locus-tag	class	description
C9I28_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
C9I28_RS00045	COG0583	DNA-binding transcription factor activity
C9I28_RS00050	COG1028	Short-chain dehydrogenase reductase Sdr
C9I28_RS00060	COG0446	pyridine nucleotide-disulphide oxidoreductase
C9I28_RS00065	COG2863	cytochrome
C9I28_RS00070	COG3258	Cytochrome c
C9I28_RS00110	COG0840	transmembrane signaling receptor activity
C9I28_RS00125	COG1404	Belongs to the peptidase S8 family
C9I28_RS00140	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
C9I28_RS00145	COG0784	Response regulator, receiver
C9I28_RS00145	COG2205	protein histidine kinase activity
C9I28_RS00145	COG2198	Histidine kinase
C9I28_RS00155	COG0302	gtp cyclohydrolase
C9I28_RS00160	COG2816	NAD+ diphosphatase activity
C9I28_RS00175	COG0154	amidase activity
C9I28_RS00195	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C9I28_RS00205	COG2089	acid synthase
C9I28_RS00215	COG1083	cytidylyl-transferase
C9I28_RS00220	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C9I28_RS00225	COG1086	Polysaccharide biosynthesis protein
C9I28_RS00230	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C9I28_RS00235	COG2274	protein secretion by the type I secretion system
C9I28_RS00260	COG0745	RESPONSE REGULATOR receiver
C9I28_RS00290	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C9I28_RS00355	COG4792	protein secretion
C9I28_RS00360	COG1684	flagellar biosynthetic protein fliR
C9I28_RS00365	COG4794	Type iii secretion
C9I28_RS00390	COG1157	protein secretion by the type III secretion system
C9I28_RS00410	COG4789	Type iii secretion
C9I28_RS00450	COG0500	methyltransferase
C9I28_RS00490	COG0745	RESPONSE REGULATOR receiver
C9I28_RS00495	COG5002	protein histidine kinase activity
C9I28_RS00525	COG0629	single-stranded DNA binding
C9I28_RS00570	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
C9I28_RS00575	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C9I28_RS00590	COG2974	May be involved in recombination
C9I28_RS00595	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C9I28_RS00605	COG0840	transmembrane signaling receptor activity
C9I28_RS00630	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C9I28_RS00640	COG3634	alkyl hydroperoxide reductase activity
C9I28_RS00645	COG0450	alkyl hydroperoxide reductase
C9I28_RS00660	COG1032	radical SAM domain protein
C9I28_RS00695	COG0339	signal peptide processing
C9I28_RS00700	COG0339	signal peptide processing
C9I28_RS00725	COG2900	Belongs to the SlyX family
C9I28_RS00730	COG0210	DNA helicase
C9I28_RS00760	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C9I28_RS00765	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
C9I28_RS00775	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C9I28_RS00800	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C9I28_RS00805	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C9I28_RS00820	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C9I28_RS00825	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C9I28_RS00830	COG4221	oxidoreductase activity
C9I28_RS00845	COG0140	phosphoribosyl-ATP diphosphatase activity
C9I28_RS00850	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
C9I28_RS00855	COG0107	imidazoleglycerol-phosphate synthase activity
C9I28_RS00860	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
C9I28_RS00875	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
C9I28_RS00885	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
C9I28_RS00890	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
C9I28_RS00895	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C9I28_RS00900	COG0271	Belongs to the BolA IbaG family
C9I28_RS00905	COG0842	Transport permease protein
C9I28_RS00910	COG1131	(ABC) transporter
C9I28_RS00930	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C9I28_RS00935	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
C9I28_RS00940	COG1127	ABC transporter
C9I28_RS00960	COG0069	glutamate synthase activity
C9I28_RS00960	COG0070	glutamate synthase
C9I28_RS00960	COG0067	glutamate synthase
C9I28_RS00980	COG5002	protein histidine kinase activity
C9I28_RS00985	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C9I28_RS00990	COG2183	response to ionizing radiation
C9I28_RS01005	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
C9I28_RS01015	COG2312	Erythromycin esterase
C9I28_RS01025	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C9I28_RS01030	COG0789	Transcriptional regulator
C9I28_RS01035	COG1960	acyl-CoA dehydrogenase activity
C9I28_RS01040	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
C9I28_RS01045	COG0183	Belongs to the thiolase family
C9I28_RS01050	COG0300	oxidoreductase activity
C9I28_RS01055	COG1960	acyl-CoA dehydrogenase activity
C9I28_RS01060	COG0745	RESPONSE REGULATOR receiver
C9I28_RS01075	COG2205	protein histidine kinase activity
C9I28_RS01080	COG1295	ribonuclease BN
C9I28_RS01085	COG0281	malic enzyme
C9I28_RS01085	COG0280	phosphate acetyltransferase
C9I28_RS01090	COG1619	proteins homologs of microcin C7 resistance protein MccF
C9I28_RS01095	COG4206	TonB-dependent receptor
C9I28_RS01105	COG0700	Nucleoside recognition
C9I28_RS01110	COG2027	D-alanyl-D-alanine carboxypeptidase
C9I28_RS01160	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
C9I28_RS01170	COG3023	N-Acetylmuramoyl-L-alanine amidase
C9I28_RS01180	COG1649	PFAM Uncharacterised BCR, COG1649
C9I28_RS01190	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
C9I28_RS01195	COG2188	Transcriptional regulator
C9I28_RS01210	COG3012	SEC-C Motif Domain Protein
C9I28_RS01215	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C9I28_RS01220	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
C9I28_RS01230	COG0156	8-amino-7-oxononanoate synthase activity
C9I28_RS01235	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
C9I28_RS01240	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
C9I28_RS01270	COG0625	glutathione transferase activity
C9I28_RS01275	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
C9I28_RS01285	COG0792	nuclease activity
C9I28_RS01290	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
C9I28_RS01295	COG2823	Periplasmic or secreted lipoprotein
C9I28_RS01300	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C9I28_RS01310	COG1192	Involved in chromosome partitioning
C9I28_RS01320	COG1079	Belongs to the binding-protein-dependent transport system permease family
C9I28_RS01325	COG4603	Belongs to the binding-protein-dependent transport system permease family
C9I28_RS01330	COG3845	ABC transporter
C9I28_RS01335	COG2186	Transcriptional regulator
C9I28_RS01355	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
C9I28_RS01375	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
C9I28_RS01380	COG0321	lipoyl(octanoyl) transferase activity
C9I28_RS01385	COG2921	Belongs to the UPF0250 family
C9I28_RS01395	COG1280	lysine exporter protein (LysE YggA)
C9I28_RS01400	COG2354	Protein conserved in bacteria
C9I28_RS01405	COG0840	transmembrane signaling receptor activity
C9I28_RS01410	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C9I28_RS01420	COG2217	Heavy metal translocating P-type atpase
C9I28_RS01430	COG3278	Belongs to the heme-copper respiratory oxidase family
C9I28_RS01450	COG0348	domain, Protein
C9I28_RS01475	COG1090	epimerase
C9I28_RS01500	COG0583	DNA-binding transcription factor activity
C9I28_RS01505	COG0697	spore germination
C9I28_RS01515	COG2197	response regulator
C9I28_RS01530	COG2353	YceI-like domain
C9I28_RS01545	COG4977	sequence-specific DNA binding
C9I28_RS01580	COG1609	Transcriptional regulator
C9I28_RS01590	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C9I28_RS01605	COG1116	anion transmembrane transporter activity
C9I28_RS01610	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C9I28_RS01615	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C9I28_RS01620	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C9I28_RS01625	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C9I28_RS01640	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C9I28_RS01650	COG0667	Aldo Keto reductase
C9I28_RS01655	COG3829	transcription factor binding
C9I28_RS01690	COG4964	Belongs to the GSP D family
C9I28_RS01715	COG2197	response regulator
C9I28_RS01720	COG4585	Histidine kinase
C9I28_RS01740	COG3321	synthase
C9I28_RS01740	COG0604	alcohol dehydrogenase
C9I28_RS01740	COG1028	Short-chain dehydrogenase reductase Sdr
C9I28_RS01765	COG1309	transcriptional regulator
C9I28_RS01795	COG0625	glutathione transferase activity
C9I28_RS01825	COG1522	sequence-specific DNA binding
C9I28_RS01835	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
C9I28_RS01845	COG0742	ribosomal rna small subunit methyltransferase
C9I28_RS01850	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
C9I28_RS01855	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C9I28_RS01885	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
C9I28_RS01885	COG0506	proline dehydrogenase activity
C9I28_RS01885	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
C9I28_RS01890	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C9I28_RS01895	COG2070	2-Nitropropane dioxygenase
C9I28_RS01900	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
C9I28_RS01905	COG0411	ABC transporter
C9I28_RS01925	COG4214	carbohydrate transport
C9I28_RS01935	COG1454	alcohol dehydrogenase
C9I28_RS01945	COG0445	tRNA wobble uridine modification
C9I28_RS01950	COG0357	Ribosomal RNA small subunit methyltransferase G
C9I28_RS01955	COG1192	Involved in chromosome partitioning
C9I28_RS01960	COG1475	DNA binding
C9I28_RS01970	COG0356	it plays a direct role in the translocation of protons across the membrane
C9I28_RS01985	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
C9I28_RS01990	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
C9I28_RS01995	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
C9I28_RS02000	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
C9I28_RS02005	COG0355	proton-transporting ATP synthase activity, rotational mechanism
C9I28_RS02040	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
C9I28_RS02060	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
C9I28_RS02095	COG0625	glutathione transferase activity
C9I28_RS02100	COG0583	DNA-binding transcription factor activity
C9I28_RS02115	COG3734	2-keto-3-deoxy-galactonokinase
C9I28_RS02120	COG0800	Aldolase
C9I28_RS02155	COG2326	polyphosphate kinase activity
C9I28_RS02185	COG5507	3-demethylubiquinone-9 3-methyltransferase
C9I28_RS02190	COG0512	Glutamine amidotransferase of anthranilate synthase
C9I28_RS02190	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C9I28_RS02200	COG1309	transcriptional regulator
C9I28_RS02220	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
C9I28_RS02250	COG2070	2-Nitropropane dioxygenase
C9I28_RS02260	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
C9I28_RS02410	COG0488	(ABC) transporter
C9I28_RS02430	COG3158	transport of potassium into the cell
C9I28_RS02445	COG0577	efflux transmembrane transporter activity
C9I28_RS02445	COG1136	(ABC) transporter
C9I28_RS02460	COG4191	Histidine kinase
C9I28_RS02465	COG2153	protein acetylation
C9I28_RS02470	COG1764	response to oxidative stress
C9I28_RS02480	COG2918	glutathione biosynthetic process
C9I28_RS02485	COG2890	protein-(glutamine-N5) methyltransferase activity
C9I28_RS02490	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
C9I28_RS02495	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
C9I28_RS02500	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
C9I28_RS02505	COG0745	RESPONSE REGULATOR receiver
C9I28_RS02515	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
C9I28_RS02525	COG0850	regulation of cytokinetic process
C9I28_RS02530	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C9I28_RS02535	COG0583	DNA-binding transcription factor activity
C9I28_RS02545	COG0183	Belongs to the thiolase family
C9I28_RS02550	COG1028	Short-chain dehydrogenase reductase Sdr
C9I28_RS02580	COG0446	pyridine nucleotide-disulphide oxidoreductase
C9I28_RS02580	COG1902	pentaerythritol trinitrate reductase activity
C9I28_RS02585	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C9I28_RS02585	COG4651	solute:proton antiporter activity
C9I28_RS02595	COG0793	Belongs to the peptidase S41A family
C9I28_RS02605	COG4771	TonB-dependent receptor
C9I28_RS02610	COG3590	peptidase
C9I28_RS02615	COG3590	peptidase
C9I28_RS02630	COG2197	response regulator
C9I28_RS02650	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C9I28_RS02655	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C9I28_RS02665	COG2204	response regulator
C9I28_RS02720	COG0367	asparagine synthase
C9I28_RS02725	COG0463	Glycosyl transferase, family 2
C9I28_RS02760	COG0741	lytic transglycosylase activity
C9I28_RS02800	COG0489	protein tyrosine kinase activity
C9I28_RS02810	COG3409	Peptidoglycan-binding domain 1 protein
C9I28_RS02810	COG3267	Type II secretory pathway component ExeA
C9I28_RS02840	COG0438	transferase activity, transferring glycosyl groups
C9I28_RS02845	COG0367	asparagine synthase
C9I28_RS02850	COG0438	transferase activity, transferring glycosyl groups
C9I28_RS02910	COG1686	Belongs to the peptidase S11 family
C9I28_RS02915	COG2945	thiolester hydrolase activity
C9I28_RS02940	COG1127	ABC transporter
C9I28_RS02945	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
C9I28_RS03010	COG2373	Large extracellular alpha-helical protein
C9I28_RS03015	COG5445	Predicted secreted protein (DUF2300)
C9I28_RS03020	COG4676	Protein conserved in bacteria
C9I28_RS03025	COG4676	Protein conserved in bacteria
C9I28_RS03060	COG2366	antibiotic biosynthetic process
C9I28_RS03065	COG2366	antibiotic biosynthetic process
C9I28_RS03095	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
C9I28_RS03100	COG2084	Dehydrogenase
C9I28_RS03105	COG1473	amidohydrolase
C9I28_RS03110	COG0243	molybdopterin cofactor binding
C9I28_RS03120	COG0318	PFAM AMP-dependent synthetase and ligase
C9I28_RS03125	COG0318	PFAM AMP-dependent synthetase and ligase
C9I28_RS03130	COG0583	DNA-binding transcription factor activity
C9I28_RS03145	COG1960	acyl-CoA dehydrogenase activity
C9I28_RS03155	COG3540	Alkaline phosphatase
C9I28_RS03165	COG5265	(ABC) transporter
C9I28_RS03175	COG1301	dicarboxylic acid transport
C9I28_RS03180	COG1126	abc transporter atp-binding protein
C9I28_RS03185	COG0418	dihydroorotase activity
C9I28_RS03210	COG2755	lipolytic protein G-D-S-L family
C9I28_RS03210	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
C9I28_RS03215	COG4771	TonB-dependent receptor
C9I28_RS03220	COG0739	heme binding
C9I28_RS03240	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
C9I28_RS03245	COG0343	queuine tRNA-ribosyltransferase activity
C9I28_RS03250	COG1862	Preprotein translocase
C9I28_RS03260	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C9I28_RS03265	COG2211	Major facilitator Superfamily
C9I28_RS03270	COG3459	Glycosyltransferase 36 associated
C9I28_RS03275	COG3265	gluconokinase activity
C9I28_RS03280	COG1609	Transcriptional regulator
C9I28_RS03295	COG0625	glutathione transferase activity
C9I28_RS03325	COG1846	Transcriptional regulator
C9I28_RS03335	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C9I28_RS03345	COG3138	arginine N-succinyltransferase
C9I28_RS03360	COG2902	Dehydrogenase
C9I28_RS03375	COG1902	pentaerythritol trinitrate reductase activity
C9I28_RS03385	COG0531	amino acid
C9I28_RS03395	COG2814	Major facilitator Superfamily
C9I28_RS03410	COG1940	carbohydrate kinase activity
C9I28_RS03415	COG2222	sugar isomerase
C9I28_RS03430	COG0673	inositol 2-dehydrogenase activity
C9I28_RS03450	COG1289	transmembrane transporter activity
C9I28_RS03460	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
C9I28_RS03465	COG0386	Belongs to the glutathione peroxidase family
C9I28_RS03470	COG0431	NADPH-dependent FMN reductase
C9I28_RS03515	COG2353	YceI-like domain
C9I28_RS03520	COG3038	cytochrome b561
C9I28_RS03530	COG0625	glutathione transferase activity
C9I28_RS03545	COG3128	pkhd-type hydroxylase
C9I28_RS03575	COG4774	siderophore transport
C9I28_RS03585	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C9I28_RS03595	COG0482	sulfurtransferase activity
C9I28_RS03620	COG1609	Transcriptional regulator
C9I28_RS03625	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
C9I28_RS03645	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C9I28_RS03655	COG0432	Pfam Uncharacterised protein family UPF0047
C9I28_RS03660	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C9I28_RS03665	COG0006	proline dipeptidase activity
C9I28_RS03670	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
C9I28_RS03675	COG3178	'Phosphotransferase
C9I28_RS03680	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
C9I28_RS03685	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C9I28_RS03690	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
C9I28_RS03695	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
C9I28_RS03720	COG1420	regulation of RNA biosynthetic process
C9I28_RS03725	COG0735	belongs to the Fur family
C9I28_RS03730	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C9I28_RS03735	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
C9I28_RS03760	COG1881	PFAM PEBP family protein
C9I28_RS03770	COG0024	Methionine aminopeptidase
C9I28_RS03790	COG0495	leucyl-tRNA aminoacylation
C9I28_RS03805	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
C9I28_RS03810	COG1981	membrane
C9I28_RS03825	COG2814	Major facilitator Superfamily
C9I28_RS03830	COG3852	Histidine kinase
C9I28_RS03845	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C9I28_RS03880	COG4206	TonB-dependent receptor
C9I28_RS03905	COG5002	protein histidine kinase activity
C9I28_RS03910	COG0220	tRNA (guanine-N7-)-methyltransferase activity
C9I28_RS03915	COG0697	spore germination
C9I28_RS03925	COG0514	ATP-dependent DNA helicase (RecQ)
C9I28_RS03930	COG1968	undecaprenyl-diphosphatase activity
C9I28_RS03935	COG0596	Alpha beta hydrolase
C9I28_RS03950	COG0297	glycogen (starch) synthase activity
C9I28_RS03955	COG0366	Alpha amylase catalytic
C9I28_RS04000	COG2733	membrane
C9I28_RS04025	COG0346	lactoylglutathione lyase activity
C9I28_RS04065	COG0497	DNA recombination
C9I28_RS04075	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
C9I28_RS04080	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
C9I28_RS04085	COG0443	Heat shock 70 kDa protein
C9I28_RS04090	COG0484	heat shock protein binding
C9I28_RS04095	COG0288	reversible hydration of carbon dioxide
C9I28_RS04105	COG1573	uracil-dna glycosylase
C9I28_RS04110	COG3647	Membrane
C9I28_RS04115	COG2175	clavaminate synthase activity
C9I28_RS04140	COG1116	anion transmembrane transporter activity
C9I28_RS04140	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C9I28_RS04150	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C9I28_RS04155	COG2146	nitrite reductase [NAD(P)H] activity
C9I28_RS04160	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C9I28_RS04165	COG0243	molybdopterin cofactor binding
C9I28_RS04175	COG0395	ABC-type sugar transport system, permease component
C9I28_RS04180	COG1175	transmembrane transport
C9I28_RS04185	COG1653	transport
C9I28_RS04200	COG0745	RESPONSE REGULATOR receiver
C9I28_RS04220	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
C9I28_RS04225	COG0174	glutamine synthetase
C9I28_RS04240	COG0673	inositol 2-dehydrogenase activity
C9I28_RS04250	COG1012	belongs to the aldehyde dehydrogenase family
C9I28_RS04255	COG4771	TonB-dependent receptor
C9I28_RS04265	COG1846	Transcriptional regulator
C9I28_RS04270	COG1063	alcohol dehydrogenase
C9I28_RS04275	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
C9I28_RS04290	COG0617	tRNA 3'-terminal CCA addition
C9I28_RS04300	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
C9I28_RS04305	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
C9I28_RS04320	COG0205	6-phosphofructokinase activity
C9I28_RS04325	COG2366	antibiotic biosynthetic process
C9I28_RS04360	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
C9I28_RS04365	COG2137	regulation of response to DNA damage stimulus
C9I28_RS04380	COG0045	succinate-CoA ligase (ADP-forming) activity
C9I28_RS04385	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C9I28_RS04395	COG4969	Belongs to the N-Me-Phe pilin family
C9I28_RS04415	COG0315	cyclic pyranopterin monophosphate synthase activity
C9I28_RS04430	COG0429	hydrolase of the alpha beta-hydrolase fold
C9I28_RS04455	COG0126	phosphoglycerate kinase activity
C9I28_RS04460	COG0469	pyruvate kinase activity
C9I28_RS04470	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
C9I28_RS04475	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
C9I28_RS04480	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C9I28_RS04485	COG0009	L-threonylcarbamoyladenylate synthase
C9I28_RS04510	COG5002	protein histidine kinase activity
C9I28_RS04515	COG1960	acyl-CoA dehydrogenase activity
C9I28_RS04520	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C9I28_RS04525	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
C9I28_RS04530	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C9I28_RS04540	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
C9I28_RS04545	COG0259	pyridoxamine-phosphate oxidase activity
C9I28_RS04550	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
C9I28_RS04600	COG1546	Belongs to the CinA family
C9I28_RS04605	COG0784	Response regulator, receiver
C9I28_RS04605	COG2205	protein histidine kinase activity
C9I28_RS04605	COG5002	protein histidine kinase activity
C9I28_RS04675	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
C9I28_RS04680	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C9I28_RS04700	COG2205	protein histidine kinase activity
C9I28_RS04700	COG0784	Response regulator, receiver
C9I28_RS04705	COG2271	Major facilitator Superfamily
C9I28_RS04725	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C9I28_RS04735	COG2186	Transcriptional regulator
C9I28_RS04745	COG1349	DNA-binding transcription factor activity
C9I28_RS04750	COG0738	Major facilitator superfamily
C9I28_RS04845	COG0254	rRNA binding
C9I28_RS04850	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
C9I28_RS04860	COG0745	RESPONSE REGULATOR receiver
C9I28_RS04875	COG2169	Transcriptional regulator
C9I28_RS04875	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C9I28_RS04895	COG1574	metal-dependent hydrolase with the TIM-barrel fold
C9I28_RS04900	COG0667	Aldo Keto reductase
C9I28_RS04905	COG0583	DNA-binding transcription factor activity
C9I28_RS04910	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
C9I28_RS04915	COG2986	histidine ammonia-lyase
C9I28_RS04935	COG1228	amidohydrolase
C9I28_RS05010	COG1335	isochorismatase
C9I28_RS05025	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
C9I28_RS05060	COG2094	Belongs to the DNA glycosylase MPG family
C9I28_RS05065	COG0840	transmembrane signaling receptor activity
C9I28_RS05075	COG1509	lysine 2,3-aminomutase activity
C9I28_RS05090	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C9I28_RS05110	COG0521	Mo-molybdopterin cofactor biosynthetic process
C9I28_RS05115	COG3028	Belongs to the UPF0307 family
C9I28_RS05120	COG0312	modulator of DNA gyrase
C9I28_RS05125	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
C9I28_RS05155	COG2866	Carboxypeptidase
C9I28_RS05160	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
C9I28_RS05170	COG3396	Phenylacetate-CoA oxygenase
C9I28_RS05175	COG3460	Phenylacetate-CoA oxygenase
C9I28_RS05180	COG3396	Phenylacetate-CoA oxygenase
C9I28_RS05185	COG2151	metal-sulfur cluster biosynthetic enzyme
C9I28_RS05190	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C9I28_RS05195	COG1024	Enoyl-CoA hydratase
C9I28_RS05200	COG1250	3-hydroxyacyl-CoA dehydrogenase
C9I28_RS05205	COG2050	protein possibly involved in aromatic compounds catabolism
C9I28_RS05215	COG0183	Belongs to the thiolase family
C9I28_RS05225	COG1012	belongs to the aldehyde dehydrogenase family
C9I28_RS05225	COG2030	dehydratase
C9I28_RS05265	COG0165	Argininosuccinate lyase
C9I28_RS05280	COG4206	TonB-dependent receptor
C9I28_RS05340	COG0187	DNA topoisomerase II activity
C9I28_RS05355	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
C9I28_RS05360	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
C9I28_RS05370	COG2205	protein histidine kinase activity
C9I28_RS05375	COG0745	RESPONSE REGULATOR receiver
C9I28_RS05405	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C9I28_RS05430	COG0494	nUDIX hydrolase
C9I28_RS05435	COG0442	prolyl-tRNA aminoacylation
C9I28_RS05440	COG0741	lytic transglycosylase activity
C9I28_RS05450	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C9I28_RS05455	COG4269	membrane
C9I28_RS05460	COG0501	Belongs to the peptidase M48B family
C9I28_RS05475	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C9I28_RS05480	COG1116	anion transmembrane transporter activity
C9I28_RS05485	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C9I28_RS05510	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C9I28_RS05525	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C9I28_RS05535	COG3209	COG3209 Rhs family protein
C9I28_RS05590	COG1459	type II secretion system
C9I28_RS05595	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C9I28_RS05620	COG0762	integral membrane protein
C9I28_RS05625	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C9I28_RS05635	COG2264	protein methyltransferase activity
C9I28_RS05640	COG0439	Biotin carboxylase
C9I28_RS05645	COG0511	ligase activity, forming carbon-carbon bonds
C9I28_RS05650	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
C9I28_RS05665	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C9I28_RS05670	COG3150	esterase
C9I28_RS05675	COG3161	chorismate lyase activity
C9I28_RS05680	COG0557	exoribonuclease II activity
C9I28_RS05690	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
C9I28_RS05695	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C9I28_RS05700	COG0598	Magnesium transport protein CorA
C9I28_RS05710	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
C9I28_RS05715	COG0351	phosphomethylpyrimidine kinase
C9I28_RS05720	COG1773	rubredoxin
C9I28_RS05745	COG2198	Histidine kinase
C9I28_RS05745	COG0643	Histidine kinase
C9I28_RS05745	COG0784	Response regulator, receiver
C9I28_RS05755	COG0415	Belongs to the DNA photolyase family
C9I28_RS05760	COG1678	Uncharacterized ACR, COG1678
C9I28_RS05765	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
C9I28_RS05770	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
C9I28_RS05775	COG0540	Belongs to the ATCase OTCase family
C9I28_RS05790	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C9I28_RS05800	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
C9I28_RS05815	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C9I28_RS05840	COG0454	-acetyltransferase
C9I28_RS05840	COG0456	acetyltransferase
C9I28_RS05855	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
C9I28_RS05860	COG0751	glycine-tRNA ligase activity
C9I28_RS05865	COG0752	glycyl-tRNA synthetase alpha subunit
C9I28_RS05870	COG0815	Transfers the fatty acyl group on membrane lipoproteins
C9I28_RS05875	COG4535	Mg2 and Co2 transporter CorC
C9I28_RS05900	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
C9I28_RS05905	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C9I28_RS05910	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
C9I28_RS05915	COG1702	phosphate starvation-inducible protein PhoH
C9I28_RS05920	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C9I28_RS05945	COG4191	Histidine kinase
C9I28_RS05945	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C9I28_RS05965	COG1690	Belongs to the RtcB family
C9I28_RS05970	COG0430	RNA-3'-phosphate cyclase activity
C9I28_RS05975	COG4772	TonB-dependent receptor
C9I28_RS06010	COG0477	Major facilitator Superfamily
C9I28_RS06015	COG1492	cobalamin metabolic process
C9I28_RS06020	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C9I28_RS06030	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
C9I28_RS06040	COG1797	cobyrinic acid a,c-diamide synthase activity
C9I28_RS06055	COG1120	ATPase activity
C9I28_RS06060	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C9I28_RS06065	COG4206	TonB-dependent receptor
C9I28_RS06075	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
C9I28_RS06080	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
C9I28_RS06085	COG0745	RESPONSE REGULATOR receiver
C9I28_RS06095	COG2194	sulfuric ester hydrolase activity
C9I28_RS06175	COG0347	Belongs to the P(II) protein family
C9I28_RS06180	COG0004	ammonium transporteR
C9I28_RS06190	COG0189	ligase activity
C9I28_RS06205	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C9I28_RS06210	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
C9I28_RS06215	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
C9I28_RS06215	COG2813	Specifically methylates the guanine in position
C9I28_RS06225	COG0564	pseudouridine synthase activity
C9I28_RS06230	COG0708	Exodeoxyribonuclease III
C9I28_RS06235	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
C9I28_RS06255	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
C9I28_RS06270	COG2267	carboxylic ester hydrolase activity
C9I28_RS06290	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C9I28_RS06295	COG0154	amidase activity
C9I28_RS06300	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C9I28_RS06305	COG1077	Cell shape determining protein MreB Mrl
C9I28_RS06320	COG0768	penicillin binding
C9I28_RS06325	COG0772	Belongs to the SEDS family
C9I28_RS06340	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
C9I28_RS06350	COG0300	oxidoreductase activity
C9I28_RS06355	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C9I28_RS06365	COG0018	arginyl-trna synthetase
C9I28_RS06380	COG5000	phosphorelay sensor kinase activity
C9I28_RS06385	COG2204	response regulator
C9I28_RS06385	COG2204	response regulator
C9I28_RS06400	COG0121	glutamine amidotransferase
C9I28_RS06405	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
C9I28_RS06420	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
C9I28_RS06425	COG0242	peptide deformylase activity
C9I28_RS06435	COG0758	DNA mediated transformation
C9I28_RS06440	COG2922	Belongs to the Smg family
C9I28_RS06455	COG0840	transmembrane signaling receptor activity
C9I28_RS06475	COG1131	(ABC) transporter
C9I28_RS06485	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
C9I28_RS06490	COG2321	neutral zinc metallopeptidase
C9I28_RS06495	COG0572	uridine kinase
C9I28_RS06505	COG1765	OsmC-like protein
C9I28_RS06515	COG4555	ABC transporter
C9I28_RS06525	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
C9I28_RS06530	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
C9I28_RS06535	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
C9I28_RS06540	COG0316	Belongs to the HesB IscA family
C9I28_RS06560	COG0741	lytic transglycosylase activity
C9I28_RS06560	COG1196	nuclear chromosome segregation
C9I28_RS06560	COG0739	heme binding
C9I28_RS06565	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C9I28_RS06570	COG1490	D-aminoacyl-tRNA deacylase activity
C9I28_RS06585	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C9I28_RS06590	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
C9I28_RS06595	COG0138	bifunctional purine biosynthesis protein purh
C9I28_RS06600	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
C9I28_RS06605	COG0632	four-way junction helicase activity
C9I28_RS06610	COG2255	four-way junction helicase activity
C9I28_RS06615	COG1671	Belongs to the UPF0178 family
C9I28_RS06640	COG0525	valine-tRNA ligase activity
C9I28_RS06650	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
C9I28_RS06660	COG2022	thiamine diphosphate biosynthetic process
C9I28_RS06665	COG0351	phosphomethylpyrimidine kinase
C9I28_RS06670	COG0352	thiamine-phosphate diphosphorylase activity
C9I28_RS06675	COG0745	RESPONSE REGULATOR receiver
C9I28_RS06695	COG0210	DNA helicase
C9I28_RS06705	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C9I28_RS06735	COG0412	Dienelactone hydrolase
C9I28_RS06770	COG1722	exodeoxyribonuclease VII activity
C9I28_RS06775	COG0142	geranyltranstransferase activity
C9I28_RS06780	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
C9I28_RS06800	COG3275	phosphorelay sensor kinase activity
C9I28_RS06815	COG2096	Adenosyltransferase
C9I28_RS06820	COG0277	FAD linked oxidase domain protein
C9I28_RS06825	COG0277	FAD linked oxidase domain protein
C9I28_RS06830	COG0247	lactate metabolic process
C9I28_RS06840	COG0386	Belongs to the glutathione peroxidase family
C9I28_RS06855	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
C9I28_RS06875	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
C9I28_RS06880	COG0583	DNA-binding transcription factor activity
C9I28_RS06885	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
C9I28_RS06910	COG2226	methyltransferase
C9I28_RS06925	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
C9I28_RS06960	COG0109	protoheme IX farnesyltransferase activity
C9I28_RS06965	COG1999	signal sequence binding
C9I28_RS06975	COG0628	permease
C9I28_RS06985	COG1253	flavin adenine dinucleotide binding
C9I28_RS06990	COG0583	DNA-binding transcription factor activity
C9I28_RS07030	COG1595	DNA-templated transcription, initiation
C9I28_RS07045	COG1131	(ABC) transporter
C9I28_RS07050	COG0681	Belongs to the peptidase S26 family
C9I28_RS07055	COG0640	Transcriptional regulator
C9I28_RS07080	COG0405	Gamma-glutamyltransferase
C9I28_RS07090	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C9I28_RS07100	COG2177	Part of the ABC transporter FtsEX involved in
C9I28_RS07130	COG0840	transmembrane signaling receptor activity
C9I28_RS07190	COG2001	Belongs to the MraZ family
C9I28_RS07195	COG0275	rRNA processing
C9I28_RS07200	COG3116	cell division
C9I28_RS07210	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C9I28_RS07215	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C9I28_RS07220	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C9I28_RS07225	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
C9I28_RS07235	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
C9I28_RS07240	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C9I28_RS07245	COG1181	Belongs to the D-alanine--D-alanine ligase family
C9I28_RS07250	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
C9I28_RS07265	COG0678	peroxiredoxin activity
C9I28_RS07270	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
C9I28_RS07290	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
C9I28_RS07300	COG0653	protein targeting
C9I28_RS07305	COG0840	transmembrane signaling receptor activity
C9I28_RS07340	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
C9I28_RS07350	COG0494	nUDIX hydrolase
C9I28_RS07360	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
C9I28_RS07365	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
C9I28_RS07370	COG0237	dephospho-CoA kinase activity
C9I28_RS07375	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
C9I28_RS07410	COG4536	flavin adenine dinucleotide binding
C9I28_RS07420	COG2351	hydroxyisourate hydrolase activity
C9I28_RS07445	COG1529	Aldehyde oxidase and xanthine dehydrogenase
C9I28_RS07455	COG0402	S-adenosylhomocysteine deaminase activity
C9I28_RS07460	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
C9I28_RS07470	COG0737	Belongs to the 5'-nucleotidase family
C9I28_RS07490	COG0494	nUDIX hydrolase
C9I28_RS07500	COG1079	Belongs to the binding-protein-dependent transport system permease family
C9I28_RS07505	COG4603	Belongs to the binding-protein-dependent transport system permease family
C9I28_RS07510	COG3845	ABC transporter
C9I28_RS07515	COG1744	ABC transporter substrate-binding protein PnrA-like
C9I28_RS07535	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
C9I28_RS07540	COG0583	DNA-binding transcription factor activity
C9I28_RS07545	COG2313	pseudouridylate synthase activity
C9I28_RS07550	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C9I28_RS07550	COG1522	sequence-specific DNA binding
C9I28_RS07555	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
C9I28_RS07560	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
C9I28_RS07565	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
C9I28_RS07570	COG1012	belongs to the aldehyde dehydrogenase family
C9I28_RS07595	COG3279	Response regulator of the LytR AlgR family
C9I28_RS07600	COG3275	phosphorelay sensor kinase activity
C9I28_RS07620	COG1309	transcriptional regulator
C9I28_RS07625	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C9I28_RS07630	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C9I28_RS07635	COG0686	Belongs to the AlaDH PNT family
C9I28_RS07655	COG1953	Uracil, thiamine, allantoin
C9I28_RS07685	COG5652	VanZ like family
C9I28_RS07690	COG0583	DNA-binding transcription factor activity
C9I28_RS07700	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C9I28_RS07705	COG3415	Transposase
C9I28_RS07705	COG2801	Transposase and inactivated derivatives
C9I28_RS07710	COG4946	Tricorn protease homolog
C9I28_RS07710	COG1506	peptidase
C9I28_RS07710	COG0823	Involved in the tonB-independent uptake of proteins
C9I28_RS07730	COG2205	protein histidine kinase activity
C9I28_RS07730	COG0784	Response regulator, receiver
C9I28_RS07735	COG2205	protein histidine kinase activity
C9I28_RS07735	COG2198	Histidine kinase
C9I28_RS07735	COG0784	Response regulator, receiver
C9I28_RS07745	COG2172	sigma factor antagonist activity
C9I28_RS07750	COG1366	Belongs to the anti-sigma-factor antagonist family
C9I28_RS07755	COG1366	Belongs to the anti-sigma-factor antagonist family
C9I28_RS07785	COG1705	Flagellar rod assembly protein muramidase FlgJ
C9I28_RS07785	COG3951	Flagellar rod assembly protein muramidase FlgJ
C9I28_RS07815	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
C9I28_RS07835	COG4263	nitrous-oxide reductase activity
C9I28_RS07860	COG3634	alkyl hydroperoxide reductase activity
C9I28_RS07875	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C9I28_RS07890	COG3291	Pkd domain containing protein
C9I28_RS07895	COG0484	heat shock protein binding
C9I28_RS07900	COG4178	(ABC) transporter
C9I28_RS07910	COG1393	Belongs to the ArsC family
C9I28_RS07930	COG4677	pectinesterase activity
C9I28_RS07935	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
C9I28_RS07940	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
C9I28_RS07940	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
C9I28_RS07945	COG2186	Transcriptional regulator
C9I28_RS07950	COG0142	geranyltranstransferase activity
C9I28_RS07955	COG0261	This protein binds to 23S rRNA in the presence of protein L20
C9I28_RS07960	COG0211	Belongs to the bacterial ribosomal protein bL27 family
C9I28_RS07965	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
C9I28_RS07970	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
C9I28_RS07975	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C9I28_RS07980	COG2878	Part of a membrane complex involved in electron transport
C9I28_RS07995	COG0492	ferredoxin-NADP+ reductase activity
C9I28_RS08000	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
C9I28_RS08030	COG0776	regulation of translation
C9I28_RS08095	COG0174	glutamine synthetase
C9I28_RS08105	COG3852	Histidine kinase
C9I28_RS08115	COG0598	Magnesium transport protein CorA
C9I28_RS08120	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
C9I28_RS08130	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C9I28_RS08140	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C9I28_RS08155	COG4771	TonB-dependent receptor
C9I28_RS08160	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
C9I28_RS08170	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C9I28_RS08175	COG0312	modulator of DNA gyrase
C9I28_RS08185	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C9I28_RS08200	COG4206	TonB-dependent receptor
C9I28_RS08205	COG4206	TonB-dependent receptor
C9I28_RS08210	COG4206	TonB-dependent receptor
C9I28_RS08215	COG0601	transmembrane transport
C9I28_RS08220	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C9I28_RS08235	COG1737	Transcriptional regulator
C9I28_RS08235	COG0837	glucose binding
C9I28_RS08240	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
C9I28_RS08250	COG0779	Required for maturation of 30S ribosomal subunits
C9I28_RS08255	COG2251	uridine kinase activity
C9I28_RS08255	COG0195	Participates in both transcription termination and antitermination
C9I28_RS08260	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
C9I28_RS08265	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
C9I28_RS08285	COG2205	protein histidine kinase activity
C9I28_RS08300	COG1070	Carbohydrate kinase
C9I28_RS08315	COG1129	ABC transporter
C9I28_RS08330	COG1028	Short-chain dehydrogenase reductase Sdr
C9I28_RS08330	COG3347	Dehydrogenase
C9I28_RS08335	COG4952	isomerase
C9I28_RS08345	COG3254	rhamnose metabolic process
C9I28_RS08365	COG2755	lipolytic protein G-D-S-L family
C9I28_RS08370	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
C9I28_RS08380	COG3401	FG-GAP repeat protein
C9I28_RS08390	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C9I28_RS08395	COG0840	transmembrane signaling receptor activity
C9I28_RS08435	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
C9I28_RS08450	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C9I28_RS08465	COG5652	VanZ like family
C9I28_RS08530	COG5001	Diguanylate cyclase
C9I28_RS08540	COG0840	transmembrane signaling receptor activity
C9I28_RS08565	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C9I28_RS08630	COG2814	Major facilitator Superfamily
C9I28_RS08635	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C9I28_RS08640	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C9I28_RS08640	COG2205	protein histidine kinase activity
C9I28_RS08665	COG4771	TonB-dependent receptor
C9I28_RS08670	COG1028	Short-chain dehydrogenase reductase Sdr
C9I28_RS08685	COG1704	LemA family
C9I28_RS08690	COG0284	orotidine-5'-phosphate decarboxylase activity
C9I28_RS08695	COG2925	Exonuclease
C9I28_RS08705	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C9I28_RS08765	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C9I28_RS08770	COG0484	heat shock protein binding
C9I28_RS08810	COG0583	DNA-binding transcription factor activity
C9I28_RS08815	COG2814	Major facilitator Superfamily
C9I28_RS08830	COG2814	Major facilitator Superfamily
C9I28_RS08835	COG0656	L-ascorbic acid biosynthetic process
C9I28_RS08840	COG0673	inositol 2-dehydrogenase activity
C9I28_RS08845	COG4702	Belongs to the UPF0303 family
C9I28_RS08850	COG1804	L-carnitine dehydratase bile acid-inducible protein F
C9I28_RS08855	COG0584	glycerophosphoryl diester phosphodiesterase
C9I28_RS08865	COG0425	Belongs to the sulfur carrier protein TusA family
C9I28_RS08870	COG2086	electron transfer activity
C9I28_RS08880	COG1960	acyl-CoA dehydrogenase activity
C9I28_RS08910	COG0228	four-way junction DNA binding
C9I28_RS08915	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
C9I28_RS08920	COG0336	Belongs to the RNA methyltransferase TrmD family
C9I28_RS08925	COG0335	large ribosomal subunit rRNA binding
C9I28_RS08930	COG0494	nUDIX hydrolase
C9I28_RS08935	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
C9I28_RS08945	COG0612	Peptidase, M16
C9I28_RS08950	COG2188	Transcriptional regulator
C9I28_RS08995	COG0395	ABC-type sugar transport system, permease component
C9I28_RS09000	COG1175	transmembrane transport
C9I28_RS09010	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C9I28_RS09020	COG2188	Transcriptional regulator
C9I28_RS09025	COG2971	BadF BadG BcrA BcrD
C9I28_RS09050	COG3267	Type II secretory pathway component ExeA
C9I28_RS09050	COG3409	Peptidoglycan-binding domain 1 protein
C9I28_RS09060	COG1763	Mo-molybdopterin cofactor biosynthetic process
C9I28_RS09075	COG3220	belongs to the UPF0276 family
C9I28_RS09095	COG0114	fumarate hydratase activity
C9I28_RS09120	COG3590	peptidase
C9I28_RS09160	COG0583	DNA-binding transcription factor activity
C9I28_RS09165	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
C9I28_RS09175	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
C9I28_RS09210	COG2274	protein secretion by the type I secretion system
C9I28_RS09260	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C9I28_RS09280	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
C9I28_RS09290	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
C9I28_RS09295	COG0287	Prephenate dehydrogenase
C9I28_RS09300	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
C9I28_RS09305	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
C9I28_RS09315	COG0776	regulation of translation
C9I28_RS09325	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
C9I28_RS09330	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
C9I28_RS09345	COG0492	ferredoxin-NADP+ reductase activity
C9I28_RS09350	COG3842	ATPase activity
C9I28_RS09365	COG2951	lytic endotransglycosylase activity
C9I28_RS09380	COG0714	Associated with various cellular activities
C9I28_RS09385	COG0123	including yeast histone deacetylase and acetoin utilization protein
C9I28_RS09395	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
C9I28_RS09400	COG3384	dioxygenase
C9I28_RS09415	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C9I28_RS09425	COG1472	Belongs to the glycosyl hydrolase 3 family
C9I28_RS09430	COG4214	carbohydrate transport
C9I28_RS09435	COG1129	ABC transporter
C9I28_RS09440	COG0129	dihydroxy-acid dehydratase activity
C9I28_RS09460	COG4948	Mandelate Racemase Muconate Lactonizing
C9I28_RS09475	COG3661	Belongs to the glycosyl hydrolase 67 family
C9I28_RS09520	COG1028	Short-chain dehydrogenase reductase Sdr
C9I28_RS09535	COG1028	Short-chain dehydrogenase reductase Sdr
C9I28_RS09540	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C9I28_RS09545	COG1570	exodeoxyribonuclease VII activity
C9I28_RS09550	COG0811	peptide transport
C9I28_RS09555	COG0848	biopolymer transport protein
C9I28_RS09560	COG1663	tetraacyldisaccharide 4'-kinase activity
C9I28_RS09565	COG2835	tetraacyldisaccharide 4'-kinase activity
C9I28_RS09570	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
C9I28_RS09575	COG0563	adenylate kinase activity
C9I28_RS09595	COG0405	Gamma-glutamyltransferase
C9I28_RS09610	COG0745	RESPONSE REGULATOR receiver
C9I28_RS09630	COG1024	Enoyl-CoA hydratase
C9I28_RS09635	COG1960	acyl-CoA dehydrogenase activity
C9I28_RS09660	COG0488	(ABC) transporter
C9I28_RS09725	COG1216	Glycosyl transferase, family 2
C9I28_RS09750	COG0438	transferase activity, transferring glycosyl groups
C9I28_RS09775	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C9I28_RS09780	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
C9I28_RS09855	COG1450	Type ii and iii secretion system protein
C9I28_RS09880	COG0728	peptidoglycan biosynthetic process
C9I28_RS09885	COG0268	Binds directly to 16S ribosomal RNA
C9I28_RS09895	COG1187	pseudouridine synthase activity
C9I28_RS09905	COG1794	racemase activity, acting on amino acids and derivatives
C9I28_RS09910	COG2205	protein histidine kinase activity
C9I28_RS09915	COG1278	Cold shock
C9I28_RS09920	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
C9I28_RS09925	COG0542	response to heat
C9I28_RS09940	COG0793	Belongs to the peptidase S41A family
C9I28_RS09940	COG4946	Tricorn protease homolog
C9I28_RS09945	COG3279	Response regulator of the LytR AlgR family
C9I28_RS09950	COG3275	phosphorelay sensor kinase activity
C9I28_RS09955	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
C9I28_RS09965	COG3829	transcription factor binding
C9I28_RS10020	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
C9I28_RS10085	COG0175	sulfate reduction
C9I28_RS10095	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C9I28_RS10100	COG0583	DNA-binding transcription factor activity
C9I28_RS10130	COG3275	phosphorelay sensor kinase activity
C9I28_RS10180	COG2070	2-Nitropropane dioxygenase
C9I28_RS10185	COG1666	GTP binding
C9I28_RS10190	COG0812	UDP-N-acetylmuramate dehydrogenase activity
C9I28_RS10195	COG2203	Gaf domain
C9I28_RS10195	COG3706	GGDEF domain
C9I28_RS10195	COG5001	Diguanylate cyclase
C9I28_RS10195	COG4251	negative regulation of phosphorylation
C9I28_RS10200	COG2201	protein-glutamate methylesterase activity
C9I28_RS10220	COG0835	chemotaxis
C9I28_RS10225	COG0840	transmembrane signaling receptor activity
C9I28_RS10230	COG0137	argininosuccinate synthase activity
C9I28_RS10240	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
C9I28_RS10250	COG1162	GTPase activity
C9I28_RS10255	COG0501	Belongs to the peptidase M48B family
C9I28_RS10260	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
C9I28_RS10265	COG3012	SEC-C Motif Domain Protein
C9I28_RS10265	COG3318	Belongs to the UPF0149 family
C9I28_RS10295	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C9I28_RS10315	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
C9I28_RS10365	COG5002	protein histidine kinase activity
C9I28_RS10370	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
C9I28_RS10380	COG2814	Major facilitator Superfamily
C9I28_RS10385	COG5002	protein histidine kinase activity
C9I28_RS10395	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C9I28_RS10400	COG2311	Membrane
C9I28_RS10410	COG1739	Uncharacterized protein family UPF0029
C9I28_RS10485	COG0823	Involved in the tonB-independent uptake of proteins
C9I28_RS10505	COG0824	Thioesterase
C9I28_RS10510	COG4221	oxidoreductase activity
C9I28_RS10515	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
C9I28_RS10520	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
C9I28_RS10555	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C9I28_RS10555	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C9I28_RS10605	COG1764	response to oxidative stress
C9I28_RS10630	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
C9I28_RS10635	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C9I28_RS10655	COG0741	lytic transglycosylase activity
C9I28_RS10660	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
C9I28_RS10675	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C9I28_RS10680	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
C9I28_RS10690	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
C9I28_RS10710	COG2879	small protein
C9I28_RS10715	COG1966	Carbon starvation protein
C9I28_RS10730	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
C9I28_RS10800	COG5001	Diguanylate cyclase
C9I28_RS10800	COG3300	MHYT domain
C9I28_RS10805	COG2610	gluconate transmembrane transporter activity
C9I28_RS10860	COG1597	lipid kinase activity
C9I28_RS10865	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
C9I28_RS10870	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C9I28_RS10880	COG0427	acetyl-CoA hydrolase
C9I28_RS10890	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C9I28_RS10940	COG2982	Protein involved in outer membrane biogenesis
C9I28_RS11005	COG0628	permease
C9I28_RS11015	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
C9I28_RS11015	COG2885	chlorophyll binding
C9I28_RS11060	COG3622	Belongs to the hyi family
C9I28_RS11065	COG0513	Belongs to the DEAD box helicase family
C9I28_RS11070	COG0483	inositol monophosphate 1-phosphatase activity
C9I28_RS11085	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
C9I28_RS11090	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
C9I28_RS11105	COG1309	transcriptional regulator
C9I28_RS11115	COG0625	glutathione transferase activity
C9I28_RS11120	COG1451	nucleotide metabolic process
C9I28_RS11125	COG0322	excinuclease ABC activity
C9I28_RS11145	COG0154	amidase activity
C9I28_RS11155	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
C9I28_RS11160	COG4149	molybdate abc transporter
C9I28_RS11260	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C9I28_RS11265	COG2824	Alkylphosphonate utilization operon protein PhnA
C9I28_RS11275	COG5652	VanZ like family
C9I28_RS11285	COG0181	hydroxymethylbilane synthase activity
C9I28_RS11295	COG2959	enzyme of heme biosynthesis
C9I28_RS11305	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
C9I28_RS11315	COG4771	TonB-dependent receptor
C9I28_RS11320	COG3119	arylsulfatase activity
C9I28_RS11335	COG0840	transmembrane signaling receptor activity
C9I28_RS11355	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C9I28_RS11355	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
C9I28_RS11360	COG0347	Belongs to the P(II) protein family
C9I28_RS11365	COG2860	membrane
C9I28_RS11375	COG0492	ferredoxin-NADP+ reductase activity
C9I28_RS11380	COG1674	ftsk spoiiie
C9I28_RS11385	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
C9I28_RS11390	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C9I28_RS11415	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
C9I28_RS11425	COG3209	COG3209 Rhs family protein
C9I28_RS11485	COG0437	4 iron, 4 sulfur cluster binding
C9I28_RS11535	COG4771	TonB-dependent receptor
C9I28_RS11545	COG2205	protein histidine kinase activity
C9I28_RS11545	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C9I28_RS11560	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C9I28_RS11580	COG4221	oxidoreductase activity
C9I28_RS11580	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C9I28_RS11580	COG0604	alcohol dehydrogenase
C9I28_RS11580	COG3321	synthase
C9I28_RS11595	COG4221	oxidoreductase activity
C9I28_RS11610	COG0612	Peptidase, M16
C9I28_RS11615	COG1607	acyl-coa hydrolase
C9I28_RS11630	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
C9I28_RS11690	COG0248	Ppx GppA phosphatase
C9I28_RS11700	COG5002	protein histidine kinase activity
C9I28_RS11700	COG2205	protein histidine kinase activity
C9I28_RS11700	COG0784	Response regulator, receiver
C9I28_RS11725	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C9I28_RS11735	COG1136	(ABC) transporter
C9I28_RS11740	COG3639	organic phosphonate transmembrane transporter activity
C9I28_RS11745	COG3639	organic phosphonate transmembrane transporter activity
C9I28_RS11760	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
C9I28_RS11765	COG1262	PFAM Formylglycine-generating sulfatase enzyme
C9I28_RS11770	COG3415	Transposase
C9I28_RS11770	COG2801	Transposase and inactivated derivatives
C9I28_RS11775	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C9I28_RS11790	COG1262	PFAM Formylglycine-generating sulfatase enzyme
C9I28_RS11805	COG1506	peptidase
C9I28_RS11805	COG0823	Involved in the tonB-independent uptake of proteins
C9I28_RS11810	COG0753	catalase activity
C9I28_RS11815	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C9I28_RS11820	COG0583	DNA-binding transcription factor activity
C9I28_RS11840	COG4942	peptidase
C9I28_RS11845	COG1376	ErfK ybiS ycfS ynhG family protein
C9I28_RS11850	COG0513	Belongs to the DEAD box helicase family
C9I28_RS11860	COG1388	LysM domain
C9I28_RS11860	COG0741	lytic transglycosylase activity
C9I28_RS11910	COG0840	transmembrane signaling receptor activity
C9I28_RS11915	COG3706	GGDEF domain
C9I28_RS11945	COG0693	protein deglycase activity
C9I28_RS11950	COG4977	sequence-specific DNA binding
C9I28_RS11955	COG1214	PFAM Peptidase M22, glycoprotease
C9I28_RS11960	COG0456	acetyltransferase
C9I28_RS11975	COG0477	Major facilitator Superfamily
C9I28_RS11980	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C9I28_RS12020	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C9I28_RS12025	COG0573	inorganic phosphate transmembrane transporter activity
C9I28_RS12035	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C9I28_RS12040	COG0704	Plays a role in the regulation of phosphate uptake
C9I28_RS12050	COG5002	protein histidine kinase activity
C9I28_RS12055	COG1752	Esterase of the alpha-beta hydrolase superfamily
C9I28_RS12060	COG3193	protein, possibly involved in utilization of glycolate and propanediol
C9I28_RS12090	COG0505	Belongs to the CarA family
C9I28_RS12100	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C9I28_RS12115	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
C9I28_RS12120	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C9I28_RS12125	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
C9I28_RS12130	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C9I28_RS12220	COG0243	molybdopterin cofactor binding
C9I28_RS12220	COG3383	formate dehydrogenase (NAD+) activity
C9I28_RS12225	COG0437	4 iron, 4 sulfur cluster binding
C9I28_RS12245	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
C9I28_RS12260	COG0583	DNA-binding transcription factor activity
C9I28_RS12280	COG3279	Response regulator of the LytR AlgR family
C9I28_RS12305	COG4191	Histidine kinase
C9I28_RS12335	COG0557	exoribonuclease II activity
C9I28_RS12340	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C9I28_RS12345	COG1045	serine acetyltransferase
C9I28_RS12350	COG3132	Protein of unknown function, DUF480
C9I28_RS12365	COG1131	(ABC) transporter
C9I28_RS12370	COG1725	Transcriptional regulator
C9I28_RS12400	COG2226	methyltransferase
C9I28_RS12410	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C9I28_RS12415	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C9I28_RS12425	COG0215	cysteine-tRNA ligase activity
C9I28_RS12435	COG0825	malonyl-CoA metabolic process
C9I28_RS12440	COG0037	tRNA processing
C9I28_RS12445	COG0527	aspartate kinase activity
C9I28_RS12505	COG2267	carboxylic ester hydrolase activity
C9I28_RS12510	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
C9I28_RS12525	COG0840	transmembrane signaling receptor activity
C9I28_RS12530	COG0628	permease
C9I28_RS12540	COG0840	transmembrane signaling receptor activity
C9I28_RS12585	COG1234	tRNA 3'-trailer cleavage
C9I28_RS12610	COG4206	TonB-dependent receptor
C9I28_RS12630	COG0840	transmembrane signaling receptor activity
C9I28_RS12655	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C9I28_RS12685	COG1522	sequence-specific DNA binding
C9I28_RS12720	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C9I28_RS12725	COG0494	nUDIX hydrolase
C9I28_RS12765	COG1959	2 iron, 2 sulfur cluster binding
C9I28_RS12780	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C9I28_RS12810	COG1252	NADH dehydrogenase
C9I28_RS12830	COG3850	Histidine kinase
C9I28_RS12840	COG5002	protein histidine kinase activity
C9I28_RS12895	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C9I28_RS12915	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C9I28_RS12930	COG1496	oxidoreductase activity
C9I28_RS12940	COG0477	Major facilitator Superfamily
C9I28_RS12955	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
C9I28_RS12960	COG1028	Short-chain dehydrogenase reductase Sdr
C9I28_RS13000	COG0829	nickel cation binding
C9I28_RS13010	COG0832	Belongs to the urease beta subunit family
C9I28_RS13015	COG0804	urea catabolic process
C9I28_RS13020	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
C9I28_RS13025	COG0830	nickel cation binding
C9I28_RS13030	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
C9I28_RS13045	COG0484	heat shock protein binding
C9I28_RS13050	COG1902	pentaerythritol trinitrate reductase activity
C9I28_RS13060	COG2076	Multidrug Resistance protein
C9I28_RS13110	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
C9I28_RS13120	COG0688	phosphatidylethanolamine metabolic process
C9I28_RS13125	COG4771	TonB-dependent receptor
C9I28_RS13135	COG1228	amidohydrolase
C9I28_RS13150	COG0697	spore germination
C9I28_RS13185	COG1418	mRNA catabolic process
C9I28_RS13190	COG0835	chemotaxis
C9I28_RS13245	COG1262	PFAM Formylglycine-generating sulfatase enzyme
C9I28_RS13245	COG0515	serine threonine protein kinase
C9I28_RS13255	COG5652	VanZ like family
C9I28_RS13265	COG1741	Belongs to the pirin family
C9I28_RS13350	COG0038	chloride channel
C9I28_RS13370	COG4771	TonB-dependent receptor
C9I28_RS13375	COG1169	isochorismate synthase
C9I28_RS13380	COG1021	2,3-dihydroxybenzoate-AMP ligase
C9I28_RS13385	COG3433	isochorismatase activity
C9I28_RS13385	COG1535	isochorismatase
C9I28_RS13390	COG1028	Short-chain dehydrogenase reductase Sdr
C9I28_RS13395	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C9I28_RS13400	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C9I28_RS13420	COG2382	esterase
C9I28_RS13425	COG3251	PFAM MbtH domain protein
C9I28_RS13430	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C9I28_RS13460	COG4774	siderophore transport
C9I28_RS13485	COG0784	Response regulator, receiver
C9I28_RS13485	COG2205	protein histidine kinase activity
C9I28_RS13485	COG5002	protein histidine kinase activity
C9I28_RS13495	COG0189	ligase activity
C9I28_RS13495	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C9I28_RS13540	COG0640	Transcriptional regulator
C9I28_RS13550	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C9I28_RS13555	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C9I28_RS13560	COG0431	NADPH-dependent FMN reductase
C9I28_RS13590	COG1940	carbohydrate kinase activity
C9I28_RS13595	COG2382	esterase
C9I28_RS13595	COG3693	PFAM glycoside hydrolase, family 10
C9I28_RS13595	COG3507	Belongs to the glycosyl hydrolase 43 family
C9I28_RS13600	COG3591	Belongs to the peptidase S1B family
C9I28_RS13600	COG1864	DNA RNA non-specific endonuclease
C9I28_RS13620	COG4191	Histidine kinase
C9I28_RS13620	COG0784	Response regulator, receiver
C9I28_RS13635	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
C9I28_RS13645	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C9I28_RS13690	COG2165	general secretion pathway protein
C9I28_RS13700	COG1459	type II secretion system
C9I28_RS13775	COG0626	cystathionine gamma-synthase activity
C9I28_RS13780	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C9I28_RS13785	COG1435	thymidine kinase activity
C9I28_RS13800	COG2080	2 iron, 2 sulfur cluster binding
C9I28_RS13805	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
C9I28_RS13810	COG1529	Aldehyde oxidase and xanthine dehydrogenase
C9I28_RS13815	COG0656	L-ascorbic acid biosynthetic process
C9I28_RS13820	COG0753	catalase activity
C9I28_RS13890	COG3411	Ferredoxin
C9I28_RS13910	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
C9I28_RS13915	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
C9I28_RS13950	COG1960	acyl-CoA dehydrogenase activity
C9I28_RS14025	COG3267	Type II secretory pathway component ExeA
C9I28_RS14025	COG3409	Peptidoglycan-binding domain 1 protein
C9I28_RS14030	COG1131	(ABC) transporter
C9I28_RS14035	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C9I28_RS14040	COG1459	type II secretion system
C9I28_RS14050	COG2165	general secretion pathway protein
C9I28_RS14115	COG3409	Peptidoglycan-binding domain 1 protein
C9I28_RS14115	COG3267	Type II secretory pathway component ExeA
C9I28_RS14125	COG2199	diguanylate cyclase activity
C9I28_RS14125	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
C9I28_RS14130	COG0436	Aminotransferase
C9I28_RS14140	COG3022	response to hydroperoxide
C9I28_RS14150	COG0564	pseudouridine synthase activity
C9I28_RS14165	COG3243	poly(R)-hydroxyalkanoic acid synthase
C9I28_RS14170	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
C9I28_RS14185	COG1175	transmembrane transport
C9I28_RS14195	COG3842	ATPase activity
C9I28_RS14205	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C9I28_RS14210	COG0626	cystathionine gamma-synthase activity
C9I28_RS14235	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
C9I28_RS14240	COG1804	L-carnitine dehydratase bile acid-inducible protein F
C9I28_RS14250	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C9I28_RS14275	COG1611	Belongs to the LOG family
C9I28_RS14295	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
C9I28_RS14305	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
C9I28_RS14325	COG3739	integral membrane protein
C9I28_RS14375	COG4591	ABC-type transport system involved in lipoprotein release permease component
C9I28_RS14380	COG1136	(ABC) transporter
C9I28_RS14385	COG0084	hydrolase, TatD family'
C9I28_RS14395	COG2271	Major facilitator Superfamily
C9I28_RS14400	COG1609	Transcriptional regulator
C9I28_RS14425	COG2267	carboxylic ester hydrolase activity
C9I28_RS14430	COG0717	Belongs to the dCTP deaminase family
C9I28_RS14440	COG0745	RESPONSE REGULATOR receiver
C9I28_RS14525	COG0693	protein deglycase activity
C9I28_RS14535	COG0513	Belongs to the DEAD box helicase family
C9I28_RS14545	COG1132	(ABC) transporter
C9I28_RS14565	COG0277	FAD linked oxidase domain protein
C9I28_RS14580	COG1295	ribonuclease BN
C9I28_RS14600	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
C9I28_RS14610	COG3300	MHYT domain
C9I28_RS14610	COG5001	Diguanylate cyclase
C9I28_RS14620	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
C9I28_RS14630	COG1278	Cold shock
C9I28_RS14635	COG0583	DNA-binding transcription factor activity
C9I28_RS14640	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
C9I28_RS14650	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C9I28_RS14655	COG2226	methyltransferase
C9I28_RS14660	COG0328	RNA-DNA hybrid ribonuclease activity
C9I28_RS14685	COG1733	regulation of RNA biosynthetic process
C9I28_RS14690	COG2819	hydrolase of the alpha beta superfamily
C9I28_RS14725	COG4191	Histidine kinase
C9I28_RS14735	COG1301	dicarboxylic acid transport
C9I28_RS14820	COG0840	transmembrane signaling receptor activity
C9I28_RS14865	COG0318	PFAM AMP-dependent synthetase and ligase
C9I28_RS14890	COG2205	protein histidine kinase activity
C9I28_RS14905	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
C9I28_RS14910	COG0243	molybdopterin cofactor binding
C9I28_RS14925	COG1132	(ABC) transporter
C9I28_RS14930	COG0189	ligase activity
C9I28_RS14930	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C9I28_RS14935	COG1181	Belongs to the D-alanine--D-alanine ligase family
C9I28_RS14935	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C9I28_RS14950	COG0443	Heat shock 70 kDa protein
C9I28_RS14970	COG1505	serine-type exopeptidase activity
C9I28_RS14975	COG0640	Transcriptional regulator
C9I28_RS14995	COG4251	negative regulation of phosphorylation
C9I28_RS14995	COG5001	Diguanylate cyclase
C9I28_RS14995	COG2203	Gaf domain
C9I28_RS14995	COG3706	GGDEF domain
C9I28_RS15000	COG4585	Histidine kinase
C9I28_RS15005	COG0602	queuosine metabolic process
C9I28_RS15010	COG0720	synthase
C9I28_RS15035	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
C9I28_RS15050	COG0183	Belongs to the thiolase family
C9I28_RS15065	COG2130	NADP-dependent
C9I28_RS15070	COG2153	protein acetylation
C9I28_RS15075	COG0583	DNA-binding transcription factor activity
C9I28_RS15080	COG0604	alcohol dehydrogenase
C9I28_RS15110	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C9I28_RS15115	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
C9I28_RS15130	COG1247	-acetyltransferase
C9I28_RS15135	COG0084	hydrolase, TatD family'
C9I28_RS15145	COG2264	protein methyltransferase activity
C9I28_RS15155	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
C9I28_RS15160	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
C9I28_RS15180	COG4104	PAAR repeat-containing protein
C9I28_RS15185	COG4104	PAAR repeat-containing protein
C9I28_RS15190	COG0826	peptidase U32
C9I28_RS15215	COG0489	protein tyrosine kinase activity
C9I28_RS15275	COG2205	protein histidine kinase activity
C9I28_RS15280	COG0745	RESPONSE REGULATOR receiver
C9I28_RS15300	COG2308	Evidence 4 Homologs of previously reported genes of
C9I28_RS15305	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
C9I28_RS15315	COG1028	Short-chain dehydrogenase reductase Sdr
C9I28_RS15380	COG0741	lytic transglycosylase activity
C9I28_RS15380	COG1196	nuclear chromosome segregation
C9I28_RS15380	COG0739	heme binding
C9I28_RS15555	COG0438	transferase activity, transferring glycosyl groups
C9I28_RS15595	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C9I28_RS15600	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
C9I28_RS15615	COG0318	PFAM AMP-dependent synthetase and ligase
C9I28_RS15625	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C9I28_RS15630	COG2917	probably involved in intracellular septation
C9I28_RS15640	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C9I28_RS15645	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C9I28_RS15660	COG0583	DNA-binding transcription factor activity
C9I28_RS15665	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C9I28_RS15665	COG0047	phosphoribosylformylglycinamidine synthase activity
C9I28_RS15690	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
C9I28_RS15695	COG4181	ATPase activity
C9I28_RS15705	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
C9I28_RS15710	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C9I28_RS15720	COG0776	regulation of translation
C9I28_RS15730	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
C9I28_RS15735	COG0740	serine-type endopeptidase activity
C9I28_RS15740	COG0544	peptidyl-prolyl cis-trans isomerase activity
C9I28_RS15750	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C9I28_RS15760	COG1562	ergosterol biosynthetic process
C9I28_RS15765	COG1562	ergosterol biosynthetic process
C9I28_RS15770	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
C9I28_RS15790	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
C9I28_RS15795	COG0303	'Molybdopterin
C9I28_RS15805	COG1760	l-serine dehydratase
C9I28_RS15810	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C9I28_RS15815	COG0156	8-amino-7-oxononanoate synthase activity
C9I28_RS15880	COG2890	protein-(glutamine-N5) methyltransferase activity
C9I28_RS15885	COG1446	asparaginase
C9I28_RS15895	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C9I28_RS15895	COG1181	Belongs to the D-alanine--D-alanine ligase family
C9I28_RS15905	COG3706	GGDEF domain
C9I28_RS15915	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
C9I28_RS15920	COG2252	PERMEase
C9I28_RS15925	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
C9I28_RS15985	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C9I28_RS16015	COG1132	(ABC) transporter
C9I28_RS16040	COG1028	Short-chain dehydrogenase reductase Sdr
C9I28_RS16060	COG4771	TonB-dependent receptor
C9I28_RS16075	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C9I28_RS16090	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
C9I28_RS16105	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
C9I28_RS16110	COG1845	cytochrome c oxidase, subunit III
C9I28_RS16115	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C9I28_RS16120	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C9I28_RS16125	COG0477	Major facilitator Superfamily
C9I28_RS16130	COG5001	Diguanylate cyclase
C9I28_RS16140	COG0840	transmembrane signaling receptor activity
C9I28_RS16145	COG0840	transmembrane signaling receptor activity
C9I28_RS16160	COG1113	amino acid transport
C9I28_RS16165	COG2203	Gaf domain
C9I28_RS16165	COG3706	GGDEF domain
C9I28_RS16165	COG4251	negative regulation of phosphorylation
C9I28_RS16165	COG5001	Diguanylate cyclase
C9I28_RS16170	COG2205	protein histidine kinase activity
C9I28_RS16170	COG4999	Histidine kinase
C9I28_RS16170	COG3850	Histidine kinase
C9I28_RS16170	COG3437	response regulator, receiver
C9I28_RS16200	COG0531	amino acid
C9I28_RS16210	COG2197	response regulator
C9I28_RS16220	COG3916	Acyl-homoserine-lactone synthase
C9I28_RS16255	COG2197	response regulator
C9I28_RS16260	COG3850	Histidine kinase
C9I28_RS16270	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C9I28_RS16275	COG2181	nitrate reductase activity
C9I28_RS16280	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
C9I28_RS16285	COG1140	nitrate reductase beta subunit
C9I28_RS16290	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
C9I28_RS16340	COG0456	acetyltransferase
C9I28_RS16350	COG1349	DNA-binding transcription factor activity
C9I28_RS16365	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C9I28_RS16370	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C9I28_RS16375	COG2223	nitrite transmembrane transporter activity
C9I28_RS16385	COG1959	2 iron, 2 sulfur cluster binding
C9I28_RS16440	COG3154	lipid carrier protein
C9I28_RS16445	COG0826	peptidase U32
C9I28_RS16450	COG0826	peptidase U32
C9I28_RS16480	COG5652	VanZ like family
C9I28_RS16505	COG0395	ABC-type sugar transport system, permease component
C9I28_RS16510	COG1175	transmembrane transport
C9I28_RS16525	COG3507	Belongs to the glycosyl hydrolase 43 family
C9I28_RS16530	COG1472	Belongs to the glycosyl hydrolase 3 family
C9I28_RS16555	COG0668	transmembrane transport
C9I28_RS16565	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
C9I28_RS16570	COG2205	protein histidine kinase activity
C9I28_RS16570	COG0784	Response regulator, receiver
C9I28_RS16580	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C9I28_RS16590	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
C9I28_RS16640	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
C9I28_RS16645	COG1085	galactose-1-phosphate uridylyltransferase
C9I28_RS16665	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
C9I28_RS16665	COG2755	lipolytic protein G-D-S-L family
C9I28_RS16680	COG0110	maltose O-acetyltransferase activity
C9I28_RS16685	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C9I28_RS16710	COG1201	RNA secondary structure unwinding
C9I28_RS16715	COG3300	MHYT domain
C9I28_RS16715	COG5001	Diguanylate cyclase
C9I28_RS16885	COG2755	lipolytic protein G-D-S-L family
C9I28_RS16885	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
C9I28_RS16900	COG0596	Alpha beta hydrolase
C9I28_RS16985	COG2814	Major facilitator Superfamily
C9I28_RS16990	COG4264	IucA IucC family
C9I28_RS16995	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
C9I28_RS17000	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C9I28_RS17005	COG0019	diaminopimelate decarboxylase activity
C9I28_RS17050	COG4104	PAAR repeat-containing protein
C9I28_RS17080	COG4104	PAAR repeat-containing protein
C9I28_RS17095	COG0546	phosphoglycolate phosphatase activity
C9I28_RS17095	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
C9I28_RS17110	COG4221	oxidoreductase activity
C9I28_RS17140	COG0023	Translation Initiation Factor
C9I28_RS17155	COG0583	DNA-binding transcription factor activity
C9I28_RS17170	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
C9I28_RS17175	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C9I28_RS17235	COG0518	GMP synthase (glutamine-hydrolyzing) activity
C9I28_RS17235	COG0519	Catalyzes the synthesis of GMP from XMP
C9I28_RS17240	COG0517	IMP dehydrogenase activity
C9I28_RS17240	COG0516	GMP reductase activity
C9I28_RS17260	COG2914	Belongs to the UPF0125 (RnfH) family
C9I28_RS17265	COG2867	negative regulation of translational initiation
C9I28_RS17295	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
C9I28_RS17325	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
C9I28_RS17345	COG1028	Short-chain dehydrogenase reductase Sdr
C9I28_RS17350	COG1595	DNA-templated transcription, initiation
C9I28_RS17355	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C9I28_RS17365	COG2200	EAL domain
C9I28_RS17365	COG2199	diguanylate cyclase activity
C9I28_RS17365	COG2202	Pas domain
C9I28_RS17370	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C9I28_RS17375	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
C9I28_RS17380	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C9I28_RS17385	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C9I28_RS17390	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C9I28_RS17395	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C9I28_RS17410	COG0750	zinc metalloprotease
C9I28_RS17415	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
C9I28_RS17425	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C9I28_RS17430	COG0233	cytoplasmic translational termination
C9I28_RS17435	COG0528	UMP kinase activity
C9I28_RS17440	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
C9I28_RS17445	COG0052	Belongs to the universal ribosomal protein uS2 family
C9I28_RS17485	COG0024	Methionine aminopeptidase
C9I28_RS17490	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
C9I28_RS17495	COG1187	pseudouridine synthase activity
C9I28_RS17515	COG0642	Histidine kinase
C9I28_RS17520	COG0745	RESPONSE REGULATOR receiver
C9I28_RS17530	COG1297	OPT oligopeptide transporter protein
C9I28_RS17535	COG0242	peptide deformylase activity
C9I28_RS17540	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C9I28_RS17545	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
C9I28_RS17590	COG0404	The glycine cleavage system catalyzes the degradation of glycine
C9I28_RS17595	COG0509	glycine decarboxylation via glycine cleavage system
C9I28_RS17615	COG4249	Peptidase C14 caspase catalytic subunit p20
C9I28_RS17615	COG2319	Wd-40 repeat
C9I28_RS17650	COG1131	(ABC) transporter
C9I28_RS17655	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C9I28_RS17660	COG1819	glycosyl
C9I28_RS17665	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
C9I28_RS17695	COG4969	Belongs to the N-Me-Phe pilin family
C9I28_RS17705	COG0642	Histidine kinase
C9I28_RS17720	COG4585	Histidine kinase
C9I28_RS17725	COG2197	response regulator
C9I28_RS17735	COG0776	regulation of translation
C9I28_RS17740	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C9I28_RS17740	COG0072	phenylalanine-tRNA ligase activity
C9I28_RS17745	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
C9I28_RS17750	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
C9I28_RS17755	COG0291	Belongs to the bacterial ribosomal protein bL35 family
C9I28_RS17760	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
C9I28_RS17765	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
C9I28_RS17785	COG1230	cation diffusion facilitator family transporter
C9I28_RS17810	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C9I28_RS17815	COG0251	oxidation-reduction process
C9I28_RS17825	COG1028	Short-chain dehydrogenase reductase Sdr
C9I28_RS17830	COG4771	TonB-dependent receptor
C9I28_RS17845	COG1301	dicarboxylic acid transport
C9I28_RS17850	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C9I28_RS17870	COG4566	intracellular signal transduction
C9I28_RS17875	COG0840	transmembrane signaling receptor activity
C9I28_RS17885	COG0251	oxidation-reduction process
C9I28_RS17910	COG1028	Short-chain dehydrogenase reductase Sdr
C9I28_RS17920	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C9I28_RS17935	COG1262	PFAM Formylglycine-generating sulfatase enzyme
C9I28_RS17990	COG1987	bacterial-type flagellum assembly
C9I28_RS18000	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C9I28_RS18010	COG1677	Flagellar hook-basal body complex protein FliE
C9I28_RS18020	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C9I28_RS18070	COG1191	sigma factor activity
C9I28_RS18075	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C9I28_RS18095	COG3951	Flagellar rod assembly protein muramidase FlgJ
C9I28_RS18095	COG1705	Flagellar rod assembly protein muramidase FlgJ
C9I28_RS18125	COG1815	bacterial-type flagellum-dependent cell motility
C9I28_RS18140	COG1749	Flagellar hook protein flgE
C9I28_RS18150	COG4786	Flagellar basal body rod
C9I28_RS18175	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C9I28_RS18185	COG5001	Diguanylate cyclase
C9I28_RS18225	COG2319	Wd-40 repeat
C9I28_RS18225	COG4249	Peptidase C14 caspase catalytic subunit p20
C9I28_RS18240	COG0772	Belongs to the SEDS family
C9I28_RS18250	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
C9I28_RS18280	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C9I28_RS18285	COG1074	ATP-dependent DNA helicase activity
C9I28_RS18290	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
C9I28_RS18340	COG0708	Exodeoxyribonuclease III
C9I28_RS18350	COG1505	serine-type exopeptidase activity
C9I28_RS18360	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
C9I28_RS18365	COG0625	glutathione transferase activity
C9I28_RS18370	COG0840	transmembrane signaling receptor activity
C9I28_RS18380	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
C9I28_RS18385	COG0784	Response regulator, receiver
C9I28_RS18385	COG3437	response regulator, receiver
C9I28_RS18400	COG2059	Chromate
C9I28_RS18410	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
C9I28_RS18415	COG2353	YceI-like domain
C9I28_RS18425	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C9I28_RS18435	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C9I28_RS18440	COG0431	NADPH-dependent FMN reductase
C9I28_RS18450	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C9I28_RS18455	COG2011	ABC-type metal ion transport system permease component
C9I28_RS18460	COG1464	Belongs to the NlpA lipoprotein family
C9I28_RS18475	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C9I28_RS18485	COG1045	serine acetyltransferase
C9I28_RS18490	COG2814	Major facilitator Superfamily
C9I28_RS18540	COG4662	Binding-protein-dependent transport system inner membrane component
C9I28_RS18550	COG3383	formate dehydrogenase (NAD+) activity
C9I28_RS18560	COG1910	domain protein
C9I28_RS18575	COG2135	peptidase activity
C9I28_RS18590	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C9I28_RS18600	COG4191	Histidine kinase
C9I28_RS18600	COG0784	Response regulator, receiver
C9I28_RS18620	COG3546	catalase activity
C9I28_RS18630	COG1960	acyl-CoA dehydrogenase activity
C9I28_RS18635	COG0318	PFAM AMP-dependent synthetase and ligase
C9I28_RS18755	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
C9I28_RS18780	COG0835	chemotaxis
C9I28_RS18780	COG0784	Response regulator, receiver
C9I28_RS18800	COG0025	NhaP-type Na H and K H
C9I28_RS18805	COG3275	phosphorelay sensor kinase activity
C9I28_RS18810	COG3279	Response regulator of the LytR AlgR family
C9I28_RS18825	COG3706	GGDEF domain
C9I28_RS18845	COG0625	glutathione transferase activity
C9I28_RS18855	COG2205	protein histidine kinase activity
C9I28_RS18880	COG1172	Belongs to the binding-protein-dependent transport system permease family
C9I28_RS18885	COG1172	Belongs to the binding-protein-dependent transport system permease family
C9I28_RS18890	COG1129	ABC transporter
C9I28_RS18895	COG1879	ABC-type sugar transport system periplasmic component
C9I28_RS18905	COG3507	Belongs to the glycosyl hydrolase 43 family
C9I28_RS18910	COG3507	Belongs to the glycosyl hydrolase 43 family
C9I28_RS18920	COG1082	Xylose isomerase domain protein TIM barrel
C9I28_RS18945	COG3940	Belongs to the glycosyl hydrolase 43 family
C9I28_RS18955	COG3940	Belongs to the glycosyl hydrolase 43 family
C9I28_RS18960	COG2211	Major facilitator Superfamily
C9I28_RS19005	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C9I28_RS19010	COG0534	Mate efflux family protein
C9I28_RS19040	COG4774	siderophore transport
C9I28_RS19045	COG4771	TonB-dependent receptor
C9I28_RS19060	COG2205	protein histidine kinase activity
C9I28_RS19060	COG5002	protein histidine kinase activity
C9I28_RS19060	COG0784	Response regulator, receiver
C9I28_RS19070	COG0417	DNA replication proofreading
C9I28_RS19075	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C9I28_RS19090	COG0662	Cupin 2, conserved barrel domain protein
C9I28_RS19130	COG1472	Belongs to the glycosyl hydrolase 3 family
C9I28_RS19140	COG1874	Beta-galactosidase
C9I28_RS19165	COG4213	ABC transporter substrate-binding protein
C9I28_RS19175	COG1609	Transcriptional regulator
C9I28_RS19175	COG2207	Transcriptional regulator
C9I28_RS19180	COG2252	PERMEase
C9I28_RS19185	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C9I28_RS19185	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C9I28_RS19200	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C9I28_RS19205	COG1262	PFAM Formylglycine-generating sulfatase enzyme
C9I28_RS19225	COG0318	PFAM AMP-dependent synthetase and ligase
C9I28_RS19230	COG4585	Histidine kinase
C9I28_RS19235	COG2197	response regulator
C9I28_RS19255	COG1869	D-ribose catabolic process
C9I28_RS19260	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C9I28_RS19265	COG1609	Transcriptional regulator
C9I28_RS19270	COG1172	Belongs to the binding-protein-dependent transport system permease family
C9I28_RS19275	COG1129	ABC transporter
C9I28_RS19280	COG1879	ABC-type sugar transport system periplasmic component
C9I28_RS19295	COG2897	thiosulfate sulfurtransferase activity
C9I28_RS19330	COG0322	excinuclease ABC activity
C9I28_RS19335	COG0736	holo-[acyl-carrier-protein] synthase activity
C9I28_RS19350	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
C9I28_RS19355	COG0571	ribonuclease III activity
C9I28_RS19370	COG0481	GTPase activity
C9I28_RS19380	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C9I28_RS19405	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C9I28_RS19420	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C9I28_RS19425	COG0416	fatty acid biosynthetic process
C9I28_RS19430	COG0333	Belongs to the bacterial ribosomal protein bL32 family
C9I28_RS19445	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
C9I28_RS19450	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
C9I28_RS19455	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
C9I28_RS19460	COG2224	Isocitrate lyase
C9I28_RS19465	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
C9I28_RS19515	COG0542	response to heat
C9I28_RS19525	COG0314	molybdopterin synthase activity
C9I28_RS19540	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C9I28_RS19540	COG0045	succinate-CoA ligase (ADP-forming) activity
C9I28_RS19540	COG1042	CoA-binding domain protein
C9I28_RS19550	COG3214	Protein conserved in bacteria
C9I28_RS19565	COG0420	3'-5' exonuclease activity
C9I28_RS19605	COG0513	Belongs to the DEAD box helicase family
C9I28_RS19610	COG0154	amidase activity
C9I28_RS19615	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
C9I28_RS19640	COG1845	cytochrome c oxidase, subunit III
C9I28_RS19650	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C9I28_RS19655	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C9I28_RS19695	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C9I28_RS19715	COG0489	protein tyrosine kinase activity
C9I28_RS19720	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C9I28_RS19720	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C9I28_RS19730	COG0697	spore germination
C9I28_RS19740	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
C9I28_RS19745	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
C9I28_RS19750	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
C9I28_RS19760	COG0745	RESPONSE REGULATOR receiver
C9I28_RS19765	COG2201	protein-glutamate methylesterase activity
C9I28_RS19770	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
C9I28_RS19775	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
C9I28_RS19780	COG0840	transmembrane signaling receptor activity
C9I28_RS19785	COG0835	chemotaxis
C9I28_RS19790	COG0643	Histidine kinase
C9I28_RS19790	COG2198	Histidine kinase
C9I28_RS19795	COG0745	RESPONSE REGULATOR receiver
C9I28_RS19805	COG1360	Flagellar Motor Protein
C9I28_RS19815	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
C9I28_RS19835	COG3483	tryptophan 2,3-dioxygenase activity
C9I28_RS19845	COG4251	negative regulation of phosphorylation
C9I28_RS19850	COG0784	Response regulator, receiver
C9I28_RS19915	COG0697	spore germination
C9I28_RS19920	COG0251	oxidation-reduction process
C9I28_RS19925	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C9I28_RS19935	COG1070	Carbohydrate kinase
C9I28_RS19940	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
C9I28_RS19945	COG0277	FAD linked oxidase domain protein
C9I28_RS19970	COG0612	Peptidase, M16
C9I28_RS19980	COG0477	Major facilitator Superfamily
C9I28_RS20020	COG0513	Belongs to the DEAD box helicase family
C9I28_RS20030	COG1309	transcriptional regulator
C9I28_RS20035	COG4948	Mandelate Racemase Muconate Lactonizing
C9I28_RS20080	COG1280	lysine exporter protein (LysE YggA)
C9I28_RS20090	COG0436	Aminotransferase
C9I28_RS20095	COG2171	N-acyltransferase activity
C9I28_RS20105	COG1393	Belongs to the ArsC family
C9I28_RS20110	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C9I28_RS20115	COG2890	protein-(glutamine-N5) methyltransferase activity
C9I28_RS20120	COG0488	(ABC) transporter
C9I28_RS20125	COG0835	chemotaxis
C9I28_RS20130	COG1804	L-carnitine dehydratase bile acid-inducible protein F
C9I28_RS20165	COG3795	YCII-related domain
C9I28_RS20170	COG4941	Belongs to the sigma-70 factor family
C9I28_RS20190	COG4771	TonB-dependent receptor
C9I28_RS20210	COG2205	protein histidine kinase activity
C9I28_RS20215	COG4990	cell redox homeostasis
C9I28_RS20215	COG3591	Belongs to the peptidase S1B family
C9I28_RS20235	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C9I28_RS20250	COG5002	protein histidine kinase activity
C9I28_RS20255	COG1278	Cold shock
C9I28_RS20300	COG2972	Histidine kinase
C9I28_RS20325	COG0616	signal peptide processing
C9I28_RS20330	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C9I28_RS20335	COG0232	Belongs to the dGTPase family. Type 2 subfamily
C9I28_RS20355	COG3530	Putative quorum-sensing-regulated virulence factor
C9I28_RS20360	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
C9I28_RS20370	COG0625	glutathione transferase activity
C9I28_RS20380	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
C9I28_RS20385	COG0583	DNA-binding transcription factor activity
C9I28_RS20395	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C9I28_RS20430	COG0475	glutathione-regulated potassium exporter activity
C9I28_RS20460	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
C9I28_RS20465	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
C9I28_RS20485	COG1007	ATP synthesis coupled electron transport
C9I28_RS20500	COG0713	ATP synthesis coupled electron transport
C9I28_RS20510	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C9I28_RS20515	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
C9I28_RS20530	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
C9I28_RS20535	COG0649	NAD binding
C9I28_RS20540	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C9I28_RS20545	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C9I28_RS20550	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C9I28_RS20565	COG0149	triose-phosphate isomerase activity
C9I28_RS20610	COG4771	TonB-dependent receptor
C9I28_RS20635	COG2755	lipolytic protein G-D-S-L family
C9I28_RS20645	COG3345	alpha-galactosidase
C9I28_RS20655	COG1472	Belongs to the glycosyl hydrolase 3 family
C9I28_RS20665	COG1609	Transcriptional regulator
C9I28_RS20715	COG1185	polyribonucleotide nucleotidyltransferase activity
C9I28_RS20720	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
C9I28_RS20730	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C9I28_RS20735	COG1183	phosphatidylcholine synthase activity
C9I28_RS20750	COG4191	Histidine kinase
C9I28_RS20750	COG0784	Response regulator, receiver
C9I28_RS20760	COG3275	phosphorelay sensor kinase activity
C9I28_RS20770	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
C9I28_RS20775	COG0440	acetolactate synthase activity
C9I28_RS20780	COG0028	Belongs to the TPP enzyme family
C9I28_RS20820	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
C9I28_RS20830	COG2975	iron-sulfur cluster assembly
C9I28_RS20840	COG0443	Heat shock 70 kDa protein
C9I28_RS20845	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
C9I28_RS20850	COG0316	Belongs to the HesB IscA family
C9I28_RS20855	COG0822	iron-sulfur transferase activity
C9I28_RS20860	COG1104	cysteine desulfurase activity
C9I28_RS20880	COG0625	glutathione transferase activity
C9I28_RS20890	COG4580	involved in the transport of maltose and maltodextrins
C9I28_RS20915	COG4154	Belongs to the RbsD FucU family
C9I28_RS20930	COG0583	DNA-binding transcription factor activity
C9I28_RS20950	COG0443	Heat shock 70 kDa protein
C9I28_RS20965	COG0840	transmembrane signaling receptor activity
C9I28_RS21025	COG0693	protein deglycase activity
C9I28_RS21050	COG3275	phosphorelay sensor kinase activity
C9I28_RS21075	COG2610	gluconate transmembrane transporter activity
C9I28_RS21125	COG0556	nucleotide-excision repair
C9I28_RS21135	COG1917	Cupin 2, conserved barrel domain protein
C9I28_RS21150	COG2095	MarC family integral membrane protein
C9I28_RS21160	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
C9I28_RS21165	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
C9I28_RS21170	COG0330	HflC and HflK could
C9I28_RS21175	COG0330	HflC and HflK could
C9I28_RS21180	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C9I28_RS21185	COG1923	regulation of RNA biosynthetic process
C9I28_RS21190	COG1160	GTP binding
C9I28_RS21205	COG0124	histidyl-tRNA synthetase
C9I28_RS21210	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
C9I28_RS21225	COG0820	rRNA (adenine-C2-)-methyltransferase activity
C9I28_RS21230	COG0105	UTP biosynthetic process
C9I28_RS21250	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C9I28_RS21260	COG1388	LysM domain
C9I28_RS21260	COG4942	peptidase
C9I28_RS21265	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
C9I28_RS21270	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
C9I28_RS21285	COG1199	ATP-dependent helicase activity
C9I28_RS21315	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
C9I28_RS21320	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C9I28_RS21330	COG0508	dehydrogenase complex catalyzes the overall conversion of
C9I28_RS21335	COG0567	Dehydrogenase, E1 component
C9I28_RS21355	COG5002	protein histidine kinase activity
C9I28_RS21360	COG2205	protein histidine kinase activity
C9I28_RS21360	COG2202	Pas domain
C9I28_RS21370	COG5002	protein histidine kinase activity
C9I28_RS21375	COG2205	protein histidine kinase activity
C9I28_RS21385	COG5002	protein histidine kinase activity
C9I28_RS21390	COG0372	Belongs to the citrate synthase family
C9I28_RS21395	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
C9I28_RS21400	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C9I28_RS21405	COG1053	succinate dehydrogenase
C9I28_RS21410	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
C9I28_RS21415	COG2009	succinate dehydrogenase
C9I28_RS21420	COG2188	Transcriptional regulator
C9I28_RS21440	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
C9I28_RS21450	COG2801	Transposase and inactivated derivatives
C9I28_RS21450	COG3415	Transposase
C9I28_RS21465	COG2954	triphosphatase activity
C9I28_RS21470	COG2866	Carboxypeptidase
C9I28_RS21475	COG0753	catalase activity
C9I28_RS21485	COG0427	acetyl-CoA hydrolase
C9I28_RS21490	COG0583	DNA-binding transcription factor activity
C9I28_RS21555	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C9I28_RS21560	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C9I28_RS21570	COG0477	Major facilitator Superfamily
C9I28_RS21575	COG3851	Histidine kinase
C9I28_RS21600	COG2205	protein histidine kinase activity
C9I28_RS21610	COG2204	response regulator
C9I28_RS21640	COG0436	Aminotransferase
C9I28_RS21650	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C9I28_RS21655	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
C9I28_RS21660	COG2608	mercury ion transmembrane transporter activity
C9I28_RS21680	COG0789	Transcriptional regulator
C9I28_RS21685	COG2217	Heavy metal translocating P-type atpase
C9I28_RS21715	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
C9I28_RS21745	COG1396	sequence-specific DNA binding
C9I28_RS21755	COG0306	phosphate transporter
C9I28_RS21765	COG0305	Participates in initiation and elongation during chromosome replication
C9I28_RS21770	COG0359	binds to the 23S rRNA
C9I28_RS21775	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
C9I28_RS21785	COG0360	Binds together with S18 to 16S ribosomal RNA
C9I28_RS21790	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C9I28_RS21805	COG1286	toxin biosynthetic process
C9I28_RS21815	COG0285	dihydrofolate synthase activity
C9I28_RS21820	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
C9I28_RS21825	COG0159	tryptophan synthase activity
C9I28_RS21830	COG0133	tryptophan synthase activity
C9I28_RS21835	COG0135	phosphoribosylanthranilate isomerase activity
C9I28_RS21840	COG0101	tRNA pseudouridine synthase activity
C9I28_RS21850	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C9I28_RS21855	COG0473	3-isopropylmalate dehydrogenase activity
C9I28_RS21860	COG0066	3-isopropylmalate dehydratase activity
C9I28_RS21870	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
C9I28_RS21875	COG0643	Histidine kinase
C9I28_RS21875	COG2198	Histidine kinase
C9I28_RS21875	COG0784	Response regulator, receiver
C9I28_RS21880	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
C9I28_RS21895	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C9I28_RS21915	COG4206	TonB-dependent receptor
C9I28_RS21925	COG1477	protein flavinylation
C9I28_RS21965	COG1201	RNA secondary structure unwinding
C9I28_RS21970	COG1793	dna ligase
C9I28_RS21975	COG1793	dna ligase
C9I28_RS21975	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
C9I28_RS21980	COG0514	ATP-dependent DNA helicase (RecQ)
C9I28_RS21990	COG4191	Histidine kinase
C9I28_RS21990	COG0784	Response regulator, receiver
C9I28_RS22010	COG1956	GAF domain-containing protein
C9I28_RS22040	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
C9I28_RS22055	COG2850	peptidyl-arginine hydroxylation
C9I28_RS22070	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C9I28_RS22090	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C9I28_RS22110	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
C9I28_RS22115	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C9I28_RS22125	COG0180	Tryptophanyl-tRNA synthetase
C9I28_RS22130	COG1994	Peptidase M50
C9I28_RS22135	COG0009	L-threonylcarbamoyladenylate synthase
C9I28_RS22140	COG0501	Belongs to the peptidase M48B family
C9I28_RS22150	COG0613	PHP domain protein
C9I28_RS22155	COG0596	Alpha beta hydrolase
C9I28_RS22165	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
C9I28_RS22180	COG1022	Amp-dependent synthetase and ligase
C9I28_RS22195	COG0584	glycerophosphoryl diester phosphodiesterase
C9I28_RS22215	COG0004	ammonium transporteR
C9I28_RS22220	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
C9I28_RS22225	COG0148	phosphopyruvate hydratase activity
C9I28_RS22235	COG2877	3-deoxy-8-phosphooctulonate synthase activity
C9I28_RS22240	COG0504	CTP synthase activity
C9I28_RS22290	COG0737	Belongs to the 5'-nucleotidase family
C9I28_RS22300	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
C9I28_RS22305	COG0642	Histidine kinase
C9I28_RS22315	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C9I28_RS22370	COG1643	Atp-dependent helicase
C9I28_RS22375	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
C9I28_RS22375	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
C9I28_RS22380	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
C9I28_RS22385	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
C9I28_RS22395	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
C9I28_RS22410	COG5001	Diguanylate cyclase
C9I28_RS22410	COG4251	negative regulation of phosphorylation
C9I28_RS22410	COG3706	GGDEF domain
C9I28_RS22410	COG2203	Gaf domain
C9I28_RS22420	COG2201	protein-glutamate methylesterase activity
C9I28_RS22430	COG0835	chemotaxis
C9I28_RS22445	COG0643	Histidine kinase
C9I28_RS22445	COG2198	Histidine kinase
C9I28_RS22455	COG0745	RESPONSE REGULATOR receiver
C9I28_RS22460	COG0840	transmembrane signaling receptor activity
C9I28_RS22485	COG0800	Aldolase
C9I28_RS22495	COG0166	Belongs to the GPI family
C9I28_RS22505	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
C9I28_RS22510	COG1737	Transcriptional regulator
C9I28_RS22515	COG1794	racemase activity, acting on amino acids and derivatives
C9I28_RS22525	COG3842	ATPase activity
C9I28_RS22535	COG1840	ABC-type Fe3 transport system, periplasmic component
C9I28_RS22575	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C9I28_RS22580	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C9I28_RS22585	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C9I28_RS22600	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C9I28_RS22605	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
C9I28_RS22625	COG1561	YicC-like family, N-terminal region
C9I28_RS22635	COG0194	GDP metabolic process
C9I28_RS22640	COG1758	RNA polymerase activity
C9I28_RS22645	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C9I28_RS22660	COG3851	Histidine kinase
C9I28_RS22705	COG2257	FlhB HrpN YscU SpaS Family
C9I28_RS22710	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
C9I28_RS22715	COG1677	Flagellar hook-basal body complex protein FliE
C9I28_RS22720	COG1766	The M ring may be actively involved in energy transduction
C9I28_RS22725	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C9I28_RS22740	COG2882	bacterial-type flagellum organization
C9I28_RS22750	COG1580	Controls the rotational direction of flagella during chemotaxis
C9I28_RS22760	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C9I28_RS22765	COG3190	flagellar
C9I28_RS22780	COG1684	flagellar biosynthetic protein fliR
C9I28_RS22795	COG1705	Flagellar rod assembly protein muramidase FlgJ
C9I28_RS22795	COG3951	Flagellar rod assembly protein muramidase FlgJ
C9I28_RS22800	COG1706	bacterial-type flagellum-dependent cell motility
C9I28_RS22805	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
C9I28_RS22815	COG4787	bacterial-type flagellum-dependent cell motility
C9I28_RS22830	COG1558	bacterial-type flagellum-dependent cell motility
C9I28_RS22835	COG1815	bacterial-type flagellum-dependent cell motility
C9I28_RS22895	COG3209	COG3209 Rhs family protein
C9I28_RS22915	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C9I28_RS22955	COG1187	pseudouridine synthase activity
C9I28_RS22975	COG0546	phosphoglycolate phosphatase activity
C9I28_RS22985	COG1530	ribonuclease E activity
C9I28_RS22995	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
C9I28_RS23000	COG0303	'Molybdopterin
C9I28_RS23015	COG5002	protein histidine kinase activity
C9I28_RS23025	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
C9I28_RS23030	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
C9I28_RS23035	COG2766	serine protein kinase
C9I28_RS23040	COG2718	Belongs to the UPF0229 family
C9I28_RS23045	COG2719	SpoVR family
C9I28_RS23075	COG0196	riboflavin kinase activity
C9I28_RS23085	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
C9I28_RS23090	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C9I28_RS23095	COG0756	dUTP diphosphatase activity
C9I28_RS23120	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
C9I28_RS23125	COG0789	Transcriptional regulator
C9I28_RS23145	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
C9I28_RS23150	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
C9I28_RS23155	COG0167	dihydroorotate dehydrogenase activity
C9I28_RS23160	COG0667	Aldo Keto reductase
C9I28_RS23185	COG0583	DNA-binding transcription factor activity
C9I28_RS23190	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
C9I28_RS23195	COG4208	sulfate ABC transporter
C9I28_RS23205	COG0450	alkyl hydroperoxide reductase
C9I28_RS23215	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
C9I28_RS23280	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
C9I28_RS23285	COG1047	Peptidyl-prolyl cis-trans
C9I28_RS23290	COG2003	Belongs to the UPF0758 family
C9I28_RS23295	COG1368	sulfuric ester hydrolase activity
C9I28_RS23300	COG0227	Belongs to the bacterial ribosomal protein bL28 family
C9I28_RS23305	COG0267	Belongs to the bacterial ribosomal protein bL33 family
C9I28_RS23320	COG3264	Mechanosensitive ion channel
C9I28_RS23320	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
C9I28_RS23325	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C9I28_RS23325	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C9I28_RS23330	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C9I28_RS23345	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
C9I28_RS23350	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C9I28_RS23400	COG0384	phenazine biosynthesis protein PhzF
C9I28_RS23410	COG2823	Periplasmic or secreted lipoprotein
C9I28_RS23420	COG0840	transmembrane signaling receptor activity
C9I28_RS23435	COG3845	ABC transporter
C9I28_RS23445	COG0583	DNA-binding transcription factor activity
C9I28_RS23450	COG0778	Nitroreductase
C9I28_RS23455	COG0583	DNA-binding transcription factor activity
C9I28_RS23485	COG2723	6-phospho-beta-galactosidase activity
C9I28_RS23500	COG4771	TonB-dependent receptor
C9I28_RS23510	COG1609	Transcriptional regulator
C9I28_RS23525	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C9I28_RS23530	COG0508	dehydrogenase complex catalyzes the overall conversion of
C9I28_RS23535	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
C9I28_RS23540	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
C9I28_RS23570	COG4654	Cytochrome c, class I
C9I28_RS23585	COG0129	dihydroxy-acid dehydratase activity
C9I28_RS23590	COG0583	DNA-binding transcription factor activity
C9I28_RS23595	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
C9I28_RS23620	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
C9I28_RS23630	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
C9I28_RS23635	COG0459	protein refolding
C9I28_RS23640	COG0028	Belongs to the TPP enzyme family
C9I28_RS23655	COG2814	Major facilitator Superfamily
C9I28_RS23665	COG0837	glucose binding
C9I28_RS23665	COG1737	Transcriptional regulator
C9I28_RS23670	COG0366	Alpha amylase catalytic
C9I28_RS23680	COG0840	transmembrane signaling receptor activity
C9I28_RS23695	COG0366	Alpha amylase catalytic
C9I28_RS23700	COG0033	Phosphoglucomutase
C9I28_RS23710	COG1501	Belongs to the glycosyl hydrolase 31 family
C9I28_RS23740	COG0366	Alpha amylase catalytic
C9I28_RS23755	COG0402	S-adenosylhomocysteine deaminase activity
C9I28_RS23765	COG1132	(ABC) transporter
C9I28_RS23770	COG1132	(ABC) transporter
C9I28_RS23825	COG0583	DNA-binding transcription factor activity
C9I28_RS23830	COG5285	phytanoyl-CoA dioxygenase
C9I28_RS23850	COG1846	Transcriptional regulator
C9I28_RS23875	COG3437	response regulator, receiver
C9I28_RS23875	COG2205	protein histidine kinase activity
C9I28_RS23875	COG4999	Histidine kinase
C9I28_RS23875	COG3850	Histidine kinase
C9I28_RS23905	COG0655	NAD(P)H dehydrogenase (quinone) activity
C9I28_RS23920	COG0840	transmembrane signaling receptor activity
C9I28_RS23935	COG1538	Outer membrane efflux protein
C9I28_RS23975	COG0667	Aldo Keto reductase
C9I28_RS23995	COG4221	oxidoreductase activity
C9I28_RS24025	COG3275	phosphorelay sensor kinase activity
C9I28_RS24040	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
C9I28_RS24045	COG0308	aminopeptidase N
C9I28_RS24065	COG1803	Methylglyoxal synthase
C9I28_RS24085	COG0217	transcriptional regulatory protein
C9I28_RS24090	COG0151	Belongs to the GarS family
C9I28_RS24095	COG0408	coproporphyrinogen oxidase activity
C9I28_RS24105	COG0799	negative regulation of ribosome biogenesis
C9I28_RS24110	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
C9I28_RS24115	COG0424	maF-like protein
C9I28_RS24120	COG1530	ribonuclease E activity
C9I28_RS24165	COG1696	Membrane protein involved in D-alanine export
C9I28_RS24180	COG1054	Belongs to the UPF0176 family
C9I28_RS24205	COG0500	methyltransferase
C9I28_RS24210	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
C9I28_RS24235	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C9I28_RS24250	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C9I28_RS24255	COG0438	transferase activity, transferring glycosyl groups
C9I28_RS24290	COG0513	Belongs to the DEAD box helicase family
C9I28_RS24295	COG2203	Gaf domain
C9I28_RS24295	COG3706	GGDEF domain
C9I28_RS24295	COG5001	Diguanylate cyclase
C9I28_RS24295	COG4251	negative regulation of phosphorylation
C9I28_RS24310	COG0840	transmembrane signaling receptor activity
C9I28_RS24330	COG2080	2 iron, 2 sulfur cluster binding
C9I28_RS24335	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
C9I28_RS24340	COG1529	Aldehyde oxidase and xanthine dehydrogenase
C9I28_RS24360	COG1529	Aldehyde oxidase and xanthine dehydrogenase
C9I28_RS24365	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
C9I28_RS24370	COG2080	2 iron, 2 sulfur cluster binding
C9I28_RS24375	COG2832	Protein of unknown function (DUF454)
C9I28_RS24405	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
C9I28_RS24410	COG0318	PFAM AMP-dependent synthetase and ligase
C9I28_RS24425	COG1414	Transcriptional regulator
C9I28_RS24440	COG0559	Belongs to the binding-protein-dependent transport system permease family
C9I28_RS24470	COG1960	acyl-CoA dehydrogenase activity
C9I28_RS24475	COG1960	acyl-CoA dehydrogenase activity
C9I28_RS24480	COG0183	Belongs to the thiolase family
C9I28_RS24485	COG1250	3-hydroxyacyl-CoA dehydrogenase
C9I28_RS24485	COG1024	Enoyl-CoA hydratase
C9I28_RS24495	COG1064	alcohol dehydrogenase
C9I28_RS24515	COG0583	DNA-binding transcription factor activity
C9I28_RS24535	COG2755	lipolytic protein G-D-S-L family
C9I28_RS24535	COG0657	acetylesterase activity
C9I28_RS24540	COG2205	protein histidine kinase activity
C9I28_RS24545	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
C9I28_RS24570	COG3842	ATPase activity
C9I28_RS24575	COG3842	ATPase activity
C9I28_RS24625	COG0828	Belongs to the bacterial ribosomal protein bS21 family
C9I28_RS24630	COG2081	HI0933 family
C9I28_RS24635	COG2032	superoxide dismutase activity
C9I28_RS24640	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C9I28_RS24650	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
C9I28_RS24665	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C9I28_RS24695	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
C9I28_RS24700	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C9I28_RS24715	COG3708	Transcriptional regulator
C9I28_RS24715	COG2207	Transcriptional regulator
C9I28_RS24735	COG4974	Belongs to the 'phage' integrase family
C9I28_RS24765	COG4566	intracellular signal transduction
C9I28_RS24770	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
C9I28_RS24775	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
C9I28_RS24780	COG0802	atpase or kinase
C9I28_RS24785	COG0860	N-Acetylmuramoyl-L-alanine amidase
C9I28_RS24795	COG3338	carbonate dehydratase activity
C9I28_RS24800	COG0586	Pfam SNARE associated Golgi protein
C9I28_RS24810	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
C9I28_RS24815	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
C9I28_RS24850	COG1574	metal-dependent hydrolase with the TIM-barrel fold
C9I28_RS24855	COG0477	Major facilitator Superfamily
C9I28_RS24880	COG4206	TonB-dependent receptor
C9I28_RS24885	COG2186	Transcriptional regulator
C9I28_RS24890	COG2721	sulfolactate sulfo-lyase activity
C9I28_RS24895	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C9I28_RS24940	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
C9I28_RS24945	COG2967	ApaG domain
C9I28_RS24955	COG0546	phosphoglycolate phosphatase activity
C9I28_RS24965	COG0512	Glutamine amidotransferase of anthranilate synthase
C9I28_RS24970	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C9I28_RS24980	COG0134	indole-3-glycerol-phosphate synthase activity
C9I28_RS25025	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C9I28_RS25030	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C9I28_RS25045	COG1401	restriction endodeoxyribonuclease activity
C9I28_RS25055	COG1609	Transcriptional regulator
C9I28_RS25095	COG2205	protein histidine kinase activity
C9I28_RS25125	COG4294	response to UV
C9I28_RS25140	COG0583	DNA-binding transcription factor activity
C9I28_RS25150	COG0861	Integral membrane protein TerC family
C9I28_RS25165	COG3122	Protein conserved in bacteria
C9I28_RS25210	COG0668	transmembrane transport
C9I28_RS25230	COG4191	Histidine kinase
C9I28_RS25230	COG0784	Response regulator, receiver
C9I28_RS25285	COG4716	Myosin-crossreactive antigen
C9I28_RS25395	COG3437	response regulator, receiver
C9I28_RS25395	COG0784	Response regulator, receiver
C9I28_RS25405	COG4191	Histidine kinase
C9I28_RS25420	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
C9I28_RS25425	COG0729	surface antigen
C9I28_RS25445	COG1090	epimerase
C9I28_RS25505	COG2205	protein histidine kinase activity
C9I28_RS25515	COG0519	Catalyzes the synthesis of GMP from XMP
C9I28_RS25570	COG3201	nicotinamide mononucleotide transporter
C9I28_RS25580	COG2226	methyltransferase
C9I28_RS25585	COG1404	Belongs to the peptidase S8 family
C9I28_RS25590	COG3851	Histidine kinase
C9I28_RS25595	COG2197	response regulator
C9I28_RS25610	COG2201	protein-glutamate methylesterase activity
C9I28_RS25620	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
C9I28_RS25625	COG2201	protein-glutamate methylesterase activity
C9I28_RS25630	COG0643	Histidine kinase
C9I28_RS25630	COG2198	Histidine kinase
C9I28_RS25640	COG0745	RESPONSE REGULATOR receiver
C9I28_RS25645	COG0840	transmembrane signaling receptor activity
C9I28_RS25650	COG0745	RESPONSE REGULATOR receiver
C9I28_RS25655	COG0596	Alpha beta hydrolase
C9I28_RS25680	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C9I28_RS25700	COG2188	Transcriptional regulator
C9I28_RS25715	COG1024	Enoyl-CoA hydratase
C9I28_RS25720	COG0183	Belongs to the thiolase family
C9I28_RS25725	COG1024	Enoyl-CoA hydratase
C9I28_RS25725	COG1250	3-hydroxyacyl-CoA dehydrogenase
C9I28_RS25730	COG1960	acyl-CoA dehydrogenase activity
C9I28_RS25745	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C9I28_RS25750	COG3568	Endonuclease Exonuclease Phosphatase
C9I28_RS25765	COG0494	nUDIX hydrolase
C9I28_RS25770	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
C9I28_RS25785	COG0500	methyltransferase
C9I28_RS25790	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
C9I28_RS25805	COG2226	methyltransferase
C9I28_RS25815	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C9I28_RS25820	COG4771	TonB-dependent receptor
C9I28_RS25825	COG1609	Transcriptional regulator
C9I28_RS25830	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C9I28_RS25850	COG1238	metal cluster binding
C9I28_RS25860	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
C9I28_RS25860	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
C9I28_RS25870	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
C9I28_RS25880	COG3263	regulation of cellular component size
C9I28_RS25885	COG1660	Displays ATPase and GTPase activities
C9I28_RS25895	COG1024	Enoyl-CoA hydratase
C9I28_RS25900	COG0183	Belongs to the thiolase family
C9I28_RS25910	COG1773	rubredoxin
C9I28_RS25920	COG3239	Fatty acid desaturase
C9I28_RS25925	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C9I28_RS25925	COG4221	oxidoreductase activity
C9I28_RS25925	COG0300	oxidoreductase activity
C9I28_RS25925	COG3321	synthase
C9I28_RS25940	COG0318	PFAM AMP-dependent synthetase and ligase
C9I28_RS25960	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C9I28_RS25965	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
C9I28_RS25970	COG1137	ATPase activity
C9I28_RS25975	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
C9I28_RS25985	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
C9I28_RS26030	COG3706	GGDEF domain
C9I28_RS26035	COG0633	Ferredoxin
C9I28_RS26035	COG3217	Mosc domain protein beta barrel domain protein
C9I28_RS26055	COG0012	GTP binding
C9I28_RS26080	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
C9I28_RS26085	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C9I28_RS26100	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
C9I28_RS26110	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
C9I28_RS26120	COG1194	a g-specific adenine glycosylase
C9I28_RS26130	COG0232	Belongs to the dGTPase family. Type 2 subfamily
C9I28_RS26135	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
C9I28_RS26175	COG1965	Belongs to the frataxin family
C9I28_RS26190	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
C9I28_RS26195	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
C9I28_RS26200	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C9I28_RS26205	COG1333	cytochrome c biogenesis protein
C9I28_RS26215	COG0218	Necessary for normal cell division and for the maintenance of normal septation
C9I28_RS26230	COG2814	Major facilitator Superfamily
C9I28_RS26270	COG4232	protein-disulfide reductase activity
C9I28_RS26275	COG0203	ribosomal protein L17
C9I28_RS26280	COG0202	RNA polymerase activity
C9I28_RS26285	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
C9I28_RS26290	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
C9I28_RS26295	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
C9I28_RS26300	COG0257	Belongs to the bacterial ribosomal protein bL36 family
C9I28_RS26305	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
C9I28_RS26310	COG0201	protein transport
C9I28_RS26315	COG0200	Binds to the 23S rRNA
C9I28_RS26320	COG1841	ribosomal large subunit assembly
C9I28_RS26325	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
C9I28_RS26330	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
C9I28_RS26335	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
C9I28_RS26340	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
C9I28_RS26345	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
C9I28_RS26350	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
C9I28_RS26355	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
C9I28_RS26360	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
C9I28_RS26365	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
C9I28_RS26370	COG0255	Belongs to the universal ribosomal protein uL29 family
C9I28_RS26375	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
C9I28_RS26380	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
C9I28_RS26385	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
C9I28_RS26390	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
C9I28_RS26395	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
C9I28_RS26400	COG0089	rRNA binding
C9I28_RS26405	COG0088	Forms part of the polypeptide exit tunnel
C9I28_RS26410	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
C9I28_RS26425	COG4206	TonB-dependent receptor
C9I28_RS26435	COG0051	transcription antitermination factor activity, RNA binding
C9I28_RS26440	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
C9I28_RS26445	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
C9I28_RS26450	COG0049	tRNA binding
C9I28_RS26455	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
C9I28_RS26460	COG2194	sulfuric ester hydrolase activity
C9I28_RS26475	COG1136	(ABC) transporter
C9I28_RS26480	COG1136	(ABC) transporter
C9I28_RS26480	COG0577	efflux transmembrane transporter activity
C9I28_RS26485	COG0577	efflux transmembrane transporter activity
C9I28_RS26495	COG5002	protein histidine kinase activity
C9I28_RS26510	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
C9I28_RS26550	COG0714	Associated with various cellular activities
C9I28_RS26605	COG1353	crispr-associated protein
C9I28_RS26605	COG0617	tRNA 3'-terminal CCA addition
C9I28_RS26625	COG2119	membrane
C9I28_RS26630	COG3459	Glycosyltransferase 36 associated
C9I28_RS26645	COG1522	sequence-specific DNA binding
C9I28_RS26675	COG2205	protein histidine kinase activity
C9I28_RS26675	COG0784	Response regulator, receiver
C9I28_RS26685	COG0612	Peptidase, M16
C9I28_RS26730	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
C9I28_RS26735	COG0085	RNA polymerase activity
C9I28_RS26740	COG0222	ribosome binding
C9I28_RS26745	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
C9I28_RS26750	COG0081	regulation of translation
C9I28_RS26765	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C9I28_RS26775	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
C9I28_RS26800	COG0784	Response regulator, receiver
C9I28_RS26800	COG3437	response regulator, receiver
C9I28_RS26810	COG0484	heat shock protein binding
C9I28_RS26820	COG1028	Short-chain dehydrogenase reductase Sdr
C9I28_RS26830	COG0037	tRNA processing
C9I28_RS26845	COG4771	TonB-dependent receptor
C9I28_RS26890	COG1522	sequence-specific DNA binding
C9I28_RS26910	COG0617	tRNA 3'-terminal CCA addition
C9I28_RS26925	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C9I28_RS26935	COG1950	PFAM Membrane protein of
C9I28_RS26940	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
C9I28_RS26945	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
C9I28_RS26960	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
C9I28_RS26985	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
C9I28_RS26990	COG0523	cobalamin synthesis protein
C9I28_RS27005	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
C9I28_RS27010	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
C9I28_RS27050	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
C9I28_RS27080	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C9I28_RS27085	COG0793	Belongs to the peptidase S41A family
C9I28_RS27090	COG4942	peptidase
C9I28_RS27110	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
C9I28_RS27120	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
C9I28_RS27125	COG0463	Glycosyl transferase, family 2
C9I28_RS27150	COG2205	protein histidine kinase activity
C9I28_RS27150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C9I28_RS27155	COG0596	Alpha beta hydrolase
C9I28_RS27200	COG0579	oxidoreductase
C9I28_RS27215	COG2706	6-phosphogluconolactonase activity
C9I28_RS27220	COG4948	Mandelate Racemase Muconate Lactonizing
C9I28_RS27230	COG0189	ligase activity
C9I28_RS27235	COG0006	proline dipeptidase activity
C9I28_RS27250	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
C9I28_RS27270	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C9I28_RS27355	COG2969	positive regulation of protein catabolic process
C9I28_RS27360	COG0625	glutathione transferase activity
C9I28_RS27365	COG2857	Cytochrome c1
C9I28_RS27370	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
C9I28_RS27375	COG0723	plastoquinol--plastocyanin reductase activity
C9I28_RS27380	COG1970	mechanosensitive ion channel activity
C9I28_RS27395	COG0583	DNA-binding transcription factor activity
C9I28_RS27400	COG0473	3-isopropylmalate dehydrogenase activity
C9I28_RS27460	COG4964	Belongs to the GSP D family
C9I28_RS27505	COG1703	isobutyryl-CoA mutase activity
C9I28_RS27505	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
C9I28_RS27505	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
C9I28_RS27525	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C9I28_RS27545	COG4989	oxidoreductase activity
C9I28_RS27550	COG1183	phosphatidylcholine synthase activity
C9I28_RS27570	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
C9I28_RS27575	COG0706	membrane insertase activity
C9I28_RS27580	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
C9I28_RS27585	COG0594	ribonuclease P activity
C9I28_RS27590	COG0230	Belongs to the bacterial ribosomal protein bL34 family