locus-tag	class	description
JRU67_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JRU67_RS00010	COG0592	DNA-directed DNA polymerase activity
JRU67_RS00020	COG4152	abc transporter atp-binding protein
JRU67_RS00025	COG1668	transmembrane transport
JRU67_RS00030	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JRU67_RS00035	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
JRU67_RS00040	COG2501	S4 domain
JRU67_RS00045	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JRU67_RS00055	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JRU67_RS00060	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
JRU67_RS00070	COG2986	histidine ammonia-lyase
JRU67_RS00080	COG1228	amidohydrolase
JRU67_RS00085	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JRU67_RS00105	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JRU67_RS00115	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
JRU67_RS00120	COG0359	binds to the 23S rRNA
JRU67_RS00125	COG0305	Participates in initiation and elongation during chromosome replication
JRU67_RS00130	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JRU67_RS00140	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JRU67_RS00160	COG5002	protein histidine kinase activity
JRU67_RS00175	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
JRU67_RS00180	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
JRU67_RS00260	COG0438	transferase activity, transferring glycosyl groups
JRU67_RS00270	COG0456	acetyltransferase
JRU67_RS00285	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JRU67_RS00300	COG0584	glycerophosphoryl diester phosphodiesterase
JRU67_RS00305	COG2030	dehydratase
JRU67_RS00330	COG1940	carbohydrate kinase activity
JRU67_RS00330	COG1846	Transcriptional regulator
JRU67_RS00340	COG2210	Belongs to the sulfur carrier protein TusA family
JRU67_RS00345	COG1937	Protein conserved in bacteria
JRU67_RS00350	COG0730	response to heat
JRU67_RS00385	COG2003	Belongs to the UPF0758 family
JRU67_RS00435	COG2226	methyltransferase
JRU67_RS00470	COG1695	Transcriptional regulator
JRU67_RS00490	COG2217	Heavy metal translocating P-type atpase
JRU67_RS00495	COG1388	LysM domain
JRU67_RS00505	COG0702	epimerase
JRU67_RS00510	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
JRU67_RS00545	COG0415	Belongs to the DNA photolyase family
JRU67_RS00560	COG0730	response to heat
JRU67_RS00565	COG1937	Protein conserved in bacteria
JRU67_RS00570	COG2210	Belongs to the sulfur carrier protein TusA family
JRU67_RS00575	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JRU67_RS00585	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JRU67_RS00590	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JRU67_RS00600	COG0446	pyridine nucleotide-disulphide oxidoreductase
JRU67_RS00620	COG0640	Transcriptional regulator
JRU67_RS00635	COG1486	melibiose metabolic process
JRU67_RS00640	COG2211	Major facilitator Superfamily
JRU67_RS00660	COG1063	alcohol dehydrogenase
JRU67_RS00680	COG1595	DNA-templated transcription, initiation
JRU67_RS00705	COG0415	Belongs to the DNA photolyase family
JRU67_RS00715	COG1064	alcohol dehydrogenase
JRU67_RS00725	COG2814	Major facilitator Superfamily
JRU67_RS00760	COG0642	Histidine kinase
JRU67_RS00775	COG1288	antiporter activity
JRU67_RS00780	COG3711	transcriptional antiterminator
JRU67_RS00785	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JRU67_RS00785	COG1263	PTS System
JRU67_RS00790	COG2723	6-phospho-beta-galactosidase activity
JRU67_RS00800	COG2807	transmembrane transport
JRU67_RS00805	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
JRU67_RS00825	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JRU67_RS00830	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JRU67_RS00840	COG1609	Transcriptional regulator
JRU67_RS00845	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JRU67_RS00850	COG2610	gluconate transmembrane transporter activity
JRU67_RS00860	COG0454	-acetyltransferase
JRU67_RS00895	COG3290	protein histidine kinase activity
JRU67_RS00900	COG4565	transcriptional regulatory protein
JRU67_RS00920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JRU67_RS00925	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JRU67_RS00930	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JRU67_RS00935	COG0019	diaminopimelate decarboxylase activity
JRU67_RS00945	COG4264	IucA IucC family
JRU67_RS00950	COG4264	IucA IucC family
JRU67_RS00960	COG0702	epimerase
JRU67_RS00965	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
JRU67_RS00985	COG2801	Transposase and inactivated derivatives
JRU67_RS00995	COG1114	Component of the transport system for branched-chain amino acids
JRU67_RS01005	COG0183	Belongs to the thiolase family
JRU67_RS01010	COG3425	synthase
JRU67_RS01020	COG0477	Major facilitator Superfamily
JRU67_RS01025	COG0584	glycerophosphoryl diester phosphodiesterase
JRU67_RS01035	COG1846	Transcriptional regulator
JRU67_RS01050	COG0531	amino acid
JRU67_RS01055	COG1940	carbohydrate kinase activity
JRU67_RS01055	COG1846	Transcriptional regulator
JRU67_RS01060	COG2115	Belongs to the xylose isomerase family
JRU67_RS01065	COG1070	Carbohydrate kinase
JRU67_RS01070	COG0477	Major facilitator Superfamily
JRU67_RS01070	COG2814	Major facilitator Superfamily
JRU67_RS01080	COG1028	Short-chain dehydrogenase reductase Sdr
JRU67_RS01085	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
JRU67_RS01090	COG0157	Belongs to the NadC ModD family
JRU67_RS01095	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
JRU67_RS01100	COG1104	cysteine desulfurase activity
JRU67_RS01105	COG1827	regulation of RNA biosynthetic process
JRU67_RS01115	COG2318	DinB family
JRU67_RS01120	COG2851	Citrate transporter
JRU67_RS01125	COG1054	Belongs to the UPF0176 family
JRU67_RS01145	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JRU67_RS01165	COG0083	homoserine kinase activity
JRU67_RS01170	COG3386	PFAM SMP-30 Gluconolaconase
JRU67_RS01175	COG1304	FMN binding
JRU67_RS01195	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JRU67_RS01200	COG1028	Short-chain dehydrogenase reductase Sdr
JRU67_RS01210	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JRU67_RS01210	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JRU67_RS01210	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JRU67_RS01215	COG3711	transcriptional antiterminator
JRU67_RS01215	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JRU67_RS01225	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JRU67_RS01240	COG0579	oxidoreductase
JRU67_RS01250	COG0318	PFAM AMP-dependent synthetase and ligase
JRU67_RS01255	COG1960	acyl-CoA dehydrogenase activity
JRU67_RS01260	COG1024	Enoyl-CoA hydratase
JRU67_RS01260	COG1250	3-hydroxyacyl-CoA dehydrogenase
JRU67_RS01265	COG0183	Belongs to the thiolase family
JRU67_RS01270	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JRU67_RS01275	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JRU67_RS01280	COG3002	Belongs to the UPF0753 family
JRU67_RS01285	COG0288	reversible hydration of carbon dioxide
JRU67_RS01290	COG5609	conserved protein (DUF2294)
JRU67_RS01295	COG1283	sodium-dependent phosphate transmembrane transporter activity
JRU67_RS01300	COG0673	inositol 2-dehydrogenase activity
JRU67_RS01310	COG0673	inositol 2-dehydrogenase activity
JRU67_RS01335	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
JRU67_RS01350	COG0733	neurotransmitter:sodium symporter activity
JRU67_RS01355	COG0583	DNA-binding transcription factor activity
JRU67_RS01360	COG1380	Effector of murein hydrolase LrgA
JRU67_RS01370	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JRU67_RS01375	COG0175	sulfate reduction
JRU67_RS01380	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JRU67_RS01385	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JRU67_RS01405	COG0730	response to heat
JRU67_RS01410	COG2046	Belongs to the sulfate adenylyltransferase family
JRU67_RS01415	COG0529	Catalyzes the synthesis of activated sulfate
JRU67_RS01420	COG1510	regulation of RNA biosynthetic process
JRU67_RS01425	COG1012	belongs to the aldehyde dehydrogenase family
JRU67_RS01445	COG0659	secondary active sulfate transmembrane transporter activity
JRU67_RS01455	COG1621	beta-fructofuranosidase activity
JRU67_RS01465	COG3588	fructose-bisphosphate aldolase
JRU67_RS01475	COG2190	(PTS) system
JRU67_RS01475	COG1263	PTS System
JRU67_RS01475	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JRU67_RS01485	COG1486	melibiose metabolic process
JRU67_RS01490	COG2188	Transcriptional regulator
JRU67_RS01495	COG1247	-acetyltransferase
JRU67_RS01500	COG0668	transmembrane transport
JRU67_RS01525	COG2851	Citrate transporter
JRU67_RS01530	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
JRU67_RS01545	COG3328	transposase activity
JRU67_RS01550	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
JRU67_RS01560	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
JRU67_RS01565	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JRU67_RS01570	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JRU67_RS01580	COG0477	Major facilitator Superfamily
JRU67_RS01585	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JRU67_RS01605	COG2205	protein histidine kinase activity
JRU67_RS01610	COG0745	RESPONSE REGULATOR receiver
JRU67_RS01615	COG2311	Membrane
JRU67_RS01630	COG3961	Belongs to the TPP enzyme family
JRU67_RS01645	COG1063	alcohol dehydrogenase
JRU67_RS01655	COG1063	alcohol dehydrogenase
JRU67_RS01660	COG3775	system Galactitol-specific IIC component
JRU67_RS01665	COG3414	Phosphotransferase system galactitol-specific IIB component
JRU67_RS01680	COG0531	amino acid
JRU67_RS01695	COG1464	Belongs to the NlpA lipoprotein family
JRU67_RS01700	COG2271	Major facilitator Superfamily
JRU67_RS01765	COG0531	amino acid
JRU67_RS01770	COG2130	NADP-dependent
JRU67_RS01785	COG2188	Transcriptional regulator
JRU67_RS01790	COG2222	sugar isomerase
JRU67_RS01800	COG3684	Belongs to the aldolase LacD family
JRU67_RS01810	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JRU67_RS01815	COG3715	PTS system
JRU67_RS01820	COG3716	PTS system mannose fructose sorbose family IID component
JRU67_RS01845	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
JRU67_RS01850	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JRU67_RS01855	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
JRU67_RS01875	COG1316	TRANSCRIPTIONal
JRU67_RS01885	COG3001	Fructosamine kinase
JRU67_RS01890	COG1396	sequence-specific DNA binding
JRU67_RS01895	COG2807	transmembrane transport
JRU67_RS01900	COG1113	amino acid transport
JRU67_RS01910	COG3620	sequence-specific DNA binding
JRU67_RS01930	COG0488	(ABC) transporter
JRU67_RS01945	COG2084	Dehydrogenase
JRU67_RS01970	COG4336	lyase activity
JRU67_RS01975	COG3275	phosphorelay sensor kinase activity
JRU67_RS01980	COG3279	Response regulator of the LytR AlgR family
JRU67_RS01985	COG1380	Effector of murein hydrolase LrgA
JRU67_RS01990	COG1346	cytolysis
JRU67_RS02000	COG3844	kynureninase activity
JRU67_RS02005	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JRU67_RS02015	COG2188	Transcriptional regulator
JRU67_RS02020	COG2723	6-phospho-beta-galactosidase activity
JRU67_RS02040	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
JRU67_RS02045	COG1280	lysine exporter protein (LysE YggA)
JRU67_RS02050	COG1132	(ABC) transporter
JRU67_RS02055	COG1132	(ABC) transporter
JRU67_RS02065	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
JRU67_RS02070	COG3189	MarR family transcriptional regulator
JRU67_RS02080	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JRU67_RS02085	COG2022	thiamine diphosphate biosynthetic process
JRU67_RS02095	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JRU67_RS02100	COG0352	thiamine-phosphate diphosphorylase activity
JRU67_RS02110	COG3279	Response regulator of the LytR AlgR family
JRU67_RS02120	COG1733	regulation of RNA biosynthetic process
JRU67_RS02125	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
JRU67_RS02145	COG1380	Effector of murein hydrolase LrgA
JRU67_RS02155	COG1278	Cold shock
JRU67_RS02165	COG0833	amino acid
JRU67_RS02170	COG2040	homocysteine
JRU67_RS02175	COG1012	belongs to the aldehyde dehydrogenase family
JRU67_RS02180	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JRU67_RS02205	COG0656	L-ascorbic acid biosynthetic process
JRU67_RS02210	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
JRU67_RS02215	COG3759	membrane
JRU67_RS02220	COG2409	Drug exporters of the RND superfamily
JRU67_RS02230	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
JRU67_RS02235	COG1263	PTS System
JRU67_RS02235	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JRU67_RS02240	COG1737	Transcriptional regulator
JRU67_RS02250	COG1316	TRANSCRIPTIONal
JRU67_RS02260	COG2207	Transcriptional regulator
JRU67_RS02280	COG0582	viral genome integration into host DNA
JRU67_RS02285	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JRU67_RS02285	COG2111	Na H antiporter
JRU67_RS02290	COG2111	Na H antiporter
JRU67_RS02305	COG1863	multisubunit Na H antiporter MnhE subunit
JRU67_RS02310	COG2212	antiporter activity
JRU67_RS02315	COG1320	monovalent cation:proton antiporter activity
JRU67_RS02325	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JRU67_RS02335	COG1321	iron dependent repressor
JRU67_RS02345	COG1686	Belongs to the peptidase S11 family
JRU67_RS02350	COG1132	(ABC) transporter
JRU67_RS02355	COG1620	l-lactate permease
JRU67_RS02360	COG0039	L-malate dehydrogenase activity
JRU67_RS02375	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JRU67_RS02380	COG1120	ATPase activity
JRU67_RS02385	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JRU67_RS02390	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JRU67_RS02405	COG1302	Protein conserved in bacteria
JRU67_RS02420	COG2801	Transposase and inactivated derivatives
JRU67_RS02425	COG2814	Major facilitator Superfamily
JRU67_RS02430	COG3314	Sporulation integral membrane protein YlbJ
JRU67_RS02435	COG2801	Transposase and inactivated derivatives
JRU67_RS02450	COG2329	Antibiotic biosynthesis monooxygenase
JRU67_RS02455	COG0300	oxidoreductase activity
JRU67_RS02465	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JRU67_RS02470	COG2962	Rard protein
JRU67_RS02485	COG1988	membrane-bound metal-dependent
JRU67_RS02500	COG1272	protein, Hemolysin III
JRU67_RS02515	COG1574	metal-dependent hydrolase with the TIM-barrel fold
JRU67_RS02530	COG2814	Major facilitator Superfamily
JRU67_RS02535	COG0489	protein tyrosine kinase activity
JRU67_RS02540	COG2194	sulfuric ester hydrolase activity
JRU67_RS02605	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JRU67_RS02615	COG1937	Protein conserved in bacteria
JRU67_RS02620	COG2217	Heavy metal translocating P-type atpase
JRU67_RS02625	COG0586	Pfam SNARE associated Golgi protein
JRU67_RS02630	COG0456	acetyltransferase
JRU67_RS02640	COG2514	catechol 2,3-dioxygenase activity
JRU67_RS02670	COG0702	epimerase
JRU67_RS02685	COG0640	Transcriptional regulator
JRU67_RS02700	COG0477	Major facilitator Superfamily
JRU67_RS02720	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JRU67_RS02730	COG2205	protein histidine kinase activity
JRU67_RS02735	COG1136	(ABC) transporter
JRU67_RS02740	COG0577	efflux transmembrane transporter activity
JRU67_RS02745	COG1392	Phosphate transport regulator
JRU67_RS02750	COG0306	phosphate transporter
JRU67_RS02755	COG3942	CHAP domain
JRU67_RS02755	COG1388	LysM domain
JRU67_RS02760	COG0670	Belongs to the BI1 family
JRU67_RS02765	COG0217	transcriptional regulatory protein
JRU67_RS02775	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JRU67_RS02795	COG1566	PFAM secretion protein HlyD family protein
JRU67_RS02800	COG2814	Major facilitator Superfamily
JRU67_RS02815	COG0583	DNA-binding transcription factor activity
JRU67_RS02820	COG2258	MOSC domain
JRU67_RS02830	COG2839	Protein conserved in bacteria
JRU67_RS02840	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JRU67_RS02850	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JRU67_RS02855	COG1447	Phosphotransferase system cellobiose-specific component IIA
JRU67_RS02860	COG4221	oxidoreductase activity
JRU67_RS02865	COG0788	formyltetrahydrofolate deformylase activity
JRU67_RS02870	COG0598	Magnesium transport protein CorA
JRU67_RS02875	COG1940	carbohydrate kinase activity
JRU67_RS02885	COG3328	transposase activity
JRU67_RS02895	COG0778	Nitroreductase
JRU67_RS02905	COG2814	Major facilitator Superfamily
JRU67_RS02910	COG1733	regulation of RNA biosynthetic process
JRU67_RS02915	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
JRU67_RS02940	COG1757	Na H antiporter
JRU67_RS02945	COG0004	ammonium transporteR
JRU67_RS02950	COG1473	amidohydrolase
JRU67_RS02960	COG2814	Major facilitator Superfamily
JRU67_RS02965	COG0753	catalase activity
JRU67_RS02980	COG3048	D-serine ammonia-lyase activity
JRU67_RS02990	COG1966	Carbon starvation protein
JRU67_RS02995	COG3383	formate dehydrogenase (NAD+) activity
JRU67_RS03015	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JRU67_RS03025	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JRU67_RS03030	COG2011	ABC-type metal ion transport system permease component
JRU67_RS03035	COG1464	Belongs to the NlpA lipoprotein family
JRU67_RS03050	COG3942	CHAP domain
JRU67_RS03055	COG1757	Na H antiporter
JRU67_RS03060	COG3942	CHAP domain
JRU67_RS03125	COG1131	(ABC) transporter
JRU67_RS03130	COG1823	symporter activity
JRU67_RS03135	COG1960	acyl-CoA dehydrogenase activity
JRU67_RS03140	COG0697	spore germination
JRU67_RS03145	COG2832	Protein of unknown function (DUF454)
JRU67_RS03150	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JRU67_RS03170	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JRU67_RS03180	COG2186	Transcriptional regulator
JRU67_RS03185	COG2186	Transcriptional regulator
JRU67_RS03195	COG1268	BioY protein
JRU67_RS03205	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
JRU67_RS03210	COG3383	formate dehydrogenase (NAD+) activity
JRU67_RS03220	COG4149	molybdate abc transporter
JRU67_RS03225	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
JRU67_RS03235	COG1140	nitrate reductase beta subunit
JRU67_RS03240	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
JRU67_RS03245	COG2181	nitrate reductase activity
JRU67_RS03255	COG4585	Histidine kinase
JRU67_RS03260	COG2197	response regulator
JRU67_RS03265	COG2223	nitrite transmembrane transporter activity
JRU67_RS03270	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JRU67_RS03275	COG0521	Mo-molybdopterin cofactor biosynthetic process
JRU67_RS03280	COG0315	cyclic pyranopterin monophosphate synthase activity
JRU67_RS03285	COG0303	'Molybdopterin
JRU67_RS03290	COG1763	Mo-molybdopterin cofactor biosynthetic process
JRU67_RS03305	COG0746	molybdenum cofactor guanylyltransferase activity
JRU67_RS03310	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JRU67_RS03315	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JRU67_RS03320	COG2814	Major facilitator Superfamily
JRU67_RS03330	COG2348	transferase activity, transferring amino-acyl groups
JRU67_RS03335	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JRU67_RS03340	COG0436	Aminotransferase
JRU67_RS03355	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JRU67_RS03370	COG4975	Glucose uptake
JRU67_RS03385	COG2252	PERMEase
JRU67_RS03395	COG0051	transcription antitermination factor activity, RNA binding
JRU67_RS03400	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JRU67_RS03405	COG0088	Forms part of the polypeptide exit tunnel
JRU67_RS03410	COG0089	rRNA binding
JRU67_RS03415	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JRU67_RS03420	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JRU67_RS03425	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
JRU67_RS03430	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JRU67_RS03435	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
JRU67_RS03440	COG0255	Belongs to the universal ribosomal protein uL29 family
JRU67_RS03450	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JRU67_RS03455	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
JRU67_RS03460	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
JRU67_RS03465	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JRU67_RS03470	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JRU67_RS03475	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JRU67_RS03480	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
JRU67_RS03485	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JRU67_RS03490	COG1841	ribosomal large subunit assembly
JRU67_RS03500	COG0201	protein transport
JRU67_RS03515	COG0257	Belongs to the bacterial ribosomal protein bL36 family
JRU67_RS03520	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JRU67_RS03530	COG0202	RNA polymerase activity
JRU67_RS03535	COG0203	ribosomal protein L17
JRU67_RS03545	COG1122	ATPase activity
JRU67_RS03555	COG0101	tRNA pseudouridine synthase activity
JRU67_RS03560	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JRU67_RS03565	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
JRU67_RS03570	COG1011	Hydrolase
JRU67_RS03600	COG1132	(ABC) transporter
JRU67_RS03610	COG3655	Transcriptional regulator
JRU67_RS03615	COG0346	lactoylglutathione lyase activity
JRU67_RS03640	COG0604	alcohol dehydrogenase
JRU67_RS03650	COG1511	domain protein
JRU67_RS03660	COG3842	ATPase activity
JRU67_RS03665	COG2182	Extracellular solute-binding protein
JRU67_RS03670	COG1175	transmembrane transport
JRU67_RS03675	COG3833	ABC-type maltose transport systems, permease component
JRU67_RS03680	COG1609	Transcriptional regulator
JRU67_RS03685	COG0366	Alpha amylase catalytic
JRU67_RS03690	COG2376	Dihydroxyacetone kinase
JRU67_RS03695	COG1461	Dihydroxyacetone kinase
JRU67_RS03700	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
JRU67_RS03705	COG2186	Transcriptional regulator
JRU67_RS03710	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
JRU67_RS03715	COG1482	cell wall glycoprotein biosynthetic process
JRU67_RS03725	COG1388	LysM domain
JRU67_RS03725	COG3942	CHAP domain
JRU67_RS03735	COG1115	amino acid carrier protein
JRU67_RS03745	COG1757	Na H antiporter
JRU67_RS03755	COG1609	Transcriptional regulator
JRU67_RS03760	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JRU67_RS03765	COG1869	D-ribose catabolic process
JRU67_RS03770	COG1129	ABC transporter
JRU67_RS03775	COG1172	Belongs to the binding-protein-dependent transport system permease family
JRU67_RS03780	COG1879	ABC-type sugar transport system periplasmic component
JRU67_RS03785	COG0783	Belongs to the Dps family
JRU67_RS03790	COG0277	FAD linked oxidase domain protein
JRU67_RS03795	COG0247	lactate metabolic process
JRU67_RS03800	COG0813	purine-nucleoside phosphorylase activity
JRU67_RS03805	COG2390	Transcriptional regulator
JRU67_RS03810	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JRU67_RS03820	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
JRU67_RS03830	COG1854	S-ribosylhomocysteine lyase activity
JRU67_RS03835	COG0456	acetyltransferase
JRU67_RS03835	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
JRU67_RS03875	COG5146	pantothenate kinase activity
JRU67_RS03880	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JRU67_RS03885	COG4589	Belongs to the CDS family
JRU67_RS03915	COG3343	RNA polymerase activity
JRU67_RS03920	COG0504	CTP synthase activity
JRU67_RS03925	COG4821	SIS domain
JRU67_RS03935	COG0191	fructose-bisphosphate aldolase activity
JRU67_RS03940	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JRU67_RS03955	COG2801	Transposase and inactivated derivatives
JRU67_RS03965	COG1012	belongs to the aldehyde dehydrogenase family
JRU67_RS03970	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
JRU67_RS03975	COG0254	rRNA binding
JRU67_RS03980	COG1435	thymidine kinase activity
JRU67_RS03990	COG2890	protein-(glutamine-N5) methyltransferase activity
JRU67_RS03995	COG0009	L-threonylcarbamoyladenylate synthase
JRU67_RS04000	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JRU67_RS04005	COG0698	ribose 5-phosphate isomerase
JRU67_RS04010	COG4475	Protein of unknown function (DUF436)
JRU67_RS04015	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JRU67_RS04020	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JRU67_RS04025	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
JRU67_RS04035	COG0356	it plays a direct role in the translocation of protons across the membrane
JRU67_RS04040	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JRU67_RS04045	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JRU67_RS04050	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JRU67_RS04055	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JRU67_RS04060	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JRU67_RS04065	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JRU67_RS04090	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JRU67_RS04100	COG0629	single-stranded DNA binding
JRU67_RS04105	COG1388	LysM domain
JRU67_RS04115	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
JRU67_RS04120	COG0352	thiamine-phosphate diphosphorylase activity
JRU67_RS04125	COG0706	membrane insertase activity
JRU67_RS04130	COG1418	mRNA catabolic process
JRU67_RS04135	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JRU67_RS04145	COG0772	Belongs to the SEDS family
JRU67_RS04150	COG1181	Belongs to the D-alanine--D-alanine ligase family
JRU67_RS04155	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JRU67_RS04165	COG0513	Belongs to the DEAD box helicase family
JRU67_RS04205	COG2208	phosphoserine phosphatase activity
JRU67_RS04220	COG1191	sigma factor activity
JRU67_RS04225	COG2183	response to ionizing radiation
JRU67_RS04230	COG3091	SprT-like family
JRU67_RS04260	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JRU67_RS04270	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JRU67_RS04275	COG0473	3-isopropylmalate dehydrogenase activity
JRU67_RS04280	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JRU67_RS04285	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
JRU67_RS04295	COG0028	Belongs to the TPP enzyme family
JRU67_RS04300	COG0129	dihydroxy-acid dehydratase activity
JRU67_RS04305	COG0802	atpase or kinase
JRU67_RS04310	COG1214	PFAM Peptidase M22, glycoprotease
JRU67_RS04315	COG0456	acetyltransferase
JRU67_RS04335	COG0488	(ABC) transporter
JRU67_RS04340	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
JRU67_RS04345	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JRU67_RS04350	COG0805	protein transport
JRU67_RS04355	COG2391	methyltransferase activity
JRU67_RS04360	COG0425	Belongs to the sulfur carrier protein TusA family
JRU67_RS04365	COG1609	Transcriptional regulator
JRU67_RS04370	COG1621	beta-fructofuranosidase activity
JRU67_RS04410	COG0459	protein refolding
JRU67_RS04415	COG0582	viral genome integration into host DNA
JRU67_RS04500	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JRU67_RS04520	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JRU67_RS04525	COG1131	(ABC) transporter
JRU67_RS04540	COG1131	(ABC) transporter
JRU67_RS04555	COG1473	amidohydrolase
JRU67_RS04560	COG1802	Transcriptional regulator
JRU67_RS04565	COG1070	Carbohydrate kinase
JRU67_RS04570	COG2610	gluconate transmembrane transporter activity
JRU67_RS04575	COG2223	nitrite transmembrane transporter activity
JRU67_RS04605	COG0385	Bile acid
JRU67_RS04645	COG4512	PFAM Accessory gene regulator B
JRU67_RS04650	COG2706	6-phosphogluconolactonase activity
JRU67_RS04660	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JRU67_RS04665	COG0390	transport system, permease component
JRU67_RS04670	COG1012	belongs to the aldehyde dehydrogenase family
JRU67_RS04675	COG0673	inositol 2-dehydrogenase activity
JRU67_RS04690	COG1227	inorganic diphosphatase activity
JRU67_RS04695	COG1335	isochorismatase
JRU67_RS04710	COG0077	Prephenate dehydratase
JRU67_RS04725	COG0107	imidazoleglycerol-phosphate synthase activity
JRU67_RS04730	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
JRU67_RS04735	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
JRU67_RS04740	COG0131	Imidazoleglycerol-phosphate dehydratase
JRU67_RS04745	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JRU67_RS04750	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JRU67_RS04755	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
JRU67_RS04760	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
JRU67_RS04765	COG0477	Major facilitator Superfamily
JRU67_RS04770	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JRU67_RS04775	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
JRU67_RS04780	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
JRU67_RS04790	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JRU67_RS04795	COG4496	protein, YerC YecD
JRU67_RS04800	COG1876	peptidase activity
JRU67_RS04805	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
JRU67_RS04810	COG0210	DNA helicase
JRU67_RS04815	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JRU67_RS04820	COG4851	CamS sex pheromone cAM373 precursor
JRU67_RS04825	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JRU67_RS04830	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JRU67_RS04840	COG0154	amidase activity
JRU67_RS04845	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JRU67_RS04850	COG0433	COG0433 Predicted ATPase
JRU67_RS04855	COG1597	lipid kinase activity
JRU67_RS04875	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JRU67_RS04890	COG1528	Iron-storage protein
JRU67_RS04905	COG4129	membrane
JRU67_RS04910	COG0024	Methionine aminopeptidase
JRU67_RS04930	COG2197	response regulator
JRU67_RS04935	COG0288	reversible hydration of carbon dioxide
JRU67_RS04940	COG1295	ribonuclease BN
JRU67_RS04955	COG4840	Belongs to the UPF0435 family
JRU67_RS04960	COG2309	aminopeptidase activity
JRU67_RS04970	COG1607	acyl-coa hydrolase
JRU67_RS04975	COG0535	radical SAM domain protein
JRU67_RS04985	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JRU67_RS04990	COG0693	protein deglycase activity
JRU67_RS05005	COG0028	Belongs to the TPP enzyme family
JRU67_RS05010	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JRU67_RS05015	COG2137	regulation of response to DNA damage stimulus
JRU67_RS05025	COG1134	teichoic acid transport
JRU67_RS05035	COG1988	membrane-bound metal-dependent
JRU67_RS05040	COG1194	a g-specific adenine glycosylase
JRU67_RS05045	COG3557	Belongs to the UPF0374 family
JRU67_RS05055	COG0069	glutamate synthase activity
JRU67_RS05060	COG4129	membrane
JRU67_RS05065	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JRU67_RS05070	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JRU67_RS05080	COG0735	belongs to the Fur family
JRU67_RS05235	COG1609	Transcriptional regulator
JRU67_RS05265	COG1904	glucuronate isomerase
JRU67_RS05280	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JRU67_RS05285	COG0765	amino acid transport
JRU67_RS05290	COG1126	abc transporter atp-binding protein
JRU67_RS05295	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
JRU67_RS05300	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
JRU67_RS05305	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
JRU67_RS05310	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JRU67_RS05315	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
JRU67_RS05325	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
JRU67_RS05330	COG0363	glucosamine-6-phosphate deaminase activity
JRU67_RS05340	COG0114	fumarate hydratase activity
JRU67_RS05345	COG0248	Ppx GppA phosphatase
JRU67_RS05350	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
JRU67_RS05380	COG0564	pseudouridine synthase activity
JRU67_RS05385	COG3153	acetyltransferase
JRU67_RS05385	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JRU67_RS05390	COG4585	Histidine kinase
JRU67_RS05390	COG2203	Gaf domain
JRU67_RS05395	COG2197	response regulator
JRU67_RS05400	COG1301	dicarboxylic acid transport
JRU67_RS05410	COG4399	Belongs to the UPF0754 family
JRU67_RS05415	COG3679	Belongs to the UPF0342 family
JRU67_RS05420	COG0420	3'-5' exonuclease activity
JRU67_RS05430	COG3481	metal-dependent phosphohydrolase, HD sub domain
JRU67_RS05435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JRU67_RS05445	COG1846	Transcriptional regulator
JRU67_RS05455	COG0537	adenosine 5'-monophosphoramidase activity
JRU67_RS05460	COG1131	(ABC) transporter
JRU67_RS05470	COG2329	Antibiotic biosynthesis monooxygenase
JRU67_RS05475	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
JRU67_RS05480	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
JRU67_RS05485	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
JRU67_RS05540	COG0456	acetyltransferase
JRU67_RS05550	COG2814	Major facilitator Superfamily
JRU67_RS05575	COG0494	nUDIX hydrolase
JRU67_RS05580	COG1506	peptidase
JRU67_RS05585	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
JRU67_RS05590	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JRU67_RS05600	COG1012	belongs to the aldehyde dehydrogenase family
JRU67_RS05605	COG0656	L-ascorbic acid biosynthetic process
JRU67_RS05610	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JRU67_RS05630	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JRU67_RS05635	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JRU67_RS05655	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JRU67_RS05680	COG1595	DNA-templated transcription, initiation
JRU67_RS05730	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JRU67_RS05730	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JRU67_RS05735	COG0307	riboflavin synthase, alpha
JRU67_RS05740	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JRU67_RS05740	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JRU67_RS05750	COG0506	proline dehydrogenase activity
JRU67_RS05765	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
JRU67_RS05770	COG2267	carboxylic ester hydrolase activity
JRU67_RS05780	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
JRU67_RS05785	COG1242	4 iron, 4 sulfur cluster binding
JRU67_RS05790	COG2814	Major facilitator Superfamily
JRU67_RS05795	COG0495	leucyl-tRNA aminoacylation
JRU67_RS05800	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JRU67_RS05805	COG2081	HI0933 family
JRU67_RS05810	COG2244	polysaccharide biosynthetic process
JRU67_RS05815	COG1187	pseudouridine synthase activity
JRU67_RS05835	COG0510	thiamine kinase activity
JRU67_RS05840	COG0220	tRNA (guanine-N7-)-methyltransferase activity
JRU67_RS05845	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JRU67_RS05850	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
JRU67_RS05860	COG1363	Peptidase, m42
JRU67_RS05865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JRU67_RS05870	COG0765	amino acid transport
JRU67_RS05875	COG1126	abc transporter atp-binding protein
JRU67_RS05885	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JRU67_RS05890	COG4848	Belongs to the UPF0354 family
JRU67_RS05895	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JRU67_RS05900	COG1674	ftsk spoiiie
JRU67_RS05905	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JRU67_RS05910	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
JRU67_RS05915	COG4980	gas vesicle protein
JRU67_RS05920	COG1605	Chorismate mutase
JRU67_RS05920	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
JRU67_RS05925	COG1609	Transcriptional regulator
JRU67_RS05930	COG0123	including yeast histone deacetylase and acetoin utilization protein
JRU67_RS05935	COG0517	IMP dehydrogenase activity
JRU67_RS05940	COG0454	-acetyltransferase
JRU67_RS05945	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JRU67_RS05950	COG2759	Belongs to the formate--tetrahydrofolate ligase family
JRU67_RS05955	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JRU67_RS05960	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JRU67_RS05965	COG1704	LemA family
JRU67_RS05975	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JRU67_RS05980	COG0204	Acyl-transferase
JRU67_RS05995	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JRU67_RS06005	COG1764	response to oxidative stress
JRU67_RS06020	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JRU67_RS06025	COG1956	GAF domain-containing protein
JRU67_RS06030	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
JRU67_RS06035	COG1104	cysteine desulfurase activity
JRU67_RS06040	COG0301	tRNA thio-modification
JRU67_RS06050	COG2801	Transposase and inactivated derivatives
JRU67_RS06065	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JRU67_RS06070	COG0616	signal peptide processing
JRU67_RS06075	COG1714	RDD family
JRU67_RS06080	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
JRU67_RS06085	COG0827	DNA restriction-modification system
JRU67_RS06090	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JRU67_RS06105	COG0589	response to stress
JRU67_RS06110	COG0686	Belongs to the AlaDH PNT family
JRU67_RS06115	COG3142	Participates in the control of copper homeostasis
JRU67_RS06120	COG0006	proline dipeptidase activity
JRU67_RS06125	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
JRU67_RS06130	COG4109	DRTGG domain
JRU67_RS06140	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
JRU67_RS06150	COG0281	malic enzyme
JRU67_RS06155	COG1725	Transcriptional regulator
JRU67_RS06160	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
JRU67_RS06165	COG0825	malonyl-CoA metabolic process
JRU67_RS06170	COG0205	6-phosphofructokinase activity
JRU67_RS06175	COG0469	pyruvate kinase activity
JRU67_RS06180	COG1113	amino acid transport
JRU67_RS06185	COG0372	Belongs to the citrate synthase family
JRU67_RS06190	COG0538	isocitrate dehydrogenase activity
JRU67_RS06200	COG0745	RESPONSE REGULATOR receiver
JRU67_RS06205	COG5002	protein histidine kinase activity
JRU67_RS06210	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JRU67_RS06210	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JRU67_RS06215	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
JRU67_RS06220	COG0237	dephospho-CoA kinase activity
JRU67_RS06225	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JRU67_RS06235	COG3611	Membrane attachment protein
JRU67_RS06240	COG1484	DNA-dependent DNA replication
JRU67_RS06250	COG0833	amino acid
JRU67_RS06255	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
JRU67_RS06260	COG0291	Belongs to the bacterial ribosomal protein bL35 family
JRU67_RS06265	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
JRU67_RS06270	COG4112	unkown
JRU67_RS06280	COG0544	peptidyl-prolyl cis-trans isomerase activity
JRU67_RS06285	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JRU67_RS06290	COG0218	Necessary for normal cell division and for the maintenance of normal septation
JRU67_RS06295	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
JRU67_RS06300	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JRU67_RS06305	COG0181	hydroxymethylbilane synthase activity
JRU67_RS06315	COG0113	porphobilinogen synthase activity
JRU67_RS06320	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JRU67_RS06335	COG0285	dihydrofolate synthase activity
JRU67_RS06345	COG1288	antiporter activity
JRU67_RS06350	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
JRU67_RS06370	COG0640	Transcriptional regulator
JRU67_RS06395	COG0640	Transcriptional regulator
JRU67_RS06400	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JRU67_RS06405	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JRU67_RS06460	COG2249	NAD(P)H dehydrogenase (quinone) activity
JRU67_RS06465	COG0477	Major facilitator Superfamily
JRU67_RS06485	COG1132	(ABC) transporter
JRU67_RS06490	COG1132	(ABC) transporter
JRU67_RS06505	COG1792	Involved in formation and maintenance of cell shape
JRU67_RS06515	COG0261	This protein binds to 23S rRNA in the presence of protein L20
JRU67_RS06520	COG2868	ribosomal protein
JRU67_RS06525	COG0211	Belongs to the bacterial ribosomal protein bL27 family
JRU67_RS06535	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JRU67_RS06540	COG4492	Belongs to the UPF0735 family
JRU67_RS06545	COG0632	four-way junction helicase activity
JRU67_RS06550	COG2255	four-way junction helicase activity
JRU67_RS06560	COG0343	queuine tRNA-ribosyltransferase activity
JRU67_RS06565	COG1862	Preprotein translocase
JRU67_RS06570	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JRU67_RS06570	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JRU67_RS06575	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
JRU67_RS06575	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
JRU67_RS06585	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JRU67_RS06595	COG0860	N-Acetylmuramoyl-L-alanine amidase
JRU67_RS06600	COG0124	histidyl-tRNA synthetase
JRU67_RS06605	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
JRU67_RS06615	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
JRU67_RS06620	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JRU67_RS06625	COG1959	2 iron, 2 sulfur cluster binding
JRU67_RS06635	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JRU67_RS06640	COG0488	(ABC) transporter
JRU67_RS06645	COG1104	cysteine desulfurase activity
JRU67_RS06650	COG0482	sulfurtransferase activity
JRU67_RS06660	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
JRU67_RS06665	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JRU67_RS06670	COG4472	Bacterial protein of unknown function (DUF965)
JRU67_RS06675	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JRU67_RS06685	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JRU67_RS06690	COG4122	O-methyltransferase activity
JRU67_RS06695	COG0826	peptidase U32
JRU67_RS06700	COG0826	peptidase U32
JRU67_RS06705	COG0572	uridine kinase
JRU67_RS06710	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JRU67_RS06715	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
JRU67_RS06720	COG1984	allophanate hydrolase subunit 2
JRU67_RS06730	COG0439	Biotin carboxylase
JRU67_RS06735	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
JRU67_RS06740	COG1914	H( )-stimulated, divalent metal cation uptake system
JRU67_RS06745	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JRU67_RS06750	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
JRU67_RS06755	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JRU67_RS06760	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JRU67_RS06765	COG1534	Rna-binding protein
JRU67_RS06770	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JRU67_RS06775	COG1713	HD superfamily hydrolase involved in NAD metabolism
JRU67_RS06780	COG0799	negative regulation of ribosome biogenesis
JRU67_RS06785	COG2226	methyltransferase
JRU67_RS06790	COG1596	polysaccharide export
JRU67_RS06790	COG1555	photosystem II stabilization
JRU67_RS06795	COG2131	deaminase
JRU67_RS06810	COG1466	dna polymerase III delta subunit
JRU67_RS06815	COG0268	Binds directly to 16S ribosomal RNA
JRU67_RS06820	COG0481	GTPase activity
JRU67_RS06825	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JRU67_RS06835	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JRU67_RS06840	COG0443	Heat shock 70 kDa protein
JRU67_RS06850	COG2264	protein methyltransferase activity
JRU67_RS06855	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JRU67_RS06860	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JRU67_RS06865	COG0828	Belongs to the bacterial ribosomal protein bS21 family
JRU67_RS06870	COG1030	water channel activity
JRU67_RS06875	COG4864	UPF0365 protein
JRU67_RS06890	COG1702	phosphate starvation-inducible protein PhoH
JRU67_RS06895	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JRU67_RS06900	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
JRU67_RS06905	COG0295	cytidine deaminase activity
JRU67_RS06915	COG1381	Involved in DNA repair and RecF pathway recombination
JRU67_RS06920	COG0423	glycine-tRNA ligase activity
JRU67_RS06925	COG0517	IMP dehydrogenase activity
JRU67_RS06930	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
JRU67_RS06935	COG0358	DNA primase activity
JRU67_RS06940	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JRU67_RS06945	COG2010	Cytochrome c
JRU67_RS06950	COG2384	SAM-dependent methyltransferase
JRU67_RS06960	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
JRU67_RS06965	COG0513	Belongs to the DEAD box helicase family
JRU67_RS06970	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
JRU67_RS06975	COG1121	(ABC) transporter
JRU67_RS06980	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JRU67_RS06985	COG0735	belongs to the Fur family
JRU67_RS06990	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
JRU67_RS06995	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
JRU67_RS07005	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JRU67_RS07010	COG0768	penicillin binding
JRU67_RS07015	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
JRU67_RS07020	COG0573	inorganic phosphate transmembrane transporter activity
JRU67_RS07025	COG0581	inorganic phosphate transmembrane transporter activity
JRU67_RS07030	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JRU67_RS07035	COG0704	Plays a role in the regulation of phosphate uptake
JRU67_RS07040	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JRU67_RS07045	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JRU67_RS07050	COG0705	Rhomboid family
JRU67_RS07050	COG0457	Tetratricopeptide repeat
JRU67_RS07055	COG4483	Protein conserved in bacteria
JRU67_RS07060	COG1940	carbohydrate kinase activity
JRU67_RS07065	COG0011	TIGRFAM Protein of
JRU67_RS07075	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JRU67_RS07090	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JRU67_RS07100	COG2801	Transposase and inactivated derivatives
JRU67_RS07130	COG4537	Required for transformation and DNA binding
JRU67_RS07155	COG0404	The glycine cleavage system catalyzes the degradation of glycine
JRU67_RS07160	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JRU67_RS07165	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JRU67_RS07180	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JRU67_RS07185	COG0095	Lipoate-protein ligase
JRU67_RS07200	COG0006	proline dipeptidase activity
JRU67_RS07205	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JRU67_RS07210	COG0511	ligase activity, forming carbon-carbon bonds
JRU67_RS07215	COG0439	Biotin carboxylase
JRU67_RS07220	COG1302	Protein conserved in bacteria
JRU67_RS07245	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
JRU67_RS07250	COG1438	arginine binding
JRU67_RS07255	COG0497	DNA recombination
JRU67_RS07270	COG0280	phosphate acetyltransferase
JRU67_RS07285	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JRU67_RS07290	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JRU67_RS07295	COG0022	dehydrogenase e1 component
JRU67_RS07300	COG0508	dehydrogenase complex catalyzes the overall conversion of
JRU67_RS07310	COG4129	membrane
JRU67_RS07320	COG2195	Cleaves the N-terminal amino acid of tripeptides
JRU67_RS07330	COG2207	Transcriptional regulator
JRU67_RS07330	COG1917	Cupin 2, conserved barrel domain protein
JRU67_RS07335	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JRU67_RS07340	COG1234	tRNA 3'-trailer cleavage
JRU67_RS07345	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JRU67_RS07355	COG0667	Aldo Keto reductase
JRU67_RS07365	COG0735	belongs to the Fur family
JRU67_RS07370	COG4974	Belongs to the 'phage' integrase family
JRU67_RS07375	COG1547	Domain of unknown function (DUF309)
JRU67_RS07380	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
JRU67_RS07385	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JRU67_RS07390	COG1187	pseudouridine synthase activity
JRU67_RS07395	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JRU67_RS07400	COG1333	cytochrome c biogenesis protein
JRU67_RS07405	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JRU67_RS07410	COG0745	RESPONSE REGULATOR receiver
JRU67_RS07415	COG5002	protein histidine kinase activity
JRU67_RS07425	COG1141	Ferredoxin
JRU67_RS07430	COG4955	Helix-turn-helix domain
JRU67_RS07435	COG0514	ATP-dependent DNA helicase (RecQ)
JRU67_RS07450	COG0492	ferredoxin-NADP+ reductase activity
JRU67_RS07455	COG0252	asparaginase activity
JRU67_RS07460	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
JRU67_RS07465	COG0539	negative regulation of cytoplasmic translation
JRU67_RS07470	COG1160	GTP binding
JRU67_RS07475	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
JRU67_RS07500	COG2226	methyltransferase
JRU67_RS07505	COG0142	geranyltranstransferase activity
JRU67_RS07510	COG0105	UTP biosynthetic process
JRU67_RS07515	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
JRU67_RS07520	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JRU67_RS07525	COG0457	Tetratricopeptide repeat
JRU67_RS07550	COG0723	plastoquinol--plastocyanin reductase activity
JRU67_RS07555	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
JRU67_RS07570	COG2738	Putative neutral zinc metallopeptidase
JRU67_RS07575	COG1694	Mazg nucleotide pyrophosphohydrolase
JRU67_RS07580	COG0438	transferase activity, transferring glycosyl groups
JRU67_RS07585	COG0617	tRNA 3'-terminal CCA addition
JRU67_RS07595	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JRU67_RS07595	COG1199	ATP-dependent helicase activity
JRU67_RS07605	COG3935	DnaD domain protein
JRU67_RS07610	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JRU67_RS07620	COG4499	WXG100 protein secretion system (Wss), protein YukC
JRU67_RS07620	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JRU67_RS07625	COG3331	DNA recombination
JRU67_RS07635	COG4474	Belongs to the UPF0398 family
JRU67_RS07640	COG3599	regulation of cell shape
JRU67_RS07650	COG0116	Belongs to the methyltransferase superfamily
JRU67_RS07665	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JRU67_RS07675	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
JRU67_RS07680	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JRU67_RS07685	COG0328	RNA-DNA hybrid ribonuclease activity
JRU67_RS07710	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
JRU67_RS07720	COG1413	lyase activity
JRU67_RS07735	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
JRU67_RS07745	COG0204	Acyl-transferase
JRU67_RS07765	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JRU67_RS07770	COG2190	(PTS) system
JRU67_RS07775	COG4479	Belongs to the UPF0346 family
JRU67_RS07800	COG0671	phosphoesterase, PA-phosphatase related
JRU67_RS07810	COG5002	protein histidine kinase activity
JRU67_RS07815	COG0567	Dehydrogenase, E1 component
JRU67_RS07835	COG2267	carboxylic ester hydrolase activity
JRU67_RS07840	COG3328	transposase activity
JRU67_RS07860	COG0714	Associated with various cellular activities
JRU67_RS07865	COG4548	von Willebrand factor, type A
JRU67_RS07875	COG5505	Protein of unknown function (DUF819)
JRU67_RS07880	COG2801	Transposase and inactivated derivatives
JRU67_RS07885	COG2801	Transposase and inactivated derivatives
JRU67_RS07910	COG3853	Toxic anion resistance protein (TelA)
JRU67_RS07920	COG1254	Belongs to the acylphosphatase family
JRU67_RS07955	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JRU67_RS07960	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JRU67_RS07965	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JRU67_RS07970	COG0527	aspartate kinase activity
JRU67_RS07975	COG0488	(ABC) transporter
JRU67_RS07980	COG2996	Protein conserved in bacteria
JRU67_RS07985	COG3711	transcriptional antiterminator
JRU67_RS07990	COG1447	Phosphotransferase system cellobiose-specific component IIA
JRU67_RS07995	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JRU67_RS07995	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JRU67_RS08005	COG3684	Belongs to the aldolase LacD family
JRU67_RS08010	COG1105	Belongs to the carbohydrate kinase PfkB family
JRU67_RS08015	COG0698	ribose 5-phosphate isomerase
JRU67_RS08025	COG1349	DNA-binding transcription factor activity
JRU67_RS08030	COG1164	Oligoendopeptidase f
JRU67_RS08045	COG0789	Transcriptional regulator
JRU67_RS08080	COG2801	Transposase and inactivated derivatives
JRU67_RS08090	COG0159	tryptophan synthase activity
JRU67_RS08100	COG0135	phosphoribosylanthranilate isomerase activity
JRU67_RS08110	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JRU67_RS08115	COG0512	Glutamine amidotransferase of anthranilate synthase
JRU67_RS08120	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JRU67_RS08125	COG1363	Peptidase, m42
JRU67_RS08130	COG0287	Prephenate dehydrogenase
JRU67_RS08145	COG2801	Transposase and inactivated derivatives
JRU67_RS08150	COG2801	Transposase and inactivated derivatives
JRU67_RS08165	COG1476	TRANSCRIPTIONal
JRU67_RS08170	COG1757	Na H antiporter
JRU67_RS08175	COG1929	Belongs to the glycerate kinase type-1 family
JRU67_RS08180	COG0471	metal ion transport
JRU67_RS08200	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JRU67_RS08235	COG0586	Pfam SNARE associated Golgi protein
JRU67_RS08255	COG0628	permease
JRU67_RS08260	COG2190	(PTS) system
JRU67_RS08260	COG1263	PTS System
JRU67_RS08260	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JRU67_RS08265	COG3711	transcriptional antiterminator
JRU67_RS08275	COG1115	amino acid carrier protein
JRU67_RS08280	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JRU67_RS08290	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
JRU67_RS08295	COG4841	protein insertion into membrane
JRU67_RS08300	COG0824	Thioesterase
JRU67_RS08310	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JRU67_RS08315	COG1970	mechanosensitive ion channel activity
JRU67_RS08320	COG1999	signal sequence binding
JRU67_RS08345	COG4846	Membrane protein involved in cytochrome C biogenesis
JRU67_RS08350	COG0785	Cytochrome C biogenesis protein
JRU67_RS08355	COG3763	UPF0154 protein
JRU67_RS08365	COG4224	UPF0291 protein
JRU67_RS08375	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JRU67_RS08390	COG0516	GMP reductase activity
JRU67_RS08395	COG0803	Belongs to the bacterial solute-binding protein 9 family
JRU67_RS08400	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JRU67_RS08405	COG0833	amino acid
JRU67_RS08420	COG0640	Transcriptional regulator
JRU67_RS08445	COG0083	homoserine kinase activity
JRU67_RS08450	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
JRU67_RS08455	COG0460	homoserine dehydrogenase
JRU67_RS08460	COG0527	aspartate kinase activity
JRU67_RS08475	COG2084	Dehydrogenase
JRU67_RS08490	COG1597	lipid kinase activity
JRU67_RS08535	COG0789	Transcriptional regulator
JRU67_RS08540	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
JRU67_RS08545	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JRU67_RS08550	COG0386	Belongs to the glutathione peroxidase family
JRU67_RS08555	COG1923	regulation of RNA biosynthetic process
JRU67_RS08560	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JRU67_RS08565	COG2267	carboxylic ester hydrolase activity
JRU67_RS08570	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
JRU67_RS08575	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JRU67_RS08580	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JRU67_RS08585	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
JRU67_RS08590	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JRU67_RS08595	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JRU67_RS08605	COG4550	Control of competence regulator ComK, YlbF/YmcA
JRU67_RS08610	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JRU67_RS08620	COG1132	(ABC) transporter
JRU67_RS08625	COG1132	(ABC) transporter
JRU67_RS08635	COG1013	pyruvate-flavodoxin oxidoreductase activity
JRU67_RS08640	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
JRU67_RS08640	COG0674	pyruvate-flavodoxin oxidoreductase activity
JRU67_RS08645	COG1692	metallophosphoesterase
JRU67_RS08655	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JRU67_RS08655	COG0463	Glycosyl transferase, family 2
JRU67_RS08680	COG0561	phosphatase activity
JRU67_RS08685	COG1917	Cupin 2, conserved barrel domain protein
JRU67_RS08685	COG2207	Transcriptional regulator
JRU67_RS08690	COG0697	spore germination
JRU67_RS08725	COG0596	Alpha beta hydrolase
JRU67_RS08735	COG1215	transferase activity, transferring glycosyl groups
JRU67_RS08745	COG1418	mRNA catabolic process
JRU67_RS08750	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JRU67_RS08755	COG1058	Belongs to the CinA family
JRU67_RS08755	COG1546	Belongs to the CinA family
JRU67_RS08775	COG0300	oxidoreductase activity
JRU67_RS08780	COG0612	Peptidase, M16
JRU67_RS08790	COG2188	Transcriptional regulator
JRU67_RS08800	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JRU67_RS08805	COG0612	Peptidase, M16
JRU67_RS08810	COG1185	polyribonucleotide nucleotidyltransferase activity
JRU67_RS08820	COG0196	riboflavin kinase activity
JRU67_RS08825	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JRU67_RS08830	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JRU67_RS08855	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JRU67_RS08860	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JRU67_RS08865	COG2169	Transcriptional regulator
JRU67_RS08875	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JRU67_RS08880	COG1358	cellular component organization or biogenesis
JRU67_RS08885	COG2740	Nucleic-acid-binding protein implicated in transcription termination
JRU67_RS08890	COG0195	Participates in both transcription termination and antitermination
JRU67_RS08895	COG0779	Required for maturation of 30S ribosomal subunits
JRU67_RS08905	COG0442	prolyl-tRNA aminoacylation
JRU67_RS08915	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
JRU67_RS08920	COG4589	Belongs to the CDS family
JRU67_RS08930	COG0233	cytoplasmic translational termination
JRU67_RS08935	COG0528	UMP kinase activity
JRU67_RS08940	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JRU67_RS08945	COG0052	Belongs to the universal ribosomal protein uS2 family
JRU67_RS08955	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
JRU67_RS08960	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
JRU67_RS08965	COG4974	Belongs to the 'phage' integrase family
JRU67_RS08970	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
JRU67_RS08975	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JRU67_RS08980	COG0758	DNA mediated transformation
JRU67_RS08990	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
JRU67_RS08995	COG0045	succinate-CoA ligase (ADP-forming) activity
JRU67_RS09000	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JRU67_RS09005	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JRU67_RS09010	COG0463	Glycosyl transferase, family 2
JRU67_RS09015	COG4485	Bacterial membrane protein, YfhO
JRU67_RS09020	COG0335	large ribosomal subunit rRNA binding
JRU67_RS09025	COG0336	Belongs to the RNA methyltransferase TrmD family
JRU67_RS09035	COG1837	Belongs to the UPF0109 family
JRU67_RS09040	COG0228	four-way junction DNA binding
JRU67_RS09045	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JRU67_RS09050	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
JRU67_RS09055	COG0552	protein localization to endoplasmic reticulum
JRU67_RS09060	COG1196	nuclear chromosome segregation
JRU67_RS09080	COG2801	Transposase and inactivated derivatives
JRU67_RS09085	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JRU67_RS09085	COG0463	Glycosyl transferase, family 2
JRU67_RS09430	COG3617	BRO family, N-terminal domain
JRU67_RS09450	COG3620	sequence-specific DNA binding
JRU67_RS09480	COG0582	viral genome integration into host DNA
JRU67_RS09485	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JRU67_RS09500	COG0416	fatty acid biosynthetic process
JRU67_RS09505	COG1349	DNA-binding transcription factor activity
JRU67_RS09520	COG3764	Sortase (surface protein transpeptidase)
JRU67_RS09525	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JRU67_RS09530	COG1760	l-serine dehydratase
JRU67_RS09535	COG1760	l-serine dehydratase
JRU67_RS09545	COG1302	Protein conserved in bacteria
JRU67_RS09550	COG0227	Belongs to the bacterial ribosomal protein bL28 family
JRU67_RS09555	COG1564	THIamine pyrophosphokinase
JRU67_RS09560	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JRU67_RS09565	COG1162	GTPase activity
JRU67_RS09570	COG3850	Histidine kinase
JRU67_RS09570	COG5002	protein histidine kinase activity
JRU67_RS09575	COG0745	RESPONSE REGULATOR receiver
JRU67_RS09580	COG2124	cytochrome p450
JRU67_RS09600	COG0820	rRNA (adenine-C2-)-methyltransferase activity
JRU67_RS09605	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JRU67_RS09605	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JRU67_RS09610	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JRU67_RS09615	COG0242	peptide deformylase activity
JRU67_RS09630	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JRU67_RS09635	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JRU67_RS09640	COG1758	RNA polymerase activity
JRU67_RS09660	COG0471	metal ion transport
JRU67_RS09675	COG0284	orotidine-5'-phosphate decarboxylase activity
JRU67_RS09680	COG0167	dihydroorotate dehydrogenase activity
JRU67_RS09685	COG0543	2 iron, 2 sulfur cluster binding
JRU67_RS09690	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JRU67_RS09695	COG0505	Belongs to the CarA family
JRU67_RS09705	COG0540	Belongs to the ATCase OTCase family
JRU67_RS09715	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JRU67_RS09720	COG0564	pseudouridine synthase activity
JRU67_RS09725	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JRU67_RS09735	COG3591	Belongs to the peptidase S1B family
JRU67_RS09745	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JRU67_RS09750	COG3599	regulation of cell shape
JRU67_RS09760	COG0762	integral membrane protein
JRU67_RS09765	COG1799	cell septum assembly
JRU67_RS09770	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
JRU67_RS09775	COG1496	oxidoreductase activity
JRU67_RS09780	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JRU67_RS09785	COG0849	cell division
JRU67_RS09790	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
JRU67_RS09795	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JRU67_RS09800	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JRU67_RS09805	COG0768	penicillin binding
JRU67_RS09810	COG4839	cell division protein FtsL
JRU67_RS09815	COG0275	rRNA processing
JRU67_RS09820	COG2001	Belongs to the MraZ family
JRU67_RS09825	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
JRU67_RS09830	COG0454	-acetyltransferase
JRU67_RS09850	COG0366	Alpha amylase catalytic
JRU67_RS09855	COG0456	acetyltransferase
JRU67_RS09855	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
JRU67_RS09885	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JRU67_RS09895	COG1846	Transcriptional regulator
JRU67_RS09900	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JRU67_RS09905	COG1053	succinate dehydrogenase
JRU67_RS09910	COG2009	succinate dehydrogenase
JRU67_RS09915	COG0322	excinuclease ABC activity
JRU67_RS09920	COG3118	belongs to the thioredoxin family
JRU67_RS09925	COG1024	Enoyl-CoA hydratase
JRU67_RS09935	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JRU67_RS09935	COG1796	DNA polymerase
JRU67_RS09945	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
JRU67_RS09950	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JRU67_RS09955	COG0072	phenylalanine-tRNA ligase activity
JRU67_RS09955	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JRU67_RS09960	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JRU67_RS09965	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JRU67_RS09985	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JRU67_RS09990	COG0742	ribosomal rna small subunit methyltransferase
JRU67_RS10000	COG4471	UPF0298 protein
JRU67_RS10005	COG0584	glycerophosphoryl diester phosphodiesterase
JRU67_RS10010	COG3679	Belongs to the UPF0342 family
JRU67_RS10015	COG2340	Cysteine-rich secretory protein family
JRU67_RS10025	COG0628	permease
JRU67_RS10035	COG3336	cytochrome c oxidase
JRU67_RS10060	COG0109	protoheme IX farnesyltransferase activity
JRU67_RS10065	COG1612	heme a metabolic process
JRU67_RS10075	COG0772	Belongs to the SEDS family
JRU67_RS10080	COG4838	Belongs to the UPF0358 family
JRU67_RS10090	COG4896	Protein conserved in bacteria
JRU67_RS10105	COG1217	gtp-binding protein TYPA
JRU67_RS10115	COG0483	inositol monophosphate 1-phosphatase activity
JRU67_RS10135	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
JRU67_RS10140	COG1177	transmembrane transport
JRU67_RS10145	COG1176	ABC-type spermidine putrescine transport system, permease component I
JRU67_RS10150	COG3842	ATPase activity
JRU67_RS10160	COG4476	Belongs to the UPF0223 family
JRU67_RS10180	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JRU67_RS10190	COG0242	peptide deformylase activity
JRU67_RS10200	COG0561	phosphatase activity
JRU67_RS10205	COG5503	Protein of unknown function (DUF1447)
JRU67_RS10215	COG0569	domain protein
JRU67_RS10225	COG1271	oxidase subunit
JRU67_RS10255	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JRU67_RS10265	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JRU67_RS10280	COG1122	ATPase activity
JRU67_RS10290	COG0151	Belongs to the GarS family
JRU67_RS10295	COG0138	bifunctional purine biosynthesis protein purh
JRU67_RS10305	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
JRU67_RS10325	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JRU67_RS10330	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
JRU67_RS10340	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JRU67_RS10375	COG3964	amidohydrolase
JRU67_RS10385	COG1017	nitric oxide dioxygenase activity
JRU67_RS10385	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JRU67_RS10390	COG1959	2 iron, 2 sulfur cluster binding
JRU67_RS10400	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JRU67_RS10405	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JRU67_RS10410	COG1845	cytochrome c oxidase, subunit III
JRU67_RS10415	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
JRU67_RS10435	COG0438	transferase activity, transferring glycosyl groups
JRU67_RS10440	COG1134	teichoic acid transport
JRU67_RS10450	COG1682	transport, permease protein
JRU67_RS10470	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
JRU67_RS10485	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JRU67_RS10485	COG0463	Glycosyl transferase, family 2
JRU67_RS10490	COG0463	Glycosyl transferase, family 2
JRU67_RS10490	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JRU67_RS10495	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
JRU67_RS10505	COG1215	transferase activity, transferring glycosyl groups
JRU67_RS10510	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JRU67_RS10515	COG1682	transport, permease protein
JRU67_RS10520	COG1134	teichoic acid transport
JRU67_RS10545	COG0183	Belongs to the thiolase family
JRU67_RS10550	COG0318	PFAM AMP-dependent synthetase and ligase
JRU67_RS10555	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
JRU67_RS10560	COG1316	TRANSCRIPTIONal
JRU67_RS10575	COG2153	protein acetylation
JRU67_RS10585	COG3594	Acyltransferase
JRU67_RS10595	COG0436	Aminotransferase
JRU67_RS10600	COG4187	Peptidase family M20/M25/M40
JRU67_RS10610	COG2801	Transposase and inactivated derivatives
JRU67_RS10625	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
JRU67_RS10630	COG0596	Alpha beta hydrolase
JRU67_RS10640	COG1169	isochorismate synthase
JRU67_RS10645	COG1575	Belongs to the MenA family. Type 1 subfamily
JRU67_RS10710	COG4873	Protein conserved in bacteria
JRU67_RS10720	COG0737	Belongs to the 5'-nucleotidase family
JRU67_RS10725	COG3852	Histidine kinase
JRU67_RS10735	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JRU67_RS10740	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JRU67_RS10740	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JRU67_RS10745	COG0861	Integral membrane protein TerC family
JRU67_RS10750	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
JRU67_RS10760	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JRU67_RS10780	COG2814	Major facilitator Superfamily
JRU67_RS10785	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
JRU67_RS10790	COG2382	esterase
JRU67_RS10795	COG1115	amino acid carrier protein
JRU67_RS10800	COG0628	permease
JRU67_RS10815	COG0475	glutathione-regulated potassium exporter activity
JRU67_RS10815	COG0569	domain protein
JRU67_RS10820	COG2239	Acts as a magnesium transporter
JRU67_RS10825	COG0564	pseudouridine synthase activity
JRU67_RS10835	COG2357	RelA SpoT domain protein
JRU67_RS10845	COG4116	CYTH
JRU67_RS10850	COG2346	COG2346, Truncated hemoglobins
JRU67_RS10855	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
JRU67_RS10860	COG1164	Oligoendopeptidase f
JRU67_RS10870	COG4862	establishment of competence for transformation
JRU67_RS10875	COG1393	Belongs to the ArsC family
JRU67_RS10885	COG4166	transmembrane transport
JRU67_RS10890	COG4166	transmembrane transport
JRU67_RS10895	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
JRU67_RS10905	COG4166	transmembrane transport
JRU67_RS10910	COG4166	transmembrane transport
JRU67_RS10915	COG4608	Belongs to the ABC transporter superfamily
JRU67_RS10920	COG0444	Belongs to the ABC transporter superfamily
JRU67_RS10925	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JRU67_RS10930	COG0601	transmembrane transport
JRU67_RS10955	COG0542	response to heat
JRU67_RS10960	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JRU67_RS10970	COG2151	metal-sulfur cluster biosynthetic enzyme
JRU67_RS10975	COG0561	phosphatase activity
JRU67_RS10980	COG1307	EDD domain protein, DegV family
JRU67_RS10990	COG0366	Alpha amylase catalytic
JRU67_RS10990	COG1874	Beta-galactosidase
JRU67_RS11000	COG0179	Fumarylacetoacetate (FAA) hydrolase
JRU67_RS11005	COG2311	Membrane
JRU67_RS11015	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
JRU67_RS11030	COG0398	Pfam SNARE associated Golgi protein
JRU67_RS11050	COG0137	argininosuccinate synthase activity
JRU67_RS11055	COG0165	Argininosuccinate lyase
JRU67_RS11065	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JRU67_RS11070	COG1012	belongs to the aldehyde dehydrogenase family
JRU67_RS11075	COG1098	S1 RNA binding domain
JRU67_RS11085	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JRU67_RS11095	COG2111	Na H antiporter
JRU67_RS11095	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JRU67_RS11100	COG2111	Na H antiporter
JRU67_RS11115	COG1863	multisubunit Na H antiporter MnhE subunit
JRU67_RS11120	COG2212	antiporter activity
JRU67_RS11125	COG1320	monovalent cation:proton antiporter activity
JRU67_RS11130	COG2050	protein possibly involved in aromatic compounds catabolism
JRU67_RS11135	COG2056	Na+-H+ antiporter family
JRU67_RS11140	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JRU67_RS11150	COG1252	NADH dehydrogenase
JRU67_RS11155	COG0316	Belongs to the HesB IscA family
JRU67_RS11160	COG4844	belongs to the
JRU67_RS11165	COG1252	NADH dehydrogenase
JRU67_RS11185	COG4837	Protein of unknown function (DUF1462)
JRU67_RS11190	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
JRU67_RS11195	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
JRU67_RS11200	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JRU67_RS11205	COG1696	Membrane protein involved in D-alanine export
JRU67_RS11210	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JRU67_RS11220	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JRU67_RS11225	COG0647	UMP catabolic process
JRU67_RS11230	COG2445	Protein of unknown function DUF86
JRU67_RS11240	COG4470	Protein conserved in bacteria
JRU67_RS11245	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
JRU67_RS11250	COG0737	Belongs to the 5'-nucleotidase family
JRU67_RS11255	COG0730	response to heat
JRU67_RS11260	COG1801	Protein of unknown function DUF72
JRU67_RS11265	COG1136	(ABC) transporter
JRU67_RS11285	COG1388	LysM domain
JRU67_RS11285	COG0860	N-Acetylmuramoyl-L-alanine amidase
JRU67_RS11295	COG1395	domain, Protein
JRU67_RS11310	COG0800	Aldolase
JRU67_RS11315	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JRU67_RS11320	COG1028	Short-chain dehydrogenase reductase Sdr
JRU67_RS11325	COG1940	carbohydrate kinase activity
JRU67_RS11330	COG2814	Major facilitator Superfamily
JRU67_RS11335	COG0719	Fe-S assembly protein
JRU67_RS11340	COG0822	iron-sulfur transferase activity
JRU67_RS11345	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JRU67_RS11350	COG0719	Fe-S assembly protein
JRU67_RS11355	COG0396	ATPase activity
JRU67_RS11375	COG1464	Belongs to the NlpA lipoprotein family
JRU67_RS11380	COG2011	ABC-type metal ion transport system permease component
JRU67_RS11385	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JRU67_RS11395	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
JRU67_RS11400	COG0509	glycine decarboxylation via glycine cleavage system
JRU67_RS11405	COG1393	Belongs to the ArsC family
JRU67_RS11410	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JRU67_RS11420	COG0778	Nitroreductase
JRU67_RS11420	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
JRU67_RS11425	COG0710	3-dehydroquinate dehydratase activity
JRU67_RS11445	COG0697	spore germination
JRU67_RS11450	COG1764	response to oxidative stress
JRU67_RS11475	COG1694	Mazg nucleotide pyrophosphohydrolase
JRU67_RS11490	COG4166	transmembrane transport
JRU67_RS11500	COG0494	nUDIX hydrolase
JRU67_RS11510	COG0523	cobalamin synthesis protein
JRU67_RS11515	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JRU67_RS11555	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JRU67_RS11560	COG1404	Belongs to the peptidase S8 family
JRU67_RS11610	COG2211	Major facilitator Superfamily
JRU67_RS11615	COG1262	PFAM Formylglycine-generating sulfatase enzyme
JRU67_RS11645	COG0406	alpha-ribazole phosphatase activity
JRU67_RS11655	COG1525	nuclease
JRU67_RS11670	COG1280	lysine exporter protein (LysE YggA)
JRU67_RS11700	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JRU67_RS11825	COG0740	serine-type endopeptidase activity
JRU67_RS11855	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JRU67_RS12005	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
JRU67_RS12010	COG0557	exoribonuclease II activity
JRU67_RS12015	COG1647	Serine aminopeptidase, S33
JRU67_RS12020	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JRU67_RS12025	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
JRU67_RS12035	COG0148	phosphopyruvate hydratase activity
JRU67_RS12045	COG0149	triose-phosphate isomerase activity
JRU67_RS12050	COG0126	phosphoglycerate kinase activity
JRU67_RS12070	COG0740	serine-type endopeptidase activity
JRU67_RS12075	COG1481	regulation of sporulation
JRU67_RS12085	COG0391	Required for morphogenesis under gluconeogenic growth conditions
JRU67_RS12090	COG1660	Displays ATPase and GTPase activities
JRU67_RS12105	COG0110	maltose O-acetyltransferase activity
JRU67_RS12110	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JRU67_RS12115	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
JRU67_RS12130	COG0556	nucleotide-excision repair
JRU67_RS12145	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JRU67_RS12150	COG3942	CHAP domain
JRU67_RS12155	COG2010	Cytochrome c
JRU67_RS12165	COG0653	protein targeting
JRU67_RS12170	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JRU67_RS12175	COG1040	competence protein
JRU67_RS12180	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
JRU67_RS12185	COG1307	EDD domain protein, DegV family
JRU67_RS12195	COG1739	Uncharacterized protein family UPF0029
JRU67_RS12200	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JRU67_RS12205	COG2199	diguanylate cyclase activity
JRU67_RS12210	COG2966	Psort location CytoplasmicMembrane, score
JRU67_RS12220	COG2195	Cleaves the N-terminal amino acid of tripeptides
JRU67_RS12225	COG1929	Belongs to the glycerate kinase type-1 family
JRU67_RS12255	COG4607	ABC-type enterochelin transport system periplasmic component
JRU67_RS12260	COG4604	ABC transporter, ATP-binding protein
JRU67_RS12265	COG4605	iron ion homeostasis
JRU67_RS12270	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JRU67_RS12280	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JRU67_RS12285	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JRU67_RS12290	COG1780	Probably involved in ribonucleotide reductase function
JRU67_RS12300	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
JRU67_RS12305	COG3104	oligopeptide transport
JRU67_RS12310	COG3104	oligopeptide transport
JRU67_RS12315	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
JRU67_RS12325	COG1174	glycine betaine transport
JRU67_RS12330	COG1125	glycine betaine transport
JRU67_RS12330	COG0517	IMP dehydrogenase activity
JRU67_RS12335	COG0514	ATP-dependent DNA helicase (RecQ)
JRU67_RS12340	COG0488	(ABC) transporter
JRU67_RS12350	COG1368	sulfuric ester hydrolase activity
JRU67_RS12355	COG1984	allophanate hydrolase subunit 2
JRU67_RS12370	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JRU67_RS12375	COG0512	Glutamine amidotransferase of anthranilate synthase
JRU67_RS12385	COG0720	synthase
JRU67_RS12390	COG0602	queuosine metabolic process
JRU67_RS12400	COG1695	Transcriptional regulator
JRU67_RS12420	COG0656	L-ascorbic acid biosynthetic process
JRU67_RS12425	COG1187	pseudouridine synthase activity
JRU67_RS12430	COG2814	Major facilitator Superfamily
JRU67_RS12435	COG1253	flavin adenine dinucleotide binding
JRU67_RS12440	COG2267	carboxylic ester hydrolase activity
JRU67_RS12445	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JRU67_RS12445	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JRU67_RS12445	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JRU67_RS12450	COG1105	Belongs to the carbohydrate kinase PfkB family
JRU67_RS12455	COG1349	DNA-binding transcription factor activity
JRU67_RS12460	COG1473	amidohydrolase
JRU67_RS12465	COG4989	oxidoreductase activity
JRU67_RS12470	COG0523	cobalamin synthesis protein
JRU67_RS12480	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
JRU67_RS12485	COG4988	ABC transporter
JRU67_RS12490	COG1968	undecaprenyl-diphosphatase activity
JRU67_RS12500	COG1671	Belongs to the UPF0178 family
JRU67_RS12515	COG1683	Conserved Protein
JRU67_RS12530	COG1012	belongs to the aldehyde dehydrogenase family
JRU67_RS12550	COG0025	NhaP-type Na H and K H
JRU67_RS12575	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JRU67_RS12580	COG0765	amino acid transport
JRU67_RS12585	COG0765	amino acid transport
JRU67_RS12590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JRU67_RS12595	COG1126	abc transporter atp-binding protein
JRU67_RS12605	COG0778	Nitroreductase
JRU67_RS12610	COG1136	(ABC) transporter
JRU67_RS12615	COG0577	efflux transmembrane transporter activity
JRU67_RS12625	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
JRU67_RS12630	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JRU67_RS12645	COG1263	PTS System
JRU67_RS12645	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JRU67_RS12655	COG0010	Belongs to the arginase family
JRU67_RS12660	COG1914	H( )-stimulated, divalent metal cation uptake system
JRU67_RS12700	COG2818	Glycosylase
JRU67_RS12710	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JRU67_RS12725	COG0667	Aldo Keto reductase
JRU67_RS12730	COG0492	ferredoxin-NADP+ reductase activity
JRU67_RS12735	COG2207	Transcriptional regulator
JRU67_RS12740	COG2271	Major facilitator Superfamily
JRU67_RS12745	COG3226	Transcriptional regulator
JRU67_RS12755	COG1253	flavin adenine dinucleotide binding
JRU67_RS12765	COG2197	response regulator
JRU67_RS12770	COG4585	Histidine kinase
JRU67_RS12775	COG0842	Transport permease protein
JRU67_RS12780	COG1131	(ABC) transporter
JRU67_RS12815	COG1132	(ABC) transporter
JRU67_RS12825	COG2264	protein methyltransferase activity
JRU67_RS12830	COG0803	Belongs to the bacterial solute-binding protein 9 family
JRU67_RS12830	COG3443	Belongs to the bacterial solute-binding protein 9 family
JRU67_RS12845	COG1136	(ABC) transporter
JRU67_RS12865	COG4607	ABC-type enterochelin transport system periplasmic component
JRU67_RS12875	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
JRU67_RS12880	COG2162	N-hydroxyarylamine O-acetyltransferase activity
JRU67_RS12890	COG0477	Major facilitator Superfamily
JRU67_RS12895	COG0477	Major facilitator Superfamily
JRU67_RS12905	COG3732	PTS system glucitol sorbitol-specific
JRU67_RS12910	COG3730	PTS system glucitol sorbitol-specific
JRU67_RS12920	COG3711	transcriptional antiterminator
JRU67_RS12920	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JRU67_RS12935	COG3328	transposase activity
JRU67_RS12945	COG2801	Transposase and inactivated derivatives
JRU67_RS12950	COG0463	Glycosyl transferase, family 2
JRU67_RS12950	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JRU67_RS12960	COG2801	Transposase and inactivated derivatives
JRU67_RS12990	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JRU67_RS12995	COG0740	serine-type endopeptidase activity
JRU67_RS13000	COG1309	transcriptional regulator
JRU67_RS13010	COG4808	Protein conserved in bacteria
JRU67_RS13015	COG0400	carboxylic ester hydrolase activity
JRU67_RS13020	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JRU67_RS13025	COG0346	lactoylglutathione lyase activity
JRU67_RS13030	COG1846	Transcriptional regulator
JRU67_RS13035	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JRU67_RS13040	COG0626	cystathionine gamma-synthase activity
JRU67_RS13050	COG4978	Transcriptional regulator
JRU67_RS13050	COG0789	Transcriptional regulator
JRU67_RS13065	COG1131	(ABC) transporter
JRU67_RS13070	COG2188	Transcriptional regulator
JRU67_RS13075	COG2819	hydrolase of the alpha beta superfamily
JRU67_RS13080	COG0693	protein deglycase activity
JRU67_RS13085	COG3173	Aminoglycoside phosphotransferase
JRU67_RS13095	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JRU67_RS13100	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JRU67_RS13110	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JRU67_RS13110	COG0463	Glycosyl transferase, family 2
JRU67_RS13120	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JRU67_RS13125	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JRU67_RS13135	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JRU67_RS13140	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JRU67_RS13145	COG0463	Glycosyl transferase, family 2
JRU67_RS13145	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JRU67_RS13155	COG1486	melibiose metabolic process
JRU67_RS13160	COG3328	transposase activity
JRU67_RS13165	COG0438	transferase activity, transferring glycosyl groups
JRU67_RS13175	COG1959	2 iron, 2 sulfur cluster binding
JRU67_RS13180	COG2910	NAD(P)H-binding
JRU67_RS13185	COG1388	LysM domain
JRU67_RS13220	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
JRU67_RS13225	COG1902	pentaerythritol trinitrate reductase activity
JRU67_RS13230	COG3037	sugar-specific permease SgaT UlaA
JRU67_RS13240	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JRU67_RS13250	COG2723	6-phospho-beta-galactosidase activity
JRU67_RS13255	COG2723	6-phospho-beta-galactosidase activity
JRU67_RS13260	COG2190	(PTS) system
JRU67_RS13260	COG1263	PTS System
JRU67_RS13260	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JRU67_RS13265	COG3711	transcriptional antiterminator
JRU67_RS13275	COG3239	Fatty acid desaturase
JRU67_RS13285	COG1363	Peptidase, m42
JRU67_RS13295	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
JRU67_RS13300	COG2357	RelA SpoT domain protein
JRU67_RS13305	COG1486	melibiose metabolic process
JRU67_RS13310	COG1263	PTS System
JRU67_RS13310	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JRU67_RS13315	COG1737	Transcriptional regulator
JRU67_RS13320	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JRU67_RS13325	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JRU67_RS13330	COG1279	arginine transmembrane transporter activity
JRU67_RS13340	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JRU67_RS13340	COG1263	PTS System
JRU67_RS13345	COG2824	Alkylphosphonate utilization operon protein PhnA
JRU67_RS13360	COG1131	(ABC) transporter
JRU67_RS13370	COG1113	amino acid transport
JRU67_RS13380	COG0402	S-adenosylhomocysteine deaminase activity
JRU67_RS13385	COG1012	belongs to the aldehyde dehydrogenase family
JRU67_RS13390	COG0531	amino acid
JRU67_RS13395	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JRU67_RS13400	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JRU67_RS13440	COG1028	Short-chain dehydrogenase reductase Sdr
JRU67_RS13445	COG1312	Catalyzes the dehydration of D-mannonate
JRU67_RS13455	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JRU67_RS13460	COG0800	Aldolase
JRU67_RS13465	COG1414	Transcriptional regulator
JRU67_RS13470	COG2808	Putative FMN-binding domain
JRU67_RS13475	COG0583	DNA-binding transcription factor activity
JRU67_RS13520	COG4607	ABC-type enterochelin transport system periplasmic component
JRU67_RS13525	COG3708	Transcriptional regulator
JRU67_RS13525	COG2207	Transcriptional regulator
JRU67_RS13540	COG2213	PTS system mannitol-specific
JRU67_RS13545	COG3711	transcriptional antiterminator
JRU67_RS13555	COG0246	Mannitol dehydrogenase
JRU67_RS13580	COG0596	Alpha beta hydrolase
JRU67_RS13590	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JRU67_RS13595	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JRU67_RS13600	COG0018	arginyl-trna synthetase
JRU67_RS13615	COG1078	dGTPase activity
JRU67_RS13650	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JRU67_RS13660	COG4844	belongs to the
JRU67_RS13665	COG0095	Lipoate-protein ligase
JRU67_RS13695	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JRU67_RS13705	COG2011	ABC-type metal ion transport system permease component
JRU67_RS13720	COG0786	glutamate:sodium symporter activity
JRU67_RS13725	COG0531	amino acid
JRU67_RS13730	COG2363	Small membrane protein
JRU67_RS13740	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
JRU67_RS13755	COG0363	glucosamine-6-phosphate deaminase activity
JRU67_RS13760	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
JRU67_RS13765	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JRU67_RS13765	COG2190	(PTS) system
JRU67_RS13765	COG1263	PTS System
JRU67_RS13770	COG1737	Transcriptional regulator
JRU67_RS13780	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JRU67_RS13785	COG1469	GTP cyclohydrolase I activity
JRU67_RS13790	COG0431	NADPH-dependent FMN reductase
JRU67_RS13795	COG0561	phosphatase activity
JRU67_RS13805	COG1428	Deoxynucleoside kinase
JRU67_RS13810	COG1428	Deoxynucleoside kinase
JRU67_RS13820	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JRU67_RS13825	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JRU67_RS13835	COG1473	amidohydrolase
JRU67_RS13840	COG1473	amidohydrolase
JRU67_RS13845	COG1473	amidohydrolase
JRU67_RS13850	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JRU67_RS13855	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JRU67_RS13860	COG0049	tRNA binding
JRU67_RS13865	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
JRU67_RS13875	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JRU67_RS13880	COG0085	RNA polymerase activity
JRU67_RS13885	COG2813	Specifically methylates the guanine in position
JRU67_RS13890	COG0222	ribosome binding
JRU67_RS13895	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JRU67_RS13900	COG0081	regulation of translation
JRU67_RS13905	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
JRU67_RS13920	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JRU67_RS13935	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JRU67_RS13940	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
JRU67_RS13945	COG0215	cysteine-tRNA ligase activity
JRU67_RS13970	COG4956	integral membrane protein (PIN domain superfamily)
JRU67_RS13975	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JRU67_RS13980	COG0542	response to heat
JRU67_RS13985	COG3869	Catalyzes the specific phosphorylation of arginine residues in
JRU67_RS13990	COG3880	PFAM UvrB UvrC protein
JRU67_RS13995	COG4463	regulation of RNA biosynthetic process
JRU67_RS14000	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JRU67_RS14005	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
JRU67_RS14010	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
JRU67_RS14015	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JRU67_RS14020	COG1289	transmembrane transporter activity
JRU67_RS14110	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JRU67_RS14130	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
JRU67_RS14135	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JRU67_RS14150	COG1098	S1 RNA binding domain
JRU67_RS14160	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
JRU67_RS14165	COG3956	TIGRFAM MazG family protein
JRU67_RS14170	COG2244	polysaccharide biosynthetic process
JRU67_RS14175	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JRU67_RS14180	COG0193	aminoacyl-tRNA hydrolase activity
JRU67_RS14190	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
JRU67_RS14195	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JRU67_RS14200	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JRU67_RS14205	COG2088	sporulation resulting in formation of a cellular spore
JRU67_RS14210	COG0251	oxidation-reduction process
JRU67_RS14215	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JRU67_RS14220	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
JRU67_RS14225	COG4466	Protein conserved in bacteria
JRU67_RS14235	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
JRU67_RS14240	COG0084	hydrolase, TatD family'
JRU67_RS14245	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JRU67_RS14245	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JRU67_RS14250	COG2002	toxin-antitoxin pair type II binding
JRU67_RS14255	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
JRU67_RS14260	COG2827	Endonuclease containing a URI domain
JRU67_RS14265	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
JRU67_RS14275	COG1774	PSP1 C-terminal conserved region
JRU67_RS14280	COG0470	DNA polymerase III
JRU67_RS14285	COG3870	Protein conserved in bacteria
JRU67_RS14295	COG1982	Orn Lys Arg decarboxylase major
JRU67_RS14320	COG4667	esterase of the alpha-beta hydrolase superfamily
JRU67_RS14330	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JRU67_RS14335	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JRU67_RS14350	COG2188	Transcriptional regulator
JRU67_RS14355	COG0366	Alpha amylase catalytic
JRU67_RS14360	COG1263	PTS System
JRU67_RS14360	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JRU67_RS14370	COG0791	NLP P60 protein
JRU67_RS14375	COG4948	Mandelate Racemase Muconate Lactonizing
JRU67_RS14380	COG1619	proteins homologs of microcin C7 resistance protein MccF
JRU67_RS14390	COG0493	'glutamate synthase
JRU67_RS14395	COG0067	glutamate synthase
JRU67_RS14395	COG0070	glutamate synthase
JRU67_RS14395	COG0069	glutamate synthase activity
JRU67_RS14400	COG0583	DNA-binding transcription factor activity
JRU67_RS14405	COG2094	Belongs to the DNA glycosylase MPG family
JRU67_RS14420	COG0346	lactoylglutathione lyase activity
JRU67_RS14430	COG2814	Major facilitator Superfamily
JRU67_RS14440	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JRU67_RS14455	COG2076	Multidrug Resistance protein
JRU67_RS14460	COG2076	Multidrug Resistance protein
JRU67_RS14495	COG3328	transposase activity
JRU67_RS14525	COG1674	ftsk spoiiie
JRU67_RS14530	COG2946	Replication initiation factor
JRU67_RS14575	COG0791	NLP P60 protein
JRU67_RS14575	COG0741	lytic transglycosylase activity
JRU67_RS14625	COG0582	viral genome integration into host DNA
JRU67_RS14630	COG0519	Catalyzes the synthesis of GMP from XMP
JRU67_RS14630	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JRU67_RS14635	COG0516	GMP reductase activity
JRU67_RS14635	COG0517	IMP dehydrogenase activity
JRU67_RS14640	COG2233	PERMEase
JRU67_RS14645	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JRU67_RS14660	COG2070	2-Nitropropane dioxygenase
JRU67_RS14665	COG0778	Nitroreductase
JRU67_RS14670	COG0733	neurotransmitter:sodium symporter activity
JRU67_RS14675	COG0471	metal ion transport
JRU67_RS14690	COG1072	(Pantothenic acid kinase))
JRU67_RS14695	COG0384	phenazine biosynthesis protein PhzF
JRU67_RS14730	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JRU67_RS14740	COG0360	Binds together with S18 to 16S ribosomal RNA
JRU67_RS14745	COG0012	GTP binding
JRU67_RS14750	COG4481	Protein conserved in bacteria
JRU67_RS14755	COG0668	transmembrane transport
JRU67_RS14760	COG1475	DNA binding
JRU67_RS14765	COG0626	cystathionine gamma-synthase activity
JRU67_RS14770	COG0626	cystathionine gamma-synthase activity
JRU67_RS14775	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
JRU67_RS14775	COG0646	methionine synthase
JRU67_RS14780	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JRU67_RS14790	COG1966	Carbon starvation protein
JRU67_RS14800	COG1475	DNA binding
JRU67_RS14805	COG0357	Ribosomal RNA small subunit methyltransferase G
JRU67_RS14810	COG0445	tRNA wobble uridine modification
JRU67_RS14815	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JRU67_RS14825	COG0594	ribonuclease P activity
JRU67_RS14840	COG1192	Involved in chromosome partitioning
JRU67_RS14950	COG0741	lytic transglycosylase activity
JRU67_RS14950	COG0791	NLP P60 protein
JRU67_RS15095	COG2249	NAD(P)H dehydrogenase (quinone) activity
JRU67_RS15100	COG0477	Major facilitator Superfamily
JRU67_RS15115	COG0488	(ABC) transporter