG0489	protein tyrosine kinase activity
KU6B_RS24660	COG2151	metal-sulfur cluster biosynthetic enzyme
KU6B_RS24665	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KU6B_RS24670	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KU6B_RS24675	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KU6B_RS24680	COG0356	it plays a direct role in the translocation of protons across the membrane
KU6B_RS24705	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KU6B_RS24715	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KU6B_RS24750	COG0228	four-way junction DNA binding
KU6B_RS24755	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KU6B_RS24765	COG0336	Belongs to the RNA methyltransferase TrmD family
KU6B_RS24785	COG0335	large ribosomal subunit rRNA binding
KU6B_RS24790	COG0254	rRNA binding
KU6B_RS24810	COG1115	amino acid carrier protein
KU6B_RS24825	COG0659	secondary active sulfate transmembrane transporter activity
KU6B_RS24830	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KU6B_RS24840	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KU6B_RS24855	COG2050	protein possibly involved in aromatic compounds catabolism
KU6B_RS24870	COG0791	NLP P60 protein
KU6B_RS24885	COG0288	reversible hydration of carbon dioxide
KU6B_RS24905	COG1086	Polysaccharide biosynthesis protein
KU6B_RS24910	COG1611	Belongs to the LOG family
KU6B_RS24915	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KU6B_RS24920	COG2171	N-acyltransferase activity
KU6B_RS24930	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KU6B_RS24945	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KU6B_RS24955	COG0557	exoribonuclease II activity
KU6B_RS24980	COG1051	belongs to the nudix hydrolase family
KU6B_RS24985	COG0793	Belongs to the peptidase S41A family
KU6B_RS24995	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KU6B_RS25005	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KU6B_RS25015	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KU6B_RS25020	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KU6B_RS25040	COG0346	lactoylglutathione lyase activity
KU6B_RS25060	COG1872	DUF167
KU6B_RS25105	COG1940	carbohydrate kinase activity
KU6B_RS25125	COG0058	SHG alpha-glucan phosphorylase activity
KU6B_RS25130	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KU6B_RS25135	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KU6B_RS25140	COG0297	glycogen (starch) synthase activity
KU6B_RS25150	COG1640	4-alpha-glucanotransferase
KU6B_RS25155	COG0033	Phosphoglucomutase
KU6B_RS25165	COG0779	Required for maturation of 30S ribosomal subunits
KU6B_RS25180	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KU6B_RS25185	COG0494	nUDIX hydrolase
KU6B_RS25190	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KU6B_RS25195	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KU6B_RS25200	COG0653	protein targeting
KU6B_RS25215	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KU6B_RS25220	COG2003	Belongs to the UPF0758 family
KU6B_RS25230	COG0443	Heat shock 70 kDa protein
KU6B_RS25270	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KU6B_RS25295	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KU6B_RS25305	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KU6B_RS25310	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KU6B_RS25315	COG1137	ATPase activity
KU6B_RS25340	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
KU6B_RS25355	COG2885	chlorophyll binding
KU6B_RS25360	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KU6B_RS25370	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KU6B_RS25375	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KU6B_RS25395	COG1272	protein, Hemolysin III
KU6B_RS25400	COG1741	Belongs to the pirin family
KU6B_RS25410	COG1131	(ABC) transporter
KU6B_RS25430	COG0698	ribose 5-phosphate isomerase
KU6B_RS25440	COG0714	Associated with various cellular activities
KU6B_RS25475	COG0277	FAD linked oxidase domain protein
KU6B_RS25480	COG0277	FAD linked oxidase domain protein
KU6B_RS25490	COG0247	lactate metabolic process
KU6B_RS25500	COG0071	Belongs to the small heat shock protein (HSP20) family
KU6B_RS25535	COG1012	belongs to the aldehyde dehydrogenase family
KU6B_RS25550	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KU6B_RS25585	COG0437	4 iron, 4 sulfur cluster binding
KU6B_RS25595	COG0280	phosphate acetyltransferase
KU6B_RS25600	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KU6B_RS25605	COG0028	Belongs to the TPP enzyme family
KU6B_RS25655	COG4221	oxidoreductase activity
KU6B_RS25675	COG0438	transferase activity, transferring glycosyl groups
KU6B_RS25675	COG0297	glycogen (starch) synthase activity
KU6B_RS25685	COG0673	inositol 2-dehydrogenase activity
KU6B_RS25690	COG0489	protein tyrosine kinase activity
KU6B_RS25730	COG0438	transferase activity, transferring glycosyl groups
KU6B_RS25750	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KU6B_RS25760	COG0405	Gamma-glutamyltransferase
KU6B_RS25765	COG2824	Alkylphosphonate utilization operon protein PhnA
KU6B_RS25785	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KU6B_RS25790	COG0517	IMP dehydrogenase activity
KU6B_RS25790	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
KU6B_RS25795	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
KU6B_RS25800	COG2877	3-deoxy-8-phosphooctulonate synthase activity
KU6B_RS25805	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KU6B_RS25880	COG3474	cytochrome
KU6B_RS25915	COG1288	antiporter activity
KU6B_RS25935	COG4999	Histidine kinase
KU6B_RS25935	COG2205	protein histidine kinase activity
KU6B_RS25935	COG3850	Histidine kinase
KU6B_RS25935	COG3437	response regulator, receiver
KU6B_RS25945	COG3051	citrate lyase alpha subunit
KU6B_RS25950	COG0678	peroxiredoxin activity
KU6B_RS25965	COG0625	glutathione transferase activity
KU6B_RS25970	COG0625	glutathione transferase activity
KU6B_RS25995	COG3960	tartronate-semialdehyde synthase activity
KU6B_RS26000	COG2828	Protein conserved in bacteria
KU6B_RS26005	COG0473	3-isopropylmalate dehydrogenase activity
KU6B_RS26025	COG0642	Histidine kinase
KU6B_RS26030	COG0405	Gamma-glutamyltransferase
KU6B_RS26040	COG1802	Transcriptional regulator
KU6B_RS26050	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KU6B_RS26055	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KU6B_RS26090	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
KU6B_RS26130	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
KU6B_RS26135	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
KU6B_RS26145	COG0583	DNA-binding transcription factor activity
KU6B_RS26150	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
KU6B_RS26170	COG0802	atpase or kinase
KU6B_RS26175	COG3178	'Phosphotransferase
KU6B_RS26180	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KU6B_RS26190	COG1074	ATP-dependent DNA helicase activity
KU6B_RS26200	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KU6B_RS26210	COG1597	lipid kinase activity
KU6B_RS26215	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KU6B_RS26220	COG0747	negative chemotaxis
KU6B_RS26230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KU6B_RS26235	COG0601	transmembrane transport
KU6B_RS26245	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KU6B_RS26270	COG2226	methyltransferase
KU6B_RS26295	COG3034	peptidoglycan biosynthetic process
KU6B_RS26320	COG1132	(ABC) transporter
KU6B_RS26335	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KU6B_RS26340	COG0494	nUDIX hydrolase
KU6B_RS26345	COG0745	RESPONSE REGULATOR receiver
KU6B_RS26360	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KU6B_RS26370	COG0137	argininosuccinate synthase activity
KU6B_RS26385	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KU6B_RS26405	COG0280	phosphate acetyltransferase
KU6B_RS26405	COG0281	malic enzyme
KU6B_RS26415	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KU6B_RS26420	COG1420	regulation of RNA biosynthetic process
KU6B_RS26425	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KU6B_RS26430	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KU6B_RS26435	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KU6B_RS26455	COG0445	tRNA wobble uridine modification
KU6B_RS26460	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KU6B_RS26465	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KU6B_RS26470	COG0424	maF-like protein
KU6B_RS26475	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KU6B_RS26480	COG0237	dephospho-CoA kinase activity
KU6B_RS26485	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KU6B_RS26490	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
KU6B_RS26495	COG3030	protein affecting phage T7 exclusion by the F plasmid
KU6B_RS26510	COG2840	Smr protein MutS2
KU6B_RS26530	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KU6B_RS26540	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KU6B_RS26550	COG1749	Flagellar hook protein flgE
KU6B_RS26565	COG1706	bacterial-type flagellum-dependent cell motility
KU6B_RS26570	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KU6B_RS26580	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KU6B_RS26590	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KU6B_RS26605	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
KU6B_RS26615	COG4786	Flagellar basal body rod
KU6B_RS26620	COG4786	Flagellar basal body rod
KU6B_RS26625	COG1987	bacterial-type flagellum assembly
KU6B_RS26635	COG1558	bacterial-type flagellum-dependent cell motility
KU6B_RS26655	COG5443	negative regulation of bacterial-type flagellum assembly
KU6B_RS26690	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
KU6B_RS26705	COG2226	methyltransferase
KU6B_RS26710	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KU6B_RS26720	COG0268	Binds directly to 16S ribosomal RNA
KU6B_RS26735	COG1653	transport
KU6B_RS26740	COG1175	transmembrane transport
KU6B_RS26745	COG0395	ABC-type sugar transport system, permease component
KU6B_RS26750	COG3842	ATPase activity
KU6B_RS26755	COG4948	Mandelate Racemase Muconate Lactonizing
KU6B_RS26765	COG0508	dehydrogenase complex catalyzes the overall conversion of
KU6B_RS26770	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
KU6B_RS26795	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KU6B_RS26800	COG0402	S-adenosylhomocysteine deaminase activity
KU6B_RS26805	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KU6B_RS26810	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KU6B_RS26815	COG2249	NAD(P)H dehydrogenase (quinone) activity
KU6B_RS26845	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KU6B_RS26850	COG4597	amino acid ABC transporter
KU6B_RS26855	COG0765	amino acid transport
KU6B_RS26860	COG1126	abc transporter atp-binding protein
KU6B_RS26870	COG3119	arylsulfatase activity
KU6B_RS26875	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KU6B_RS26880	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KU6B_RS26890	COG1012	belongs to the aldehyde dehydrogenase family
KU6B_RS26900	COG1028	Short-chain dehydrogenase reductase Sdr
KU6B_RS26905	COG3938	Belongs to the proline racemase family
KU6B_RS26920	COG0436	Aminotransferase
KU6B_RS26925	COG1012	belongs to the aldehyde dehydrogenase family
KU6B_RS26935	COG5383	Protein conserved in bacteria
KU6B_RS26955	COG3119	arylsulfatase activity
KU6B_RS26970	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KU6B_RS26975	COG0277	FAD linked oxidase domain protein
KU6B_RS27020	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KU6B_RS27030	COG2986	histidine ammonia-lyase
KU6B_RS27035	COG1228	amidohydrolase
KU6B_RS27080	COG0318	PFAM AMP-dependent synthetase and ligase
KU6B_RS27085	COG1028	Short-chain dehydrogenase reductase Sdr
KU6B_RS27090	COG2030	dehydratase
KU6B_RS27105	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
KU6B_RS27110	COG2358	TRAP transporter, solute receptor (TAXI family
KU6B_RS27135	COG3609	addiction module antidote protein, CC2985 family
KU6B_RS27140	COG0535	radical SAM domain protein
KU6B_RS27145	COG0535	radical SAM domain protein
KU6B_RS27150	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
KU6B_RS27155	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KU6B_RS27165	COG0745	RESPONSE REGULATOR receiver
KU6B_RS27170	COG5002	protein histidine kinase activity
KU6B_RS27170	COG3850	Histidine kinase
KU6B_RS27270	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
KU6B_RS27275	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
KU6B_RS27310	COG2205	protein histidine kinase activity
KU6B_RS27325	COG3791	Glutathione-dependent formaldehyde-activating
KU6B_RS27340	COG1192	Involved in chromosome partitioning
KU6B_RS27345	COG1475	DNA binding
KU6B_RS27350	COG1414	Transcriptional regulator
KU6B_RS27380	COG3311	Transcriptional regulator
KU6B_RS27395	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KU6B_RS27440	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KU6B_RS27455	COG0508	dehydrogenase complex catalyzes the overall conversion of
KU6B_RS27460	COG0095	Lipoate-protein ligase
KU6B_RS27480	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KU6B_RS27490	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
KU6B_RS27505	COG2022	thiamine diphosphate biosynthetic process
KU6B_RS27515	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KU6B_RS27520	COG0351	phosphomethylpyrimidine kinase
KU6B_RS27625	COG2003	Belongs to the UPF0758 family
KU6B_RS27665	COG4974	Belongs to the 'phage' integrase family
KU6B_RS27685	COG1733	regulation of RNA biosynthetic process
KU6B_RS27700	COG5507	3-demethylubiquinone-9 3-methyltransferase
KU6B_RS27705	COG0625	glutathione transferase activity
KU6B_RS27710	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KU6B_RS27725	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KU6B_RS27745	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KU6B_RS27760	COG1309	transcriptional regulator
KU6B_RS27785	COG5642	Protein of unknown function (DUF2384)
KU6B_RS27805	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
KU6B_RS27810	COG2948	multi-organism process
KU6B_RS27830	COG0741	lytic transglycosylase activity
KU6B_RS27830	COG1196	nuclear chromosome segregation
KU6B_RS27830	COG0739	heme binding
KU6B_RS27895	COG0318	PFAM AMP-dependent synthetase and ligase
KU6B_RS27910	COG1120	ATPase activity
KU6B_RS27915	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KU6B_RS27920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KU6B_RS27925	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
KU6B_RS27960	COG2910	NAD(P)H-binding
KU6B_RS27965	COG1733	regulation of RNA biosynthetic process
KU6B_RS27985	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KU6B_RS27990	COG0569	domain protein
KU6B_RS27995	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KU6B_RS28000	COG2814	Major facilitator Superfamily
KU6B_RS28005	COG1120	ATPase activity
KU6B_RS28010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KU6B_RS28015	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KU6B_RS28020	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KU6B_RS28045	COG2963	transposase activity
KU6B_RS28050	COG0683	leucine binding
KU6B_RS28065	COG0559	Belongs to the binding-protein-dependent transport system permease family
KU6B_RS28075	COG0596	Alpha beta hydrolase
KU6B_RS28090	COG0318	PFAM AMP-dependent synthetase and ligase
KU6B_RS28100	COG1309	transcriptional regulator
KU6B_RS28110	COG0419	ATPase involved in DNA repair
KU6B_RS28125	COG0583	DNA-binding transcription factor activity
KU6B_RS28185	COG3451	type IV secretory pathway VirB4
KU6B_RS28195	COG1196	nuclear chromosome segregation
KU6B_RS28195	COG0741	lytic transglycosylase activity
KU6B_RS28195	COG0739	heme binding
KU6B_RS28215	COG2948	multi-organism process
KU6B_RS28220	COG4962	Type ii secretion system protein e
KU6B_RS28240	COG1230	cation diffusion facilitator family transporter
KU6B_RS28290	COG0398	Pfam SNARE associated Golgi protein
KU6B_RS28310	COG0745	RESPONSE REGULATOR receiver
KU6B_RS28325	COG1138	Cytochrome C-type biogenesis protein
KU6B_RS28330	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KU6B_RS28335	COG3088	subunit of a heme lyase
KU6B_RS28340	COG4235	cytochrome complex assembly
KU6B_RS28395	COG2010	Cytochrome c
KU6B_RS28400	COG2132	Multicopper oxidase
KU6B_RS28405	COG2010	Cytochrome c
KU6B_RS28410	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KU6B_RS28410	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KU6B_RS28465	COG2132	Multicopper oxidase
KU6B_RS28475	COG3177	Filamentation induced by cAMP protein fic
KU6B_RS28495	COG3831	ATPase activity
KU6B_RS28520	COG4453	Protein conserved in bacteria
KU6B_RS28625	COG1414	Transcriptional regulator
KU6B_RS28630	COG1475	DNA binding
KU6B_RS28635	COG1192	Involved in chromosome partitioning
KU6B_RS28640	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KU6B_RS28655	COG0745	RESPONSE REGULATOR receiver
KU6B_RS28680	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KU6B_RS28700	COG1475	DNA binding
KU6B_RS28760	COG1192	Involved in chromosome partitioning
KU6B_RS28770	COG1414	Transcriptional regulator
KU6B_RS28785	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KU6B_RS28790	COG5290	Psort location Cytoplasmic, score
KU6B_RS28795	COG2433	Pfam Transposase IS66
KU6B_RS28800	COG3436	PFAM IS66 Orf2 family protein
KU6B_RS28805	COG4974	Belongs to the 'phage' integrase family
KU6B_RS28810	COG4974	Belongs to the 'phage' integrase family
KU6B_RS28815	COG4974	Belongs to the 'phage' integrase family
KU6B_RS28855	COG3505	Type IV secretory pathway VirD4
KU6B_RS28865	COG3831	ATPase activity
KU6B_RS28875	COG1204	response to ionizing radiation
KU6B_RS28890	COG2948	multi-organism process
KU6B_RS28900	COG3736	Type IV secretory pathway, component VirB8
KU6B_RS28920	COG0741	lytic transglycosylase activity
KU6B_RS28920	COG0739	heme binding
KU6B_RS28920	COG1196	nuclear chromosome segregation
KU6B_RS28930	COG3451	type IV secretory pathway VirB4
KU6B_RS28945	COG0741	lytic transglycosylase activity
KU6B_RS28945	COG1196	nuclear chromosome segregation
KU6B_RS28945	COG0739	heme binding
KU6B_RS28970	COG0183	Belongs to the thiolase family
KU6B_RS29000	COG3547	Transposase (IS116 IS110 IS902 family)
KU6B_RS29010	COG1024	Enoyl-CoA hydratase
KU6B_RS29010	COG1250	3-hydroxyacyl-CoA dehydrogenase
KU6B_RS29035	COG1804	L-carnitine dehydratase bile acid-inducible protein F