locus-tag	class	description
FIU96_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FIU96_RS00015	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FIU96_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FIU96_RS00040	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FIU96_RS00045	COG1132	(ABC) transporter
FIU96_RS00050	COG5265	(ABC) transporter
FIU96_RS00055	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FIU96_RS00060	COG1074	ATP-dependent DNA helicase activity
FIU96_RS00065	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FIU96_RS00110	COG3040	lipid binding
FIU96_RS00135	COG0751	glycine-tRNA ligase activity
FIU96_RS00140	COG0752	glycyl-tRNA synthetase alpha subunit
FIU96_RS00145	COG0569	domain protein
FIU96_RS00150	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FIU96_RS00150	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FIU96_RS00155	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FIU96_RS00160	COG0242	peptide deformylase activity
FIU96_RS00170	COG0758	DNA mediated transformation
FIU96_RS00175	COG0009	L-threonylcarbamoyladenylate synthase
FIU96_RS00180	COG0408	coproporphyrinogen oxidase activity
FIU96_RS00185	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FIU96_RS00190	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FIU96_RS00215	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
FIU96_RS00220	COG3416	Protein conserved in bacteria
FIU96_RS00220	COG2943	transferase activity, transferring hexosyl groups
FIU96_RS00225	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FIU96_RS00230	COG0339	signal peptide processing
FIU96_RS00240	COG3328	transposase activity
FIU96_RS00245	COG2056	Na+-H+ antiporter family
FIU96_RS00255	COG3706	GGDEF domain
FIU96_RS00255	COG2203	Gaf domain
FIU96_RS00255	COG4251	negative regulation of phosphorylation
FIU96_RS00255	COG5001	Diguanylate cyclase
FIU96_RS00270	COG0534	Mate efflux family protein
FIU96_RS00275	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FIU96_RS00280	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FIU96_RS00285	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
FIU96_RS00315	COG0109	protoheme IX farnesyltransferase activity
FIU96_RS00320	COG1999	signal sequence binding
FIU96_RS00325	COG0477	Major facilitator Superfamily
FIU96_RS00330	COG1643	Atp-dependent helicase
FIU96_RS00335	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
FIU96_RS00345	COG0189	ligase activity
FIU96_RS00365	COG1917	Cupin 2, conserved barrel domain protein
FIU96_RS00370	COG1160	GTP binding
FIU96_RS00385	COG0657	acetylesterase activity
FIU96_RS00400	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FIU96_RS00410	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FIU96_RS00415	COG1028	Short-chain dehydrogenase reductase Sdr
FIU96_RS00420	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FIU96_RS00430	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FIU96_RS00450	COG3706	GGDEF domain
FIU96_RS00455	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FIU96_RS00500	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FIU96_RS00505	COG0602	queuosine metabolic process
FIU96_RS00530	COG0477	Major facilitator Superfamily
FIU96_RS00540	COG2814	Major facilitator Superfamily
FIU96_RS00545	COG2119	membrane
FIU96_RS00550	COG1388	LysM domain
FIU96_RS00550	COG1376	ErfK ybiS ycfS ynhG family protein
FIU96_RS00560	COG1030	water channel activity
FIU96_RS00565	COG0330	HflC and HflK could
FIU96_RS00590	COG1252	NADH dehydrogenase
FIU96_RS00595	COG1881	PFAM PEBP family protein
FIU96_RS00690	COG5001	Diguanylate cyclase
FIU96_RS00690	COG3300	MHYT domain
FIU96_RS00750	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FIU96_RS00755	COG0527	aspartate kinase activity
FIU96_RS00760	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FIU96_RS00775	COG2818	Glycosylase
FIU96_RS00780	COG2091	lysine biosynthetic process via aminoadipic acid
FIU96_RS00785	COG0259	pyridoxamine-phosphate oxidase activity
FIU96_RS00810	COG0121	glutamine amidotransferase
FIU96_RS00830	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FIU96_RS00835	COG2814	Major facilitator Superfamily
FIU96_RS00850	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FIU96_RS00850	COG2146	nitrite reductase [NAD(P)H] activity
FIU96_RS00855	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FIU96_RS00860	COG3707	response regulator
FIU96_RS00865	COG1116	anion transmembrane transporter activity
FIU96_RS00870	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FIU96_RS00875	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FIU96_RS00875	COG1116	anion transmembrane transporter activity
FIU96_RS00880	COG0243	molybdopterin cofactor binding
FIU96_RS00925	COG5001	Diguanylate cyclase
FIU96_RS00925	COG3447	MASE1 domain protein
FIU96_RS00925	COG5002	protein histidine kinase activity
FIU96_RS00965	COG1595	DNA-templated transcription, initiation
FIU96_RS00985	COG2011	ABC-type metal ion transport system permease component
FIU96_RS00990	COG1464	Belongs to the NlpA lipoprotein family
FIU96_RS00995	COG0450	alkyl hydroperoxide reductase
FIU96_RS01000	COG1115	amino acid carrier protein
FIU96_RS01025	COG0534	Mate efflux family protein
FIU96_RS01035	COG0840	transmembrane signaling receptor activity
FIU96_RS01040	COG0733	neurotransmitter:sodium symporter activity
FIU96_RS01070	COG0406	alpha-ribazole phosphatase activity
FIU96_RS01075	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FIU96_RS01090	COG4206	TonB-dependent receptor
FIU96_RS01095	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FIU96_RS01100	COG4139	cobalamin transport
FIU96_RS01105	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FIU96_RS01110	COG1797	cobyrinic acid a,c-diamide synthase activity
FIU96_RS01120	COG1492	cobalamin metabolic process
FIU96_RS01125	COG0778	Nitroreductase
FIU96_RS01135	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FIU96_RS01180	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FIU96_RS01205	COG4181	ATPase activity
FIU96_RS01225	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FIU96_RS01230	COG3339	Conserved Protein
FIU96_RS01240	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FIU96_RS01240	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FIU96_RS01250	COG0415	Belongs to the DNA photolyase family
FIU96_RS01255	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FIU96_RS01280	COG3909	cytochrome
FIU96_RS01285	COG2050	protein possibly involved in aromatic compounds catabolism
FIU96_RS01330	COG3012	SEC-C Motif Domain Protein
FIU96_RS01335	COG2962	Rard protein
FIU96_RS01345	COG0583	DNA-binding transcription factor activity
FIU96_RS01360	COG0840	transmembrane signaling receptor activity
FIU96_RS01365	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FIU96_RS01370	COG3842	ATPase activity
FIU96_RS01380	COG1177	transmembrane transport
FIU96_RS01385	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FIU96_RS01395	COG1115	amino acid carrier protein
FIU96_RS01400	COG0589	response to stress
FIU96_RS01405	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FIU96_RS01410	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FIU96_RS01415	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FIU96_RS01435	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FIU96_RS01440	COG0737	Belongs to the 5'-nucleotidase family
FIU96_RS01450	COG0668	transmembrane transport
FIU96_RS01465	COG1620	l-lactate permease
FIU96_RS01470	COG0247	lactate metabolic process
FIU96_RS01495	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FIU96_RS01500	COG0579	oxidoreductase
FIU96_RS01540	COG0450	alkyl hydroperoxide reductase
FIU96_RS01560	COG0739	heme binding
FIU96_RS01570	COG0633	Ferredoxin
FIU96_RS01585	COG2864	formate dehydrogenase
FIU96_RS01590	COG0437	4 iron, 4 sulfur cluster binding
FIU96_RS01620	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
FIU96_RS01620	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FIU96_RS01625	COG0489	protein tyrosine kinase activity
FIU96_RS01640	COG0303	'Molybdopterin
FIU96_RS01645	COG1763	Mo-molybdopterin cofactor biosynthetic process
FIU96_RS01650	COG0746	molybdenum cofactor guanylyltransferase activity
FIU96_RS01655	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FIU96_RS01665	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FIU96_RS01720	COG4681	YaeQ
FIU96_RS01730	COG1346	cytolysis
FIU96_RS01745	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FIU96_RS01785	COG2183	response to ionizing radiation
FIU96_RS01790	COG2918	glutathione biosynthetic process
FIU96_RS01805	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FIU96_RS01830	COG0488	(ABC) transporter
FIU96_RS01835	COG0248	Ppx GppA phosphatase
FIU96_RS01845	COG0314	molybdopterin synthase activity
FIU96_RS01850	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FIU96_RS01855	COG0303	'Molybdopterin
FIU96_RS01860	COG0521	Mo-molybdopterin cofactor biosynthetic process
FIU96_RS01870	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FIU96_RS01885	COG2959	enzyme of heme biosynthesis
FIU96_RS01895	COG0181	hydroxymethylbilane synthase activity
FIU96_RS01905	COG3275	phosphorelay sensor kinase activity
FIU96_RS01910	COG0165	Argininosuccinate lyase
FIU96_RS01935	COG5002	protein histidine kinase activity
FIU96_RS01935	COG5001	Diguanylate cyclase
FIU96_RS01940	COG3072	Adenylate cyclase
FIU96_RS01950	COG0019	diaminopimelate decarboxylase activity
FIU96_RS01955	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FIU96_RS01965	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FIU96_RS01995	COG1752	Esterase of the alpha-beta hydrolase superfamily
FIU96_RS02015	COG0596	Alpha beta hydrolase
FIU96_RS02030	COG0604	alcohol dehydrogenase
FIU96_RS02030	COG3321	synthase
FIU96_RS02035	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FIU96_RS02040	COG1960	acyl-CoA dehydrogenase activity
FIU96_RS02060	COG1595	DNA-templated transcription, initiation
FIU96_RS02070	COG1166	arginine decarboxylase activity
FIU96_RS02075	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FIU96_RS02085	COG0004	ammonium transporteR
FIU96_RS02090	COG0347	Belongs to the P(II) protein family
FIU96_RS02095	COG2960	long-chain fatty acid transporting porin activity
FIU96_RS02100	COG0606	chelatase, subunit chli
FIU96_RS02105	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FIU96_RS02115	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FIU96_RS02130	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FIU96_RS02130	COG2813	Specifically methylates the guanine in position
FIU96_RS02135	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FIU96_RS02140	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FIU96_RS02170	COG2067	long-chain fatty acid transport protein
FIU96_RS02205	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FIU96_RS02215	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FIU96_RS02220	COG1561	YicC-like family, N-terminal region
FIU96_RS02225	COG0589	response to stress
FIU96_RS02230	COG0194	GDP metabolic process
FIU96_RS02235	COG1758	RNA polymerase activity
FIU96_RS02240	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FIU96_RS02255	COG0583	DNA-binding transcription factor activity
FIU96_RS02260	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FIU96_RS02275	COG3383	formate dehydrogenase (NAD+) activity
FIU96_RS02345	COG0358	DNA primase activity
FIU96_RS02350	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FIU96_RS02355	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FIU96_RS02360	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FIU96_RS02365	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FIU96_RS02370	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FIU96_RS02370	COG0302	gtp cyclohydrolase
FIU96_RS02375	COG0166	Belongs to the GPI family
FIU96_RS02380	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FIU96_RS02385	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FIU96_RS02390	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FIU96_RS02395	COG0617	tRNA 3'-terminal CCA addition
FIU96_RS02410	COG5002	protein histidine kinase activity
FIU96_RS02425	COG1489	DNA binding
FIU96_RS02445	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FIU96_RS02480	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FIU96_RS02485	COG0352	thiamine-phosphate diphosphorylase activity
FIU96_RS02490	COG0351	phosphomethylpyrimidine kinase
FIU96_RS02490	COG0352	thiamine-phosphate diphosphorylase activity
FIU96_RS02490	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FIU96_RS02495	COG1981	membrane
FIU96_RS02505	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FIU96_RS02520	COG0316	Belongs to the HesB IscA family
FIU96_RS02525	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FIU96_RS02530	COG0739	heme binding
FIU96_RS02535	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FIU96_RS02595	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FIU96_RS02625	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FIU96_RS02645	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FIU96_RS02650	COG0081	regulation of translation
FIU96_RS02655	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FIU96_RS02660	COG0222	ribosome binding
FIU96_RS02665	COG0085	RNA polymerase activity
FIU96_RS02670	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FIU96_RS02675	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FIU96_RS02680	COG0049	tRNA binding
FIU96_RS02685	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FIU96_RS02690	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FIU96_RS02695	COG0051	transcription antitermination factor activity, RNA binding
FIU96_RS02700	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FIU96_RS02705	COG0088	Forms part of the polypeptide exit tunnel
FIU96_RS02710	COG0089	rRNA binding
FIU96_RS02715	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FIU96_RS02720	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FIU96_RS02725	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FIU96_RS02730	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FIU96_RS02735	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FIU96_RS02740	COG0255	Belongs to the universal ribosomal protein uL29 family
FIU96_RS02745	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FIU96_RS02750	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FIU96_RS02755	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FIU96_RS02760	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FIU96_RS02765	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FIU96_RS02770	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FIU96_RS02775	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FIU96_RS02780	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FIU96_RS02785	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FIU96_RS02790	COG1841	ribosomal large subunit assembly
FIU96_RS02795	COG0200	Binds to the 23S rRNA
FIU96_RS02805	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FIU96_RS02810	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FIU96_RS02815	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FIU96_RS02820	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FIU96_RS02825	COG0202	RNA polymerase activity
FIU96_RS02830	COG0203	ribosomal protein L17
FIU96_RS02840	COG2814	Major facilitator Superfamily
FIU96_RS02880	COG0811	peptide transport
FIU96_RS02900	COG4772	TonB-dependent receptor
FIU96_RS02910	COG2204	response regulator
FIU96_RS02915	COG3852	Histidine kinase
FIU96_RS02930	COG1217	gtp-binding protein TYPA
FIU96_RS02940	COG1490	D-aminoacyl-tRNA deacylase activity
FIU96_RS02960	COG2239	Acts as a magnesium transporter
FIU96_RS02970	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FIU96_RS03010	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FIU96_RS03015	COG0859	PFAM glycosyl transferase family 9
FIU96_RS03020	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FIU96_RS03020	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FIU96_RS03025	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FIU96_RS03030	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FIU96_RS03035	COG0859	PFAM glycosyl transferase family 9
FIU96_RS03050	COG0438	transferase activity, transferring glycosyl groups
FIU96_RS03055	COG1560	Kdo2-lipid A biosynthetic process
FIU96_RS03065	COG0463	Glycosyl transferase, family 2
FIU96_RS03070	COG0438	transferase activity, transferring glycosyl groups
FIU96_RS03085	COG1560	Kdo2-lipid A biosynthetic process
FIU96_RS03090	COG1519	Transferase
FIU96_RS03095	COG1538	Outer membrane efflux protein
FIU96_RS03105	COG0494	nUDIX hydrolase
FIU96_RS03110	COG3151	Protein conserved in bacteria
FIU96_RS03115	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FIU96_RS03125	COG3550	peptidyl-serine autophosphorylation
FIU96_RS03130	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FIU96_RS03135	COG0583	DNA-binding transcription factor activity
FIU96_RS03140	COG0509	glycine decarboxylation via glycine cleavage system
FIU96_RS03145	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FIU96_RS03155	COG0494	nUDIX hydrolase
FIU96_RS03170	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FIU96_RS03175	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FIU96_RS03185	COG0018	arginyl-trna synthetase
FIU96_RS03195	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FIU96_RS03200	COG0254	rRNA binding
FIU96_RS03205	COG0281	malic enzyme
FIU96_RS03240	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FIU96_RS03255	COG0070	glutamate synthase
FIU96_RS03255	COG0067	glutamate synthase
FIU96_RS03255	COG0069	glutamate synthase activity
FIU96_RS03260	COG0493	'glutamate synthase
FIU96_RS03265	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FIU96_RS03280	COG0488	(ABC) transporter
FIU96_RS03285	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FIU96_RS03290	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FIU96_RS03295	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FIU96_RS03295	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FIU96_RS03305	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FIU96_RS03310	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FIU96_RS03320	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FIU96_RS03340	COG0583	DNA-binding transcription factor activity
FIU96_RS03345	COG0435	Glutathione S-transferase
FIU96_RS03350	COG0142	geranyltranstransferase activity
FIU96_RS03355	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FIU96_RS03360	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FIU96_RS03365	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FIU96_RS03370	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FIU96_RS03375	COG0268	Binds directly to 16S ribosomal RNA
FIU96_RS03385	COG0196	riboflavin kinase activity
FIU96_RS03390	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FIU96_RS03400	COG1047	Peptidyl-prolyl cis-trans
FIU96_RS03405	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FIU96_RS03475	COG1496	oxidoreductase activity
FIU96_RS03490	COG0028	Belongs to the TPP enzyme family
FIU96_RS03495	COG0440	acetolactate synthase activity
FIU96_RS03500	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FIU96_RS03505	COG1183	phosphatidylcholine synthase activity
FIU96_RS03510	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FIU96_RS03545	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FIU96_RS03560	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FIU96_RS03565	COG0084	hydrolase, TatD family'
FIU96_RS03570	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FIU96_RS03575	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FIU96_RS03580	COG0723	plastoquinol--plastocyanin reductase activity
FIU96_RS03585	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FIU96_RS03590	COG2857	Cytochrome c1
FIU96_RS03595	COG0625	glutathione transferase activity
FIU96_RS03600	COG2969	positive regulation of protein catabolic process
FIU96_RS03605	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FIU96_RS03610	COG0792	nuclease activity
FIU96_RS03630	COG2001	Belongs to the MraZ family
FIU96_RS03635	COG0275	rRNA processing
FIU96_RS03640	COG3116	cell division
FIU96_RS03650	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FIU96_RS03655	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FIU96_RS03660	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FIU96_RS03665	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FIU96_RS03670	COG0772	Belongs to the SEDS family
FIU96_RS03675	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FIU96_RS03680	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FIU96_RS03685	COG1181	Belongs to the D-alanine--D-alanine ligase family
FIU96_RS03710	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FIU96_RS03720	COG0739	heme binding
FIU96_RS03725	COG0653	protein targeting
FIU96_RS03730	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FIU96_RS03735	COG0494	nUDIX hydrolase
FIU96_RS03740	COG0315	cyclic pyranopterin monophosphate synthase activity
FIU96_RS03745	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FIU96_RS03750	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FIU96_RS03755	COG0142	geranyltranstransferase activity
FIU96_RS03770	COG0730	response to heat
FIU96_RS03775	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FIU96_RS03780	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FIU96_RS03800	COG0596	Alpha beta hydrolase
FIU96_RS03815	COG0628	permease
FIU96_RS03825	COG0129	dihydroxy-acid dehydratase activity
FIU96_RS03840	COG0586	Pfam SNARE associated Golgi protein
FIU96_RS03855	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FIU96_RS03860	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FIU96_RS03870	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FIU96_RS03875	COG0768	penicillin binding
FIU96_RS03880	COG0772	Belongs to the SEDS family
FIU96_RS03885	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FIU96_RS03890	COG1686	Belongs to the peptidase S11 family
FIU96_RS03895	COG2921	Belongs to the UPF0250 family
FIU96_RS03900	COG0321	lipoyl(octanoyl) transferase activity
FIU96_RS03905	COG3706	GGDEF domain
FIU96_RS03910	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FIU96_RS03915	COG1238	metal cluster binding
FIU96_RS03920	COG0840	transmembrane signaling receptor activity
FIU96_RS03930	COG0205	6-phosphofructokinase activity
FIU96_RS03935	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FIU96_RS03945	COG1960	acyl-CoA dehydrogenase activity
FIU96_RS03960	COG0557	exoribonuclease II activity
FIU96_RS03965	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FIU96_RS03970	COG0360	Binds together with S18 to 16S ribosomal RNA
FIU96_RS03975	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FIU96_RS03985	COG0359	binds to the 23S rRNA
FIU96_RS03990	COG0305	Participates in initiation and elongation during chromosome replication
FIU96_RS03995	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FIU96_RS04010	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FIU96_RS04015	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FIU96_RS04035	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FIU96_RS04040	COG2873	o-acetylhomoserine
FIU96_RS04055	COG0012	GTP binding
FIU96_RS04060	COG0193	aminoacyl-tRNA hydrolase activity
FIU96_RS04065	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FIU96_RS04070	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FIU96_RS04080	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FIU96_RS04085	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
FIU96_RS04095	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FIU96_RS04100	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FIU96_RS04130	COG4067	protein conserved in archaea
FIU96_RS04130	COG0189	ligase activity
FIU96_RS04135	COG0189	ligase activity
FIU96_RS04170	COG4191	Histidine kinase
FIU96_RS04175	COG2204	response regulator
FIU96_RS04185	COG0028	Belongs to the TPP enzyme family
FIU96_RS04210	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FIU96_RS04215	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
FIU96_RS04230	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FIU96_RS04235	COG2894	cell division
FIU96_RS04240	COG0850	regulation of cytokinetic process
FIU96_RS04255	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FIU96_RS04280	COG0667	Aldo Keto reductase
FIU96_RS04290	COG0427	acetyl-CoA hydrolase
FIU96_RS04295	COG1047	Peptidyl-prolyl cis-trans
FIU96_RS04310	COG0745	RESPONSE REGULATOR receiver
FIU96_RS04315	COG2205	protein histidine kinase activity
FIU96_RS04320	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FIU96_RS04325	COG3842	ATPase activity
FIU96_RS04330	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FIU96_RS04335	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FIU96_RS04350	COG4536	flavin adenine dinucleotide binding
FIU96_RS04360	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FIU96_RS04365	COG0228	four-way junction DNA binding
FIU96_RS04370	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FIU96_RS04375	COG0336	Belongs to the RNA methyltransferase TrmD family
FIU96_RS04380	COG0335	large ribosomal subunit rRNA binding
FIU96_RS04390	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FIU96_RS04405	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FIU96_RS04415	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FIU96_RS04420	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FIU96_RS04470	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FIU96_RS04480	COG0481	GTPase activity
FIU96_RS04485	COG0681	Belongs to the peptidase S26 family
FIU96_RS04495	COG0571	ribonuclease III activity
FIU96_RS04500	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FIU96_RS04505	COG1381	Involved in DNA repair and RecF pathway recombination
FIU96_RS04515	COG0784	Response regulator, receiver
FIU96_RS04515	COG2205	protein histidine kinase activity
FIU96_RS04515	COG5002	protein histidine kinase activity
FIU96_RS04525	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FIU96_RS04530	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FIU96_RS04535	COG3956	TIGRFAM MazG family protein
FIU96_RS04550	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FIU96_RS04560	COG0563	adenylate kinase activity
FIU96_RS04565	COG1214	PFAM Peptidase M22, glycoprotease
FIU96_RS04575	COG0742	ribosomal rna small subunit methyltransferase
FIU96_RS04580	COG2937	Belongs to the GPAT DAPAT family
FIU96_RS04585	COG2816	NAD+ diphosphatase activity
FIU96_RS04590	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FIU96_RS04610	COG3852	Histidine kinase
FIU96_RS04625	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FIU96_RS04645	COG0436	Aminotransferase
FIU96_RS04660	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FIU96_RS04665	COG0473	3-isopropylmalate dehydrogenase activity
FIU96_RS04670	COG2200	EAL domain
FIU96_RS04685	COG1960	acyl-CoA dehydrogenase activity
FIU96_RS04705	COG1028	Short-chain dehydrogenase reductase Sdr
FIU96_RS04720	COG4459	periplasmic nitrate reductase
FIU96_RS04745	COG3005	denitrification pathway
FIU96_RS04765	COG2133	pyrroloquinoline quinone binding
FIU96_RS04770	COG4774	siderophore transport
FIU96_RS04780	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FIU96_RS04785	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FIU96_RS04790	COG1120	ATPase activity
FIU96_RS04795	COG1132	(ABC) transporter
FIU96_RS04800	COG1671	Belongs to the UPF0178 family
FIU96_RS04810	COG2824	Alkylphosphonate utilization operon protein PhnA
FIU96_RS04845	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FIU96_RS04855	COG2015	COG2015, Alkyl sulfatase and related hydrolases
FIU96_RS04870	COG1595	DNA-templated transcription, initiation
FIU96_RS04875	COG3795	YCII-related domain
FIU96_RS04880	COG5507	3-demethylubiquinone-9 3-methyltransferase
FIU96_RS04885	COG1944	ATP diphosphatase activity
FIU96_RS04895	COG3228	Belongs to the MtfA family
FIU96_RS04910	COG1234	tRNA 3'-trailer cleavage
FIU96_RS04930	COG0583	DNA-binding transcription factor activity
FIU96_RS04960	COG0523	cobalamin synthesis protein
FIU96_RS04985	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FIU96_RS05000	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FIU96_RS05005	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FIU96_RS05005	COG0519	Catalyzes the synthesis of GMP from XMP
FIU96_RS05010	COG0217	transcriptional regulatory protein
FIU96_RS05030	COG3501	Rhs element vgr protein
FIU96_RS05050	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FIU96_RS05075	COG0628	permease
FIU96_RS05085	COG3938	Belongs to the proline racemase family
FIU96_RS05090	COG2226	methyltransferase
FIU96_RS05095	COG5662	AntiSigma factor
FIU96_RS05100	COG1595	DNA-templated transcription, initiation
FIU96_RS05115	COG1177	transmembrane transport
FIU96_RS05120	COG1176	ABC-type spermidine putrescine transport system, permease component I
FIU96_RS05125	COG3842	ATPase activity
FIU96_RS05150	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FIU96_RS05160	COG2366	antibiotic biosynthetic process
FIU96_RS05210	COG1024	Enoyl-CoA hydratase
FIU96_RS05255	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FIU96_RS05285	COG1172	Belongs to the binding-protein-dependent transport system permease family
FIU96_RS05290	COG2764	glyoxalase bleomycin resistance protein dioxygenase
FIU96_RS05295	COG2031	fatty acid transporter
FIU96_RS05305	COG5001	Diguanylate cyclase
FIU96_RS05305	COG3300	MHYT domain
FIU96_RS05315	COG3384	dioxygenase
FIU96_RS05320	COG2259	Doxx family
FIU96_RS05325	COG0583	DNA-binding transcription factor activity
FIU96_RS05335	COG1794	racemase activity, acting on amino acids and derivatives
FIU96_RS05360	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FIU96_RS05370	COG0318	PFAM AMP-dependent synthetase and ligase
FIU96_RS05385	COG4770	biotin carboxylase activity
FIU96_RS05395	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FIU96_RS05400	COG1960	acyl-CoA dehydrogenase activity
FIU96_RS05415	COG1960	acyl-CoA dehydrogenase activity
FIU96_RS05420	COG0183	Belongs to the thiolase family
FIU96_RS05425	COG0733	neurotransmitter:sodium symporter activity
FIU96_RS05435	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FIU96_RS05440	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FIU96_RS05445	COG1116	anion transmembrane transporter activity
FIU96_RS05450	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
FIU96_RS05455	COG0129	dihydroxy-acid dehydratase activity
FIU96_RS05490	COG3706	GGDEF domain
FIU96_RS05490	COG2203	Gaf domain
FIU96_RS05490	COG4251	negative regulation of phosphorylation
FIU96_RS05490	COG5001	Diguanylate cyclase
FIU96_RS05510	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FIU96_RS05515	COG3145	DNA-N1-methyladenine dioxygenase activity
FIU96_RS05525	COG0659	secondary active sulfate transmembrane transporter activity
FIU96_RS05530	COG0589	response to stress
FIU96_RS05535	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FIU96_RS05540	COG2081	HI0933 family
FIU96_RS05555	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FIU96_RS05560	COG4566	intracellular signal transduction
FIU96_RS05565	COG4191	Histidine kinase
FIU96_RS05570	COG0318	PFAM AMP-dependent synthetase and ligase
FIU96_RS05590	COG1307	EDD domain protein, DegV family
FIU96_RS05600	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FIU96_RS05605	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FIU96_RS05610	COG1546	Belongs to the CinA family
FIU96_RS05615	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FIU96_RS05630	COG1067	ATP-dependent peptidase activity
FIU96_RS05635	COG4566	intracellular signal transduction
FIU96_RS05640	COG4191	Histidine kinase
FIU96_RS05665	COG1902	pentaerythritol trinitrate reductase activity
FIU96_RS05665	COG0446	pyridine nucleotide-disulphide oxidoreductase
FIU96_RS05675	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FIU96_RS05680	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FIU96_RS05685	COG0705	Rhomboid family
FIU96_RS05690	COG3139	Protein of unknown function (DUF1315)
FIU96_RS05700	COG0308	aminopeptidase N
FIU96_RS05710	COG4447	cellulose binding
FIU96_RS05715	COG2409	Drug exporters of the RND superfamily
FIU96_RS05720	COG2358	TRAP transporter, solute receptor (TAXI family
FIU96_RS05730	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FIU96_RS05735	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FIU96_RS05740	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FIU96_RS05745	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FIU96_RS05750	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FIU96_RS05755	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FIU96_RS05755	COG0072	phenylalanine-tRNA ligase activity
FIU96_RS05760	COG0776	regulation of translation
FIU96_RS05780	COG1929	Belongs to the glycerate kinase type-1 family
FIU96_RS05785	COG1522	sequence-specific DNA binding
FIU96_RS05790	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FIU96_RS05790	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FIU96_RS05790	COG0506	proline dehydrogenase activity
FIU96_RS05815	COG4983	Phage plasmid primase, P4 family domain protein
FIU96_RS05860	COG3328	transposase activity
FIU96_RS05870	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FIU96_RS05895	COG0210	DNA helicase
FIU96_RS05930	COG3311	Transcriptional regulator
FIU96_RS05935	COG1999	signal sequence binding
FIU96_RS05945	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FIU96_RS06055	COG0785	Cytochrome C biogenesis protein
FIU96_RS06135	COG4753	response regulator
FIU96_RS06135	COG2207	Transcriptional regulator
FIU96_RS06140	COG0642	Histidine kinase
FIU96_RS06150	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FIU96_RS06190	COG4974	Belongs to the 'phage' integrase family
FIU96_RS06220	COG1028	Short-chain dehydrogenase reductase Sdr
FIU96_RS06225	COG0697	spore germination
FIU96_RS06230	COG1028	Short-chain dehydrogenase reductase Sdr
FIU96_RS06250	COG0069	glutamate synthase activity
FIU96_RS06255	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FIU96_RS06260	COG0189	ligase activity
FIU96_RS06270	COG0189	ligase activity
FIU96_RS06270	COG4067	protein conserved in archaea
FIU96_RS06280	COG1322	Protein conserved in bacteria
FIU96_RS06290	COG2207	Transcriptional regulator
FIU96_RS06295	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FIU96_RS06300	COG2267	carboxylic ester hydrolase activity
FIU96_RS06300	COG2267	carboxylic ester hydrolase activity
FIU96_RS06310	COG3695	enzyme binding
FIU96_RS06315	COG1028	Short-chain dehydrogenase reductase Sdr
FIU96_RS06325	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FIU96_RS06330	COG0459	protein refolding
FIU96_RS06350	COG0501	Belongs to the peptidase M48B family
FIU96_RS06355	COG1704	LemA family
FIU96_RS06360	COG2203	Gaf domain
FIU96_RS06360	COG4251	negative regulation of phosphorylation
FIU96_RS06360	COG5001	Diguanylate cyclase
FIU96_RS06360	COG3706	GGDEF domain
FIU96_RS06375	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FIU96_RS06410	COG1028	Short-chain dehydrogenase reductase Sdr
FIU96_RS06415	COG0183	Belongs to the thiolase family
FIU96_RS06425	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
FIU96_RS06430	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FIU96_RS06440	COG1960	acyl-CoA dehydrogenase activity
FIU96_RS06445	COG1960	acyl-CoA dehydrogenase activity
FIU96_RS06450	COG0729	surface antigen
FIU96_RS06455	COG2911	Protein conserved in bacteria
FIU96_RS06465	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FIU96_RS06475	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FIU96_RS06520	COG1677	Flagellar hook-basal body complex protein FliE
FIU96_RS06615	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FIU96_RS06650	COG0643	Histidine kinase
FIU96_RS06650	COG0784	Response regulator, receiver
FIU96_RS06650	COG2198	Histidine kinase
FIU96_RS06655	COG2201	protein-glutamate methylesterase activity
FIU96_RS06660	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FIU96_RS06665	COG1360	Flagellar Motor Protein
FIU96_RS06670	COG1192	Involved in chromosome partitioning
FIU96_RS06680	COG0835	chemotaxis
FIU96_RS06695	COG0714	Associated with various cellular activities
FIU96_RS06710	COG4133	protoheme IX ABC transporter activity
FIU96_RS06715	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FIU96_RS06730	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FIU96_RS06735	COG1138	Cytochrome C-type biogenesis protein
FIU96_RS06740	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FIU96_RS06760	COG2304	oxidoreductase activity
FIU96_RS06780	COG0714	Associated with various cellular activities
FIU96_RS06790	COG0288	reversible hydration of carbon dioxide
FIU96_RS06795	COG2813	Specifically methylates the guanine in position
FIU96_RS06800	COG2813	Specifically methylates the guanine in position
FIU96_RS06805	COG0307	riboflavin synthase, alpha
FIU96_RS06820	COG1376	ErfK ybiS ycfS ynhG family protein
FIU96_RS06825	COG0668	transmembrane transport
FIU96_RS06830	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FIU96_RS06840	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FIU96_RS06850	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FIU96_RS06855	COG1805	sodium ion transport
FIU96_RS06870	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FIU96_RS06875	COG2871	sodium ion transport
FIU96_RS06880	COG1477	protein flavinylation
FIU96_RS06890	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FIU96_RS06895	COG0584	glycerophosphoryl diester phosphodiesterase
FIU96_RS06900	COG1605	Chorismate mutase
FIU96_RS06900	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FIU96_RS06910	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FIU96_RS06915	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FIU96_RS07010	COG0756	dUTP diphosphatase activity
FIU96_RS07055	COG0305	Participates in initiation and elongation during chromosome replication
FIU96_RS07280	COG2226	methyltransferase
FIU96_RS07335	COG1061	Type III restriction enzyme res subunit
FIU96_RS07350	COG1803	Methylglyoxal synthase
FIU96_RS07355	COG1028	Short-chain dehydrogenase reductase Sdr
FIU96_RS07385	COG2124	cytochrome p450
FIU96_RS07390	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FIU96_RS07395	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
FIU96_RS07400	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FIU96_RS07445	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FIU96_RS07455	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FIU96_RS07470	COG2350	Protein conserved in bacteria
FIU96_RS07475	COG0613	PHP domain protein
FIU96_RS07485	COG1530	ribonuclease E activity
FIU96_RS07490	COG0564	pseudouridine synthase activity
FIU96_RS07495	COG0546	phosphoglycolate phosphatase activity
FIU96_RS07505	COG0424	maF-like protein
FIU96_RS07515	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FIU96_RS07520	COG0416	fatty acid biosynthetic process
FIU96_RS07525	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FIU96_RS07535	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FIU96_RS07540	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FIU96_RS07545	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FIU96_RS07550	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FIU96_RS07555	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FIU96_RS07565	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FIU96_RS07580	COG0583	DNA-binding transcription factor activity
FIU96_RS07595	COG0584	glycerophosphoryl diester phosphodiesterase
FIU96_RS07600	COG3119	arylsulfatase activity
FIU96_RS07605	COG2133	pyrroloquinoline quinone binding
FIU96_RS07610	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FIU96_RS07615	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FIU96_RS07620	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FIU96_RS07625	COG0215	cysteine-tRNA ligase activity
FIU96_RS07630	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FIU96_RS07635	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FIU96_RS07660	COG0544	peptidyl-prolyl cis-trans isomerase activity
FIU96_RS07665	COG0740	serine-type endopeptidase activity
FIU96_RS07670	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FIU96_RS07675	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FIU96_RS07685	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FIU96_RS07700	COG4580	involved in the transport of maltose and maltodextrins
FIU96_RS07705	COG1737	Transcriptional regulator
FIU96_RS07720	COG0800	Aldolase
FIU96_RS07740	COG0837	glucose binding
FIU96_RS07745	COG1573	uracil-dna glycosylase
FIU96_RS07755	COG0366	Alpha amylase catalytic
FIU96_RS07765	COG1175	transmembrane transport
FIU96_RS07770	COG3833	ABC-type maltose transport systems, permease component
FIU96_RS07780	COG0366	Alpha amylase catalytic
FIU96_RS07790	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FIU96_RS07805	COG1477	protein flavinylation
FIU96_RS07840	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FIU96_RS07905	COG3243	poly(R)-hydroxyalkanoic acid synthase
FIU96_RS07920	COG0471	metal ion transport
FIU96_RS07960	COG0037	tRNA processing
FIU96_RS07975	COG2217	Heavy metal translocating P-type atpase
FIU96_RS07985	COG0348	domain, Protein
FIU96_RS07990	COG2010	Cytochrome c
FIU96_RS08005	COG3278	Belongs to the heme-copper respiratory oxidase family
FIU96_RS08020	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
FIU96_RS08030	COG0425	Belongs to the sulfur carrier protein TusA family
FIU96_RS08040	COG3101	peptidyl-lysine hydroxylation
FIU96_RS08045	COG0513	Belongs to the DEAD box helicase family
FIU96_RS08050	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FIU96_RS08055	COG0501	Belongs to the peptidase M48B family
FIU96_RS08065	COG0436	Aminotransferase
FIU96_RS08070	COG0386	Belongs to the glutathione peroxidase family
FIU96_RS08075	COG1846	Transcriptional regulator
FIU96_RS08080	COG2205	protein histidine kinase activity
FIU96_RS08080	COG0784	Response regulator, receiver
FIU96_RS08080	COG5002	protein histidine kinase activity
FIU96_RS08100	COG2850	peptidyl-arginine hydroxylation
FIU96_RS08110	COG2915	High frequency lysogenization protein hflD homolog
FIU96_RS08115	COG0482	sulfurtransferase activity
FIU96_RS08130	COG1278	Cold shock
FIU96_RS08135	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FIU96_RS08140	COG0542	response to heat
FIU96_RS08150	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FIU96_RS08155	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FIU96_RS08160	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FIU96_RS08165	COG0492	ferredoxin-NADP+ reductase activity
FIU96_RS08170	COG0714	Associated with various cellular activities
FIU96_RS08175	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FIU96_RS08180	COG2957	Belongs to the agmatine deiminase family
FIU96_RS08195	COG4591	ABC-type transport system involved in lipoprotein release permease component
FIU96_RS08200	COG1136	(ABC) transporter
FIU96_RS08210	COG2333	competence protein COMEC
FIU96_RS08210	COG0658	competence protein
FIU96_RS08215	COG0811	peptide transport
FIU96_RS08220	COG0848	biopolymer transport protein
FIU96_RS08225	COG1132	(ABC) transporter
FIU96_RS08230	COG1663	tetraacyldisaccharide 4'-kinase activity
FIU96_RS08235	COG2835	tetraacyldisaccharide 4'-kinase activity
FIU96_RS08240	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FIU96_RS08245	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FIU96_RS08250	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FIU96_RS08255	COG0442	prolyl-tRNA aminoacylation
FIU96_RS08265	COG1522	sequence-specific DNA binding
FIU96_RS08270	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FIU96_RS08275	COG1278	Cold shock
FIU96_RS08285	COG1570	exodeoxyribonuclease VII activity
FIU96_RS08295	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FIU96_RS08295	COG0519	Catalyzes the synthesis of GMP from XMP
FIU96_RS08325	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FIU96_RS08330	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FIU96_RS08335	COG0632	four-way junction helicase activity
FIU96_RS08340	COG2255	four-way junction helicase activity
FIU96_RS08345	COG0824	Thioesterase
FIU96_RS08365	COG0823	Involved in the tonB-independent uptake of proteins
FIU96_RS08370	COG2885	chlorophyll binding
FIU96_RS08375	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
FIU96_RS08390	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FIU96_RS08395	COG4783	chaperone-mediated protein folding
FIU96_RS08400	COG0425	Belongs to the sulfur carrier protein TusA family
FIU96_RS08410	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FIU96_RS08415	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FIU96_RS08425	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FIU96_RS08445	COG0564	pseudouridine synthase activity
FIU96_RS08450	COG1940	carbohydrate kinase activity
FIU96_RS08485	COG1183	phosphatidylcholine synthase activity
FIU96_RS08490	COG1063	alcohol dehydrogenase
FIU96_RS08510	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FIU96_RS08510	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FIU96_RS08535	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FIU96_RS08540	COG0372	Belongs to the citrate synthase family
FIU96_RS08560	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FIU96_RS08575	COG0489	protein tyrosine kinase activity
FIU96_RS08590	COG0463	Glycosyl transferase, family 2
FIU96_RS08615	COG0438	transferase activity, transferring glycosyl groups
FIU96_RS08625	COG2843	Capsule synthesis protein
FIU96_RS08645	COG1215	transferase activity, transferring glycosyl groups
FIU96_RS08650	COG0438	transferase activity, transferring glycosyl groups
FIU96_RS08675	COG0367	asparagine synthase
FIU96_RS08680	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FIU96_RS08690	COG0463	Glycosyl transferase, family 2
FIU96_RS08695	COG1216	Glycosyl transferase, family 2
FIU96_RS08695	COG0463	Glycosyl transferase, family 2
FIU96_RS08725	COG2133	pyrroloquinoline quinone binding
FIU96_RS08725	COG5183	chlorophyll binding
FIU96_RS08735	COG2204	response regulator
FIU96_RS08740	COG4191	Histidine kinase
FIU96_RS08750	COG0204	Acyl-transferase
FIU96_RS08755	COG0676	glucose-6-phosphate 1-epimerase activity
FIU96_RS08770	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FIU96_RS08775	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FIU96_RS08780	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FIU96_RS08790	COG3100	YcgL domain-containing protein
FIU96_RS08795	COG2983	Belongs to the UPF0260 family
FIU96_RS08810	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FIU96_RS08865	COG2030	dehydratase
FIU96_RS08870	COG0318	PFAM AMP-dependent synthetase and ligase
FIU96_RS08875	COG1643	Atp-dependent helicase
FIU96_RS08890	COG2853	Lipoprotein
FIU96_RS08895	COG1752	Esterase of the alpha-beta hydrolase superfamily
FIU96_RS08900	COG3267	Type II secretory pathway component ExeA
FIU96_RS08900	COG3409	Peptidoglycan-binding domain 1 protein
FIU96_RS08910	COG1199	ATP-dependent helicase activity
FIU96_RS08915	COG2909	trisaccharide binding
FIU96_RS08975	COG0596	Alpha beta hydrolase
FIU96_RS08995	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FIU96_RS09015	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FIU96_RS09020	COG0066	3-isopropylmalate dehydratase activity
FIU96_RS09025	COG0473	3-isopropylmalate dehydrogenase activity
FIU96_RS09040	COG0101	tRNA pseudouridine synthase activity
FIU96_RS09045	COG0135	phosphoribosylanthranilate isomerase activity
FIU96_RS09055	COG0159	tryptophan synthase activity
FIU96_RS09060	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FIU96_RS09065	COG0285	dihydrofolate synthase activity
FIU96_RS09075	COG1286	toxin biosynthetic process
FIU96_RS09095	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FIU96_RS09100	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FIU96_RS09105	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FIU96_RS09110	COG1648	precorrin-2 dehydrogenase activity
FIU96_RS09110	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FIU96_RS09115	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FIU96_RS09135	COG4172	Belongs to the ABC transporter superfamily
FIU96_RS09140	COG4239	(ABC) transporter, permease
FIU96_RS09145	COG4174	ABC transporter (Permease)
FIU96_RS09150	COG4166	transmembrane transport
FIU96_RS09155	COG0741	lytic transglycosylase activity
FIU96_RS09155	COG1388	LysM domain
FIU96_RS09160	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FIU96_RS09170	COG0328	RNA-DNA hybrid ribonuclease activity
FIU96_RS09175	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FIU96_RS09190	COG0616	signal peptide processing
FIU96_RS09215	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FIU96_RS09215	COG0316	Belongs to the HesB IscA family
FIU96_RS09230	COG2920	part of a sulfur-relay system
FIU96_RS09275	COG3039	Transposase
FIU96_RS09295	COG1984	allophanate hydrolase subunit 2
FIU96_RS09300	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FIU96_RS09305	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FIU96_RS09310	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FIU96_RS09315	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FIU96_RS09315	COG3453	Protein conserved in bacteria
FIU96_RS09340	COG0708	Exodeoxyribonuclease III
FIU96_RS09355	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FIU96_RS09370	COG4221	oxidoreductase activity
FIU96_RS09385	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
FIU96_RS09395	COG2204	response regulator
FIU96_RS09405	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FIU96_RS09460	COG3268	Saccharopine dehydrogenase
FIU96_RS09465	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FIU96_RS09470	COG4988	ABC transporter
FIU96_RS09475	COG1294	oxidase, subunit
FIU96_RS09480	COG1271	oxidase subunit
FIU96_RS09500	COG1024	Enoyl-CoA hydratase
FIU96_RS09510	COG0842	Transport permease protein
FIU96_RS09515	COG1131	(ABC) transporter
FIU96_RS09535	COG3639	organic phosphonate transmembrane transporter activity
FIU96_RS09540	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FIU96_RS09545	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
FIU96_RS09550	COG0438	transferase activity, transferring glycosyl groups
FIU96_RS09555	COG0709	Synthesizes selenophosphate from selenide and ATP
FIU96_RS09560	COG3743	rRNA binding
FIU96_RS09560	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FIU96_RS09570	COG3153	acetyltransferase
FIU96_RS09570	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FIU96_RS09590	COG0514	ATP-dependent DNA helicase (RecQ)
FIU96_RS09605	COG0297	glycogen (starch) synthase activity
FIU96_RS09610	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FIU96_RS09615	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FIU96_RS09635	COG1028	Short-chain dehydrogenase reductase Sdr
FIU96_RS09645	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FIU96_RS09660	COG2205	protein histidine kinase activity
FIU96_RS09665	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FIU96_RS09670	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FIU96_RS09675	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FIU96_RS09685	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FIU96_RS09690	COG0569	domain protein
FIU96_RS09700	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FIU96_RS09730	COG0583	DNA-binding transcription factor activity
FIU96_RS09735	COG0625	glutathione transferase activity
FIU96_RS09750	COG2207	Transcriptional regulator
FIU96_RS09755	COG4221	oxidoreductase activity
FIU96_RS09770	COG0024	Methionine aminopeptidase
FIU96_RS09835	COG4977	sequence-specific DNA binding
FIU96_RS09845	COG2015	COG2015, Alkyl sulfatase and related hydrolases
FIU96_RS09850	COG0583	DNA-binding transcription factor activity
FIU96_RS09860	COG1335	isochorismatase
FIU96_RS09870	COG1741	Belongs to the pirin family
FIU96_RS09880	COG0579	oxidoreductase
FIU96_RS09895	COG1064	alcohol dehydrogenase
FIU96_RS09900	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FIU96_RS09910	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FIU96_RS09915	COG4208	sulfate ABC transporter
FIU96_RS09920	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FIU96_RS09925	COG3002	Belongs to the UPF0753 family
FIU96_RS09930	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FIU96_RS09935	COG0583	DNA-binding transcription factor activity
FIU96_RS09945	COG2186	Transcriptional regulator
FIU96_RS10040	COG0277	FAD linked oxidase domain protein
FIU96_RS10050	COG1070	Carbohydrate kinase
FIU96_RS10070	COG0577	efflux transmembrane transporter activity
FIU96_RS10070	COG1136	(ABC) transporter
FIU96_RS10075	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FIU96_RS10085	COG1278	Cold shock
FIU96_RS10095	COG4221	oxidoreductase activity
FIU96_RS10100	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FIU96_RS10135	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FIU96_RS10140	COG1127	ABC transporter
FIU96_RS10180	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FIU96_RS10185	COG1687	branched-chain amino acid
FIU96_RS10220	COG0583	DNA-binding transcription factor activity
FIU96_RS10225	COG2814	Major facilitator Superfamily
FIU96_RS10230	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FIU96_RS10235	COG0784	Response regulator, receiver
FIU96_RS10235	COG0835	chemotaxis
FIU96_RS10245	COG2747	anti-sigma28 factor FlgM
FIU96_RS10265	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FIU96_RS10265	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FIU96_RS10280	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FIU96_RS10285	COG3115	cell septum assembly
FIU96_RS10295	COG2186	Transcriptional regulator
FIU96_RS10310	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FIU96_RS10320	COG0180	Tryptophanyl-tRNA synthetase
FIU96_RS10330	COG0045	succinate-CoA ligase (ADP-forming) activity
FIU96_RS10355	COG1053	succinate dehydrogenase
FIU96_RS10360	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FIU96_RS10375	COG2084	Dehydrogenase
FIU96_RS10385	COG0183	Belongs to the thiolase family
FIU96_RS10390	COG1250	3-hydroxyacyl-CoA dehydrogenase
FIU96_RS10390	COG1024	Enoyl-CoA hydratase
FIU96_RS10400	COG0589	response to stress
FIU96_RS10410	COG0488	(ABC) transporter
FIU96_RS10415	COG3217	Mosc domain protein beta barrel domain protein
FIU96_RS10415	COG0633	Ferredoxin
FIU96_RS10435	COG1090	epimerase
FIU96_RS10450	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FIU96_RS10460	COG1160	GTP binding
FIU96_RS10465	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FIU96_RS10475	COG0124	histidyl-tRNA synthetase
FIU96_RS10480	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FIU96_RS10495	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FIU96_RS10500	COG0105	UTP biosynthetic process
FIU96_RS10540	COG1862	Preprotein translocase
FIU96_RS10545	COG0343	queuine tRNA-ribosyltransferase activity
FIU96_RS10550	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FIU96_RS10565	COG1256	bacterial-type flagellum assembly
FIU96_RS10565	COG4786	Flagellar basal body rod
FIU96_RS10575	COG1706	bacterial-type flagellum-dependent cell motility
FIU96_RS10580	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FIU96_RS10585	COG4786	Flagellar basal body rod
FIU96_RS10590	COG4787	bacterial-type flagellum-dependent cell motility
FIU96_RS10595	COG1749	Flagellar hook protein flgE
FIU96_RS10600	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FIU96_RS10605	COG1558	bacterial-type flagellum-dependent cell motility
FIU96_RS10610	COG1815	bacterial-type flagellum-dependent cell motility
FIU96_RS10625	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FIU96_RS10625	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FIU96_RS10630	COG0842	Transport permease protein
FIU96_RS10635	COG1131	(ABC) transporter
FIU96_RS10645	COG3437	response regulator, receiver
FIU96_RS10660	COG1840	ABC-type Fe3 transport system, periplasmic component
FIU96_RS10665	COG1178	ABC-type Fe3 transport system permease component
FIU96_RS10670	COG1022	Amp-dependent synthetase and ligase
FIU96_RS10680	COG4120	Belongs to the binding-protein-dependent transport system permease family
FIU96_RS10685	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FIU96_RS10725	COG1942	4-Oxalocrotonate Tautomerase
FIU96_RS10735	COG3039	Transposase
FIU96_RS10745	COG1215	transferase activity, transferring glycosyl groups
FIU96_RS10765	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FIU96_RS10780	COG0123	including yeast histone deacetylase and acetoin utilization protein
FIU96_RS10800	COG0454	-acetyltransferase
FIU96_RS10815	COG3588	fructose-bisphosphate aldolase
FIU96_RS10820	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FIU96_RS10825	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FIU96_RS10830	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FIU96_RS10840	COG0326	Molecular chaperone. Has ATPase activity
FIU96_RS10880	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FIU96_RS10885	COG4181	ATPase activity
FIU96_RS10905	COG1362	aminopeptidase activity
FIU96_RS10920	COG0116	Belongs to the methyltransferase superfamily
FIU96_RS10920	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FIU96_RS10925	COG3130	regulation of translation
FIU96_RS10930	COG0167	dihydroorotate dehydrogenase activity
FIU96_RS10935	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FIU96_RS10955	COG0436	Aminotransferase
FIU96_RS10965	COG0284	orotidine-5'-phosphate decarboxylase activity
FIU96_RS10970	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FIU96_RS10980	COG0776	regulation of translation
FIU96_RS10990	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FIU96_RS10995	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FIU96_RS11000	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FIU96_RS11005	COG1605	Chorismate mutase
FIU96_RS11005	COG0077	Prephenate dehydratase
FIU96_RS11020	COG0788	formyltetrahydrofolate deformylase activity
FIU96_RS11025	COG0405	Gamma-glutamyltransferase
FIU96_RS11035	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FIU96_RS11045	COG1067	ATP-dependent peptidase activity
FIU96_RS11050	COG0625	glutathione transferase activity
FIU96_RS11055	COG0577	efflux transmembrane transporter activity
FIU96_RS11055	COG1136	(ABC) transporter
FIU96_RS11090	COG0494	nUDIX hydrolase
FIU96_RS11120	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
FIU96_RS11125	COG3344	reverse transcriptase
FIU96_RS11275	COG2154	pterin-4-alpha-carbinolamine dehydratase
FIU96_RS11280	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FIU96_RS11290	COG0587	DNA-directed DNA polymerase activity
FIU96_RS11295	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
FIU96_RS11305	COG3630	sodium ion export across plasma membrane
FIU96_RS11310	COG0513	Belongs to the DEAD box helicase family
FIU96_RS11315	COG3122	Protein conserved in bacteria
FIU96_RS11335	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FIU96_RS11340	COG0527	aspartate kinase activity
FIU96_RS11345	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FIU96_RS11355	COG0795	lipopolysaccharide-transporting ATPase activity
FIU96_RS11360	COG0795	lipopolysaccharide-transporting ATPase activity
FIU96_RS11365	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FIU96_RS11370	COG2927	DNA polymerase III (CHI subunit)
FIU96_RS11375	COG0525	valine-tRNA ligase activity
FIU96_RS11385	COG2096	Adenosyltransferase
FIU96_RS11390	COG0840	transmembrane signaling receptor activity
FIU96_RS11400	COG3023	N-Acetylmuramoyl-L-alanine amidase
FIU96_RS11415	COG3098	single-species biofilm formation
FIU96_RS11420	COG1192	Involved in chromosome partitioning
FIU96_RS11425	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FIU96_RS11440	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FIU96_RS11445	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FIU96_RS11455	COG3977	Valine--pyruvate aminotransferase
FIU96_RS11460	COG3068	Protein conserved in bacteria
FIU96_RS11465	COG0717	Belongs to the dCTP deaminase family
FIU96_RS11470	COG0489	protein tyrosine kinase activity
FIU96_RS11475	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FIU96_RS11475	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FIU96_RS11480	COG4657	Part of a membrane complex involved in electron transport
FIU96_RS11485	COG2878	Part of a membrane complex involved in electron transport
FIU96_RS11490	COG4656	Part of a membrane complex involved in electron transport
FIU96_RS11495	COG4658	electron transport chain
FIU96_RS11505	COG4660	Part of a membrane complex involved in electron transport
FIU96_RS11510	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FIU96_RS11535	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FIU96_RS11540	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FIU96_RS11545	COG0585	pseudouridine synthase activity
FIU96_RS11550	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FIU96_RS11555	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FIU96_RS11560	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FIU96_RS11565	COG0148	phosphopyruvate hydratase activity
FIU96_RS11570	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FIU96_RS11575	COG0504	CTP synthase activity
FIU96_RS11580	COG0037	tRNA processing
FIU96_RS11585	COG0825	malonyl-CoA metabolic process
FIU96_RS11595	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FIU96_RS11600	COG1393	Belongs to the ArsC family
FIU96_RS11615	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FIU96_RS11625	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
FIU96_RS11630	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
FIU96_RS11635	COG0235	Class ii aldolase
FIU96_RS11655	COG2840	Smr protein MutS2
FIU96_RS11660	COG0517	IMP dehydrogenase activity
FIU96_RS11665	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FIU96_RS11675	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FIU96_RS11685	COG0784	Response regulator, receiver
FIU96_RS11685	COG2205	protein histidine kinase activity
FIU96_RS11695	COG2205	protein histidine kinase activity
FIU96_RS11735	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FIU96_RS11750	COG0494	nUDIX hydrolase
FIU96_RS11760	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FIU96_RS11760	COG3323	Protein of unknown function (DUF1653)
FIU96_RS11765	COG0047	phosphoribosylformylglycinamidine synthase activity
FIU96_RS11765	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FIU96_RS11770	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FIU96_RS11775	COG2137	regulation of response to DNA damage stimulus
FIU96_RS11790	COG0183	Belongs to the thiolase family
FIU96_RS11795	COG1250	3-hydroxyacyl-CoA dehydrogenase
FIU96_RS11795	COG1024	Enoyl-CoA hydratase
FIU96_RS11810	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
FIU96_RS11815	COG0402	S-adenosylhomocysteine deaminase activity
FIU96_RS11820	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FIU96_RS11825	COG0546	phosphoglycolate phosphatase activity
FIU96_RS11830	COG1028	Short-chain dehydrogenase reductase Sdr
FIU96_RS11840	COG3022	response to hydroperoxide
FIU96_RS11850	COG2974	May be involved in recombination
FIU96_RS11855	COG0045	succinate-CoA ligase (ADP-forming) activity
FIU96_RS11855	COG1042	CoA-binding domain protein
FIU96_RS11855	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FIU96_RS11860	COG0123	including yeast histone deacetylase and acetoin utilization protein
FIU96_RS11870	COG0418	dihydroorotase activity
FIU96_RS11875	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FIU96_RS11880	COG4221	oxidoreductase activity
FIU96_RS11890	COG1025	Belongs to the peptidase M16 family
FIU96_RS11900	COG1215	transferase activity, transferring glycosyl groups
FIU96_RS12120	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
FIU96_RS12205	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FIU96_RS12210	COG0840	transmembrane signaling receptor activity
FIU96_RS12220	COG0009	L-threonylcarbamoyladenylate synthase
FIU96_RS12225	COG0271	Belongs to the BolA IbaG family
FIU96_RS12230	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FIU96_RS12245	COG5002	protein histidine kinase activity
FIU96_RS12260	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FIU96_RS12265	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FIU96_RS12270	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FIU96_RS12275	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FIU96_RS12280	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FIU96_RS12300	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FIU96_RS12310	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FIU96_RS12315	COG0233	cytoplasmic translational termination
FIU96_RS12320	COG0528	UMP kinase activity
FIU96_RS12325	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FIU96_RS12330	COG0052	Belongs to the universal ribosomal protein uS2 family
FIU96_RS12340	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FIU96_RS12345	COG0436	Aminotransferase
FIU96_RS12350	COG1393	Belongs to the ArsC family
FIU96_RS12355	COG2171	N-acyltransferase activity
FIU96_RS12360	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FIU96_RS12365	COG2900	Belongs to the SlyX family
FIU96_RS12390	COG0346	lactoylglutathione lyase activity
FIU96_RS12460	COG0366	Alpha amylase catalytic
FIU96_RS12465	COG1215	transferase activity, transferring glycosyl groups
FIU96_RS12475	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FIU96_RS12485	COG1666	GTP binding
FIU96_RS12490	COG0745	RESPONSE REGULATOR receiver
FIU96_RS12500	COG0137	argininosuccinate synthase activity
FIU96_RS12515	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FIU96_RS12565	COG3012	SEC-C Motif Domain Protein
FIU96_RS12585	COG2925	Exonuclease
FIU96_RS12590	COG3328	transposase activity
FIU96_RS12610	COG2201	protein-glutamate methylesterase activity
FIU96_RS12615	COG3706	GGDEF domain
FIU96_RS12645	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FIU96_RS12650	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FIU96_RS12670	COG0166	Belongs to the GPI family
FIU96_RS12680	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FIU96_RS12715	COG2244	polysaccharide biosynthetic process
FIU96_RS12725	COG3335	DDE superfamily endonuclease
FIU96_RS12730	COG2030	dehydratase
FIU96_RS12735	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FIU96_RS12750	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FIU96_RS12870	COG4964	Belongs to the GSP D family
FIU96_RS12910	COG0840	transmembrane signaling receptor activity
FIU96_RS12940	COG2203	Gaf domain
FIU96_RS12940	COG3706	GGDEF domain
FIU96_RS12940	COG4251	negative regulation of phosphorylation
FIU96_RS12940	COG5001	Diguanylate cyclase
FIU96_RS12960	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FIU96_RS12965	COG2863	cytochrome
FIU96_RS12970	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FIU96_RS12975	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
FIU96_RS12980	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FIU96_RS12995	COG3123	guanosine phosphorylase activity
FIU96_RS13025	COG0367	asparagine synthase
FIU96_RS13040	COG0463	Glycosyl transferase, family 2
FIU96_RS13065	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FIU96_RS13070	COG0237	dephospho-CoA kinase activity
FIU96_RS13080	COG1720	tRNA m6t6A37 methyltransferase activity
FIU96_RS13085	COG2205	protein histidine kinase activity
FIU96_RS13085	COG0784	Response regulator, receiver
FIU96_RS13085	COG5002	protein histidine kinase activity
FIU96_RS13090	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FIU96_RS13110	COG0204	Acyl-transferase
FIU96_RS13115	COG2197	response regulator
FIU96_RS13130	COG0183	Belongs to the thiolase family
FIU96_RS13135	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FIU96_RS13150	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FIU96_RS13155	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FIU96_RS13160	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FIU96_RS13165	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FIU96_RS13170	COG5007	Belongs to the BolA IbaG family
FIU96_RS13185	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FIU96_RS13190	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FIU96_RS13195	COG1127	ABC transporter
FIU96_RS13205	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FIU96_RS13220	COG1137	ATPase activity
FIU96_RS13240	COG1660	Displays ATPase and GTPase activities
FIU96_RS13245	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FIU96_RS13250	COG2239	Acts as a magnesium transporter
FIU96_RS13255	COG3028	Belongs to the UPF0307 family
FIU96_RS13260	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FIU96_RS13275	COG0424	maF-like protein
FIU96_RS13280	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FIU96_RS13285	COG1792	Involved in formation and maintenance of cell shape
FIU96_RS13290	COG1077	Cell shape determining protein MreB Mrl
FIU96_RS13295	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FIU96_RS13300	COG0154	amidase activity
FIU96_RS13305	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FIU96_RS13310	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FIU96_RS13320	COG0175	sulfate reduction
FIU96_RS13335	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FIU96_RS13340	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FIU96_RS13345	COG1702	phosphate starvation-inducible protein PhoH
FIU96_RS13350	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FIU96_RS13355	COG4535	Mg2 and Co2 transporter CorC
FIU96_RS13360	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FIU96_RS13370	COG0495	leucyl-tRNA aminoacylation
FIU96_RS13375	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
FIU96_RS13380	COG1466	dna polymerase III delta subunit
FIU96_RS13395	COG1960	acyl-CoA dehydrogenase activity
FIU96_RS13400	COG1960	acyl-CoA dehydrogenase activity
FIU96_RS13415	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FIU96_RS13425	COG0156	8-amino-7-oxononanoate synthase activity
FIU96_RS13430	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FIU96_RS13435	COG1040	competence protein
FIU96_RS13440	COG0579	oxidoreductase
FIU96_RS13450	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FIU96_RS13460	COG4106	trans-aconitate 2-methyltransferase activity
FIU96_RS13465	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FIU96_RS13470	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FIU96_RS13475	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FIU96_RS13480	COG0330	HflC and HflK could
FIU96_RS13485	COG0330	HflC and HflK could
FIU96_RS13490	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FIU96_RS13495	COG1923	regulation of RNA biosynthetic process
FIU96_RS13500	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FIU96_RS13510	COG0860	N-Acetylmuramoyl-L-alanine amidase
FIU96_RS13515	COG0802	atpase or kinase
FIU96_RS13520	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FIU96_RS13520	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FIU96_RS13530	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FIU96_RS13535	COG1162	GTPase activity
FIU96_RS13550	COG0688	phosphatidylethanolamine metabolic process
FIU96_RS13555	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FIU96_RS13560	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FIU96_RS13565	COG1509	lysine 2,3-aminomutase activity
FIU96_RS13575	COG2200	EAL domain
FIU96_RS13580	COG0560	Phosphoserine phosphatase
FIU96_RS13580	COG3830	Belongs to the UPF0237 family
FIU96_RS13595	COG0840	transmembrane signaling receptor activity
FIU96_RS13600	COG2353	YceI-like domain
FIU96_RS13605	COG3038	cytochrome b561
FIU96_RS13610	COG2200	EAL domain
FIU96_RS13610	COG2199	diguanylate cyclase activity
FIU96_RS13615	COG3273	potassium ion transport
FIU96_RS13615	COG0471	metal ion transport
FIU96_RS13630	COG1404	Belongs to the peptidase S8 family
FIU96_RS13650	COG1309	transcriptional regulator
FIU96_RS13660	COG1028	Short-chain dehydrogenase reductase Sdr
FIU96_RS13665	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FIU96_RS13670	COG1960	acyl-CoA dehydrogenase activity
FIU96_RS13675	COG1024	Enoyl-CoA hydratase
FIU96_RS13685	COG0300	oxidoreductase activity
FIU96_RS13690	COG0318	PFAM AMP-dependent synthetase and ligase
FIU96_RS13705	COG2860	membrane
FIU96_RS13710	COG2252	PERMEase
FIU96_RS13715	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FIU96_RS13720	COG0179	Fumarylacetoacetate (FAA) hydrolase
FIU96_RS13725	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FIU96_RS13735	COG0277	FAD linked oxidase domain protein
FIU96_RS13740	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FIU96_RS13750	COG2885	chlorophyll binding
FIU96_RS13790	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FIU96_RS13805	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FIU96_RS13840	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FIU96_RS13845	COG1024	Enoyl-CoA hydratase
FIU96_RS13850	COG1960	acyl-CoA dehydrogenase activity
FIU96_RS13855	COG4977	sequence-specific DNA binding
FIU96_RS13860	COG1902	pentaerythritol trinitrate reductase activity
FIU96_RS13860	COG0446	pyridine nucleotide-disulphide oxidoreductase
FIU96_RS13865	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FIU96_RS13865	COG2111	Na H antiporter
FIU96_RS13870	COG2111	Na H antiporter
FIU96_RS13875	COG1006	Multisubunit Na H antiporter MnhC subunit
FIU96_RS13880	COG0651	ATP synthesis coupled electron transport
FIU96_RS13885	COG1863	multisubunit Na H antiporter MnhE subunit
FIU96_RS13890	COG2212	antiporter activity
FIU96_RS13895	COG1320	monovalent cation:proton antiporter activity
FIU96_RS13900	COG0318	PFAM AMP-dependent synthetase and ligase
FIU96_RS13905	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FIU96_RS13910	COG0023	Translation Initiation Factor
FIU96_RS13920	COG1739	Uncharacterized protein family UPF0029
FIU96_RS13935	COG0745	RESPONSE REGULATOR receiver
FIU96_RS13985	COG0733	neurotransmitter:sodium symporter activity
FIU96_RS14005	COG0488	(ABC) transporter
FIU96_RS14010	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FIU96_RS14025	COG0583	DNA-binding transcription factor activity
FIU96_RS14055	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FIU96_RS14095	COG1301	dicarboxylic acid transport
FIU96_RS14100	COG0741	lytic transglycosylase activity
FIU96_RS14115	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FIU96_RS14120	COG1607	acyl-coa hydrolase
FIU96_RS14155	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FIU96_RS14180	COG0702	epimerase
FIU96_RS14190	COG1801	Protein of unknown function DUF72
FIU96_RS14200	COG1028	Short-chain dehydrogenase reductase Sdr
FIU96_RS14210	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FIU96_RS14250	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FIU96_RS14255	COG0523	cobalamin synthesis protein
FIU96_RS14260	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FIU96_RS14290	COG0653	protein targeting
FIU96_RS14315	COG0702	epimerase
FIU96_RS14320	COG0625	glutathione transferase activity
FIU96_RS14330	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FIU96_RS14360	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FIU96_RS14360	COG2169	Transcriptional regulator
FIU96_RS14380	COG1061	Type III restriction enzyme res subunit
FIU96_RS14395	COG2132	Multicopper oxidase
FIU96_RS14420	COG0693	protein deglycase activity
FIU96_RS14465	COG3577	Aspartyl protease
FIU96_RS14485	COG3039	Transposase
FIU96_RS14495	COG1917	Cupin 2, conserved barrel domain protein
FIU96_RS14495	COG2207	Transcriptional regulator
FIU96_RS14585	COG0411	ABC transporter
FIU96_RS14615	COG1802	Transcriptional regulator
FIU96_RS14620	COG1555	photosystem II stabilization
FIU96_RS14620	COG1596	polysaccharide export
FIU96_RS14660	COG1054	Belongs to the UPF0176 family
FIU96_RS14665	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FIU96_RS14670	COG2070	2-Nitropropane dioxygenase
FIU96_RS14675	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
FIU96_RS14705	COG0789	Transcriptional regulator
FIU96_RS14710	COG0484	heat shock protein binding
FIU96_RS14750	COG2307	Protein conserved in bacteria
FIU96_RS14750	COG2308	Evidence 4 Homologs of previously reported genes of
FIU96_RS14765	COG2308	Evidence 4 Homologs of previously reported genes of
FIU96_RS14775	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FIU96_RS14780	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FIU96_RS14790	COG0126	phosphoglycerate kinase activity
FIU96_RS14795	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FIU96_RS14800	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FIU96_RS14805	COG0640	Transcriptional regulator
FIU96_RS14810	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FIU96_RS14815	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FIU96_RS14820	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FIU96_RS14825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FIU96_RS14830	COG0765	amino acid transport
FIU96_RS14840	COG0300	oxidoreductase activity
FIU96_RS14855	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FIU96_RS14860	COG4399	Belongs to the UPF0754 family
FIU96_RS14870	COG1295	ribonuclease BN
FIU96_RS14870	COG1959	2 iron, 2 sulfur cluster binding
FIU96_RS14875	COG2182	Extracellular solute-binding protein
FIU96_RS14880	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FIU96_RS14885	COG0500	methyltransferase
FIU96_RS14890	COG2766	serine protein kinase
FIU96_RS14895	COG2718	Belongs to the UPF0229 family
FIU96_RS14900	COG2719	SpoVR family
FIU96_RS14905	COG4772	TonB-dependent receptor
FIU96_RS14920	COG0385	Bile acid
FIU96_RS14930	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FIU96_RS14940	COG2610	gluconate transmembrane transporter activity
FIU96_RS14950	COG1017	nitric oxide dioxygenase activity
FIU96_RS14950	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FIU96_RS14960	COG1959	2 iron, 2 sulfur cluster binding
FIU96_RS14965	COG2832	Protein of unknown function (DUF454)
FIU96_RS14985	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FIU96_RS14995	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FIU96_RS15015	COG0348	domain, Protein
FIU96_RS15015	COG3901	Regulator of nitric oxide reductase transcription
FIU96_RS15035	COG2181	nitrate reductase activity
FIU96_RS15040	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
FIU96_RS15050	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FIU96_RS15060	COG3850	Histidine kinase
FIU96_RS15065	COG2197	response regulator
FIU96_RS15070	COG3154	lipid carrier protein
FIU96_RS15085	COG0826	peptidase U32
FIU96_RS15090	COG0826	peptidase U32
FIU96_RS15105	COG3046	protein related to deoxyribodipyrimidine photolyase
FIU96_RS15115	COG0546	phosphoglycolate phosphatase activity
FIU96_RS15125	COG0415	Belongs to the DNA photolyase family
FIU96_RS15130	COG0651	ATP synthesis coupled electron transport
FIU96_RS15135	COG0651	ATP synthesis coupled electron transport
FIU96_RS15140	COG0651	ATP synthesis coupled electron transport
FIU96_RS15180	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FIU96_RS15190	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FIU96_RS15255	COG1136	(ABC) transporter
FIU96_RS15255	COG0577	efflux transmembrane transporter activity
FIU96_RS15325	COG2217	Heavy metal translocating P-type atpase
FIU96_RS15350	COG2132	Multicopper oxidase
FIU96_RS15400	COG2010	Cytochrome c
FIU96_RS15405	COG3256	nitric oxide reductase
FIU96_RS15435	COG0714	Associated with various cellular activities
FIU96_RS15450	COG2010	Cytochrome c
FIU96_RS15480	COG0535	radical SAM domain protein
FIU96_RS15485	COG1648	precorrin-2 dehydrogenase activity
FIU96_RS15485	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FIU96_RS15505	COG2067	long-chain fatty acid transport protein
FIU96_RS15510	COG0655	NAD(P)H dehydrogenase (quinone) activity
FIU96_RS15515	COG1272	protein, Hemolysin III
FIU96_RS15525	COG2223	nitrite transmembrane transporter activity
FIU96_RS15530	COG2223	nitrite transmembrane transporter activity
FIU96_RS15550	COG0659	secondary active sulfate transmembrane transporter activity
FIU96_RS15575	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FIU96_RS15590	COG0826	peptidase U32
FIU96_RS15595	COG0719	Fe-S assembly protein
FIU96_RS15600	COG0396	ATPase activity
FIU96_RS15605	COG0719	Fe-S assembly protein
FIU96_RS15610	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FIU96_RS15615	COG0316	Belongs to the HesB IscA family
FIU96_RS15620	COG2151	metal-sulfur cluster biosynthetic enzyme
FIU96_RS15625	COG2166	iron-sulfur cluster assembly
FIU96_RS15645	COG0617	tRNA 3'-terminal CCA addition
FIU96_RS15650	COG0300	oxidoreductase activity
FIU96_RS15655	COG0183	Belongs to the thiolase family
FIU96_RS15660	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FIU96_RS15670	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FIU96_RS15675	COG4558	Periplasmic binding protein
FIU96_RS15695	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FIU96_RS15700	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FIU96_RS15705	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FIU96_RS15710	COG4942	peptidase
FIU96_RS15715	COG0793	Belongs to the peptidase S41A family
FIU96_RS15725	COG0107	imidazoleglycerol-phosphate synthase activity
FIU96_RS15730	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FIU96_RS15735	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FIU96_RS15740	COG0131	Imidazoleglycerol-phosphate dehydratase
FIU96_RS15755	COG1194	a g-specific adenine glycosylase
FIU96_RS15760	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
FIU96_RS15785	COG2072	flavoprotein involved in K transport
FIU96_RS15795	COG0814	amino acid
FIU96_RS15805	COG2351	hydroxyisourate hydrolase activity
FIU96_RS15830	COG0596	Alpha beta hydrolase
FIU96_RS15855	COG0583	DNA-binding transcription factor activity
FIU96_RS15860	COG2814	Major facilitator Superfamily
FIU96_RS15870	COG0247	lactate metabolic process
FIU96_RS15875	COG0277	FAD linked oxidase domain protein
FIU96_RS15880	COG0277	FAD linked oxidase domain protein
FIU96_RS15890	COG2186	Transcriptional regulator
FIU96_RS15900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FIU96_RS15915	COG2988	succinylglutamate desuccinylase activity
FIU96_RS15920	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FIU96_RS15935	COG3724	N-succinylarginine dihydrolase activity
FIU96_RS15940	COG1012	belongs to the aldehyde dehydrogenase family
FIU96_RS15955	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FIU96_RS15960	COG2176	DNA-directed DNA polymerase activity
FIU96_RS15970	COG1960	acyl-CoA dehydrogenase activity
FIU96_RS15985	COG1509	lysine 2,3-aminomutase activity
FIU96_RS16010	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FIU96_RS16020	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FIU96_RS16075	COG1185	polyribonucleotide nucleotidyltransferase activity
FIU96_RS16080	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FIU96_RS16085	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FIU96_RS16090	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FIU96_RS16095	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FIU96_RS16100	COG0195	Participates in both transcription termination and antitermination
FIU96_RS16105	COG0779	Required for maturation of 30S ribosomal subunits
FIU96_RS16120	COG0149	triose-phosphate isomerase activity
FIU96_RS16125	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FIU96_RS16130	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FIU96_RS16135	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FIU96_RS16145	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FIU96_RS16150	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FIU96_RS16160	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FIU96_RS16165	COG0484	heat shock protein binding
FIU96_RS16170	COG0443	Heat shock 70 kDa protein
FIU96_RS16175	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FIU96_RS16180	COG0497	DNA recombination
FIU96_RS16190	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FIU96_RS16195	COG2914	Belongs to the UPF0125 (RnfH) family
FIU96_RS16200	COG2867	negative regulation of translational initiation
FIU96_RS16205	COG0733	neurotransmitter:sodium symporter activity
FIU96_RS16210	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FIU96_RS16250	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FIU96_RS16270	COG0835	chemotaxis
FIU96_RS16270	COG0784	Response regulator, receiver
FIU96_RS16295	COG0579	oxidoreductase
FIU96_RS16315	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FIU96_RS16360	COG0535	radical SAM domain protein
FIU96_RS16375	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FIU96_RS16385	COG3901	Regulator of nitric oxide reductase transcription
FIU96_RS16385	COG0348	domain, Protein
FIU96_RS16390	COG0604	alcohol dehydrogenase
FIU96_RS16395	COG1309	transcriptional regulator
FIU96_RS16425	COG1309	transcriptional regulator
FIU96_RS16435	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FIU96_RS16440	COG1174	glycine betaine transport
FIU96_RS16445	COG1116	anion transmembrane transporter activity
FIU96_RS16480	COG4585	Histidine kinase
FIU96_RS16495	COG1131	(ABC) transporter
FIU96_RS16510	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FIU96_RS16525	COG2205	protein histidine kinase activity
FIU96_RS16525	COG0784	Response regulator, receiver
FIU96_RS16560	COG2226	methyltransferase
FIU96_RS16570	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FIU96_RS16575	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FIU96_RS16580	COG0140	phosphoribosyl-ATP diphosphatase activity
FIU96_RS16585	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FIU96_RS16590	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FIU96_RS16605	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FIU96_RS16610	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FIU96_RS16615	COG0006	proline dipeptidase activity
FIU96_RS16620	COG3079	Belongs to the UPF0149 family
FIU96_RS16635	COG4181	ATPase activity
FIU96_RS16660	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FIU96_RS16665	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FIU96_RS16670	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FIU96_RS16675	COG1960	acyl-CoA dehydrogenase activity
FIU96_RS16710	COG3501	Rhs element vgr protein
FIU96_RS16725	COG5001	Diguanylate cyclase
FIU96_RS16725	COG3300	MHYT domain
FIU96_RS16745	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FIU96_RS16750	COG0511	ligase activity, forming carbon-carbon bonds
FIU96_RS16760	COG2264	protein methyltransferase activity
FIU96_RS16785	COG0151	Belongs to the GarS family
FIU96_RS16800	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FIU96_RS16800	COG4651	solute:proton antiporter activity
FIU96_RS16805	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FIU96_RS16820	COG1309	transcriptional regulator
FIU96_RS16825	COG0471	metal ion transport
FIU96_RS16825	COG0490	domain, Protein
FIU96_RS16875	COG0517	IMP dehydrogenase activity
FIU96_RS16900	COG0659	secondary active sulfate transmembrane transporter activity
FIU96_RS16925	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FIU96_RS16935	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FIU96_RS16950	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FIU96_RS16970	COG0783	Belongs to the Dps family
FIU96_RS16985	COG1280	lysine exporter protein (LysE YggA)
FIU96_RS16990	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FIU96_RS17010	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FIU96_RS17025	COG0840	transmembrane signaling receptor activity
FIU96_RS17035	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FIU96_RS17050	COG2197	response regulator
FIU96_RS17065	COG0483	inositol monophosphate 1-phosphatase activity
FIU96_RS17070	COG1309	transcriptional regulator
FIU96_RS17075	COG2022	thiamine diphosphate biosynthetic process
FIU96_RS17085	COG2363	Small membrane protein
FIU96_RS17090	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FIU96_RS17095	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FIU96_RS17100	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FIU96_RS17105	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FIU96_RS17110	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FIU96_RS17115	COG3178	'Phosphotransferase
FIU96_RS17125	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FIU96_RS17135	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FIU96_RS17140	COG0546	phosphoglycolate phosphatase activity
FIU96_RS17150	COG0512	Glutamine amidotransferase of anthranilate synthase
FIU96_RS17155	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FIU96_RS17160	COG0134	indole-3-glycerol-phosphate synthase activity
FIU96_RS17185	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FIU96_RS17195	COG1082	Xylose isomerase domain protein TIM barrel
FIU96_RS17205	COG1120	ATPase activity
FIU96_RS17210	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FIU96_RS17220	COG4771	TonB-dependent receptor
FIU96_RS17230	COG0745	RESPONSE REGULATOR receiver
FIU96_RS17240	COG0446	pyridine nucleotide-disulphide oxidoreductase
FIU96_RS17315	COG1765	OsmC-like protein
FIU96_RS17320	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FIU96_RS17330	COG3954	Phosphoribulokinase
FIU96_RS17345	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FIU96_RS17345	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FIU96_RS17350	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FIU96_RS17360	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FIU96_RS17370	COG0756	dUTP diphosphatase activity
FIU96_RS17375	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FIU96_RS17380	COG2003	Belongs to the UPF0758 family
FIU96_RS17385	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FIU96_RS17390	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FIU96_RS17410	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FIU96_RS17435	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FIU96_RS17445	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FIU96_RS17460	COG1309	transcriptional regulator
FIU96_RS17465	COG1960	acyl-CoA dehydrogenase activity
FIU96_RS17475	COG0076	glutamate decarboxylase activity
FIU96_RS17485	COG0306	phosphate transporter
FIU96_RS17505	COG1946	Acyl-CoA thioesterase
FIU96_RS17520	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
FIU96_RS17525	COG3161	chorismate lyase activity
FIU96_RS17530	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FIU96_RS17545	COG0745	RESPONSE REGULATOR receiver
FIU96_RS17550	COG2951	lytic endotransglycosylase activity
FIU96_RS17565	COG1187	pseudouridine synthase activity
FIU96_RS17570	COG0252	asparaginase activity
FIU96_RS17575	COG1686	Belongs to the peptidase S11 family
FIU96_RS17580	COG2203	Gaf domain
FIU96_RS17580	COG3706	GGDEF domain
FIU96_RS17580	COG5001	Diguanylate cyclase
FIU96_RS17580	COG4251	negative regulation of phosphorylation
FIU96_RS17590	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
FIU96_RS17615	COG1278	Cold shock
FIU96_RS17620	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FIU96_RS17625	COG1960	acyl-CoA dehydrogenase activity
FIU96_RS17630	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FIU96_RS17650	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
FIU96_RS17655	COG0668	transmembrane transport
FIU96_RS17660	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FIU96_RS17665	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FIU96_RS17670	COG0537	adenosine 5'-monophosphoramidase activity
FIU96_RS17675	COG0704	Plays a role in the regulation of phosphate uptake
FIU96_RS17680	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FIU96_RS17685	COG0581	inorganic phosphate transmembrane transporter activity
FIU96_RS17690	COG0573	inorganic phosphate transmembrane transporter activity
FIU96_RS17700	COG1607	acyl-coa hydrolase
FIU96_RS17705	COG0167	dihydroorotate dehydrogenase activity
FIU96_RS17710	COG0674	pyruvate-flavodoxin oxidoreductase activity
FIU96_RS17710	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FIU96_RS17710	COG1013	pyruvate-flavodoxin oxidoreductase activity
FIU96_RS17725	COG0390	transport system, permease component
FIU96_RS17730	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FIU96_RS17750	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FIU96_RS17755	COG0640	Transcriptional regulator
FIU96_RS17760	COG0431	NADPH-dependent FMN reductase
FIU96_RS17765	COG0798	PFAM Bile acid sodium symporter
FIU96_RS17770	COG1968	undecaprenyl-diphosphatase activity
FIU96_RS17775	COG0210	DNA helicase
FIU96_RS17780	COG0840	transmembrane signaling receptor activity
FIU96_RS17795	COG1012	belongs to the aldehyde dehydrogenase family
FIU96_RS17805	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FIU96_RS17805	COG0301	tRNA thio-modification
FIU96_RS17810	COG1611	Belongs to the LOG family
FIU96_RS17820	COG1024	Enoyl-CoA hydratase
FIU96_RS17830	COG1444	tRNA N-acetyltransferase activity
FIU96_RS17840	COG0210	DNA helicase
FIU96_RS17855	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FIU96_RS17870	COG0084	hydrolase, TatD family'
FIU96_RS17895	COG2431	L-lysine efflux transmembrane transporter activity
FIU96_RS17910	COG4565	transcriptional regulatory protein
FIU96_RS17920	COG5002	protein histidine kinase activity
FIU96_RS17925	COG5002	protein histidine kinase activity
FIU96_RS17935	COG5002	protein histidine kinase activity
FIU96_RS17935	COG2198	Histidine kinase
FIU96_RS17935	COG0784	Response regulator, receiver
FIU96_RS17940	COG3437	response regulator, receiver
FIU96_RS17945	COG0840	transmembrane signaling receptor activity
FIU96_RS17975	COG0204	Acyl-transferase
FIU96_RS17990	COG0745	RESPONSE REGULATOR receiver
FIU96_RS17995	COG2205	protein histidine kinase activity
FIU96_RS18010	COG3706	GGDEF domain
FIU96_RS18030	COG4067	protein conserved in archaea
FIU96_RS18030	COG0189	ligase activity
FIU96_RS18035	COG1793	dna ligase
FIU96_RS18050	COG0443	Heat shock 70 kDa protein
FIU96_RS18055	COG2214	Heat shock protein DnaJ domain protein
FIU96_RS18080	COG3789	protein conserved in bacteria
FIU96_RS18095	COG0754	glutathionylspermidine amidase activity
FIU96_RS18155	COG3501	Rhs element vgr protein
FIU96_RS18175	COG3829	transcription factor binding
FIU96_RS18245	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FIU96_RS18265	COG3622	Belongs to the hyi family
FIU96_RS18270	COG2084	Dehydrogenase
FIU96_RS18280	COG2177	Part of the ABC transporter FtsEX involved in
FIU96_RS18285	COG2884	Cell division ATP-binding protein ftsE
FIU96_RS18290	COG0552	protein localization to endoplasmic reticulum
FIU96_RS18295	COG0742	ribosomal rna small subunit methyltransferase
FIU96_RS18305	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FIU96_RS18315	COG1011	Hydrolase
FIU96_RS18320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FIU96_RS18325	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FIU96_RS18330	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FIU96_RS18360	COG0540	Belongs to the ATCase OTCase family
FIU96_RS18365	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FIU96_RS18370	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FIU96_RS18375	COG1678	Uncharacterized ACR, COG1678
FIU96_RS18385	COG0189	ligase activity
FIU96_RS18405	COG0840	transmembrane signaling receptor activity
FIU96_RS18415	COG2198	Histidine kinase
FIU96_RS18415	COG0784	Response regulator, receiver
FIU96_RS18415	COG0643	Histidine kinase
FIU96_RS18420	COG2201	protein-glutamate methylesterase activity
FIU96_RS18430	COG0735	belongs to the Fur family
FIU96_RS18435	COG1121	(ABC) transporter
FIU96_RS18440	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FIU96_RS18465	COG0302	gtp cyclohydrolase
FIU96_RS18470	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FIU96_RS18475	COG1832	CoA-binding protein
FIU96_RS18490	COG0789	Transcriptional regulator
FIU96_RS18495	COG2217	Heavy metal translocating P-type atpase
FIU96_RS18505	COG3706	GGDEF domain
FIU96_RS18550	COG0204	Acyl-transferase
FIU96_RS18565	COG0583	DNA-binding transcription factor activity
FIU96_RS18570	COG2814	Major facilitator Superfamily
FIU96_RS18575	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FIU96_RS18585	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FIU96_RS18585	COG2111	Na H antiporter
FIU96_RS18590	COG1006	Multisubunit Na H antiporter MnhC subunit
FIU96_RS18595	COG0651	ATP synthesis coupled electron transport
FIU96_RS18600	COG1863	multisubunit Na H antiporter MnhE subunit
FIU96_RS18605	COG2212	antiporter activity
FIU96_RS18610	COG1320	monovalent cation:proton antiporter activity
FIU96_RS18645	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FIU96_RS18665	COG1960	acyl-CoA dehydrogenase activity
FIU96_RS18675	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FIU96_RS18685	COG0583	DNA-binding transcription factor activity
FIU96_RS18705	COG2909	trisaccharide binding
FIU96_RS18710	COG3239	Fatty acid desaturase
FIU96_RS18715	COG1773	rubredoxin
FIU96_RS18740	COG3335	DDE superfamily endonuclease
FIU96_RS18760	COG0633	Ferredoxin
FIU96_RS18770	COG1309	transcriptional regulator
FIU96_RS18890	COG0697	spore germination
FIU96_RS18905	COG2095	MarC family integral membrane protein
FIU96_RS18910	COG1187	pseudouridine synthase activity
FIU96_RS18920	COG3328	transposase activity
FIU96_RS18960	COG3047	cAMP biosynthetic process
FIU96_RS18965	COG0513	Belongs to the DEAD box helicase family
FIU96_RS18990	COG2072	flavoprotein involved in K transport
FIU96_RS18995	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FIU96_RS19015	COG3634	alkyl hydroperoxide reductase activity
FIU96_RS19020	COG0450	alkyl hydroperoxide reductase
FIU96_RS19035	COG1012	belongs to the aldehyde dehydrogenase family
FIU96_RS19040	COG1309	transcriptional regulator
FIU96_RS19055	COG1595	DNA-templated transcription, initiation
FIU96_RS19060	COG1404	Belongs to the peptidase S8 family
FIU96_RS19075	COG0598	Magnesium transport protein CorA
FIU96_RS19110	COG2161	toxin-antitoxin pair type II binding
FIU96_RS19175	COG2161	toxin-antitoxin pair type II binding
FIU96_RS19325	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FIU96_RS19335	COG2207	Transcriptional regulator
FIU96_RS19335	COG1917	Cupin 2, conserved barrel domain protein
FIU96_RS19345	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FIU96_RS19345	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FIU96_RS19370	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FIU96_RS19400	COG2205	protein histidine kinase activity
FIU96_RS19400	COG2198	Histidine kinase
FIU96_RS19400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FIU96_RS19400	COG0784	Response regulator, receiver
FIU96_RS19415	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FIU96_RS19420	COG1116	anion transmembrane transporter activity
FIU96_RS19430	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FIU96_RS19460	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FIU96_RS19465	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FIU96_RS19470	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FIU96_RS19475	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FIU96_RS19480	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FIU96_RS19485	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FIU96_RS19490	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FIU96_RS19495	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FIU96_RS19505	COG0356	it plays a direct role in the translocation of protons across the membrane
FIU96_RS19510	COG3312	ion transport
FIU96_RS19515	COG1475	DNA binding
FIU96_RS19520	COG1192	Involved in chromosome partitioning
FIU96_RS19525	COG0357	Ribosomal RNA small subunit methyltransferase G
FIU96_RS19530	COG0445	tRNA wobble uridine modification
FIU96_RS19545	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FIU96_RS19560	COG1960	acyl-CoA dehydrogenase activity
FIU96_RS19570	COG4771	TonB-dependent receptor
FIU96_RS19575	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FIU96_RS19580	COG0706	membrane insertase activity
FIU96_RS19585	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FIU96_RS19590	COG0594	ribonuclease P activity
FIU96_RS19595	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FIU96_RS19690	COG0756	dUTP diphosphatase activity
FIU96_RS19735	COG0305	Participates in initiation and elongation during chromosome replication