locus-tag	class	description
BKP64_RS00015	COG3154	lipid carrier protein
BKP64_RS00020	COG2197	response regulator
BKP64_RS00025	COG3850	Histidine kinase
BKP64_RS00035	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BKP64_RS00045	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BKP64_RS00050	COG2181	nitrate reductase activity
BKP64_RS00075	COG0348	domain, Protein
BKP64_RS00075	COG3901	Regulator of nitric oxide reductase transcription
BKP64_RS00095	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BKP64_RS00110	COG2169	Transcriptional regulator
BKP64_RS00110	COG1917	Cupin 2, conserved barrel domain protein
BKP64_RS00115	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BKP64_RS00120	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
BKP64_RS00130	COG2832	Protein of unknown function (DUF454)
BKP64_RS00135	COG1959	2 iron, 2 sulfur cluster binding
BKP64_RS00165	COG1346	cytolysis
BKP64_RS00170	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
BKP64_RS00175	COG2719	SpoVR family
BKP64_RS00180	COG2718	Belongs to the UPF0229 family
BKP64_RS00185	COG2766	serine protein kinase
BKP64_RS00190	COG0500	methyltransferase
BKP64_RS00195	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BKP64_RS00205	COG1295	ribonuclease BN
BKP64_RS00215	COG4399	Belongs to the UPF0754 family
BKP64_RS00220	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BKP64_RS00250	COG1126	abc transporter atp-binding protein
BKP64_RS00255	COG0765	amino acid transport
BKP64_RS00260	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BKP64_RS00265	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BKP64_RS00270	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BKP64_RS00275	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BKP64_RS00285	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BKP64_RS00290	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BKP64_RS00295	COG0126	phosphoglycerate kinase activity
BKP64_RS00310	COG0789	Transcriptional regulator
BKP64_RS00330	COG0840	transmembrane signaling receptor activity
BKP64_RS00335	COG2070	2-Nitropropane dioxygenase
BKP64_RS00340	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BKP64_RS00340	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BKP64_RS00345	COG1054	Belongs to the UPF0176 family
BKP64_RS00355	COG0438	transferase activity, transferring glycosyl groups
BKP64_RS00385	COG0697	spore germination
BKP64_RS00395	COG1139	Iron-sulfur cluster binding protein
BKP64_RS00400	COG0247	lactate metabolic process
BKP64_RS00405	COG1596	polysaccharide export
BKP64_RS00405	COG1555	photosystem II stabilization
BKP64_RS00430	COG0411	ABC transporter
BKP64_RS00440	COG0829	nickel cation binding
BKP64_RS00445	COG0831	urea catabolic process
BKP64_RS00450	COG0832	Belongs to the urease beta subunit family
BKP64_RS00455	COG0804	urea catabolic process
BKP64_RS00460	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
BKP64_RS00465	COG0830	nickel cation binding
BKP64_RS00470	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BKP64_RS00485	COG1196	nuclear chromosome segregation
BKP64_RS00500	COG1078	dGTPase activity
BKP64_RS00550	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
BKP64_RS00550	COG3264	Mechanosensitive ion channel
BKP64_RS00565	COG1028	Short-chain dehydrogenase reductase Sdr
BKP64_RS00570	COG0693	protein deglycase activity
BKP64_RS00580	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BKP64_RS00595	COG1061	Type III restriction enzyme res subunit
BKP64_RS00605	COG1047	Peptidyl-prolyl cis-trans
BKP64_RS00610	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BKP64_RS00610	COG1017	nitric oxide dioxygenase activity
BKP64_RS00635	COG2169	Transcriptional regulator
BKP64_RS00635	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BKP64_RS00650	COG1278	Cold shock
BKP64_RS00670	COG0625	glutathione transferase activity
BKP64_RS00675	COG1752	Esterase of the alpha-beta hydrolase superfamily
BKP64_RS00685	COG0702	epimerase
BKP64_RS00695	COG0484	heat shock protein binding
BKP64_RS00750	COG3384	dioxygenase
BKP64_RS00755	COG2814	Major facilitator Superfamily
BKP64_RS00760	COG1846	Transcriptional regulator
BKP64_RS00780	COG0179	Fumarylacetoacetate (FAA) hydrolase
BKP64_RS00790	COG3971	2-oxopent-4-enoate hydratase activity
BKP64_RS00815	COG0589	response to stress
BKP64_RS00825	COG0583	DNA-binding transcription factor activity
BKP64_RS00850	COG3243	poly(R)-hydroxyalkanoic acid synthase
BKP64_RS00855	COG1028	Short-chain dehydrogenase reductase Sdr
BKP64_RS00880	COG0653	protein targeting
BKP64_RS00890	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BKP64_RS00905	COG0583	DNA-binding transcription factor activity
BKP64_RS00925	COG4716	Myosin-crossreactive antigen
BKP64_RS00935	COG0459	protein refolding
BKP64_RS00950	COG0543	2 iron, 2 sulfur cluster binding
BKP64_RS00975	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
BKP64_RS00980	COG0298	carbon dioxide binding
BKP64_RS00995	COG2423	ornithine cyclodeaminase activity
BKP64_RS01000	COG3616	Alanine racemase, N-terminal domain
BKP64_RS01005	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BKP64_RS01010	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BKP64_RS01045	COG2814	Major facilitator Superfamily
BKP64_RS01055	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BKP64_RS01085	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BKP64_RS01100	COG0039	L-malate dehydrogenase activity
BKP64_RS01105	COG1607	acyl-coa hydrolase
BKP64_RS01115	COG1522	sequence-specific DNA binding
BKP64_RS01130	COG1984	allophanate hydrolase subunit 2
BKP64_RS01135	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BKP64_RS01140	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BKP64_RS01160	COG4336	lyase activity
BKP64_RS01180	COG1280	lysine exporter protein (LysE YggA)
BKP64_RS01195	COG0741	lytic transglycosylase activity
BKP64_RS01200	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BKP64_RS01205	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BKP64_RS01220	COG1301	dicarboxylic acid transport
BKP64_RS01235	COG0398	Pfam SNARE associated Golgi protein
BKP64_RS01245	COG0697	spore germination
BKP64_RS01250	COG2962	Rard protein
BKP64_RS01265	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BKP64_RS01270	COG0702	epimerase
BKP64_RS01290	COG0583	DNA-binding transcription factor activity
BKP64_RS01335	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BKP64_RS01365	COG0583	DNA-binding transcription factor activity
BKP64_RS01380	COG1234	tRNA 3'-trailer cleavage
BKP64_RS01385	COG0006	proline dipeptidase activity
BKP64_RS01390	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BKP64_RS01395	COG0488	(ABC) transporter
BKP64_RS01415	COG0733	neurotransmitter:sodium symporter activity
BKP64_RS01450	COG3360	Dodecin
BKP64_RS01470	COG0745	RESPONSE REGULATOR receiver
BKP64_RS01475	COG2205	protein histidine kinase activity
BKP64_RS01480	COG1739	Uncharacterized protein family UPF0029
BKP64_RS01490	COG0023	Translation Initiation Factor
BKP64_RS01495	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BKP64_RS01500	COG0318	PFAM AMP-dependent synthetase and ligase
BKP64_RS01505	COG3123	guanosine phosphorylase activity
BKP64_RS01510	COG1320	monovalent cation:proton antiporter activity
BKP64_RS01515	COG2212	antiporter activity
BKP64_RS01520	COG1863	multisubunit Na H antiporter MnhE subunit
BKP64_RS01525	COG0651	ATP synthesis coupled electron transport
BKP64_RS01530	COG1006	Multisubunit Na H antiporter MnhC subunit
BKP64_RS01535	COG2111	Na H antiporter
BKP64_RS01540	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BKP64_RS01540	COG2111	Na H antiporter
BKP64_RS01545	COG1320	monovalent cation:proton antiporter activity
BKP64_RS01550	COG2212	antiporter activity
BKP64_RS01555	COG1863	multisubunit Na H antiporter MnhE subunit
BKP64_RS01560	COG0651	ATP synthesis coupled electron transport
BKP64_RS01565	COG1006	Multisubunit Na H antiporter MnhC subunit
BKP64_RS01570	COG2111	Na H antiporter
BKP64_RS01570	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BKP64_RS01575	COG1902	pentaerythritol trinitrate reductase activity
BKP64_RS01575	COG0446	pyridine nucleotide-disulphide oxidoreductase
BKP64_RS01580	COG1960	acyl-CoA dehydrogenase activity
BKP64_RS01640	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BKP64_RS01655	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BKP64_RS01680	COG2885	chlorophyll binding
BKP64_RS01685	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BKP64_RS01690	COG0277	FAD linked oxidase domain protein
BKP64_RS01700	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BKP64_RS01720	COG1414	Transcriptional regulator
BKP64_RS01725	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BKP64_RS01730	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BKP64_RS01735	COG0179	Fumarylacetoacetate (FAA) hydrolase
BKP64_RS01740	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BKP64_RS01745	COG2252	PERMEase
BKP64_RS01750	COG2860	membrane
BKP64_RS01765	COG0318	PFAM AMP-dependent synthetase and ligase
BKP64_RS01775	COG1024	Enoyl-CoA hydratase
BKP64_RS01780	COG1960	acyl-CoA dehydrogenase activity
BKP64_RS01785	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BKP64_RS01800	COG1309	transcriptional regulator
BKP64_RS01820	COG3273	potassium ion transport
BKP64_RS01820	COG0471	metal ion transport
BKP64_RS01825	COG2199	diguanylate cyclase activity
BKP64_RS01825	COG2200	EAL domain
BKP64_RS01835	COG3038	cytochrome b561
BKP64_RS01840	COG2353	YceI-like domain
BKP64_RS01845	COG0840	transmembrane signaling receptor activity
BKP64_RS01860	COG0560	Phosphoserine phosphatase
BKP64_RS01860	COG3830	Belongs to the UPF0237 family
BKP64_RS01875	COG1509	lysine 2,3-aminomutase activity
BKP64_RS01880	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BKP64_RS01885	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
BKP64_RS01890	COG0688	phosphatidylethanolamine metabolic process
BKP64_RS01900	COG1360	Flagellar Motor Protein
BKP64_RS01905	COG1162	GTPase activity
BKP64_RS01910	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
BKP64_RS01920	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BKP64_RS01920	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BKP64_RS01925	COG0802	atpase or kinase
BKP64_RS01930	COG0860	N-Acetylmuramoyl-L-alanine amidase
BKP64_RS01940	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BKP64_RS01945	COG1923	regulation of RNA biosynthetic process
BKP64_RS01950	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BKP64_RS01955	COG0330	HflC and HflK could
BKP64_RS01960	COG0330	HflC and HflK could
BKP64_RS01965	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BKP64_RS01970	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BKP64_RS01975	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BKP64_RS01980	COG4106	trans-aconitate 2-methyltransferase activity
BKP64_RS01990	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BKP64_RS02000	COG1040	competence protein
BKP64_RS02005	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BKP64_RS02010	COG0156	8-amino-7-oxononanoate synthase activity
BKP64_RS02015	COG2226	methyltransferase
BKP64_RS02020	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BKP64_RS02035	COG1960	acyl-CoA dehydrogenase activity
BKP64_RS02040	COG1960	acyl-CoA dehydrogenase activity
BKP64_RS02055	COG1466	dna polymerase III delta subunit
BKP64_RS02065	COG0495	leucyl-tRNA aminoacylation
BKP64_RS02075	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BKP64_RS02080	COG4535	Mg2 and Co2 transporter CorC
BKP64_RS02085	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BKP64_RS02090	COG1702	phosphate starvation-inducible protein PhoH
BKP64_RS02095	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BKP64_RS02100	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BKP64_RS02115	COG0175	sulfate reduction
BKP64_RS02125	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BKP64_RS02130	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BKP64_RS02135	COG0154	amidase activity
BKP64_RS02140	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BKP64_RS02145	COG1077	Cell shape determining protein MreB Mrl
BKP64_RS02150	COG1792	Involved in formation and maintenance of cell shape
BKP64_RS02160	COG0424	maF-like protein
BKP64_RS02175	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BKP64_RS02180	COG3028	Belongs to the UPF0307 family
BKP64_RS02185	COG2239	Acts as a magnesium transporter
BKP64_RS02190	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BKP64_RS02195	COG1660	Displays ATPase and GTPase activities
BKP64_RS02215	COG1137	ATPase activity
BKP64_RS02240	COG1127	ABC transporter
BKP64_RS02245	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BKP64_RS02250	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BKP64_RS02265	COG5007	Belongs to the BolA IbaG family
BKP64_RS02270	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BKP64_RS02275	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BKP64_RS02290	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BKP64_RS02300	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BKP64_RS02305	COG0183	Belongs to the thiolase family
BKP64_RS02320	COG2197	response regulator
BKP64_RS02325	COG0204	Acyl-transferase
BKP64_RS02345	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
BKP64_RS02350	COG2205	protein histidine kinase activity
BKP64_RS02350	COG5002	protein histidine kinase activity
BKP64_RS02350	COG0784	Response regulator, receiver
BKP64_RS02355	COG1720	tRNA m6t6A37 methyltransferase activity
BKP64_RS02365	COG0237	dephospho-CoA kinase activity
BKP64_RS02385	COG4969	Belongs to the N-Me-Phe pilin family
BKP64_RS02395	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BKP64_RS02405	COG0250	Participates in transcription elongation, termination and antitermination
BKP64_RS02430	COG1086	Polysaccharide biosynthesis protein
BKP64_RS02435	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BKP64_RS02445	COG1028	Short-chain dehydrogenase reductase Sdr
BKP64_RS02460	COG2089	acid synthase
BKP64_RS02485	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BKP64_RS02505	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BKP64_RS02515	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BKP64_RS02525	COG3706	GGDEF domain
BKP64_RS02530	COG3437	response regulator, receiver
BKP64_RS02540	COG2925	Exonuclease
BKP64_RS02565	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BKP64_RS02575	COG0137	argininosuccinate synthase activity
BKP64_RS02585	COG0745	RESPONSE REGULATOR receiver
BKP64_RS02595	COG2211	Major facilitator Superfamily
BKP64_RS02610	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BKP64_RS02615	COG0459	protein refolding
BKP64_RS02635	COG0501	Belongs to the peptidase M48B family
BKP64_RS02640	COG1704	LemA family
BKP64_RS02645	COG2203	Gaf domain
BKP64_RS02645	COG5001	Diguanylate cyclase
BKP64_RS02645	COG4251	negative regulation of phosphorylation
BKP64_RS02645	COG3706	GGDEF domain
BKP64_RS02660	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BKP64_RS02695	COG1028	Short-chain dehydrogenase reductase Sdr
BKP64_RS02700	COG0183	Belongs to the thiolase family
BKP64_RS02710	COG0840	transmembrane signaling receptor activity
BKP64_RS02725	COG3706	GGDEF domain
BKP64_RS02735	COG0154	amidase activity
BKP64_RS02745	COG0729	surface antigen
BKP64_RS02750	COG2911	Protein conserved in bacteria
BKP64_RS02760	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BKP64_RS02770	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BKP64_RS02815	COG1677	Flagellar hook-basal body complex protein FliE
BKP64_RS02915	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BKP64_RS02945	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
BKP64_RS02950	COG2198	Histidine kinase
BKP64_RS02950	COG0784	Response regulator, receiver
BKP64_RS02950	COG0643	Histidine kinase
BKP64_RS02955	COG2201	protein-glutamate methylesterase activity
BKP64_RS02960	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BKP64_RS02970	COG1192	Involved in chromosome partitioning
BKP64_RS02980	COG0835	chemotaxis
BKP64_RS02990	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BKP64_RS02995	COG0714	Associated with various cellular activities
BKP64_RS03010	COG4133	protoheme IX ABC transporter activity
BKP64_RS03015	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BKP64_RS03030	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
BKP64_RS03065	COG2304	oxidoreductase activity
BKP64_RS03080	COG0714	Associated with various cellular activities
BKP64_RS03090	COG0288	reversible hydration of carbon dioxide
BKP64_RS03095	COG2813	Specifically methylates the guanine in position
BKP64_RS03100	COG2813	Specifically methylates the guanine in position
BKP64_RS03105	COG0307	riboflavin synthase, alpha
BKP64_RS03125	COG0668	transmembrane transport
BKP64_RS03140	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BKP64_RS03150	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BKP64_RS03155	COG1805	sodium ion transport
BKP64_RS03170	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BKP64_RS03175	COG2871	sodium ion transport
BKP64_RS03180	COG1477	protein flavinylation
BKP64_RS03190	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BKP64_RS03200	COG1605	Chorismate mutase
BKP64_RS03200	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BKP64_RS03210	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BKP64_RS03215	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BKP64_RS03230	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
BKP64_RS03235	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BKP64_RS03280	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BKP64_RS03290	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BKP64_RS03305	COG2350	Protein conserved in bacteria
BKP64_RS03310	COG0613	PHP domain protein
BKP64_RS03320	COG1530	ribonuclease E activity
BKP64_RS03330	COG0546	phosphoglycolate phosphatase activity
BKP64_RS03335	COG0616	signal peptide processing
BKP64_RS03350	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BKP64_RS03355	COG0416	fatty acid biosynthetic process
BKP64_RS03370	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BKP64_RS03375	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BKP64_RS03385	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BKP64_RS03425	COG0583	DNA-binding transcription factor activity
BKP64_RS03435	COG2133	pyrroloquinoline quinone binding
BKP64_RS03445	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BKP64_RS03450	COG3047	cAMP biosynthetic process
BKP64_RS03460	COG1136	(ABC) transporter
BKP64_RS03460	COG0577	efflux transmembrane transporter activity
BKP64_RS03465	COG0577	efflux transmembrane transporter activity
BKP64_RS03465	COG1136	(ABC) transporter
BKP64_RS03475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BKP64_RS03480	COG4597	amino acid ABC transporter
BKP64_RS03485	COG0765	amino acid transport
BKP64_RS03490	COG1126	abc transporter atp-binding protein
BKP64_RS03495	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BKP64_RS03500	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BKP64_RS03505	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BKP64_RS03510	COG0215	cysteine-tRNA ligase activity
BKP64_RS03515	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BKP64_RS03520	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BKP64_RS03545	COG0544	peptidyl-prolyl cis-trans isomerase activity
BKP64_RS03550	COG0740	serine-type endopeptidase activity
BKP64_RS03555	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BKP64_RS03560	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BKP64_RS03570	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BKP64_RS03590	COG0800	Aldolase
BKP64_RS03610	COG0837	glucose binding
BKP64_RS03615	COG0778	Nitroreductase
BKP64_RS03620	COG1573	uracil-dna glycosylase
BKP64_RS03625	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BKP64_RS03630	COG1349	DNA-binding transcription factor activity
BKP64_RS03640	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BKP64_RS03640	COG2169	Transcriptional regulator
BKP64_RS03645	COG1477	protein flavinylation
BKP64_RS03680	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BKP64_RS03740	COG3300	MHYT domain
BKP64_RS03740	COG5001	Diguanylate cyclase
BKP64_RS03745	COG3243	poly(R)-hydroxyalkanoic acid synthase
BKP64_RS03760	COG1136	(ABC) transporter
BKP64_RS03780	COG3647	Membrane
BKP64_RS03785	COG0471	metal ion transport
BKP64_RS03820	COG1309	transcriptional regulator
BKP64_RS03825	COG0037	tRNA processing
BKP64_RS03840	COG2217	Heavy metal translocating P-type atpase
BKP64_RS03850	COG0348	domain, Protein
BKP64_RS03855	COG2010	Cytochrome c
BKP64_RS03870	COG3278	Belongs to the heme-copper respiratory oxidase family
BKP64_RS03880	COG3706	GGDEF domain
BKP64_RS03885	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
BKP64_RS03905	COG3101	peptidyl-lysine hydroxylation
BKP64_RS03910	COG0513	Belongs to the DEAD box helicase family
BKP64_RS03915	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BKP64_RS03920	COG0501	Belongs to the peptidase M48B family
BKP64_RS03930	COG0436	Aminotransferase
BKP64_RS03935	COG0386	Belongs to the glutathione peroxidase family
BKP64_RS03940	COG1846	Transcriptional regulator
BKP64_RS03945	COG0784	Response regulator, receiver
BKP64_RS03945	COG5002	protein histidine kinase activity
BKP64_RS03945	COG2205	protein histidine kinase activity
BKP64_RS03965	COG2850	peptidyl-arginine hydroxylation
BKP64_RS03975	COG2915	High frequency lysogenization protein hflD homolog
BKP64_RS03980	COG0482	sulfurtransferase activity
BKP64_RS03995	COG1278	Cold shock
BKP64_RS04000	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BKP64_RS04005	COG0542	response to heat
BKP64_RS04010	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BKP64_RS04015	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
BKP64_RS04020	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
BKP64_RS04025	COG0492	ferredoxin-NADP+ reductase activity
BKP64_RS04030	COG0714	Associated with various cellular activities
BKP64_RS04035	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BKP64_RS04040	COG2957	Belongs to the agmatine deiminase family
BKP64_RS04060	COG1136	(ABC) transporter
BKP64_RS04075	COG0811	peptide transport
BKP64_RS04080	COG0848	biopolymer transport protein
BKP64_RS04085	COG1132	(ABC) transporter
BKP64_RS04090	COG1663	tetraacyldisaccharide 4'-kinase activity
BKP64_RS04095	COG2835	tetraacyldisaccharide 4'-kinase activity
BKP64_RS04100	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
BKP64_RS04105	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BKP64_RS04115	COG0442	prolyl-tRNA aminoacylation
BKP64_RS04125	COG1522	sequence-specific DNA binding
BKP64_RS04130	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BKP64_RS04135	COG1278	Cold shock
BKP64_RS04145	COG1570	exodeoxyribonuclease VII activity
BKP64_RS04155	COG0519	Catalyzes the synthesis of GMP from XMP
BKP64_RS04155	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BKP64_RS04160	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BKP64_RS04165	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BKP64_RS04180	COG1752	Esterase of the alpha-beta hydrolase superfamily
BKP64_RS04185	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BKP64_RS04190	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BKP64_RS04195	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BKP64_RS04195	COG0574	Belongs to the PEP-utilizing enzyme family
BKP64_RS04205	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BKP64_RS04205	COG1796	DNA polymerase
BKP64_RS04230	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BKP64_RS04240	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BKP64_RS04255	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BKP64_RS04260	COG0438	transferase activity, transferring glycosyl groups
BKP64_RS04295	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BKP64_RS04300	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BKP64_RS04305	COG0632	four-way junction helicase activity
BKP64_RS04310	COG2255	four-way junction helicase activity
BKP64_RS04315	COG0824	Thioesterase
BKP64_RS04335	COG0823	Involved in the tonB-independent uptake of proteins
BKP64_RS04360	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BKP64_RS04365	COG4783	chaperone-mediated protein folding
BKP64_RS04370	COG0425	Belongs to the sulfur carrier protein TusA family
BKP64_RS04380	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BKP64_RS04385	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BKP64_RS04395	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BKP64_RS04410	COG0564	pseudouridine synthase activity
BKP64_RS04430	COG0697	spore germination
BKP64_RS04455	COG0438	transferase activity, transferring glycosyl groups
BKP64_RS04465	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BKP64_RS04465	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BKP64_RS04485	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BKP64_RS04490	COG0372	Belongs to the citrate synthase family
BKP64_RS04495	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BKP64_RS04505	COG2079	MmgE PrpD family protein
BKP64_RS04510	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BKP64_RS04515	COG3409	Peptidoglycan-binding domain 1 protein
BKP64_RS04515	COG3267	Type II secretory pathway component ExeA
BKP64_RS04525	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BKP64_RS04580	COG0438	transferase activity, transferring glycosyl groups
BKP64_RS04585	COG0367	asparagine synthase
BKP64_RS04595	COG0438	transferase activity, transferring glycosyl groups
BKP64_RS04610	COG0438	transferase activity, transferring glycosyl groups
BKP64_RS04615	COG1215	transferase activity, transferring glycosyl groups
BKP64_RS04620	COG1216	Glycosyl transferase, family 2
BKP64_RS04635	COG1215	transferase activity, transferring glycosyl groups
BKP64_RS04660	COG2244	polysaccharide biosynthetic process
BKP64_RS04685	COG2204	response regulator
BKP64_RS04690	COG4191	Histidine kinase
BKP64_RS04700	COG0204	Acyl-transferase
BKP64_RS04705	COG0676	glucose-6-phosphate 1-epimerase activity
BKP64_RS04720	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BKP64_RS04725	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BKP64_RS04730	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BKP64_RS04740	COG3100	YcgL domain-containing protein
BKP64_RS04745	COG2983	Belongs to the UPF0260 family
BKP64_RS04760	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BKP64_RS04820	COG2030	dehydratase
BKP64_RS04825	COG0318	PFAM AMP-dependent synthetase and ligase
BKP64_RS04830	COG1643	Atp-dependent helicase
BKP64_RS04845	COG2853	Lipoprotein
BKP64_RS04850	COG1752	Esterase of the alpha-beta hydrolase superfamily
BKP64_RS04855	COG3409	Peptidoglycan-binding domain 1 protein
BKP64_RS04855	COG3267	Type II secretory pathway component ExeA
BKP64_RS04865	COG1199	ATP-dependent helicase activity
BKP64_RS04930	COG0596	Alpha beta hydrolase
BKP64_RS04950	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BKP64_RS04970	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BKP64_RS04975	COG0066	3-isopropylmalate dehydratase activity
BKP64_RS04980	COG0473	3-isopropylmalate dehydrogenase activity
BKP64_RS04995	COG0101	tRNA pseudouridine synthase activity
BKP64_RS05000	COG0135	phosphoribosylanthranilate isomerase activity
BKP64_RS05010	COG0159	tryptophan synthase activity
BKP64_RS05015	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BKP64_RS05020	COG0285	dihydrofolate synthase activity
BKP64_RS05030	COG1286	toxin biosynthetic process
BKP64_RS05050	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BKP64_RS05055	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BKP64_RS05060	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BKP64_RS05065	COG1648	precorrin-2 dehydrogenase activity
BKP64_RS05065	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BKP64_RS05070	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BKP64_RS05090	COG4172	Belongs to the ABC transporter superfamily
BKP64_RS05095	COG4239	(ABC) transporter, permease
BKP64_RS05100	COG4174	ABC transporter (Permease)
BKP64_RS05105	COG4166	transmembrane transport
BKP64_RS05115	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BKP64_RS05125	COG0328	RNA-DNA hybrid ribonuclease activity
BKP64_RS05130	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BKP64_RS05150	COG0616	signal peptide processing
BKP64_RS05155	COG0604	alcohol dehydrogenase
BKP64_RS05165	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BKP64_RS05180	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BKP64_RS05180	COG0316	Belongs to the HesB IscA family
BKP64_RS05195	COG2920	part of a sulfur-relay system
BKP64_RS05215	COG0670	Belongs to the BI1 family
BKP64_RS05235	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BKP64_RS05240	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BKP64_RS05240	COG3453	Protein conserved in bacteria
BKP64_RS05260	COG1309	transcriptional regulator
BKP64_RS05280	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BKP64_RS05295	COG4221	oxidoreductase activity
BKP64_RS05310	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
BKP64_RS05330	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BKP64_RS05340	COG2205	protein histidine kinase activity
BKP64_RS05345	COG3437	response regulator, receiver
BKP64_RS05360	COG2200	EAL domain
BKP64_RS05360	COG2202	Pas domain
BKP64_RS05360	COG2199	diguanylate cyclase activity
BKP64_RS05400	COG2226	methyltransferase
BKP64_RS05440	COG3268	Saccharopine dehydrogenase
BKP64_RS05445	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BKP64_RS05450	COG4988	ABC transporter
BKP64_RS05455	COG1294	oxidase, subunit
BKP64_RS05460	COG1271	oxidase subunit
BKP64_RS05465	COG2226	methyltransferase
BKP64_RS05480	COG1752	Esterase of the alpha-beta hydrolase superfamily
BKP64_RS05485	COG1024	Enoyl-CoA hydratase
BKP64_RS05495	COG0842	Transport permease protein
BKP64_RS05500	COG1131	(ABC) transporter
BKP64_RS05515	COG3639	organic phosphonate transmembrane transporter activity
BKP64_RS05520	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BKP64_RS05525	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
BKP64_RS05535	COG0709	Synthesizes selenophosphate from selenide and ATP
BKP64_RS05550	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BKP64_RS05550	COG3153	acetyltransferase
BKP64_RS05570	COG0514	ATP-dependent DNA helicase (RecQ)
BKP64_RS05590	COG0297	glycogen (starch) synthase activity
BKP64_RS05595	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BKP64_RS05600	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BKP64_RS05635	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
BKP64_RS05640	COG4067	protein conserved in archaea
BKP64_RS05640	COG0189	ligase activity
BKP64_RS05695	COG0732	type I restriction modification DNA specificity domain
BKP64_RS05705	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
BKP64_RS05780	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BKP64_RS05795	COG0583	DNA-binding transcription factor activity
BKP64_RS05805	COG1984	allophanate hydrolase subunit 2
BKP64_RS05815	COG0439	Biotin carboxylase
BKP64_RS05825	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BKP64_RS05830	COG1172	Belongs to the binding-protein-dependent transport system permease family
BKP64_RS05835	COG1129	ABC transporter
BKP64_RS05840	COG1879	ABC-type sugar transport system periplasmic component
BKP64_RS05860	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BKP64_RS05870	COG0579	oxidoreductase
BKP64_RS05890	COG0577	efflux transmembrane transporter activity
BKP64_RS05890	COG1136	(ABC) transporter
BKP64_RS05895	COG1136	(ABC) transporter
BKP64_RS05935	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BKP64_RS05940	COG0022	dehydrogenase e1 component
BKP64_RS05950	COG0515	serine threonine protein kinase
BKP64_RS06010	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BKP64_RS06035	COG0737	Belongs to the 5'-nucleotidase family
BKP64_RS06045	COG3258	Cytochrome c
BKP64_RS06085	COG3002	Belongs to the UPF0753 family
BKP64_RS06090	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BKP64_RS06095	COG0583	DNA-binding transcription factor activity
BKP64_RS06105	COG1522	sequence-specific DNA binding
BKP64_RS06110	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BKP64_RS06120	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BKP64_RS06220	COG0277	FAD linked oxidase domain protein
BKP64_RS06225	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BKP64_RS06230	COG1070	Carbohydrate kinase
BKP64_RS06240	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BKP64_RS06270	COG0300	oxidoreductase activity
BKP64_RS06280	COG2226	methyltransferase
BKP64_RS06285	COG1061	Type III restriction enzyme res subunit
BKP64_RS06305	COG3383	formate dehydrogenase (NAD+) activity
BKP64_RS06390	COG0328	RNA-DNA hybrid ribonuclease activity
BKP64_RS06400	COG4974	Belongs to the 'phage' integrase family
BKP64_RS06420	COG4143	(ABC) transporter
BKP64_RS06425	COG1178	ABC-type Fe3 transport system permease component
BKP64_RS06430	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
BKP64_RS06435	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BKP64_RS06475	COG0840	transmembrane signaling receptor activity
BKP64_RS06480	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BKP64_RS06490	COG0251	oxidation-reduction process
BKP64_RS06510	COG0765	amino acid transport
BKP64_RS06515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BKP64_RS06520	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BKP64_RS06525	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BKP64_RS06530	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BKP64_RS06535	COG0583	DNA-binding transcription factor activity
BKP64_RS06545	COG3001	Fructosamine kinase
BKP64_RS06550	COG1254	Belongs to the acylphosphatase family
BKP64_RS06590	COG0583	DNA-binding transcription factor activity
BKP64_RS06595	COG2814	Major facilitator Superfamily
BKP64_RS06600	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BKP64_RS06605	COG0784	Response regulator, receiver
BKP64_RS06605	COG0835	chemotaxis
BKP64_RS06615	COG2747	anti-sigma28 factor FlgM
BKP64_RS06635	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
BKP64_RS06635	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BKP64_RS06650	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BKP64_RS06655	COG3115	cell septum assembly
BKP64_RS06665	COG2186	Transcriptional regulator
BKP64_RS06680	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BKP64_RS06690	COG0180	Tryptophanyl-tRNA synthetase
BKP64_RS06700	COG0045	succinate-CoA ligase (ADP-forming) activity
BKP64_RS06725	COG1053	succinate dehydrogenase
BKP64_RS06730	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BKP64_RS06750	COG2084	Dehydrogenase
BKP64_RS06760	COG0183	Belongs to the thiolase family
BKP64_RS06765	COG1024	Enoyl-CoA hydratase
BKP64_RS06765	COG1250	3-hydroxyacyl-CoA dehydrogenase
BKP64_RS06780	COG0589	response to stress
BKP64_RS06790	COG0488	(ABC) transporter
BKP64_RS06795	COG0633	Ferredoxin
BKP64_RS06795	COG3217	Mosc domain protein beta barrel domain protein
BKP64_RS06820	COG1090	epimerase
BKP64_RS06845	COG1160	GTP binding
BKP64_RS06850	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BKP64_RS06855	COG2976	Protein conserved in bacteria
BKP64_RS06860	COG0124	histidyl-tRNA synthetase
BKP64_RS06865	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BKP64_RS06870	COG1426	Protein conserved in bacteria
BKP64_RS06880	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BKP64_RS06885	COG0105	UTP biosynthetic process
BKP64_RS06905	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
BKP64_RS06915	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BKP64_RS06925	COG1862	Preprotein translocase
BKP64_RS06930	COG0343	queuine tRNA-ribosyltransferase activity
BKP64_RS06935	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BKP64_RS06960	COG1706	bacterial-type flagellum-dependent cell motility
BKP64_RS06965	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
BKP64_RS06970	COG4786	Flagellar basal body rod
BKP64_RS06975	COG4787	bacterial-type flagellum-dependent cell motility
BKP64_RS06980	COG1749	Flagellar hook protein flgE
BKP64_RS06985	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BKP64_RS06990	COG1558	bacterial-type flagellum-dependent cell motility
BKP64_RS06995	COG1815	bacterial-type flagellum-dependent cell motility
BKP64_RS07015	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BKP64_RS07015	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BKP64_RS07020	COG0842	Transport permease protein
BKP64_RS07025	COG1131	(ABC) transporter
BKP64_RS07050	COG1840	ABC-type Fe3 transport system, periplasmic component
BKP64_RS07065	COG1022	Amp-dependent synthetase and ligase
BKP64_RS07075	COG4120	Belongs to the binding-protein-dependent transport system permease family
BKP64_RS07080	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
BKP64_RS07125	COG4572	Cation transport regulator
BKP64_RS07145	COG1607	acyl-coa hydrolase
BKP64_RS07150	COG1162	GTPase activity
BKP64_RS07165	COG0251	oxidation-reduction process
BKP64_RS07190	COG4603	Belongs to the binding-protein-dependent transport system permease family
BKP64_RS07200	COG0410	ABC transporter
BKP64_RS07210	COG1136	(ABC) transporter
BKP64_RS07220	COG0583	DNA-binding transcription factor activity
BKP64_RS07240	COG1794	racemase activity, acting on amino acids and derivatives
BKP64_RS07250	COG3588	fructose-bisphosphate aldolase
BKP64_RS07255	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BKP64_RS07260	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BKP64_RS07265	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
BKP64_RS07275	COG0326	Molecular chaperone. Has ATPase activity
BKP64_RS07315	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
BKP64_RS07320	COG4181	ATPase activity
BKP64_RS07340	COG1362	aminopeptidase activity
BKP64_RS07355	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BKP64_RS07355	COG0116	Belongs to the methyltransferase superfamily
BKP64_RS07360	COG3130	regulation of translation
BKP64_RS07365	COG0167	dihydroorotate dehydrogenase activity
BKP64_RS07390	COG0436	Aminotransferase
BKP64_RS07400	COG0284	orotidine-5'-phosphate decarboxylase activity
BKP64_RS07405	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BKP64_RS07415	COG0776	regulation of translation
BKP64_RS07425	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BKP64_RS07430	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BKP64_RS07440	COG1605	Chorismate mutase
BKP64_RS07440	COG0077	Prephenate dehydratase
BKP64_RS07455	COG0788	formyltetrahydrofolate deformylase activity
BKP64_RS07460	COG0405	Gamma-glutamyltransferase
BKP64_RS07470	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BKP64_RS07485	COG1067	ATP-dependent peptidase activity
BKP64_RS07495	COG0625	glutathione transferase activity
BKP64_RS07520	COG0366	Alpha amylase catalytic
BKP64_RS07605	COG2161	toxin-antitoxin pair type II binding
BKP64_RS07630	COG3093	addiction module antidote protein HigA
BKP64_RS07695	COG3344	reverse transcriptase
BKP64_RS07705	COG2161	toxin-antitoxin pair type II binding
BKP64_RS07710	COG4115	mRNA cleavage
BKP64_RS07725	COG2154	pterin-4-alpha-carbinolamine dehydratase
BKP64_RS07730	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BKP64_RS07740	COG0587	DNA-directed DNA polymerase activity
BKP64_RS07745	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
BKP64_RS07755	COG3630	sodium ion export across plasma membrane
BKP64_RS07760	COG0513	Belongs to the DEAD box helicase family
BKP64_RS07765	COG3122	Protein conserved in bacteria
BKP64_RS07780	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BKP64_RS07810	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BKP64_RS07820	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BKP64_RS07855	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BKP64_RS07865	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BKP64_RS07875	COG0795	lipopolysaccharide-transporting ATPase activity
BKP64_RS07880	COG0795	lipopolysaccharide-transporting ATPase activity
BKP64_RS07885	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BKP64_RS07905	COG2096	Adenosyltransferase
BKP64_RS07920	COG3023	N-Acetylmuramoyl-L-alanine amidase
BKP64_RS07940	COG1192	Involved in chromosome partitioning
BKP64_RS07945	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BKP64_RS07950	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BKP64_RS07960	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BKP64_RS07965	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BKP64_RS07975	COG3977	Valine--pyruvate aminotransferase
BKP64_RS07985	COG0717	Belongs to the dCTP deaminase family
BKP64_RS07990	COG0489	protein tyrosine kinase activity
BKP64_RS07995	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BKP64_RS07995	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BKP64_RS08000	COG4657	Part of a membrane complex involved in electron transport
BKP64_RS08005	COG2878	Part of a membrane complex involved in electron transport
BKP64_RS08010	COG4656	Part of a membrane complex involved in electron transport
BKP64_RS08015	COG4658	electron transport chain
BKP64_RS08025	COG4660	Part of a membrane complex involved in electron transport
BKP64_RS08030	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BKP64_RS08055	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BKP64_RS08060	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BKP64_RS08065	COG0585	pseudouridine synthase activity
BKP64_RS08070	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BKP64_RS08075	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BKP64_RS08080	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BKP64_RS08085	COG0148	phosphopyruvate hydratase activity
BKP64_RS08090	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BKP64_RS08095	COG0504	CTP synthase activity
BKP64_RS08100	COG0037	tRNA processing
BKP64_RS08105	COG0825	malonyl-CoA metabolic process
BKP64_RS08115	COG0587	DNA-directed DNA polymerase activity
BKP64_RS08120	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BKP64_RS08125	COG1393	Belongs to the ArsC family
BKP64_RS08140	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BKP64_RS08150	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
BKP64_RS08155	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
BKP64_RS08160	COG0235	Class ii aldolase
BKP64_RS08180	COG2840	Smr protein MutS2
BKP64_RS08185	COG2239	Acts as a magnesium transporter
BKP64_RS08190	COG2176	DNA-directed DNA polymerase activity
BKP64_RS08200	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BKP64_RS08210	COG0784	Response regulator, receiver
BKP64_RS08210	COG2205	protein histidine kinase activity
BKP64_RS08250	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BKP64_RS08270	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BKP64_RS08275	COG0047	phosphoribosylformylglycinamidine synthase activity
BKP64_RS08275	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BKP64_RS08280	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
BKP64_RS08285	COG2137	regulation of response to DNA damage stimulus
BKP64_RS08300	COG0183	Belongs to the thiolase family
BKP64_RS08305	COG1250	3-hydroxyacyl-CoA dehydrogenase
BKP64_RS08305	COG1024	Enoyl-CoA hydratase
BKP64_RS08320	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BKP64_RS08325	COG0402	S-adenosylhomocysteine deaminase activity
BKP64_RS08330	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BKP64_RS08340	COG1028	Short-chain dehydrogenase reductase Sdr
BKP64_RS08350	COG3022	response to hydroperoxide
BKP64_RS08360	COG2974	May be involved in recombination
BKP64_RS08365	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BKP64_RS08365	COG0045	succinate-CoA ligase (ADP-forming) activity
BKP64_RS08365	COG1042	CoA-binding domain protein
BKP64_RS08370	COG0123	including yeast histone deacetylase and acetoin utilization protein
BKP64_RS08380	COG0418	dihydroorotase activity
BKP64_RS08385	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BKP64_RS08390	COG4221	oxidoreductase activity
BKP64_RS08445	COG2132	Multicopper oxidase
BKP64_RS08480	COG0009	L-threonylcarbamoyladenylate synthase
BKP64_RS08485	COG0271	Belongs to the BolA IbaG family
BKP64_RS08495	COG0745	RESPONSE REGULATOR receiver
BKP64_RS08505	COG5002	protein histidine kinase activity
BKP64_RS08520	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BKP64_RS08525	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BKP64_RS08530	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BKP64_RS08535	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BKP64_RS08540	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BKP64_RS08560	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BKP64_RS08570	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BKP64_RS08575	COG0233	cytoplasmic translational termination
BKP64_RS08580	COG0528	UMP kinase activity
BKP64_RS08585	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BKP64_RS08590	COG0052	Belongs to the universal ribosomal protein uS2 family
BKP64_RS08605	COG0436	Aminotransferase
BKP64_RS08610	COG1393	Belongs to the ArsC family
BKP64_RS08615	COG2171	N-acyltransferase activity
BKP64_RS08620	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BKP64_RS08625	COG2900	Belongs to the SlyX family
BKP64_RS08630	COG1278	Cold shock
BKP64_RS08655	COG2130	NADP-dependent
BKP64_RS08660	COG0604	alcohol dehydrogenase
BKP64_RS08660	COG3321	synthase
BKP64_RS08660	COG1028	Short-chain dehydrogenase reductase Sdr
BKP64_RS08670	COG0366	Alpha amylase catalytic
BKP64_RS08675	COG1215	transferase activity, transferring glycosyl groups
BKP64_RS08680	COG3769	mannosylglycerate metabolic process
BKP64_RS08690	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BKP64_RS08695	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
BKP64_RS08695	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
BKP64_RS08700	COG2267	carboxylic ester hydrolase activity
BKP64_RS08705	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BKP64_RS08710	COG2207	Transcriptional regulator
BKP64_RS08720	COG1322	Protein conserved in bacteria
BKP64_RS08730	COG4067	protein conserved in archaea
BKP64_RS08730	COG0189	ligase activity
BKP64_RS08740	COG0189	ligase activity
BKP64_RS08745	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BKP64_RS08750	COG0069	glutamate synthase activity
BKP64_RS08780	COG2197	response regulator
BKP64_RS08815	COG0776	regulation of translation
BKP64_RS08820	COG0072	phenylalanine-tRNA ligase activity
BKP64_RS08820	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BKP64_RS08825	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BKP64_RS08830	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BKP64_RS08835	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BKP64_RS08840	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BKP64_RS08845	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BKP64_RS08855	COG2358	TRAP transporter, solute receptor (TAXI family
BKP64_RS08860	COG2409	Drug exporters of the RND superfamily
BKP64_RS08875	COG0308	aminopeptidase N
BKP64_RS08890	COG0705	Rhomboid family
BKP64_RS08895	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BKP64_RS08900	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BKP64_RS08910	COG1902	pentaerythritol trinitrate reductase activity
BKP64_RS08910	COG0446	pyridine nucleotide-disulphide oxidoreductase
BKP64_RS08925	COG4753	response regulator
BKP64_RS08925	COG2207	Transcriptional regulator
BKP64_RS08940	COG4566	intracellular signal transduction
BKP64_RS08945	COG1067	ATP-dependent peptidase activity
BKP64_RS08960	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BKP64_RS08965	COG1546	Belongs to the CinA family
BKP64_RS09005	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BKP64_RS09015	COG1280	lysine exporter protein (LysE YggA)
BKP64_RS09025	COG1307	EDD domain protein, DegV family
BKP64_RS09035	COG0318	PFAM AMP-dependent synthetase and ligase
BKP64_RS09040	COG4191	Histidine kinase
BKP64_RS09045	COG4566	intracellular signal transduction
BKP64_RS09050	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BKP64_RS09060	COG1064	alcohol dehydrogenase
BKP64_RS09065	COG2081	HI0933 family
BKP64_RS09070	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BKP64_RS09075	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BKP64_RS09080	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
BKP64_RS09085	COG3639	organic phosphonate transmembrane transporter activity
BKP64_RS09090	COG2188	Transcriptional regulator
BKP64_RS09095	COG3624	Phosphonate C-P lyase system protein PhnG
BKP64_RS09100	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
BKP64_RS09105	COG3626	phosphonate metabolism
BKP64_RS09110	COG3627	carbon phosphorus lyase activity
BKP64_RS09115	COG4107	phosphonate C-P lyase system protein PhnK
BKP64_RS09120	COG4778	phosphonate C-P lyase system protein PhnL
BKP64_RS09125	COG3454	Phosphonate metabolism
BKP64_RS09140	COG0318	PFAM AMP-dependent synthetase and ligase
BKP64_RS09160	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BKP64_RS09165	COG1802	Transcriptional regulator
BKP64_RS09170	COG0589	response to stress
BKP64_RS09175	COG0659	secondary active sulfate transmembrane transporter activity
BKP64_RS09185	COG3145	DNA-N1-methyladenine dioxygenase activity
BKP64_RS09190	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BKP64_RS09195	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BKP64_RS09205	COG5001	Diguanylate cyclase
BKP64_RS09205	COG4251	negative regulation of phosphorylation
BKP64_RS09205	COG3706	GGDEF domain
BKP64_RS09205	COG2203	Gaf domain
BKP64_RS09235	COG0183	Belongs to the thiolase family
BKP64_RS09240	COG1960	acyl-CoA dehydrogenase activity
BKP64_RS09255	COG1960	acyl-CoA dehydrogenase activity
BKP64_RS09260	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BKP64_RS09270	COG4770	biotin carboxylase activity
BKP64_RS09285	COG0318	PFAM AMP-dependent synthetase and ligase
BKP64_RS09305	COG2175	clavaminate synthase activity
BKP64_RS09400	COG1704	LemA family
BKP64_RS09405	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
BKP64_RS09415	COG2897	thiosulfate sulfurtransferase activity
BKP64_RS09430	COG3344	reverse transcriptase
BKP64_RS09450	COG0028	Belongs to the TPP enzyme family
BKP64_RS09475	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BKP64_RS09480	COG1012	belongs to the aldehyde dehydrogenase family
BKP64_RS09485	COG0174	glutamine synthetase
BKP64_RS09490	COG2863	cytochrome
BKP64_RS09495	COG3258	Cytochrome c
BKP64_RS09500	COG0842	Transport permease protein
BKP64_RS09505	COG0842	Transport permease protein
BKP64_RS09510	COG1131	(ABC) transporter
BKP64_RS09515	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BKP64_RS09560	COG3938	Belongs to the proline racemase family
BKP64_RS09575	COG0765	amino acid transport
BKP64_RS09580	COG0765	amino acid transport
BKP64_RS09585	COG1126	abc transporter atp-binding protein
BKP64_RS09590	COG5001	Diguanylate cyclase
BKP64_RS09590	COG4251	negative regulation of phosphorylation
BKP64_RS09590	COG3706	GGDEF domain
BKP64_RS09590	COG2203	Gaf domain
BKP64_RS09600	COG1410	methionine synthase
BKP64_RS09600	COG0646	methionine synthase
BKP64_RS09620	COG1024	Enoyl-CoA hydratase
BKP64_RS09625	COG1960	acyl-CoA dehydrogenase activity
BKP64_RS09655	COG0217	transcriptional regulatory protein
BKP64_RS09660	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BKP64_RS09660	COG0519	Catalyzes the synthesis of GMP from XMP
BKP64_RS09670	COG0631	protein serine/threonine phosphatase activity
BKP64_RS09675	COG2815	serine threonine protein kinase
BKP64_RS09675	COG0515	serine threonine protein kinase
BKP64_RS09700	COG0523	cobalamin synthesis protein
BKP64_RS09705	COG0390	transport system, permease component
BKP64_RS09710	COG1136	(ABC) transporter
BKP64_RS09720	COG1187	pseudouridine synthase activity
BKP64_RS09725	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BKP64_RS09735	COG4221	oxidoreductase activity
BKP64_RS09755	COG2135	peptidase activity
BKP64_RS09775	COG0791	NLP P60 protein
BKP64_RS09785	COG0583	DNA-binding transcription factor activity
BKP64_RS09800	COG1024	Enoyl-CoA hydratase
BKP64_RS09800	COG1250	3-hydroxyacyl-CoA dehydrogenase
BKP64_RS09815	COG1234	tRNA 3'-trailer cleavage
BKP64_RS09820	COG1278	Cold shock
BKP64_RS09840	COG0733	neurotransmitter:sodium symporter activity
BKP64_RS09875	COG3228	Belongs to the MtfA family
BKP64_RS09880	COG1944	ATP diphosphatase activity
BKP64_RS09885	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
BKP64_RS09905	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
BKP64_RS09915	COG1280	lysine exporter protein (LysE YggA)
BKP64_RS09940	COG2824	Alkylphosphonate utilization operon protein PhnA
BKP64_RS09950	COG1671	Belongs to the UPF0178 family
BKP64_RS09955	COG1132	(ABC) transporter
BKP64_RS09960	COG1120	ATPase activity
BKP64_RS09965	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BKP64_RS09970	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BKP64_RS09980	COG4773	Receptor
BKP64_RS09990	COG0656	L-ascorbic acid biosynthetic process
BKP64_RS10030	COG1028	Short-chain dehydrogenase reductase Sdr
BKP64_RS10080	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BKP64_RS10105	COG0277	FAD linked oxidase domain protein
BKP64_RS10105	COG0247	lactate metabolic process
BKP64_RS10115	COG2200	EAL domain
BKP64_RS10120	COG0473	3-isopropylmalate dehydrogenase activity
BKP64_RS10135	COG0436	Aminotransferase
BKP64_RS10150	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BKP64_RS10185	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BKP64_RS10190	COG2816	NAD+ diphosphatase activity
BKP64_RS10195	COG2937	Belongs to the GPAT DAPAT family
BKP64_RS10200	COG0742	ribosomal rna small subunit methyltransferase
BKP64_RS10210	COG1214	PFAM Peptidase M22, glycoprotease
BKP64_RS10215	COG0563	adenylate kinase activity
BKP64_RS10225	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BKP64_RS10240	COG3956	TIGRFAM MazG family protein
BKP64_RS10245	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BKP64_RS10250	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BKP64_RS10260	COG2205	protein histidine kinase activity
BKP64_RS10260	COG5002	protein histidine kinase activity
BKP64_RS10260	COG0784	Response regulator, receiver
BKP64_RS10270	COG1381	Involved in DNA repair and RecF pathway recombination
BKP64_RS10275	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BKP64_RS10280	COG0571	ribonuclease III activity
BKP64_RS10290	COG0681	Belongs to the peptidase S26 family
BKP64_RS10295	COG0481	GTPase activity
BKP64_RS10305	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BKP64_RS10355	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BKP64_RS10360	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BKP64_RS10365	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BKP64_RS10395	COG0335	large ribosomal subunit rRNA binding
BKP64_RS10400	COG0336	Belongs to the RNA methyltransferase TrmD family
BKP64_RS10405	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BKP64_RS10410	COG0228	four-way junction DNA binding
BKP64_RS10415	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BKP64_RS10425	COG4536	flavin adenine dinucleotide binding
BKP64_RS10445	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BKP64_RS10450	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BKP64_RS10455	COG3842	ATPase activity
BKP64_RS10460	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BKP64_RS10465	COG2205	protein histidine kinase activity
BKP64_RS10470	COG0745	RESPONSE REGULATOR receiver
BKP64_RS10485	COG1047	Peptidyl-prolyl cis-trans
BKP64_RS10490	COG0427	acetyl-CoA hydrolase
BKP64_RS10500	COG0667	Aldo Keto reductase
BKP64_RS10515	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BKP64_RS10530	COG0850	regulation of cytokinetic process
BKP64_RS10535	COG2894	cell division
BKP64_RS10540	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
BKP64_RS10560	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BKP64_RS10595	COG4191	Histidine kinase
BKP64_RS10620	COG0189	ligase activity
BKP64_RS10625	COG4067	protein conserved in archaea
BKP64_RS10625	COG0189	ligase activity
BKP64_RS10645	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BKP64_RS10655	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BKP64_RS10660	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BKP64_RS10670	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
BKP64_RS10675	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BKP64_RS10685	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BKP64_RS10690	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BKP64_RS10695	COG0193	aminoacyl-tRNA hydrolase activity
BKP64_RS10860	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
BKP64_RS10870	COG1846	Transcriptional regulator
BKP64_RS10930	COG4626	Terminase
BKP64_RS10930	COG1802	Transcriptional regulator
BKP64_RS11095	COG4974	Belongs to the 'phage' integrase family
BKP64_RS11130	COG2873	o-acetylhomoserine
BKP64_RS11135	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BKP64_RS11140	COG0840	transmembrane signaling receptor activity
BKP64_RS11155	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BKP64_RS11165	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BKP64_RS11180	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BKP64_RS11185	COG0305	Participates in initiation and elongation during chromosome replication
BKP64_RS11190	COG0359	binds to the 23S rRNA
BKP64_RS11200	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BKP64_RS11205	COG0360	Binds together with S18 to 16S ribosomal RNA
BKP64_RS11210	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BKP64_RS11215	COG0557	exoribonuclease II activity
BKP64_RS11260	COG1960	acyl-CoA dehydrogenase activity
BKP64_RS11270	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BKP64_RS11275	COG0205	6-phosphofructokinase activity
BKP64_RS11290	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BKP64_RS11295	COG0321	lipoyl(octanoyl) transferase activity
BKP64_RS11300	COG2921	Belongs to the UPF0250 family
BKP64_RS11305	COG1686	Belongs to the peptidase S11 family
BKP64_RS11315	COG0772	Belongs to the SEDS family
BKP64_RS11320	COG0768	penicillin binding
BKP64_RS11325	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BKP64_RS11335	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BKP64_RS11340	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BKP64_RS11355	COG0586	Pfam SNARE associated Golgi protein
BKP64_RS11370	COG0129	dihydroxy-acid dehydratase activity
BKP64_RS11380	COG0628	permease
BKP64_RS11390	COG0596	Alpha beta hydrolase
BKP64_RS11410	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BKP64_RS11415	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BKP64_RS11420	COG0730	response to heat
BKP64_RS11435	COG0142	geranyltranstransferase activity
BKP64_RS11440	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BKP64_RS11445	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BKP64_RS11450	COG0315	cyclic pyranopterin monophosphate synthase activity
BKP64_RS11455	COG0494	nUDIX hydrolase
BKP64_RS11460	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BKP64_RS11465	COG0653	protein targeting
BKP64_RS11470	COG0739	heme binding
BKP64_RS11480	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BKP64_RS11495	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BKP64_RS11500	COG1181	Belongs to the D-alanine--D-alanine ligase family
BKP64_RS11505	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BKP64_RS11510	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BKP64_RS11515	COG0772	Belongs to the SEDS family
BKP64_RS11520	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BKP64_RS11525	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BKP64_RS11530	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BKP64_RS11545	COG3116	cell division
BKP64_RS11550	COG0275	rRNA processing
BKP64_RS11555	COG2001	Belongs to the MraZ family
BKP64_RS11565	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BKP64_RS11575	COG0792	nuclease activity
BKP64_RS11585	COG2969	positive regulation of protein catabolic process
BKP64_RS11590	COG0625	glutathione transferase activity
BKP64_RS11595	COG2857	Cytochrome c1
BKP64_RS11600	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BKP64_RS11605	COG0723	plastoquinol--plastocyanin reductase activity
BKP64_RS11610	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BKP64_RS11615	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BKP64_RS11620	COG0084	hydrolase, TatD family'
BKP64_RS11625	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BKP64_RS11640	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BKP64_RS11670	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
BKP64_RS11680	COG1183	phosphatidylcholine synthase activity
BKP64_RS11685	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BKP64_RS11690	COG0440	acetolactate synthase activity
BKP64_RS11695	COG0028	Belongs to the TPP enzyme family
BKP64_RS11705	COG0542	response to heat
BKP64_RS11725	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BKP64_RS11725	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BKP64_RS11780	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BKP64_RS11785	COG1047	Peptidyl-prolyl cis-trans
BKP64_RS11795	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BKP64_RS11800	COG0196	riboflavin kinase activity
BKP64_RS11805	COG0728	peptidoglycan biosynthetic process
BKP64_RS11810	COG0268	Binds directly to 16S ribosomal RNA
BKP64_RS11815	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BKP64_RS11820	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BKP64_RS11825	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BKP64_RS11830	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BKP64_RS11835	COG0142	geranyltranstransferase activity
BKP64_RS11840	COG0435	Glutathione S-transferase
BKP64_RS11845	COG0583	DNA-binding transcription factor activity
BKP64_RS11860	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BKP64_RS11870	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BKP64_RS11875	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BKP64_RS11885	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BKP64_RS11885	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BKP64_RS11890	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BKP64_RS11895	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BKP64_RS11900	COG0488	(ABC) transporter
BKP64_RS11915	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BKP64_RS11920	COG0493	'glutamate synthase
BKP64_RS11925	COG0069	glutamate synthase activity
BKP64_RS11925	COG0067	glutamate synthase
BKP64_RS11925	COG0070	glutamate synthase
BKP64_RS11935	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BKP64_RS11940	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BKP64_RS11975	COG0281	malic enzyme
BKP64_RS11980	COG0254	rRNA binding
BKP64_RS11985	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BKP64_RS11995	COG0018	arginyl-trna synthetase
BKP64_RS12005	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BKP64_RS12010	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BKP64_RS12025	COG0494	nUDIX hydrolase
BKP64_RS12040	COG0509	glycine decarboxylation via glycine cleavage system
BKP64_RS12045	COG0583	DNA-binding transcription factor activity
BKP64_RS12050	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BKP64_RS12055	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BKP64_RS12060	COG3151	Protein conserved in bacteria
BKP64_RS12065	COG0494	nUDIX hydrolase
BKP64_RS12070	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BKP64_RS12075	COG1538	Outer membrane efflux protein
BKP64_RS12080	COG1519	Transferase
BKP64_RS12085	COG1560	Kdo2-lipid A biosynthetic process
BKP64_RS12105	COG0463	Glycosyl transferase, family 2
BKP64_RS12120	COG0463	Glycosyl transferase, family 2
BKP64_RS12135	COG0297	glycogen (starch) synthase activity
BKP64_RS12140	COG3642	lipopolysaccharide core region biosynthetic process
BKP64_RS12145	COG0859	PFAM glycosyl transferase family 9
BKP64_RS12160	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BKP64_RS12170	COG3025	triphosphatase activity
BKP64_RS12185	COG1490	D-aminoacyl-tRNA deacylase activity
BKP64_RS12195	COG1217	gtp-binding protein TYPA
BKP64_RS12200	COG0174	glutamine synthetase
BKP64_RS12210	COG3852	Histidine kinase
BKP64_RS12215	COG2204	response regulator
BKP64_RS12245	COG2165	general secretion pathway protein
BKP64_RS12260	COG1459	type II secretion system
BKP64_RS12265	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BKP64_RS12275	COG3409	Peptidoglycan-binding domain 1 protein
BKP64_RS12275	COG3267	Type II secretory pathway component ExeA
BKP64_RS12310	COG2814	Major facilitator Superfamily
BKP64_RS12320	COG0203	ribosomal protein L17
BKP64_RS12325	COG0202	RNA polymerase activity
BKP64_RS12330	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BKP64_RS12335	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BKP64_RS12340	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BKP64_RS12350	COG0200	Binds to the 23S rRNA
BKP64_RS12355	COG1841	ribosomal large subunit assembly
BKP64_RS12360	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BKP64_RS12365	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BKP64_RS12370	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BKP64_RS12375	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BKP64_RS12380	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BKP64_RS12385	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BKP64_RS12390	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BKP64_RS12395	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BKP64_RS12400	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BKP64_RS12405	COG0255	Belongs to the universal ribosomal protein uL29 family
BKP64_RS12410	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BKP64_RS12415	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BKP64_RS12420	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BKP64_RS12425	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BKP64_RS12430	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BKP64_RS12435	COG0089	rRNA binding
BKP64_RS12440	COG0088	Forms part of the polypeptide exit tunnel
BKP64_RS12445	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BKP64_RS12450	COG0051	transcription antitermination factor activity, RNA binding
BKP64_RS12455	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BKP64_RS12460	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BKP64_RS12465	COG0049	tRNA binding
BKP64_RS12470	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BKP64_RS12475	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BKP64_RS12480	COG0085	RNA polymerase activity
BKP64_RS12485	COG0222	ribosome binding
BKP64_RS12490	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BKP64_RS12495	COG0081	regulation of translation
BKP64_RS12500	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BKP64_RS12520	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BKP64_RS12550	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BKP64_RS12555	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BKP64_RS12555	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BKP64_RS12585	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BKP64_RS12590	COG0739	heme binding
BKP64_RS12595	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BKP64_RS12600	COG0316	Belongs to the HesB IscA family
BKP64_RS12615	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BKP64_RS12625	COG1981	membrane
BKP64_RS12630	COG0352	thiamine-phosphate diphosphorylase activity
BKP64_RS12630	COG0351	phosphomethylpyrimidine kinase
BKP64_RS12635	COG0352	thiamine-phosphate diphosphorylase activity
BKP64_RS12640	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BKP64_RS12645	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BKP64_RS12680	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BKP64_RS12695	COG1489	DNA binding
BKP64_RS12710	COG5002	protein histidine kinase activity
BKP64_RS12720	COG0617	tRNA 3'-terminal CCA addition
BKP64_RS12725	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BKP64_RS12730	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BKP64_RS12735	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BKP64_RS12740	COG0166	Belongs to the GPI family
BKP64_RS12745	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BKP64_RS12750	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BKP64_RS12755	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BKP64_RS12760	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BKP64_RS12765	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BKP64_RS12770	COG0358	DNA primase activity
BKP64_RS12815	COG0243	molybdopterin cofactor binding
BKP64_RS12830	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BKP64_RS12835	COG0583	DNA-binding transcription factor activity
BKP64_RS12850	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BKP64_RS12855	COG1758	RNA polymerase activity
BKP64_RS12865	COG1561	YicC-like family, N-terminal region
BKP64_RS12870	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BKP64_RS12880	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BKP64_RS12940	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BKP64_RS12945	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BKP64_RS12960	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BKP64_RS12965	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BKP64_RS12975	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BKP64_RS12980	COG0606	chelatase, subunit chli
BKP64_RS12985	COG2960	long-chain fatty acid transporting porin activity
BKP64_RS12990	COG0347	Belongs to the P(II) protein family
BKP64_RS12995	COG0004	ammonium transporteR
BKP64_RS13000	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BKP64_RS13005	COG1166	arginine decarboxylase activity
BKP64_RS13010	COG1595	DNA-templated transcription, initiation
BKP64_RS13030	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BKP64_RS13035	COG3263	regulation of cellular component size
BKP64_RS13040	COG3321	synthase
BKP64_RS13040	COG0604	alcohol dehydrogenase
BKP64_RS13055	COG0596	Alpha beta hydrolase
BKP64_RS13075	COG1752	Esterase of the alpha-beta hydrolase superfamily
BKP64_RS13090	COG2205	protein histidine kinase activity
BKP64_RS13090	COG2198	Histidine kinase
BKP64_RS13090	COG0784	Response regulator, receiver
BKP64_RS13105	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BKP64_RS13115	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BKP64_RS13120	COG0019	diaminopimelate decarboxylase activity
BKP64_RS13130	COG3072	Adenylate cyclase
BKP64_RS13135	COG5002	protein histidine kinase activity
BKP64_RS13135	COG5001	Diguanylate cyclase
BKP64_RS13140	COG0165	Argininosuccinate lyase
BKP64_RS13145	COG3275	phosphorelay sensor kinase activity
BKP64_RS13155	COG0181	hydroxymethylbilane synthase activity
BKP64_RS13165	COG2959	enzyme of heme biosynthesis
BKP64_RS13180	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BKP64_RS13190	COG0521	Mo-molybdopterin cofactor biosynthetic process
BKP64_RS13195	COG0303	'Molybdopterin
BKP64_RS13200	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BKP64_RS13205	COG0314	molybdopterin synthase activity
BKP64_RS13245	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BKP64_RS13260	COG2918	glutathione biosynthetic process
BKP64_RS13265	COG2183	response to ionizing radiation
BKP64_RS13310	COG0006	proline dipeptidase activity
BKP64_RS13315	COG0583	DNA-binding transcription factor activity
BKP64_RS13320	COG4608	Belongs to the ABC transporter superfamily
BKP64_RS13325	COG0444	Belongs to the ABC transporter superfamily
BKP64_RS13330	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BKP64_RS13335	COG0601	transmembrane transport
BKP64_RS13345	COG1346	cytolysis
BKP64_RS13350	COG1380	Effector of murein hydrolase LrgA
BKP64_RS13355	COG4681	YaeQ
BKP64_RS13385	COG1126	abc transporter atp-binding protein
BKP64_RS13395	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BKP64_RS13400	COG0746	molybdenum cofactor guanylyltransferase activity
BKP64_RS13405	COG1763	Mo-molybdopterin cofactor biosynthetic process
BKP64_RS13410	COG0303	'Molybdopterin
BKP64_RS13425	COG0489	protein tyrosine kinase activity
BKP64_RS13460	COG0437	4 iron, 4 sulfur cluster binding
BKP64_RS13465	COG2864	formate dehydrogenase
BKP64_RS13475	COG3384	dioxygenase
BKP64_RS13480	COG0435	Glutathione S-transferase
BKP64_RS13485	COG2259	Doxx family
BKP64_RS13490	COG0583	DNA-binding transcription factor activity
BKP64_RS13495	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BKP64_RS13505	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BKP64_RS13525	COG1022	Amp-dependent synthetase and ligase
BKP64_RS13555	COG1024	Enoyl-CoA hydratase
BKP64_RS13560	COG4302	ethanolamine ammonia-lyase activity
BKP64_RS13570	COG4191	Histidine kinase
BKP64_RS13575	COG2204	response regulator
BKP64_RS13590	COG0559	Belongs to the binding-protein-dependent transport system permease family
BKP64_RS13600	COG0411	ABC transporter
BKP64_RS13610	COG1454	alcohol dehydrogenase
BKP64_RS13620	COG0824	Thioesterase
BKP64_RS13645	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKP64_RS13660	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BKP64_RS13665	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BKP64_RS13670	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BKP64_RS13675	COG0589	response to stress
BKP64_RS13685	COG1177	transmembrane transport
BKP64_RS13695	COG3842	ATPase activity
BKP64_RS13700	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BKP64_RS13705	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BKP64_RS13710	COG1177	transmembrane transport
BKP64_RS13720	COG3842	ATPase activity
BKP64_RS13725	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BKP64_RS13735	COG0840	transmembrane signaling receptor activity
BKP64_RS13760	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BKP64_RS13785	COG3300	MHYT domain
BKP64_RS13785	COG5001	Diguanylate cyclase
BKP64_RS13820	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BKP64_RS13840	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BKP64_RS13845	COG4569	acetaldehyde dehydrogenase (acetylating) activity
BKP64_RS13940	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
BKP64_RS13945	COG0415	Belongs to the DNA photolyase family
BKP64_RS13955	COG1233	COG1233 Phytoene dehydrogenase and related
BKP64_RS13960	COG3339	Conserved Protein
BKP64_RS13965	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BKP64_RS13975	COG0004	ammonium transporteR
BKP64_RS13980	COG2308	Evidence 4 Homologs of previously reported genes of
BKP64_RS13990	COG1305	Transglutaminase-like
BKP64_RS14010	COG1136	(ABC) transporter
BKP64_RS14050	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BKP64_RS14055	COG2235	arginine
BKP64_RS14060	COG1288	antiporter activity
BKP64_RS14075	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
BKP64_RS14125	COG0463	Glycosyl transferase, family 2
BKP64_RS14130	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BKP64_RS14140	COG0642	Histidine kinase
BKP64_RS14150	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
BKP64_RS14155	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BKP64_RS14160	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BKP64_RS14165	COG4206	TonB-dependent receptor
BKP64_RS14170	COG0516	GMP reductase activity
BKP64_RS14180	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BKP64_RS14180	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BKP64_RS14185	COG5002	protein histidine kinase activity
BKP64_RS14190	COG0745	RESPONSE REGULATOR receiver
BKP64_RS14220	COG1960	acyl-CoA dehydrogenase activity
BKP64_RS14225	COG0183	Belongs to the thiolase family
BKP64_RS14230	COG1250	3-hydroxyacyl-CoA dehydrogenase
BKP64_RS14230	COG1024	Enoyl-CoA hydratase
BKP64_RS14240	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BKP64_RS14250	COG0183	Belongs to the thiolase family
BKP64_RS14255	COG1960	acyl-CoA dehydrogenase activity
BKP64_RS14270	COG1960	acyl-CoA dehydrogenase activity
BKP64_RS14275	COG1960	acyl-CoA dehydrogenase activity
BKP64_RS14280	COG0235	Class ii aldolase
BKP64_RS14290	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BKP64_RS14300	COG0410	ABC transporter
BKP64_RS14315	COG0559	Belongs to the binding-protein-dependent transport system permease family
BKP64_RS14320	COG0318	PFAM AMP-dependent synthetase and ligase
BKP64_RS14325	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BKP64_RS14335	COG1028	Short-chain dehydrogenase reductase Sdr
BKP64_RS14350	COG1028	Short-chain dehydrogenase reductase Sdr
BKP64_RS14360	COG1024	Enoyl-CoA hydratase
BKP64_RS14370	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BKP64_RS14375	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BKP64_RS14380	COG0840	transmembrane signaling receptor activity
BKP64_RS14390	COG0534	Mate efflux family protein
BKP64_RS14410	COG1115	amino acid carrier protein
BKP64_RS14415	COG0450	alkyl hydroperoxide reductase
BKP64_RS14425	COG2011	ABC-type metal ion transport system permease component
BKP64_RS14460	COG5002	protein histidine kinase activity
BKP64_RS14460	COG3447	MASE1 domain protein
BKP64_RS14460	COG5001	Diguanylate cyclase
BKP64_RS14465	COG0811	peptide transport
BKP64_RS14490	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BKP64_RS14500	COG0121	glutamine amidotransferase
BKP64_RS14540	COG5001	Diguanylate cyclase
BKP64_RS14540	COG3300	MHYT domain
BKP64_RS14545	COG0259	pyridoxamine-phosphate oxidase activity
BKP64_RS14550	COG2091	lysine biosynthetic process via aminoadipic acid
BKP64_RS14575	COG0527	aspartate kinase activity
BKP64_RS14580	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BKP64_RS14635	COG0398	Pfam SNARE associated Golgi protein
BKP64_RS14655	COG1881	PFAM PEBP family protein
BKP64_RS14680	COG0348	domain, Protein
BKP64_RS14680	COG3901	Regulator of nitric oxide reductase transcription
BKP64_RS14685	COG1252	NADH dehydrogenase
BKP64_RS14690	COG1012	belongs to the aldehyde dehydrogenase family
BKP64_RS14695	COG1177	transmembrane transport
BKP64_RS14700	COG1176	ABC-type spermidine putrescine transport system, permease component I
BKP64_RS14705	COG3842	ATPase activity
BKP64_RS14710	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BKP64_RS14715	COG0583	DNA-binding transcription factor activity
BKP64_RS14730	COG3263	regulation of cellular component size
BKP64_RS14745	COG0330	HflC and HflK could
BKP64_RS14750	COG1030	water channel activity
BKP64_RS14755	COG1388	LysM domain
BKP64_RS14755	COG1376	ErfK ybiS ycfS ynhG family protein
BKP64_RS14760	COG2119	membrane
BKP64_RS14765	COG2814	Major facilitator Superfamily
BKP64_RS14795	COG0602	queuosine metabolic process
BKP64_RS14800	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BKP64_RS14850	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BKP64_RS14855	COG3706	GGDEF domain
BKP64_RS14860	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BKP64_RS14875	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BKP64_RS14880	COG1028	Short-chain dehydrogenase reductase Sdr
BKP64_RS14885	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BKP64_RS14895	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BKP64_RS14925	COG1917	Cupin 2, conserved barrel domain protein
BKP64_RS14940	COG0189	ligase activity
BKP64_RS14945	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BKP64_RS14950	COG1643	Atp-dependent helicase
BKP64_RS14960	COG0109	protoheme IX farnesyltransferase activity
BKP64_RS14990	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BKP64_RS14995	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BKP64_RS14995	COG1565	acr, cog1565
BKP64_RS15000	COG0534	Mate efflux family protein
BKP64_RS15035	COG2203	Gaf domain
BKP64_RS15035	COG4251	negative regulation of phosphorylation
BKP64_RS15035	COG5001	Diguanylate cyclase
BKP64_RS15035	COG3706	GGDEF domain
BKP64_RS15045	COG2056	Na+-H+ antiporter family
BKP64_RS15055	COG0339	signal peptide processing
BKP64_RS15060	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BKP64_RS15065	COG0071	Belongs to the small heat shock protein (HSP20) family
BKP64_RS15080	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BKP64_RS15085	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BKP64_RS15090	COG0408	coproporphyrinogen oxidase activity
BKP64_RS15095	COG0009	L-threonylcarbamoyladenylate synthase
BKP64_RS15100	COG0758	DNA mediated transformation
BKP64_RS15105	COG1652	LysM domain
BKP64_RS15110	COG0242	peptide deformylase activity
BKP64_RS15115	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BKP64_RS15125	COG0569	domain protein
BKP64_RS15130	COG0752	glycyl-tRNA synthetase alpha subunit
BKP64_RS15135	COG0751	glycine-tRNA ligase activity
BKP64_RS15150	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BKP64_RS15160	COG0450	alkyl hydroperoxide reductase
BKP64_RS15205	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BKP64_RS15210	COG1074	ATP-dependent DNA helicase activity
BKP64_RS15215	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BKP64_RS15220	COG5265	(ABC) transporter
BKP64_RS15230	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BKP64_RS15245	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BKP64_RS15255	COG0592	DNA-directed DNA polymerase activity
BKP64_RS15260	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BKP64_RS15270	COG0706	membrane insertase activity
BKP64_RS15275	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BKP64_RS15285	COG0463	Glycosyl transferase, family 2
BKP64_RS15295	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BKP64_RS15305	COG2200	EAL domain
BKP64_RS15305	COG2199	diguanylate cyclase activity
BKP64_RS15305	COG3287	FIST C domain
BKP64_RS15310	COG1960	acyl-CoA dehydrogenase activity
BKP64_RS15320	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BKP64_RS15325	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BKP64_RS15330	COG4943	cyclic-guanylate-specific phosphodiesterase activity
BKP64_RS15335	COG0477	Major facilitator Superfamily
BKP64_RS15340	COG0445	tRNA wobble uridine modification
BKP64_RS15345	COG0357	Ribosomal RNA small subunit methyltransferase G
BKP64_RS15350	COG1192	Involved in chromosome partitioning
BKP64_RS15355	COG1475	DNA binding
BKP64_RS15365	COG0356	it plays a direct role in the translocation of protons across the membrane
BKP64_RS15375	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BKP64_RS15380	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BKP64_RS15385	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BKP64_RS15390	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BKP64_RS15395	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BKP64_RS15400	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BKP64_RS15405	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BKP64_RS15410	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BKP64_RS15420	COG1846	Transcriptional regulator
BKP64_RS15425	COG1960	acyl-CoA dehydrogenase activity
BKP64_RS15430	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BKP64_RS15440	COG0318	PFAM AMP-dependent synthetase and ligase
BKP64_RS15445	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BKP64_RS15465	COG0784	Response regulator, receiver
BKP64_RS15465	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BKP64_RS15465	COG2198	Histidine kinase
BKP64_RS15465	COG2205	protein histidine kinase activity
BKP64_RS15495	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BKP64_RS15545	COG2329	Antibiotic biosynthesis monooxygenase
BKP64_RS15550	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BKP64_RS15555	COG3706	GGDEF domain
BKP64_RS15560	COG2207	Transcriptional regulator
BKP64_RS15570	COG2020	methyltransferase activity
BKP64_RS15595	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BKP64_RS15635	COG3239	Fatty acid desaturase
BKP64_RS15640	COG0243	molybdopterin cofactor binding
BKP64_RS15675	COG1024	Enoyl-CoA hydratase
BKP64_RS15685	COG4948	Mandelate Racemase Muconate Lactonizing
BKP64_RS15705	COG0598	Magnesium transport protein CorA
BKP64_RS15720	COG1309	transcriptional regulator
BKP64_RS15725	COG1012	belongs to the aldehyde dehydrogenase family
BKP64_RS15730	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
BKP64_RS15745	COG0678	peroxiredoxin activity
BKP64_RS15750	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BKP64_RS15760	COG3634	alkyl hydroperoxide reductase activity
BKP64_RS15775	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BKP64_RS15780	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
BKP64_RS15785	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BKP64_RS15795	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BKP64_RS15805	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BKP64_RS15820	COG1560	Kdo2-lipid A biosynthetic process
BKP64_RS15830	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BKP64_RS15835	COG0513	Belongs to the DEAD box helicase family
BKP64_RS15855	COG3047	cAMP biosynthetic process
BKP64_RS15875	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
BKP64_RS15880	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BKP64_RS15885	COG2194	sulfuric ester hydrolase activity
BKP64_RS15895	COG1028	Short-chain dehydrogenase reductase Sdr
BKP64_RS15900	COG1960	acyl-CoA dehydrogenase activity
BKP64_RS15905	COG1960	acyl-CoA dehydrogenase activity
BKP64_RS15910	COG0183	Belongs to the thiolase family
BKP64_RS15915	COG1024	Enoyl-CoA hydratase
BKP64_RS15915	COG1250	3-hydroxyacyl-CoA dehydrogenase
BKP64_RS15925	COG2095	MarC family integral membrane protein
BKP64_RS15940	COG2814	Major facilitator Superfamily
BKP64_RS15990	COG0583	DNA-binding transcription factor activity
BKP64_RS16030	COG1960	acyl-CoA dehydrogenase activity
BKP64_RS16050	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BKP64_RS16060	COG0697	spore germination
BKP64_RS16065	COG3608	succinylglutamate desuccinylase aspartoacylase
BKP64_RS16085	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BKP64_RS16090	COG2814	Major facilitator Superfamily
BKP64_RS16095	COG0583	DNA-binding transcription factor activity
BKP64_RS16110	COG3243	poly(R)-hydroxyalkanoic acid synthase
BKP64_RS16115	COG0204	Acyl-transferase
BKP64_RS16125	COG0557	exoribonuclease II activity
BKP64_RS16130	COG3706	GGDEF domain
BKP64_RS16140	COG2217	Heavy metal translocating P-type atpase
BKP64_RS16165	COG1832	CoA-binding protein
BKP64_RS16170	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BKP64_RS16175	COG0302	gtp cyclohydrolase
BKP64_RS16205	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BKP64_RS16210	COG1121	(ABC) transporter
BKP64_RS16215	COG0735	belongs to the Fur family
BKP64_RS16225	COG2201	protein-glutamate methylesterase activity
BKP64_RS16230	COG0643	Histidine kinase
BKP64_RS16230	COG2198	Histidine kinase
BKP64_RS16230	COG0784	Response regulator, receiver
BKP64_RS16240	COG0840	transmembrane signaling receptor activity
BKP64_RS16260	COG0189	ligase activity
BKP64_RS16270	COG1678	Uncharacterized ACR, COG1678
BKP64_RS16275	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BKP64_RS16285	COG0540	Belongs to the ATCase OTCase family
BKP64_RS16325	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BKP64_RS16335	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BKP64_RS16340	COG1011	Hydrolase
BKP64_RS16350	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BKP64_RS16360	COG0742	ribosomal rna small subunit methyltransferase
BKP64_RS16365	COG0552	protein localization to endoplasmic reticulum
BKP64_RS16370	COG2884	Cell division ATP-binding protein ftsE
BKP64_RS16375	COG2177	Part of the ABC transporter FtsEX involved in
BKP64_RS16385	COG2084	Dehydrogenase
BKP64_RS16390	COG3622	Belongs to the hyi family
BKP64_RS16400	COG2205	protein histidine kinase activity
BKP64_RS16410	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BKP64_RS16430	COG2200	EAL domain
BKP64_RS16430	COG2199	diguanylate cyclase activity
BKP64_RS16430	COG3287	FIST C domain
BKP64_RS16470	COG3706	GGDEF domain
BKP64_RS16495	COG2205	protein histidine kinase activity
BKP64_RS16500	COG0745	RESPONSE REGULATOR receiver
BKP64_RS16505	COG2304	oxidoreductase activity
BKP64_RS16545	COG1132	(ABC) transporter
BKP64_RS16550	COG0840	transmembrane signaling receptor activity
BKP64_RS16560	COG2202	Pas domain
BKP64_RS16560	COG2205	protein histidine kinase activity
BKP64_RS16565	COG5002	protein histidine kinase activity
BKP64_RS16570	COG5002	protein histidine kinase activity
BKP64_RS16580	COG0745	RESPONSE REGULATOR receiver
BKP64_RS16585	COG0745	RESPONSE REGULATOR receiver
BKP64_RS16600	COG2431	L-lysine efflux transmembrane transporter activity
BKP64_RS16625	COG0084	hydrolase, TatD family'
BKP64_RS16645	COG2885	chlorophyll binding
BKP64_RS16650	COG0210	DNA helicase
BKP64_RS16660	COG1444	tRNA N-acetyltransferase activity
BKP64_RS16670	COG1024	Enoyl-CoA hydratase
BKP64_RS16680	COG1611	Belongs to the LOG family
BKP64_RS16685	COG0301	tRNA thio-modification
BKP64_RS16685	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BKP64_RS16700	COG0210	DNA helicase
BKP64_RS16705	COG1968	undecaprenyl-diphosphatase activity
BKP64_RS16710	COG0798	PFAM Bile acid sodium symporter
BKP64_RS16715	COG0431	NADPH-dependent FMN reductase
BKP64_RS16720	COG0640	Transcriptional regulator
BKP64_RS16725	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BKP64_RS16750	COG1013	pyruvate-flavodoxin oxidoreductase activity
BKP64_RS16750	COG0674	pyruvate-flavodoxin oxidoreductase activity
BKP64_RS16750	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BKP64_RS16770	COG0573	inorganic phosphate transmembrane transporter activity
BKP64_RS16775	COG0581	inorganic phosphate transmembrane transporter activity
BKP64_RS16780	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BKP64_RS16790	COG0537	adenosine 5'-monophosphoramidase activity
BKP64_RS16795	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BKP64_RS16805	COG0668	transmembrane transport
BKP64_RS16810	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
BKP64_RS16825	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
BKP64_RS16830	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BKP64_RS16840	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BKP64_RS16845	COG1278	Cold shock
BKP64_RS16860	COG0686	Belongs to the AlaDH PNT family
BKP64_RS16865	COG0625	glutathione transferase activity
BKP64_RS16880	COG0129	dihydroxy-acid dehydratase activity
BKP64_RS16885	COG2203	Gaf domain
BKP64_RS16885	COG3706	GGDEF domain
BKP64_RS16885	COG4251	negative regulation of phosphorylation
BKP64_RS16885	COG5001	Diguanylate cyclase
BKP64_RS16890	COG1686	Belongs to the peptidase S11 family
BKP64_RS16895	COG0252	asparaginase activity
BKP64_RS16900	COG1187	pseudouridine synthase activity
BKP64_RS16910	COG2951	lytic endotransglycosylase activity
BKP64_RS16915	COG0745	RESPONSE REGULATOR receiver
BKP64_RS16930	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BKP64_RS16935	COG3161	chorismate lyase activity
BKP64_RS16940	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BKP64_RS16955	COG1946	Acyl-CoA thioesterase
BKP64_RS16960	COG3706	GGDEF domain
BKP64_RS16960	COG4251	negative regulation of phosphorylation
BKP64_RS16960	COG2203	Gaf domain
BKP64_RS16960	COG5001	Diguanylate cyclase
BKP64_RS16975	COG0306	phosphate transporter
BKP64_RS16985	COG0076	glutamate decarboxylase activity
BKP64_RS16995	COG1960	acyl-CoA dehydrogenase activity
BKP64_RS17000	COG1309	transcriptional regulator
BKP64_RS17010	COG5380	lipid catabolic process
BKP64_RS17020	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BKP64_RS17030	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BKP64_RS17035	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BKP64_RS17060	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BKP64_RS17080	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BKP64_RS17085	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BKP64_RS17090	COG2003	Belongs to the UPF0758 family
BKP64_RS17095	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BKP64_RS17100	COG0756	dUTP diphosphatase activity
BKP64_RS17110	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BKP64_RS17120	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BKP64_RS17125	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BKP64_RS17125	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BKP64_RS17140	COG3954	Phosphoribulokinase
BKP64_RS17150	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BKP64_RS17155	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BKP64_RS17160	COG1765	OsmC-like protein
BKP64_RS17170	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BKP64_RS17185	COG2267	carboxylic ester hydrolase activity
BKP64_RS17205	COG4175	Glycine betaine
BKP64_RS17205	COG0517	IMP dehydrogenase activity
BKP64_RS17210	COG4176	ABC-type proline glycine betaine transport system permease component
BKP64_RS17235	COG0625	glutathione transferase activity
BKP64_RS17245	COG0134	indole-3-glycerol-phosphate synthase activity
BKP64_RS17250	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BKP64_RS17255	COG0512	Glutamine amidotransferase of anthranilate synthase
BKP64_RS17260	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BKP64_RS17265	COG0546	phosphoglycolate phosphatase activity
BKP64_RS17270	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BKP64_RS17280	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BKP64_RS17285	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BKP64_RS17290	COG3178	'Phosphotransferase
BKP64_RS17295	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BKP64_RS17300	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BKP64_RS17305	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BKP64_RS17310	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BKP64_RS17315	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BKP64_RS17320	COG2363	Small membrane protein
BKP64_RS17330	COG2022	thiamine diphosphate biosynthetic process
BKP64_RS17335	COG1309	transcriptional regulator
BKP64_RS17355	COG2197	response regulator
BKP64_RS17370	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BKP64_RS17380	COG0840	transmembrane signaling receptor activity
BKP64_RS17385	COG2203	Gaf domain
BKP64_RS17385	COG3706	GGDEF domain
BKP64_RS17385	COG5001	Diguanylate cyclase
BKP64_RS17385	COG4251	negative regulation of phosphorylation
BKP64_RS17395	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BKP64_RS17400	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BKP64_RS17415	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BKP64_RS17420	COG1280	lysine exporter protein (LysE YggA)
BKP64_RS17425	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BKP64_RS17430	COG0783	Belongs to the Dps family
BKP64_RS17440	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BKP64_RS17455	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BKP64_RS17465	COG3525	Glycosyl hydrolase, family 20, catalytic domain
BKP64_RS17475	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
BKP64_RS17490	COG0659	secondary active sulfate transmembrane transporter activity
BKP64_RS17555	COG4651	solute:proton antiporter activity
BKP64_RS17555	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BKP64_RS17565	COG0151	Belongs to the GarS family
BKP64_RS17590	COG2264	protein methyltransferase activity
BKP64_RS17600	COG0511	ligase activity, forming carbon-carbon bonds
BKP64_RS17605	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BKP64_RS17615	COG3300	MHYT domain
BKP64_RS17615	COG5001	Diguanylate cyclase
BKP64_RS17630	COG1960	acyl-CoA dehydrogenase activity
BKP64_RS17635	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BKP64_RS17640	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BKP64_RS17645	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BKP64_RS17670	COG4181	ATPase activity
BKP64_RS17685	COG3079	Belongs to the UPF0149 family
BKP64_RS17690	COG0006	proline dipeptidase activity
BKP64_RS17695	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BKP64_RS17700	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BKP64_RS17720	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BKP64_RS17730	COG2354	Protein conserved in bacteria
BKP64_RS17745	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BKP64_RS17750	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BKP64_RS17755	COG0140	phosphoribosyl-ATP diphosphatase activity
BKP64_RS17760	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BKP64_RS17765	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BKP64_RS17775	COG2226	methyltransferase
BKP64_RS17810	COG0784	Response regulator, receiver
BKP64_RS17810	COG2205	protein histidine kinase activity
BKP64_RS17825	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BKP64_RS17840	COG1131	(ABC) transporter
BKP64_RS17870	COG1116	anion transmembrane transporter activity
BKP64_RS17880	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BKP64_RS17900	COG0385	Bile acid
BKP64_RS17905	COG1309	transcriptional regulator
BKP64_RS17915	COG0439	Biotin carboxylase
BKP64_RS17935	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BKP64_RS17950	COG0535	radical SAM domain protein
BKP64_RS17965	COG2205	protein histidine kinase activity
BKP64_RS17965	COG0784	Response regulator, receiver
BKP64_RS17990	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BKP64_RS18015	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BKP64_RS18020	COG0579	oxidoreductase
BKP64_RS18035	COG0028	Belongs to the TPP enzyme family
BKP64_RS18045	COG0835	chemotaxis
BKP64_RS18045	COG0784	Response regulator, receiver
BKP64_RS18050	COG1028	Short-chain dehydrogenase reductase Sdr
BKP64_RS18175	COG3311	Transcriptional regulator
BKP64_RS18185	COG0582	viral genome integration into host DNA
BKP64_RS18200	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BKP64_RS18210	COG2867	negative regulation of translational initiation
BKP64_RS18215	COG2914	Belongs to the UPF0125 (RnfH) family
BKP64_RS18230	COG0497	DNA recombination
BKP64_RS18240	COG0443	Heat shock 70 kDa protein
BKP64_RS18245	COG0484	heat shock protein binding
BKP64_RS18250	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BKP64_RS18260	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BKP64_RS18265	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BKP64_RS18275	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BKP64_RS18280	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BKP64_RS18285	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BKP64_RS18290	COG0149	triose-phosphate isomerase activity
BKP64_RS18305	COG0779	Required for maturation of 30S ribosomal subunits
BKP64_RS18310	COG0195	Participates in both transcription termination and antitermination
BKP64_RS18315	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BKP64_RS18320	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BKP64_RS18325	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BKP64_RS18330	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BKP64_RS18335	COG1185	polyribonucleotide nucleotidyltransferase activity
BKP64_RS18400	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BKP64_RS18405	COG3118	belongs to the thioredoxin family
BKP64_RS18410	COG3327	negative regulation of DNA-templated transcription, initiation
BKP64_RS18425	COG4177	L-phenylalanine transmembrane transporter activity
BKP64_RS18440	COG2030	dehydratase
BKP64_RS18440	COG1012	belongs to the aldehyde dehydrogenase family
BKP64_RS18445	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BKP64_RS18450	COG2151	metal-sulfur cluster biosynthetic enzyme
BKP64_RS18455	COG3396	Phenylacetate-CoA oxygenase
BKP64_RS18460	COG3460	Phenylacetate-CoA oxygenase
BKP64_RS18465	COG3396	Phenylacetate-CoA oxygenase
BKP64_RS18475	COG0183	Belongs to the thiolase family
BKP64_RS18480	COG2050	protein possibly involved in aromatic compounds catabolism
BKP64_RS18485	COG1250	3-hydroxyacyl-CoA dehydrogenase
BKP64_RS18490	COG1024	Enoyl-CoA hydratase
BKP64_RS18505	COG1509	lysine 2,3-aminomutase activity
BKP64_RS18530	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BKP64_RS18545	COG1012	belongs to the aldehyde dehydrogenase family
BKP64_RS18550	COG3724	N-succinylarginine dihydrolase activity
BKP64_RS18565	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BKP64_RS18570	COG2988	succinylglutamate desuccinylase activity
BKP64_RS18575	COG4160	amino acid transport
BKP64_RS18580	COG4215	(ABC) transporter
BKP64_RS18585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BKP64_RS18595	COG2186	Transcriptional regulator
BKP64_RS18600	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BKP64_RS18610	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BKP64_RS18620	COG0277	FAD linked oxidase domain protein
BKP64_RS18625	COG0277	FAD linked oxidase domain protein
BKP64_RS18630	COG0247	lactate metabolic process
BKP64_RS18655	COG0747	negative chemotaxis
BKP64_RS18665	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BKP64_RS18685	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
BKP64_RS18690	COG1194	a g-specific adenine glycosylase
BKP64_RS18705	COG0131	Imidazoleglycerol-phosphate dehydratase
BKP64_RS18710	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BKP64_RS18715	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BKP64_RS18720	COG0107	imidazoleglycerol-phosphate synthase activity
BKP64_RS18730	COG0793	Belongs to the peptidase S41A family
BKP64_RS18735	COG4942	peptidase
BKP64_RS18740	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BKP64_RS18745	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BKP64_RS18750	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
BKP64_RS18755	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BKP64_RS18760	COG0183	Belongs to the thiolase family
BKP64_RS18765	COG1028	Short-chain dehydrogenase reductase Sdr
BKP64_RS18770	COG0617	tRNA 3'-terminal CCA addition
BKP64_RS18790	COG2166	iron-sulfur cluster assembly
BKP64_RS18795	COG2151	metal-sulfur cluster biosynthetic enzyme
BKP64_RS18800	COG0316	Belongs to the HesB IscA family
BKP64_RS18805	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BKP64_RS18810	COG0719	Fe-S assembly protein
BKP64_RS18815	COG0396	ATPase activity
BKP64_RS18820	COG0719	Fe-S assembly protein
BKP64_RS18825	COG0826	peptidase U32
BKP64_RS18840	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BKP64_RS18870	COG2223	nitrite transmembrane transporter activity
BKP64_RS18880	COG2223	nitrite transmembrane transporter activity
BKP64_RS18890	COG1272	protein, Hemolysin III
BKP64_RS18915	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BKP64_RS18925	COG1230	cation diffusion facilitator family transporter
BKP64_RS18930	COG1999	signal sequence binding
BKP64_RS18940	COG0546	phosphoglycolate phosphatase activity
BKP64_RS18950	COG3046	protein related to deoxyribodipyrimidine photolyase
BKP64_RS18960	COG0826	peptidase U32
BKP64_RS18965	COG0826	peptidase U32
BKP64_RS18980	COG1309	transcriptional regulator