locus-tag	class	description
HV559_RS00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
HV559_RS00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
HV559_RS00020	ENOG4105N21	Membrane
HV559_RS00030	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
HV559_RS00035	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
HV559_RS00040	ENOG4105CH7	arginosuccinase
HV559_RS00055	ENOG4105CJ2	(LipO)protein
HV559_RS00060	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
HV559_RS00065	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HV559_RS00070	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HV559_RS00075	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HV559_RS00080	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HV559_RS00085	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HV559_RS00090	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
HV559_RS00095	ENOG4105C2W	permease
HV559_RS00110	ENOG4107R11	Transcriptional regulator
HV559_RS00115	ENOG4105PAD	Hydrolase
HV559_RS00120	ENOG4105ETT	transcriptional Regulator, LysR family
HV559_RS00125	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
HV559_RS00135	ENOG4105K59	histidine triad (HIT) protein
HV559_RS00145	ENOG4105K70	DNA-binding protein
HV559_RS00150	ENOG4105R2J	Conserved Protein
HV559_RS00155	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
HV559_RS00160	ENOG4105E07	UPF0149 protein
HV559_RS00175	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
HV559_RS00180	ENOG4105J4Q	Transcriptional regulator
HV559_RS00185	ENOG4105CK7	Sodium proline symporter
HV559_RS00190	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
HV559_RS00195	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
HV559_RS00200	ENOG41082RQ	UPF0102 protein
HV559_RS00205	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
HV559_RS00210	ENOG4105W4M	Transport-associated protein
HV559_RS00215	ENOG4105CWC	Acetylornithine deacetylase
HV559_RS00230	ENOG4105II7	pyrroline-5-carboxylate reductase
HV559_RS00235	ENOG4105D8G	Major Facilitator superfamily
HV559_RS00245	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
HV559_RS00250	ENOG4105CN1	protease
HV559_RS00255	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
HV559_RS00260	ENOG4105EAQ	(twin-arginine translocation) pathway signal
HV559_RS00265	ENOG4105C5X	domain protein
HV559_RS00270	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
HV559_RS00305	ENOG41065U4	response regulator
HV559_RS00310	ENOG4108VVQ	metallophosphoesterase
HV559_RS00315	ENOG4107VZS	Nicotinamide-nucleotide adenylyltransferase
HV559_RS00320	ENOG4105DTN	riboflavin biosynthesis protein ribF
HV559_RS00325	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
HV559_RS00330	ENOG4105JIM	Phosphatidylserine synthase
HV559_RS00335	ENOG4105C2N	RNA methyltransferase TrmH family group 3
HV559_RS00370	ENOG4108JQ5	ABC transporter
HV559_RS00375	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HV559_RS00380	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HV559_RS00385	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
HV559_RS00405	ENOG41061WM	D-Alanyl-D-Alanine
HV559_RS00410	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
HV559_RS00415	ENOG4105C3G	gtp-binding protein
HV559_RS00425	ENOG4105DAA	L-lactate
HV559_RS00430	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
HV559_RS00435	ENOG4107QR9	Iron-sulfur cluster binding protein
HV559_RS00440	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
HV559_RS00445	ENOG4108JQ1	Dehydrogenase
HV559_RS00450	ENOG4105E66	phosphoriboisomerase A
HV559_RS00455	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
HV559_RS00460	ENOG4105C7B	Threonine dehydratase
HV559_RS00465	ENOG4108YZY	peptidylprolyl cis-trans isomerase
HV559_RS00475	ENOG4108R96	Methyltransferase, YaeB family
HV559_RS00480	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
HV559_RS00490	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HV559_RS00495	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
HV559_RS00510	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
HV559_RS00520	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
HV559_RS00525	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
HV559_RS00530	ENOG4105VG0	50S ribosomal protein l34
HV559_RS00540	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
HV559_RS00545	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
HV559_RS00550	ENOG4105WBN	Transcriptional regulator (LacI family
HV559_RS00555	ENOG4108HKT	sucrose-6-phosphate hydrolase
HV559_RS00560	ENOG4105D7K	pfkb domain protein
HV559_RS00570	ENOG4105C5Y	PTS System
HV559_RS00575	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
HV559_RS00580	ENOG4105KZ7	phosphocarrier protein hpr
HV559_RS00585	ENOG4106SMU	thiamine transporter membrane protein
HV559_RS00590	ENOG4107T0D	ABC, transporter
HV559_RS00595	ENOG4105C5Y	PTS System
HV559_RS00600	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
HV559_RS00605	ENOG4105EX9	Membrane
HV559_RS00610	ENOG4105C2I	pirin domain protein
HV559_RS00615	ENOG4105D52	delta-aminolevulinic acid dehydratase
HV559_RS00620	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
HV559_RS00625	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
HV559_RS00630	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
HV559_RS00635	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
HV559_RS00645	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HV559_RS00650	ENOG4107QUT	magnesium and cobalt transport protein CorA
HV559_RS00655	ENOG4108QD1	Membrane
HV559_RS00660	ENOG4105DBV	ornithine carbamoyltransferase
HV559_RS00665	ENOG4105JAB	phenazine biosynthesis protein, phzf family
HV559_RS00670	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
HV559_RS00675	ENOG4105MJ2	Competence protein
HV559_RS00680	ENOG4108X4Q	Hydrolase
HV559_RS00685	ENOG4105QYV	Membrane
HV559_RS00695	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
HV559_RS00700	ENOG4105EAH	synthase
HV559_RS00705	ENOG4105WPN	DNA integration recombination invertion protein
HV559_RS00710	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
HV559_RS00720	ENOG4105CHR	reductase
HV559_RS00725	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
HV559_RS00740	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
HV559_RS00745	ENOG4107S2Z	UPF0761 membrane protein
HV559_RS00775	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
HV559_RS00780	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
HV559_RS00860	ENOG4107R3N	Filamentation induced by cAMP protein fic
HV559_RS00935	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
HV559_RS00940	ENOG4105W8Z	4'-phosphopantetheinyl transferase
HV559_RS00945	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
HV559_RS00950	ENOG4105CUW	cytochrome C-TYPE protein
HV559_RS00955	ENOG4105IYZ	Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity)
HV559_RS00960	ENOG4105GXZ	Ferredoxin-type protein NapH
HV559_RS00965	ENOG4108BGM	Quinol dehydrogenase periplasmic component
HV559_RS00970	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
HV559_RS00975	ENOG41061Q0	Assembly protein for periplasmic nitrate reductase
HV559_RS00985	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
HV559_RS00990	ENOG4105DY8	decarboxylase
HV559_RS00995	ENOG4105M0J	Toxic component of a toxin-antitoxin (TA) module. A
HV559_RS01005	ENOG4108JPW	Aminotransferase
HV559_RS01020	ENOG4105W5Q	DNA repair protein (RadC
HV559_RS01025	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
HV559_RS01035	ENOG4105DFS	Conserved Protein
HV559_RS01045	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
HV559_RS01050	ENOG4105YP7	UPF0270 protein
HV559_RS01055	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
HV559_RS01060	ENOG4105D4A	Cell wall formation (By similarity)
HV559_RS01065	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
HV559_RS01105	ENOG4105C5F	glutamine synthetase
HV559_RS01110	ENOG4105ESV	Glycosyl transferase, family 4
HV559_RS01130	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HV559_RS01160	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
HV559_RS01165	ENOG4108VZM	50s ribosomal protein L10
HV559_RS01170	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
HV559_RS01175	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
HV559_RS01180	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
HV559_RS01185	ENOG4105PM1	preprotein translocase subunit SecE
HV559_RS01205	ENOG4108HHA	Transketolase
HV559_RS01210	ENOG4108IUS	Transketolase
HV559_RS01215	ENOG4105C79	DNA protecting protein DprA
HV559_RS01235	ENOG4106G6Q	Transcriptional regulator
HV559_RS01240	ENOG4105CK1	PTS System
HV559_RS01255	ENOG4108HRG	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity)
HV559_RS01260	ENOG4105CJK	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity)
HV559_RS01265	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
HV559_RS01280	ENOG4105CNN	ABC, transporter
HV559_RS01285	ENOG4105C2J	ABC transporter
HV559_RS01290	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
HV559_RS01295	ENOG4105C26	Dehydrogenase
HV559_RS01300	ENOG4105DH8	myo-inositol catabolism
HV559_RS01320	ENOG4108MJ5	VirK protein
HV559_RS01325	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
HV559_RS01330	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
HV559_RS01340	ENOG4105CEN	a g-specific adenine glycosylase
HV559_RS01345	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
HV559_RS01350	ENOG4105E4C	Lytic transglycosylase catalytic
HV559_RS01375	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HV559_RS01390	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
HV559_RS01395	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
HV559_RS01400	ENOG4105WWK	YheO domain protein
HV559_RS01405	ENOG4108V1T	peptidylprolyl cis-trans isomerase
HV559_RS01410	ENOG4105VRX	Protein slyX homolog
HV559_RS01425	ENOG4105BZW	Glycerate kinase
HV559_RS01440	ENOG4108JQ1	Dehydrogenase
HV559_RS01445	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
HV559_RS01470	ENOG4105F0S	class B acid phosphatase
HV559_RS01490	ENOG41064BZ	L-xylulose 5-phosphate 3-epimerase
HV559_RS01495	ENOG4107R0P	L-ribulose-5-phosphate 4-epimerase
HV559_RS01500	ENOG4105E5Q	amino acid AbC transporter
HV559_RS01510	ENOG4105MVE	transcriptional regulator
HV559_RS01515	ENOG4105ZXK	Dehydrogenase
HV559_RS01520	ENOG4105G63	Type III effector Hrp-dependent
HV559_RS01525	ENOG4105FB2	class II Aldolase
HV559_RS01530	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
HV559_RS01535	ENOG4105EXW	epimerase dehydratase
HV559_RS01540	ENOG4105C6Z	Gluconate
HV559_RS01560	ENOG4105CDA	abc transporter atp-binding protein
HV559_RS01570	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
HV559_RS01575	ENOG410804X	Transcriptional regulator
HV559_RS01580	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
HV559_RS01585	ENOG4105CXY	transporter
HV559_RS01600	ENOG41076KX	Protein of unknown function (DUF1469)
HV559_RS01605	ENOG4105NE1	Conserved Protein
HV559_RS01610	ENOG4105CMG	Carbohydrate kinase
HV559_RS01625	ENOG4107SDZ	Galactoside transport system permease protein mglC
HV559_RS01630	ENOG4105C2J	ABC transporter
HV559_RS01640	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
HV559_RS01645	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HV559_RS01650	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
HV559_RS01655	ENOG4108R66	Conserved Protein
HV559_RS01660	ENOG4105DG4	malate L-lactate dehydrogenase
HV559_RS01665	ENOG4107QWE	)-transporter
HV559_RS01670	ENOG4105E61	Mannitol repressor protein
HV559_RS01680	ENOG4105CTS	PTS system mannitol-specific
HV559_RS01685	ENOG4105C2X	Arabinose 5-phosphate isomerase
HV559_RS01690	ENOG410681U	heavy metal transport detoxification protein
HV559_RS01700	ENOG4108KS2	transglutaminase domain protein
HV559_RS01705	ENOG4105D9R	oxidoreductase
HV559_RS01715	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
HV559_RS01720	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
HV559_RS01725	ENOG4105HDK	L-asparaginase
HV559_RS01750	ENOG4108ETH	Formylglycinamide ribotide synthetase
HV559_RS01755	ENOG4105E4P	ATPase (AAA
HV559_RS01765	ENOG4107EDW	L-fucose operon activator
HV559_RS01770	ENOG4105EHF	Converts the aldose L-fucose into the corresponding ketose L-fuculose (By similarity)
HV559_RS01775	ENOG4105CMG	Carbohydrate kinase
HV559_RS01780	ENOG4105NWF	RbsD or FucU transport
HV559_RS01785	ENOG4107W7X	Aldolase
HV559_RS01790	ENOG4105EDR	glucose galactose transporter
HV559_RS01795	ENOG4105C0A	alcohol dehydrogenase
HV559_RS01800	ENOG4105C26	Dehydrogenase
HV559_RS01805	ENOG4105C1A	potassium transporter peripheral membrane
HV559_RS01810	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
HV559_RS01825	ENOG4105H1G	trap transporter solute receptor taxi family
HV559_RS01835	ENOG4105EM7	Selenocysteine-specific translation elongation factor
HV559_RS01850	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
HV559_RS01875	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
HV559_RS01880	ENOG4105EVU	fructokinase
HV559_RS01885	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HV559_RS01905	ENOG4108MBX	Secretion Protein
HV559_RS01915	ENOG4105QTB	Flavodoxin
HV559_RS01940	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
HV559_RS01950	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
HV559_RS01955	ENOG4105CB5	ATP-dependent DNA helicase recG
HV559_RS01965	ENOG4107QSU	Phosphoglucomutase phosphomannomutase alpha beta alpha domain
HV559_RS01975	ENOG4105K5B	UPF0225 protein
HV559_RS01980	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
HV559_RS01990	ENOG4105C79	DNA protecting protein DprA
HV559_RS02015	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
HV559_RS02035	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HV559_RS02040	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HV559_RS02045	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HV559_RS02050	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
HV559_RS02055	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
HV559_RS02060	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
HV559_RS02075	ENOG4105CU9	asparagine synthetase A
HV559_RS02080	ENOG4108VVK	transcriptional Regulator, AsnC
HV559_RS02095	ENOG4108I5U	Uridine phosphorylase
HV559_RS02100	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
HV559_RS02105	ENOG4107EP5	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
HV559_RS02110	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
HV559_RS02155	ENOG4108W8W	CRISPR-associated RAMP protein, Csm3 family
HV559_RS02175	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
HV559_RS02210	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HV559_RS02215	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
HV559_RS02240	ENOG4105N2G	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HV559_RS02245	ENOG4108V1T	peptidylprolyl cis-trans isomerase
HV559_RS02285	ENOG4105CNU	cell division protein FtsK
HV559_RS02290	ENOG4107R08	Integrase
HV559_RS02305	ENOG4108UHU	Aldolase
HV559_RS02310	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
HV559_RS02320	ENOG4105DMW	Dehydrogenase reductase
HV559_RS02325	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
HV559_RS02330	ENOG41069H7	transport system small permease component
HV559_RS02335	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HV559_RS02345	ENOG4107YCY	Transcriptional regulator
HV559_RS02355	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
HV559_RS02360	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
HV559_RS02365	ENOG4105CJN	penicillin-binding protein
HV559_RS02370	ENOG4105CNI	cell division protein FtsW
HV559_RS02380	ENOG4105DZ1	carboxypeptidase
HV559_RS02400	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
HV559_RS02405	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
HV559_RS02410	ENOG4105DKW	ABC transporter
HV559_RS02420	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
HV559_RS02425	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
HV559_RS02430	ENOG4108RR8	protoporphyrinogen oxidase
HV559_RS02440	ENOG4105CJR	Integral membrane protein (MviN
HV559_RS02450	ENOG4105C94	Transporter
HV559_RS02455	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
HV559_RS02460	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
HV559_RS02465	ENOG4105E33	succinate dehydrogenase
HV559_RS02470	ENOG4108WJH	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
HV559_RS02475	ENOG4108VP9	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
HV559_RS02520	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
HV559_RS02525	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
HV559_RS02530	ENOG4108K3A	Glutathione S-transferase
HV559_RS02535	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
HV559_RS02545	ENOG4105C9Q	fumarate hydratase class II
HV559_RS02560	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
HV559_RS02565	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
HV559_RS02570	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
HV559_RS02575	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HV559_RS02580	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
HV559_RS02585	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
HV559_RS02590	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
HV559_RS02595	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
HV559_RS02600	ENOG41083MP	50s ribosomal protein l29
HV559_RS02605	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
HV559_RS02610	ENOG4105UGU	tonB-dependent Receptor
HV559_RS02635	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
HV559_RS02640	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
HV559_RS02645	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
HV559_RS02650	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
HV559_RS02655	ENOG4105VPB	50S ribosomal protein L30
HV559_RS02660	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
HV559_RS02665	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
HV559_RS02675	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HV559_RS02680	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
HV559_RS02685	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
HV559_RS02690	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HV559_RS02695	ENOG4108ZT0	50S ribosomal protein l17
HV559_RS02700	ENOG4105K5M	30s ribosomal protein S16
HV559_RS02705	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
HV559_RS02710	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
HV559_RS02715	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
HV559_RS02720	ENOG4105EZE	Cupin 4 family protein
HV559_RS02725	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
HV559_RS02730	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
HV559_RS02735	ENOG4108ST3	glycosyltransferase
HV559_RS02740	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
HV559_RS02745	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
HV559_RS02755	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
HV559_RS02760	ENOG41063M6	Cell Division Protein
HV559_RS02765	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
HV559_RS02775	ENOG4105C0P	Mg chelatase subunit ChlI
HV559_RS02780	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
HV559_RS02790	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HV559_RS02795	ENOG410835K	Tripartite ATP-Independent Periplasmic transporter DctQ
HV559_RS02800	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
HV559_RS02805	ENOG4105KZW	UPF0381 protein
HV559_RS02810	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
HV559_RS02815	ENOG41063VX	Inherit from COG: glutaredoxin-related protein
HV559_RS02825	ENOG4105DFS	Conserved Protein
HV559_RS02830	ENOG4105WDY	DNA (cytosine-5-)-methyltransferase
HV559_RS02860	ENOG4105WD1	Membrane
HV559_RS02880	ENOG4108WFC	UPF0438 protein yifE
HV559_RS02885	ENOG410863D	Flavinator of succinate dehydrogenase
HV559_RS02895	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
HV559_RS02900	ENOG4108YZA	Nitrogen regulatory protein pii
HV559_RS02905	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
HV559_RS02910	ENOG4108M1T	Cytochrome c-type biogenesis protein
HV559_RS02915	ENOG4108M1T	Cytochrome c-type biogenesis protein
HV559_RS02920	ENOG4107QX9	Thiol disulfide interChange protein
HV559_RS02965	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
HV559_RS02975	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
HV559_RS02980	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
HV559_RS02990	ENOG4108TZA	Required for optimal enterobactin synthesis. Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules (By similarity)
HV559_RS02995	ENOG4105CQB	FAD linked oxidase domain protein
HV559_RS03005	ENOG4108R9Q	Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain (By similarity)
HV559_RS03010	ENOG4105DAN	ATP-dependent protease
HV559_RS03015	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
HV559_RS03040	ENOG4105DSY	exodeoxyribonuclease V, gamma
HV559_RS03045	ENOG4107QXK	peptidase
HV559_RS03050	ENOG4105DEF	Extracellular solute-binding protein, family 5
HV559_RS03080	ENOG4108JJA	ABC, transporter
HV559_RS03090	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
HV559_RS03100	ENOG4105MJ9	esterase
HV559_RS03120	ENOG4105ERU	peptidase
HV559_RS03135	ENOG4108JQ7	(ABC) transporter
HV559_RS03140	ENOG4105C3U	ABC transporter
HV559_RS03145	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HV559_RS03150	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HV559_RS03155	ENOG4105DEF	Extracellular solute-binding protein, family 5
HV559_RS03160	ENOG4108KZ1	Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity)
HV559_RS03165	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
HV559_RS03170	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
HV559_RS03175	ENOG41060IM	Heme exporter protein
HV559_RS03180	ENOG4105X3C	heme exporter protein
HV559_RS03190	ENOG4105DA4	cytochrome c-type biogenesis protein
HV559_RS03195	ENOG4105WV0	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
HV559_RS03205	ENOG41063ES	
HV559_RS03230	ENOG4105C75	arginyL-tRNA synthetase
HV559_RS03235	ENOG4105NBI	YecM protein
HV559_RS03240	ENOG4108XTF	Outer Membrane Lipoprotein
HV559_RS03245	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
HV559_RS03285	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
HV559_RS03290	ENOG4105RX8	Protein of unknown function (DUF1523)
HV559_RS03295	ENOG4105F8V	Hydrolase, tatD family
HV559_RS03300	ENOG4107QRG	dna polymerase iii
HV559_RS03305	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
HV559_RS03310	ENOG4105HHA	aminodeoxychorismate lyase
HV559_RS03330	ENOG4105F0N	pyrophosphate phospho-hydrolase
HV559_RS03335	ENOG4105D0M	Protease HtpX homolog
HV559_RS03340	ENOG4105C31	Tryptophanyl-tRNA synthetase
HV559_RS03345	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
HV559_RS03355	ENOG4105HF0	Membrane
HV559_RS03360	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
HV559_RS03365	ENOG4108YYH	Nadph-dependent fmn reductase
HV559_RS03370	ENOG4108IPT	Naphthoate synthase
HV559_RS03375	ENOG4105BZ4	penicillin-binding protein
HV559_RS03380	ENOG4108RMU	ferritin dps family protein
HV559_RS03390	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
HV559_RS03400	ENOG4105EI2	Pseudouridine synthase
HV559_RS03405	ENOG4105EEI	dihydropteroate synthase
HV559_RS03410	ENOG4105KUZ	arsenate reductase
HV559_RS03415	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
HV559_RS03420	ENOG4105EEQ	Na H antiporter
HV559_RS03425	ENOG4105CH6	catalase
HV559_RS03445	ENOG4105CFG	Acts as a chaperone (By similarity)
HV559_RS03450	ENOG4108YZA	Nitrogen regulatory protein pii
HV559_RS03455	ENOG4108IA2	Sodium pantothenate symporter
HV559_RS03460	ENOG4105RG0	Membrane
HV559_RS03465	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
HV559_RS03470	ENOG410903C	(LipO)protein
HV559_RS03475	ENOG4105DFU	Cell wall formation (By similarity)
HV559_RS03490	ENOG4105EUR	Domain-Containing protein
HV559_RS03490	ENOG4105EUR	Domain-Containing protein
HV559_RS03490	ENOG4105EUR	Domain-Containing protein
HV559_RS03490	ENOG4105EUR	Domain-Containing protein
HV559_RS03500	ENOG4105EJ2	Transcriptional regulator
HV559_RS03505	ENOG4105C5Q	Transcriptional regulator
HV559_RS03510	ENOG4105D98	threonine synthase
HV559_RS03515	ENOG4108Z5K	methylglyoxal synthase
HV559_RS03520	ENOG4105H2K	paraquat-inducible protein a
HV559_RS03525	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
HV559_RS03540	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
HV559_RS03545	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
HV559_RS03555	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
HV559_RS03560	ENOG4106KVJ	cytochrome C assembly protein
HV559_RS03565	ENOG4108JU6	CBS domain protein
HV559_RS03570	ENOG4105C8J	)-transporter
HV559_RS03580	ENOG41090BQ	Glutaredoxin
HV559_RS03585	ENOG4105C1J	atp-dependent rna helicase
HV559_RS03590	ENOG4108Z33	Thiol disulfide Interchange Protein
HV559_RS03600	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
HV559_RS03610	ENOG4105DSB	aldose 1-epimerase
HV559_RS03615	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HV559_RS03620	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
HV559_RS03625	ENOG41090ED	Protein with unknown function (DUF469)
HV559_RS03630	ENOG4108VIA	integral membrane protein
HV559_RS03635	ENOG4105CDA	abc transporter atp-binding protein
HV559_RS03640	ENOG4105E5Q	amino acid AbC transporter
HV559_RS03645	ENOG4105EAB	amino acid AbC transporter
HV559_RS03650	ENOG4105YK5	50S ribosomal protein L36
HV559_RS03655	ENOG4105NRA	50s ribosomal protein l31 type b
HV559_RS03660	ENOG4105DJV	ribulose-phosphate 3-epimerase
HV559_RS03665	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
HV559_RS03670	ENOG4108R3E	Dna-3-methyladenine glycosylase i
HV559_RS03675	ENOG4108K5P	(LipO)protein
HV559_RS03690	ENOG4108UM1	dedA family
HV559_RS03695	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
HV559_RS03700	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
HV559_RS03705	ENOG4108BMY	protease
HV559_RS03705	ENOG4108BMY	protease
HV559_RS03715	ENOG4108NK4	UPF0266 membrane protein
HV559_RS03720	ENOG4105F3R	pts system mannose fructose sorbose family iid
HV559_RS03725	ENOG4105ETZ	PTS System
HV559_RS03730	ENOG4105DAS	pts system
HV559_RS03735	ENOG4105D9M	gamma-glutamylcysteine synthetase
HV559_RS03745	ENOG4105DJ4	phosphatidylserine decarboxylase
HV559_RS03750	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
HV559_RS03755	ENOG4108UBT	opacity-associated protein
HV559_RS03765	ENOG4105XA0	heptosyltransferase ii
HV559_RS03770	ENOG4105D16	lipopolysaccharide heptosyltransferase i
HV559_RS03775	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
HV559_RS03780	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
HV559_RS03785	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
HV559_RS03795	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
HV559_RS03800	ENOG4107YZP	Rhodanese domain protein
HV559_RS03805	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
HV559_RS03810	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
HV559_RS03815	ENOG4105D7W	serine acetyltransferase
HV559_RS03830	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HV559_RS03845	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
HV559_RS03850	ENOG4105DFA	alanine racemase domain protein
HV559_RS03855	ENOG4105CI3	gtp-binding protein typa
HV559_RS03860	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
HV559_RS03865	ENOG4108WPU	DNA polymerase III subunit psi
HV559_RS03880	ENOG4105CIH	Imidazole acetol-phosphate transaminase
HV559_RS03890	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
HV559_RS03900	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
HV559_RS03920	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
HV559_RS03925	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
HV559_RS03930	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
HV559_RS03935	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
HV559_RS03940	ENOG4105VEJ	Heat shock protein
HV559_RS03945	ENOG4107RK2	ADP-ribose diphosphatase NudE
HV559_RS03955	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
HV559_RS03960	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
HV559_RS03975	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
HV559_RS03985	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
HV559_RS04010	ENOG4107YB6	acetyltransferase, (GNAT) family
HV559_RS04015	ENOG4105MYG	DNA polymerase iii, chi subunit
HV559_RS04020	ENOG4108WZM	domain protein
HV559_RS04030	ENOG4105C03	ribonuclease
HV559_RS04040	ENOG4105E7U	AraC family transcriptional regulator
HV559_RS04045	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
HV559_RS04050	ENOG4105NXV	High-affinity zinc uptake system protein
HV559_RS04060	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
HV559_RS04065	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
HV559_RS04080	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
HV559_RS04090	ENOG4105CJN	penicillin-binding protein
HV559_RS04095	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
HV559_RS04105	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
HV559_RS04110	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
HV559_RS04115	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
HV559_RS04120	ENOG4105CNI	cell division protein FtsW
HV559_RS04125	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
HV559_RS04135	ENOG4105CPF	Cell wall formation (By similarity)
HV559_RS04145	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
HV559_RS04150	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
HV559_RS04155	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HV559_RS04160	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
HV559_RS04200	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
HV559_RS04205	ENOG4105DSJ	YicC domain protein
HV559_RS04210	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
HV559_RS04215	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
HV559_RS04220	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
HV559_RS04225	ENOG4105C2J	ABC transporter
HV559_RS04230	ENOG4105CNN	ABC, transporter
HV559_RS04235	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
HV559_RS04240	ENOG4108RVA	ribokinase
HV559_RS04245	ENOG4105ETE	Transcriptional regulator (LacI family
HV559_RS04250	ENOG4105WH1	Two component transcriptional regulator luxr family
HV559_RS04260	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
HV559_RS04265	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
HV559_RS04270	ENOG4105CE4	GlcNAc 6-P deacetylase
HV559_RS04280	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
HV559_RS04325	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
HV559_RS04335	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
HV559_RS04340	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
HV559_RS04345	ENOG4108YH1	overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7
HV559_RS04355	ENOG4108R99	pseudouridine synthase
HV559_RS04360	ENOG4105E09	nadh pyrophosphatase
HV559_RS04375	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
HV559_RS04400	ENOG4105CD8	aminopeptidase N
HV559_RS04405	ENOG4105PYN	Pyridoxamine 5-phosphate oxidase-related
HV559_RS04420	ENOG4105E0U	tyrosine-specific transport protein
HV559_RS04425	ENOG4108JA2	transcriptioN-repair coupling factor
HV559_RS04465	ENOG4107SRH	Nad-dependent epimerase dehydratase
HV559_RS04470	ENOG4105CC5	ABC transporter
HV559_RS04475	ENOG4105CC5	ABC transporter
HV559_RS04480	ENOG4105DIK	(ABC) transporter
HV559_RS04495	ENOG41090FY	type IV pilus biogenesis stability protein PilW
HV559_RS04500	ENOG4105BZM	domain protein
HV559_RS04505	ENOG4105E1F	short-chain dehydrogenase reductase
HV559_RS04510	ENOG41069NU	Nitroreductase
HV559_RS04515	ENOG4105D07	Signal peptide peptidase, SppA
HV559_RS04520	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
HV559_RS04530	ENOG4105CSH	Transporter
HV559_RS04535	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
HV559_RS04540	ENOG4105P3Y	Acetolactate synthase 2 regulatory subunit
HV559_RS04550	ENOG4105EAU	Plays a role in nitrite reduction (By similarity)
HV559_RS04555	ENOG4105JJ8	Cytochrome c nitrite reductase, pentaheme subunit
HV559_RS04560	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
HV559_RS04565	ENOG4105DVI	reductase, NrfD
HV559_RS04570	ENOG4105DA4	cytochrome c-type biogenesis protein
HV559_RS04575	ENOG4107QX9	Thiol disulfide interChange protein
HV559_RS04580	ENOG4108DMF	Cytochrome C biogenesis protein
HV559_RS04585	ENOG4108M1T	Cytochrome c-type biogenesis protein
HV559_RS04600	ENOG4105W1Y	Transcriptional regulator
HV559_RS04615	ENOG4105CHH	sulfate transporter
HV559_RS04625	ENOG4105C0H	protease
HV559_RS04630	ENOG4105DHJ	ABC, transporter
HV559_RS04635	ENOG4105CY3	ABC transporter, permease
HV559_RS04640	ENOG4107PE3	Mammalian cell entry related domain protein
HV559_RS04645	ENOG4105E3I	toluene tolerance
HV559_RS04655	ENOG4105VFK	BolA family
HV559_RS04660	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
HV559_RS04665	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
HV559_RS04675	ENOG4105CDY	transcriptional regulatory protein
HV559_RS04680	ENOG4108TIT	dATP pyrophosphohydrolase
HV559_RS04700	ENOG4105DWU	Membrane
HV559_RS04705	ENOG4105D0M	Protease HtpX homolog
HV559_RS04710	ENOG4105W39	Membrane
HV559_RS04715	ENOG4105TMB	Formate nitrite transporter
HV559_RS04720	ENOG4105C6N	Formate acetyltransferase
HV559_RS04755	ENOG4105F1A	Pyruvate formate-lyase
HV559_RS04760	ENOG4105DGW	oligopeptidase A
HV559_RS04765	ENOG4105DEF	Extracellular solute-binding protein, family 5
HV559_RS04770	ENOG4105CQC	Prephenate dehydratase
HV559_RS04775	ENOG4107T0K	Adenylate cyclase
HV559_RS04780	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HV559_RS04785	ENOG4105K3M	)-transporter
HV559_RS04790	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
HV559_RS04800	ENOG4105EUR	Domain-Containing protein
HV559_RS04815	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
HV559_RS04820	ENOG4105EIB	trna rrna methyltransferase
HV559_RS04825	ENOG4105ECY	inositol monophosphatase
HV559_RS04830	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
HV559_RS04845	ENOG4105EYA	deoxyribonuclease
HV559_RS04850	ENOG4105HS1	biotin--protein ligase
HV559_RS04860	ENOG4108ISG	Major Facilitator
HV559_RS04875	ENOG4105M15	transport protein ExbD
HV559_RS04880	ENOG4105M8K	biopolymer transport protein
HV559_RS04890	ENOG4107QR8	Thioredoxin
HV559_RS04895	ENOG4105C3M	thioredoxin reductase
HV559_RS04910	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
HV559_RS04920	ENOG4105KAF	membrAne
HV559_RS04935	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
HV559_RS04940	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
HV559_RS04945	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
HV559_RS04955	ENOG4105DMQ	Methyltransferase
HV559_RS04970	ENOG4105DDQ	anthranilate synthase
HV559_RS04975	ENOG4105CRQ	synthase (Component I)
HV559_RS04980	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
HV559_RS04985	ENOG4105FE9	pseudouridine synthase
HV559_RS04995	ENOG4105D60	lipoprotein releasing system transmembrane protein
HV559_RS05000	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HV559_RS05005	ENOG4105D60	lipoprotein releasing system transmembrane protein
HV559_RS05020	ENOG41063JG	Transcriptional regulator
HV559_RS05025	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
HV559_RS05035	ENOG4105DDQ	anthranilate synthase
HV559_RS05040	ENOG4105CGY	Dna recombination protein
HV559_RS05045	ENOG4105CRQ	synthase (Component I)
HV559_RS05055	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
HV559_RS05060	ENOG4105Y3E	Modulates RecA activity (By similarity)
HV559_RS05065	ENOG41060QA	UPF0267 protein
HV559_RS05070	ENOG4108WI1	Dna topoisomerase
HV559_RS05080	ENOG4105E2X	shikimate dehydrogenase
HV559_RS05105	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
HV559_RS05120	ENOG4108HPI	phosphatidate Cytidylyltransferase
HV559_RS05135	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
HV559_RS05140	ENOG4108ZAI	phosphatidylglycerophosphatase a
HV559_RS05145	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
HV559_RS05150	ENOG4107YIM	Involved in the transcription termination process (By similarity)
HV559_RS05155	ENOG4105E4G	Type IV pilus
HV559_RS05180	ENOG4108JQC	penicillin-binding protein 1A
HV559_RS05185	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
HV559_RS05190	ENOG4105D49	3-dehydroquinate synthase
HV559_RS05195	ENOG4105DFE	Dna adenine methylase
HV559_RS05200	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
HV559_RS05205	ENOG4105DZ2	Transcriptional regulator
HV559_RS05210	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
HV559_RS05215	ENOG4105CAK	Cell division ATP-binding protein ftsE
HV559_RS05220	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HV559_RS05225	ENOG4106H78	methyltransferase
HV559_RS05230	ENOG4105XW2	UPF0263 protein
HV559_RS05235	ENOG4107UWN	reductase
HV559_RS05245	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
HV559_RS05255	ENOG4105BZA	Phosphoglycerate kinase
HV559_RS05260	ENOG4105D2N	Aldolase
HV559_RS05270	ENOG4105D38	putrescine abc transporter
HV559_RS05275	ENOG4105F38	ABC transporter, permease
HV559_RS05280	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HV559_RS05285	ENOG4105C4R	Atp-dependent dna helicase
HV559_RS05290	ENOG4108TVJ	Nitroreductase
HV559_RS05295	ENOG4105DC8	reductase
HV559_RS05305	ENOG4105F46	Necessary for formate dehydrogenase activity (By similarity)
HV559_RS05310	ENOG4108MG3	formate dehydrogenase
HV559_RS05315	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
HV559_RS05325	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
HV559_RS05335	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
HV559_RS05340	ENOG4105C8N	cysteinyl-tRNA synthetase
HV559_RS05345	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
HV559_RS05350	ENOG4108UMI	ABC transporter, permease
HV559_RS05355	ENOG4105D01	(LipO)protein
HV559_RS05360	ENOG4105D01	(LipO)protein
HV559_RS05370	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
HV559_RS05380	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
HV559_RS05385	ENOG4108IUZ	ABC transporter
HV559_RS05390	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
HV559_RS05395	ENOG4108P1K	Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity)
HV559_RS05400	ENOG4105CGK	Exodeoxyribonuclease III
HV559_RS05405	ENOG4105D3Y	Na H antiporter
HV559_RS05410	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
HV559_RS05415	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
HV559_RS05420	ENOG41061ZR	Transcriptional regulator
HV559_RS05425	ENOG4105EG2	ABC transporter, permease
HV559_RS05430	ENOG4105D56	permease protein
HV559_RS05435	ENOG4107FKK	extracellular solute-binding protein family 1
HV559_RS05440	ENOG4108IJ9	(ABC) transporter
HV559_RS05445	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
HV559_RS05450	ENOG4107W52	maltose operon periplasmic protein
HV559_RS05460	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
HV559_RS05470	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HV559_RS05505	ENOG4105C5H	ABC transporter
HV559_RS05510	ENOG4105CUZ	uba thif-type nad fad binding protein
HV559_RS05515	ENOG4105EWT	decarboxylase family
HV559_RS05520	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
HV559_RS05525	ENOG4108M8S	permease YjgP YjgQ family protein
HV559_RS05530	ENOG4108K5H	permease YjgP YjgQ family protein
HV559_RS05535	ENOG4105C0B	DNA polymerase III (alpha subunit)
HV559_RS05545	ENOG4105CFP	Peptidase U32
HV559_RS05550	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
HV559_RS05555	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
HV559_RS05560	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
HV559_RS05565	ENOG4105K8N	protein family UPF0079, ATPase
HV559_RS05570	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
HV559_RS05580	ENOG4105D5Q	Arginine ornithine antiporter
HV559_RS05590	ENOG4105D0S	secretion protein (HlyD
HV559_RS05595	ENOG4105CJ1	ABC, transporter
HV559_RS05600	ENOG4105CMI	transporter
HV559_RS05605	ENOG4105ETP	RND efflux system, outer membrane lipoprotein
HV559_RS05610	ENOG4105C0A	alcohol dehydrogenase
HV559_RS05615	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
HV559_RS05625	ENOG4105ECF	c-methyltransferase
HV559_RS05630	ENOG410601J	HemY protein
HV559_RS05635	ENOG4105CKW	Inner membrane protein yedI
HV559_RS05640	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
HV559_RS05645	ENOG4105EIN	peptidylprolyl cis-trans isomerase
HV559_RS05650	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
HV559_RS05655	ENOG4107TSG	Extracellular solute-binding protein, family 5
HV559_RS05660	ENOG4105D1F	ATP-binding protein
HV559_RS05670	ENOG4105EUJ	GTP cyclohydrolase i
HV559_RS05680	ENOG4105C59	p-type ATPase
HV559_RS05695	ENOG4108Z6Z	Transcriptional regulator
HV559_RS05710	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HV559_RS05715	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
HV559_RS05720	ENOG4107ZVW	dihydroneopterin aldolase
HV559_RS05725	ENOG4107T42	This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity)
HV559_RS05730	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HV559_RS05735	ENOG4105C01	Dihydroxy-acid dehydratase
HV559_RS05745	ENOG4108Z1B	Cyclase dehydrase
HV559_RS05750	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
HV559_RS05755	ENOG4105E0C	molybdate abc transporter
HV559_RS05760	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
HV559_RS05765	ENOG4105E3A	(ABC) transporter
HV559_RS05770	ENOG4105DA5	(ABC) transporter
HV559_RS05775	ENOG4107QMP	dna polymerase iii subunits gamma and tau
HV559_RS05780	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
HV559_RS05785	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
HV559_RS05790	ENOG4108MN8	Membrane
HV559_RS05795	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
HV559_RS05885	ENOG4105K63	Thioredoxin
HV559_RS05890	ENOG4105CEP	NADH dehydrogenase
HV559_RS05895	ENOG4105C7N	Xanthine uracil vitamin C permease
HV559_RS05900	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HV559_RS05905	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HV559_RS05910	ENOG4105VIE	preprotein translocase, subunit YajC
HV559_RS05915	ENOG4107RN3	metallophosphoesterase
HV559_RS05925	ENOG4105DQF	Hydrolase
HV559_RS05935	ENOG4105EMN	RNA polymerase sigma factor
HV559_RS05940	ENOG41069PW	sigma-e factor negative regulatory protein
HV559_RS05950	ENOG4105WMJ	Positive regulator of sigma E, RseC MucC
HV559_RS05955	ENOG4105CEY	Amp-dependent synthetase and ligase
HV559_RS05960	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
HV559_RS05965	ENOG4105CSA	Coproporphyrinogen iii oxidase
HV559_RS05970	ENOG4105KNR	Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity)
HV559_RS05985	ENOG4108JQ7	(ABC) transporter
HV559_RS05990	ENOG4108IYU	L-aspartate oxidase
HV559_RS05995	ENOG4105DFD	Na H antiporter
HV559_RS06005	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
HV559_RS06015	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
HV559_RS06020	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
HV559_RS06025	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
HV559_RS06030	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
HV559_RS06035	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
HV559_RS06040	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HV559_RS06045	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
HV559_RS06050	ENOG4105DIJ	Phosphoethanolamine transferase
HV559_RS06055	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
HV559_RS06060	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
HV559_RS06065	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HV559_RS06070	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
HV559_RS06075	ENOG4108DG9	Smr protein MutS2
HV559_RS06085	ENOG4108TZV	Membrane
HV559_RS06095	ENOG4105BZU	Histidine kinase
HV559_RS06100	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
HV559_RS06105	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
HV559_RS06110	ENOG4105C3J	Cysteine desulfurase
HV559_RS06115	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
HV559_RS06120	ENOG4108Z4V	iron-sulfur cluster assembly
HV559_RS06125	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
HV559_RS06130	ENOG4108RF1	Protein of unknown function DUF2625
HV559_RS06145	ENOG4108ZIT	Ferredoxin, 2FE-2S
HV559_RS06150	ENOG4105WVQ	Fe-S assembly protein IscX
HV559_RS06155	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HV559_RS06160	ENOG4105CSM	endonuclease III
HV559_RS06165	ENOG4105EJ9	Membrane
HV559_RS06170	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
HV559_RS06175	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
HV559_RS06180	ENOG4106CC8	Bacterial inner membrane protein
HV559_RS06185	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
HV559_RS06195	ENOG4107QHF	type ii secretion system protein e
HV559_RS06200	ENOG4105D7Q	type ii secretion system
HV559_RS06210	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
HV559_RS06215	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
HV559_RS06220	ENOG4105DJF	DNA polymerase III, delta' subunit
HV559_RS06230	ENOG4105C8T	Leucyl-tRNA synthetase
HV559_RS06275	ENOG4107XYH	virion morphogenesis protein
HV559_RS06385	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
HV559_RS06390	ENOG4105CM6	amino acid regulated cytosolic protein
HV559_RS06395	ENOG4105I7R	Adenylate cyclase
HV559_RS06405	ENOG4105DR9	pseudouridine synthase
HV559_RS06410	ENOG4105WP7	tRNA pseudouridine synthase C
HV559_RS06415	ENOG4105DK0	Indole-3-glycerol phosphate synthase
HV559_RS06420	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
HV559_RS06425	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HV559_RS06430	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
HV559_RS06435	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HV559_RS06445	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HV559_RS06450	ENOG4105DZP	Membrane-associated zinc metalloprotease
HV559_RS06455	ENOG4105KNE	Phosphatidate cytidylyltransferase
HV559_RS06460	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
HV559_RS06465	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
HV559_RS06470	ENOG4105C8U	phosphate abc transporter
HV559_RS06475	ENOG4105E2Z	phosphate ABC transporter (Permease
HV559_RS06485	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HV559_RS06490	ENOG4105BZU	Histidine kinase
HV559_RS06495	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
HV559_RS06520	ENOG4108IQE	Amp-dependent synthetase and ligase
HV559_RS06545	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
HV559_RS06550	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
HV559_RS06555	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
HV559_RS06560	ENOG4108Z6B	deaminase
HV559_RS06565	ENOG4105C1J	atp-dependent rna helicase
HV559_RS06570	ENOG4105RT1	May be involved in cell division (By similarity)
HV559_RS06575	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
HV559_RS06580	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HV559_RS06585	ENOG4105DB1	molybdopterin oxidoreductase
HV559_RS06600	ENOG4105MZG	transcriptional modulator of maze toxin, mazf
HV559_RS06605	ENOG4106A2Z	transcriptional regulator antitoxin, MazE
HV559_RS06610	ENOG4106WHD	Tetrathionate reductase
HV559_RS06615	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
HV559_RS06630	ENOG4108ZXC	Two component transcriptional regulator, luxr family
HV559_RS06640	ENOG4105CNN	ABC, transporter
HV559_RS06645	ENOG4105CNN	ABC, transporter
HV559_RS06650	ENOG4105C2J	ABC transporter
HV559_RS06675	ENOG4105DAH	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity)
HV559_RS06685	ENOG4108WZA	zeta toxin
HV559_RS06690	ENOG4105DUC	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity)
HV559_RS06695	ENOG4105E68	Sulfatase
HV559_RS06700	ENOG4105PAN	UPF0352 protein
HV559_RS06705	ENOG4105Y7M	Transcriptional regulator, TetR family
HV559_RS06710	ENOG410624X	efflux transporter, rnd family, mfp subunit
HV559_RS06715	ENOG4105BZS	acriflavin resistance protein
HV559_RS06720	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
HV559_RS06730	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
HV559_RS06740	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
HV559_RS06745	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
HV559_RS06755	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
HV559_RS06765	ENOG4105CJ3	phosphate transporter
HV559_RS06770	ENOG4107IX6	phosphate transport regulator
HV559_RS06775	ENOG4105CDU	Replicative dna helicase
HV559_RS06780	ENOG4105VNG	YcgL domain-containing protein
HV559_RS06785	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
HV559_RS06790	ENOG4105D1Q	UPF0246 protein
HV559_RS06800	ENOG41076HS	cation diffusion facilitator family transporter
HV559_RS06805	ENOG4105EXF	Zn-ribbon-containing, possibly nucleic-acid-binding protein
HV559_RS06810	ENOG4107R6U	sodium dicarboxylate symporter
HV559_RS06815	ENOG4108RCM	Nitroreductase
HV559_RS06820	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
HV559_RS06825	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
HV559_RS06830	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
HV559_RS06835	ENOG4108QBX	(LipO)protein
HV559_RS06840	ENOG4105C0H	protease
HV559_RS06845	ENOG4105CAT	Cytidine monophosphate kinase
HV559_RS06850	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
HV559_RS06855	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
HV559_RS06860	ENOG4105Q4A	inner membrane protein yciS
HV559_RS06865	ENOG4105CFV	Tetratricopeptide repeat protein
HV559_RS06870	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
HV559_RS06875	ENOG4108ZJT	translation initiation factor, Sui1
HV559_RS06880	ENOG4105CGH	5'-nucleotidase
HV559_RS06885	ENOG41080IJ	Diacylglycerol kinase
HV559_RS06890	ENOG4108IYC	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
HV559_RS06895	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
HV559_RS06905	ENOG41065CD	Exported protein
HV559_RS06910	ENOG4105D7X	high-affinity nickel-transporter
HV559_RS06915	ENOG4105BZG	amino acid carrier protein
HV559_RS06935	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
HV559_RS06940	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
HV559_RS06945	ENOG4105C7S	Dehydrogenase
HV559_RS06950	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
HV559_RS06955	ENOG4105FDK	ABC transporter
HV559_RS06960	ENOG4105DR5	peptidase
HV559_RS06965	ENOG4105T95	Thiol disulfide interChange protein
HV559_RS06970	ENOG4106IIQ	Outer membrane lipoprotein
HV559_RS06975	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
HV559_RS06985	ENOG4108K4B	hydrolase
HV559_RS06990	ENOG4105BZU	Histidine kinase
HV559_RS07000	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
HV559_RS07005	ENOG4105K8R	UPF0145 protein
HV559_RS07010	ENOG4108ZZ3	UPF0260 protein
HV559_RS07015	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
HV559_RS07020	ENOG4108JU8	Transcriptional regulator
HV559_RS07025	ENOG4108EVY	peptide transport periplasmic protein
HV559_RS07035	ENOG4108EU3	peptide transport system, permease
HV559_RS07040	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
HV559_RS07060	ENOG4107NA1	Endonuclease Exonuclease phosphatase
HV559_RS07065	ENOG4105E0X	reductase
HV559_RS07070	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
HV559_RS07080	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
HV559_RS07085	ENOG4105KME	endoribonuclease L-psp
HV559_RS07090	ENOG4106V8H	Nucleoid-associated protein
HV559_RS07095	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
HV559_RS07115	ENOG4105D82	Glutamate dehydrogenase
HV559_RS07120	ENOG4105CX6	glutaminyL-tRNA synthetase
HV559_RS07135	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
HV559_RS07145	ENOG4105VCN	Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system
HV559_RS07150	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
HV559_RS07155	ENOG4105E2R	ROK family
HV559_RS07160	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
HV559_RS07165	ENOG4105EW9	transcriptional regulator AsnC family
HV559_RS07170	ENOG4105CNU	cell division protein FtsK
HV559_RS07175	ENOG4105CGZ	zinc metallopeptidase
HV559_RS07180	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
HV559_RS07185	ENOG41072GX	Peptidase M22 Glycoprotease
HV559_RS07190	ENOG4107104	thymidine kinase
HV559_RS07200	ENOG4105CBT	Fructose-1,6-bisphosphatase
HV559_RS07205	ENOG4107A4G	HTH_XRE
HV559_RS07210	ENOG4107RAQ	aminopeptidase
HV559_RS07220	ENOG4108ZP8	Acetolactate synthase small subunit
HV559_RS07225	ENOG4105C7K	acetolactate synthase
HV559_RS07230	ENOG41077A9	carbonic anhydrase
HV559_RS07235	ENOG4108DNC	Involved in acetate metabolism (By similarity)
HV559_RS07245	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
HV559_RS07260	ENOG4105C28	cystathionine
HV559_RS07275	ENOG4105M08	Membrane
HV559_RS07280	ENOG4107QY8	reductase
HV559_RS07285	ENOG4107QIJ	Aconitate hydratase 2
HV559_RS07290	ENOG4108HMX	isocitrate dehydrogenase (NADP)
HV559_RS07295	ENOG4105BZN	citrate synthase
HV559_RS07300	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
HV559_RS07315	ENOG4108J3C	UTP-glucose-1-phosphate uridylyltransferase
HV559_RS07320	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
HV559_RS07335	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
HV559_RS07340	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
HV559_RS07350	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
HV559_RS07360	ENOG4108VD1	dedA family
HV559_RS07370	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
HV559_RS07375	ENOG4105EV9	Alpha Beta Hydrolase
HV559_RS07380	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
HV559_RS07385	ENOG4105CEY	Amp-dependent synthetase and ligase
HV559_RS07390	ENOG4105EGS	Mechanosensitive ion channel
HV559_RS07395	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
HV559_RS07400	ENOG4105HPZ	Involved in the removal of murein from the sacculus. May also facilitate integration of nascent murein strands into the sacculus by cleaving the peptide bonds between neighboring strands in mature murein (By similarity)
HV559_RS07405	ENOG4108IYH	Dna topoisomerase
HV559_RS07465	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
HV559_RS07480	ENOG4105CAR	Terminase, large subunit
HV559_RS07535	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
HV559_RS07540	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
HV559_RS07545	ENOG4105N42	UPF0307 protein
HV559_RS07555	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
HV559_RS07560	ENOG4108ZPB	UPF0306 protein
HV559_RS07570	ENOG4105NSG	hemerythrin hhe cation binding domain protein
HV559_RS07575	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
HV559_RS07585	ENOG4105VEQ	Cold shock protein
HV559_RS07590	ENOG4105QEK	Transcriptional regulator
HV559_RS07595	ENOG4108R66	Conserved Protein
HV559_RS07600	ENOG4105C9X	ppx gppa phosphatase
HV559_RS07605	ENOG41090HJ	UPF0265 protein
HV559_RS07610	ENOG4105CI1	PTS System
HV559_RS07615	ENOG4105CFH	Aspartokinase
HV559_RS07625	ENOG4108UJD	30S ribosomal protein S9
HV559_RS07630	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
HV559_RS07635	ENOG4108W2Q	Cytochrome d ubiquinol oxidase subunit III
HV559_RS07650	ENOG4107QY8	reductase
HV559_RS07655	ENOG4105CUW	cytochrome C-TYPE protein
HV559_RS07660	ENOG41061ZR	Transcriptional regulator
HV559_RS07670	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HV559_RS07675	ENOG4105M00	molybdopterin converting factor, subunit 1
HV559_RS07680	ENOG4108ZAF	Molybdopterin
HV559_RS07685	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
HV559_RS07700	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
HV559_RS07705	ENOG4105CGF	Aromatic amino acid aminotransferase
HV559_RS07710	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
HV559_RS07720	ENOG4105DXN	mazG family
HV559_RS07725	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
HV559_RS07730	ENOG4105E0F	Histidine kinase
HV559_RS07735	ENOG4107QNR	UPF0135 protein
HV559_RS07740	ENOG4108SXK	Transporter Drug Metabolite Exporter family
HV559_RS07745	ENOG4108RE7	deoxyribonuclease
HV559_RS07750	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
HV559_RS07760	ENOG4105DBE	peroxidase
HV559_RS07765	ENOG4105DB7	PHP domain protein
HV559_RS07775	ENOG4105CJB	Exodeoxyribonuclease I
HV559_RS07780	ENOG4105C5S	asparaginyl-tRNA synthetase
HV559_RS07785	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
HV559_RS07795	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
HV559_RS07800	ENOG4105KB2	stringent starvation protein b
HV559_RS07805	ENOG4107MKT	Stringent starvation protein a
HV559_RS07810	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
HV559_RS07815	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
HV559_RS07885	ENOG41063XI	Toxic component of a toxin-antitoxin (TA) module. A
HV559_RS07890	ENOG4105PF0	Antitoxin component of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin
HV559_RS07950	ENOG4108N0N	Phage Terminase Large Subunit
HV559_RS07955	ENOG41061CV	Terminase small subunit 
HV559_RS08010	ENOG4105RWQ	Protein of unknown function (DUF1364)
HV559_RS08015	ENOG41080ET	plasmid maintenance system killer protein
HV559_RS08020	ENOG4105VDM	plasmid maintenance system antidote protein, xre family
HV559_RS08025	ENOG4105WXW	Antirepressor
HV559_RS08040	ENOG4105CDU	Replicative dna helicase
HV559_RS08095	ENOG4105WXW	Antirepressor
HV559_RS08135	ENOG4105H40	
HV559_RS08200	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
HV559_RS08215	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
HV559_RS08225	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
HV559_RS08230	ENOG4105C2M	dna polymerase I
HV559_RS08245	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
HV559_RS08250	ENOG4105EMU	Dehydrogenase
HV559_RS08255	ENOG4107S6Z	Na H antiporter
HV559_RS08260	ENOG4108SAU	DNA-binding protein H-ns
HV559_RS08265	ENOG4105CIY	formyltetrahydrofolate deformylase
HV559_RS08270	ENOG4105DWV	Homoserine O-trans-acetylase
HV559_RS08275	ENOG4105CRK	lysyL-tRNA synthetase
HV559_RS08280	ENOG4105C03	ribonuclease
HV559_RS08295	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
HV559_RS08300	ENOG4105DDY	UPF0142 protein ycaO
HV559_RS08330	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
HV559_RS08350	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HV559_RS08355	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
HV559_RS08360	ENOG4105E98	transcriptional regulator DeoR family
HV559_RS08365	ENOG4107QTF	adenylosuccinate lyase
HV559_RS08370	ENOG41075W9	High frequency lysogenization protein HflD homolog
HV559_RS08375	ENOG4108JJ8	(ABC) transporter
HV559_RS08380	ENOG4108JJ9	ABC, transporter
HV559_RS08385	ENOG4105MA0	exported protein
HV559_RS08390	ENOG4105CFU	surface antigen
HV559_RS08400	ENOG41063SB	peptidase
HV559_RS08405	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
HV559_RS08410	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
HV559_RS08415	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
HV559_RS08420	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
HV559_RS08430	ENOG4107QKW	extracellular solute-binding protein family 1
HV559_RS08440	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HV559_RS08445	ENOG4107ZXU	DSBA oxidoreductase
HV559_RS08450	ENOG4105D7A	ATP-binding protein
HV559_RS08455	ENOG4105C1J	atp-dependent rna helicase
HV559_RS08460	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
HV559_RS08465	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
HV559_RS08475	ENOG4105C3F	Signal peptidase i
HV559_RS08480	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
HV559_RS08485	ENOG4105C5R	Aminotransferase
HV559_RS08515	ENOG4109045	doxx family
HV559_RS08525	ENOG4105E18	UPF0276 protein
HV559_RS08535	ENOG4108WQI	RNA Polymerase
HV559_RS08550	ENOG4107RNN	dihydropyrimidinase (EC 3.5.2.2)
HV559_RS08555	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
HV559_RS08565	ENOG4105DAA	L-lactate
HV559_RS08570	ENOG4105C5B	carbamate kinase
HV559_RS08575	ENOG4107REC	cytoplasmic protein
HV559_RS08580	ENOG4105DG4	malate L-lactate dehydrogenase
HV559_RS08585	ENOG4105S0E	allantoin catabolism protein
HV559_RS08595	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
HV559_RS08605	ENOG4105N16	Protein of unknown function (DUF2877)
HV559_RS08625	ENOG4105CA3	membrane-bound lytic murein transglycosylase
HV559_RS08630	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
HV559_RS08635	ENOG4105E96	Colicin v production protein
HV559_RS08640	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HV559_RS08650	ENOG4105FAA	peptidase M23
HV559_RS08660	ENOG4108XC3	NADH ubiquinone oxidoreductase
HV559_RS08665	ENOG4105M5K	heptosyltransferase
HV559_RS08670	ENOG4106WTF	Glycosyl transferase, family 2
HV559_RS08675	ENOG4105HBR	Rna-binding protein
HV559_RS08680	ENOG4105EYK	Phosphatidylglycerophosphatase B
HV559_RS08690	ENOG4105E0M	Sulfatase
HV559_RS08695	ENOG4105QVC	MOSC domain-containing protein
HV559_RS08705	ENOG4105CTB	Polyprenyl synthetase
HV559_RS08710	ENOG4105E7A	Glutamine amidotransferase
HV559_RS08715	ENOG4105FAV	ABC, transporter
HV559_RS08720	ENOG4105D1H	recombination factor protein RarA
HV559_RS08730	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
HV559_RS08735	ENOG4105DFF	Rod shape-determining protein mreb
HV559_RS08740	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
HV559_RS08745	ENOG4105DBI	uridine monophosphokinase
HV559_RS08750	ENOG4105DHP	deoxycytidine triphosphate deaminase
HV559_RS08755	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
HV559_RS08760	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
HV559_RS08765	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
HV559_RS08770	ENOG4108V0P	LemA family
HV559_RS08785	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
HV559_RS08790	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
HV559_RS08795	ENOG4105D4P	Coproporphyrinogen iii oxidase
HV559_RS08805	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
HV559_RS08815	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
HV559_RS08820	ENOG4105K9H	YciI-like protein
HV559_RS08825	ENOG4105NAU	thioesterase Superfamily protein
HV559_RS08830	ENOG4107835	probably involved in intracellular septation (By similarity)
HV559_RS08840	ENOG4105PQ6	UPF0208 membrane protein
HV559_RS08850	ENOG4105D06	uba thif-type nad fad binding protein
HV559_RS08855	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
HV559_RS08860	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
HV559_RS08865	ENOG4105C5H	ABC transporter
HV559_RS08875	ENOG4108W1A	pseudouridine synthase
HV559_RS08885	ENOG4106K28	UPF0283 membrane protein
HV559_RS08890	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
HV559_RS08895	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
HV559_RS08900	ENOG4105KCK	Peptidoglycan-associated lipoprotein
HV559_RS08905	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
HV559_RS08920	ENOG4105E02	MotA TolQ exbB proton channel
HV559_RS08925	ENOG4107YD3	Thioesterase
HV559_RS08940	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
HV559_RS08945	ENOG4105C4M	(Ubiquinol oxidase) subunit I
HV559_RS08970	ENOG4105M6F	mutator MutT protein
HV559_RS09000	ENOG4105M85	Bola protein
HV559_RS09010	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
HV559_RS09015	ENOG4108UJU	UPF0301 protein
HV559_RS09020	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
HV559_RS09025	ENOG4105DSF	transport protein
HV559_RS09030	ENOG4105BZG	amino acid carrier protein
HV559_RS09035	ENOG4105KK6	nuclease
HV559_RS09045	ENOG4108MBX	Secretion Protein
HV559_RS09065	ENOG4105C9B	Cysteine desulfurase
HV559_RS09070	ENOG4105CTQ	phosphohexokinase
HV559_RS09075	ENOG4108VTV	Inherit from NOG: Membrane
HV559_RS09085	ENOG4105C34	Pseudouridine synthase
HV559_RS09090	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HV559_RS09095	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HV559_RS09100	ENOG4105XQ6	frataxin-like protein
HV559_RS09105	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HV559_RS09110	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
HV559_RS09115	ENOG41082NX	50s ribosomal protein l35
HV559_RS09120	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
HV559_RS09135	ENOG4105E7U	AraC family transcriptional regulator
HV559_RS09140	ENOG4106HK8	GPR1 FUN34 yaaH family protein
HV559_RS09160	ENOG4105EE5	Membrane protein terC
HV559_RS09165	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
HV559_RS09175	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
HV559_RS09180	ENOG4108VBH	Uncharacterized protein conserved in bacteria (DUF2251)
HV559_RS09185	ENOG4105D0A	hydroxylase
HV559_RS09215	ENOG4105C09	Bile acid
HV559_RS09220	ENOG4105CUR	5'-nucleotidase, lipoprotein e(p4) family
HV559_RS09230	ENOG4108RRZ	Transcription elongation factor GreB
HV559_RS09235	ENOG4107QKA	exodeoxyribonuclease V beta
HV559_RS09245	ENOG4107QI1	Mate efflux family protein
HV559_RS09250	ENOG4107RUE	extracellular solute-binding protein family 1
HV559_RS09255	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HV559_RS09260	ENOG4108VMM	UPF0756 membrane protein
HV559_RS09265	ENOG4105CQ7	ATP-dependent helicase
HV559_RS09270	ENOG4108MJ5	VirK protein
HV559_RS09280	ENOG4107QX8	SPFH domain, Band 7 family protein
HV559_RS09285	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
HV559_RS09290	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
HV559_RS09300	ENOG4107TT5	NLP P60 protein
HV559_RS09305	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
HV559_RS09310	ENOG4107XHZ	cytoplasmic chaperone TorD family protein
HV559_RS09325	ENOG4108JU5	Magnesium and cobalt efflux protein
HV559_RS09330	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
HV559_RS09340	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
HV559_RS09345	ENOG4108R6K	riboflavin synthase, subunit alpha
HV559_RS09350	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
HV559_RS09355	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
HV559_RS09360	ENOG4105EMY	transcriptional regulator
HV559_RS09375	ENOG4105W1T	Glycosyl Transferase
HV559_RS09400	ENOG4105CV1	Transketolase (EC 2.2.1.1)
HV559_RS09405	ENOG4105C9A	Phoh family
HV559_RS09420	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
HV559_RS09425	ENOG4105C28	cystathionine
HV559_RS09430	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
HV559_RS09435	ENOG4105D6S	protein involved in catabolism of external DNA
HV559_RS09440	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
HV559_RS09445	ENOG4105D3G	Pseudouridine synthase
HV559_RS09465	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
HV559_RS09470	ENOG4105C2C	drug resistance transporter, Bcr CflA
HV559_RS09475	ENOG4105I08	Pseudouridine synthase
HV559_RS09480	ENOG4105DNI	Converts SHCHC to OSB (By similarity)
HV559_RS09490	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
HV559_RS09495	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
HV559_RS09505	ENOG4105DC1	bifunctional purine biosynthesis protein purh
HV559_RS09510	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HV559_RS09515	ENOG4105D1S	lipid A biosynthesis
HV559_RS09520	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
HV559_RS09525	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
HV559_RS09530	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
HV559_RS09555	ENOG4107QN2	dihydrolipoyl dehydrogenase
HV559_RS09560	ENOG4107QSN	dihydrolipoamide acetyltransferase
HV559_RS09565	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
HV559_RS09570	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
HV559_RS09575	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
HV559_RS09580	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
HV559_RS09590	ENOG4105BZ1	(ABC) transporter
HV559_RS09595	ENOG4105DVT	helicase
HV559_RS09600	ENOG4108JJB	ABC transporter
HV559_RS09610	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
HV559_RS09615	ENOG4108UUM	single-stranded DNA-binding protein
HV559_RS09620	ENOG4105C6Z	Gluconate
HV559_RS09625	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
HV559_RS09630	ENOG4105DIQ	Transcriptional regulator
HV559_RS09635	ENOG4105C37	(CBS) domain
HV559_RS09640	ENOG4105CVE	Lytic murein transglycosylase
HV559_RS09645	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
HV559_RS09650	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
HV559_RS09655	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
HV559_RS09660	ENOG4105CHV	Transcription elongation factor NusA
HV559_RS09665	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
HV559_RS09675	ENOG4107SC1	transglycosylase
HV559_RS09685	ENOG4105EPW	hflc protein
HV559_RS09690	ENOG4107QJR	hflk protein
HV559_RS09700	ENOG4105GPY	SprT protein
HV559_RS09705	ENOG41083KI	ribonuclease, T2
HV559_RS09745	ENOG4107QYX	exodeoxyribonuclease v alpha
HV559_RS09750	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
HV559_RS09755	ENOG4105E7U	AraC family transcriptional regulator
HV559_RS09760	ENOG4107KGK	dmso reductase anchor subunit
HV559_RS09765	ENOG4105QAX	Iron-sulfur
HV559_RS09770	ENOG4107QY8	reductase
HV559_RS09775	ENOG4108NEM	leader-binding protein dmsD
HV559_RS09805	ENOG4105CVR	type I restriction-modification system
HV559_RS09825	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HV559_RS09830	ENOG4105CFH	Aspartokinase
HV559_RS09835	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
HV559_RS09840	ENOG4105C6T	cysteine synthase
HV559_RS09845	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
HV559_RS09850	ENOG4105N1P	Ferredoxin-type protein
HV559_RS09855	ENOG4105C8Y	Acetylornithine aminotransferase
HV559_RS09870	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
HV559_RS09880	ENOG4105D9N	nucleoside
HV559_RS09885	ENOG4105E0X	reductase
HV559_RS09890	ENOG4108RYC	glycosyltransferase
HV559_RS09895	ENOG4108RJ9	Glycosyl transferase, family 2
HV559_RS09905	ENOG41068D6	Glycosyltransferase
HV559_RS09910	ENOG4105P7J	Transfers sialic acid from the substrate CMP-sialic acid donor to the terminal beta-D-galactosyl-1,4-acetyl-beta-D- glucosamine on the lacto-N-neotetraose branch of the lipooligosaccharide
HV559_RS09915	ENOG4108MY6	biosynthesis protein
HV559_RS09925	ENOG41080C8	DUF218 domain
HV559_RS09930	ENOG4105C25	Primosomal protein n'
HV559_RS09935	ENOG4105CHM	Aminotransferase
HV559_RS09940	ENOG4105E4F	Isochorismate synthase
HV559_RS09945	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
HV559_RS09950	ENOG4105W0Z	cytoplasmic protein
HV559_RS09955	ENOG4107QP8	phosphohexose isomerase
HV559_RS09960	ENOG4105DMR	ABC, transporter
HV559_RS09965	ENOG4105GBT	ABC transporter
HV559_RS09970	ENOG4106PMH	Extracellular solute-binding protein family 3
HV559_RS09975	ENOG4105E5Z	arginine transporter ATP-binding subunit
HV559_RS09980	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
HV559_RS09985	ENOG4108BPE	-transporting atpase
HV559_RS09990	ENOG4105CM2	brancheD-chain amino acid aminotransferase
HV559_RS09995	ENOG4105M2J	Glutaredoxin
HV559_RS10000	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
HV559_RS10005	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
HV559_RS10045	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
HV559_RS10050	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
HV559_RS10055	ENOG4105DKP	glycosyl transferase, family 9
HV559_RS10060	ENOG4105CA9	Pyruvate kinase
HV559_RS10065	ENOG4108BY2	phosphohistidine phosphatase
HV559_RS10070	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
HV559_RS10075	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
HV559_RS10080	ENOG4108MVK	Receptor
HV559_RS10090	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
HV559_RS10095	ENOG4108UYE	Lactoylglutathione lyase
HV559_RS10105	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HV559_RS10110	ENOG4105DJ0	Poly(A) Polymerase
HV559_RS10115	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HV559_RS10120	ENOG4105DP9	ABC transporter
HV559_RS10130	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
HV559_RS10135	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
HV559_RS10140	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
HV559_RS10155	ENOG4105CIN	aminoacyl-histidine dipeptidase
HV559_RS10160	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
HV559_RS10175	ENOG4105D6A	Electron transport complex
HV559_RS10180	ENOG4105EN6	Membrane
HV559_RS10185	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
HV559_RS10190	ENOG4108R3D	Electron transport complex
HV559_RS10195	ENOG4105DGN	Electron transport complex
HV559_RS10200	ENOG4105C5H	ABC transporter
HV559_RS10210	ENOG4107RZZ	dna polymerase iii epsilon subunit
HV559_RS10215	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
HV559_RS10225	ENOG4108VDV	Binds single-stranded DNA at the primosome assembly site (PAS) (By similarity)
HV559_RS10235	ENOG4105C12	Phosphoribosylglycinamide synthetase
HV559_RS10240	ENOG4106ZV1	Transferrin binding protein-like solute binding protein
HV559_RS10245	ENOG4107XDY	Nicotinamide Mononucleotide Transporter
HV559_RS10260	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
HV559_RS10265	ENOG4105CMR	udp-glucose 4-epimerase
HV559_RS10270	ENOG4105SYT	Methylenetetrahydrofolate reductase
HV559_RS10275	ENOG4105EYM	Major Facilitator superfamily
HV559_RS10285	ENOG4105RHG	
HV559_RS10290	ENOG4105C4R	Atp-dependent dna helicase
HV559_RS10295	ENOG4105ECP	epimerase
HV559_RS10300	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
HV559_RS10315	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
HV559_RS10325	ENOG4105C8Y	Acetylornithine aminotransferase
HV559_RS10335	ENOG4108IQ3	PTS system
HV559_RS10340	ENOG4105ETZ	PTS System
HV559_RS10345	ENOG4105F3R	pts system mannose fructose sorbose family iid
HV559_RS10375	ENOG4108VPT	UPF0234 protein
HV559_RS10380	ENOG4105EAC	phosphoserine phosphatase
HV559_RS10385	ENOG41062Z9	Membrane
HV559_RS10390	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
HV559_RS10395	ENOG4105CBX	hi0933 family
HV559_RS10400	ENOG4105C7N	Xanthine uracil vitamin C permease
HV559_RS10405	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
HV559_RS10410	ENOG4105NNH	LexA regulated protein
HV559_RS10415	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
HV559_RS10420	ENOG41090R7	Ferric uptake
HV559_RS10425	ENOG4105DY2	Paraquat-inducible protein b
HV559_RS10430	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
HV559_RS10435	ENOG4105BZ1	(ABC) transporter