locus-tag	class	description
JTZ62_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JTZ62_RS00010	COG0592	DNA-directed DNA polymerase activity
JTZ62_RS00020	COG4152	abc transporter atp-binding protein
JTZ62_RS00025	COG1668	transmembrane transport
JTZ62_RS00030	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JTZ62_RS00035	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
JTZ62_RS00040	COG2501	S4 domain
JTZ62_RS00045	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JTZ62_RS00055	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JTZ62_RS00060	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
JTZ62_RS00070	COG2986	histidine ammonia-lyase
JTZ62_RS00080	COG1228	amidohydrolase
JTZ62_RS00085	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JTZ62_RS00105	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JTZ62_RS00115	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
JTZ62_RS00120	COG0359	binds to the 23S rRNA
JTZ62_RS00125	COG0305	Participates in initiation and elongation during chromosome replication
JTZ62_RS00130	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JTZ62_RS00135	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JTZ62_RS00155	COG5002	protein histidine kinase activity
JTZ62_RS00170	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
JTZ62_RS00175	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
JTZ62_RS00210	COG1280	lysine exporter protein (LysE YggA)
JTZ62_RS00225	COG1063	alcohol dehydrogenase
JTZ62_RS00230	COG0693	protein deglycase activity
JTZ62_RS00235	COG1063	alcohol dehydrogenase
JTZ62_RS00240	COG3328	transposase activity
JTZ62_RS00245	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JTZ62_RS00260	COG0702	epimerase
JTZ62_RS00265	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
JTZ62_RS00300	COG0415	Belongs to the DNA photolyase family
JTZ62_RS00340	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JTZ62_RS00360	COG1063	alcohol dehydrogenase
JTZ62_RS00380	COG1595	DNA-templated transcription, initiation
JTZ62_RS00405	COG0415	Belongs to the DNA photolyase family
JTZ62_RS00415	COG1064	alcohol dehydrogenase
JTZ62_RS00425	COG2814	Major facilitator Superfamily
JTZ62_RS00450	COG1609	Transcriptional regulator
JTZ62_RS00465	COG2160	L-arabinose isomerase activity
JTZ62_RS00480	COG0640	Transcriptional regulator
JTZ62_RS00545	COG0717	Belongs to the dCTP deaminase family
JTZ62_RS00560	COG2146	nitrite reductase [NAD(P)H] activity
JTZ62_RS00565	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JTZ62_RS00580	COG1288	antiporter activity
JTZ62_RS00585	COG3711	transcriptional antiterminator
JTZ62_RS00590	COG1263	PTS System
JTZ62_RS00590	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JTZ62_RS00595	COG2723	6-phospho-beta-galactosidase activity
JTZ62_RS00605	COG2814	Major facilitator Superfamily
JTZ62_RS00615	COG2508	Transcriptional regulator
JTZ62_RS00620	COG1953	Uracil, thiamine, allantoin
JTZ62_RS00625	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JTZ62_RS00630	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JTZ62_RS00640	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JTZ62_RS00645	COG3257	ureidoglycine aminohydrolase activity
JTZ62_RS00650	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
JTZ62_RS00655	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
JTZ62_RS00660	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
JTZ62_RS00665	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
JTZ62_RS00680	COG2807	transmembrane transport
JTZ62_RS00685	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
JTZ62_RS00710	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JTZ62_RS00735	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JTZ62_RS00740	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JTZ62_RS00750	COG1609	Transcriptional regulator
JTZ62_RS00755	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JTZ62_RS00760	COG2610	gluconate transmembrane transporter activity
JTZ62_RS00775	COG0454	-acetyltransferase
JTZ62_RS00780	COG0556	nucleotide-excision repair
JTZ62_RS00785	COG0494	nUDIX hydrolase
JTZ62_RS00790	COG3290	protein histidine kinase activity
JTZ62_RS00795	COG4565	transcriptional regulatory protein
JTZ62_RS00800	COG3493	citrate carrier protein
JTZ62_RS00815	COG1473	amidohydrolase
JTZ62_RS00820	COG1473	amidohydrolase
JTZ62_RS00825	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
JTZ62_RS00835	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JTZ62_RS00840	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JTZ62_RS00845	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JTZ62_RS00850	COG0019	diaminopimelate decarboxylase activity
JTZ62_RS00860	COG4264	IucA IucC family
JTZ62_RS00865	COG4264	IucA IucC family
JTZ62_RS00875	COG0702	epimerase
JTZ62_RS00880	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
JTZ62_RS00890	COG1114	Component of the transport system for branched-chain amino acids
JTZ62_RS00900	COG0183	Belongs to the thiolase family
JTZ62_RS00905	COG3425	synthase
JTZ62_RS00910	COG0477	Major facilitator Superfamily
JTZ62_RS00915	COG0584	glycerophosphoryl diester phosphodiesterase
JTZ62_RS00920	COG0789	Transcriptional regulator
JTZ62_RS00940	COG2207	Transcriptional regulator
JTZ62_RS00940	COG4753	response regulator
JTZ62_RS00945	COG2271	Major facilitator Superfamily
JTZ62_RS00950	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JTZ62_RS00975	COG1846	Transcriptional regulator
JTZ62_RS00990	COG0531	amino acid
JTZ62_RS01000	COG1028	Short-chain dehydrogenase reductase Sdr
JTZ62_RS01005	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
JTZ62_RS01010	COG0157	Belongs to the NadC ModD family
JTZ62_RS01015	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
JTZ62_RS01025	COG1827	regulation of RNA biosynthetic process
JTZ62_RS01035	COG1609	Transcriptional regulator
JTZ62_RS01040	COG1028	Short-chain dehydrogenase reductase Sdr
JTZ62_RS01050	COG1653	transport
JTZ62_RS01055	COG1175	transmembrane transport
JTZ62_RS01060	COG0395	ABC-type sugar transport system, permease component
JTZ62_RS01065	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JTZ62_RS01075	COG0596	Alpha beta hydrolase
JTZ62_RS01085	COG0154	amidase activity
JTZ62_RS01090	COG3842	ATPase activity
JTZ62_RS01095	COG2318	DinB family
JTZ62_RS01100	COG2851	Citrate transporter
JTZ62_RS01105	COG1054	Belongs to the UPF0176 family
JTZ62_RS01125	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JTZ62_RS01145	COG0083	homoserine kinase activity
JTZ62_RS01150	COG3386	PFAM SMP-30 Gluconolaconase
JTZ62_RS01155	COG1304	FMN binding
JTZ62_RS01175	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JTZ62_RS01180	COG1028	Short-chain dehydrogenase reductase Sdr
JTZ62_RS01190	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JTZ62_RS01190	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JTZ62_RS01190	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JTZ62_RS01195	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JTZ62_RS01195	COG3711	transcriptional antiterminator
JTZ62_RS01205	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JTZ62_RS01220	COG0579	oxidoreductase
JTZ62_RS01230	COG0318	PFAM AMP-dependent synthetase and ligase
JTZ62_RS01235	COG1960	acyl-CoA dehydrogenase activity
JTZ62_RS01240	COG1024	Enoyl-CoA hydratase
JTZ62_RS01240	COG1250	3-hydroxyacyl-CoA dehydrogenase
JTZ62_RS01245	COG0183	Belongs to the thiolase family
JTZ62_RS01250	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JTZ62_RS01255	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JTZ62_RS01260	COG3002	Belongs to the UPF0753 family
JTZ62_RS01265	COG0288	reversible hydration of carbon dioxide
JTZ62_RS01270	COG5609	conserved protein (DUF2294)
JTZ62_RS01275	COG1283	sodium-dependent phosphate transmembrane transporter activity
JTZ62_RS01280	COG0673	inositol 2-dehydrogenase activity
JTZ62_RS01290	COG0673	inositol 2-dehydrogenase activity
JTZ62_RS01310	COG2226	methyltransferase
JTZ62_RS01315	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
JTZ62_RS01330	COG0733	neurotransmitter:sodium symporter activity
JTZ62_RS01335	COG0583	DNA-binding transcription factor activity
JTZ62_RS01340	COG1380	Effector of murein hydrolase LrgA
JTZ62_RS01345	COG1346	cytolysis
JTZ62_RS01355	COG0175	sulfate reduction
JTZ62_RS01360	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JTZ62_RS01365	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JTZ62_RS01385	COG0730	response to heat
JTZ62_RS01390	COG2046	Belongs to the sulfate adenylyltransferase family
JTZ62_RS01395	COG0529	Catalyzes the synthesis of activated sulfate
JTZ62_RS01400	COG1510	regulation of RNA biosynthetic process
JTZ62_RS01405	COG1012	belongs to the aldehyde dehydrogenase family
JTZ62_RS01420	COG0659	secondary active sulfate transmembrane transporter activity
JTZ62_RS01445	COG3732	PTS system glucitol sorbitol-specific
JTZ62_RS01450	COG1063	alcohol dehydrogenase
JTZ62_RS01455	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JTZ62_RS01475	COG1247	-acetyltransferase
JTZ62_RS01485	COG0668	transmembrane transport
JTZ62_RS01490	COG2851	Citrate transporter
JTZ62_RS01495	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
JTZ62_RS01510	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
JTZ62_RS01515	COG1113	amino acid transport
JTZ62_RS01520	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
JTZ62_RS01530	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JTZ62_RS01540	COG0477	Major facilitator Superfamily
JTZ62_RS01545	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JTZ62_RS01565	COG2205	protein histidine kinase activity
JTZ62_RS01570	COG0745	RESPONSE REGULATOR receiver
JTZ62_RS01575	COG2311	Membrane
JTZ62_RS01590	COG3961	Belongs to the TPP enzyme family
JTZ62_RS01595	COG3684	Belongs to the aldolase LacD family
JTZ62_RS01600	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JTZ62_RS01600	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JTZ62_RS01600	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JTZ62_RS01630	COG1063	alcohol dehydrogenase
JTZ62_RS01640	COG1063	alcohol dehydrogenase
JTZ62_RS01645	COG3775	system Galactitol-specific IIC component
JTZ62_RS01650	COG3414	Phosphotransferase system galactitol-specific IIB component
JTZ62_RS01665	COG0531	amino acid
JTZ62_RS01675	COG1464	Belongs to the NlpA lipoprotein family
JTZ62_RS01680	COG2271	Major facilitator Superfamily
JTZ62_RS01705	COG0531	amino acid
JTZ62_RS01710	COG2130	NADP-dependent
JTZ62_RS01725	COG2188	Transcriptional regulator
JTZ62_RS01730	COG2222	sugar isomerase
JTZ62_RS01735	COG1105	Belongs to the carbohydrate kinase PfkB family
JTZ62_RS01740	COG3684	Belongs to the aldolase LacD family
JTZ62_RS01750	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JTZ62_RS01755	COG3715	PTS system
JTZ62_RS01760	COG3716	PTS system mannose fructose sorbose family IID component
JTZ62_RS01780	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
JTZ62_RS01785	COG4932	domain protein
JTZ62_RS01785	COG3266	domain, Protein
JTZ62_RS01785	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
JTZ62_RS01800	COG1609	Transcriptional regulator
JTZ62_RS01805	COG0366	Alpha amylase catalytic
JTZ62_RS01820	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
JTZ62_RS01840	COG1316	TRANSCRIPTIONal
JTZ62_RS01850	COG3001	Fructosamine kinase
JTZ62_RS01855	COG0662	Cupin 2, conserved barrel domain protein
JTZ62_RS01860	COG2807	transmembrane transport
JTZ62_RS01865	COG1113	amino acid transport
JTZ62_RS01875	COG3620	sequence-specific DNA binding
JTZ62_RS01895	COG0488	(ABC) transporter
JTZ62_RS01920	COG2084	Dehydrogenase
JTZ62_RS01930	COG2610	gluconate transmembrane transporter activity
JTZ62_RS01945	COG4336	lyase activity
JTZ62_RS01950	COG3275	phosphorelay sensor kinase activity
JTZ62_RS01955	COG3279	Response regulator of the LytR AlgR family
JTZ62_RS01960	COG1380	Effector of murein hydrolase LrgA
JTZ62_RS01965	COG1346	cytolysis
JTZ62_RS01975	COG3844	kynureninase activity
JTZ62_RS01980	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
JTZ62_RS01995	COG3639	organic phosphonate transmembrane transporter activity
JTZ62_RS02000	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
JTZ62_RS02010	COG0737	Belongs to the 5'-nucleotidase family
JTZ62_RS02015	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JTZ62_RS02025	COG2188	Transcriptional regulator
JTZ62_RS02030	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JTZ62_RS02030	COG1263	PTS System
JTZ62_RS02030	COG2190	(PTS) system
JTZ62_RS02035	COG2723	6-phospho-beta-galactosidase activity
JTZ62_RS02070	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
JTZ62_RS02075	COG1280	lysine exporter protein (LysE YggA)
JTZ62_RS02080	COG1132	(ABC) transporter
JTZ62_RS02085	COG1132	(ABC) transporter
JTZ62_RS02095	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
JTZ62_RS02100	COG3189	MarR family transcriptional regulator
JTZ62_RS02105	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JTZ62_RS02110	COG2022	thiamine diphosphate biosynthetic process
JTZ62_RS02120	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JTZ62_RS02125	COG0352	thiamine-phosphate diphosphorylase activity
JTZ62_RS02175	COG3279	Response regulator of the LytR AlgR family
JTZ62_RS02185	COG1733	regulation of RNA biosynthetic process
JTZ62_RS02190	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
JTZ62_RS02205	COG1380	Effector of murein hydrolase LrgA
JTZ62_RS02215	COG1278	Cold shock
JTZ62_RS02225	COG0833	amino acid
JTZ62_RS02230	COG2040	homocysteine
JTZ62_RS02235	COG1012	belongs to the aldehyde dehydrogenase family
JTZ62_RS02240	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JTZ62_RS02250	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JTZ62_RS02255	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
JTZ62_RS02260	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JTZ62_RS02290	COG0656	L-ascorbic acid biosynthetic process
JTZ62_RS02295	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
JTZ62_RS02300	COG3759	membrane
JTZ62_RS02305	COG2409	Drug exporters of the RND superfamily
JTZ62_RS02315	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
JTZ62_RS02325	COG1737	Transcriptional regulator
JTZ62_RS02335	COG1316	TRANSCRIPTIONal
JTZ62_RS02340	COG2207	Transcriptional regulator
JTZ62_RS02360	COG0582	viral genome integration into host DNA
JTZ62_RS02365	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JTZ62_RS02365	COG2111	Na H antiporter
JTZ62_RS02370	COG2111	Na H antiporter
JTZ62_RS02375	COG1006	Multisubunit Na H antiporter MnhC subunit
JTZ62_RS02385	COG1863	multisubunit Na H antiporter MnhE subunit
JTZ62_RS02390	COG2212	antiporter activity
JTZ62_RS02395	COG1320	monovalent cation:proton antiporter activity
JTZ62_RS02405	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JTZ62_RS02415	COG1321	iron dependent repressor
JTZ62_RS02430	COG1132	(ABC) transporter
JTZ62_RS02435	COG1620	l-lactate permease
JTZ62_RS02440	COG0039	L-malate dehydrogenase activity
JTZ62_RS02445	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JTZ62_RS02450	COG1120	ATPase activity
JTZ62_RS02455	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JTZ62_RS02460	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JTZ62_RS02475	COG1302	Protein conserved in bacteria
JTZ62_RS02480	COG2814	Major facilitator Superfamily
JTZ62_RS02485	COG3314	Sporulation integral membrane protein YlbJ
JTZ62_RS02490	COG2329	Antibiotic biosynthesis monooxygenase
JTZ62_RS02495	COG0300	oxidoreductase activity
JTZ62_RS02510	COG2962	Rard protein
JTZ62_RS02525	COG1988	membrane-bound metal-dependent
JTZ62_RS02540	COG1272	protein, Hemolysin III
JTZ62_RS02555	COG1574	metal-dependent hydrolase with the TIM-barrel fold
JTZ62_RS02570	COG2814	Major facilitator Superfamily
JTZ62_RS02575	COG0489	protein tyrosine kinase activity
JTZ62_RS02580	COG2194	sulfuric ester hydrolase activity
JTZ62_RS02645	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JTZ62_RS02655	COG1937	Protein conserved in bacteria
JTZ62_RS02660	COG2217	Heavy metal translocating P-type atpase
JTZ62_RS02665	COG0586	Pfam SNARE associated Golgi protein
JTZ62_RS02670	COG0456	acetyltransferase
JTZ62_RS02675	COG2514	catechol 2,3-dioxygenase activity
JTZ62_RS02680	COG1119	ATPase activity
JTZ62_RS02685	COG0561	phosphatase activity
JTZ62_RS02705	COG0702	epimerase
JTZ62_RS02725	COG0640	Transcriptional regulator
JTZ62_RS02740	COG0477	Major facilitator Superfamily
JTZ62_RS02760	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JTZ62_RS02770	COG2205	protein histidine kinase activity
JTZ62_RS02775	COG1136	(ABC) transporter
JTZ62_RS02780	COG0577	efflux transmembrane transporter activity
JTZ62_RS02785	COG1392	Phosphate transport regulator
JTZ62_RS02790	COG0306	phosphate transporter
JTZ62_RS02795	COG1388	LysM domain
JTZ62_RS02795	COG3942	CHAP domain
JTZ62_RS02800	COG0670	Belongs to the BI1 family
JTZ62_RS02805	COG0217	transcriptional regulatory protein
JTZ62_RS02815	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JTZ62_RS02830	COG1566	PFAM secretion protein HlyD family protein
JTZ62_RS02835	COG2814	Major facilitator Superfamily
JTZ62_RS02850	COG0583	DNA-binding transcription factor activity
JTZ62_RS02855	COG2258	MOSC domain
JTZ62_RS02865	COG2839	Protein conserved in bacteria
JTZ62_RS02870	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JTZ62_RS02880	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JTZ62_RS02885	COG1447	Phosphotransferase system cellobiose-specific component IIA
JTZ62_RS02890	COG4221	oxidoreductase activity
JTZ62_RS02895	COG0788	formyltetrahydrofolate deformylase activity
JTZ62_RS02900	COG0598	Magnesium transport protein CorA
JTZ62_RS02905	COG1940	carbohydrate kinase activity
JTZ62_RS02920	COG0778	Nitroreductase
JTZ62_RS02930	COG2814	Major facilitator Superfamily
JTZ62_RS02935	COG1733	regulation of RNA biosynthetic process
JTZ62_RS02940	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
JTZ62_RS02965	COG1757	Na H antiporter
JTZ62_RS02970	COG0004	ammonium transporteR
JTZ62_RS02975	COG1473	amidohydrolase
JTZ62_RS02985	COG2814	Major facilitator Superfamily
JTZ62_RS02990	COG0753	catalase activity
JTZ62_RS03005	COG3048	D-serine ammonia-lyase activity
JTZ62_RS03010	COG1966	Carbon starvation protein
JTZ62_RS03015	COG3383	formate dehydrogenase (NAD+) activity
JTZ62_RS03035	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JTZ62_RS03045	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JTZ62_RS03050	COG2011	ABC-type metal ion transport system permease component
JTZ62_RS03055	COG1464	Belongs to the NlpA lipoprotein family
JTZ62_RS03070	COG3942	CHAP domain
JTZ62_RS03075	COG1757	Na H antiporter
JTZ62_RS03080	COG3942	CHAP domain
JTZ62_RS03140	COG1131	(ABC) transporter
JTZ62_RS03145	COG1823	symporter activity
JTZ62_RS03150	COG1960	acyl-CoA dehydrogenase activity
JTZ62_RS03155	COG0697	spore germination
JTZ62_RS03160	COG2832	Protein of unknown function (DUF454)
JTZ62_RS03165	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JTZ62_RS03170	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JTZ62_RS03180	COG2186	Transcriptional regulator
JTZ62_RS03185	COG2186	Transcriptional regulator
JTZ62_RS03195	COG1268	BioY protein
JTZ62_RS03205	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
JTZ62_RS03220	COG4149	molybdate abc transporter
JTZ62_RS03225	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
JTZ62_RS03230	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
JTZ62_RS03235	COG1140	nitrate reductase beta subunit
JTZ62_RS03240	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
JTZ62_RS03245	COG2181	nitrate reductase activity
JTZ62_RS03255	COG4585	Histidine kinase
JTZ62_RS03260	COG2197	response regulator
JTZ62_RS03265	COG2223	nitrite transmembrane transporter activity
JTZ62_RS03270	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JTZ62_RS03275	COG0521	Mo-molybdopterin cofactor biosynthetic process
JTZ62_RS03280	COG0315	cyclic pyranopterin monophosphate synthase activity
JTZ62_RS03285	COG0303	'Molybdopterin
JTZ62_RS03290	COG1763	Mo-molybdopterin cofactor biosynthetic process
JTZ62_RS03305	COG0746	molybdenum cofactor guanylyltransferase activity
JTZ62_RS03310	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JTZ62_RS03315	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JTZ62_RS03320	COG2814	Major facilitator Superfamily
JTZ62_RS03330	COG2348	transferase activity, transferring amino-acyl groups
JTZ62_RS03335	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JTZ62_RS03340	COG0436	Aminotransferase
JTZ62_RS03355	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JTZ62_RS03370	COG4975	Glucose uptake
JTZ62_RS03385	COG2252	PERMEase
JTZ62_RS03395	COG0051	transcription antitermination factor activity, RNA binding
JTZ62_RS03400	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JTZ62_RS03405	COG0088	Forms part of the polypeptide exit tunnel
JTZ62_RS03410	COG0089	rRNA binding
JTZ62_RS03415	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JTZ62_RS03420	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JTZ62_RS03425	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
JTZ62_RS03430	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JTZ62_RS03435	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
JTZ62_RS03440	COG0255	Belongs to the universal ribosomal protein uL29 family
JTZ62_RS03450	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JTZ62_RS03455	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
JTZ62_RS03460	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
JTZ62_RS03465	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JTZ62_RS03470	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JTZ62_RS03475	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JTZ62_RS03480	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
JTZ62_RS03485	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JTZ62_RS03490	COG1841	ribosomal large subunit assembly
JTZ62_RS03500	COG0201	protein transport
JTZ62_RS03515	COG0257	Belongs to the bacterial ribosomal protein bL36 family
JTZ62_RS03520	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JTZ62_RS03530	COG0202	RNA polymerase activity
JTZ62_RS03535	COG0203	ribosomal protein L17
JTZ62_RS03540	COG1122	ATPase activity
JTZ62_RS03555	COG0101	tRNA pseudouridine synthase activity
JTZ62_RS03560	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JTZ62_RS03565	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
JTZ62_RS03570	COG1011	Hydrolase
JTZ62_RS03580	COG3655	Transcriptional regulator
JTZ62_RS03585	COG0346	lactoylglutathione lyase activity
JTZ62_RS03610	COG0604	alcohol dehydrogenase
JTZ62_RS03615	COG1511	domain protein
JTZ62_RS03625	COG3842	ATPase activity
JTZ62_RS03630	COG2182	Extracellular solute-binding protein
JTZ62_RS03635	COG1175	transmembrane transport
JTZ62_RS03640	COG3833	ABC-type maltose transport systems, permease component
JTZ62_RS03645	COG1609	Transcriptional regulator
JTZ62_RS03650	COG0366	Alpha amylase catalytic
JTZ62_RS03655	COG2376	Dihydroxyacetone kinase
JTZ62_RS03660	COG1461	Dihydroxyacetone kinase
JTZ62_RS03665	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
JTZ62_RS03670	COG2186	Transcriptional regulator
JTZ62_RS03675	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
JTZ62_RS03680	COG1482	cell wall glycoprotein biosynthetic process
JTZ62_RS03690	COG1388	LysM domain
JTZ62_RS03690	COG3942	CHAP domain
JTZ62_RS03700	COG1115	amino acid carrier protein
JTZ62_RS03710	COG1757	Na H antiporter
JTZ62_RS03720	COG1609	Transcriptional regulator
JTZ62_RS03725	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JTZ62_RS03730	COG1869	D-ribose catabolic process
JTZ62_RS03735	COG1129	ABC transporter
JTZ62_RS03740	COG1172	Belongs to the binding-protein-dependent transport system permease family
JTZ62_RS03745	COG1879	ABC-type sugar transport system periplasmic component
JTZ62_RS03750	COG0783	Belongs to the Dps family
JTZ62_RS03755	COG0277	FAD linked oxidase domain protein
JTZ62_RS03760	COG0247	lactate metabolic process
JTZ62_RS03765	COG0813	purine-nucleoside phosphorylase activity
JTZ62_RS03770	COG2390	Transcriptional regulator
JTZ62_RS03775	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JTZ62_RS03785	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
JTZ62_RS03795	COG1854	S-ribosylhomocysteine lyase activity
JTZ62_RS03800	COG0456	acetyltransferase
JTZ62_RS03800	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
JTZ62_RS03840	COG5146	pantothenate kinase activity
JTZ62_RS03845	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JTZ62_RS03850	COG4589	Belongs to the CDS family
JTZ62_RS03870	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JTZ62_RS03875	COG3343	RNA polymerase activity
JTZ62_RS03880	COG0504	CTP synthase activity
JTZ62_RS03885	COG4821	SIS domain
JTZ62_RS03895	COG0191	fructose-bisphosphate aldolase activity
JTZ62_RS03900	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JTZ62_RS03910	COG1012	belongs to the aldehyde dehydrogenase family
JTZ62_RS03915	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
JTZ62_RS03920	COG0254	rRNA binding
JTZ62_RS03925	COG1435	thymidine kinase activity
JTZ62_RS03935	COG2890	protein-(glutamine-N5) methyltransferase activity
JTZ62_RS03940	COG0009	L-threonylcarbamoyladenylate synthase
JTZ62_RS03945	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JTZ62_RS03950	COG0698	ribose 5-phosphate isomerase
JTZ62_RS03955	COG4475	Protein of unknown function (DUF436)
JTZ62_RS03960	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JTZ62_RS03965	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JTZ62_RS03970	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
JTZ62_RS03980	COG0356	it plays a direct role in the translocation of protons across the membrane
JTZ62_RS03985	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JTZ62_RS03990	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JTZ62_RS03995	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JTZ62_RS04000	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JTZ62_RS04005	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JTZ62_RS04010	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JTZ62_RS04035	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JTZ62_RS04045	COG0629	single-stranded DNA binding
JTZ62_RS04050	COG1388	LysM domain
JTZ62_RS04060	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
JTZ62_RS04065	COG0352	thiamine-phosphate diphosphorylase activity
JTZ62_RS04070	COG0706	membrane insertase activity
JTZ62_RS04075	COG1418	mRNA catabolic process
JTZ62_RS04080	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JTZ62_RS04090	COG0772	Belongs to the SEDS family
JTZ62_RS04095	COG1181	Belongs to the D-alanine--D-alanine ligase family
JTZ62_RS04100	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JTZ62_RS04110	COG0513	Belongs to the DEAD box helicase family
JTZ62_RS04150	COG2208	phosphoserine phosphatase activity
JTZ62_RS04165	COG1191	sigma factor activity
JTZ62_RS04170	COG2183	response to ionizing radiation
JTZ62_RS04175	COG3091	SprT-like family
JTZ62_RS04205	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JTZ62_RS04215	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JTZ62_RS04220	COG0473	3-isopropylmalate dehydrogenase activity
JTZ62_RS04225	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JTZ62_RS04230	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
JTZ62_RS04240	COG0028	Belongs to the TPP enzyme family
JTZ62_RS04245	COG0129	dihydroxy-acid dehydratase activity
JTZ62_RS04250	COG0802	atpase or kinase
JTZ62_RS04255	COG1214	PFAM Peptidase M22, glycoprotease
JTZ62_RS04260	COG0456	acetyltransferase
JTZ62_RS04265	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JTZ62_RS04280	COG0488	(ABC) transporter
JTZ62_RS04285	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
JTZ62_RS04290	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JTZ62_RS04295	COG0805	protein transport
JTZ62_RS04320	COG0860	N-Acetylmuramoyl-L-alanine amidase
JTZ62_RS04320	COG1388	LysM domain
JTZ62_RS04355	COG2433	Pfam Transposase IS66
JTZ62_RS04365	COG0739	heme binding
JTZ62_RS04365	COG0741	lytic transglycosylase activity
JTZ62_RS04365	COG1196	nuclear chromosome segregation
JTZ62_RS04370	COG0582	viral genome integration into host DNA
JTZ62_RS04435	COG4373	Mu-like prophage FluMu protein gp28
JTZ62_RS04475	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
JTZ62_RS04680	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
JTZ62_RS04785	COG1690	Belongs to the RtcB family
JTZ62_RS04840	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
JTZ62_RS04895	COG0587	DNA-directed DNA polymerase activity
JTZ62_RS05090	COG1780	Probably involved in ribonucleotide reductase function
JTZ62_RS05100	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JTZ62_RS05105	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JTZ62_RS05150	COG0425	Belongs to the sulfur carrier protein TusA family
JTZ62_RS05155	COG1609	Transcriptional regulator
JTZ62_RS05160	COG1621	beta-fructofuranosidase activity
JTZ62_RS05190	COG0459	protein refolding
JTZ62_RS05195	COG0582	viral genome integration into host DNA
JTZ62_RS05285	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JTZ62_RS05310	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JTZ62_RS05315	COG1131	(ABC) transporter
JTZ62_RS05330	COG1131	(ABC) transporter
JTZ62_RS05345	COG1473	amidohydrolase
JTZ62_RS05355	COG1070	Carbohydrate kinase
JTZ62_RS05360	COG2610	gluconate transmembrane transporter activity
JTZ62_RS05365	COG2223	nitrite transmembrane transporter activity
JTZ62_RS05395	COG0385	Bile acid
JTZ62_RS05435	COG4512	PFAM Accessory gene regulator B
JTZ62_RS05440	COG2706	6-phosphogluconolactonase activity
JTZ62_RS05445	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JTZ62_RS05450	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JTZ62_RS05455	COG0390	transport system, permease component
JTZ62_RS05460	COG1012	belongs to the aldehyde dehydrogenase family
JTZ62_RS05465	COG0673	inositol 2-dehydrogenase activity
JTZ62_RS05480	COG1227	inorganic diphosphatase activity
JTZ62_RS05485	COG1335	isochorismatase
JTZ62_RS05500	COG0077	Prephenate dehydratase
JTZ62_RS05515	COG0107	imidazoleglycerol-phosphate synthase activity
JTZ62_RS05520	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
JTZ62_RS05525	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
JTZ62_RS05530	COG0131	Imidazoleglycerol-phosphate dehydratase
JTZ62_RS05535	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JTZ62_RS05540	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JTZ62_RS05545	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
JTZ62_RS05550	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
JTZ62_RS05555	COG0477	Major facilitator Superfamily
JTZ62_RS05560	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JTZ62_RS05565	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
JTZ62_RS05570	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
JTZ62_RS05580	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JTZ62_RS05585	COG4496	protein, YerC YecD
JTZ62_RS05590	COG1876	peptidase activity
JTZ62_RS05595	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
JTZ62_RS05600	COG0210	DNA helicase
JTZ62_RS05605	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JTZ62_RS05610	COG4851	CamS sex pheromone cAM373 precursor
JTZ62_RS05615	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JTZ62_RS05620	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JTZ62_RS05630	COG0154	amidase activity
JTZ62_RS05635	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JTZ62_RS05640	COG0433	COG0433 Predicted ATPase
JTZ62_RS05645	COG1597	lipid kinase activity
JTZ62_RS05665	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JTZ62_RS05680	COG1528	Iron-storage protein
JTZ62_RS05695	COG4129	membrane
JTZ62_RS05700	COG0024	Methionine aminopeptidase
JTZ62_RS05720	COG2197	response regulator
JTZ62_RS05725	COG0288	reversible hydration of carbon dioxide
JTZ62_RS05730	COG1295	ribonuclease BN
JTZ62_RS05745	COG4840	Belongs to the UPF0435 family
JTZ62_RS05750	COG2309	aminopeptidase activity
JTZ62_RS05760	COG1607	acyl-coa hydrolase
JTZ62_RS05765	COG0535	radical SAM domain protein
JTZ62_RS05775	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JTZ62_RS05780	COG0693	protein deglycase activity
JTZ62_RS05790	COG0028	Belongs to the TPP enzyme family
JTZ62_RS05795	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JTZ62_RS05800	COG2137	regulation of response to DNA damage stimulus
JTZ62_RS05810	COG1134	teichoic acid transport
JTZ62_RS05820	COG1988	membrane-bound metal-dependent
JTZ62_RS05825	COG1194	a g-specific adenine glycosylase
JTZ62_RS05830	COG3557	Belongs to the UPF0374 family
JTZ62_RS05845	COG4129	membrane
JTZ62_RS05850	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JTZ62_RS05855	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JTZ62_RS05865	COG0735	belongs to the Fur family
JTZ62_RS06020	COG1609	Transcriptional regulator
JTZ62_RS06050	COG1904	glucuronate isomerase
JTZ62_RS06065	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JTZ62_RS06070	COG0765	amino acid transport
JTZ62_RS06075	COG1126	abc transporter atp-binding protein
JTZ62_RS06080	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
JTZ62_RS06085	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
JTZ62_RS06090	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
JTZ62_RS06095	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JTZ62_RS06100	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
JTZ62_RS06110	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
JTZ62_RS06115	COG0363	glucosamine-6-phosphate deaminase activity
JTZ62_RS06125	COG0114	fumarate hydratase activity
JTZ62_RS06135	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
JTZ62_RS06140	COG0564	pseudouridine synthase activity
JTZ62_RS06150	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
JTZ62_RS06170	COG2203	Gaf domain
JTZ62_RS06170	COG4585	Histidine kinase
JTZ62_RS06175	COG2197	response regulator
JTZ62_RS06190	COG4399	Belongs to the UPF0754 family
JTZ62_RS06195	COG3679	Belongs to the UPF0342 family
JTZ62_RS06200	COG0420	3'-5' exonuclease activity
JTZ62_RS06210	COG3481	metal-dependent phosphohydrolase, HD sub domain
JTZ62_RS06215	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JTZ62_RS06225	COG1846	Transcriptional regulator
JTZ62_RS06235	COG0537	adenosine 5'-monophosphoramidase activity
JTZ62_RS06240	COG1131	(ABC) transporter
JTZ62_RS06250	COG2329	Antibiotic biosynthesis monooxygenase
JTZ62_RS06255	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
JTZ62_RS06260	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
JTZ62_RS06265	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
JTZ62_RS06320	COG1051	belongs to the nudix hydrolase family
JTZ62_RS06335	COG2176	DNA-directed DNA polymerase activity
JTZ62_RS06340	COG0697	spore germination
JTZ62_RS06345	COG0456	acetyltransferase
JTZ62_RS06355	COG2814	Major facilitator Superfamily
JTZ62_RS06380	COG0494	nUDIX hydrolase
JTZ62_RS06385	COG1506	peptidase
JTZ62_RS06390	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
JTZ62_RS06395	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JTZ62_RS06405	COG1012	belongs to the aldehyde dehydrogenase family
JTZ62_RS06410	COG0656	L-ascorbic acid biosynthetic process
JTZ62_RS06415	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JTZ62_RS06435	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JTZ62_RS06440	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JTZ62_RS06460	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JTZ62_RS06485	COG1595	DNA-templated transcription, initiation
JTZ62_RS06530	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JTZ62_RS06530	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JTZ62_RS06535	COG0307	riboflavin synthase, alpha
JTZ62_RS06565	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
JTZ62_RS06570	COG2267	carboxylic ester hydrolase activity
JTZ62_RS06580	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
JTZ62_RS06585	COG1242	4 iron, 4 sulfur cluster binding
JTZ62_RS06590	COG2814	Major facilitator Superfamily
JTZ62_RS06595	COG0495	leucyl-tRNA aminoacylation
JTZ62_RS06600	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JTZ62_RS06605	COG2081	HI0933 family
JTZ62_RS06610	COG2244	polysaccharide biosynthetic process
JTZ62_RS06615	COG1187	pseudouridine synthase activity
JTZ62_RS06635	COG0510	thiamine kinase activity
JTZ62_RS06640	COG0220	tRNA (guanine-N7-)-methyltransferase activity
JTZ62_RS06645	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JTZ62_RS06650	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
JTZ62_RS06660	COG1363	Peptidase, m42
JTZ62_RS06665	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JTZ62_RS06670	COG0765	amino acid transport
JTZ62_RS06675	COG1126	abc transporter atp-binding protein
JTZ62_RS06685	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JTZ62_RS06690	COG4848	Belongs to the UPF0354 family
JTZ62_RS06695	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JTZ62_RS06700	COG1674	ftsk spoiiie
JTZ62_RS06705	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JTZ62_RS06710	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
JTZ62_RS06715	COG4980	gas vesicle protein
JTZ62_RS06720	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
JTZ62_RS06720	COG1605	Chorismate mutase
JTZ62_RS06725	COG1609	Transcriptional regulator
JTZ62_RS06730	COG0123	including yeast histone deacetylase and acetoin utilization protein
JTZ62_RS06735	COG0517	IMP dehydrogenase activity
JTZ62_RS06740	COG0454	-acetyltransferase
JTZ62_RS06745	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JTZ62_RS06750	COG2759	Belongs to the formate--tetrahydrofolate ligase family
JTZ62_RS06755	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JTZ62_RS06760	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JTZ62_RS06765	COG1704	LemA family
JTZ62_RS06775	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JTZ62_RS06780	COG0204	Acyl-transferase
JTZ62_RS06795	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JTZ62_RS06805	COG1764	response to oxidative stress
JTZ62_RS06815	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JTZ62_RS06820	COG1956	GAF domain-containing protein
JTZ62_RS06825	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
JTZ62_RS06830	COG1104	cysteine desulfurase activity
JTZ62_RS06835	COG0301	tRNA thio-modification
JTZ62_RS06845	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JTZ62_RS06850	COG0616	signal peptide processing
JTZ62_RS06855	COG1714	RDD family
JTZ62_RS06860	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
JTZ62_RS06865	COG0827	DNA restriction-modification system
JTZ62_RS06870	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JTZ62_RS06875	COG0589	response to stress
JTZ62_RS06880	COG0686	Belongs to the AlaDH PNT family
JTZ62_RS06890	COG3142	Participates in the control of copper homeostasis
JTZ62_RS06895	COG0006	proline dipeptidase activity
JTZ62_RS06900	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
JTZ62_RS06905	COG4109	DRTGG domain
JTZ62_RS06915	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
JTZ62_RS06920	COG0587	DNA-directed DNA polymerase activity
JTZ62_RS06925	COG0281	malic enzyme
JTZ62_RS06930	COG1725	Transcriptional regulator
JTZ62_RS06935	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
JTZ62_RS06940	COG0825	malonyl-CoA metabolic process
JTZ62_RS06945	COG0205	6-phosphofructokinase activity
JTZ62_RS06950	COG0469	pyruvate kinase activity
JTZ62_RS06955	COG1113	amino acid transport
JTZ62_RS06960	COG0372	Belongs to the citrate synthase family
JTZ62_RS06965	COG0538	isocitrate dehydrogenase activity
JTZ62_RS06975	COG0745	RESPONSE REGULATOR receiver
JTZ62_RS06980	COG5002	protein histidine kinase activity
JTZ62_RS06985	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JTZ62_RS06985	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JTZ62_RS06990	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
JTZ62_RS06995	COG0237	dephospho-CoA kinase activity
JTZ62_RS07000	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JTZ62_RS07010	COG3611	Membrane attachment protein
JTZ62_RS07015	COG1484	DNA-dependent DNA replication
JTZ62_RS07025	COG0833	amino acid
JTZ62_RS07030	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
JTZ62_RS07035	COG0291	Belongs to the bacterial ribosomal protein bL35 family
JTZ62_RS07040	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
JTZ62_RS07045	COG4112	unkown
JTZ62_RS07055	COG0544	peptidyl-prolyl cis-trans isomerase activity
JTZ62_RS07060	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JTZ62_RS07065	COG0218	Necessary for normal cell division and for the maintenance of normal septation
JTZ62_RS07070	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
JTZ62_RS07075	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JTZ62_RS07080	COG0181	hydroxymethylbilane synthase activity
JTZ62_RS07090	COG0113	porphobilinogen synthase activity
JTZ62_RS07095	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JTZ62_RS07110	COG0285	dihydrofolate synthase activity
JTZ62_RS07115	COG1288	antiporter activity
JTZ62_RS07120	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
JTZ62_RS07205	COG1132	(ABC) transporter
JTZ62_RS07210	COG1132	(ABC) transporter
JTZ62_RS07220	COG1792	Involved in formation and maintenance of cell shape
JTZ62_RS07230	COG0261	This protein binds to 23S rRNA in the presence of protein L20
JTZ62_RS07235	COG2868	ribosomal protein
JTZ62_RS07240	COG0211	Belongs to the bacterial ribosomal protein bL27 family
JTZ62_RS07250	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JTZ62_RS07255	COG4492	Belongs to the UPF0735 family
JTZ62_RS07260	COG0632	four-way junction helicase activity
JTZ62_RS07265	COG2255	four-way junction helicase activity
JTZ62_RS07275	COG0343	queuine tRNA-ribosyltransferase activity
JTZ62_RS07280	COG1862	Preprotein translocase
JTZ62_RS07285	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JTZ62_RS07285	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JTZ62_RS07290	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
JTZ62_RS07290	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
JTZ62_RS07300	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JTZ62_RS07310	COG0860	N-Acetylmuramoyl-L-alanine amidase
JTZ62_RS07315	COG0124	histidyl-tRNA synthetase
JTZ62_RS07320	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
JTZ62_RS07330	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
JTZ62_RS07335	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JTZ62_RS07340	COG1959	2 iron, 2 sulfur cluster binding
JTZ62_RS07350	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JTZ62_RS07355	COG0488	(ABC) transporter
JTZ62_RS07360	COG1104	cysteine desulfurase activity
JTZ62_RS07365	COG0482	sulfurtransferase activity
JTZ62_RS07375	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
JTZ62_RS07380	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JTZ62_RS07385	COG4472	Bacterial protein of unknown function (DUF965)
JTZ62_RS07390	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JTZ62_RS07400	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JTZ62_RS07405	COG4122	O-methyltransferase activity
JTZ62_RS07410	COG0826	peptidase U32
JTZ62_RS07415	COG0826	peptidase U32
JTZ62_RS07420	COG0572	uridine kinase
JTZ62_RS07425	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JTZ62_RS07430	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
JTZ62_RS07435	COG1984	allophanate hydrolase subunit 2
JTZ62_RS07445	COG0439	Biotin carboxylase
JTZ62_RS07450	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
JTZ62_RS07455	COG1914	H( )-stimulated, divalent metal cation uptake system
JTZ62_RS07460	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JTZ62_RS07465	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
JTZ62_RS07470	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JTZ62_RS07475	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JTZ62_RS07480	COG1534	Rna-binding protein
JTZ62_RS07485	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JTZ62_RS07490	COG1713	HD superfamily hydrolase involved in NAD metabolism
JTZ62_RS07495	COG0799	negative regulation of ribosome biogenesis
JTZ62_RS07500	COG2226	methyltransferase
JTZ62_RS07505	COG1596	polysaccharide export
JTZ62_RS07505	COG1555	photosystem II stabilization
JTZ62_RS07510	COG2131	deaminase
JTZ62_RS07515	COG0658	competence protein
JTZ62_RS07515	COG2333	competence protein COMEC
JTZ62_RS07525	COG1466	dna polymerase III delta subunit
JTZ62_RS07530	COG0268	Binds directly to 16S ribosomal RNA
JTZ62_RS07535	COG0481	GTPase activity
JTZ62_RS07540	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JTZ62_RS07550	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JTZ62_RS07555	COG0443	Heat shock 70 kDa protein
JTZ62_RS07565	COG2264	protein methyltransferase activity
JTZ62_RS07570	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JTZ62_RS07575	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JTZ62_RS07580	COG0828	Belongs to the bacterial ribosomal protein bS21 family
JTZ62_RS07585	COG1030	water channel activity
JTZ62_RS07590	COG4864	UPF0365 protein
JTZ62_RS07605	COG1702	phosphate starvation-inducible protein PhoH
JTZ62_RS07610	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JTZ62_RS07615	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
JTZ62_RS07620	COG0295	cytidine deaminase activity
JTZ62_RS07630	COG1381	Involved in DNA repair and RecF pathway recombination
JTZ62_RS07635	COG0423	glycine-tRNA ligase activity
JTZ62_RS07640	COG0517	IMP dehydrogenase activity
JTZ62_RS07645	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
JTZ62_RS07650	COG0358	DNA primase activity
JTZ62_RS07655	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JTZ62_RS07660	COG2010	Cytochrome c
JTZ62_RS07665	COG2384	SAM-dependent methyltransferase
JTZ62_RS07670	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JTZ62_RS07675	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
JTZ62_RS07680	COG0513	Belongs to the DEAD box helicase family
JTZ62_RS07685	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
JTZ62_RS07690	COG1121	(ABC) transporter
JTZ62_RS07695	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JTZ62_RS07700	COG0735	belongs to the Fur family
JTZ62_RS07705	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
JTZ62_RS07710	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
JTZ62_RS07720	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JTZ62_RS07725	COG0768	penicillin binding
JTZ62_RS07730	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
JTZ62_RS07735	COG0573	inorganic phosphate transmembrane transporter activity
JTZ62_RS07740	COG0581	inorganic phosphate transmembrane transporter activity
JTZ62_RS07745	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JTZ62_RS07750	COG0704	Plays a role in the regulation of phosphate uptake
JTZ62_RS07755	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JTZ62_RS07760	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JTZ62_RS07765	COG0457	Tetratricopeptide repeat
JTZ62_RS07765	COG0705	Rhomboid family
JTZ62_RS07770	COG4483	Protein conserved in bacteria
JTZ62_RS07775	COG1940	carbohydrate kinase activity
JTZ62_RS07780	COG0011	TIGRFAM Protein of
JTZ62_RS07790	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JTZ62_RS07800	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JTZ62_RS07805	COG1459	type II secretion system
JTZ62_RS07835	COG0404	The glycine cleavage system catalyzes the degradation of glycine
JTZ62_RS07840	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JTZ62_RS07850	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JTZ62_RS07855	COG0095	Lipoate-protein ligase
JTZ62_RS07870	COG0006	proline dipeptidase activity
JTZ62_RS07875	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JTZ62_RS07880	COG0511	ligase activity, forming carbon-carbon bonds
JTZ62_RS07885	COG0439	Biotin carboxylase
JTZ62_RS07890	COG1302	Protein conserved in bacteria
JTZ62_RS07900	COG1570	exodeoxyribonuclease VII activity
JTZ62_RS07915	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
JTZ62_RS07920	COG1438	arginine binding
JTZ62_RS07925	COG0497	DNA recombination
JTZ62_RS07940	COG0280	phosphate acetyltransferase
JTZ62_RS07950	COG3426	butyrate kinase activity
JTZ62_RS07955	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JTZ62_RS07960	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JTZ62_RS07965	COG0022	dehydrogenase e1 component
JTZ62_RS07970	COG0508	dehydrogenase complex catalyzes the overall conversion of
JTZ62_RS07980	COG4129	membrane
JTZ62_RS07990	COG2195	Cleaves the N-terminal amino acid of tripeptides
JTZ62_RS07995	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
JTZ62_RS08000	COG2207	Transcriptional regulator
JTZ62_RS08000	COG1917	Cupin 2, conserved barrel domain protein
JTZ62_RS08005	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JTZ62_RS08010	COG1234	tRNA 3'-trailer cleavage
JTZ62_RS08015	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JTZ62_RS08025	COG0667	Aldo Keto reductase
JTZ62_RS08035	COG0735	belongs to the Fur family
JTZ62_RS08040	COG4974	Belongs to the 'phage' integrase family
JTZ62_RS08045	COG1547	Domain of unknown function (DUF309)
JTZ62_RS08050	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
JTZ62_RS08055	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JTZ62_RS08060	COG1187	pseudouridine synthase activity
JTZ62_RS08065	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JTZ62_RS08070	COG1333	cytochrome c biogenesis protein
JTZ62_RS08075	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JTZ62_RS08080	COG0745	RESPONSE REGULATOR receiver
JTZ62_RS08085	COG5002	protein histidine kinase activity
JTZ62_RS08095	COG1141	Ferredoxin
JTZ62_RS08100	COG4955	Helix-turn-helix domain
JTZ62_RS08105	COG0514	ATP-dependent DNA helicase (RecQ)
JTZ62_RS08120	COG0492	ferredoxin-NADP+ reductase activity
JTZ62_RS08130	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
JTZ62_RS08135	COG0539	negative regulation of cytoplasmic translation
JTZ62_RS08140	COG1160	GTP binding
JTZ62_RS08145	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
JTZ62_RS08170	COG2226	methyltransferase
JTZ62_RS08175	COG0142	geranyltranstransferase activity
JTZ62_RS08180	COG0105	UTP biosynthetic process
JTZ62_RS08185	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
JTZ62_RS08190	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JTZ62_RS08195	COG0457	Tetratricopeptide repeat
JTZ62_RS08210	COG0723	plastoquinol--plastocyanin reductase activity
JTZ62_RS08215	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
JTZ62_RS08230	COG2738	Putative neutral zinc metallopeptidase
JTZ62_RS08235	COG1694	Mazg nucleotide pyrophosphohydrolase
JTZ62_RS08240	COG0438	transferase activity, transferring glycosyl groups
JTZ62_RS08245	COG0617	tRNA 3'-terminal CCA addition
JTZ62_RS08255	COG1199	ATP-dependent helicase activity
JTZ62_RS08255	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JTZ62_RS08265	COG3935	DnaD domain protein
JTZ62_RS08270	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JTZ62_RS08280	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JTZ62_RS08280	COG4499	WXG100 protein secretion system (Wss), protein YukC
JTZ62_RS08285	COG3331	DNA recombination
JTZ62_RS08295	COG4474	Belongs to the UPF0398 family
JTZ62_RS08300	COG3599	regulation of cell shape
JTZ62_RS08310	COG0116	Belongs to the methyltransferase superfamily
JTZ62_RS08315	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JTZ62_RS08325	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
JTZ62_RS08330	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JTZ62_RS08335	COG0328	RNA-DNA hybrid ribonuclease activity
JTZ62_RS08360	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
JTZ62_RS08370	COG1413	lyase activity
JTZ62_RS08395	COG0204	Acyl-transferase
JTZ62_RS08415	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JTZ62_RS08420	COG2190	(PTS) system
JTZ62_RS08425	COG4479	Belongs to the UPF0346 family
JTZ62_RS08430	COG0793	Belongs to the peptidase S41A family
JTZ62_RS08445	COG0671	phosphoesterase, PA-phosphatase related
JTZ62_RS08455	COG5002	protein histidine kinase activity
JTZ62_RS08460	COG0567	Dehydrogenase, E1 component
JTZ62_RS08465	COG0508	dehydrogenase complex catalyzes the overall conversion of
JTZ62_RS08470	COG2267	carboxylic ester hydrolase activity
JTZ62_RS08485	COG0714	Associated with various cellular activities
JTZ62_RS08490	COG4548	von Willebrand factor, type A
JTZ62_RS08495	COG1114	Component of the transport system for branched-chain amino acids
JTZ62_RS08500	COG5505	Protein of unknown function (DUF819)
JTZ62_RS08505	COG3853	Toxic anion resistance protein (TelA)
JTZ62_RS08515	COG1254	Belongs to the acylphosphatase family
JTZ62_RS08550	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JTZ62_RS08555	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JTZ62_RS08560	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JTZ62_RS08565	COG0527	aspartate kinase activity
JTZ62_RS08570	COG0488	(ABC) transporter
JTZ62_RS08575	COG2996	Protein conserved in bacteria
JTZ62_RS08580	COG3711	transcriptional antiterminator
JTZ62_RS08585	COG1447	Phosphotransferase system cellobiose-specific component IIA
JTZ62_RS08590	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JTZ62_RS08590	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JTZ62_RS08595	COG2723	6-phospho-beta-galactosidase activity
JTZ62_RS08600	COG3684	Belongs to the aldolase LacD family
JTZ62_RS08605	COG1105	Belongs to the carbohydrate kinase PfkB family
JTZ62_RS08610	COG1105	Belongs to the carbohydrate kinase PfkB family
JTZ62_RS08615	COG0698	ribose 5-phosphate isomerase
JTZ62_RS08625	COG1349	DNA-binding transcription factor activity
JTZ62_RS08630	COG1164	Oligoendopeptidase f
JTZ62_RS08670	COG0159	tryptophan synthase activity
JTZ62_RS08675	COG0133	tryptophan synthase activity
JTZ62_RS08680	COG0135	phosphoribosylanthranilate isomerase activity
JTZ62_RS08690	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JTZ62_RS08700	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JTZ62_RS08705	COG1363	Peptidase, m42
JTZ62_RS08710	COG0287	Prephenate dehydrogenase
JTZ62_RS08720	COG1476	TRANSCRIPTIONal
JTZ62_RS08725	COG1757	Na H antiporter
JTZ62_RS08730	COG1929	Belongs to the glycerate kinase type-1 family
JTZ62_RS08735	COG0471	metal ion transport
JTZ62_RS08755	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JTZ62_RS08790	COG0586	Pfam SNARE associated Golgi protein
JTZ62_RS08795	COG0583	DNA-binding transcription factor activity
JTZ62_RS08810	COG0628	permease
JTZ62_RS08815	COG1263	PTS System
JTZ62_RS08815	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JTZ62_RS08815	COG2190	(PTS) system
JTZ62_RS08820	COG3711	transcriptional antiterminator
JTZ62_RS08830	COG1115	amino acid carrier protein
JTZ62_RS08835	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JTZ62_RS08845	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
JTZ62_RS08850	COG4841	protein insertion into membrane
JTZ62_RS08855	COG0824	Thioesterase
JTZ62_RS08865	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JTZ62_RS08870	COG1970	mechanosensitive ion channel activity
JTZ62_RS08875	COG1999	signal sequence binding
JTZ62_RS08895	COG4846	Membrane protein involved in cytochrome C biogenesis
JTZ62_RS08900	COG0785	Cytochrome C biogenesis protein
JTZ62_RS08905	COG3763	UPF0154 protein
JTZ62_RS08915	COG4224	UPF0291 protein
JTZ62_RS08925	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JTZ62_RS08935	COG0516	GMP reductase activity
JTZ62_RS08940	COG0803	Belongs to the bacterial solute-binding protein 9 family
JTZ62_RS08945	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JTZ62_RS08950	COG0833	amino acid
JTZ62_RS08965	COG0640	Transcriptional regulator
JTZ62_RS08980	COG0561	phosphatase activity
JTZ62_RS08985	COG0083	homoserine kinase activity
JTZ62_RS08990	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
JTZ62_RS08995	COG0460	homoserine dehydrogenase
JTZ62_RS09000	COG0527	aspartate kinase activity
JTZ62_RS09015	COG2084	Dehydrogenase
JTZ62_RS09030	COG1597	lipid kinase activity
JTZ62_RS09070	COG0110	maltose O-acetyltransferase activity
JTZ62_RS09085	COG0789	Transcriptional regulator
JTZ62_RS09090	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
JTZ62_RS09095	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JTZ62_RS09100	COG0386	Belongs to the glutathione peroxidase family
JTZ62_RS09105	COG1923	regulation of RNA biosynthetic process
JTZ62_RS09110	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JTZ62_RS09115	COG2267	carboxylic ester hydrolase activity
JTZ62_RS09120	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
JTZ62_RS09125	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JTZ62_RS09130	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JTZ62_RS09135	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
JTZ62_RS09140	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JTZ62_RS09145	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JTZ62_RS09155	COG4550	Control of competence regulator ComK, YlbF/YmcA
JTZ62_RS09160	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JTZ62_RS09170	COG1132	(ABC) transporter
JTZ62_RS09175	COG1132	(ABC) transporter
JTZ62_RS09185	COG1013	pyruvate-flavodoxin oxidoreductase activity
JTZ62_RS09190	COG0674	pyruvate-flavodoxin oxidoreductase activity
JTZ62_RS09190	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
JTZ62_RS09195	COG1692	metallophosphoesterase
JTZ62_RS09205	COG0463	Glycosyl transferase, family 2
JTZ62_RS09205	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JTZ62_RS09230	COG0500	methyltransferase
JTZ62_RS09235	COG0561	phosphatase activity
JTZ62_RS09240	COG1917	Cupin 2, conserved barrel domain protein
JTZ62_RS09240	COG2207	Transcriptional regulator
JTZ62_RS09245	COG0697	spore germination
JTZ62_RS09260	COG0596	Alpha beta hydrolase
JTZ62_RS09265	COG3177	Filamentation induced by cAMP protein fic
JTZ62_RS09270	COG1418	mRNA catabolic process
JTZ62_RS09275	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JTZ62_RS09280	COG1546	Belongs to the CinA family
JTZ62_RS09280	COG1058	Belongs to the CinA family
JTZ62_RS09300	COG0300	oxidoreductase activity
JTZ62_RS09305	COG0612	Peptidase, M16
JTZ62_RS09315	COG2188	Transcriptional regulator
JTZ62_RS09325	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JTZ62_RS09330	COG0612	Peptidase, M16
JTZ62_RS09335	COG1185	polyribonucleotide nucleotidyltransferase activity
JTZ62_RS09345	COG0196	riboflavin kinase activity
JTZ62_RS09350	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JTZ62_RS09355	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JTZ62_RS09360	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
JTZ62_RS09365	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JTZ62_RS09365	COG1263	PTS System
JTZ62_RS09390	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JTZ62_RS09395	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JTZ62_RS09400	COG2169	Transcriptional regulator
JTZ62_RS09410	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JTZ62_RS09415	COG1358	cellular component organization or biogenesis
JTZ62_RS09420	COG2740	Nucleic-acid-binding protein implicated in transcription termination
JTZ62_RS09425	COG0195	Participates in both transcription termination and antitermination
JTZ62_RS09430	COG0779	Required for maturation of 30S ribosomal subunits
JTZ62_RS09440	COG0442	prolyl-tRNA aminoacylation
JTZ62_RS09450	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
JTZ62_RS09455	COG4589	Belongs to the CDS family
JTZ62_RS09465	COG0233	cytoplasmic translational termination
JTZ62_RS09470	COG0528	UMP kinase activity
JTZ62_RS09475	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JTZ62_RS09480	COG0052	Belongs to the universal ribosomal protein uS2 family
JTZ62_RS09490	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
JTZ62_RS09495	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
JTZ62_RS09500	COG4974	Belongs to the 'phage' integrase family
JTZ62_RS09505	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
JTZ62_RS09510	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JTZ62_RS09515	COG0758	DNA mediated transformation
JTZ62_RS09525	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
JTZ62_RS09530	COG0045	succinate-CoA ligase (ADP-forming) activity
JTZ62_RS09535	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JTZ62_RS09540	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JTZ62_RS09545	COG0463	Glycosyl transferase, family 2
JTZ62_RS09550	COG4485	Bacterial membrane protein, YfhO
JTZ62_RS09555	COG0335	large ribosomal subunit rRNA binding
JTZ62_RS09560	COG0336	Belongs to the RNA methyltransferase TrmD family
JTZ62_RS09570	COG1837	Belongs to the UPF0109 family
JTZ62_RS09575	COG0228	four-way junction DNA binding
JTZ62_RS09580	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JTZ62_RS09585	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
JTZ62_RS09590	COG0552	protein localization to endoplasmic reticulum
JTZ62_RS09595	COG1196	nuclear chromosome segregation
JTZ62_RS09615	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JTZ62_RS09630	COG0416	fatty acid biosynthetic process
JTZ62_RS09635	COG1349	DNA-binding transcription factor activity
JTZ62_RS09640	COG3764	Sortase (surface protein transpeptidase)
JTZ62_RS09645	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JTZ62_RS09650	COG1760	l-serine dehydratase
JTZ62_RS09655	COG1760	l-serine dehydratase
JTZ62_RS09665	COG1302	Protein conserved in bacteria
JTZ62_RS09670	COG0227	Belongs to the bacterial ribosomal protein bL28 family
JTZ62_RS09675	COG1564	THIamine pyrophosphokinase
JTZ62_RS09680	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JTZ62_RS09685	COG1162	GTPase activity
JTZ62_RS09690	COG5002	protein histidine kinase activity
JTZ62_RS09690	COG3850	Histidine kinase
JTZ62_RS09695	COG0745	RESPONSE REGULATOR receiver
JTZ62_RS09700	COG2124	cytochrome p450
JTZ62_RS09720	COG0820	rRNA (adenine-C2-)-methyltransferase activity
JTZ62_RS09725	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JTZ62_RS09725	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JTZ62_RS09730	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JTZ62_RS09735	COG0242	peptide deformylase activity
JTZ62_RS09750	COG1686	Belongs to the peptidase S11 family
JTZ62_RS09755	COG4221	oxidoreductase activity
JTZ62_RS09760	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JTZ62_RS09765	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JTZ62_RS09770	COG1758	RNA polymerase activity
JTZ62_RS09790	COG0471	metal ion transport
JTZ62_RS09805	COG0284	orotidine-5'-phosphate decarboxylase activity
JTZ62_RS09810	COG0167	dihydroorotate dehydrogenase activity
JTZ62_RS09815	COG0543	2 iron, 2 sulfur cluster binding
JTZ62_RS09820	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JTZ62_RS09825	COG0505	Belongs to the CarA family
JTZ62_RS09835	COG0540	Belongs to the ATCase OTCase family
JTZ62_RS09845	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JTZ62_RS09850	COG0564	pseudouridine synthase activity
JTZ62_RS09855	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JTZ62_RS09870	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JTZ62_RS09875	COG3599	regulation of cell shape
JTZ62_RS09885	COG0762	integral membrane protein
JTZ62_RS09890	COG1799	cell septum assembly
JTZ62_RS09895	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
JTZ62_RS09900	COG1496	oxidoreductase activity
JTZ62_RS09905	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JTZ62_RS09910	COG0849	cell division
JTZ62_RS09915	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
JTZ62_RS09920	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JTZ62_RS09925	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JTZ62_RS09930	COG0768	penicillin binding
JTZ62_RS09935	COG4839	cell division protein FtsL
JTZ62_RS09940	COG0275	rRNA processing
JTZ62_RS09945	COG2001	Belongs to the MraZ family
JTZ62_RS09950	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
JTZ62_RS09955	COG0454	-acetyltransferase
JTZ62_RS09965	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JTZ62_RS09970	COG0366	Alpha amylase catalytic
JTZ62_RS09985	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
JTZ62_RS09985	COG0456	acetyltransferase
JTZ62_RS10010	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JTZ62_RS10020	COG1846	Transcriptional regulator
JTZ62_RS10025	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JTZ62_RS10030	COG1053	succinate dehydrogenase
JTZ62_RS10035	COG2009	succinate dehydrogenase
JTZ62_RS10040	COG0322	excinuclease ABC activity
JTZ62_RS10045	COG3118	belongs to the thioredoxin family
JTZ62_RS10050	COG1024	Enoyl-CoA hydratase
JTZ62_RS10060	COG1796	DNA polymerase
JTZ62_RS10060	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JTZ62_RS10070	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
JTZ62_RS10075	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JTZ62_RS10080	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JTZ62_RS10080	COG0072	phenylalanine-tRNA ligase activity
JTZ62_RS10085	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JTZ62_RS10090	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JTZ62_RS10110	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JTZ62_RS10115	COG0742	ribosomal rna small subunit methyltransferase
JTZ62_RS10130	COG0584	glycerophosphoryl diester phosphodiesterase
JTZ62_RS10135	COG3679	Belongs to the UPF0342 family
JTZ62_RS10140	COG2340	Cysteine-rich secretory protein family
JTZ62_RS10160	COG3336	cytochrome c oxidase
JTZ62_RS10185	COG0109	protoheme IX farnesyltransferase activity
JTZ62_RS10190	COG1612	heme a metabolic process
JTZ62_RS10200	COG0772	Belongs to the SEDS family
JTZ62_RS10205	COG4838	Belongs to the UPF0358 family
JTZ62_RS10215	COG4896	Protein conserved in bacteria
JTZ62_RS10225	COG1217	gtp-binding protein TYPA
JTZ62_RS10235	COG0483	inositol monophosphate 1-phosphatase activity
JTZ62_RS10255	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
JTZ62_RS10260	COG1177	transmembrane transport
JTZ62_RS10265	COG1176	ABC-type spermidine putrescine transport system, permease component I
JTZ62_RS10270	COG3842	ATPase activity
JTZ62_RS10280	COG4476	Belongs to the UPF0223 family
JTZ62_RS10300	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JTZ62_RS10310	COG0242	peptide deformylase activity
JTZ62_RS10320	COG0561	phosphatase activity
JTZ62_RS10325	COG5503	Protein of unknown function (DUF1447)
JTZ62_RS10335	COG0569	domain protein
JTZ62_RS10345	COG1271	oxidase subunit
JTZ62_RS10355	COG1408	metallophosphoesterase
JTZ62_RS10375	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JTZ62_RS10385	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JTZ62_RS10400	COG4172	Belongs to the ABC transporter superfamily
JTZ62_RS10410	COG0151	Belongs to the GarS family
JTZ62_RS10415	COG0138	bifunctional purine biosynthesis protein purh
JTZ62_RS10425	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
JTZ62_RS10440	COG0047	phosphoribosylformylglycinamidine synthase activity
JTZ62_RS10445	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JTZ62_RS10450	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
JTZ62_RS10460	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JTZ62_RS10495	COG3964	amidohydrolase
JTZ62_RS10500	COG1017	nitric oxide dioxygenase activity
JTZ62_RS10500	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JTZ62_RS10505	COG1959	2 iron, 2 sulfur cluster binding
JTZ62_RS10515	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JTZ62_RS10520	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JTZ62_RS10525	COG1845	cytochrome c oxidase, subunit III
JTZ62_RS10530	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
JTZ62_RS10535	COG0813	purine-nucleoside phosphorylase activity
JTZ62_RS10555	COG1134	teichoic acid transport
JTZ62_RS10565	COG1682	transport, permease protein
JTZ62_RS10585	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
JTZ62_RS10600	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JTZ62_RS10600	COG0463	Glycosyl transferase, family 2
JTZ62_RS10610	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JTZ62_RS10615	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JTZ62_RS10615	COG0463	Glycosyl transferase, family 2
JTZ62_RS10620	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
JTZ62_RS10640	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JTZ62_RS10645	COG1682	transport, permease protein
JTZ62_RS10670	COG0183	Belongs to the thiolase family
JTZ62_RS10675	COG0318	PFAM AMP-dependent synthetase and ligase
JTZ62_RS10680	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
JTZ62_RS10685	COG1316	TRANSCRIPTIONal
JTZ62_RS10695	COG2153	protein acetylation
JTZ62_RS10705	COG3594	Acyltransferase
JTZ62_RS10715	COG0436	Aminotransferase
JTZ62_RS10720	COG4187	Peptidase family M20/M25/M40
JTZ62_RS10725	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
JTZ62_RS10730	COG0596	Alpha beta hydrolase
JTZ62_RS10740	COG1169	isochorismate synthase
JTZ62_RS10745	COG1575	Belongs to the MenA family. Type 1 subfamily
JTZ62_RS10810	COG4873	Protein conserved in bacteria
JTZ62_RS10820	COG0737	Belongs to the 5'-nucleotidase family
JTZ62_RS10825	COG3852	Histidine kinase
JTZ62_RS10830	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JTZ62_RS10835	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JTZ62_RS10835	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JTZ62_RS10840	COG0861	Integral membrane protein TerC family
JTZ62_RS10845	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
JTZ62_RS10855	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JTZ62_RS10860	COG1131	(ABC) transporter
JTZ62_RS10875	COG2814	Major facilitator Superfamily
JTZ62_RS10880	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
JTZ62_RS10885	COG2382	esterase
JTZ62_RS10890	COG1115	amino acid carrier protein
JTZ62_RS10895	COG0628	permease
JTZ62_RS10905	COG0475	glutathione-regulated potassium exporter activity
JTZ62_RS10905	COG0569	domain protein
JTZ62_RS10910	COG2239	Acts as a magnesium transporter
JTZ62_RS10915	COG0564	pseudouridine synthase activity
JTZ62_RS10925	COG2357	RelA SpoT domain protein
JTZ62_RS10935	COG4116	CYTH
JTZ62_RS10940	COG2346	COG2346, Truncated hemoglobins
JTZ62_RS10945	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
JTZ62_RS10950	COG1164	Oligoendopeptidase f
JTZ62_RS10960	COG4862	establishment of competence for transformation
JTZ62_RS10965	COG1393	Belongs to the ArsC family
JTZ62_RS10975	COG4166	transmembrane transport
JTZ62_RS10980	COG4166	transmembrane transport
JTZ62_RS10985	COG4166	transmembrane transport
JTZ62_RS10990	COG4166	transmembrane transport
JTZ62_RS10995	COG4608	Belongs to the ABC transporter superfamily
JTZ62_RS11000	COG0444	Belongs to the ABC transporter superfamily
JTZ62_RS11005	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JTZ62_RS11010	COG0601	transmembrane transport
JTZ62_RS11035	COG0542	response to heat
JTZ62_RS11040	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JTZ62_RS11045	COG2151	metal-sulfur cluster biosynthetic enzyme
JTZ62_RS11050	COG0561	phosphatase activity
JTZ62_RS11055	COG1307	EDD domain protein, DegV family
JTZ62_RS11065	COG0366	Alpha amylase catalytic
JTZ62_RS11065	COG1874	Beta-galactosidase
JTZ62_RS11075	COG0179	Fumarylacetoacetate (FAA) hydrolase
JTZ62_RS11080	COG2311	Membrane
JTZ62_RS11090	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
JTZ62_RS11105	COG0398	Pfam SNARE associated Golgi protein
JTZ62_RS11120	COG0137	argininosuccinate synthase activity
JTZ62_RS11125	COG0165	Argininosuccinate lyase
JTZ62_RS11135	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JTZ62_RS11140	COG1012	belongs to the aldehyde dehydrogenase family
JTZ62_RS11145	COG1098	S1 RNA binding domain
JTZ62_RS11155	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JTZ62_RS11165	COG2111	Na H antiporter
JTZ62_RS11165	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JTZ62_RS11170	COG2111	Na H antiporter
JTZ62_RS11185	COG1863	multisubunit Na H antiporter MnhE subunit
JTZ62_RS11190	COG2212	antiporter activity
JTZ62_RS11195	COG1320	monovalent cation:proton antiporter activity
JTZ62_RS11200	COG1028	Short-chain dehydrogenase reductase Sdr
JTZ62_RS11205	COG2050	protein possibly involved in aromatic compounds catabolism
JTZ62_RS11210	COG2056	Na+-H+ antiporter family
JTZ62_RS11215	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JTZ62_RS11225	COG1252	NADH dehydrogenase
JTZ62_RS11230	COG0316	Belongs to the HesB IscA family
JTZ62_RS11235	COG4844	belongs to the
JTZ62_RS11240	COG1252	NADH dehydrogenase
JTZ62_RS11245	COG4837	Protein of unknown function (DUF1462)
JTZ62_RS11250	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
JTZ62_RS11255	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
JTZ62_RS11260	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JTZ62_RS11265	COG1696	Membrane protein involved in D-alanine export
JTZ62_RS11280	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JTZ62_RS11285	COG0647	UMP catabolic process
JTZ62_RS11290	COG2445	Protein of unknown function DUF86
JTZ62_RS11300	COG4470	Protein conserved in bacteria
JTZ62_RS11305	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
JTZ62_RS11310	COG0737	Belongs to the 5'-nucleotidase family
JTZ62_RS11315	COG0730	response to heat
JTZ62_RS11320	COG1801	Protein of unknown function DUF72
JTZ62_RS11325	COG1136	(ABC) transporter
JTZ62_RS11350	COG0860	N-Acetylmuramoyl-L-alanine amidase
JTZ62_RS11350	COG1388	LysM domain
JTZ62_RS11360	COG1395	domain, Protein
JTZ62_RS11375	COG0800	Aldolase
JTZ62_RS11380	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JTZ62_RS11385	COG1028	Short-chain dehydrogenase reductase Sdr
JTZ62_RS11390	COG1940	carbohydrate kinase activity
JTZ62_RS11395	COG2814	Major facilitator Superfamily
JTZ62_RS11405	COG0719	Fe-S assembly protein
JTZ62_RS11410	COG0822	iron-sulfur transferase activity
JTZ62_RS11415	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JTZ62_RS11420	COG0719	Fe-S assembly protein
JTZ62_RS11425	COG0396	ATPase activity
JTZ62_RS11440	COG1464	Belongs to the NlpA lipoprotein family
JTZ62_RS11445	COG2011	ABC-type metal ion transport system permease component
JTZ62_RS11450	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JTZ62_RS11460	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
JTZ62_RS11465	COG0509	glycine decarboxylation via glycine cleavage system
JTZ62_RS11470	COG1393	Belongs to the ArsC family
JTZ62_RS11475	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JTZ62_RS11480	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
JTZ62_RS11480	COG0778	Nitroreductase
JTZ62_RS11485	COG0710	3-dehydroquinate dehydratase activity
JTZ62_RS11505	COG0697	spore germination
JTZ62_RS11510	COG1764	response to oxidative stress
JTZ62_RS11535	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JTZ62_RS11550	COG4166	transmembrane transport
JTZ62_RS11565	COG0523	cobalamin synthesis protein
JTZ62_RS11570	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JTZ62_RS11620	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JTZ62_RS11635	COG0477	Major facilitator Superfamily
JTZ62_RS11650	COG0406	alpha-ribazole phosphatase activity
JTZ62_RS11660	COG1525	nuclease
JTZ62_RS11675	COG1280	lysine exporter protein (LysE YggA)
JTZ62_RS11700	COG1846	Transcriptional regulator
JTZ62_RS11700	COG0456	acetyltransferase
JTZ62_RS11710	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JTZ62_RS11715	COG0730	response to heat
JTZ62_RS11785	COG0456	acetyltransferase
JTZ62_RS11795	COG0604	alcohol dehydrogenase
JTZ62_RS11810	COG4824	toxin secretion phage lysis holin
JTZ62_RS11890	COG4695	Portal protein
JTZ62_RS12050	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
JTZ62_RS12055	COG0557	exoribonuclease II activity
JTZ62_RS12060	COG1647	Serine aminopeptidase, S33
JTZ62_RS12065	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JTZ62_RS12070	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
JTZ62_RS12075	COG0148	phosphopyruvate hydratase activity
JTZ62_RS12085	COG0149	triose-phosphate isomerase activity
JTZ62_RS12090	COG0126	phosphoglycerate kinase activity
JTZ62_RS12110	COG0740	serine-type endopeptidase activity
JTZ62_RS12115	COG1481	regulation of sporulation
JTZ62_RS12125	COG0391	Required for morphogenesis under gluconeogenic growth conditions
JTZ62_RS12130	COG1660	Displays ATPase and GTPase activities
JTZ62_RS12145	COG0110	maltose O-acetyltransferase activity
JTZ62_RS12150	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JTZ62_RS12155	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
JTZ62_RS12185	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JTZ62_RS12190	COG3942	CHAP domain
JTZ62_RS12195	COG2010	Cytochrome c
JTZ62_RS12205	COG0653	protein targeting
JTZ62_RS12210	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JTZ62_RS12215	COG1040	competence protein
JTZ62_RS12220	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
JTZ62_RS12225	COG1307	EDD domain protein, DegV family
JTZ62_RS12235	COG1739	Uncharacterized protein family UPF0029
JTZ62_RS12240	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JTZ62_RS12245	COG2199	diguanylate cyclase activity
JTZ62_RS12250	COG2966	Psort location CytoplasmicMembrane, score
JTZ62_RS12295	COG4607	ABC-type enterochelin transport system periplasmic component
JTZ62_RS12300	COG4604	ABC transporter, ATP-binding protein
JTZ62_RS12305	COG4605	iron ion homeostasis
JTZ62_RS12310	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JTZ62_RS12320	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JTZ62_RS12325	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JTZ62_RS12330	COG1780	Probably involved in ribonucleotide reductase function
JTZ62_RS12340	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
JTZ62_RS12345	COG3104	oligopeptide transport
JTZ62_RS12350	COG3104	oligopeptide transport
JTZ62_RS12355	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
JTZ62_RS12365	COG1174	glycine betaine transport
JTZ62_RS12370	COG1125	glycine betaine transport
JTZ62_RS12370	COG0517	IMP dehydrogenase activity
JTZ62_RS12375	COG0514	ATP-dependent DNA helicase (RecQ)
JTZ62_RS12380	COG0488	(ABC) transporter
JTZ62_RS12390	COG1368	sulfuric ester hydrolase activity
JTZ62_RS12395	COG1984	allophanate hydrolase subunit 2
JTZ62_RS12415	COG0512	Glutamine amidotransferase of anthranilate synthase
JTZ62_RS12425	COG0720	synthase
JTZ62_RS12430	COG0602	queuosine metabolic process
JTZ62_RS12440	COG1695	Transcriptional regulator
JTZ62_RS12460	COG0656	L-ascorbic acid biosynthetic process
JTZ62_RS12465	COG1187	pseudouridine synthase activity
JTZ62_RS12470	COG2814	Major facilitator Superfamily
JTZ62_RS12475	COG1253	flavin adenine dinucleotide binding
JTZ62_RS12480	COG2267	carboxylic ester hydrolase activity
JTZ62_RS12485	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JTZ62_RS12485	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JTZ62_RS12485	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JTZ62_RS12490	COG1105	Belongs to the carbohydrate kinase PfkB family
JTZ62_RS12495	COG1349	DNA-binding transcription factor activity
JTZ62_RS12500	COG1473	amidohydrolase
JTZ62_RS12505	COG4989	oxidoreductase activity
JTZ62_RS12510	COG0523	cobalamin synthesis protein
JTZ62_RS12520	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
JTZ62_RS12525	COG4988	ABC transporter
JTZ62_RS12530	COG1968	undecaprenyl-diphosphatase activity
JTZ62_RS12540	COG1671	Belongs to the UPF0178 family
JTZ62_RS12555	COG1683	Conserved Protein
JTZ62_RS12570	COG1012	belongs to the aldehyde dehydrogenase family
JTZ62_RS12590	COG0025	NhaP-type Na H and K H
JTZ62_RS12615	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JTZ62_RS12620	COG0765	amino acid transport
JTZ62_RS12625	COG0765	amino acid transport
JTZ62_RS12630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JTZ62_RS12635	COG1126	abc transporter atp-binding protein
JTZ62_RS12645	COG0778	Nitroreductase
JTZ62_RS12650	COG1136	(ABC) transporter
JTZ62_RS12655	COG0577	efflux transmembrane transporter activity
JTZ62_RS12665	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
JTZ62_RS12670	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JTZ62_RS12685	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JTZ62_RS12685	COG1263	PTS System
JTZ62_RS12690	COG0010	Belongs to the arginase family
JTZ62_RS12695	COG1914	H( )-stimulated, divalent metal cation uptake system
JTZ62_RS12700	COG1660	Displays ATPase and GTPase activities
JTZ62_RS12730	COG1846	Transcriptional regulator
JTZ62_RS12735	COG2818	Glycosylase
JTZ62_RS12745	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JTZ62_RS12760	COG0667	Aldo Keto reductase
JTZ62_RS12765	COG0492	ferredoxin-NADP+ reductase activity
JTZ62_RS12770	COG2207	Transcriptional regulator
JTZ62_RS12775	COG2271	Major facilitator Superfamily
JTZ62_RS12780	COG3226	Transcriptional regulator
JTZ62_RS12790	COG1253	flavin adenine dinucleotide binding
JTZ62_RS12800	COG2197	response regulator
JTZ62_RS12805	COG4585	Histidine kinase
JTZ62_RS12810	COG0842	Transport permease protein
JTZ62_RS12815	COG1131	(ABC) transporter
JTZ62_RS12825	COG0672	)-iron permease
JTZ62_RS12830	COG2837	iron assimilation
JTZ62_RS12835	COG2822	iron ion transport
JTZ62_RS12850	COG3634	alkyl hydroperoxide reductase activity
JTZ62_RS12860	COG1132	(ABC) transporter
JTZ62_RS12865	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JTZ62_RS12865	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JTZ62_RS12875	COG1447	Phosphotransferase system cellobiose-specific component IIA
JTZ62_RS12880	COG3711	transcriptional antiterminator
JTZ62_RS12880	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JTZ62_RS12885	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JTZ62_RS12890	COG2723	6-phospho-beta-galactosidase activity
JTZ62_RS12900	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JTZ62_RS12905	COG2264	protein methyltransferase activity
JTZ62_RS12910	COG0803	Belongs to the bacterial solute-binding protein 9 family
JTZ62_RS12910	COG3443	Belongs to the bacterial solute-binding protein 9 family
JTZ62_RS12920	COG1136	(ABC) transporter
JTZ62_RS12935	COG4607	ABC-type enterochelin transport system periplasmic component
JTZ62_RS12945	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
JTZ62_RS12950	COG2162	N-hydroxyarylamine O-acetyltransferase activity
JTZ62_RS12960	COG0477	Major facilitator Superfamily
JTZ62_RS12965	COG0477	Major facilitator Superfamily
JTZ62_RS12975	COG3732	PTS system glucitol sorbitol-specific
JTZ62_RS12980	COG3730	PTS system glucitol sorbitol-specific
JTZ62_RS12990	COG3711	transcriptional antiterminator
JTZ62_RS12990	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JTZ62_RS13000	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JTZ62_RS13005	COG0740	serine-type endopeptidase activity
JTZ62_RS13020	COG0400	carboxylic ester hydrolase activity
JTZ62_RS13025	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JTZ62_RS13030	COG0346	lactoylglutathione lyase activity
JTZ62_RS13035	COG1846	Transcriptional regulator
JTZ62_RS13040	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JTZ62_RS13045	COG0626	cystathionine gamma-synthase activity
JTZ62_RS13055	COG0789	Transcriptional regulator
JTZ62_RS13055	COG4978	Transcriptional regulator
JTZ62_RS13075	COG1131	(ABC) transporter
JTZ62_RS13080	COG2188	Transcriptional regulator
JTZ62_RS13090	COG0693	protein deglycase activity
JTZ62_RS13095	COG3173	Aminoglycoside phosphotransferase
JTZ62_RS13120	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JTZ62_RS13125	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JTZ62_RS13135	COG1486	melibiose metabolic process
JTZ62_RS13155	COG1028	Short-chain dehydrogenase reductase Sdr
JTZ62_RS13160	COG4175	Glycine betaine
JTZ62_RS13160	COG0517	IMP dehydrogenase activity
JTZ62_RS13180	COG1388	LysM domain
JTZ62_RS13185	COG2910	NAD(P)H-binding
JTZ62_RS13190	COG1959	2 iron, 2 sulfur cluster binding
JTZ62_RS13225	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
JTZ62_RS13230	COG1902	pentaerythritol trinitrate reductase activity
JTZ62_RS13235	COG3037	sugar-specific permease SgaT UlaA
JTZ62_RS13245	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JTZ62_RS13255	COG2723	6-phospho-beta-galactosidase activity
JTZ62_RS13260	COG2723	6-phospho-beta-galactosidase activity
JTZ62_RS13265	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JTZ62_RS13265	COG1263	PTS System
JTZ62_RS13265	COG2190	(PTS) system
JTZ62_RS13270	COG3711	transcriptional antiterminator
JTZ62_RS13275	COG3239	Fatty acid desaturase
JTZ62_RS13285	COG1363	Peptidase, m42
JTZ62_RS13295	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
JTZ62_RS13300	COG2357	RelA SpoT domain protein
JTZ62_RS13305	COG1486	melibiose metabolic process
JTZ62_RS13310	COG1263	PTS System
JTZ62_RS13310	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JTZ62_RS13315	COG1737	Transcriptional regulator
JTZ62_RS13320	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JTZ62_RS13325	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JTZ62_RS13330	COG1279	arginine transmembrane transporter activity
JTZ62_RS13335	COG0191	fructose-bisphosphate aldolase activity
JTZ62_RS13340	COG0673	inositol 2-dehydrogenase activity
JTZ62_RS13345	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JTZ62_RS13350	COG1082	Xylose isomerase domain protein TIM barrel
JTZ62_RS13355	COG0673	inositol 2-dehydrogenase activity
JTZ62_RS13360	COG3962	Belongs to the TPP enzyme family
JTZ62_RS13365	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JTZ62_RS13380	COG1349	DNA-binding transcription factor activity
JTZ62_RS13390	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JTZ62_RS13390	COG1263	PTS System
JTZ62_RS13395	COG2824	Alkylphosphonate utilization operon protein PhnA
JTZ62_RS13410	COG1131	(ABC) transporter
JTZ62_RS13420	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JTZ62_RS13420	COG3711	transcriptional antiterminator
JTZ62_RS13425	COG2723	6-phospho-beta-galactosidase activity
JTZ62_RS13430	COG1447	Phosphotransferase system cellobiose-specific component IIA
JTZ62_RS13435	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JTZ62_RS13445	COG1113	amino acid transport
JTZ62_RS13455	COG0402	S-adenosylhomocysteine deaminase activity
JTZ62_RS13460	COG1012	belongs to the aldehyde dehydrogenase family
JTZ62_RS13465	COG0531	amino acid
JTZ62_RS13470	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JTZ62_RS13475	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JTZ62_RS13515	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JTZ62_RS13520	COG1136	(ABC) transporter
JTZ62_RS13525	COG0577	efflux transmembrane transporter activity
JTZ62_RS13530	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JTZ62_RS13540	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JTZ62_RS13545	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JTZ62_RS13555	COG3711	transcriptional antiterminator
JTZ62_RS13560	COG1063	alcohol dehydrogenase
JTZ62_RS13570	COG2271	Major facilitator Superfamily
JTZ62_RS13575	COG1028	Short-chain dehydrogenase reductase Sdr
JTZ62_RS13580	COG1312	Catalyzes the dehydration of D-mannonate
JTZ62_RS13585	COG1063	alcohol dehydrogenase
JTZ62_RS13590	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JTZ62_RS13595	COG0800	Aldolase
JTZ62_RS13600	COG1414	Transcriptional regulator
JTZ62_RS13605	COG1846	Transcriptional regulator
JTZ62_RS13615	COG2808	Putative FMN-binding domain
JTZ62_RS13620	COG0583	DNA-binding transcription factor activity
JTZ62_RS13635	COG4876	unkown
JTZ62_RS13640	COG1522	sequence-specific DNA binding
JTZ62_RS13685	COG4607	ABC-type enterochelin transport system periplasmic component
JTZ62_RS13690	COG3708	Transcriptional regulator
JTZ62_RS13690	COG2207	Transcriptional regulator
JTZ62_RS13700	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JTZ62_RS13705	COG0456	acetyltransferase
JTZ62_RS13710	COG0765	amino acid transport
JTZ62_RS13715	COG1126	abc transporter atp-binding protein
JTZ62_RS13720	COG2079	MmgE PrpD family protein
JTZ62_RS13725	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JTZ62_RS13735	COG3711	transcriptional antiterminator
JTZ62_RS13745	COG0246	Mannitol dehydrogenase
JTZ62_RS13780	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JTZ62_RS13785	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JTZ62_RS13790	COG0018	arginyl-trna synthetase
JTZ62_RS13805	COG1078	dGTPase activity
JTZ62_RS13825	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JTZ62_RS13830	COG2188	Transcriptional regulator
JTZ62_RS13835	COG1028	Short-chain dehydrogenase reductase Sdr
JTZ62_RS13865	COG4844	belongs to the
JTZ62_RS13870	COG0095	Lipoate-protein ligase
JTZ62_RS13890	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JTZ62_RS13900	COG2011	ABC-type metal ion transport system permease component
JTZ62_RS13915	COG0786	glutamate:sodium symporter activity
JTZ62_RS13920	COG0531	amino acid
JTZ62_RS13925	COG2363	Small membrane protein
JTZ62_RS13935	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
JTZ62_RS13950	COG0363	glucosamine-6-phosphate deaminase activity
JTZ62_RS13955	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
JTZ62_RS13960	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JTZ62_RS13960	COG2190	(PTS) system
JTZ62_RS13960	COG1263	PTS System
JTZ62_RS13965	COG1737	Transcriptional regulator
JTZ62_RS13975	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JTZ62_RS13980	COG1469	GTP cyclohydrolase I activity
JTZ62_RS13990	COG0431	NADPH-dependent FMN reductase
JTZ62_RS13995	COG0561	phosphatase activity
JTZ62_RS14005	COG1428	Deoxynucleoside kinase
JTZ62_RS14010	COG1428	Deoxynucleoside kinase
JTZ62_RS14020	COG1388	LysM domain
JTZ62_RS14025	COG2608	mercury ion transmembrane transporter activity
JTZ62_RS14035	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JTZ62_RS14040	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JTZ62_RS14050	COG1473	amidohydrolase
JTZ62_RS14055	COG1473	amidohydrolase
JTZ62_RS14060	COG1473	amidohydrolase
JTZ62_RS14065	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JTZ62_RS14070	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JTZ62_RS14075	COG0049	tRNA binding
JTZ62_RS14080	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
JTZ62_RS14090	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JTZ62_RS14095	COG0085	RNA polymerase activity
JTZ62_RS14100	COG2813	Specifically methylates the guanine in position
JTZ62_RS14105	COG0222	ribosome binding
JTZ62_RS14110	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JTZ62_RS14115	COG0081	regulation of translation
JTZ62_RS14120	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
JTZ62_RS14150	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JTZ62_RS14155	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
JTZ62_RS14160	COG0215	cysteine-tRNA ligase activity
JTZ62_RS14185	COG4956	integral membrane protein (PIN domain superfamily)
JTZ62_RS14190	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JTZ62_RS14195	COG0542	response to heat
JTZ62_RS14200	COG3869	Catalyzes the specific phosphorylation of arginine residues in
JTZ62_RS14205	COG3880	PFAM UvrB UvrC protein
JTZ62_RS14210	COG4463	regulation of RNA biosynthetic process
JTZ62_RS14215	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JTZ62_RS14220	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
JTZ62_RS14225	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
JTZ62_RS14230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JTZ62_RS14235	COG1289	transmembrane transporter activity
JTZ62_RS14325	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JTZ62_RS14345	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
JTZ62_RS14350	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JTZ62_RS14365	COG1098	S1 RNA binding domain
JTZ62_RS14375	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
JTZ62_RS14380	COG3956	TIGRFAM MazG family protein
JTZ62_RS14385	COG2244	polysaccharide biosynthetic process
JTZ62_RS14390	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JTZ62_RS14395	COG0193	aminoacyl-tRNA hydrolase activity
JTZ62_RS14405	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JTZ62_RS14410	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JTZ62_RS14415	COG2088	sporulation resulting in formation of a cellular spore
JTZ62_RS14420	COG0251	oxidation-reduction process
JTZ62_RS14425	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JTZ62_RS14430	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
JTZ62_RS14435	COG4466	Protein conserved in bacteria
JTZ62_RS14445	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
JTZ62_RS14450	COG0084	hydrolase, TatD family'
JTZ62_RS14455	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JTZ62_RS14455	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JTZ62_RS14460	COG2002	toxin-antitoxin pair type II binding
JTZ62_RS14465	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
JTZ62_RS14470	COG2827	Endonuclease containing a URI domain
JTZ62_RS14475	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
JTZ62_RS14485	COG1774	PSP1 C-terminal conserved region
JTZ62_RS14490	COG0470	DNA polymerase III
JTZ62_RS14495	COG3870	Protein conserved in bacteria
JTZ62_RS14505	COG1982	Orn Lys Arg decarboxylase major
JTZ62_RS14530	COG4667	esterase of the alpha-beta hydrolase superfamily
JTZ62_RS14540	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JTZ62_RS14545	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JTZ62_RS14560	COG2188	Transcriptional regulator
JTZ62_RS14565	COG0366	Alpha amylase catalytic
JTZ62_RS14570	COG1263	PTS System
JTZ62_RS14570	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JTZ62_RS14580	COG0791	NLP P60 protein
JTZ62_RS14585	COG4948	Mandelate Racemase Muconate Lactonizing
JTZ62_RS14590	COG1619	proteins homologs of microcin C7 resistance protein MccF
JTZ62_RS14600	COG0493	'glutamate synthase
JTZ62_RS14605	COG0067	glutamate synthase
JTZ62_RS14605	COG0069	glutamate synthase activity
JTZ62_RS14605	COG0070	glutamate synthase
JTZ62_RS14610	COG0583	DNA-binding transcription factor activity
JTZ62_RS14615	COG2094	Belongs to the DNA glycosylase MPG family
JTZ62_RS14630	COG0346	lactoylglutathione lyase activity
JTZ62_RS14640	COG2814	Major facilitator Superfamily
JTZ62_RS14650	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JTZ62_RS14665	COG2076	Multidrug Resistance protein
JTZ62_RS14670	COG2076	Multidrug Resistance protein
JTZ62_RS14690	COG1695	Transcriptional regulator
JTZ62_RS14720	COG0346	lactoylglutathione lyase activity
JTZ62_RS14725	COG0400	carboxylic ester hydrolase activity
JTZ62_RS14765	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JTZ62_RS14765	COG0519	Catalyzes the synthesis of GMP from XMP
JTZ62_RS14770	COG0517	IMP dehydrogenase activity
JTZ62_RS14770	COG0516	GMP reductase activity
JTZ62_RS14775	COG2233	PERMEase
JTZ62_RS14780	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JTZ62_RS14795	COG2070	2-Nitropropane dioxygenase
JTZ62_RS14800	COG0778	Nitroreductase
JTZ62_RS14805	COG0733	neurotransmitter:sodium symporter activity
JTZ62_RS14810	COG0471	metal ion transport
JTZ62_RS14825	COG0346	lactoylglutathione lyase activity
JTZ62_RS14830	COG1072	(Pantothenic acid kinase))
JTZ62_RS14840	COG0384	phenazine biosynthesis protein PhzF
JTZ62_RS14855	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JTZ62_RS14865	COG0360	Binds together with S18 to 16S ribosomal RNA
JTZ62_RS14870	COG0012	GTP binding
JTZ62_RS14875	COG4481	Protein conserved in bacteria
JTZ62_RS14880	COG0668	transmembrane transport
JTZ62_RS14885	COG1475	DNA binding
JTZ62_RS14890	COG0626	cystathionine gamma-synthase activity
JTZ62_RS14895	COG0626	cystathionine gamma-synthase activity
JTZ62_RS14900	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
JTZ62_RS14900	COG0646	methionine synthase
JTZ62_RS14905	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JTZ62_RS14915	COG1966	Carbon starvation protein
JTZ62_RS14920	COG1475	DNA binding
JTZ62_RS14925	COG0357	Ribosomal RNA small subunit methyltransferase G
JTZ62_RS14930	COG0445	tRNA wobble uridine modification
JTZ62_RS14935	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JTZ62_RS14945	COG0594	ribonuclease P activity