locus-tag	class	description
MAQU_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MAQU_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MAQU_RS00040	COG1132	(ABC) transporter
MAQU_RS00045	COG5265	(ABC) transporter
MAQU_RS00050	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MAQU_RS00055	COG1074	ATP-dependent DNA helicase activity
MAQU_RS00060	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
MAQU_RS00090	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MAQU_RS00095	COG1129	ABC transporter
MAQU_RS00095	COG0842	Transport permease protein
MAQU_RS00100	COG0842	Transport permease protein
MAQU_RS00110	COG3040	lipid binding
MAQU_RS00170	COG4104	PAAR repeat-containing protein
MAQU_RS00180	COG2732	(Barnase) inhibitor
MAQU_RS00205	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MAQU_RS00210	COG0751	glycine-tRNA ligase activity
MAQU_RS00215	COG0752	glycyl-tRNA synthetase alpha subunit
MAQU_RS00220	COG0569	domain protein
MAQU_RS00230	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MAQU_RS00235	COG0242	peptide deformylase activity
MAQU_RS00245	COG0758	DNA mediated transformation
MAQU_RS00250	COG0009	L-threonylcarbamoyladenylate synthase
MAQU_RS00255	COG0408	coproporphyrinogen oxidase activity
MAQU_RS00260	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MAQU_RS00265	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
MAQU_RS00280	COG0071	Belongs to the small heat shock protein (HSP20) family
MAQU_RS00285	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MAQU_RS00300	COG2056	Na+-H+ antiporter family
MAQU_RS00310	COG2203	Gaf domain
MAQU_RS00310	COG3706	GGDEF domain
MAQU_RS00310	COG4251	negative regulation of phosphorylation
MAQU_RS00310	COG5001	Diguanylate cyclase
MAQU_RS00325	COG0534	Mate efflux family protein
MAQU_RS00330	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MAQU_RS00335	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MAQU_RS00340	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
MAQU_RS00370	COG0109	protoheme IX farnesyltransferase activity
MAQU_RS00375	COG1999	signal sequence binding
MAQU_RS00380	COG0477	Major facilitator Superfamily
MAQU_RS00385	COG1643	Atp-dependent helicase
MAQU_RS00390	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
MAQU_RS00400	COG0189	ligase activity
MAQU_RS00415	COG1917	Cupin 2, conserved barrel domain protein
MAQU_RS00420	COG1160	GTP binding
MAQU_RS00440	COG2204	response regulator
MAQU_RS00445	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
MAQU_RS00455	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
MAQU_RS00460	COG1028	Short-chain dehydrogenase reductase Sdr
MAQU_RS00465	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MAQU_RS00480	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MAQU_RS00505	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MAQU_RS00550	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MAQU_RS00555	COG0602	queuosine metabolic process
MAQU_RS00590	COG2814	Major facilitator Superfamily
MAQU_RS00595	COG2119	membrane
MAQU_RS00600	COG1376	ErfK ybiS ycfS ynhG family protein
MAQU_RS00600	COG1388	LysM domain
MAQU_RS00610	COG1030	water channel activity
MAQU_RS00615	COG0330	HflC and HflK could
MAQU_RS00655	COG2132	Multicopper oxidase
MAQU_RS00705	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MAQU_RS00710	COG0583	DNA-binding transcription factor activity
MAQU_RS00715	COG2259	Doxx family
MAQU_RS00720	COG3384	dioxygenase
MAQU_RS00725	COG1252	NADH dehydrogenase
MAQU_RS00730	COG1881	PFAM PEBP family protein
MAQU_RS00765	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MAQU_RS00770	COG0527	aspartate kinase activity
MAQU_RS00775	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MAQU_RS00790	COG2818	Glycosylase
MAQU_RS00795	COG2091	lysine biosynthetic process via aminoadipic acid
MAQU_RS00800	COG0259	pyridoxamine-phosphate oxidase activity
MAQU_RS00825	COG0121	glutamine amidotransferase
MAQU_RS00845	COG2197	response regulator
MAQU_RS00865	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MAQU_RS00875	COG0778	Nitroreductase
MAQU_RS00875	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
MAQU_RS00885	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MAQU_RS00885	COG2146	nitrite reductase [NAD(P)H] activity
MAQU_RS00890	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MAQU_RS00895	COG3707	response regulator
MAQU_RS00900	COG1116	anion transmembrane transporter activity
MAQU_RS00905	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MAQU_RS00910	COG1116	anion transmembrane transporter activity
MAQU_RS00910	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MAQU_RS00915	COG0243	molybdopterin cofactor binding
MAQU_RS00960	COG5002	protein histidine kinase activity
MAQU_RS00960	COG3447	MASE1 domain protein
MAQU_RS00960	COG5001	Diguanylate cyclase
MAQU_RS00985	COG1484	DNA-dependent DNA replication
MAQU_RS00990	COG4584	PFAM Integrase catalytic
MAQU_RS01010	COG1061	Type III restriction enzyme res subunit
MAQU_RS01090	COG2188	Transcriptional regulator
MAQU_RS01100	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MAQU_RS01125	COG3627	carbon phosphorus lyase activity
MAQU_RS01130	COG4107	phosphonate C-P lyase system protein PhnK
MAQU_RS01135	COG4778	phosphonate C-P lyase system protein PhnL
MAQU_RS01140	COG3454	Phosphonate metabolism
MAQU_RS01145	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
MAQU_RS01150	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
MAQU_RS01195	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
MAQU_RS01200	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
MAQU_RS01265	COG0784	Response regulator, receiver
MAQU_RS01270	COG2205	protein histidine kinase activity
MAQU_RS01285	COG2011	ABC-type metal ion transport system permease component
MAQU_RS01290	COG1464	Belongs to the NlpA lipoprotein family
MAQU_RS01295	COG0450	alkyl hydroperoxide reductase
MAQU_RS01300	COG1115	amino acid carrier protein
MAQU_RS01325	COG0534	Mate efflux family protein
MAQU_RS01335	COG0840	transmembrane signaling receptor activity
MAQU_RS01340	COG0733	neurotransmitter:sodium symporter activity
MAQU_RS01370	COG0406	alpha-ribazole phosphatase activity
MAQU_RS01375	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
MAQU_RS01390	COG4206	TonB-dependent receptor
MAQU_RS01395	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MAQU_RS01400	COG4139	cobalamin transport
MAQU_RS01405	COG1120	ATPase activity
MAQU_RS01410	COG1797	cobyrinic acid a,c-diamide synthase activity
MAQU_RS01420	COG1492	cobalamin metabolic process
MAQU_RS01430	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
MAQU_RS01435	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MAQU_RS01445	COG0463	Glycosyl transferase, family 2
MAQU_RS01450	COG0642	Histidine kinase
MAQU_RS01460	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MAQU_RS01465	COG0463	Glycosyl transferase, family 2
MAQU_RS01480	COG0318	PFAM AMP-dependent synthetase and ligase
MAQU_RS01485	COG4221	oxidoreductase activity
MAQU_RS01520	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
MAQU_RS01535	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MAQU_RS01570	COG1136	(ABC) transporter
MAQU_RS01585	COG0004	ammonium transporteR
MAQU_RS01595	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
MAQU_RS01600	COG3339	Conserved Protein
MAQU_RS01615	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
MAQU_RS01615	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MAQU_RS01625	COG0415	Belongs to the DNA photolyase family
MAQU_RS01665	COG2050	protein possibly involved in aromatic compounds catabolism
MAQU_RS01695	COG2962	Rard protein
MAQU_RS01700	COG0583	DNA-binding transcription factor activity
MAQU_RS01720	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
MAQU_RS01725	COG3842	ATPase activity
MAQU_RS01735	COG1177	transmembrane transport
MAQU_RS01750	COG3842	ATPase activity
MAQU_RS01760	COG1177	transmembrane transport
MAQU_RS01765	COG3706	GGDEF domain
MAQU_RS01770	COG1115	amino acid carrier protein
MAQU_RS01775	COG0589	response to stress
MAQU_RS01780	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
MAQU_RS01785	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
MAQU_RS01790	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MAQU_RS01800	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MAQU_RS01805	COG0737	Belongs to the 5'-nucleotidase family
MAQU_RS01820	COG0668	transmembrane transport
MAQU_RS01830	COG2186	Transcriptional regulator
MAQU_RS01835	COG1620	l-lactate permease
MAQU_RS01840	COG0247	lactate metabolic process
MAQU_RS01870	COG0579	oxidoreductase
MAQU_RS01910	COG1252	NADH dehydrogenase
MAQU_RS01925	COG0450	alkyl hydroperoxide reductase
MAQU_RS01950	COG1262	PFAM Formylglycine-generating sulfatase enzyme
MAQU_RS01955	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MAQU_RS01960	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
MAQU_RS01990	COG0582	viral genome integration into host DNA
MAQU_RS02000	COG4983	Phage plasmid primase, P4 family domain protein
MAQU_RS02020	COG2801	Transposase and inactivated derivatives
MAQU_RS02025	COG2963	transposase activity
MAQU_RS02030	COG3550	peptidyl-serine autophosphorylation
MAQU_RS02040	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
MAQU_RS02060	COG3335	DDE superfamily endonuclease
MAQU_RS02065	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
MAQU_RS02075	COG4584	PFAM Integrase catalytic
MAQU_RS02080	COG1484	DNA-dependent DNA replication
MAQU_RS02090	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
MAQU_RS02150	COG0667	Aldo Keto reductase
MAQU_RS02180	COG1309	transcriptional regulator
MAQU_RS02215	COG3239	Fatty acid desaturase
MAQU_RS02220	COG2909	trisaccharide binding
MAQU_RS02235	COG1917	Cupin 2, conserved barrel domain protein
MAQU_RS02250	COG4681	YaeQ
MAQU_RS02255	COG1380	Effector of murein hydrolase LrgA
MAQU_RS02270	COG0601	transmembrane transport
MAQU_RS02275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MAQU_RS02280	COG0444	Belongs to the ABC transporter superfamily
MAQU_RS02285	COG4608	Belongs to the ABC transporter superfamily
MAQU_RS02295	COG0006	proline dipeptidase activity
MAQU_RS02310	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MAQU_RS02325	COG3245	cytochrome
MAQU_RS02340	COG2183	response to ionizing radiation
MAQU_RS02345	COG2918	glutathione biosynthetic process
MAQU_RS02360	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
MAQU_RS02370	COG0545	Peptidyl-prolyl cis-trans isomerase
MAQU_RS02385	COG0488	(ABC) transporter
MAQU_RS02400	COG0746	molybdenum cofactor guanylyltransferase activity
MAQU_RS02405	COG0314	molybdopterin synthase activity
MAQU_RS02410	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
MAQU_RS02415	COG0303	'Molybdopterin
MAQU_RS02420	COG0521	Mo-molybdopterin cofactor biosynthetic process
MAQU_RS02430	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
MAQU_RS02445	COG2959	enzyme of heme biosynthesis
MAQU_RS02455	COG0181	hydroxymethylbilane synthase activity
MAQU_RS02465	COG3275	phosphorelay sensor kinase activity
MAQU_RS02470	COG0165	Argininosuccinate lyase
MAQU_RS02475	COG5002	protein histidine kinase activity
MAQU_RS02475	COG5001	Diguanylate cyclase
MAQU_RS02490	COG0019	diaminopimelate decarboxylase activity
MAQU_RS02495	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MAQU_RS02505	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
MAQU_RS02520	COG2205	protein histidine kinase activity
MAQU_RS02520	COG3437	response regulator, receiver
MAQU_RS02520	COG4999	Histidine kinase
MAQU_RS02520	COG3850	Histidine kinase
MAQU_RS02535	COG1752	Esterase of the alpha-beta hydrolase superfamily
MAQU_RS02555	COG0596	Alpha beta hydrolase
MAQU_RS02570	COG3321	synthase
MAQU_RS02570	COG0604	alcohol dehydrogenase
MAQU_RS02580	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
MAQU_RS02595	COG1960	acyl-CoA dehydrogenase activity
MAQU_RS02610	COG1595	DNA-templated transcription, initiation
MAQU_RS02620	COG1166	arginine decarboxylase activity
MAQU_RS02625	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
MAQU_RS02630	COG0004	ammonium transporteR
MAQU_RS02635	COG0347	Belongs to the P(II) protein family
MAQU_RS02650	COG0220	tRNA (guanine-N7-)-methyltransferase activity
MAQU_RS02660	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MAQU_RS02675	COG2813	Specifically methylates the guanine in position
MAQU_RS02675	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MAQU_RS02680	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MAQU_RS02685	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MAQU_RS02750	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MAQU_RS02760	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MAQU_RS02765	COG1561	YicC-like family, N-terminal region
MAQU_RS02815	COG0514	ATP-dependent DNA helicase (RecQ)
MAQU_RS02855	COG0420	3'-5' exonuclease activity
MAQU_RS02860	COG0419	ATPase involved in DNA repair
MAQU_RS02925	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MAQU_RS02930	COG1538	Outer membrane efflux protein
MAQU_RS02950	COG1309	transcriptional regulator
MAQU_RS02955	COG0667	Aldo Keto reductase
MAQU_RS02960	COG3713	MltA-interacting MipA family protein
MAQU_RS02990	COG1309	transcriptional regulator
MAQU_RS03000	COG1484	DNA-dependent DNA replication
MAQU_RS03005	COG4584	PFAM Integrase catalytic
MAQU_RS03010	COG0633	Ferredoxin
MAQU_RS03025	COG3335	DDE superfamily endonuclease
MAQU_RS03030	COG3039	Transposase
MAQU_RS03035	COG3039	Transposase
MAQU_RS03060	COG3335	DDE superfamily endonuclease
MAQU_RS03065	COG3239	Fatty acid desaturase
MAQU_RS03070	COG2909	trisaccharide binding
MAQU_RS03090	COG1917	Cupin 2, conserved barrel domain protein
MAQU_RS03095	COG2814	Major facilitator Superfamily
MAQU_RS03100	COG1566	PFAM secretion protein HlyD family protein
MAQU_RS03120	COG3077	Addiction module antitoxin, RelB DinJ family
MAQU_RS03140	COG0842	Transport permease protein
MAQU_RS03150	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MAQU_RS03155	COG0589	response to stress
MAQU_RS03160	COG4644	lycopene metabolic process
MAQU_RS03185	COG1758	RNA polymerase activity
MAQU_RS03190	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MAQU_RS03205	COG0583	DNA-binding transcription factor activity
MAQU_RS03210	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MAQU_RS03225	COG3383	formate dehydrogenase (NAD+) activity
MAQU_RS03295	COG0582	viral genome integration into host DNA
MAQU_RS03310	COG0358	DNA primase activity
MAQU_RS03315	COG0828	Belongs to the bacterial ribosomal protein bS21 family
MAQU_RS03320	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MAQU_RS03325	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
MAQU_RS03330	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MAQU_RS03340	COG0166	Belongs to the GPI family
MAQU_RS03345	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MAQU_RS03350	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
MAQU_RS03365	COG2204	response regulator
MAQU_RS03370	COG5002	protein histidine kinase activity
MAQU_RS03390	COG1489	DNA binding
MAQU_RS03410	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MAQU_RS03445	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
MAQU_RS03450	COG0352	thiamine-phosphate diphosphorylase activity
MAQU_RS03455	COG0351	phosphomethylpyrimidine kinase
MAQU_RS03460	COG1981	membrane
MAQU_RS03470	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MAQU_RS03485	COG0316	Belongs to the HesB IscA family
MAQU_RS03490	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
MAQU_RS03495	COG0739	heme binding
MAQU_RS03500	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MAQU_RS03550	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
MAQU_RS03550	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
MAQU_RS03555	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MAQU_RS03605	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MAQU_RS03610	COG0081	regulation of translation
MAQU_RS03615	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MAQU_RS03620	COG0222	ribosome binding
MAQU_RS03625	COG0085	RNA polymerase activity
MAQU_RS03630	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MAQU_RS03635	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MAQU_RS03640	COG0049	tRNA binding
MAQU_RS03645	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MAQU_RS03650	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MAQU_RS03655	COG0051	transcription antitermination factor activity, RNA binding
MAQU_RS03660	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MAQU_RS03665	COG0088	Forms part of the polypeptide exit tunnel
MAQU_RS03670	COG0089	rRNA binding
MAQU_RS03675	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MAQU_RS03680	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MAQU_RS03685	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MAQU_RS03690	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MAQU_RS03695	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MAQU_RS03700	COG0255	Belongs to the universal ribosomal protein uL29 family
MAQU_RS03705	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MAQU_RS03710	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MAQU_RS03715	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MAQU_RS03720	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MAQU_RS03725	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MAQU_RS03730	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MAQU_RS03735	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MAQU_RS03740	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MAQU_RS03745	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MAQU_RS03750	COG1841	ribosomal large subunit assembly
MAQU_RS03755	COG0200	Binds to the 23S rRNA
MAQU_RS03765	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MAQU_RS03770	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MAQU_RS03775	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MAQU_RS03780	COG0202	RNA polymerase activity
MAQU_RS03785	COG0203	ribosomal protein L17
MAQU_RS03795	COG2814	Major facilitator Superfamily
MAQU_RS03830	COG3267	Type II secretory pathway component ExeA
MAQU_RS03830	COG3409	Peptidoglycan-binding domain 1 protein
MAQU_RS03840	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MAQU_RS03860	COG2165	general secretion pathway protein
MAQU_RS03895	COG3852	Histidine kinase
MAQU_RS03910	COG1217	gtp-binding protein TYPA
MAQU_RS03920	COG1490	D-aminoacyl-tRNA deacylase activity
MAQU_RS03940	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
MAQU_RS03985	COG0859	PFAM glycosyl transferase family 9
MAQU_RS03990	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
MAQU_RS03990	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
MAQU_RS03995	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
MAQU_RS04000	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MAQU_RS04005	COG0859	PFAM glycosyl transferase family 9
MAQU_RS04020	COG0438	transferase activity, transferring glycosyl groups
MAQU_RS04025	COG1560	Kdo2-lipid A biosynthetic process
MAQU_RS04060	COG1560	Kdo2-lipid A biosynthetic process
MAQU_RS04065	COG1519	Transferase
MAQU_RS04070	COG1538	Outer membrane efflux protein
MAQU_RS04075	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MAQU_RS04080	COG0494	nUDIX hydrolase
MAQU_RS04085	COG3151	Protein conserved in bacteria
MAQU_RS04090	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
MAQU_RS04105	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MAQU_RS04110	COG0583	DNA-binding transcription factor activity
MAQU_RS04115	COG0509	glycine decarboxylation via glycine cleavage system
MAQU_RS04130	COG0494	nUDIX hydrolase
MAQU_RS04145	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MAQU_RS04150	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MAQU_RS04160	COG0018	arginyl-trna synthetase
MAQU_RS04170	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MAQU_RS04175	COG0254	rRNA binding
MAQU_RS04180	COG0281	malic enzyme
MAQU_RS04215	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MAQU_RS04230	COG0070	glutamate synthase
MAQU_RS04230	COG0069	glutamate synthase activity
MAQU_RS04230	COG0067	glutamate synthase
MAQU_RS04235	COG0493	'glutamate synthase
MAQU_RS04240	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MAQU_RS04260	COG0488	(ABC) transporter
MAQU_RS04265	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MAQU_RS04270	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MAQU_RS04275	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MAQU_RS04275	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MAQU_RS04285	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
MAQU_RS04290	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MAQU_RS04295	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
MAQU_RS04300	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
MAQU_RS04320	COG0583	DNA-binding transcription factor activity
MAQU_RS04325	COG0435	Glutathione S-transferase
MAQU_RS04330	COG0142	geranyltranstransferase activity
MAQU_RS04335	COG0261	This protein binds to 23S rRNA in the presence of protein L20
MAQU_RS04340	COG0211	Belongs to the bacterial ribosomal protein bL27 family
MAQU_RS04345	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MAQU_RS04350	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MAQU_RS04355	COG0268	Binds directly to 16S ribosomal RNA
MAQU_RS04360	COG0728	peptidoglycan biosynthetic process
MAQU_RS04365	COG0196	riboflavin kinase activity
MAQU_RS04370	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MAQU_RS04380	COG1047	Peptidyl-prolyl cis-trans
MAQU_RS04385	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MAQU_RS04440	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MAQU_RS04440	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
MAQU_RS04455	COG1496	oxidoreductase activity
MAQU_RS04470	COG0028	Belongs to the TPP enzyme family
MAQU_RS04475	COG0440	acetolactate synthase activity
MAQU_RS04480	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MAQU_RS04485	COG1183	phosphatidylcholine synthase activity
MAQU_RS04490	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MAQU_RS04495	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
MAQU_RS04540	COG1484	DNA-dependent DNA replication
MAQU_RS04545	COG4584	PFAM Integrase catalytic
MAQU_RS04555	COG0789	Transcriptional regulator
MAQU_RS04565	COG2205	protein histidine kinase activity
MAQU_RS04575	COG0784	Response regulator, receiver
MAQU_RS04575	COG2205	protein histidine kinase activity
MAQU_RS04585	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MAQU_RS04595	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MAQU_RS04600	COG2239	Acts as a magnesium transporter
MAQU_RS04605	COG2840	Smr protein MutS2
MAQU_RS04625	COG0235	Class ii aldolase
MAQU_RS04630	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
MAQU_RS04635	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
MAQU_RS04645	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MAQU_RS04660	COG1393	Belongs to the ArsC family
MAQU_RS04665	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MAQU_RS04675	COG0825	malonyl-CoA metabolic process
MAQU_RS04680	COG0037	tRNA processing
MAQU_RS04685	COG0504	CTP synthase activity
MAQU_RS04690	COG2877	3-deoxy-8-phosphooctulonate synthase activity
MAQU_RS04695	COG0148	phosphopyruvate hydratase activity
MAQU_RS04700	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
MAQU_RS04705	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
MAQU_RS04710	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
MAQU_RS04715	COG0585	pseudouridine synthase activity
MAQU_RS04720	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
MAQU_RS04725	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
MAQU_RS04750	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MAQU_RS04755	COG4660	Part of a membrane complex involved in electron transport
MAQU_RS04765	COG4658	electron transport chain
MAQU_RS04770	COG4656	Part of a membrane complex involved in electron transport
MAQU_RS04775	COG2878	Part of a membrane complex involved in electron transport
MAQU_RS04780	COG4657	Part of a membrane complex involved in electron transport
MAQU_RS04785	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MAQU_RS04785	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MAQU_RS04790	COG0489	protein tyrosine kinase activity
MAQU_RS04795	COG0717	Belongs to the dCTP deaminase family
MAQU_RS04800	COG3068	Protein conserved in bacteria
MAQU_RS04805	COG3977	Valine--pyruvate aminotransferase
MAQU_RS04815	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MAQU_RS04820	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
MAQU_RS04835	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MAQU_RS04840	COG1192	Involved in chromosome partitioning
MAQU_RS04845	COG3098	single-species biofilm formation
MAQU_RS04860	COG3023	N-Acetylmuramoyl-L-alanine amidase
MAQU_RS04870	COG0840	transmembrane signaling receptor activity
MAQU_RS04875	COG2096	Adenosyltransferase
MAQU_RS04885	COG0525	valine-tRNA ligase activity
MAQU_RS04890	COG2927	DNA polymerase III (CHI subunit)
MAQU_RS04895	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MAQU_RS04900	COG0795	lipopolysaccharide-transporting ATPase activity
MAQU_RS04905	COG0795	lipopolysaccharide-transporting ATPase activity
MAQU_RS04915	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MAQU_RS04925	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
MAQU_RS04945	COG3122	Protein conserved in bacteria
MAQU_RS04950	COG0513	Belongs to the DEAD box helicase family
MAQU_RS04955	COG3630	sodium ion export across plasma membrane
MAQU_RS04965	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
MAQU_RS04970	COG0587	DNA-directed DNA polymerase activity
MAQU_RS04980	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MAQU_RS04985	COG2154	pterin-4-alpha-carbinolamine dehydratase
MAQU_RS04995	COG4974	Belongs to the 'phage' integrase family
MAQU_RS05000	COG0517	IMP dehydrogenase activity
MAQU_RS05060	COG1484	DNA-dependent DNA replication
MAQU_RS05065	COG4584	PFAM Integrase catalytic
MAQU_RS05110	COG4584	PFAM Integrase catalytic
MAQU_RS05115	COG1484	DNA-dependent DNA replication
MAQU_RS05140	COG1942	4-Oxalocrotonate Tautomerase
MAQU_RS05165	COG0745	RESPONSE REGULATOR receiver
MAQU_RS05175	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MAQU_RS05175	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MAQU_RS05195	COG1136	(ABC) transporter
MAQU_RS05195	COG0577	efflux transmembrane transporter activity
MAQU_RS05200	COG0625	glutathione transferase activity
MAQU_RS05205	COG1067	ATP-dependent peptidase activity
MAQU_RS05215	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MAQU_RS05225	COG0405	Gamma-glutamyltransferase
MAQU_RS05230	COG0788	formyltetrahydrofolate deformylase activity
MAQU_RS05245	COG0077	Prephenate dehydratase
MAQU_RS05245	COG1605	Chorismate mutase
MAQU_RS05250	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MAQU_RS05255	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
MAQU_RS05260	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
MAQU_RS05270	COG0776	regulation of translation
MAQU_RS05280	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
MAQU_RS05285	COG0284	orotidine-5'-phosphate decarboxylase activity
MAQU_RS05295	COG0436	Aminotransferase
MAQU_RS05310	COG4770	biotin carboxylase activity
MAQU_RS05320	COG0167	dihydroorotate dehydrogenase activity
MAQU_RS05325	COG3130	regulation of translation
MAQU_RS05330	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
MAQU_RS05330	COG0116	Belongs to the methyltransferase superfamily
MAQU_RS05345	COG1362	aminopeptidase activity
MAQU_RS05365	COG4181	ATPase activity
MAQU_RS05370	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
MAQU_RS05410	COG0326	Molecular chaperone. Has ATPase activity
MAQU_RS05420	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
MAQU_RS05425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MAQU_RS05430	COG3588	fructose-bisphosphate aldolase
MAQU_RS05440	COG0454	-acetyltransferase
MAQU_RS05450	COG1794	racemase activity, acting on amino acids and derivatives
MAQU_RS05470	COG0583	DNA-binding transcription factor activity
MAQU_RS05475	COG0778	Nitroreductase
MAQU_RS05490	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MAQU_RS05520	COG1484	DNA-dependent DNA replication
MAQU_RS05525	COG1215	transferase activity, transferring glycosyl groups
MAQU_RS05545	COG1942	4-Oxalocrotonate Tautomerase
MAQU_RS05550	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MAQU_RS05580	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
MAQU_RS05585	COG4120	Belongs to the binding-protein-dependent transport system permease family
MAQU_RS05595	COG1022	Amp-dependent synthetase and ligase
MAQU_RS05605	COG1840	ABC-type Fe3 transport system, periplasmic component
MAQU_RS05620	COG3437	response regulator, receiver
MAQU_RS05630	COG1131	(ABC) transporter
MAQU_RS05635	COG0842	Transport permease protein
MAQU_RS05640	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MAQU_RS05640	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MAQU_RS05655	COG1815	bacterial-type flagellum-dependent cell motility
MAQU_RS05660	COG1558	bacterial-type flagellum-dependent cell motility
MAQU_RS05670	COG1749	Flagellar hook protein flgE
MAQU_RS05675	COG4787	bacterial-type flagellum-dependent cell motility
MAQU_RS05680	COG4786	Flagellar basal body rod
MAQU_RS05685	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
MAQU_RS05690	COG1706	bacterial-type flagellum-dependent cell motility
MAQU_RS05700	COG1256	bacterial-type flagellum assembly
MAQU_RS05715	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MAQU_RS05720	COG0343	queuine tRNA-ribosyltransferase activity
MAQU_RS05725	COG1862	Preprotein translocase
MAQU_RS05765	COG0105	UTP biosynthetic process
MAQU_RS05770	COG0820	rRNA (adenine-C2-)-methyltransferase activity
MAQU_RS05780	COG1426	Protein conserved in bacteria
MAQU_RS05785	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MAQU_RS05790	COG0124	histidyl-tRNA synthetase
MAQU_RS05795	COG2976	Protein conserved in bacteria
MAQU_RS05800	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MAQU_RS05805	COG1160	GTP binding
MAQU_RS05815	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MAQU_RS05830	COG1090	epimerase
MAQU_RS05855	COG0633	Ferredoxin
MAQU_RS05855	COG3217	Mosc domain protein beta barrel domain protein
MAQU_RS05860	COG0488	(ABC) transporter
MAQU_RS05870	COG0589	response to stress
MAQU_RS05880	COG1024	Enoyl-CoA hydratase
MAQU_RS05880	COG1250	3-hydroxyacyl-CoA dehydrogenase
MAQU_RS05885	COG0183	Belongs to the thiolase family
MAQU_RS05895	COG2084	Dehydrogenase
MAQU_RS05915	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
MAQU_RS05920	COG1053	succinate dehydrogenase
MAQU_RS05945	COG0045	succinate-CoA ligase (ADP-forming) activity
MAQU_RS05955	COG0180	Tryptophanyl-tRNA synthetase
MAQU_RS05965	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MAQU_RS05980	COG2186	Transcriptional regulator
MAQU_RS05990	COG3115	cell septum assembly
MAQU_RS05995	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MAQU_RS06010	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MAQU_RS06010	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
MAQU_RS06040	COG0784	Response regulator, receiver
MAQU_RS06040	COG0835	chemotaxis
MAQU_RS06045	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
MAQU_RS06080	COG1254	Belongs to the acylphosphatase family
MAQU_RS06085	COG3258	Cytochrome c
MAQU_RS06090	COG2863	cytochrome
MAQU_RS06105	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
MAQU_RS06145	COG1127	ABC transporter
MAQU_RS06150	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MAQU_RS06155	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
MAQU_RS06160	COG1178	ABC-type Fe3 transport system permease component
MAQU_RS06165	COG4143	(ABC) transporter
MAQU_RS06205	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MAQU_RS06255	COG3300	MHYT domain
MAQU_RS06255	COG5001	Diguanylate cyclase
MAQU_RS06275	COG4584	PFAM Integrase catalytic
MAQU_RS06280	COG1484	DNA-dependent DNA replication
MAQU_RS06295	COG4810	utilization protein
MAQU_RS06305	COG4766	ethanolamine catabolic process
MAQU_RS06310	COG4812	Cobalamin adenosyltransferase
MAQU_RS06315	COG0280	phosphate acetyltransferase
MAQU_RS06325	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
MAQU_RS06330	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
MAQU_RS06335	COG1012	belongs to the aldehyde dehydrogenase family
MAQU_RS06340	COG4820	ethanolamine utilization protein (EutJ)
MAQU_RS06345	COG1454	alcohol dehydrogenase
MAQU_RS06350	COG3192	ethanolamine utilization protein
MAQU_RS06375	COG4656	Part of a membrane complex involved in electron transport
MAQU_RS06410	COG1309	transcriptional regulator
MAQU_RS06425	COG1136	(ABC) transporter
MAQU_RS06440	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
MAQU_RS06510	COG0785	Cytochrome C biogenesis protein
MAQU_RS06585	COG4753	response regulator
MAQU_RS06585	COG2207	Transcriptional regulator
MAQU_RS06590	COG0642	Histidine kinase
MAQU_RS06600	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MAQU_RS06650	COG1484	DNA-dependent DNA replication
MAQU_RS06655	COG4584	PFAM Integrase catalytic
MAQU_RS06715	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
MAQU_RS06720	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MAQU_RS06730	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MAQU_RS06755	COG1201	RNA secondary structure unwinding
MAQU_RS06795	COG1484	DNA-dependent DNA replication
MAQU_RS06800	COG1484	DNA-dependent DNA replication
MAQU_RS06805	COG4584	PFAM Integrase catalytic
MAQU_RS06815	COG4584	PFAM Integrase catalytic
MAQU_RS06845	COG2226	methyltransferase
MAQU_RS06855	COG1278	Cold shock
MAQU_RS06860	COG0583	DNA-binding transcription factor activity
MAQU_RS06870	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MAQU_RS06875	COG0577	efflux transmembrane transporter activity
MAQU_RS06875	COG1136	(ABC) transporter
MAQU_RS06895	COG1070	Carbohydrate kinase
MAQU_RS06900	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MAQU_RS06905	COG0277	FAD linked oxidase domain protein
MAQU_RS06915	COG3031	protein transport across the cell outer membrane
MAQU_RS06975	COG5002	protein histidine kinase activity
MAQU_RS06975	COG0784	Response regulator, receiver
MAQU_RS07000	COG2186	Transcriptional regulator
MAQU_RS07010	COG0583	DNA-binding transcription factor activity
MAQU_RS07015	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MAQU_RS07020	COG3002	Belongs to the UPF0753 family
MAQU_RS07025	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
MAQU_RS07030	COG4208	sulfate ABC transporter
MAQU_RS07035	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
MAQU_RS07045	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MAQU_RS07050	COG1064	alcohol dehydrogenase
MAQU_RS07070	COG0515	serine threonine protein kinase
MAQU_RS07080	COG0022	dehydrogenase e1 component
MAQU_RS07090	COG0579	oxidoreductase
MAQU_RS07095	COG2020	methyltransferase activity
MAQU_RS07135	COG2010	Cytochrome c
MAQU_RS07160	COG0789	Transcriptional regulator
MAQU_RS07185	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MAQU_RS07190	COG0789	Transcriptional regulator
MAQU_RS07195	COG0815	Transfers the fatty acyl group on membrane lipoproteins
MAQU_RS07215	COG0789	Transcriptional regulator
MAQU_RS07230	COG0450	alkyl hydroperoxide reductase
MAQU_RS07245	COG3088	subunit of a heme lyase
MAQU_RS07260	COG0789	Transcriptional regulator
MAQU_RS07265	COG1309	transcriptional regulator
MAQU_RS07280	COG0583	DNA-binding transcription factor activity
MAQU_RS07285	COG1538	Outer membrane efflux protein
MAQU_RS07315	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MAQU_RS07320	COG0058	SHG alpha-glucan phosphorylase activity
MAQU_RS07345	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MAQU_RS07350	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MAQU_RS07355	COG0297	glycogen (starch) synthase activity
MAQU_RS07370	COG0514	ATP-dependent DNA helicase (RecQ)
MAQU_RS07390	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MAQU_RS07390	COG3153	acetyltransferase
MAQU_RS07400	COG0261	This protein binds to 23S rRNA in the presence of protein L20
MAQU_RS07400	COG3743	rRNA binding
MAQU_RS07410	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
MAQU_RS07415	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MAQU_RS07420	COG3639	organic phosphonate transmembrane transporter activity
MAQU_RS07440	COG1131	(ABC) transporter
MAQU_RS07445	COG0842	Transport permease protein
MAQU_RS07455	COG1024	Enoyl-CoA hydratase
MAQU_RS07495	COG2226	methyltransferase
MAQU_RS07500	COG1271	oxidase subunit
MAQU_RS07505	COG1294	oxidase, subunit
MAQU_RS07510	COG4988	ABC transporter
MAQU_RS07515	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MAQU_RS07520	COG3268	Saccharopine dehydrogenase
MAQU_RS07550	COG1047	Peptidyl-prolyl cis-trans
MAQU_RS07560	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MAQU_RS07570	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
MAQU_RS07580	COG2204	response regulator
MAQU_RS07590	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
MAQU_RS07605	COG4221	oxidoreductase activity
MAQU_RS07620	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MAQU_RS07635	COG0708	Exodeoxyribonuclease III
MAQU_RS07640	COG1309	transcriptional regulator
MAQU_RS07660	COG3453	Protein conserved in bacteria
MAQU_RS07660	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MAQU_RS07665	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
MAQU_RS07670	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
MAQU_RS07675	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
MAQU_RS07680	COG1984	allophanate hydrolase subunit 2
MAQU_RS07785	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
MAQU_RS07800	COG2920	part of a sulfur-relay system
MAQU_RS07815	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
MAQU_RS07815	COG0316	Belongs to the HesB IscA family
MAQU_RS07840	COG0616	signal peptide processing
MAQU_RS07855	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MAQU_RS07860	COG0328	RNA-DNA hybrid ribonuclease activity
MAQU_RS07870	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MAQU_RS07880	COG4166	transmembrane transport
MAQU_RS07885	COG4174	ABC transporter (Permease)
MAQU_RS07890	COG4239	(ABC) transporter, permease
MAQU_RS07895	COG4172	Belongs to the ABC transporter superfamily
MAQU_RS07915	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MAQU_RS07920	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MAQU_RS07920	COG1648	precorrin-2 dehydrogenase activity
MAQU_RS07925	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MAQU_RS07930	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
MAQU_RS07935	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
MAQU_RS07955	COG1286	toxin biosynthetic process
MAQU_RS07965	COG0285	dihydrofolate synthase activity
MAQU_RS07970	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MAQU_RS07975	COG0159	tryptophan synthase activity
MAQU_RS07985	COG0135	phosphoribosylanthranilate isomerase activity
MAQU_RS07990	COG0101	tRNA pseudouridine synthase activity
MAQU_RS08005	COG0473	3-isopropylmalate dehydrogenase activity
MAQU_RS08010	COG0066	3-isopropylmalate dehydratase activity
MAQU_RS08015	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MAQU_RS08030	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MAQU_RS08050	COG0596	Alpha beta hydrolase
MAQU_RS08105	COG0583	DNA-binding transcription factor activity
MAQU_RS08110	COG2909	trisaccharide binding
MAQU_RS08115	COG1199	ATP-dependent helicase activity
MAQU_RS08125	COG3409	Peptidoglycan-binding domain 1 protein
MAQU_RS08125	COG3267	Type II secretory pathway component ExeA
MAQU_RS08130	COG1752	Esterase of the alpha-beta hydrolase superfamily
MAQU_RS08135	COG2853	Lipoprotein
MAQU_RS08150	COG1643	Atp-dependent helicase
MAQU_RS08155	COG0318	PFAM AMP-dependent synthetase and ligase
MAQU_RS08160	COG2030	dehydratase
MAQU_RS08215	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MAQU_RS08230	COG2983	Belongs to the UPF0260 family
MAQU_RS08235	COG3100	YcgL domain-containing protein
MAQU_RS08245	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MAQU_RS08250	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MAQU_RS08255	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MAQU_RS08265	COG0676	glucose-6-phosphate 1-epimerase activity
MAQU_RS08270	COG0204	Acyl-transferase
MAQU_RS08280	COG4191	Histidine kinase
MAQU_RS08285	COG2204	response regulator
MAQU_RS08320	COG1216	Glycosyl transferase, family 2
MAQU_RS08320	COG0463	Glycosyl transferase, family 2
MAQU_RS08330	COG4584	PFAM Integrase catalytic
MAQU_RS08335	COG1484	DNA-dependent DNA replication
MAQU_RS08370	COG0367	asparagine synthase
MAQU_RS08380	COG0438	transferase activity, transferring glycosyl groups
MAQU_RS08395	COG0438	transferase activity, transferring glycosyl groups
MAQU_RS08400	COG1215	transferase activity, transferring glycosyl groups
MAQU_RS08415	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
MAQU_RS08440	COG0438	transferase activity, transferring glycosyl groups
MAQU_RS08445	COG2843	Capsule synthesis protein
MAQU_RS08480	COG0489	protein tyrosine kinase activity
MAQU_RS08495	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MAQU_RS08500	COG2079	MmgE PrpD family protein
MAQU_RS08515	COG0372	Belongs to the citrate synthase family
MAQU_RS08520	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MAQU_RS08530	COG2943	transferase activity, transferring hexosyl groups
MAQU_RS08540	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
MAQU_RS08560	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MAQU_RS08560	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MAQU_RS08570	COG0438	transferase activity, transferring glycosyl groups
MAQU_RS08590	COG2353	YceI-like domain
MAQU_RS08620	COG0564	pseudouridine synthase activity
MAQU_RS08635	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
MAQU_RS08645	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MAQU_RS08650	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MAQU_RS08660	COG0425	Belongs to the sulfur carrier protein TusA family
MAQU_RS08665	COG4783	chaperone-mediated protein folding
MAQU_RS08670	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MAQU_RS08685	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
MAQU_RS08690	COG2885	chlorophyll binding
MAQU_RS08695	COG0823	Involved in the tonB-independent uptake of proteins
MAQU_RS08715	COG0824	Thioesterase
MAQU_RS08720	COG2255	four-way junction helicase activity
MAQU_RS08725	COG0632	four-way junction helicase activity
MAQU_RS08730	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
MAQU_RS08735	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MAQU_RS08765	COG1063	alcohol dehydrogenase
MAQU_RS08785	COG3846	protein secretion by the type IV secretion system
MAQU_RS08805	COG4691	Plasmid stability protein
MAQU_RS08825	COG0582	viral genome integration into host DNA
MAQU_RS08830	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MAQU_RS08830	COG0519	Catalyzes the synthesis of GMP from XMP
MAQU_RS08840	COG1570	exodeoxyribonuclease VII activity
MAQU_RS08850	COG1278	Cold shock
MAQU_RS08855	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MAQU_RS08860	COG1522	sequence-specific DNA binding
MAQU_RS08865	COG1309	transcriptional regulator
MAQU_RS08870	COG0442	prolyl-tRNA aminoacylation
MAQU_RS08875	COG0812	UDP-N-acetylmuramate dehydrogenase activity
MAQU_RS08880	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MAQU_RS08885	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
MAQU_RS08890	COG2835	tetraacyldisaccharide 4'-kinase activity
MAQU_RS08895	COG1663	tetraacyldisaccharide 4'-kinase activity
MAQU_RS08900	COG1132	(ABC) transporter
MAQU_RS08905	COG0848	biopolymer transport protein
MAQU_RS08910	COG0811	peptide transport
MAQU_RS08915	COG0658	competence protein
MAQU_RS08915	COG2333	competence protein COMEC
MAQU_RS08925	COG1136	(ABC) transporter
MAQU_RS08945	COG2957	Belongs to the agmatine deiminase family
MAQU_RS08950	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MAQU_RS08955	COG0714	Associated with various cellular activities
MAQU_RS08960	COG0492	ferredoxin-NADP+ reductase activity
MAQU_RS08970	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
MAQU_RS08975	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MAQU_RS08985	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
MAQU_RS08990	COG1278	Cold shock
MAQU_RS09005	COG0482	sulfurtransferase activity
MAQU_RS09010	COG2915	High frequency lysogenization protein hflD homolog
MAQU_RS09020	COG2850	peptidyl-arginine hydroxylation
MAQU_RS09040	COG5002	protein histidine kinase activity
MAQU_RS09040	COG0784	Response regulator, receiver
MAQU_RS09040	COG2205	protein histidine kinase activity
MAQU_RS09045	COG1846	Transcriptional regulator
MAQU_RS09050	COG0386	Belongs to the glutathione peroxidase family
MAQU_RS09055	COG0436	Aminotransferase
MAQU_RS09065	COG0501	Belongs to the peptidase M48B family
MAQU_RS09070	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MAQU_RS09075	COG0513	Belongs to the DEAD box helicase family
MAQU_RS09080	COG3101	peptidyl-lysine hydroxylation
MAQU_RS09100	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
MAQU_RS09115	COG3278	Belongs to the heme-copper respiratory oxidase family
MAQU_RS09130	COG2010	Cytochrome c
MAQU_RS09135	COG0348	domain, Protein
MAQU_RS09145	COG2217	Heavy metal translocating P-type atpase
MAQU_RS09160	COG0037	tRNA processing
MAQU_RS09165	COG1309	transcriptional regulator
MAQU_RS09170	COG0484	heat shock protein binding
MAQU_RS09205	COG0471	metal ion transport
MAQU_RS09220	COG3243	poly(R)-hydroxyalkanoic acid synthase
MAQU_RS09285	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MAQU_RS09330	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MAQU_RS09335	COG1573	uracil-dna glycosylase
MAQU_RS09340	COG0837	glucose binding
MAQU_RS09355	COG0800	Aldolase
MAQU_RS09370	COG1737	Transcriptional regulator
MAQU_RS09375	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MAQU_RS09385	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MAQU_RS09390	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MAQU_RS09395	COG0740	serine-type endopeptidase activity
MAQU_RS09400	COG0544	peptidyl-prolyl cis-trans isomerase activity
MAQU_RS09425	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MAQU_RS09430	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
MAQU_RS09435	COG0215	cysteine-tRNA ligase activity
MAQU_RS09440	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MAQU_RS09445	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MAQU_RS09450	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MAQU_RS09455	COG4572	Cation transport regulator
MAQU_RS09460	COG5285	phytanoyl-CoA dioxygenase
MAQU_RS09470	COG5002	protein histidine kinase activity
MAQU_RS09470	COG0784	Response regulator, receiver
MAQU_RS09475	COG4584	PFAM Integrase catalytic
MAQU_RS09480	COG1484	DNA-dependent DNA replication
MAQU_RS09485	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MAQU_RS09500	COG0583	DNA-binding transcription factor activity
MAQU_RS09515	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MAQU_RS09525	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MAQU_RS09530	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MAQU_RS09535	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MAQU_RS09540	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MAQU_RS09545	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MAQU_RS09555	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
MAQU_RS09560	COG0416	fatty acid biosynthetic process
MAQU_RS09565	COG0333	Belongs to the bacterial ribosomal protein bL32 family
MAQU_RS09590	COG0564	pseudouridine synthase activity
MAQU_RS09595	COG1530	ribonuclease E activity
MAQU_RS09605	COG0613	PHP domain protein
MAQU_RS09610	COG2350	Protein conserved in bacteria
MAQU_RS09625	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MAQU_RS09635	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
MAQU_RS09680	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MAQU_RS09685	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
MAQU_RS09695	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MAQU_RS09705	COG0709	Synthesizes selenophosphate from selenide and ATP
MAQU_RS09720	COG0438	transferase activity, transferring glycosyl groups
MAQU_RS09750	COG1028	Short-chain dehydrogenase reductase Sdr
MAQU_RS09755	COG1803	Methylglyoxal synthase
MAQU_RS09770	COG2226	methyltransferase
MAQU_RS09775	COG1061	Type III restriction enzyme res subunit
MAQU_RS09780	COG1940	carbohydrate kinase activity
MAQU_RS09790	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
MAQU_RS09815	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MAQU_RS09820	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MAQU_RS09830	COG1605	Chorismate mutase
MAQU_RS09830	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
MAQU_RS09840	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MAQU_RS09850	COG1477	protein flavinylation
MAQU_RS09855	COG2871	sodium ion transport
MAQU_RS09860	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
MAQU_RS09875	COG1805	sodium ion transport
MAQU_RS09880	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
MAQU_RS09890	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MAQU_RS09905	COG0668	transmembrane transport
MAQU_RS09925	COG0307	riboflavin synthase, alpha
MAQU_RS09930	COG2813	Specifically methylates the guanine in position
MAQU_RS09935	COG2813	Specifically methylates the guanine in position
MAQU_RS09940	COG0288	reversible hydration of carbon dioxide
MAQU_RS09950	COG0714	Associated with various cellular activities
MAQU_RS09970	COG2304	oxidoreductase activity
MAQU_RS09995	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MAQU_RS10005	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
MAQU_RS10020	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MAQU_RS10025	COG4133	protoheme IX ABC transporter activity
MAQU_RS10040	COG0714	Associated with various cellular activities
MAQU_RS10055	COG0835	chemotaxis
MAQU_RS10065	COG1192	Involved in chromosome partitioning
MAQU_RS10075	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
MAQU_RS10080	COG2201	protein-glutamate methylesterase activity
MAQU_RS10085	COG2198	Histidine kinase
MAQU_RS10085	COG0643	Histidine kinase
MAQU_RS10085	COG0784	Response regulator, receiver
MAQU_RS10090	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
MAQU_RS10115	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MAQU_RS10120	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MAQU_RS10215	COG1677	Flagellar hook-basal body complex protein FliE
MAQU_RS10260	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MAQU_RS10270	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
MAQU_RS10280	COG2911	Protein conserved in bacteria
MAQU_RS10285	COG0729	surface antigen
MAQU_RS10300	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
MAQU_RS10310	COG0183	Belongs to the thiolase family
MAQU_RS10350	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MAQU_RS10370	COG1704	LemA family
MAQU_RS10375	COG0501	Belongs to the peptidase M48B family
MAQU_RS10395	COG0459	protein refolding
MAQU_RS10400	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MAQU_RS10410	COG1028	Short-chain dehydrogenase reductase Sdr
MAQU_RS10425	COG2267	carboxylic ester hydrolase activity
MAQU_RS10430	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MAQU_RS10445	COG1322	Protein conserved in bacteria
MAQU_RS10455	COG0189	ligase activity
MAQU_RS10455	COG4067	protein conserved in archaea
MAQU_RS10465	COG0189	ligase activity
MAQU_RS10470	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MAQU_RS10475	COG0069	glutamate synthase activity
MAQU_RS10485	COG2271	Major facilitator Superfamily
MAQU_RS10500	COG1522	sequence-specific DNA binding
MAQU_RS10505	COG1929	Belongs to the glycerate kinase type-1 family
MAQU_RS10525	COG0776	regulation of translation
MAQU_RS10530	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MAQU_RS10530	COG0072	phenylalanine-tRNA ligase activity
MAQU_RS10535	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MAQU_RS10540	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MAQU_RS10545	COG0291	Belongs to the bacterial ribosomal protein bL35 family
MAQU_RS10550	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MAQU_RS10555	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MAQU_RS10565	COG2358	TRAP transporter, solute receptor (TAXI family
MAQU_RS10570	COG2409	Drug exporters of the RND superfamily
MAQU_RS10585	COG0308	aminopeptidase N
MAQU_RS10595	COG3139	Protein of unknown function (DUF1315)
MAQU_RS10600	COG0705	Rhomboid family
MAQU_RS10605	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
MAQU_RS10610	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MAQU_RS10620	COG1902	pentaerythritol trinitrate reductase activity
MAQU_RS10620	COG0446	pyridine nucleotide-disulphide oxidoreductase
MAQU_RS10650	COG4566	intracellular signal transduction
MAQU_RS10655	COG1067	ATP-dependent peptidase activity
MAQU_RS10670	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MAQU_RS10675	COG1546	Belongs to the CinA family
MAQU_RS10680	COG1252	NADH dehydrogenase
MAQU_RS10695	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MAQU_RS10700	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
MAQU_RS10710	COG1307	EDD domain protein, DegV family
MAQU_RS10725	COG0318	PFAM AMP-dependent synthetase and ligase
MAQU_RS10730	COG4191	Histidine kinase
MAQU_RS10735	COG4566	intracellular signal transduction
MAQU_RS10740	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MAQU_RS10760	COG2081	HI0933 family
MAQU_RS10765	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MAQU_RS10770	COG0589	response to stress
MAQU_RS10775	COG0659	secondary active sulfate transmembrane transporter activity
MAQU_RS10785	COG3145	DNA-N1-methyladenine dioxygenase activity
MAQU_RS10790	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
MAQU_RS10805	COG0154	amidase activity
MAQU_RS10810	COG2203	Gaf domain
MAQU_RS10810	COG3706	GGDEF domain
MAQU_RS10810	COG4251	negative regulation of phosphorylation
MAQU_RS10810	COG5001	Diguanylate cyclase
MAQU_RS10815	COG0564	pseudouridine synthase activity
MAQU_RS10845	COG0129	dihydroxy-acid dehydratase activity
MAQU_RS10850	COG0183	Belongs to the thiolase family
MAQU_RS10855	COG1960	acyl-CoA dehydrogenase activity
MAQU_RS10870	COG1960	acyl-CoA dehydrogenase activity
MAQU_RS10875	COG3547	Transposase (IS116 IS110 IS902 family)
MAQU_RS10880	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MAQU_RS10890	COG4770	biotin carboxylase activity
MAQU_RS10920	COG1024	Enoyl-CoA hydratase
MAQU_RS10925	COG1960	acyl-CoA dehydrogenase activity
MAQU_RS10945	COG3842	ATPase activity
MAQU_RS10950	COG1176	ABC-type spermidine putrescine transport system, permease component I
MAQU_RS10955	COG1177	transmembrane transport
MAQU_RS10965	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MAQU_RS10970	COG3938	Belongs to the proline racemase family
MAQU_RS10980	COG0628	permease
MAQU_RS11035	COG0217	transcriptional regulatory protein
MAQU_RS11040	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MAQU_RS11040	COG0519	Catalyzes the synthesis of GMP from XMP
MAQU_RS11075	COG0523	cobalamin synthesis protein
MAQU_RS11080	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
MAQU_RS11110	COG1234	tRNA 3'-trailer cleavage
MAQU_RS11125	COG3228	Belongs to the MtfA family
MAQU_RS11135	COG1944	ATP diphosphatase activity
MAQU_RS11140	COG5507	3-demethylubiquinone-9 3-methyltransferase
MAQU_RS11145	COG3795	YCII-related domain
MAQU_RS11150	COG4941	Belongs to the sigma-70 factor family
MAQU_RS11165	COG2226	methyltransferase
MAQU_RS11185	COG2824	Alkylphosphonate utilization operon protein PhnA
MAQU_RS11195	COG1671	Belongs to the UPF0178 family
MAQU_RS11200	COG1132	(ABC) transporter
MAQU_RS11205	COG1120	ATPase activity
MAQU_RS11210	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
MAQU_RS11230	COG2133	pyrroloquinoline quinone binding
MAQU_RS11250	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
MAQU_RS11265	COG1028	Short-chain dehydrogenase reductase Sdr
MAQU_RS11285	COG3547	Transposase (IS116 IS110 IS902 family)
MAQU_RS11290	COG1960	acyl-CoA dehydrogenase activity
MAQU_RS11310	COG0473	3-isopropylmalate dehydrogenase activity
MAQU_RS11315	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MAQU_RS11330	COG0436	Aminotransferase
MAQU_RS11360	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MAQU_RS11375	COG3852	Histidine kinase
MAQU_RS11395	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
MAQU_RS11400	COG2816	NAD+ diphosphatase activity
MAQU_RS11405	COG2937	Belongs to the GPAT DAPAT family
MAQU_RS11410	COG0742	ribosomal rna small subunit methyltransferase
MAQU_RS11420	COG1214	PFAM Peptidase M22, glycoprotease
MAQU_RS11425	COG0563	adenylate kinase activity
MAQU_RS11435	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MAQU_RS11450	COG3956	TIGRFAM MazG family protein
MAQU_RS11455	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MAQU_RS11460	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MAQU_RS11470	COG2205	protein histidine kinase activity
MAQU_RS11470	COG5002	protein histidine kinase activity
MAQU_RS11470	COG0784	Response regulator, receiver
MAQU_RS11480	COG1381	Involved in DNA repair and RecF pathway recombination
MAQU_RS11485	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MAQU_RS11490	COG0571	ribonuclease III activity
MAQU_RS11500	COG0681	Belongs to the peptidase S26 family
MAQU_RS11505	COG0481	GTPase activity
MAQU_RS11515	COG0583	DNA-binding transcription factor activity
MAQU_RS11550	COG1484	DNA-dependent DNA replication
MAQU_RS11555	COG4584	PFAM Integrase catalytic
MAQU_RS11570	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MAQU_RS11575	COG3086	response to oxidative stress
MAQU_RS11620	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MAQU_RS11625	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
MAQU_RS11630	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MAQU_RS11635	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
MAQU_RS11650	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MAQU_RS11660	COG0335	large ribosomal subunit rRNA binding
MAQU_RS11665	COG0336	Belongs to the RNA methyltransferase TrmD family
MAQU_RS11670	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MAQU_RS11675	COG0228	four-way junction DNA binding
MAQU_RS11690	COG1061	Type III restriction enzyme res subunit
MAQU_RS11705	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MAQU_RS11710	COG3639	organic phosphonate transmembrane transporter activity
MAQU_RS11715	COG3454	Phosphonate metabolism
MAQU_RS11735	COG3627	carbon phosphorus lyase activity
MAQU_RS11740	COG4107	phosphonate C-P lyase system protein PhnK
MAQU_RS11745	COG4778	phosphonate C-P lyase system protein PhnL
MAQU_RS11755	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
MAQU_RS11790	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MAQU_RS11820	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MAQU_RS11830	COG4536	flavin adenine dinucleotide binding
MAQU_RS11845	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
MAQU_RS11850	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MAQU_RS11855	COG3842	ATPase activity
MAQU_RS11860	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MAQU_RS11865	COG2205	protein histidine kinase activity
MAQU_RS11870	COG0745	RESPONSE REGULATOR receiver
MAQU_RS11885	COG1047	Peptidyl-prolyl cis-trans
MAQU_RS11890	COG0427	acetyl-CoA hydrolase
MAQU_RS11900	COG0667	Aldo Keto reductase
MAQU_RS11910	COG0671	phosphoesterase, PA-phosphatase related
MAQU_RS11925	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MAQU_RS11940	COG0850	regulation of cytokinetic process
MAQU_RS11945	COG2894	cell division
MAQU_RS11950	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
MAQU_RS11965	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
MAQU_RS11970	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
MAQU_RS11985	COG1304	FMN binding
MAQU_RS11990	COG0028	Belongs to the TPP enzyme family
MAQU_RS12005	COG4191	Histidine kinase
MAQU_RS12030	COG0189	ligase activity
MAQU_RS12035	COG0189	ligase activity
MAQU_RS12035	COG4067	protein conserved in archaea
MAQU_RS12040	COG0668	transmembrane transport
MAQU_RS12065	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MAQU_RS12070	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MAQU_RS12080	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
MAQU_RS12085	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MAQU_RS12095	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MAQU_RS12100	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MAQU_RS12105	COG0193	aminoacyl-tRNA hydrolase activity
MAQU_RS12110	COG0012	GTP binding
MAQU_RS12135	COG2873	o-acetylhomoserine
MAQU_RS12140	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MAQU_RS12160	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MAQU_RS12165	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MAQU_RS12180	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MAQU_RS12185	COG0305	Participates in initiation and elongation during chromosome replication
MAQU_RS12190	COG0359	binds to the 23S rRNA
MAQU_RS12200	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MAQU_RS12205	COG0360	Binds together with S18 to 16S ribosomal RNA
MAQU_RS12215	COG0557	exoribonuclease II activity
MAQU_RS12240	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
MAQU_RS12260	COG4584	PFAM Integrase catalytic
MAQU_RS12265	COG1484	DNA-dependent DNA replication
MAQU_RS12275	COG1960	acyl-CoA dehydrogenase activity
MAQU_RS12285	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MAQU_RS12290	COG0205	6-phosphofructokinase activity
MAQU_RS12295	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
MAQU_RS12310	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MAQU_RS12315	COG3706	GGDEF domain
MAQU_RS12320	COG0321	lipoyl(octanoyl) transferase activity
MAQU_RS12325	COG2921	Belongs to the UPF0250 family
MAQU_RS12330	COG1686	Belongs to the peptidase S11 family
MAQU_RS12340	COG0772	Belongs to the SEDS family
MAQU_RS12345	COG0768	penicillin binding
MAQU_RS12350	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MAQU_RS12360	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MAQU_RS12365	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MAQU_RS12380	COG0586	Pfam SNARE associated Golgi protein
MAQU_RS12395	COG0129	dihydroxy-acid dehydratase activity
MAQU_RS12420	COG0596	Alpha beta hydrolase
MAQU_RS12440	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MAQU_RS12445	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MAQU_RS12450	COG0730	response to heat
MAQU_RS12465	COG0142	geranyltranstransferase activity
MAQU_RS12470	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MAQU_RS12475	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MAQU_RS12480	COG0315	cyclic pyranopterin monophosphate synthase activity
MAQU_RS12485	COG0494	nUDIX hydrolase
MAQU_RS12490	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MAQU_RS12495	COG0653	protein targeting
MAQU_RS12500	COG0739	heme binding
MAQU_RS12510	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
MAQU_RS12525	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
MAQU_RS12530	COG1181	Belongs to the D-alanine--D-alanine ligase family
MAQU_RS12535	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MAQU_RS12540	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MAQU_RS12545	COG0772	Belongs to the SEDS family
MAQU_RS12550	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MAQU_RS12555	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MAQU_RS12560	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MAQU_RS12565	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MAQU_RS12575	COG3116	cell division
MAQU_RS12580	COG0275	rRNA processing
MAQU_RS12585	COG2001	Belongs to the MraZ family
MAQU_RS12595	COG3107	peptidoglycan biosynthetic process
MAQU_RS12600	COG0792	nuclease activity
MAQU_RS12605	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
MAQU_RS12610	COG2969	positive regulation of protein catabolic process
MAQU_RS12615	COG0625	glutathione transferase activity
MAQU_RS12620	COG2857	Cytochrome c1
MAQU_RS12625	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
MAQU_RS12630	COG0723	plastoquinol--plastocyanin reductase activity
MAQU_RS12635	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
MAQU_RS12640	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MAQU_RS12645	COG0084	hydrolase, TatD family'
MAQU_RS12650	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MAQU_RS12665	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MAQU_RS12695	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MAQU_RS12710	COG0494	nUDIX hydrolase
MAQU_RS12725	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MAQU_RS12725	COG0047	phosphoribosylformylglycinamidine synthase activity
MAQU_RS12730	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
MAQU_RS12735	COG2137	regulation of response to DNA damage stimulus
MAQU_RS12750	COG0183	Belongs to the thiolase family
MAQU_RS12755	COG1024	Enoyl-CoA hydratase
MAQU_RS12755	COG1250	3-hydroxyacyl-CoA dehydrogenase
MAQU_RS12760	COG0793	Belongs to the peptidase S41A family
MAQU_RS12770	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
MAQU_RS12775	COG0402	S-adenosylhomocysteine deaminase activity
MAQU_RS12780	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MAQU_RS12785	COG0546	phosphoglycolate phosphatase activity
MAQU_RS12790	COG1028	Short-chain dehydrogenase reductase Sdr
MAQU_RS12800	COG3022	response to hydroperoxide
MAQU_RS12810	COG2974	May be involved in recombination
MAQU_RS12815	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MAQU_RS12815	COG1042	CoA-binding domain protein
MAQU_RS12815	COG0045	succinate-CoA ligase (ADP-forming) activity
MAQU_RS12820	COG0123	including yeast histone deacetylase and acetoin utilization protein
MAQU_RS12830	COG0418	dihydroorotase activity
MAQU_RS12835	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MAQU_RS12840	COG4221	oxidoreductase activity
MAQU_RS12865	COG0701	Predicted permease
MAQU_RS12870	COG0625	glutathione transferase activity
MAQU_RS12930	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MAQU_RS12950	COG0009	L-threonylcarbamoyladenylate synthase
MAQU_RS12955	COG0271	Belongs to the BolA IbaG family
MAQU_RS12960	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MAQU_RS12965	COG0745	RESPONSE REGULATOR receiver
MAQU_RS12975	COG5002	protein histidine kinase activity
MAQU_RS12990	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MAQU_RS12995	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MAQU_RS13000	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MAQU_RS13005	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MAQU_RS13010	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MAQU_RS13030	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
MAQU_RS13040	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MAQU_RS13045	COG0233	cytoplasmic translational termination
MAQU_RS13050	COG0528	UMP kinase activity
MAQU_RS13055	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MAQU_RS13060	COG0052	Belongs to the universal ribosomal protein uS2 family
MAQU_RS13070	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
MAQU_RS13075	COG0436	Aminotransferase
MAQU_RS13080	COG1393	Belongs to the ArsC family
MAQU_RS13085	COG2171	N-acyltransferase activity
MAQU_RS13090	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MAQU_RS13095	COG2900	Belongs to the SlyX family
MAQU_RS13120	COG0346	lactoylglutathione lyase activity
MAQU_RS13135	COG3209	COG3209 Rhs family protein
MAQU_RS13135	COG3209	COG3209 Rhs family protein
MAQU_RS13150	COG0366	Alpha amylase catalytic
MAQU_RS13155	COG1215	transferase activity, transferring glycosyl groups
MAQU_RS13165	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
MAQU_RS13170	COG2211	Major facilitator Superfamily
MAQU_RS13185	COG0366	Alpha amylase catalytic
MAQU_RS13190	COG1215	transferase activity, transferring glycosyl groups
MAQU_RS13200	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
MAQU_RS13205	COG2211	Major facilitator Superfamily
MAQU_RS13220	COG0366	Alpha amylase catalytic
MAQU_RS13225	COG1215	transferase activity, transferring glycosyl groups
MAQU_RS13235	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
MAQU_RS13245	COG1666	GTP binding
MAQU_RS13250	COG0745	RESPONSE REGULATOR receiver
MAQU_RS13260	COG0137	argininosuccinate synthase activity
MAQU_RS13270	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
MAQU_RS13270	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
MAQU_RS13275	COG1334	flagellar protein FlaG
MAQU_RS13320	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MAQU_RS13325	COG2925	Exonuclease
MAQU_RS13340	COG2201	protein-glutamate methylesterase activity
MAQU_RS13345	COG3706	GGDEF domain
MAQU_RS13355	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
MAQU_RS13360	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
MAQU_RS13380	COG0438	transferase activity, transferring glycosyl groups
MAQU_RS13415	COG3273	potassium ion transport
MAQU_RS13415	COG0471	metal ion transport
MAQU_RS13420	COG0529	Catalyzes the synthesis of activated sulfate
MAQU_RS13425	COG2895	sulfate adenylyltransferase (ATP) activity
MAQU_RS13430	COG0175	sulfate reduction
MAQU_RS13505	COG4964	Belongs to the GSP D family
MAQU_RS13550	COG1459	type II secretion system
MAQU_RS13555	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MAQU_RS13575	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
MAQU_RS13620	COG4584	PFAM Integrase catalytic
MAQU_RS13625	COG1484	DNA-dependent DNA replication
MAQU_RS13675	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MAQU_RS13680	COG3657	addiction module killer protein
MAQU_RS13715	COG4969	Belongs to the N-Me-Phe pilin family
MAQU_RS13730	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
MAQU_RS13735	COG0237	dephospho-CoA kinase activity
MAQU_RS13745	COG1720	tRNA m6t6A37 methyltransferase activity
MAQU_RS13750	COG2205	protein histidine kinase activity
MAQU_RS13750	COG0784	Response regulator, receiver
MAQU_RS13750	COG5002	protein histidine kinase activity
MAQU_RS13755	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
MAQU_RS13775	COG0204	Acyl-transferase
MAQU_RS13780	COG2197	response regulator
MAQU_RS13795	COG0183	Belongs to the thiolase family
MAQU_RS13800	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
MAQU_RS13815	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MAQU_RS13820	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MAQU_RS13825	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
MAQU_RS13830	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MAQU_RS13835	COG5007	Belongs to the BolA IbaG family
MAQU_RS13850	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MAQU_RS13855	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MAQU_RS13860	COG1127	ABC transporter
MAQU_RS13870	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
MAQU_RS13885	COG1137	ATPase activity
MAQU_RS13905	COG1660	Displays ATPase and GTPase activities
MAQU_RS13910	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
MAQU_RS13915	COG2239	Acts as a magnesium transporter
MAQU_RS13920	COG3028	Belongs to the UPF0307 family
MAQU_RS13925	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MAQU_RS13950	COG1792	Involved in formation and maintenance of cell shape
MAQU_RS13955	COG1077	Cell shape determining protein MreB Mrl
MAQU_RS13965	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MAQU_RS13970	COG0154	amidase activity
MAQU_RS13975	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MAQU_RS13980	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MAQU_RS13990	COG0175	sulfate reduction
MAQU_RS14005	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MAQU_RS14010	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MAQU_RS14015	COG1702	phosphate starvation-inducible protein PhoH
MAQU_RS14020	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MAQU_RS14025	COG4535	Mg2 and Co2 transporter CorC
MAQU_RS14030	COG0815	Transfers the fatty acyl group on membrane lipoproteins
MAQU_RS14040	COG0495	leucyl-tRNA aminoacylation
MAQU_RS14050	COG1466	dna polymerase III delta subunit
MAQU_RS14065	COG1960	acyl-CoA dehydrogenase activity
MAQU_RS14070	COG1960	acyl-CoA dehydrogenase activity
MAQU_RS14085	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
MAQU_RS14095	COG0156	8-amino-7-oxononanoate synthase activity
MAQU_RS14100	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MAQU_RS14105	COG1040	competence protein
MAQU_RS14120	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MAQU_RS14130	COG4106	trans-aconitate 2-methyltransferase activity
MAQU_RS14135	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MAQU_RS14140	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MAQU_RS14145	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MAQU_RS14150	COG0330	HflC and HflK could
MAQU_RS14155	COG0330	HflC and HflK could
MAQU_RS14160	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MAQU_RS14165	COG1923	regulation of RNA biosynthetic process
MAQU_RS14170	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MAQU_RS14180	COG0860	N-Acetylmuramoyl-L-alanine amidase
MAQU_RS14185	COG0802	atpase or kinase
MAQU_RS14190	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
MAQU_RS14190	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MAQU_RS14200	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
MAQU_RS14205	COG1162	GTPase activity
MAQU_RS14220	COG0688	phosphatidylethanolamine metabolic process
MAQU_RS14225	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
MAQU_RS14230	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MAQU_RS14235	COG1509	lysine 2,3-aminomutase activity
MAQU_RS14245	COG2200	EAL domain
MAQU_RS14250	COG0560	Phosphoserine phosphatase
MAQU_RS14250	COG3830	Belongs to the UPF0237 family
MAQU_RS14265	COG0840	transmembrane signaling receptor activity
MAQU_RS14270	COG2353	YceI-like domain
MAQU_RS14275	COG3038	cytochrome b561
MAQU_RS14280	COG2200	EAL domain
MAQU_RS14280	COG2199	diguanylate cyclase activity
MAQU_RS14285	COG0471	metal ion transport
MAQU_RS14285	COG3273	potassium ion transport
MAQU_RS14325	COG1309	transcriptional regulator
MAQU_RS14335	COG1028	Short-chain dehydrogenase reductase Sdr
MAQU_RS14340	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MAQU_RS14345	COG1960	acyl-CoA dehydrogenase activity
MAQU_RS14360	COG0300	oxidoreductase activity
MAQU_RS14365	COG0318	PFAM AMP-dependent synthetase and ligase
MAQU_RS14380	COG2860	membrane
MAQU_RS14385	COG2252	PERMEase
MAQU_RS14390	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MAQU_RS14395	COG0179	Fumarylacetoacetate (FAA) hydrolase
MAQU_RS14400	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MAQU_RS14405	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MAQU_RS14410	COG0277	FAD linked oxidase domain protein
MAQU_RS14415	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MAQU_RS14425	COG2885	chlorophyll binding
MAQU_RS14440	COG2827	Endonuclease containing a URI domain
MAQU_RS14465	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MAQU_RS14480	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
MAQU_RS14535	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MAQU_RS14540	COG1024	Enoyl-CoA hydratase
MAQU_RS14545	COG1960	acyl-CoA dehydrogenase activity
MAQU_RS14550	COG2207	Transcriptional regulator
MAQU_RS14550	COG0662	Cupin 2, conserved barrel domain protein
MAQU_RS14555	COG0446	pyridine nucleotide-disulphide oxidoreductase
MAQU_RS14555	COG1902	pentaerythritol trinitrate reductase activity
MAQU_RS14560	COG2111	Na H antiporter
MAQU_RS14560	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MAQU_RS14565	COG1006	Multisubunit Na H antiporter MnhC subunit
MAQU_RS14570	COG0651	ATP synthesis coupled electron transport
MAQU_RS14575	COG1863	multisubunit Na H antiporter MnhE subunit
MAQU_RS14580	COG2212	antiporter activity
MAQU_RS14585	COG1320	monovalent cation:proton antiporter activity
MAQU_RS14590	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MAQU_RS14590	COG2111	Na H antiporter
MAQU_RS14595	COG2111	Na H antiporter
MAQU_RS14600	COG1006	Multisubunit Na H antiporter MnhC subunit
MAQU_RS14605	COG0651	ATP synthesis coupled electron transport
MAQU_RS14610	COG1863	multisubunit Na H antiporter MnhE subunit
MAQU_RS14615	COG2212	antiporter activity
MAQU_RS14620	COG1320	monovalent cation:proton antiporter activity
MAQU_RS14625	COG3123	guanosine phosphorylase activity
MAQU_RS14630	COG0318	PFAM AMP-dependent synthetase and ligase
MAQU_RS14635	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MAQU_RS14640	COG0023	Translation Initiation Factor
MAQU_RS14650	COG1739	Uncharacterized protein family UPF0029
MAQU_RS14665	COG0745	RESPONSE REGULATOR receiver
MAQU_RS14685	COG3360	Dodecin
MAQU_RS14715	COG0733	neurotransmitter:sodium symporter activity
MAQU_RS14730	COG0488	(ABC) transporter
MAQU_RS14740	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MAQU_RS14755	COG0583	DNA-binding transcription factor activity
MAQU_RS14785	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
MAQU_RS14815	COG3290	protein histidine kinase activity
MAQU_RS14835	COG0697	spore germination
MAQU_RS14845	COG1301	dicarboxylic acid transport
MAQU_RS14850	COG0741	lytic transglycosylase activity
MAQU_RS14850	COG1196	nuclear chromosome segregation
MAQU_RS14850	COG0739	heme binding
MAQU_RS14870	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MAQU_RS14875	COG1607	acyl-coa hydrolase
MAQU_RS14895	COG2203	Gaf domain
MAQU_RS14895	COG4251	negative regulation of phosphorylation
MAQU_RS14895	COG3706	GGDEF domain
MAQU_RS14895	COG5001	Diguanylate cyclase
MAQU_RS14905	COG0840	transmembrane signaling receptor activity
MAQU_RS14915	COG0702	epimerase
MAQU_RS14925	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MAQU_RS15000	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MAQU_RS15035	COG4303	Ethanolamine ammonia lyase large subunit
MAQU_RS15040	COG4302	ethanolamine ammonia-lyase activity
MAQU_RS15050	COG0702	epimerase
MAQU_RS15065	COG0625	glutathione transferase activity
MAQU_RS15095	COG1285	pathogenesis
MAQU_RS15100	COG0628	permease
MAQU_RS15105	COG1278	Cold shock
MAQU_RS15110	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MAQU_RS15110	COG2169	Transcriptional regulator
MAQU_RS15125	COG1061	Type III restriction enzyme res subunit
MAQU_RS15140	COG1047	Peptidyl-prolyl cis-trans
MAQU_RS15165	COG0653	protein targeting
MAQU_RS15215	COG3781	membrane
MAQU_RS15230	COG3609	addiction module antidote protein, CC2985 family
MAQU_RS15235	COG1484	DNA-dependent DNA replication
MAQU_RS15240	COG4584	PFAM Integrase catalytic
MAQU_RS15280	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
MAQU_RS15285	COG0830	nickel cation binding
MAQU_RS15290	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
MAQU_RS15295	COG0804	urea catabolic process
MAQU_RS15300	COG0832	Belongs to the urease beta subunit family
MAQU_RS15305	COG0831	urea catabolic process
MAQU_RS15310	COG0829	nickel cation binding
MAQU_RS15320	COG0411	ABC transporter
MAQU_RS15340	COG1555	photosystem II stabilization
MAQU_RS15340	COG1596	polysaccharide export
MAQU_RS15370	COG0438	transferase activity, transferring glycosyl groups
MAQU_RS15390	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
MAQU_RS15390	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MAQU_RS15395	COG2070	2-Nitropropane dioxygenase
MAQU_RS15430	COG0789	Transcriptional regulator
MAQU_RS15435	COG0484	heat shock protein binding
MAQU_RS15450	COG2814	Major facilitator Superfamily
MAQU_RS15480	COG2308	Evidence 4 Homologs of previously reported genes of
MAQU_RS15480	COG2307	Protein conserved in bacteria
MAQU_RS15495	COG2308	Evidence 4 Homologs of previously reported genes of
MAQU_RS15510	COG0126	phosphoglycerate kinase activity
MAQU_RS15515	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MAQU_RS15520	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MAQU_RS15530	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MAQU_RS15535	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
MAQU_RS15540	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
MAQU_RS15545	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MAQU_RS15550	COG0765	amino acid transport
MAQU_RS15570	COG1385	rRNA (uridine-N3-)-methyltransferase activity
MAQU_RS15585	COG1295	ribonuclease BN
MAQU_RS15590	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MAQU_RS15595	COG0500	methyltransferase
MAQU_RS15600	COG2766	serine protein kinase
MAQU_RS15605	COG2718	Belongs to the UPF0229 family
MAQU_RS15610	COG2719	SpoVR family
MAQU_RS15620	COG0745	RESPONSE REGULATOR receiver
MAQU_RS15635	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MAQU_RS15640	COG1346	cytolysis
MAQU_RS15650	COG0385	Bile acid
MAQU_RS15675	COG1959	2 iron, 2 sulfur cluster binding
MAQU_RS15680	COG2832	Protein of unknown function (DUF454)
MAQU_RS15690	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MAQU_RS15700	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
MAQU_RS15720	COG3901	Regulator of nitric oxide reductase transcription
MAQU_RS15720	COG0348	domain, Protein
MAQU_RS15735	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MAQU_RS15740	COG2181	nitrate reductase activity
MAQU_RS15745	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
MAQU_RS15755	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MAQU_RS15765	COG3850	Histidine kinase
MAQU_RS15770	COG2197	response regulator
MAQU_RS15775	COG3154	lipid carrier protein
MAQU_RS15785	COG3189	MarR family transcriptional regulator
MAQU_RS15810	COG0826	peptidase U32
MAQU_RS15815	COG0826	peptidase U32
MAQU_RS15820	COG0840	transmembrane signaling receptor activity
MAQU_RS15830	COG3046	protein related to deoxyribodipyrimidine photolyase
MAQU_RS15840	COG0546	phosphoglycolate phosphatase activity
MAQU_RS15845	COG0415	Belongs to the DNA photolyase family
MAQU_RS15855	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MAQU_RS15890	COG2010	Cytochrome c
MAQU_RS15895	COG3256	nitric oxide reductase
MAQU_RS15925	COG0714	Associated with various cellular activities
MAQU_RS15940	COG2010	Cytochrome c
MAQU_RS15970	COG0535	radical SAM domain protein
MAQU_RS15975	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MAQU_RS15975	COG1648	precorrin-2 dehydrogenase activity
MAQU_RS15990	COG0655	NAD(P)H dehydrogenase (quinone) activity
MAQU_RS15995	COG1272	protein, Hemolysin III
MAQU_RS16005	COG2223	nitrite transmembrane transporter activity
MAQU_RS16015	COG2223	nitrite transmembrane transporter activity
MAQU_RS16055	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MAQU_RS16070	COG0826	peptidase U32
MAQU_RS16075	COG0719	Fe-S assembly protein
MAQU_RS16080	COG0396	ATPase activity
MAQU_RS16085	COG0719	Fe-S assembly protein
MAQU_RS16090	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MAQU_RS16095	COG0316	Belongs to the HesB IscA family
MAQU_RS16100	COG2151	metal-sulfur cluster biosynthetic enzyme
MAQU_RS16105	COG2166	iron-sulfur cluster assembly
MAQU_RS16120	COG0617	tRNA 3'-terminal CCA addition
MAQU_RS16125	COG1028	Short-chain dehydrogenase reductase Sdr
MAQU_RS16130	COG0183	Belongs to the thiolase family
MAQU_RS16135	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
MAQU_RS16140	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
MAQU_RS16145	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MAQU_RS16150	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MAQU_RS16155	COG4942	peptidase
MAQU_RS16160	COG0793	Belongs to the peptidase S41A family
MAQU_RS16170	COG0107	imidazoleglycerol-phosphate synthase activity
MAQU_RS16175	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MAQU_RS16180	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MAQU_RS16185	COG0131	Imidazoleglycerol-phosphate dehydratase
MAQU_RS16205	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
MAQU_RS16220	COG1484	DNA-dependent DNA replication
MAQU_RS16225	COG4584	PFAM Integrase catalytic
MAQU_RS16245	COG2801	Transposase and inactivated derivatives
MAQU_RS16260	COG4584	PFAM Integrase catalytic
MAQU_RS16265	COG1484	DNA-dependent DNA replication
MAQU_RS16370	COG4974	Belongs to the 'phage' integrase family
MAQU_RS16410	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MAQU_RS16420	COG0642	Histidine kinase
MAQU_RS16430	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MAQU_RS16460	COG0633	Ferredoxin
MAQU_RS16460	COG0543	2 iron, 2 sulfur cluster binding
MAQU_RS16500	COG2207	Transcriptional regulator
MAQU_RS16500	COG4753	response regulator
MAQU_RS16575	COG0785	Cytochrome C biogenesis protein
MAQU_RS16590	COG0427	acetyl-CoA hydrolase
MAQU_RS16615	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MAQU_RS16665	COG0840	transmembrane signaling receptor activity
MAQU_RS16670	COG0840	transmembrane signaling receptor activity
MAQU_RS16670	COG0840	transmembrane signaling receptor activity
MAQU_RS16705	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MAQU_RS16715	COG1999	signal sequence binding
MAQU_RS16730	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MAQU_RS16765	COG1280	lysine exporter protein (LysE YggA)
MAQU_RS16785	COG4771	TonB-dependent receptor
MAQU_RS16790	COG0583	DNA-binding transcription factor activity
MAQU_RS16795	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MAQU_RS16800	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MAQU_RS16805	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MAQU_RS16810	COG1120	ATPase activity
MAQU_RS16815	COG2814	Major facilitator Superfamily
MAQU_RS16825	COG0247	lactate metabolic process
MAQU_RS16830	COG0277	FAD linked oxidase domain protein
MAQU_RS16835	COG0277	FAD linked oxidase domain protein
MAQU_RS16845	COG2186	Transcriptional regulator
MAQU_RS16855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MAQU_RS16865	COG4160	amino acid transport
MAQU_RS16875	COG2988	succinylglutamate desuccinylase activity
MAQU_RS16895	COG3724	N-succinylarginine dihydrolase activity
MAQU_RS16900	COG1012	belongs to the aldehyde dehydrogenase family
MAQU_RS16915	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MAQU_RS16930	COG1960	acyl-CoA dehydrogenase activity
MAQU_RS16965	COG1509	lysine 2,3-aminomutase activity
MAQU_RS16980	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MAQU_RS17040	COG1185	polyribonucleotide nucleotidyltransferase activity
MAQU_RS17045	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MAQU_RS17050	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MAQU_RS17055	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MAQU_RS17060	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MAQU_RS17065	COG0195	Participates in both transcription termination and antitermination
MAQU_RS17070	COG0779	Required for maturation of 30S ribosomal subunits
MAQU_RS17085	COG0149	triose-phosphate isomerase activity
MAQU_RS17090	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MAQU_RS17095	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MAQU_RS17100	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MAQU_RS17110	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MAQU_RS17115	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
MAQU_RS17125	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
MAQU_RS17130	COG0484	heat shock protein binding
MAQU_RS17135	COG0443	Heat shock 70 kDa protein
MAQU_RS17140	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MAQU_RS17145	COG0497	DNA recombination
MAQU_RS17155	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MAQU_RS17160	COG2914	Belongs to the UPF0125 (RnfH) family
MAQU_RS17165	COG2867	negative regulation of translational initiation
MAQU_RS17170	COG0733	neurotransmitter:sodium symporter activity
MAQU_RS17175	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MAQU_RS17200	COG2026	Addiction module toxin, RelE StbE family
MAQU_RS17205	COG0582	viral genome integration into host DNA
MAQU_RS17220	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
MAQU_RS17235	COG0732	type I restriction modification DNA specificity domain
MAQU_RS17245	COG1569	PIN domain
MAQU_RS17250	COG3311	Transcriptional regulator
MAQU_RS17255	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
MAQU_RS17260	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MAQU_RS17280	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MAQU_RS17290	COG0542	response to heat
MAQU_RS17295	COG0071	Belongs to the small heat shock protein (HSP20) family
MAQU_RS17305	COG0784	Response regulator, receiver
MAQU_RS17305	COG0835	chemotaxis
MAQU_RS17310	COG0028	Belongs to the TPP enzyme family
MAQU_RS17315	COG0579	oxidoreductase
MAQU_RS17335	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MAQU_RS17365	COG0604	alcohol dehydrogenase
MAQU_RS17370	COG1309	transcriptional regulator
MAQU_RS17400	COG2226	methyltransferase
MAQU_RS17410	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MAQU_RS17415	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MAQU_RS17420	COG0140	phosphoribosyl-ATP diphosphatase activity
MAQU_RS17425	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MAQU_RS17430	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MAQU_RS17440	COG1385	rRNA (uridine-N3-)-methyltransferase activity
MAQU_RS17445	COG2354	Protein conserved in bacteria
MAQU_RS17450	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MAQU_RS17455	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MAQU_RS17460	COG0006	proline dipeptidase activity
MAQU_RS17465	COG3079	Belongs to the UPF0149 family
MAQU_RS17480	COG4181	ATPase activity
MAQU_RS17500	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MAQU_RS17505	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MAQU_RS17510	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MAQU_RS17515	COG1960	acyl-CoA dehydrogenase activity
MAQU_RS17520	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
MAQU_RS17530	COG3300	MHYT domain
MAQU_RS17530	COG5001	Diguanylate cyclase
MAQU_RS17540	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
MAQU_RS17545	COG0511	ligase activity, forming carbon-carbon bonds
MAQU_RS17555	COG2264	protein methyltransferase activity
MAQU_RS17580	COG0151	Belongs to the GarS family
MAQU_RS17590	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MAQU_RS17590	COG4651	solute:proton antiporter activity
MAQU_RS17595	COG1262	PFAM Formylglycine-generating sulfatase enzyme
MAQU_RS17615	COG0490	domain, Protein
MAQU_RS17615	COG0471	metal ion transport
MAQU_RS17680	COG0659	secondary active sulfate transmembrane transporter activity
MAQU_RS17705	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
MAQU_RS17715	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
MAQU_RS17730	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MAQU_RS17755	COG0783	Belongs to the Dps family
MAQU_RS17765	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MAQU_RS17770	COG1280	lysine exporter protein (LysE YggA)
MAQU_RS17775	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MAQU_RS17810	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MAQU_RS17835	COG0483	inositol monophosphate 1-phosphatase activity
MAQU_RS17840	COG1309	transcriptional regulator
MAQU_RS17845	COG2022	thiamine diphosphate biosynthetic process
MAQU_RS17855	COG2363	Small membrane protein
MAQU_RS17860	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
MAQU_RS17865	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
MAQU_RS17870	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
MAQU_RS17875	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MAQU_RS17880	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
MAQU_RS17885	COG3178	'Phosphotransferase
MAQU_RS17890	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
MAQU_RS17905	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
MAQU_RS17910	COG0546	phosphoglycolate phosphatase activity
MAQU_RS17920	COG0512	Glutamine amidotransferase of anthranilate synthase
MAQU_RS17925	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MAQU_RS17930	COG0134	indole-3-glycerol-phosphate synthase activity
MAQU_RS17955	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MAQU_RS17965	COG1082	Xylose isomerase domain protein TIM barrel
MAQU_RS17980	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MAQU_RS17990	COG4771	TonB-dependent receptor
MAQU_RS18065	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
MAQU_RS18085	COG1765	OsmC-like protein
MAQU_RS18090	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
MAQU_RS18100	COG3954	Phosphoribulokinase
MAQU_RS18115	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
MAQU_RS18115	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
MAQU_RS18130	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
MAQU_RS18145	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MAQU_RS18150	COG2003	Belongs to the UPF0758 family
MAQU_RS18155	COG0227	Belongs to the bacterial ribosomal protein bL28 family
MAQU_RS18160	COG0267	Belongs to the bacterial ribosomal protein bL33 family
MAQU_RS18180	COG0218	Necessary for normal cell division and for the maintenance of normal septation
MAQU_RS18205	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MAQU_RS18235	COG1309	transcriptional regulator
MAQU_RS18240	COG1960	acyl-CoA dehydrogenase activity
MAQU_RS18250	COG0076	glutamate decarboxylase activity
MAQU_RS18260	COG0306	phosphate transporter
MAQU_RS18275	COG2203	Gaf domain
MAQU_RS18275	COG4251	negative regulation of phosphorylation
MAQU_RS18275	COG3706	GGDEF domain
MAQU_RS18275	COG5001	Diguanylate cyclase
MAQU_RS18280	COG1946	Acyl-CoA thioesterase
MAQU_RS18295	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
MAQU_RS18300	COG3161	chorismate lyase activity
MAQU_RS18305	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
MAQU_RS18320	COG0745	RESPONSE REGULATOR receiver
MAQU_RS18325	COG2951	lytic endotransglycosylase activity
MAQU_RS18340	COG1187	pseudouridine synthase activity
MAQU_RS18345	COG0252	asparaginase activity
MAQU_RS18350	COG1686	Belongs to the peptidase S11 family
MAQU_RS18355	COG5001	Diguanylate cyclase
MAQU_RS18355	COG4251	negative regulation of phosphorylation
MAQU_RS18355	COG3706	GGDEF domain
MAQU_RS18355	COG2203	Gaf domain
MAQU_RS18365	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
MAQU_RS18370	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
MAQU_RS18390	COG1278	Cold shock
MAQU_RS18395	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MAQU_RS18400	COG1960	acyl-CoA dehydrogenase activity
MAQU_RS18405	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MAQU_RS18410	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
MAQU_RS18425	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
MAQU_RS18430	COG0668	transmembrane transport
MAQU_RS18440	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MAQU_RS18445	COG0537	adenosine 5'-monophosphoramidase activity
MAQU_RS18450	COG1253	flavin adenine dinucleotide binding
MAQU_RS18455	COG0704	Plays a role in the regulation of phosphate uptake
MAQU_RS18460	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MAQU_RS18465	COG0581	inorganic phosphate transmembrane transporter activity
MAQU_RS18470	COG0573	inorganic phosphate transmembrane transporter activity
MAQU_RS18480	COG1607	acyl-coa hydrolase
MAQU_RS18495	COG0390	transport system, permease component
MAQU_RS18500	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
MAQU_RS18515	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MAQU_RS18520	COG0640	Transcriptional regulator
MAQU_RS18525	COG0431	NADPH-dependent FMN reductase
MAQU_RS18530	COG0798	PFAM Bile acid sodium symporter
MAQU_RS18535	COG1968	undecaprenyl-diphosphatase activity
MAQU_RS18540	COG0210	DNA helicase
MAQU_RS18570	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MAQU_RS18570	COG0301	tRNA thio-modification
MAQU_RS18575	COG1611	Belongs to the LOG family
MAQU_RS18585	COG1024	Enoyl-CoA hydratase
MAQU_RS18595	COG1444	tRNA N-acetyltransferase activity
MAQU_RS18600	COG0210	DNA helicase
MAQU_RS18615	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
MAQU_RS18630	COG0084	hydrolase, TatD family'
MAQU_RS18655	COG2431	L-lysine efflux transmembrane transporter activity
MAQU_RS18665	COG2204	response regulator
MAQU_RS18670	COG0745	RESPONSE REGULATOR receiver
MAQU_RS18685	COG3437	response regulator, receiver
MAQU_RS18685	COG4999	Histidine kinase
MAQU_RS18685	COG3850	Histidine kinase
MAQU_RS18685	COG2205	protein histidine kinase activity
MAQU_RS18700	COG5002	protein histidine kinase activity
MAQU_RS18700	COG2198	Histidine kinase
MAQU_RS18700	COG0784	Response regulator, receiver
MAQU_RS18705	COG3437	response regulator, receiver
MAQU_RS18750	COG0745	RESPONSE REGULATOR receiver
MAQU_RS18755	COG2205	protein histidine kinase activity
MAQU_RS18770	COG3706	GGDEF domain
MAQU_RS18795	COG4067	protein conserved in archaea
MAQU_RS18795	COG0189	ligase activity
MAQU_RS18800	COG1793	dna ligase
MAQU_RS18835	COG3789	protein conserved in bacteria
MAQU_RS18865	COG4584	PFAM Integrase catalytic
MAQU_RS18870	COG1484	DNA-dependent DNA replication
MAQU_RS18885	COG3039	Transposase
MAQU_RS18915	COG3501	Rhs element vgr protein
MAQU_RS18935	COG3829	transcription factor binding
MAQU_RS19025	COG3622	Belongs to the hyi family
MAQU_RS19030	COG2084	Dehydrogenase
MAQU_RS19040	COG2177	Part of the ABC transporter FtsEX involved in
MAQU_RS19045	COG2884	Cell division ATP-binding protein ftsE
MAQU_RS19050	COG0552	protein localization to endoplasmic reticulum
MAQU_RS19055	COG0742	ribosomal rna small subunit methyltransferase
MAQU_RS19065	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
MAQU_RS19075	COG1011	Hydrolase
MAQU_RS19080	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
MAQU_RS19085	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MAQU_RS19090	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
MAQU_RS19100	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
MAQU_RS19100	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
MAQU_RS19125	COG0540	Belongs to the ATCase OTCase family
MAQU_RS19130	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MAQU_RS19135	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MAQU_RS19140	COG1678	Uncharacterized ACR, COG1678
MAQU_RS19150	COG0189	ligase activity
MAQU_RS19170	COG0840	transmembrane signaling receptor activity
MAQU_RS19185	COG2201	protein-glutamate methylesterase activity
MAQU_RS19195	COG0735	belongs to the Fur family
MAQU_RS19200	COG1121	(ABC) transporter
MAQU_RS19205	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MAQU_RS19230	COG0302	gtp cyclohydrolase
MAQU_RS19235	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MAQU_RS19240	COG1832	CoA-binding protein
MAQU_RS19260	COG0789	Transcriptional regulator
MAQU_RS19265	COG2217	Heavy metal translocating P-type atpase
MAQU_RS19290	COG0204	Acyl-transferase
MAQU_RS19300	COG0583	DNA-binding transcription factor activity
MAQU_RS19305	COG2814	Major facilitator Superfamily
MAQU_RS19325	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MAQU_RS19335	COG3608	succinylglutamate desuccinylase aspartoacylase
MAQU_RS19340	COG0697	spore germination
MAQU_RS19350	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
MAQU_RS19370	COG1960	acyl-CoA dehydrogenase activity
MAQU_RS19390	COG2095	MarC family integral membrane protein
MAQU_RS19395	COG1187	pseudouridine synthase activity
MAQU_RS19440	COG3047	cAMP biosynthetic process
MAQU_RS19445	COG0513	Belongs to the DEAD box helicase family
MAQU_RS19450	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MAQU_RS19480	COG3039	Transposase
MAQU_RS19505	COG3634	alkyl hydroperoxide reductase activity
MAQU_RS19510	COG0450	alkyl hydroperoxide reductase
MAQU_RS19530	COG1309	transcriptional regulator
MAQU_RS19535	COG1024	Enoyl-CoA hydratase
MAQU_RS19550	COG3706	GGDEF domain
MAQU_RS19580	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MAQU_RS19590	COG1917	Cupin 2, conserved barrel domain protein
MAQU_RS19590	COG2207	Transcriptional regulator
MAQU_RS19600	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MAQU_RS19600	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MAQU_RS19625	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MAQU_RS19655	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MAQU_RS19655	COG0784	Response regulator, receiver
MAQU_RS19655	COG2198	Histidine kinase
MAQU_RS19655	COG2205	protein histidine kinase activity
MAQU_RS19670	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
MAQU_RS19675	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
MAQU_RS19680	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MAQU_RS19685	COG0355	proton-transporting ATP synthase activity, rotational mechanism
MAQU_RS19690	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MAQU_RS19695	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MAQU_RS19700	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MAQU_RS19705	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MAQU_RS19710	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MAQU_RS19720	COG0356	it plays a direct role in the translocation of protons across the membrane
MAQU_RS19725	COG3312	ion transport
MAQU_RS19730	COG1475	DNA binding
MAQU_RS19735	COG1192	Involved in chromosome partitioning
MAQU_RS19740	COG0357	Ribosomal RNA small subunit methyltransferase G
MAQU_RS19745	COG0445	tRNA wobble uridine modification
MAQU_RS19755	COG4943	cyclic-guanylate-specific phosphodiesterase activity
MAQU_RS19760	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MAQU_RS19775	COG1960	acyl-CoA dehydrogenase activity
MAQU_RS19780	COG5285	phytanoyl-CoA dioxygenase
MAQU_RS19790	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MAQU_RS19795	COG0706	membrane insertase activity
MAQU_RS19800	COG0594	ribonuclease P activity
MAQU_RS19825	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MAQU_RS19885	COG5265	(ABC) transporter
MAQU_RS20110	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MAQU_RS20455	COG2205	protein histidine kinase activity
MAQU_RS20455	COG0784	Response regulator, receiver
MAQU_RS20840	COG0243	molybdopterin cofactor binding
MAQU_RS20845	COG0243	molybdopterin cofactor binding
MAQU_RS21045	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MAQU_RS21345	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MAQU_RS21480	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
MAQU_RS21565	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
MAQU_RS21730	COG1388	LysM domain
MAQU_RS21730	COG1376	ErfK ybiS ycfS ynhG family protein
MAQU_RS21760	COG3263	regulation of cellular component size
MAQU_RS21800	COG2132	Multicopper oxidase
MAQU_RS22050	COG2146	nitrite reductase [NAD(P)H] activity
MAQU_RS22050	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MAQU_RS22110	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MAQU_RS22125	COG1741	Belongs to the pirin family
MAQU_RS22165	COG1216	Glycosyl transferase, family 2
MAQU_RS22165	COG0438	transferase activity, transferring glycosyl groups
MAQU_RS22170	COG1216	Glycosyl transferase, family 2