locus-tag	class	description
IBG28_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IBG28_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IBG28_RS00020	COG0187	DNA topoisomerase II activity
IBG28_RS00025	COG0702	epimerase
IBG28_RS00030	COG1733	regulation of RNA biosynthetic process
IBG28_RS00045	COG3708	Transcriptional regulator
IBG28_RS00045	COG2207	Transcriptional regulator
IBG28_RS00055	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
IBG28_RS00060	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IBG28_RS00065	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IBG28_RS00070	COG0569	domain protein
IBG28_RS00080	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IBG28_RS00085	COG0242	peptide deformylase activity
IBG28_RS00090	COG0758	DNA mediated transformation
IBG28_RS00095	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
IBG28_RS00100	COG1218	3'(2'),5'-bisphosphate nucleotidase
IBG28_RS00105	COG0366	Alpha amylase catalytic
IBG28_RS00125	COG1653	transport
IBG28_RS00130	COG1609	Transcriptional regulator
IBG28_RS00140	COG0673	inositol 2-dehydrogenase activity
IBG28_RS00145	COG0673	inositol 2-dehydrogenase activity
IBG28_RS00155	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IBG28_RS00160	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IBG28_RS00170	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IBG28_RS00185	COG2186	Transcriptional regulator
IBG28_RS00190	COG4948	Mandelate Racemase Muconate Lactonizing
IBG28_RS00195	COG1063	alcohol dehydrogenase
IBG28_RS00200	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IBG28_RS00205	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
IBG28_RS00210	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IBG28_RS00215	COG0583	DNA-binding transcription factor activity
IBG28_RS00235	COG1012	belongs to the aldehyde dehydrogenase family
IBG28_RS00240	COG1802	Transcriptional regulator
IBG28_RS00255	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IBG28_RS00265	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IBG28_RS00270	COG3938	Belongs to the proline racemase family
IBG28_RS00275	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IBG28_RS00290	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IBG28_RS00295	COG1309	transcriptional regulator
IBG28_RS00300	COG1560	Kdo2-lipid A biosynthetic process
IBG28_RS00305	COG0408	coproporphyrinogen oxidase activity
IBG28_RS00310	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IBG28_RS00325	COG3485	protocatechuate 3,4-dioxygenase
IBG28_RS00330	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IBG28_RS00330	COG1017	nitric oxide dioxygenase activity
IBG28_RS00335	COG3604	Transcriptional regulator
IBG28_RS00350	COG0534	Mate efflux family protein
IBG28_RS00355	COG2186	Transcriptional regulator
IBG28_RS00360	COG0277	FAD linked oxidase domain protein
IBG28_RS00375	COG0583	DNA-binding transcription factor activity
IBG28_RS00385	COG1115	amino acid carrier protein
IBG28_RS00395	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IBG28_RS00405	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IBG28_RS00425	COG0109	protoheme IX farnesyltransferase activity
IBG28_RS00435	COG1028	Short-chain dehydrogenase reductase Sdr
IBG28_RS00460	COG2813	Specifically methylates the guanine in position
IBG28_RS00480	COG4774	siderophore transport
IBG28_RS00495	COG3251	PFAM MbtH domain protein
IBG28_RS00500	COG4615	Cyclic peptide transporter
IBG28_RS00505	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IBG28_RS00510	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IBG28_RS00515	COG1120	ATPase activity
IBG28_RS00525	COG4807	Protein conserved in bacteria
IBG28_RS00535	COG2207	Transcriptional regulator
IBG28_RS00545	COG4608	Belongs to the ABC transporter superfamily
IBG28_RS00550	COG0444	Belongs to the ABC transporter superfamily
IBG28_RS00555	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IBG28_RS00560	COG0601	transmembrane transport
IBG28_RS00565	COG0747	negative chemotaxis
IBG28_RS00570	COG2084	Dehydrogenase
IBG28_RS00600	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
IBG28_RS00615	COG0406	alpha-ribazole phosphatase activity
IBG28_RS00630	COG0534	Mate efflux family protein
IBG28_RS00645	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IBG28_RS00645	COG2169	Transcriptional regulator
IBG28_RS00650	COG0400	carboxylic ester hydrolase activity
IBG28_RS00680	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IBG28_RS00685	COG2818	Glycosylase
IBG28_RS00695	COG0583	DNA-binding transcription factor activity
IBG28_RS00700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IBG28_RS00705	COG4597	amino acid ABC transporter
IBG28_RS00710	COG0765	amino acid transport
IBG28_RS00715	COG1126	abc transporter atp-binding protein
IBG28_RS00720	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IBG28_RS00785	COG2962	Rard protein
IBG28_RS00810	COG4372	Transposase
IBG28_RS00825	COG4584	PFAM Integrase catalytic
IBG28_RS00830	COG1484	DNA-dependent DNA replication
IBG28_RS00850	COG2885	chlorophyll binding
IBG28_RS00920	COG0583	DNA-binding transcription factor activity
IBG28_RS00945	COG3842	ATPase activity
IBG28_RS00955	COG1609	Transcriptional regulator
IBG28_RS00960	COG0483	inositol monophosphate 1-phosphatase activity
IBG28_RS00965	COG3706	GGDEF domain
IBG28_RS00970	COG1451	nucleotide metabolic process
IBG28_RS00990	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IBG28_RS01000	COG1309	transcriptional regulator
IBG28_RS01020	COG0513	Belongs to the DEAD box helicase family
IBG28_RS01030	COG2211	Major facilitator Superfamily
IBG28_RS01035	COG1472	Belongs to the glycosyl hydrolase 3 family
IBG28_RS01045	COG0754	glutathionylspermidine amidase activity
IBG28_RS01050	COG1902	pentaerythritol trinitrate reductase activity
IBG28_RS01055	COG0436	Aminotransferase
IBG28_RS01070	COG1301	dicarboxylic acid transport
IBG28_RS01080	COG1522	sequence-specific DNA binding
IBG28_RS01090	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IBG28_RS01095	COG1597	lipid kinase activity
IBG28_RS01095	COG1803	Methylglyoxal synthase
IBG28_RS01115	COG1234	tRNA 3'-trailer cleavage
IBG28_RS01120	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IBG28_RS01180	COG0583	DNA-binding transcription factor activity
IBG28_RS01210	COG0697	spore germination
IBG28_RS01225	COG0477	Major facilitator Superfamily
IBG28_RS01245	COG1522	sequence-specific DNA binding
IBG28_RS01250	COG2814	Major facilitator Superfamily
IBG28_RS01275	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IBG28_RS01285	COG1280	lysine exporter protein (LysE YggA)
IBG28_RS01295	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IBG28_RS01305	COG2095	MarC family integral membrane protein
IBG28_RS01315	COG0735	belongs to the Fur family
IBG28_RS01320	COG1121	(ABC) transporter
IBG28_RS01325	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IBG28_RS01335	COG2832	Protein of unknown function (DUF454)
IBG28_RS01360	COG3220	belongs to the UPF0276 family
IBG28_RS01375	COG1595	DNA-templated transcription, initiation
IBG28_RS01380	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IBG28_RS01415	COG0778	Nitroreductase
IBG28_RS01420	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
IBG28_RS01425	COG0840	transmembrane signaling receptor activity
IBG28_RS01450	COG3046	protein related to deoxyribodipyrimidine photolyase
IBG28_RS01455	COG0415	Belongs to the DNA photolyase family
IBG28_RS01460	COG0415	Belongs to the DNA photolyase family
IBG28_RS01465	COG2824	Alkylphosphonate utilization operon protein PhnA
IBG28_RS01475	COG2814	Major facilitator Superfamily
IBG28_RS01480	COG1733	regulation of RNA biosynthetic process
IBG28_RS01495	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
IBG28_RS01515	COG2161	toxin-antitoxin pair type II binding
IBG28_RS01525	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
IBG28_RS01535	COG3634	alkyl hydroperoxide reductase activity
IBG28_RS01545	COG3437	response regulator, receiver
IBG28_RS01550	COG0784	Response regulator, receiver
IBG28_RS01550	COG2205	protein histidine kinase activity
IBG28_RS01550	COG5002	protein histidine kinase activity
IBG28_RS01560	COG1984	allophanate hydrolase subunit 2
IBG28_RS01565	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
IBG28_RS01570	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
IBG28_RS01590	COG4336	lyase activity
IBG28_RS01595	COG0154	amidase activity
IBG28_RS01600	COG0583	DNA-binding transcription factor activity
IBG28_RS01610	COG1215	transferase activity, transferring glycosyl groups
IBG28_RS01625	COG2885	chlorophyll binding
IBG28_RS01630	COG3634	alkyl hydroperoxide reductase activity
IBG28_RS01640	COG3384	dioxygenase
IBG28_RS01675	COG0583	DNA-binding transcription factor activity
IBG28_RS01700	COG0395	ABC-type sugar transport system, permease component
IBG28_RS01710	COG3842	ATPase activity
IBG28_RS01715	COG3842	ATPase activity
IBG28_RS01720	COG3284	Transcriptional regulator
IBG28_RS01730	COG0583	DNA-binding transcription factor activity
IBG28_RS01765	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IBG28_RS01775	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
IBG28_RS01780	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
IBG28_RS01785	COG1842	Phage shock protein A
IBG28_RS01795	COG1983	PspC domain protein
IBG28_RS01805	COG1858	cytochrome C peroxidase
IBG28_RS01810	COG0840	transmembrane signaling receptor activity
IBG28_RS01820	COG0583	DNA-binding transcription factor activity
IBG28_RS01830	COG0783	Belongs to the Dps family
IBG28_RS01845	COG3850	Histidine kinase
IBG28_RS01845	COG0642	Histidine kinase
IBG28_RS01850	COG0745	RESPONSE REGULATOR receiver
IBG28_RS01855	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IBG28_RS01870	COG1846	Transcriptional regulator
IBG28_RS01875	COG1764	response to oxidative stress
IBG28_RS01890	COG2154	pterin-4-alpha-carbinolamine dehydratase
IBG28_RS01910	COG2207	Transcriptional regulator
IBG28_RS01915	COG3152	Membrane
IBG28_RS01925	COG3706	GGDEF domain
IBG28_RS01925	COG5001	Diguanylate cyclase
IBG28_RS01925	COG2203	Gaf domain
IBG28_RS01925	COG4251	negative regulation of phosphorylation
IBG28_RS01930	COG0583	DNA-binding transcription factor activity
IBG28_RS01960	COG5433	transposase activity
IBG28_RS01965	COG1309	transcriptional regulator
IBG28_RS01980	COG0765	amino acid transport
IBG28_RS01985	COG0765	amino acid transport
IBG28_RS02000	COG0154	amidase activity
IBG28_RS02010	COG0730	response to heat
IBG28_RS02015	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
IBG28_RS02040	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IBG28_RS02060	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IBG28_RS02065	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IBG28_RS02070	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IBG28_RS02095	COG1595	DNA-templated transcription, initiation
IBG28_RS02115	COG1953	Uracil, thiamine, allantoin
IBG28_RS02120	COG0531	amino acid
IBG28_RS02135	COG2207	Transcriptional regulator
IBG28_RS02170	COG0523	cobalamin synthesis protein
IBG28_RS02195	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IBG28_RS02220	COG0583	DNA-binding transcription factor activity
IBG28_RS02260	COG2706	6-phosphogluconolactonase activity
IBG28_RS02270	COG1012	belongs to the aldehyde dehydrogenase family
IBG28_RS02285	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
IBG28_RS02290	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IBG28_RS02295	COG0730	response to heat
IBG28_RS02305	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IBG28_RS02310	COG0583	DNA-binding transcription factor activity
IBG28_RS02335	COG2721	sulfolactate sulfo-lyase activity
IBG28_RS02340	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IBG28_RS02350	COG2186	Transcriptional regulator
IBG28_RS02370	COG4948	Mandelate Racemase Muconate Lactonizing
IBG28_RS02385	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
IBG28_RS02410	COG1678	Uncharacterized ACR, COG1678
IBG28_RS02415	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IBG28_RS02425	COG0540	Belongs to the ATCase OTCase family
IBG28_RS02430	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
IBG28_RS02440	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IBG28_RS02445	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IBG28_RS02455	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IBG28_RS02460	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IBG28_RS02475	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IBG28_RS02510	COG1653	transport
IBG28_RS02525	COG3842	ATPase activity
IBG28_RS02535	COG1349	DNA-binding transcription factor activity
IBG28_RS02545	COG2354	Protein conserved in bacteria
IBG28_RS02550	COG1414	Transcriptional regulator
IBG28_RS02555	COG0391	Required for morphogenesis under gluconeogenic growth conditions
IBG28_RS02565	COG3706	GGDEF domain
IBG28_RS02580	COG0189	ligase activity
IBG28_RS02580	COG4067	protein conserved in archaea
IBG28_RS02595	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IBG28_RS02600	COG1309	transcriptional regulator
IBG28_RS02605	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IBG28_RS02615	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IBG28_RS02620	COG2003	Belongs to the UPF0758 family
IBG28_RS02635	COG0227	Belongs to the bacterial ribosomal protein bL28 family
IBG28_RS02640	COG0267	Belongs to the bacterial ribosomal protein bL33 family
IBG28_RS02645	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
IBG28_RS02650	COG1744	ABC transporter substrate-binding protein PnrA-like
IBG28_RS02655	COG3845	ABC transporter
IBG28_RS02660	COG4603	Belongs to the binding-protein-dependent transport system permease family
IBG28_RS02665	COG1079	Belongs to the binding-protein-dependent transport system permease family
IBG28_RS02670	COG0295	cytidine deaminase activity
IBG28_RS02675	COG3180	Ammonia monooxygenase
IBG28_RS02680	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IBG28_RS02705	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IBG28_RS02710	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
IBG28_RS02715	COG4208	sulfate ABC transporter
IBG28_RS02720	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
IBG28_RS02725	COG4150	thiosulfate binding
IBG28_RS02745	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
IBG28_RS02775	COG3344	reverse transcriptase
IBG28_RS02785	COG4974	Belongs to the 'phage' integrase family
IBG28_RS02800	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
IBG28_RS02805	COG0733	neurotransmitter:sodium symporter activity
IBG28_RS02810	COG2867	negative regulation of translational initiation
IBG28_RS02815	COG2914	Belongs to the UPF0125 (RnfH) family
IBG28_RS02830	COG0497	DNA recombination
IBG28_RS02835	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IBG28_RS02840	COG0443	Heat shock 70 kDa protein
IBG28_RS02845	COG0484	heat shock protein binding
IBG28_RS02850	COG0572	uridine kinase
IBG28_RS02870	COG0583	DNA-binding transcription factor activity
IBG28_RS02875	COG0730	response to heat
IBG28_RS02890	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IBG28_RS02910	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IBG28_RS02920	COG0678	peroxiredoxin activity
IBG28_RS02920	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IBG28_RS02935	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IBG28_RS02940	COG2159	amidohydrolase
IBG28_RS02945	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IBG28_RS02980	COG0439	Biotin carboxylase
IBG28_RS02990	COG0667	Aldo Keto reductase
IBG28_RS03000	COG0583	DNA-binding transcription factor activity
IBG28_RS03005	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IBG28_RS03015	COG0679	Auxin Efflux Carrier
IBG28_RS03020	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
IBG28_RS03030	COG0583	DNA-binding transcription factor activity
IBG28_RS03035	COG1082	Xylose isomerase domain protein TIM barrel
IBG28_RS03035	COG3185	4-Hydroxyphenylpyruvate dioxygenase
IBG28_RS03040	COG0840	transmembrane signaling receptor activity
IBG28_RS03060	COG0006	proline dipeptidase activity
IBG28_RS03085	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
IBG28_RS03110	COG0402	S-adenosylhomocysteine deaminase activity
IBG28_RS03115	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
IBG28_RS03120	COG2986	histidine ammonia-lyase
IBG28_RS03125	COG1228	amidohydrolase
IBG28_RS03150	COG0583	DNA-binding transcription factor activity
IBG28_RS03170	COG4771	TonB-dependent receptor
IBG28_RS03175	COG2207	Transcriptional regulator
IBG28_RS03185	COG1476	TRANSCRIPTIONal
IBG28_RS03190	COG1609	Transcriptional regulator
IBG28_RS03195	COG1486	melibiose metabolic process
IBG28_RS03205	COG0395	ABC-type sugar transport system, permease component
IBG28_RS03210	COG1175	transmembrane transport
IBG28_RS03225	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IBG28_RS03230	COG0798	PFAM Bile acid sodium symporter
IBG28_RS03235	COG0640	Transcriptional regulator
IBG28_RS03250	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IBG28_RS03255	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IBG28_RS03265	COG5001	Diguanylate cyclase
IBG28_RS03265	COG5002	protein histidine kinase activity
IBG28_RS03265	COG3447	MASE1 domain protein
IBG28_RS03280	COG0823	Involved in the tonB-independent uptake of proteins
IBG28_RS03285	COG1175	transmembrane transport
IBG28_RS03290	COG0395	ABC-type sugar transport system, permease component
IBG28_RS03295	COG3842	ATPase activity
IBG28_RS03300	COG1653	transport
IBG28_RS03305	COG1028	Short-chain dehydrogenase reductase Sdr
IBG28_RS03310	COG1414	Transcriptional regulator
IBG28_RS03315	COG1917	Cupin 2, conserved barrel domain protein
IBG28_RS03335	COG2130	NADP-dependent
IBG28_RS03340	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IBG28_RS03350	COG1280	lysine exporter protein (LysE YggA)
IBG28_RS03370	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
IBG28_RS03380	COG2204	response regulator
IBG28_RS03385	COG3706	GGDEF domain
IBG28_RS03390	COG0405	Gamma-glutamyltransferase
IBG28_RS03400	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IBG28_RS03415	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IBG28_RS03420	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IBG28_RS03430	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IBG28_RS03435	COG1444	tRNA N-acetyltransferase activity
IBG28_RS03440	COG2079	MmgE PrpD family protein
IBG28_RS03445	COG0372	Belongs to the citrate synthase family
IBG28_RS03450	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
IBG28_RS03455	COG1802	Transcriptional regulator
IBG28_RS03485	COG0423	glycine-tRNA ligase activity
IBG28_RS03490	COG4771	TonB-dependent receptor
IBG28_RS03495	COG0583	DNA-binding transcription factor activity
IBG28_RS03530	COG0583	DNA-binding transcription factor activity
IBG28_RS03535	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IBG28_RS03550	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IBG28_RS03560	COG0625	glutathione transferase activity
IBG28_RS03570	COG0583	DNA-binding transcription factor activity
IBG28_RS03575	COG2814	Major facilitator Superfamily
IBG28_RS03580	COG0656	L-ascorbic acid biosynthetic process
IBG28_RS03585	COG0438	transferase activity, transferring glycosyl groups
IBG28_RS03590	COG3700	Belongs to the class B bacterial acid phosphatase family
IBG28_RS03600	COG2026	Addiction module toxin, RelE StbE family
IBG28_RS03615	COG1119	ATPase activity
IBG28_RS03620	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IBG28_RS03630	COG1840	ABC-type Fe3 transport system, periplasmic component
IBG28_RS03640	COG2814	Major facilitator Superfamily
IBG28_RS03655	COG4335	DNA alkylation repair
IBG28_RS03690	COG3048	D-serine ammonia-lyase activity
IBG28_RS03695	COG0583	DNA-binding transcription factor activity
IBG28_RS03705	COG0601	transmembrane transport
IBG28_RS03715	COG0444	Belongs to the ABC transporter superfamily
IBG28_RS03720	COG4608	Belongs to the ABC transporter superfamily
IBG28_RS03740	COG2515	1-aminocyclopropane-1-carboxylate deaminase
IBG28_RS03745	COG0840	transmembrane signaling receptor activity
IBG28_RS03750	COG1522	sequence-specific DNA binding
IBG28_RS03755	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
IBG28_RS03760	COG2116	formate transmembrane transporter activity
IBG28_RS03765	COG0515	serine threonine protein kinase
IBG28_RS03765	COG2815	serine threonine protein kinase
IBG28_RS03770	COG0058	SHG alpha-glucan phosphorylase activity
IBG28_RS03780	COG0346	lactoylglutathione lyase activity
IBG28_RS03790	COG3706	GGDEF domain
IBG28_RS03790	COG2203	Gaf domain
IBG28_RS03790	COG4251	negative regulation of phosphorylation
IBG28_RS03790	COG5001	Diguanylate cyclase
IBG28_RS03795	COG3214	Protein conserved in bacteria
IBG28_RS03805	COG0644	oxidoreductase
IBG28_RS03830	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
IBG28_RS03835	COG4952	isomerase
IBG28_RS03840	COG3347	Dehydrogenase
IBG28_RS03840	COG1028	Short-chain dehydrogenase reductase Sdr
IBG28_RS03850	COG1879	ABC-type sugar transport system periplasmic component
IBG28_RS03855	COG1129	ABC transporter
IBG28_RS03860	COG1172	Belongs to the binding-protein-dependent transport system permease family
IBG28_RS03870	COG3254	rhamnose metabolic process
IBG28_RS03880	COG5654	RES domain protein
IBG28_RS03890	COG3250	beta-galactosidase activity
IBG28_RS03900	COG1175	transmembrane transport
IBG28_RS03905	COG0395	ABC-type sugar transport system, permease component
IBG28_RS03950	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IBG28_RS03955	COG1609	Transcriptional regulator
IBG28_RS03970	COG3416	Protein conserved in bacteria
IBG28_RS03985	COG0697	spore germination
IBG28_RS03995	COG0626	cystathionine gamma-synthase activity
IBG28_RS04000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IBG28_RS04005	COG0765	amino acid transport
IBG28_RS04015	COG0583	DNA-binding transcription factor activity
IBG28_RS04020	COG3141	response to X-ray
IBG28_RS04050	COG1794	racemase activity, acting on amino acids and derivatives
IBG28_RS04055	COG0454	-acetyltransferase
IBG28_RS04065	COG3530	Putative quorum-sensing-regulated virulence factor
IBG28_RS04070	COG0583	DNA-binding transcription factor activity
IBG28_RS04095	COG0019	diaminopimelate decarboxylase activity
IBG28_RS04100	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IBG28_RS04110	COG1011	Hydrolase
IBG28_RS04120	COG0739	heme binding
IBG28_RS04175	COG1522	sequence-specific DNA binding
IBG28_RS04180	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IBG28_RS04185	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IBG28_RS04190	COG1803	Methylglyoxal synthase
IBG28_RS04195	COG0469	pyruvate kinase activity
IBG28_RS04200	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IBG28_RS04210	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IBG28_RS04215	COG1737	Transcriptional regulator
IBG28_RS04220	COG0510	thiamine kinase activity
IBG28_RS04225	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IBG28_RS04230	COG0354	folic acid binding
IBG28_RS04235	COG3437	response regulator, receiver
IBG28_RS04240	COG2205	protein histidine kinase activity
IBG28_RS04240	COG0784	Response regulator, receiver
IBG28_RS04240	COG2198	Histidine kinase
IBG28_RS04245	COG1070	Carbohydrate kinase
IBG28_RS04250	COG2169	Transcriptional regulator
IBG28_RS04255	COG0246	Mannitol dehydrogenase
IBG28_RS04260	COG3842	ATPase activity
IBG28_RS04270	COG1175	transmembrane transport
IBG28_RS04305	COG3026	antisigma factor binding
IBG28_RS04315	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IBG28_RS04325	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IBG28_RS04325	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
IBG28_RS04350	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
IBG28_RS04355	COG0384	phenazine biosynthesis protein PhzF
IBG28_RS04380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IBG28_RS04405	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
IBG28_RS04420	COG2988	succinylglutamate desuccinylase activity
IBG28_RS04430	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
IBG28_RS04430	COG0517	IMP dehydrogenase activity
IBG28_RS04435	COG2877	3-deoxy-8-phosphooctulonate synthase activity
IBG28_RS04440	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
IBG28_RS04445	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
IBG28_RS04460	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IBG28_RS04480	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
IBG28_RS04485	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IBG28_RS04510	COG0583	DNA-binding transcription factor activity
IBG28_RS04530	COG1742	UPF0060 membrane protein
IBG28_RS04535	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IBG28_RS04540	COG0142	geranyltranstransferase activity
IBG28_RS04545	COG1722	exodeoxyribonuclease VII activity
IBG28_RS04550	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
IBG28_RS04560	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
IBG28_RS04575	COG3272	Protein of unknown function (DUF1722)
IBG28_RS04580	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
IBG28_RS04585	COG0789	Transcriptional regulator
IBG28_RS04595	COG0733	neurotransmitter:sodium symporter activity
IBG28_RS04605	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IBG28_RS04610	COG1917	Cupin 2, conserved barrel domain protein
IBG28_RS04620	COG0527	aspartate kinase activity
IBG28_RS04660	COG0494	nUDIX hydrolase
IBG28_RS04670	COG1917	Cupin 2, conserved barrel domain protein
IBG28_RS04670	COG2207	Transcriptional regulator
IBG28_RS04775	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IBG28_RS04780	COG3501	Rhs element vgr protein
IBG28_RS04845	COG3829	transcription factor binding
IBG28_RS04875	COG3501	Rhs element vgr protein
IBG28_RS04910	COG4372	Transposase
IBG28_RS04945	COG1285	pathogenesis
IBG28_RS04950	COG3706	GGDEF domain
IBG28_RS04955	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
IBG28_RS04965	COG3047	cAMP biosynthetic process
IBG28_RS04970	COG1418	mRNA catabolic process
IBG28_RS04990	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IBG28_RS05000	COG0297	glycogen (starch) synthase activity
IBG28_RS05005	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IBG28_RS05010	COG0307	riboflavin synthase, alpha
IBG28_RS05015	COG0481	GTPase activity
IBG28_RS05025	COG0571	ribonuclease III activity
IBG28_RS05030	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IBG28_RS05035	COG1381	Involved in DNA repair and RecF pathway recombination
IBG28_RS05040	COG0736	holo-[acyl-carrier-protein] synthase activity
IBG28_RS05045	COG0784	Response regulator, receiver
IBG28_RS05045	COG2205	protein histidine kinase activity
IBG28_RS05045	COG5002	protein histidine kinase activity
IBG28_RS05060	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IBG28_RS05065	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IBG28_RS05070	COG3956	TIGRFAM MazG family protein
IBG28_RS05075	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
IBG28_RS05080	COG0563	adenylate kinase activity
IBG28_RS05085	COG1214	PFAM Peptidase M22, glycoprotease
IBG28_RS05090	COG1968	undecaprenyl-diphosphatase activity
IBG28_RS05095	COG0742	ribosomal rna small subunit methyltransferase
IBG28_RS05100	COG2900	Belongs to the SlyX family
IBG28_RS05105	COG1278	Cold shock
IBG28_RS05110	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IBG28_RS05115	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
IBG28_RS05130	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IBG28_RS05140	COG1393	Belongs to the ArsC family
IBG28_RS05145	COG2171	N-acyltransferase activity
IBG28_RS05160	COG0024	Methionine aminopeptidase
IBG28_RS05165	COG0052	Belongs to the universal ribosomal protein uS2 family
IBG28_RS05170	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IBG28_RS05175	COG0528	UMP kinase activity
IBG28_RS05180	COG0233	cytoplasmic translational termination
IBG28_RS05185	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IBG28_RS05195	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
IBG28_RS05205	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IBG28_RS05215	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IBG28_RS05220	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IBG28_RS05225	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IBG28_RS05230	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IBG28_RS05235	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IBG28_RS05240	COG0587	DNA-directed DNA polymerase activity
IBG28_RS05245	COG0825	malonyl-CoA metabolic process
IBG28_RS05250	COG0037	tRNA processing
IBG28_RS05260	COG1566	PFAM secretion protein HlyD family protein
IBG28_RS05300	COG0148	phosphopyruvate hydratase activity
IBG28_RS05320	COG0585	pseudouridine synthase activity
IBG28_RS05325	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
IBG28_RS05330	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
IBG28_RS05355	COG0560	Phosphoserine phosphatase
IBG28_RS05355	COG3830	Belongs to the UPF0237 family
IBG28_RS05360	COG0583	DNA-binding transcription factor activity
IBG28_RS05375	COG0521	Mo-molybdopterin cofactor biosynthetic process
IBG28_RS05380	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IBG28_RS05385	COG1946	Acyl-CoA thioesterase
IBG28_RS05400	COG0028	Belongs to the TPP enzyme family
IBG28_RS05410	COG1522	sequence-specific DNA binding
IBG28_RS05425	COG1854	S-ribosylhomocysteine lyase activity
IBG28_RS05430	COG0531	amino acid
IBG28_RS05445	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
IBG28_RS05450	COG1183	phosphatidylcholine synthase activity
IBG28_RS05455	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IBG28_RS05490	COG0583	DNA-binding transcription factor activity
IBG28_RS05505	COG1902	pentaerythritol trinitrate reductase activity
IBG28_RS05505	COG0446	pyridine nucleotide-disulphide oxidoreductase
IBG28_RS05515	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IBG28_RS05520	COG3021	interspecies interaction between organisms
IBG28_RS05535	COG0719	Fe-S assembly protein
IBG28_RS05540	COG0396	ATPase activity
IBG28_RS05545	COG0719	Fe-S assembly protein
IBG28_RS05550	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IBG28_RS05555	COG0316	Belongs to the HesB IscA family
IBG28_RS05565	COG2166	iron-sulfur cluster assembly
IBG28_RS05575	COG0105	UTP biosynthetic process
IBG28_RS05580	COG0820	rRNA (adenine-C2-)-methyltransferase activity
IBG28_RS05595	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
IBG28_RS05600	COG0124	histidyl-tRNA synthetase
IBG28_RS05610	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IBG28_RS05615	COG1160	GTP binding
IBG28_RS05620	COG0189	ligase activity
IBG28_RS05635	COG1032	radical SAM domain protein
IBG28_RS05640	COG0500	methyltransferase
IBG28_RS05705	COG0019	diaminopimelate decarboxylase activity
IBG28_RS05715	COG0840	transmembrane signaling receptor activity
IBG28_RS05720	COG0443	Heat shock 70 kDa protein
IBG28_RS05730	COG2223	nitrite transmembrane transporter activity
IBG28_RS05745	COG0583	DNA-binding transcription factor activity
IBG28_RS05750	COG2814	Major facilitator Superfamily
IBG28_RS05760	COG0494	nUDIX hydrolase
IBG28_RS05775	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
IBG28_RS05780	COG0456	acetyltransferase
IBG28_RS05825	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
IBG28_RS05830	COG0557	exoribonuclease II activity
IBG28_RS05835	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IBG28_RS05840	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
IBG28_RS05855	COG2860	membrane
IBG28_RS05900	COG1309	transcriptional regulator
IBG28_RS05905	COG0784	Response regulator, receiver
IBG28_RS05905	COG2205	protein histidine kinase activity
IBG28_RS05920	COG1047	Peptidyl-prolyl cis-trans
IBG28_RS05930	COG1573	uracil-dna glycosylase
IBG28_RS05935	COG2153	protein acetylation
IBG28_RS05955	COG1522	sequence-specific DNA binding
IBG28_RS05960	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IBG28_RS05965	COG0778	Nitroreductase
IBG28_RS06010	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IBG28_RS06020	COG0179	Fumarylacetoacetate (FAA) hydrolase
IBG28_RS06030	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IBG28_RS06040	COG0641	radical SAM
IBG28_RS06105	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IBG28_RS06110	COG1028	Short-chain dehydrogenase reductase Sdr
IBG28_RS06120	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IBG28_RS06150	COG1522	sequence-specific DNA binding
IBG28_RS06160	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IBG28_RS06175	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IBG28_RS06210	COG1607	acyl-coa hydrolase
IBG28_RS06220	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
IBG28_RS06245	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
IBG28_RS06250	COG1074	ATP-dependent DNA helicase activity
IBG28_RS06255	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IBG28_RS06270	COG0835	chemotaxis
IBG28_RS06275	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IBG28_RS06285	COG0492	ferredoxin-NADP+ reductase activity
IBG28_RS06290	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IBG28_RS06295	COG0776	regulation of translation
IBG28_RS06305	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
IBG28_RS06310	COG0284	orotidine-5'-phosphate decarboxylase activity
IBG28_RS06315	COG1555	photosystem II stabilization
IBG28_RS06320	COG0659	secondary active sulfate transmembrane transporter activity
IBG28_RS06325	COG0556	nucleotide-excision repair
IBG28_RS06340	COG2197	response regulator
IBG28_RS06345	COG2205	protein histidine kinase activity
IBG28_RS06345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IBG28_RS06375	COG1741	Belongs to the pirin family
IBG28_RS06380	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
IBG28_RS06390	COG4774	siderophore transport
IBG28_RS06395	COG1120	ATPase activity
IBG28_RS06400	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IBG28_RS06405	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IBG28_RS06425	COG1850	ribulose-bisphosphate carboxylase activity
IBG28_RS06430	COG0287	Prephenate dehydrogenase
IBG28_RS06435	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IBG28_RS06445	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
IBG28_RS06445	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IBG28_RS06450	COG1349	DNA-binding transcription factor activity
IBG28_RS06455	COG1879	ABC-type sugar transport system periplasmic component
IBG28_RS06460	COG1172	Belongs to the binding-protein-dependent transport system permease family
IBG28_RS06465	COG1129	ABC transporter
IBG28_RS06495	COG1349	DNA-binding transcription factor activity
IBG28_RS06515	COG3002	Belongs to the UPF0753 family
IBG28_RS06520	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IBG28_RS06525	COG0583	DNA-binding transcription factor activity
IBG28_RS06540	COG0508	dehydrogenase complex catalyzes the overall conversion of
IBG28_RS06550	COG3327	negative regulation of DNA-templated transcription, initiation
IBG28_RS06560	COG1024	Enoyl-CoA hydratase
IBG28_RS06565	COG1024	Enoyl-CoA hydratase
IBG28_RS06570	COG1250	3-hydroxyacyl-CoA dehydrogenase
IBG28_RS06575	COG2050	protein possibly involved in aromatic compounds catabolism
IBG28_RS06580	COG0183	Belongs to the thiolase family
IBG28_RS06590	COG3396	Phenylacetate-CoA oxygenase
IBG28_RS06595	COG3460	Phenylacetate-CoA oxygenase
IBG28_RS06600	COG3396	Phenylacetate-CoA oxygenase
IBG28_RS06605	COG2151	metal-sulfur cluster biosynthetic enzyme
IBG28_RS06610	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IBG28_RS06615	COG1012	belongs to the aldehyde dehydrogenase family
IBG28_RS06615	COG2030	dehydratase
IBG28_RS06640	COG3344	reverse transcriptase
IBG28_RS06645	COG0235	Class ii aldolase
IBG28_RS06650	COG0583	DNA-binding transcription factor activity
IBG28_RS06655	COG4628	conserved protein (DUF2132)
IBG28_RS06660	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
IBG28_RS06665	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
IBG28_RS06670	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
IBG28_RS06675	COG2205	protein histidine kinase activity
IBG28_RS06680	COG0745	RESPONSE REGULATOR receiver
IBG28_RS06685	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IBG28_RS06685	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IBG28_RS06690	COG1063	alcohol dehydrogenase
IBG28_RS06775	COG0583	DNA-binding transcription factor activity
IBG28_RS06780	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IBG28_RS06785	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IBG28_RS06790	COG0183	Belongs to the thiolase family
IBG28_RS06795	COG2031	fatty acid transporter
IBG28_RS06820	COG0583	DNA-binding transcription factor activity
IBG28_RS06835	COG0483	inositol monophosphate 1-phosphatase activity
IBG28_RS06840	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IBG28_RS06860	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
IBG28_RS06870	COG0183	Belongs to the thiolase family
IBG28_RS06875	COG1024	Enoyl-CoA hydratase
IBG28_RS06885	COG1960	acyl-CoA dehydrogenase activity
IBG28_RS06890	COG3320	Male sterility
IBG28_RS06890	COG1022	Amp-dependent synthetase and ligase
IBG28_RS06910	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IBG28_RS06915	COG0243	molybdopterin cofactor binding
IBG28_RS06920	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IBG28_RS06925	COG0739	heme binding
IBG28_RS06945	COG2226	methyltransferase
IBG28_RS06950	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IBG28_RS06960	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
IBG28_RS06965	COG1605	Chorismate mutase
IBG28_RS06965	COG0077	Prephenate dehydratase
IBG28_RS06980	COG0596	Alpha beta hydrolase
IBG28_RS06985	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IBG28_RS06990	COG0633	Ferredoxin
IBG28_RS06995	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IBG28_RS07000	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IBG28_RS07020	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
IBG28_RS07025	COG0537	adenosine 5'-monophosphoramidase activity
IBG28_RS07040	COG0151	Belongs to the GarS family
IBG28_RS07045	COG0138	bifunctional purine biosynthesis protein purh
IBG28_RS07055	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IBG28_RS07065	COG2264	protein methyltransferase activity
IBG28_RS07075	COG0511	ligase activity, forming carbon-carbon bonds
IBG28_RS07080	COG4232	protein-disulfide reductase activity
IBG28_RS07120	COG0232	Belongs to the dGTPase family. Type 2 subfamily
IBG28_RS07175	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IBG28_RS07175	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
IBG28_RS07185	COG0693	protein deglycase activity
IBG28_RS07195	COG3038	cytochrome b561
IBG28_RS07200	COG1187	pseudouridine synthase activity
IBG28_RS07210	COG2995	paraquat-inducible protein a
IBG28_RS07215	COG3008	intermembrane lipid transfer
IBG28_RS07215	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IBG28_RS07225	COG0646	methionine synthase
IBG28_RS07225	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IBG28_RS07230	COG0596	Alpha beta hydrolase
IBG28_RS07245	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
IBG28_RS07260	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IBG28_RS07270	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IBG28_RS07280	COG1466	dna polymerase III delta subunit
IBG28_RS07290	COG0495	leucyl-tRNA aminoacylation
IBG28_RS07300	COG0815	Transfers the fatty acyl group on membrane lipoproteins
IBG28_RS07305	COG4535	Mg2 and Co2 transporter CorC
IBG28_RS07310	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IBG28_RS07315	COG1702	phosphate starvation-inducible protein PhoH
IBG28_RS07320	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IBG28_RS07345	COG0123	including yeast histone deacetylase and acetoin utilization protein
IBG28_RS07390	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IBG28_RS07395	COG1739	Uncharacterized protein family UPF0029
IBG28_RS07425	COG0793	Belongs to the peptidase S41A family
IBG28_RS07430	COG1362	aminopeptidase activity
IBG28_RS07435	COG1538	Outer membrane efflux protein
IBG28_RS07450	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IBG28_RS07450	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
IBG28_RS07455	COG0840	transmembrane signaling receptor activity
IBG28_RS07465	COG0716	FMN binding
IBG28_RS07490	COG0745	RESPONSE REGULATOR receiver
IBG28_RS07495	COG2205	protein histidine kinase activity
IBG28_RS07500	COG0204	Acyl-transferase
IBG28_RS07505	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IBG28_RS07510	COG0217	transcriptional regulatory protein
IBG28_RS07525	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
IBG28_RS07540	COG1028	Short-chain dehydrogenase reductase Sdr
IBG28_RS07545	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IBG28_RS07555	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IBG28_RS07565	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
IBG28_RS07570	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
IBG28_RS07590	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IBG28_RS07595	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IBG28_RS07600	COG0799	negative regulation of ribosome biogenesis
IBG28_RS07605	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IBG28_RS07610	COG0768	penicillin binding
IBG28_RS07615	COG0772	Belongs to the SEDS family
IBG28_RS07620	COG2951	lytic endotransglycosylase activity
IBG28_RS07625	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IBG28_RS07630	COG1686	Belongs to the peptidase S11 family
IBG28_RS07635	COG2921	Belongs to the UPF0250 family
IBG28_RS07640	COG0321	lipoyl(octanoyl) transferase activity
IBG28_RS07645	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IBG28_RS07650	COG1166	arginine decarboxylase activity
IBG28_RS07655	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IBG28_RS07660	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IBG28_RS07675	COG2193	ferroxidase activity
IBG28_RS07700	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
IBG28_RS07725	COG5433	transposase activity
IBG28_RS07745	COG2197	response regulator
IBG28_RS07750	COG3707	response regulator
IBG28_RS07755	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IBG28_RS07755	COG1116	anion transmembrane transporter activity
IBG28_RS07760	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IBG28_RS07765	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IBG28_RS07770	COG1116	anion transmembrane transporter activity
IBG28_RS07775	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IBG28_RS07780	COG2146	nitrite reductase [NAD(P)H] activity
IBG28_RS07780	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IBG28_RS07790	COG0243	molybdopterin cofactor binding
IBG28_RS07800	COG0746	molybdenum cofactor guanylyltransferase activity
IBG28_RS07810	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IBG28_RS07815	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
IBG28_RS07835	COG2009	succinate dehydrogenase
IBG28_RS07840	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
IBG28_RS07845	COG1053	succinate dehydrogenase
IBG28_RS07850	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IBG28_RS07870	COG0045	succinate-CoA ligase (ADP-forming) activity
IBG28_RS07885	COG0579	oxidoreductase
IBG28_RS07905	COG3290	protein histidine kinase activity
IBG28_RS07920	COG2201	protein-glutamate methylesterase activity
IBG28_RS07925	COG4191	Histidine kinase
IBG28_RS07930	COG2186	Transcriptional regulator
IBG28_RS07940	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
IBG28_RS07955	COG1904	glucuronate isomerase
IBG28_RS07960	COG0246	Mannitol dehydrogenase
IBG28_RS07965	COG1312	Catalyzes the dehydration of D-mannonate
IBG28_RS07975	COG2207	Transcriptional regulator
IBG28_RS07985	COG1609	Transcriptional regulator
IBG28_RS07995	COG1175	transmembrane transport
IBG28_RS08000	COG0395	ABC-type sugar transport system, permease component
IBG28_RS08010	COG3842	ATPase activity
IBG28_RS08015	COG1280	lysine exporter protein (LysE YggA)
IBG28_RS08025	COG0657	acetylesterase activity
IBG28_RS08040	COG3041	Addiction module toxin RelE StbE family
IBG28_RS08060	COG0404	The glycine cleavage system catalyzes the degradation of glycine
IBG28_RS08060	COG0446	pyridine nucleotide-disulphide oxidoreductase
IBG28_RS08080	COG0277	FAD linked oxidase domain protein
IBG28_RS08085	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
IBG28_RS08115	COG0004	ammonium transporteR
IBG28_RS08125	COG1234	tRNA 3'-trailer cleavage
IBG28_RS08135	COG2207	Transcriptional regulator
IBG28_RS08140	COG2807	transmembrane transport
IBG28_RS08150	COG0402	S-adenosylhomocysteine deaminase activity
IBG28_RS08220	COG1917	Cupin 2, conserved barrel domain protein
IBG28_RS08220	COG2207	Transcriptional regulator
IBG28_RS08270	COG0589	response to stress
IBG28_RS08320	COG2814	Major facilitator Superfamily
IBG28_RS08325	COG0789	Transcriptional regulator
IBG28_RS08330	COG4213	ABC transporter substrate-binding protein
IBG28_RS08335	COG1129	ABC transporter
IBG28_RS08340	COG4214	carbohydrate transport
IBG28_RS08345	COG1070	Carbohydrate kinase
IBG28_RS08350	COG1609	Transcriptional regulator
IBG28_RS08350	COG2207	Transcriptional regulator
IBG28_RS08355	COG1609	Transcriptional regulator
IBG28_RS08360	COG1879	ABC-type sugar transport system periplasmic component
IBG28_RS08370	COG1129	ABC transporter
IBG28_RS08375	COG1172	Belongs to the binding-protein-dependent transport system permease family
IBG28_RS08380	COG4154	Belongs to the RbsD FucU family
IBG28_RS08385	COG2115	Belongs to the xylose isomerase family
IBG28_RS08405	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IBG28_RS08420	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IBG28_RS08425	COG1116	anion transmembrane transporter activity
IBG28_RS08440	COG0439	Biotin carboxylase
IBG28_RS08455	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IBG28_RS08465	COG0739	heme binding
IBG28_RS08470	COG0513	Belongs to the DEAD box helicase family
IBG28_RS08480	COG1187	pseudouridine synthase activity
IBG28_RS08495	COG1620	l-lactate permease
IBG28_RS08505	COG1115	amino acid carrier protein
IBG28_RS08520	COG2828	Protein conserved in bacteria
IBG28_RS08525	COG0583	DNA-binding transcription factor activity
IBG28_RS08530	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IBG28_RS08535	COG1368	sulfuric ester hydrolase activity
IBG28_RS08560	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IBG28_RS08570	COG1079	Belongs to the binding-protein-dependent transport system permease family
IBG28_RS08575	COG4603	Belongs to the binding-protein-dependent transport system permease family
IBG28_RS08580	COG3845	ABC transporter
IBG28_RS08590	COG0564	pseudouridine synthase activity
IBG28_RS08595	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
IBG28_RS08615	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IBG28_RS08620	COG0154	amidase activity
IBG28_RS08625	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IBG28_RS08630	COG1077	Cell shape determining protein MreB Mrl
IBG28_RS08635	COG1792	Involved in formation and maintenance of cell shape
IBG28_RS08640	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
IBG28_RS08645	COG0424	maF-like protein
IBG28_RS08665	COG3028	Belongs to the UPF0307 family
IBG28_RS08670	COG2239	Acts as a magnesium transporter
IBG28_RS08690	COG1137	ATPase activity
IBG28_RS08695	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
IBG28_RS08710	COG1127	ABC transporter
IBG28_RS08715	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IBG28_RS08720	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IBG28_RS08730	COG0271	Belongs to the BolA IbaG family
IBG28_RS08735	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IBG28_RS08740	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
IBG28_RS08745	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IBG28_RS08755	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IBG28_RS08760	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IBG28_RS08770	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IBG28_RS08775	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IBG28_RS08780	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IBG28_RS08785	COG0625	glutathione transferase activity
IBG28_RS08790	COG2969	positive regulation of protein catabolic process
IBG28_RS08800	COG0792	nuclease activity
IBG28_RS08810	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IBG28_RS08815	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
IBG28_RS08820	COG0352	thiamine-phosphate diphosphorylase activity
IBG28_RS08830	COG2022	thiamine diphosphate biosynthetic process
IBG28_RS08835	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
IBG28_RS08845	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
IBG28_RS08850	COG4989	oxidoreductase activity
IBG28_RS08860	COG4999	Histidine kinase
IBG28_RS08860	COG2205	protein histidine kinase activity
IBG28_RS08860	COG3437	response regulator, receiver
IBG28_RS08860	COG3850	Histidine kinase
IBG28_RS08865	COG3437	response regulator, receiver
IBG28_RS08870	COG3012	SEC-C Motif Domain Protein
IBG28_RS08875	COG2925	Exonuclease
IBG28_RS08880	COG0628	permease
IBG28_RS08890	COG0418	dihydroorotase activity
IBG28_RS08910	COG0326	Molecular chaperone. Has ATPase activity
IBG28_RS08915	COG1793	dna ligase
IBG28_RS08920	COG0596	Alpha beta hydrolase
IBG28_RS08925	COG0640	Transcriptional regulator
IBG28_RS08930	COG0708	Exodeoxyribonuclease III
IBG28_RS08940	COG2195	Cleaves the N-terminal amino acid of tripeptides
IBG28_RS08955	COG2161	toxin-antitoxin pair type II binding
IBG28_RS08975	COG0420	3'-5' exonuclease activity
IBG28_RS08980	COG0419	ATPase involved in DNA repair
IBG28_RS08985	COG0850	regulation of cytokinetic process
IBG28_RS08990	COG2894	cell division
IBG28_RS08995	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
IBG28_RS09000	COG1858	cytochrome C peroxidase
IBG28_RS09005	COG0667	Aldo Keto reductase
IBG28_RS09010	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IBG28_RS09025	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IBG28_RS09030	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
IBG28_RS09030	COG0316	Belongs to the HesB IscA family
IBG28_RS09040	COG0730	response to heat
IBG28_RS09045	COG0583	DNA-binding transcription factor activity
IBG28_RS09055	COG1393	Belongs to the ArsC family
IBG28_RS09060	COG0442	prolyl-tRNA aminoacylation
IBG28_RS09080	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
IBG28_RS09080	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
IBG28_RS09115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IBG28_RS09120	COG0765	amino acid transport
IBG28_RS09125	COG0765	amino acid transport
IBG28_RS09130	COG1126	abc transporter atp-binding protein
IBG28_RS09140	COG3135	benzoate transporter
IBG28_RS09160	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
IBG28_RS09165	COG0237	dephospho-CoA kinase activity
IBG28_RS09170	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
IBG28_RS09180	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IBG28_RS09195	COG0280	phosphate acetyltransferase
IBG28_RS09195	COG0857	belongs to the CobB CobQ family
IBG28_RS09200	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IBG28_RS09215	COG0508	dehydrogenase complex catalyzes the overall conversion of
IBG28_RS09220	COG2204	response regulator
IBG28_RS09345	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IBG28_RS09380	COG1175	transmembrane transport
IBG28_RS09385	COG0395	ABC-type sugar transport system, permease component
IBG28_RS09395	COG0129	dihydroxy-acid dehydratase activity
IBG28_RS09405	COG3734	2-keto-3-deoxy-galactonokinase
IBG28_RS09410	COG0800	Aldolase
IBG28_RS09425	COG1653	transport
IBG28_RS09435	COG0601	transmembrane transport
IBG28_RS09440	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IBG28_RS09445	COG4172	Belongs to the ABC transporter superfamily
IBG28_RS09455	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IBG28_RS09460	COG1522	sequence-specific DNA binding
IBG28_RS09465	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IBG28_RS09470	COG0513	Belongs to the DEAD box helicase family
IBG28_RS09480	COG2996	Protein conserved in bacteria
IBG28_RS09485	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IBG28_RS09490	COG1666	GTP binding
IBG28_RS09505	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IBG28_RS09510	COG0459	protein refolding
IBG28_RS09515	COG5001	Diguanylate cyclase
IBG28_RS09530	COG0135	phosphoribosylanthranilate isomerase activity
IBG28_RS09535	COG0133	tryptophan synthase activity
IBG28_RS09540	COG0159	tryptophan synthase activity
IBG28_RS09545	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IBG28_RS09550	COG0285	dihydrofolate synthase activity
IBG28_RS09560	COG1286	toxin biosynthetic process
IBG28_RS09585	COG0488	(ABC) transporter
IBG28_RS09595	COG0443	Heat shock 70 kDa protein
IBG28_RS09605	COG1120	ATPase activity
IBG28_RS09610	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IBG28_RS09615	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IBG28_RS09620	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
IBG28_RS09625	COG4608	Belongs to the ABC transporter superfamily
IBG28_RS09630	COG0444	Belongs to the ABC transporter superfamily
IBG28_RS09635	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IBG28_RS09640	COG0601	transmembrane transport
IBG28_RS09645	COG0747	negative chemotaxis
IBG28_RS09650	COG4948	Mandelate Racemase Muconate Lactonizing
IBG28_RS09665	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IBG28_RS09680	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IBG28_RS09680	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IBG28_RS09685	COG0509	glycine decarboxylation via glycine cleavage system
IBG28_RS09690	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IBG28_RS09695	COG0404	The glycine cleavage system catalyzes the degradation of glycine
IBG28_RS09700	COG3101	peptidyl-lysine hydroxylation
IBG28_RS09705	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IBG28_RS09715	COG0501	Belongs to the peptidase M48B family
IBG28_RS09720	COG0436	Aminotransferase
IBG28_RS09790	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IBG28_RS09795	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IBG28_RS09800	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IBG28_RS09810	COG0084	hydrolase, TatD family'
IBG28_RS09815	COG1067	ATP-dependent peptidase activity
IBG28_RS09840	COG1960	acyl-CoA dehydrogenase activity
IBG28_RS09850	COG1671	Belongs to the UPF0178 family
IBG28_RS09855	COG1252	NADH dehydrogenase
IBG28_RS09865	COG2217	Heavy metal translocating P-type atpase
IBG28_RS09870	COG2814	Major facilitator Superfamily
IBG28_RS09875	COG0659	secondary active sulfate transmembrane transporter activity
IBG28_RS09880	COG1011	Hydrolase
IBG28_RS09890	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IBG28_RS09915	COG2030	dehydratase
IBG28_RS09930	COG0425	Belongs to the sulfur carrier protein TusA family
IBG28_RS09945	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IBG28_RS09950	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IBG28_RS09960	COG0037	tRNA processing
IBG28_RS09965	COG3091	SprT-like family
IBG28_RS09980	COG0745	RESPONSE REGULATOR receiver
IBG28_RS09990	COG0271	Belongs to the BolA IbaG family
IBG28_RS10015	COG1090	epimerase
IBG28_RS10030	COG1011	Hydrolase
IBG28_RS10035	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
IBG28_RS10045	COG0784	Response regulator, receiver
IBG28_RS10045	COG0835	chemotaxis
IBG28_RS10055	COG0084	hydrolase, TatD family'
IBG28_RS10060	COG0417	DNA replication proofreading
IBG28_RS10065	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
IBG28_RS10070	COG4181	ATPase activity
IBG28_RS10080	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IBG28_RS10095	COG0023	Translation Initiation Factor
IBG28_RS10115	COG0582	viral genome integration into host DNA
IBG28_RS10135	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
IBG28_RS10140	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
IBG28_RS10145	COG1715	Restriction endonuclease
IBG28_RS10190	COG2003	Belongs to the UPF0758 family
IBG28_RS10220	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IBG28_RS10235	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
IBG28_RS10240	COG2885	chlorophyll binding
IBG28_RS10245	COG0823	Involved in the tonB-independent uptake of proteins
IBG28_RS10265	COG2255	four-way junction helicase activity
IBG28_RS10270	COG0632	four-way junction helicase activity
IBG28_RS10275	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
IBG28_RS10280	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IBG28_RS10305	COG0175	sulfate reduction
IBG28_RS10310	COG3344	reverse transcriptase
IBG28_RS10325	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IBG28_RS10355	COG0633	Ferredoxin
IBG28_RS10355	COG3217	Mosc domain protein beta barrel domain protein
IBG28_RS10360	COG0488	(ABC) transporter
IBG28_RS10370	COG0251	oxidation-reduction process
IBG28_RS10390	COG0308	aminopeptidase N
IBG28_RS10400	COG3139	Protein of unknown function (DUF1315)
IBG28_RS10410	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IBG28_RS10420	COG0741	lytic transglycosylase activity
IBG28_RS10425	COG0247	lactate metabolic process
IBG28_RS10425	COG0277	FAD linked oxidase domain protein
IBG28_RS10435	COG0033	Phosphoglucomutase
IBG28_RS10450	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IBG28_RS10455	COG0812	UDP-N-acetylmuramate dehydrogenase activity
IBG28_RS10460	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IBG28_RS10465	COG2835	tetraacyldisaccharide 4'-kinase activity
IBG28_RS10470	COG1663	tetraacyldisaccharide 4'-kinase activity
IBG28_RS10475	COG0848	biopolymer transport protein
IBG28_RS10480	COG0811	peptide transport
IBG28_RS10495	COG1136	(ABC) transporter
IBG28_RS10500	COG4591	ABC-type transport system involved in lipoprotein release permease component
IBG28_RS10505	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
IBG28_RS10515	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IBG28_RS10520	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IBG28_RS10525	COG0667	Aldo Keto reductase
IBG28_RS10540	COG0583	DNA-binding transcription factor activity
IBG28_RS10545	COG3119	arylsulfatase activity
IBG28_RS10555	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IBG28_RS10555	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IBG28_RS10560	COG0842	Transport permease protein
IBG28_RS10565	COG1131	(ABC) transporter
IBG28_RS10575	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IBG28_RS10580	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IBG28_RS10595	COG0416	fatty acid biosynthetic process
IBG28_RS10600	COG0333	Belongs to the bacterial ribosomal protein bL32 family
IBG28_RS10605	COG1399	metal-binding, possibly nucleic acid-binding protein
IBG28_RS10625	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IBG28_RS10625	COG0596	Alpha beta hydrolase
IBG28_RS10630	COG0588	phosphoglycerate mutase activity
IBG28_RS10640	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
IBG28_RS10645	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
IBG28_RS10655	COG1199	ATP-dependent helicase activity
IBG28_RS10660	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IBG28_RS10690	COG0589	response to stress
IBG28_RS10695	COG0215	cysteine-tRNA ligase activity
IBG28_RS10700	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IBG28_RS10710	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IBG28_RS10715	COG0602	queuosine metabolic process
IBG28_RS10720	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IBG28_RS10725	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IBG28_RS10750	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IBG28_RS10765	COG0473	3-isopropylmalate dehydrogenase activity
IBG28_RS10770	COG0066	3-isopropylmalate dehydratase activity
IBG28_RS10775	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IBG28_RS10790	COG0366	Alpha amylase catalytic
IBG28_RS10805	COG4783	chaperone-mediated protein folding
IBG28_RS10825	COG0314	molybdopterin synthase activity
IBG28_RS10835	COG0315	cyclic pyranopterin monophosphate synthase activity
IBG28_RS10840	COG2200	EAL domain
IBG28_RS10840	COG2203	Gaf domain
IBG28_RS10840	COG2199	diguanylate cyclase activity
IBG28_RS10845	COG0484	heat shock protein binding
IBG28_RS10855	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IBG28_RS10865	COG2866	Carboxypeptidase
IBG28_RS10875	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IBG28_RS10880	COG2095	MarC family integral membrane protein
IBG28_RS10895	COG1530	ribonuclease E activity
IBG28_RS10900	COG0659	secondary active sulfate transmembrane transporter activity
IBG28_RS10910	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IBG28_RS10935	COG0464	growth
IBG28_RS10945	COG4584	PFAM Integrase catalytic
IBG28_RS10950	COG1484	DNA-dependent DNA replication
IBG28_RS11025	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IBG28_RS11070	COG4372	Transposase
IBG28_RS11120	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IBG28_RS11130	COG0121	glutamine amidotransferase
IBG28_RS11140	COG0210	DNA helicase
IBG28_RS11150	COG4134	Bacterial extracellular solute-binding protein
IBG28_RS11155	COG4135	transport system, permease component
IBG28_RS11160	COG4136	ATPase activity
IBG28_RS11175	COG0625	glutathione transferase activity
IBG28_RS11200	COG1028	Short-chain dehydrogenase reductase Sdr
IBG28_RS11210	COG1473	amidohydrolase
IBG28_RS11215	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IBG28_RS11220	COG0006	proline dipeptidase activity
IBG28_RS11225	COG1012	belongs to the aldehyde dehydrogenase family
IBG28_RS11240	COG0386	Belongs to the glutathione peroxidase family
IBG28_RS11245	COG0431	NADPH-dependent FMN reductase
IBG28_RS11265	COG3314	Sporulation integral membrane protein YlbJ
IBG28_RS11300	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
IBG28_RS11305	COG0702	epimerase
IBG28_RS11310	COG2356	endonuclease I
IBG28_RS11330	COG3093	addiction module antidote protein HigA
IBG28_RS11390	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IBG28_RS11395	COG1045	serine acetyltransferase
IBG28_RS11400	COG2133	pyrroloquinoline quinone binding
IBG28_RS11410	COG2853	Lipoprotein
IBG28_RS11415	COG1643	Atp-dependent helicase
IBG28_RS11420	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IBG28_RS11455	COG0121	glutamine amidotransferase
IBG28_RS11465	COG2983	Belongs to the UPF0260 family
IBG28_RS11470	COG3100	YcgL domain-containing protein
IBG28_RS11480	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IBG28_RS11485	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IBG28_RS11495	COG1054	Belongs to the UPF0176 family
IBG28_RS11505	COG1061	Type III restriction enzyme res subunit
IBG28_RS11520	COG3148	PFAM DTW domain containing protein
IBG28_RS11535	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IBG28_RS11540	COG3081	Nucleoid-associated protein
IBG28_RS11610	COG4804	nuclease activity
IBG28_RS11635	COG2084	Dehydrogenase
IBG28_RS11640	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IBG28_RS11645	COG1349	DNA-binding transcription factor activity
IBG28_RS11650	COG2084	Dehydrogenase
IBG28_RS11655	COG3395	kinase activity
IBG28_RS11660	COG0235	Class ii aldolase
IBG28_RS11665	COG3622	Belongs to the hyi family
IBG28_RS11670	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IBG28_RS11675	COG2610	gluconate transmembrane transporter activity
IBG28_RS11685	COG2081	HI0933 family
IBG28_RS11705	COG3487	Iron-regulated protein
IBG28_RS11715	COG2200	EAL domain
IBG28_RS11715	COG2202	Pas domain
IBG28_RS11715	COG2199	diguanylate cyclase activity
IBG28_RS11800	COG0776	regulation of translation
IBG28_RS11805	COG0072	phenylalanine-tRNA ligase activity
IBG28_RS11810	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IBG28_RS11815	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IBG28_RS11820	COG0291	Belongs to the bacterial ribosomal protein bL35 family
IBG28_RS11825	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IBG28_RS11830	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IBG28_RS11845	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
IBG28_RS11860	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IBG28_RS11865	COG0745	RESPONSE REGULATOR receiver
IBG28_RS11875	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IBG28_RS11880	COG0653	protein targeting
IBG28_RS11885	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
IBG28_RS11900	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IBG28_RS11905	COG1181	Belongs to the D-alanine--D-alanine ligase family
IBG28_RS11910	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IBG28_RS11915	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IBG28_RS11920	COG0772	Belongs to the SEDS family
IBG28_RS11930	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IBG28_RS11935	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IBG28_RS11950	COG3116	cell division
IBG28_RS11955	COG0275	rRNA processing
IBG28_RS11960	COG2001	Belongs to the MraZ family
IBG28_RS11975	COG0745	RESPONSE REGULATOR receiver
IBG28_RS11980	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IBG28_RS11985	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
IBG28_RS11995	COG0330	HflC and HflK could
IBG28_RS12000	COG0330	HflC and HflK could
IBG28_RS12005	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IBG28_RS12010	COG1923	regulation of RNA biosynthetic process
IBG28_RS12015	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IBG28_RS12020	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IBG28_RS12025	COG0860	N-Acetylmuramoyl-L-alanine amidase
IBG28_RS12030	COG0802	atpase or kinase
IBG28_RS12045	COG1162	GTPase activity
IBG28_RS12050	COG1360	Flagellar Motor Protein
IBG28_RS12055	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
IBG28_RS12065	COG0688	phosphatidylethanolamine metabolic process
IBG28_RS12075	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IBG28_RS12085	COG1862	Preprotein translocase
IBG28_RS12090	COG0343	queuine tRNA-ribosyltransferase activity
IBG28_RS12095	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IBG28_RS12115	COG1115	amino acid carrier protein
IBG28_RS12125	COG0252	asparaginase activity
IBG28_RS12140	COG1942	4-Oxalocrotonate Tautomerase
IBG28_RS12160	COG2205	protein histidine kinase activity
IBG28_RS12160	COG2770	Histidine kinase
IBG28_RS12170	COG0463	Glycosyl transferase, family 2
IBG28_RS12210	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IBG28_RS12225	COG0410	ABC transporter
IBG28_RS12230	COG1137	ATPase activity
IBG28_RS12240	COG4977	sequence-specific DNA binding
IBG28_RS12260	COG0583	DNA-binding transcription factor activity
IBG28_RS12305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IBG28_RS12415	COG2026	Addiction module toxin, RelE StbE family
IBG28_RS12420	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IBG28_RS12435	COG0590	tRNA wobble adenosine to inosine editing
IBG28_RS12460	COG2186	Transcriptional regulator
IBG28_RS12465	COG4948	Mandelate Racemase Muconate Lactonizing
IBG28_RS12470	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IBG28_RS12475	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
IBG28_RS12480	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IBG28_RS12495	COG3842	ATPase activity
IBG28_RS12500	COG1175	transmembrane transport
IBG28_RS12505	COG0395	ABC-type sugar transport system, permease component
IBG28_RS12525	COG0840	transmembrane signaling receptor activity
IBG28_RS12540	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
IBG28_RS12545	COG0247	lactate metabolic process
IBG28_RS12545	COG2181	nitrate reductase activity
IBG28_RS12550	COG1902	pentaerythritol trinitrate reductase activity
IBG28_RS12550	COG0446	pyridine nucleotide-disulphide oxidoreductase
IBG28_RS12580	COG0668	transmembrane transport
IBG28_RS12610	COG0454	-acetyltransferase
IBG28_RS12625	COG0454	-acetyltransferase
IBG28_RS12645	COG4372	Transposase
IBG28_RS12670	COG3769	mannosylglycerate metabolic process
IBG28_RS12675	COG1215	transferase activity, transferring glycosyl groups
IBG28_RS12695	COG1132	(ABC) transporter
IBG28_RS12705	COG3290	protein histidine kinase activity
IBG28_RS12725	COG2814	Major facilitator Superfamily
IBG28_RS12745	COG4191	Histidine kinase
IBG28_RS12745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IBG28_RS12750	COG2204	response regulator
IBG28_RS12755	COG0561	phosphatase activity
IBG28_RS12785	COG0288	reversible hydration of carbon dioxide
IBG28_RS12790	COG2226	methyltransferase
IBG28_RS12820	COG4221	oxidoreductase activity
IBG28_RS12890	COG0116	Belongs to the methyltransferase superfamily
IBG28_RS12890	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
IBG28_RS12895	COG0167	dihydroorotate dehydrogenase activity
IBG28_RS12905	COG0714	Associated with various cellular activities
IBG28_RS12935	COG2837	iron assimilation
IBG28_RS12940	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IBG28_RS12955	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
IBG28_RS12960	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IBG28_RS12965	COG0740	serine-type endopeptidase activity
IBG28_RS12970	COG0544	peptidyl-prolyl cis-trans isomerase activity
IBG28_RS12980	COG1295	ribonuclease BN
IBG28_RS12985	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
IBG28_RS12990	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IBG28_RS13000	COG1477	protein flavinylation
IBG28_RS13005	COG2871	sodium ion transport
IBG28_RS13010	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
IBG28_RS13025	COG1805	sodium ion transport
IBG28_RS13030	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
IBG28_RS13035	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IBG28_RS13040	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IBG28_RS13050	COG0616	signal peptide processing
IBG28_RS13055	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IBG28_RS13060	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IBG28_RS13065	COG0328	RNA-DNA hybrid ribonuclease activity
IBG28_RS13075	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IBG28_RS13085	COG3123	guanosine phosphorylase activity
IBG28_RS13090	COG0583	DNA-binding transcription factor activity
IBG28_RS13095	COG0513	Belongs to the DEAD box helicase family
IBG28_RS13110	COG0859	PFAM glycosyl transferase family 9
IBG28_RS13115	COG3642	lipopolysaccharide core region biosynthetic process
IBG28_RS13120	COG1560	Kdo2-lipid A biosynthetic process
IBG28_RS13125	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IBG28_RS13145	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IBG28_RS13150	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
IBG28_RS13155	COG4166	transmembrane transport
IBG28_RS13160	COG0601	transmembrane transport
IBG28_RS13165	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IBG28_RS13170	COG0444	Belongs to the ABC transporter superfamily
IBG28_RS13175	COG4608	Belongs to the ABC transporter superfamily
IBG28_RS13190	COG0513	Belongs to the DEAD box helicase family
IBG28_RS13200	COG0402	S-adenosylhomocysteine deaminase activity
IBG28_RS13205	COG2944	sequence-specific DNA binding
IBG28_RS13265	COG2814	Major facilitator Superfamily
IBG28_RS13270	COG3093	addiction module antidote protein HigA
IBG28_RS13300	COG4804	nuclease activity
IBG28_RS13305	COG0133	tryptophan synthase activity
IBG28_RS13310	COG0159	tryptophan synthase activity
IBG28_RS13320	COG0024	Methionine aminopeptidase
IBG28_RS13335	COG0529	Catalyzes the synthesis of activated sulfate
IBG28_RS13350	COG0457	Tetratricopeptide repeat
IBG28_RS13365	COG0745	RESPONSE REGULATOR receiver
IBG28_RS13370	COG2205	protein histidine kinase activity
IBG28_RS13375	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
IBG28_RS13385	COG1278	Cold shock
IBG28_RS13390	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IBG28_RS13395	COG2971	BadF BadG BcrA BcrD
IBG28_RS13400	COG0363	glucosamine-6-phosphate deaminase activity
IBG28_RS13410	COG1175	transmembrane transport
IBG28_RS13415	COG0395	ABC-type sugar transport system, permease component
IBG28_RS13420	COG3842	ATPase activity
IBG28_RS13425	COG2188	Transcriptional regulator
IBG28_RS13435	COG5002	protein histidine kinase activity
IBG28_RS13435	COG0784	Response regulator, receiver
IBG28_RS13445	COG5433	transposase activity
IBG28_RS13465	COG3040	lipid binding
IBG28_RS13475	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IBG28_RS13480	COG4139	cobalamin transport
IBG28_RS13485	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
IBG28_RS13495	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IBG28_RS13495	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IBG28_RS13500	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IBG28_RS13510	COG2211	Major facilitator Superfamily
IBG28_RS13520	COG0738	Major facilitator superfamily
IBG28_RS13525	COG2217	Heavy metal translocating P-type atpase
IBG28_RS13550	COG3842	ATPase activity
IBG28_RS13560	COG0483	inositol monophosphate 1-phosphatase activity
IBG28_RS13570	COG1609	Transcriptional regulator
IBG28_RS13575	COG0824	Thioesterase
IBG28_RS13580	COG0673	inositol 2-dehydrogenase activity
IBG28_RS13585	COG3718	enzyme involved in inositol metabolism
IBG28_RS13605	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IBG28_RS13610	COG0673	inositol 2-dehydrogenase activity
IBG28_RS13620	COG1172	Belongs to the binding-protein-dependent transport system permease family
IBG28_RS13650	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
IBG28_RS13655	COG0402	S-adenosylhomocysteine deaminase activity
IBG28_RS13665	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IBG28_RS13670	COG0183	Belongs to the thiolase family
IBG28_RS13675	COG1250	3-hydroxyacyl-CoA dehydrogenase
IBG28_RS13675	COG1024	Enoyl-CoA hydratase
IBG28_RS13690	COG1024	Enoyl-CoA hydratase
IBG28_RS13700	COG0318	PFAM AMP-dependent synthetase and ligase
IBG28_RS13710	COG1960	acyl-CoA dehydrogenase activity
IBG28_RS13715	COG0523	cobalamin synthesis protein
IBG28_RS13735	COG2252	PERMEase
IBG28_RS13750	COG2205	protein histidine kinase activity
IBG28_RS13755	COG0745	RESPONSE REGULATOR receiver
IBG28_RS13760	COG3678	ATP-independent chaperone mediated protein folding
IBG28_RS13775	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IBG28_RS13790	COG2979	Protein of unknown function (DUF533)
IBG28_RS13830	COG0717	Belongs to the dCTP deaminase family
IBG28_RS13835	COG0489	protein tyrosine kinase activity
IBG28_RS13840	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IBG28_RS13840	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IBG28_RS13845	COG4657	Part of a membrane complex involved in electron transport
IBG28_RS13850	COG2878	Part of a membrane complex involved in electron transport
IBG28_RS13855	COG4656	Part of a membrane complex involved in electron transport
IBG28_RS13860	COG4658	electron transport chain
IBG28_RS13865	COG4659	FMN binding
IBG28_RS13870	COG4660	Part of a membrane complex involved in electron transport
IBG28_RS13875	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IBG28_RS13890	COG0724	RNA recognition motif
IBG28_RS13900	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IBG28_RS13905	COG0137	argininosuccinate synthase activity
IBG28_RS13915	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IBG28_RS13920	COG2832	Protein of unknown function (DUF454)
IBG28_RS13940	COG0826	peptidase U32
IBG28_RS13945	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IBG28_RS13955	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
IBG28_RS13995	COG4115	mRNA cleavage
IBG28_RS14000	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IBG28_RS14005	COG4988	ABC transporter
IBG28_RS14010	COG4890	Cyd operon protein YbgT
IBG28_RS14015	COG1294	oxidase, subunit
IBG28_RS14060	COG2957	Belongs to the agmatine deiminase family
IBG28_RS14065	COG1162	GTPase activity
IBG28_RS14070	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
IBG28_RS14085	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IBG28_RS14095	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
IBG28_RS14115	COG1238	metal cluster binding
IBG28_RS14130	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IBG28_RS14140	COG0840	transmembrane signaling receptor activity
IBG28_RS14165	COG0514	ATP-dependent DNA helicase (RecQ)
IBG28_RS14185	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IBG28_RS14190	COG0322	excinuclease ABC activity
IBG28_RS14195	COG2197	response regulator
IBG28_RS14220	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
IBG28_RS14235	COG2920	part of a sulfur-relay system
IBG28_RS14240	COG1648	precorrin-2 dehydrogenase activity
IBG28_RS14240	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IBG28_RS14245	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IBG28_RS14250	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IBG28_RS14255	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IBG28_RS14260	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
IBG28_RS14265	COG1674	ftsk spoiiie
IBG28_RS14275	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
IBG28_RS14280	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IBG28_RS14285	COG0542	response to heat
IBG28_RS14290	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
IBG28_RS14295	COG1278	Cold shock
IBG28_RS14310	COG0482	sulfurtransferase activity
IBG28_RS14315	COG2915	High frequency lysogenization protein hflD homolog
IBG28_RS14330	COG2850	peptidyl-arginine hydroxylation
IBG28_RS14340	COG0545	Peptidyl-prolyl cis-trans isomerase
IBG28_RS14360	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IBG28_RS14365	COG1280	lysine exporter protein (LysE YggA)
IBG28_RS14380	COG0306	phosphate transporter
IBG28_RS14385	COG1760	l-serine dehydratase
IBG28_RS14425	COG1028	Short-chain dehydrogenase reductase Sdr
IBG28_RS14440	COG0671	phosphoesterase, PA-phosphatase related
IBG28_RS14455	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IBG28_RS14480	COG0488	(ABC) transporter
IBG28_RS14510	COG1253	flavin adenine dinucleotide binding
IBG28_RS14545	COG0840	transmembrane signaling receptor activity
IBG28_RS14550	COG2202	Pas domain
IBG28_RS14550	COG2200	EAL domain
IBG28_RS14550	COG2199	diguanylate cyclase activity
IBG28_RS14560	COG1272	protein, Hemolysin III
IBG28_RS14570	COG1968	undecaprenyl-diphosphatase activity
IBG28_RS14580	COG1840	ABC-type Fe3 transport system, periplasmic component
IBG28_RS14585	COG3842	ATPase activity
IBG28_RS14610	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IBG28_RS14620	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
IBG28_RS14640	COG3248	Nucleoside-binding outer membrane protein
IBG28_RS14645	COG1454	alcohol dehydrogenase
IBG28_RS14650	COG1944	ATP diphosphatase activity
IBG28_RS14700	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
IBG28_RS14705	COG1797	cobyrinic acid a,c-diamide synthase activity
IBG28_RS14715	COG5002	protein histidine kinase activity
IBG28_RS14715	COG0784	Response regulator, receiver
IBG28_RS14720	COG5001	Diguanylate cyclase
IBG28_RS14720	COG5002	protein histidine kinase activity
IBG28_RS14730	COG0583	DNA-binding transcription factor activity
IBG28_RS14740	COG0346	lactoylglutathione lyase activity
IBG28_RS14745	COG0450	alkyl hydroperoxide reductase
IBG28_RS14750	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IBG28_RS14755	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IBG28_RS14760	COG0583	DNA-binding transcription factor activity
IBG28_RS14765	COG2205	protein histidine kinase activity
IBG28_RS14770	COG0745	RESPONSE REGULATOR receiver
IBG28_RS14785	COG0009	L-threonylcarbamoyladenylate synthase
IBG28_RS14790	COG0613	PHP domain protein
IBG28_RS14795	COG2917	probably involved in intracellular septation
IBG28_RS14800	COG2350	Protein conserved in bacteria
IBG28_RS14810	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IBG28_RS14815	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
IBG28_RS14815	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IBG28_RS14830	COG3089	Belongs to the UPF0270 family
IBG28_RS14835	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IBG28_RS14840	COG3115	cell septum assembly
IBG28_RS14845	COG4235	cytochrome complex assembly
IBG28_RS14855	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IBG28_RS14860	COG1138	Cytochrome C-type biogenesis protein
IBG28_RS14865	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
IBG28_RS14880	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IBG28_RS14885	COG4133	protoheme IX ABC transporter activity
IBG28_RS14905	COG0835	chemotaxis
IBG28_RS14915	COG1192	Involved in chromosome partitioning
IBG28_RS14925	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
IBG28_RS14935	COG2198	Histidine kinase
IBG28_RS14935	COG0784	Response regulator, receiver
IBG28_RS14935	COG0643	Histidine kinase
IBG28_RS14940	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
IBG28_RS14970	COG1684	flagellar biosynthetic protein fliR
IBG28_RS14975	COG1987	bacterial-type flagellum assembly
IBG28_RS14985	COG3190	flagellar
IBG28_RS15010	COG3437	response regulator, receiver
IBG28_RS15055	COG1677	Flagellar hook-basal body complex protein FliE
IBG28_RS15075	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
IBG28_RS15080	COG2226	methyltransferase
IBG28_RS15085	COG2267	carboxylic ester hydrolase activity
IBG28_RS15090	COG0156	8-amino-7-oxononanoate synthase activity
IBG28_RS15095	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
IBG28_RS15100	COG1040	competence protein
IBG28_RS15110	COG0840	transmembrane signaling receptor activity
IBG28_RS15115	COG0305	Participates in initiation and elongation during chromosome replication
IBG28_RS15120	COG0359	binds to the 23S rRNA
IBG28_RS15130	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IBG28_RS15135	COG0360	Binds together with S18 to 16S ribosomal RNA
IBG28_RS15160	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
IBG28_RS15165	COG1178	ABC-type Fe3 transport system permease component
IBG28_RS15170	COG4143	(ABC) transporter
IBG28_RS15175	COG1519	Transferase
IBG28_RS15180	COG1132	(ABC) transporter
IBG28_RS15185	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
IBG28_RS15185	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
IBG28_RS15190	COG2942	2-epimerase
IBG28_RS15195	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IBG28_RS15200	COG0859	PFAM glycosyl transferase family 9
IBG28_RS15205	COG0463	Glycosyl transferase, family 2
IBG28_RS15215	COG0859	PFAM glycosyl transferase family 9
IBG28_RS15230	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
IBG28_RS15240	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
IBG28_RS15245	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IBG28_RS15250	COG1280	lysine exporter protein (LysE YggA)
IBG28_RS15265	COG0435	Glutathione S-transferase
IBG28_RS15270	COG2992	FlgJ-related protein
IBG28_RS15280	COG0583	DNA-binding transcription factor activity
IBG28_RS15300	COG1091	dTDP-4-dehydrorhamnose reductase activity
IBG28_RS15305	COG0084	hydrolase, TatD family'
IBG28_RS15310	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
IBG28_RS15315	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IBG28_RS15325	COG0483	inositol monophosphate 1-phosphatase activity
IBG28_RS15335	COG3132	Protein of unknown function, DUF480
IBG28_RS15345	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
IBG28_RS15365	COG0517	IMP dehydrogenase activity
IBG28_RS15365	COG4175	Glycine betaine
IBG28_RS15375	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IBG28_RS15380	COG0519	Catalyzes the synthesis of GMP from XMP
IBG28_RS15380	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IBG28_RS15385	COG1177	transmembrane transport
IBG28_RS15390	COG1176	ABC-type spermidine putrescine transport system, permease component I
IBG28_RS15395	COG3842	ATPase activity
IBG28_RS15405	COG0174	glutamine synthetase
IBG28_RS15410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IBG28_RS15415	COG1012	belongs to the aldehyde dehydrogenase family
IBG28_RS15425	COG1279	arginine transmembrane transporter activity
IBG28_RS15430	COG0583	DNA-binding transcription factor activity
IBG28_RS15440	COG1172	Belongs to the binding-protein-dependent transport system permease family
IBG28_RS15445	COG1172	Belongs to the binding-protein-dependent transport system permease family
IBG28_RS15450	COG1129	ABC transporter
IBG28_RS15455	COG1879	ABC-type sugar transport system periplasmic component
IBG28_RS15465	COG0583	DNA-binding transcription factor activity
IBG28_RS15470	COG1741	Belongs to the pirin family
IBG28_RS15485	COG1724	mRNA binding
IBG28_RS15490	COG1598	PFAM Uncharacterised protein family UPF0150
IBG28_RS15530	COG1203	CRISPR-associated helicase, Cas3
IBG28_RS15560	COG1448	Aminotransferase
IBG28_RS15565	COG3318	Belongs to the UPF0149 family
IBG28_RS15565	COG3012	SEC-C Motif Domain Protein
IBG28_RS15585	COG3150	esterase
IBG28_RS15600	COG0494	nUDIX hydrolase
IBG28_RS15605	COG0519	Catalyzes the synthesis of GMP from XMP
IBG28_RS15610	COG1086	Polysaccharide biosynthesis protein
IBG28_RS15615	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IBG28_RS15620	COG1083	cytidylyl-transferase
IBG28_RS15630	COG2089	acid synthase
IBG28_RS15660	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IBG28_RS15670	COG2770	Histidine kinase
IBG28_RS15670	COG3437	response regulator, receiver
IBG28_RS15690	COG1706	bacterial-type flagellum-dependent cell motility
IBG28_RS15695	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
IBG28_RS15700	COG4786	Flagellar basal body rod
IBG28_RS15705	COG4787	bacterial-type flagellum-dependent cell motility
IBG28_RS15720	COG1558	bacterial-type flagellum-dependent cell motility
IBG28_RS15725	COG1815	bacterial-type flagellum-dependent cell motility
IBG28_RS15730	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
IBG28_RS15735	COG0784	Response regulator, receiver
IBG28_RS15735	COG0835	chemotaxis
IBG28_RS15760	COG1765	OsmC-like protein
IBG28_RS15765	COG0134	indole-3-glycerol-phosphate synthase activity
IBG28_RS15770	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IBG28_RS15780	COG2239	Acts as a magnesium transporter
IBG28_RS15785	COG0668	transmembrane transport
IBG28_RS15790	COG0546	phosphoglycolate phosphatase activity
IBG28_RS15795	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IBG28_RS15805	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
IBG28_RS15810	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
IBG28_RS15815	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IBG28_RS15820	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
IBG28_RS15825	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IBG28_RS15830	COG2967	ApaG domain
IBG28_RS15835	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IBG28_RS15845	COG0617	tRNA 3'-terminal CCA addition
IBG28_RS15855	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IBG28_RS15860	COG0828	Belongs to the bacterial ribosomal protein bS21 family
IBG28_RS15870	COG0358	DNA primase activity
IBG28_RS15880	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
IBG28_RS15885	COG0800	Aldolase
IBG28_RS15890	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IBG28_RS15895	COG0837	glucose binding
IBG28_RS15915	COG1607	acyl-coa hydrolase
IBG28_RS15925	COG1185	polyribonucleotide nucleotidyltransferase activity
IBG28_RS15930	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IBG28_RS15935	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IBG28_RS15940	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IBG28_RS15945	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IBG28_RS15950	COG0195	Participates in both transcription termination and antitermination
IBG28_RS15955	COG0779	Required for maturation of 30S ribosomal subunits
IBG28_RS15965	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IBG28_RS15970	COG0149	triose-phosphate isomerase activity
IBG28_RS15975	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IBG28_RS15980	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IBG28_RS15985	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IBG28_RS15990	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
IBG28_RS16005	COG0316	Belongs to the HesB IscA family
IBG28_RS16010	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IBG28_RS16020	COG5002	protein histidine kinase activity
IBG28_RS16025	COG0745	RESPONSE REGULATOR receiver
IBG28_RS16030	COG5002	protein histidine kinase activity
IBG28_RS16035	COG0596	Alpha beta hydrolase
IBG28_RS16050	COG4191	Histidine kinase
IBG28_RS16065	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
IBG28_RS16070	COG3639	organic phosphonate transmembrane transporter activity
IBG28_RS16080	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IBG28_RS16110	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IBG28_RS16115	COG2308	Evidence 4 Homologs of previously reported genes of
IBG28_RS16130	COG2307	Protein conserved in bacteria
IBG28_RS16130	COG2308	Evidence 4 Homologs of previously reported genes of
IBG28_RS16140	COG0513	Belongs to the DEAD box helicase family
IBG28_RS16145	COG1823	symporter activity
IBG28_RS16150	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
IBG28_RS16165	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
IBG28_RS16170	COG3177	Filamentation induced by cAMP protein fic
IBG28_RS16190	COG4584	PFAM Integrase catalytic
IBG28_RS16195	COG1484	DNA-dependent DNA replication
IBG28_RS16235	COG1335	isochorismatase
IBG28_RS16250	COG2188	Transcriptional regulator
IBG28_RS16265	COG0840	transmembrane signaling receptor activity
IBG28_RS16275	COG0745	RESPONSE REGULATOR receiver
IBG28_RS16280	COG2205	protein histidine kinase activity
IBG28_RS16280	COG0784	Response regulator, receiver
IBG28_RS16290	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
IBG28_RS16295	COG0830	nickel cation binding
IBG28_RS16300	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
IBG28_RS16305	COG0804	urea catabolic process
IBG28_RS16310	COG0832	Belongs to the urease beta subunit family
IBG28_RS16315	COG0831	urea catabolic process
IBG28_RS16320	COG0829	nickel cation binding
IBG28_RS16365	COG2431	L-lysine efflux transmembrane transporter activity
IBG28_RS16400	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IBG28_RS16410	COG0463	Glycosyl transferase, family 2
IBG28_RS16430	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IBG28_RS16435	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IBG28_RS16485	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IBG28_RS16500	COG0438	transferase activity, transferring glycosyl groups
IBG28_RS16520	COG1215	transferase activity, transferring glycosyl groups
IBG28_RS16560	COG0543	2 iron, 2 sulfur cluster binding
IBG28_RS16560	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IBG28_RS16580	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IBG28_RS16590	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IBG28_RS16610	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
IBG28_RS16635	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
IBG28_RS16640	COG1943	Transposase
IBG28_RS16695	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IBG28_RS16705	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IBG28_RS16740	COG3706	GGDEF domain
IBG28_RS16745	COG4628	conserved protein (DUF2132)
IBG28_RS16750	COG0673	inositol 2-dehydrogenase activity
IBG28_RS16760	COG0673	inositol 2-dehydrogenase activity
IBG28_RS16770	COG3842	ATPase activity
IBG28_RS16775	COG3833	ABC-type maltose transport systems, permease component
IBG28_RS16780	COG1175	transmembrane transport
IBG28_RS16785	COG1653	transport
IBG28_RS16790	COG1609	Transcriptional regulator
IBG28_RS16805	COG0300	oxidoreductase activity
IBG28_RS16830	COG1902	pentaerythritol trinitrate reductase activity
IBG28_RS16840	COG0300	oxidoreductase activity
IBG28_RS16855	COG0604	alcohol dehydrogenase
IBG28_RS16870	COG1129	ABC transporter
IBG28_RS16870	COG0842	Transport permease protein
IBG28_RS16880	COG3829	transcription factor binding
IBG28_RS16890	COG0446	pyridine nucleotide-disulphide oxidoreductase
IBG28_RS16910	COG1473	amidohydrolase
IBG28_RS16920	COG3344	reverse transcriptase
IBG28_RS16930	COG0165	Argininosuccinate lyase
IBG28_RS16955	COG0840	transmembrane signaling receptor activity
IBG28_RS16970	COG3022	response to hydroperoxide
IBG28_RS16975	COG2890	protein-(glutamine-N5) methyltransferase activity
IBG28_RS16980	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IBG28_RS16985	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
IBG28_RS16995	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
IBG28_RS17000	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IBG28_RS17005	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IBG28_RS17010	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
IBG28_RS17015	COG0193	aminoacyl-tRNA hydrolase activity
IBG28_RS17060	COG1496	oxidoreductase activity
IBG28_RS17080	COG1278	Cold shock
IBG28_RS17085	COG0004	ammonium transporteR
IBG28_RS17110	COG3122	Protein conserved in bacteria
IBG28_RS17115	COG1278	Cold shock
IBG28_RS17145	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
IBG28_RS17150	COG0511	ligase activity, forming carbon-carbon bonds
IBG28_RS17150	COG5016	pyruvate
IBG28_RS17185	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
IBG28_RS17190	COG0527	aspartate kinase activity
IBG28_RS17195	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IBG28_RS17200	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IBG28_RS17205	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IBG28_RS17240	COG3039	Transposase
IBG28_RS17265	COG2132	Multicopper oxidase
IBG28_RS17285	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IBG28_RS17330	COG1484	DNA-dependent DNA replication
IBG28_RS17335	COG4584	PFAM Integrase catalytic
IBG28_RS17370	COG0789	Transcriptional regulator
IBG28_RS17395	COG3039	Transposase
IBG28_RS17425	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IBG28_RS17435	COG1058	Belongs to the CinA family
IBG28_RS17435	COG1546	Belongs to the CinA family
IBG28_RS17440	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IBG28_RS17445	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
IBG28_RS17450	COG2199	diguanylate cyclase activity
IBG28_RS17450	COG2200	EAL domain
IBG28_RS17450	COG2202	Pas domain
IBG28_RS17455	COG0129	dihydroxy-acid dehydratase activity
IBG28_RS17460	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
IBG28_RS17490	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IBG28_RS17510	COG3657	addiction module killer protein
IBG28_RS17515	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IBG28_RS17525	COG0494	nUDIX hydrolase
IBG28_RS17535	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
IBG28_RS17545	COG3842	ATPase activity
IBG28_RS17550	COG1178	ABC-type Fe3 transport system permease component
IBG28_RS17555	COG1840	ABC-type Fe3 transport system, periplasmic component
IBG28_RS17560	COG1639	'signal transduction protein
IBG28_RS17565	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IBG28_RS17570	COG0006	proline dipeptidase activity
IBG28_RS17575	COG3079	Belongs to the UPF0149 family
IBG28_RS17580	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IBG28_RS17595	COG2199	diguanylate cyclase activity
IBG28_RS17615	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IBG28_RS17620	COG0335	large ribosomal subunit rRNA binding
IBG28_RS17625	COG0336	Belongs to the RNA methyltransferase TrmD family
IBG28_RS17630	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IBG28_RS17635	COG0228	four-way junction DNA binding
IBG28_RS17640	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IBG28_RS17650	COG4536	flavin adenine dinucleotide binding
IBG28_RS17660	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IBG28_RS17675	COG0668	transmembrane transport
IBG28_RS17690	COG0483	inositol monophosphate 1-phosphatase activity
IBG28_RS17700	COG0572	uridine kinase
IBG28_RS17705	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IBG28_RS17785	COG0726	polysaccharide deacetylase
IBG28_RS17785	COG1649	PFAM Uncharacterised BCR, COG1649
IBG28_RS17790	COG0156	8-amino-7-oxononanoate synthase activity
IBG28_RS17795	COG1063	alcohol dehydrogenase
IBG28_RS17810	COG2066	Belongs to the glutaminase family
IBG28_RS17815	COG1611	Belongs to the LOG family
IBG28_RS17820	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IBG28_RS17825	COG0612	Peptidase, M16
IBG28_RS17830	COG4771	TonB-dependent receptor
IBG28_RS17840	COG1595	DNA-templated transcription, initiation
IBG28_RS17855	COG0583	DNA-binding transcription factor activity
IBG28_RS17860	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IBG28_RS17865	COG2183	response to ionizing radiation
IBG28_RS17875	COG0220	tRNA (guanine-N7-)-methyltransferase activity
IBG28_RS17895	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
IBG28_RS17905	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
IBG28_RS17915	COG1194	a g-specific adenine glycosylase
IBG28_RS17925	COG0131	Imidazoleglycerol-phosphate dehydratase
IBG28_RS17930	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IBG28_RS17935	COG0107	imidazoleglycerol-phosphate synthase activity
IBG28_RS17950	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
IBG28_RS17965	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
IBG28_RS17970	COG1492	cobalamin metabolic process
IBG28_RS18005	COG0579	oxidoreductase
IBG28_RS18010	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
IBG28_RS18010	COG0517	IMP dehydrogenase activity
IBG28_RS18015	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IBG28_RS18020	COG0488	(ABC) transporter
IBG28_RS18055	COG0590	tRNA wobble adenosine to inosine editing
IBG28_RS18070	COG0525	valine-tRNA ligase activity
IBG28_RS18085	COG0795	lipopolysaccharide-transporting ATPase activity
IBG28_RS18090	COG0795	lipopolysaccharide-transporting ATPase activity
IBG28_RS18095	COG0436	Aminotransferase
IBG28_RS18110	COG2204	response regulator
IBG28_RS18115	COG0617	tRNA 3'-terminal CCA addition
IBG28_RS18120	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IBG28_RS18125	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
IBG28_RS18130	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
IBG28_RS18135	COG0166	Belongs to the GPI family
IBG28_RS18140	COG4115	mRNA cleavage
IBG28_RS18145	COG2161	toxin-antitoxin pair type II binding
IBG28_RS18155	COG3177	Filamentation induced by cAMP protein fic
IBG28_RS18180	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IBG28_RS18180	COG2111	Na H antiporter
IBG28_RS18185	COG1006	Multisubunit Na H antiporter MnhC subunit
IBG28_RS18190	COG0651	ATP synthesis coupled electron transport
IBG28_RS18195	COG1863	multisubunit Na H antiporter MnhE subunit
IBG28_RS18200	COG2212	antiporter activity
IBG28_RS18205	COG1320	monovalent cation:proton antiporter activity
IBG28_RS18225	COG2211	Major facilitator Superfamily
IBG28_RS18230	COG2814	Major facilitator Superfamily
IBG28_RS18235	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IBG28_RS18240	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
IBG28_RS18280	COG0840	transmembrane signaling receptor activity
IBG28_RS18285	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
IBG28_RS18285	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
IBG28_RS18295	COG2072	flavoprotein involved in K transport
IBG28_RS18305	COG2144	transferase activity, transferring acyl groups
IBG28_RS18335	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IBG28_RS18345	COG1294	oxidase, subunit
IBG28_RS18350	COG1271	oxidase subunit
IBG28_RS18355	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IBG28_RS18365	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IBG28_RS18385	COG0210	DNA helicase
IBG28_RS18425	COG0606	chelatase, subunit chli
IBG28_RS18440	COG0347	Belongs to the P(II) protein family
IBG28_RS18445	COG0004	ammonium transporteR
IBG28_RS18450	COG3153	acetyltransferase
IBG28_RS18450	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IBG28_RS18460	COG3313	Fe-S protein
IBG28_RS18485	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IBG28_RS18490	COG0583	DNA-binding transcription factor activity
IBG28_RS18510	COG1012	belongs to the aldehyde dehydrogenase family
IBG28_RS18515	COG3724	N-succinylarginine dihydrolase activity
IBG28_RS18520	COG2918	glutathione biosynthetic process
IBG28_RS18525	COG0218	Necessary for normal cell division and for the maintenance of normal septation
IBG28_RS18530	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IBG28_RS18540	COG2226	methyltransferase
IBG28_RS18545	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IBG28_RS18550	COG0140	phosphoribosyl-ATP diphosphatase activity
IBG28_RS18555	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IBG28_RS18560	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IBG28_RS18570	COG2423	ornithine cyclodeaminase activity
IBG28_RS18575	COG1490	D-aminoacyl-tRNA deacylase activity
IBG28_RS18580	COG1217	gtp-binding protein TYPA
IBG28_RS18585	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IBG28_RS18585	COG0301	tRNA thio-modification
IBG28_RS18610	COG0009	L-threonylcarbamoyladenylate synthase
IBG28_RS18640	COG2861	carbohydrate metabolic process
IBG28_RS18645	COG0793	Belongs to the peptidase S41A family
IBG28_RS18650	COG4942	peptidase
IBG28_RS18655	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IBG28_RS18660	COG0583	DNA-binding transcription factor activity
IBG28_RS18670	COG1012	belongs to the aldehyde dehydrogenase family
IBG28_RS18675	COG0583	DNA-binding transcription factor activity
IBG28_RS18685	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IBG28_RS18695	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
IBG28_RS18715	COG0653	protein targeting
IBG28_RS18725	COG0662	Cupin 2, conserved barrel domain protein
IBG28_RS18725	COG2207	Transcriptional regulator
IBG28_RS18735	COG4251	negative regulation of phosphorylation
IBG28_RS18735	COG5001	Diguanylate cyclase
IBG28_RS18735	COG3706	GGDEF domain
IBG28_RS18735	COG2203	Gaf domain
IBG28_RS18745	COG2176	DNA-directed DNA polymerase activity
IBG28_RS18750	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
IBG28_RS18775	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IBG28_RS18790	COG3265	gluconokinase activity
IBG28_RS18795	COG1609	Transcriptional regulator
IBG28_RS18800	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
IBG28_RS18805	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IBG28_RS18810	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IBG28_RS18815	COG1120	ATPase activity
IBG28_RS18835	COG0583	DNA-binding transcription factor activity
IBG28_RS18885	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
IBG28_RS18895	COG0456	acetyltransferase
IBG28_RS18900	COG1434	Gram-negative-bacterium-type cell wall biogenesis
IBG28_RS18910	COG0095	Lipoate-protein ligase
IBG28_RS18925	COG0505	Belongs to the CarA family
IBG28_RS18930	COG0693	protein deglycase activity
IBG28_RS18935	COG0456	acetyltransferase
IBG28_RS18950	COG0765	amino acid transport
IBG28_RS18965	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
IBG28_RS18970	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IBG28_RS18980	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IBG28_RS18985	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IBG28_RS18985	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IBG28_RS18990	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IBG28_RS19010	COG0488	(ABC) transporter
IBG28_RS19045	COG1522	sequence-specific DNA binding
IBG28_RS19050	COG0840	transmembrane signaling receptor activity
IBG28_RS19065	COG0204	Acyl-transferase
IBG28_RS19070	COG5001	Diguanylate cyclase
IBG28_RS19070	COG3300	MHYT domain
IBG28_RS19075	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IBG28_RS19075	COG1522	sequence-specific DNA binding
IBG28_RS19080	COG2313	pseudouridylate synthase activity
IBG28_RS19085	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
IBG28_RS19090	COG0583	DNA-binding transcription factor activity
IBG28_RS19095	COG0697	spore germination
IBG28_RS19105	COG5001	Diguanylate cyclase
IBG28_RS19125	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IBG28_RS19140	COG4221	oxidoreductase activity
IBG28_RS19150	COG1595	DNA-templated transcription, initiation
IBG28_RS19155	COG3806	Anti-sigma factor
IBG28_RS19185	COG1012	belongs to the aldehyde dehydrogenase family
IBG28_RS19200	COG0737	Belongs to the 5'-nucleotidase family
IBG28_RS19215	COG2738	Putative neutral zinc metallopeptidase
IBG28_RS19220	COG0484	heat shock protein binding
IBG28_RS19225	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
IBG28_RS19240	COG0848	biopolymer transport protein
IBG28_RS19245	COG0811	peptide transport
IBG28_RS19250	COG0598	Magnesium transport protein CorA
IBG28_RS19270	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
IBG28_RS19280	COG0732	type I restriction modification DNA specificity domain
IBG28_RS19305	COG2207	Transcriptional regulator
IBG28_RS19310	COG0534	Mate efflux family protein
IBG28_RS19315	COG2814	Major facilitator Superfamily
IBG28_RS19340	COG3344	reverse transcriptase
IBG28_RS19355	COG0129	dihydroxy-acid dehydratase activity
IBG28_RS19370	COG4214	carbohydrate transport
IBG28_RS19380	COG4213	ABC transporter substrate-binding protein
IBG28_RS19385	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IBG28_RS19385	COG4651	solute:proton antiporter activity
IBG28_RS19390	COG3344	reverse transcriptase
IBG28_RS19400	COG3093	addiction module antidote protein HigA
IBG28_RS19415	COG0493	'glutamate synthase
IBG28_RS19420	COG0069	glutamate synthase activity
IBG28_RS19420	COG0067	glutamate synthase
IBG28_RS19420	COG0070	glutamate synthase
IBG28_RS19430	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IBG28_RS19435	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IBG28_RS19465	COG0281	malic enzyme
IBG28_RS19475	COG0254	rRNA binding
IBG28_RS19480	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IBG28_RS19490	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
IBG28_RS19495	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
IBG28_RS19515	COG0252	asparaginase activity
IBG28_RS19520	COG0018	arginyl-trna synthetase
IBG28_RS19525	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IBG28_RS19530	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IBG28_RS19540	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
IBG28_RS19545	COG0655	NAD(P)H dehydrogenase (quinone) activity
IBG28_RS19575	COG1489	DNA binding
IBG28_RS19590	COG1280	lysine exporter protein (LysE YggA)
IBG28_RS19610	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IBG28_RS19610	COG0519	Catalyzes the synthesis of GMP from XMP
IBG28_RS19625	COG0840	transmembrane signaling receptor activity
IBG28_RS19630	COG2204	response regulator
IBG28_RS19640	COG1271	oxidase subunit
IBG28_RS19645	COG1294	oxidase, subunit
IBG28_RS19675	COG0745	RESPONSE REGULATOR receiver
IBG28_RS19680	COG0697	spore germination
IBG28_RS19740	COG1643	Atp-dependent helicase
IBG28_RS19765	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IBG28_RS19770	COG1047	Peptidyl-prolyl cis-trans
IBG28_RS19775	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IBG28_RS19780	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IBG28_RS19785	COG0196	riboflavin kinase activity
IBG28_RS19790	COG0728	peptidoglycan biosynthetic process
IBG28_RS19795	COG0268	Binds directly to 16S ribosomal RNA
IBG28_RS19800	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
IBG28_RS19805	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IBG28_RS19810	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IBG28_RS19815	COG0211	Belongs to the bacterial ribosomal protein bL27 family
IBG28_RS19820	COG0261	This protein binds to 23S rRNA in the presence of protein L20
IBG28_RS19825	COG0142	geranyltranstransferase activity
IBG28_RS19835	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IBG28_RS19870	COG0629	single-stranded DNA binding
IBG28_RS19875	COG2814	Major facilitator Superfamily
IBG28_RS19885	COG0203	ribosomal protein L17
IBG28_RS19890	COG0202	RNA polymerase activity
IBG28_RS19895	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IBG28_RS19900	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IBG28_RS19905	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IBG28_RS19910	COG0257	Belongs to the bacterial ribosomal protein bL36 family
IBG28_RS19920	COG0200	Binds to the 23S rRNA
IBG28_RS19925	COG1841	ribosomal large subunit assembly
IBG28_RS19930	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IBG28_RS19935	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IBG28_RS19940	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IBG28_RS19945	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IBG28_RS19950	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IBG28_RS19955	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IBG28_RS19960	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IBG28_RS19965	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IBG28_RS19970	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IBG28_RS19975	COG0255	Belongs to the universal ribosomal protein uL29 family
IBG28_RS19980	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IBG28_RS19985	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IBG28_RS19990	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IBG28_RS19995	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IBG28_RS20000	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IBG28_RS20005	COG0089	rRNA binding
IBG28_RS20010	COG0088	Forms part of the polypeptide exit tunnel
IBG28_RS20015	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IBG28_RS20020	COG0051	transcription antitermination factor activity, RNA binding
IBG28_RS20025	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IBG28_RS20030	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IBG28_RS20035	COG0049	tRNA binding
IBG28_RS20040	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IBG28_RS20045	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IBG28_RS20050	COG0085	RNA polymerase activity
IBG28_RS20055	COG0222	ribosome binding
IBG28_RS20060	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IBG28_RS20065	COG0081	regulation of translation
IBG28_RS20070	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IBG28_RS20110	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
IBG28_RS20115	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
IBG28_RS20115	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
IBG28_RS20135	COG2723	6-phospho-beta-galactosidase activity
IBG28_RS20140	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
IBG28_RS20170	COG1177	transmembrane transport
IBG28_RS20175	COG1176	ABC-type spermidine putrescine transport system, permease component I
IBG28_RS20180	COG3842	ATPase activity
IBG28_RS20190	COG0840	transmembrane signaling receptor activity
IBG28_RS20195	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IBG28_RS20200	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IBG28_RS20210	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IBG28_RS20235	COG0126	phosphoglycerate kinase activity
IBG28_RS20240	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IBG28_RS20245	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IBG28_RS20250	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IBG28_RS20255	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IBG28_RS20265	COG0189	ligase activity
IBG28_RS20280	COG2177	Part of the ABC transporter FtsEX involved in
IBG28_RS20285	COG2884	Cell division ATP-binding protein ftsE
IBG28_RS20290	COG0552	protein localization to endoplasmic reticulum
IBG28_RS20300	COG0742	ribosomal rna small subunit methyltransferase
IBG28_RS20305	COG0840	transmembrane signaling receptor activity
IBG28_RS20310	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IBG28_RS20315	COG2813	Specifically methylates the guanine in position
IBG28_RS20315	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IBG28_RS20320	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IBG28_RS20325	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IBG28_RS20330	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IBG28_RS20335	COG2119	membrane
IBG28_RS20345	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
IBG28_RS20350	COG1609	Transcriptional regulator
IBG28_RS20355	COG0366	Alpha amylase catalytic
IBG28_RS20360	COG3842	ATPase activity
IBG28_RS20365	COG0395	ABC-type sugar transport system, permease component
IBG28_RS20370	COG1175	transmembrane transport
IBG28_RS20375	COG1653	transport
IBG28_RS20380	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IBG28_RS20390	COG2205	protein histidine kinase activity
IBG28_RS20395	COG1653	transport
IBG28_RS20400	COG1175	transmembrane transport
IBG28_RS20405	COG0395	ABC-type sugar transport system, permease component
IBG28_RS20410	COG3842	ATPase activity
IBG28_RS20415	COG0737	Belongs to the 5'-nucleotidase family
IBG28_RS20425	COG3300	MHYT domain
IBG28_RS20425	COG5001	Diguanylate cyclase
IBG28_RS20435	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IBG28_RS20440	COG1561	YicC-like family, N-terminal region
IBG28_RS20455	COG3550	peptidyl-serine autophosphorylation
IBG28_RS20460	COG3620	sequence-specific DNA binding
IBG28_RS20505	COG2205	protein histidine kinase activity
IBG28_RS20505	COG0784	Response regulator, receiver
IBG28_RS20520	COG3177	Filamentation induced by cAMP protein fic
IBG28_RS20570	COG2807	transmembrane transport
IBG28_RS20580	COG0194	GDP metabolic process
IBG28_RS20585	COG1758	RNA polymerase activity
IBG28_RS20590	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IBG28_RS20605	COG0583	DNA-binding transcription factor activity
IBG28_RS20610	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IBG28_RS20625	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IBG28_RS20630	COG4597	amino acid ABC transporter
IBG28_RS20635	COG0765	amino acid transport
IBG28_RS20640	COG1126	abc transporter atp-binding protein
IBG28_RS20655	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
IBG28_RS20670	COG0745	RESPONSE REGULATOR receiver
IBG28_RS20685	COG0601	transmembrane transport
IBG28_RS20690	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IBG28_RS20720	COG1956	GAF domain-containing protein
IBG28_RS20725	COG0704	Plays a role in the regulation of phosphate uptake
IBG28_RS20730	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IBG28_RS20735	COG0573	inorganic phosphate transmembrane transporter activity
IBG28_RS20740	COG0573	inorganic phosphate transmembrane transporter activity
IBG28_RS20760	COG0604	alcohol dehydrogenase
IBG28_RS20760	COG1028	Short-chain dehydrogenase reductase Sdr
IBG28_RS20760	COG3321	synthase
IBG28_RS20775	COG0506	proline dehydrogenase activity
IBG28_RS20775	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IBG28_RS20775	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IBG28_RS20780	COG1840	ABC-type Fe3 transport system, periplasmic component
IBG28_RS20815	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
IBG28_RS20820	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
IBG28_RS20825	COG0673	inositol 2-dehydrogenase activity
IBG28_RS20840	COG0210	DNA helicase
IBG28_RS20850	COG1448	Aminotransferase
IBG28_RS20860	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IBG28_RS20865	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IBG28_RS20870	COG2166	iron-sulfur cluster assembly
IBG28_RS20890	COG3097	Belongs to the UPF0267 family
IBG28_RS20895	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IBG28_RS20905	COG0355	proton-transporting ATP synthase activity, rotational mechanism
IBG28_RS20910	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IBG28_RS20915	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IBG28_RS20920	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IBG28_RS20925	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IBG28_RS20930	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IBG28_RS20940	COG0356	it plays a direct role in the translocation of protons across the membrane
IBG28_RS20950	COG1475	DNA binding
IBG28_RS20955	COG1192	Involved in chromosome partitioning
IBG28_RS20960	COG0357	Ribosomal RNA small subunit methyltransferase G
IBG28_RS20965	COG0445	tRNA wobble uridine modification
IBG28_RS20970	COG1064	alcohol dehydrogenase
IBG28_RS20980	COG1309	transcriptional regulator
IBG28_RS20985	COG0604	alcohol dehydrogenase
IBG28_RS20990	COG3835	regulator
IBG28_RS21000	COG1929	Belongs to the glycerate kinase type-1 family
IBG28_RS21005	COG2205	protein histidine kinase activity
IBG28_RS21015	COG0569	domain protein
IBG28_RS21020	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IBG28_RS21035	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IBG28_RS21040	COG0706	membrane insertase activity
IBG28_RS21045	COG0594	ribonuclease P activity
IBG28_RS21050	COG0230	Belongs to the bacterial ribosomal protein bL34 family